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Affiliation: University of Foggia
Morotti A, Rocca S, Carrà G, Saglio G, Brancaccio M. Modeling myeloproliferative neoplasms: From mutations to mouse models and back again. Blood Rev. 2017;31:139-150 pubmed publisher
..This review focuses on MPN mouse models specifically developed to assess the pathogenetic roles of gene mutations found in human patients, as well as murine MPN-like phenotypes identified in genetically modified mice. ..
Carrà G, Crivellaro S, Taulli R, Guerrasio A, Saglio G, Morotti A. Mechanisms of p53 Functional De-Regulation: Role of the I?B-?/p53 Complex. Int J Mol Sci. 2016;17: pubmed
..Here, we review the mechanisms of p53 functional inactivation, with a particular emphasis on the interaction between p53 and I?B-?, the NFKBIA gene product. ..