A Carpi

Summary

Affiliation: University of Pisa
Country: Italy

Publications

  1. ncbi request reprint Utility of a serum tumour marker panel in the post-operative follow-up of breast cancer patients with equivocal conventional radiological examinations
    Andrea Nicolini
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    Tumour Biol 24:275-80. 2003
  2. ncbi request reprint Large-needle percutaneous aspiration biopsy of the testicle in men with nonobstructive azoospermia
    Angelo Carpi
    Department of Reproduction and Ageing, Division of Andrology, University of Pisa, Pisa, Italy
    Fertil Steril 86:464-5. 2006
  3. doi request reprint Large needle aspiration biopsy histology for preoperative selection of Hürthle cell thyroid nodules
    Angelo Carpi
    Department of Reproduction and Ageing, University of Pisa, Pisa, Italy
    Histopathology 59:892-6. 2011
  4. ncbi request reprint Thyroid nodule evaluation: what have we really learned from recent clinical guidelines?
    A Carpi
    Department of Reproduction and Ageing, University of Pisa, Italy
    Biomed Pharmacother 60:393-5. 2006
  5. doi request reprint Controversies in the management of nonobstructive azoospermia
    Angelo Carpi
    Department of Reproduction and Ageing, University of Pisa, Pisa, Italy
    Fertil Steril 91:963-70. 2009
  6. doi request reprint Thyroid tumor marker genomics and proteomics: diagnostic and clinical implications
    Angelo Carpi
    Department of Reproduction and Ageing, University of Pisa, Pisa, Italy
    J Cell Physiol 224:612-9. 2010
  7. ncbi request reprint Large needle aspiration biopsy results of palpable thyroid nodules diagnosed by fine-needle aspiration as a microfollicular nodule with atypical cells or suspected cancer
    Angelo Carpi
    Department of Reproduction, University of Pisa, Spedali Santra Chiara, Via Roma 67, 56126, Italy
    Biomed Pharmacother 58:351-5. 2004
  8. ncbi request reprint Cytokines in the management of high risk or advanced breast cancer: an update and expectation
    A Carpi
    Department of Reproduction and Ageing, 56126 Pisa, Italy
    Curr Cancer Drug Targets 9:888-903. 2009
  9. doi request reprint Thyroid fine needle aspiration: how to improve clinicians' confidence and performance with the technique
    A Carpi
    Department of Reproduction and Ageing, University Hospital, Ospedale Santa Chiara, Via Roma, 67, 56126 Pisa, Italy
    Cancer Lett 264:163-71. 2008
  10. doi request reprint Galectin-3 detection on large-needle aspiration biopsy improves preoperative selection of thyroid nodules: a prospective cohort study
    Angelo Carpi
    Department of Reproduction and Ageing, University of Pisa, Pisa, Italy
    Ann Med 42:70-8. 2010

Collaborators

Detail Information

Publications108 found, 100 shown here

  1. ncbi request reprint Utility of a serum tumour marker panel in the post-operative follow-up of breast cancer patients with equivocal conventional radiological examinations
    Andrea Nicolini
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    Tumour Biol 24:275-80. 2003
    ..Clinical data of 427 breast cancer patients submitted to an intensive follow-up after mastectomy between January 1986 and December 2000 were retrospectively reviewed...
  2. ncbi request reprint Large-needle percutaneous aspiration biopsy of the testicle in men with nonobstructive azoospermia
    Angelo Carpi
    Department of Reproduction and Ageing, Division of Andrology, University of Pisa, Pisa, Italy
    Fertil Steril 86:464-5. 2006
    ..2 x 0.3 x 0.62 cm, 385 mg, and 63%, respectively) were similar to those obtained by open or other surgical biopsy techniques that were used for assisted fertilization in the same type of patients...
  3. doi request reprint Large needle aspiration biopsy histology for preoperative selection of Hürthle cell thyroid nodules
    Angelo Carpi
    Department of Reproduction and Ageing, University of Pisa, Pisa, Italy
    Histopathology 59:892-6. 2011
    ....
  4. ncbi request reprint Thyroid nodule evaluation: what have we really learned from recent clinical guidelines?
    A Carpi
    Department of Reproduction and Ageing, University of Pisa, Italy
    Biomed Pharmacother 60:393-5. 2006
    ....
  5. doi request reprint Controversies in the management of nonobstructive azoospermia
    Angelo Carpi
    Department of Reproduction and Ageing, University of Pisa, Pisa, Italy
    Fertil Steril 91:963-70. 2009
    ..As a result, any progress in optimizing these techniques must involve delineation of specific selection criteria for each NOA patient...
  6. doi request reprint Thyroid tumor marker genomics and proteomics: diagnostic and clinical implications
    Angelo Carpi
    Department of Reproduction and Ageing, University of Pisa, Pisa, Italy
    J Cell Physiol 224:612-9. 2010
    ..This can be rectified with large needle aspiration biopsy (LNAB) techniques and is exemplified by the favorable performance of galectin-3 determinations on LNAB specimens...
  7. ncbi request reprint Large needle aspiration biopsy results of palpable thyroid nodules diagnosed by fine-needle aspiration as a microfollicular nodule with atypical cells or suspected cancer
    Angelo Carpi
    Department of Reproduction, University of Pisa, Spedali Santra Chiara, Via Roma 67, 56126, Italy
    Biomed Pharmacother 58:351-5. 2004
    ..0007). These data suggest that LNAB can be used for the preoperative selection of the palpable thyroid nodules diagnosed by FNA as a microfollicular nodule with atypical cells or suspected cancer...
  8. ncbi request reprint Cytokines in the management of high risk or advanced breast cancer: an update and expectation
    A Carpi
    Department of Reproduction and Ageing, 56126 Pisa, Italy
    Curr Cancer Drug Targets 9:888-903. 2009
    ..If this immunotherapy prolongs survival of endocrine dependent metastatic breast cancer patients, IL-2 and IFNbeta can also be evaluated as adjuvant treatment of patients with positive estrogen receptors...
  9. doi request reprint Thyroid fine needle aspiration: how to improve clinicians' confidence and performance with the technique
    A Carpi
    Department of Reproduction and Ageing, University Hospital, Ospedale Santa Chiara, Via Roma, 67, 56126 Pisa, Italy
    Cancer Lett 264:163-71. 2008
    ..Therefore, we propose that clinical practice guidelines reflect these adjuvant techniques to thyroid FNA in order to improve selection criteria for thyroid nodule surgery...
  10. doi request reprint Galectin-3 detection on large-needle aspiration biopsy improves preoperative selection of thyroid nodules: a prospective cohort study
    Angelo Carpi
    Department of Reproduction and Ageing, University of Pisa, Pisa, Italy
    Ann Med 42:70-8. 2010
    ..New techniques of improving diagnostic reliability of thyroid nodules are needed...
  11. ncbi request reprint Fine-needle and large-needle percutaneous aspiration biopsy of testicles in men with nonobstructive azoospermia: safety and diagnostic performance
    Angelo Carpi
    Department of Reproduction and Aging, University of Pisa, Spedali Riuniti Santa Chiara, Via Roma 67, 56126 Pisa, Italy
    Fertil Steril 83:1029-33. 2005
    ....
  12. ncbi request reprint Percutaneous large-needle aspiration biopsy histology of palpable thyroid nodules: technical and diagnostic performance
    A Carpi
    Department of Reproduction and Ageing, University Hospital, Pisa, Italy
    Histopathology 51:249-57. 2007
    ..To report original and review existing data on safety and performance of large-needle aspiration biopsy (LNAB) histology in the preoperative selection of palpable thyroid nodule...
  13. doi request reprint Percutaneous biopsy of the testicle: a mini review with a proposal flow chart for non-obstructive azoospermia
    Angelo Carpi
    Department of Reproduction and Ageing, University of Pisa, Pisa, Italy
    Ann Med 43:83-9. 2011
    ..An operative flow chart is proposed for the management of NOA in which FNAB, LNAB and open surgical biopsy are used for the optimal management of NOA...
  14. ncbi request reprint Large needle percutaneous aspiration biopsy of the testicle in men with nonobstructive azoospermia: technical performance
    Angelo Carpi
    Department of Reproduction and Aging, University of Pisa, Pisa, Italy
    Biomed Pharmacother 60:557-60. 2006
    ..needle seemed to offer the best performance in the larger testicles, while in the medium and lower sized testicles the smaller 22 g. needle gave results comparable to or slightly better than the other larger needles...
  15. ncbi request reprint Effect of L-thyroxine treatment on left ventricular function in subclinical hypothyroidism
    F Franzoni
    Department of Internal Medicine, University of Pisa, Via Roma 67, Pisa, Italy
    Biomed Pharmacother 60:431-6. 2006
    ..L-T4 replacement therapy should be advised for these patients with the aim to correct preclinical cardiac dysfunction and prevent the development of clinically significant myocardial dysfunction...
  16. ncbi request reprint Endothelial function in young subjects with vaso-vagal syncope
    F Galetta
    Department of Internal Medicine, University of Pisa, Via Roma 67, Pisa, Italy
    Biomed Pharmacother 60:448-52. 2006
    ..The aim of this study was to determine whether endothelial function and inappropriate peripheral vasomotion have a significant role in the pathogenesis of neurally mediated syncope...
  17. doi request reprint Changes in autonomic regulation and ventricular repolarization induced by subclinical hyperthyroidism
    F Galetta
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    Biomed Pharmacother 64:546-9. 2010
    ..The aim of the present study was to evaluate the effect of subclinical hyperthyroidism (SHT) on cardiovascular autonomic function and ventricular repolarization...
  18. ncbi request reprint Post-ischaemic peak flow and myogenic flowmotion component are independent variables for skin post-ischaemic reactive hyperaemia in healthy subjects
    M Rossi
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56100 Pisa, Italy
    Microvasc Res 74:9-14. 2007
    ..These findings suggest that not only increased shear stress but also post-ischaemic amplification of myogenic SBF component independently contributes to the more prolonged phase of post-ischaemic skin re-perfusion in healthy subjects...
  19. ncbi request reprint Absent post-ischemic increase of blood flowmotion in the cutaneous microcirculation of healthy chronic cigarette smokers
    M Rossi
    Department of Internal Medicine, University of Pisa, Italy
    Clin Hemorheol Microcirc 36:163-71. 2007
    ....
  20. pmc The role of tumour markers in improving the accuracy of conventional chest X-ray and liver echography in the post-operative detection of thoracic and liver metastases from breast cancer
    A Nicolini
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    Br J Cancer 83:1412-7. 2000
    ..3 tumour marker panel has a high value for selecting those patients at high risk of developing clinically evident pulmonary or liver metastases from amongst those subjects with equivocal CXR or equivocal LE...
  21. doi request reprint Study of skin vasomotion during phollicular and luteal phase in young healthy women
    M Rossi
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    Clin Hemorheol Microcirc 42:107-15. 2009
    ....
  22. ncbi request reprint Cancer stem cells: perspectives of new therapeutical approaches for breast cancer
    A Nicolini
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    Front Biosci (Schol Ed) 3:1486-99. 2011
    ..Here all these novel approaches related to breast cancer stem cells are described...
  23. ncbi request reprint Large-needle aspiration biopsy for the preoperative selection of palpable thyroid nodules diagnosed by fine-needle aspiration as a microfollicular nodule or suspected cancer
    A Carpi
    Department of Reproduction and Aging, University of Pisa, Italy
    Am J Clin Pathol 113:872-7. 2000
    ..These data indicate that histologic examination of the LNAB specimen can be used for preoperative selection of thyroid nodules diagnosed by FNA as a microfollicular nodule or suspected cancer...
  24. ncbi request reprint Vascular endothelial growth factor (VEGF) and other common tissue prognostic indicators in breast cancer: a case-control study
    A Nicolini
    Department of Internal Medicine, University of Pisa, Italy
    Int J Biol Markers 19:275-81. 2004
    ..018 to 0.001). In conclusion, tissue VEGF does not seem a suitable candidate to replace conventional histological and other common biological prognostic factors in breast cancer...
  25. ncbi request reprint Skin microcirculatory effect of exogenous calcitonin gene-related peptide (CGRP) evaluated by laser Doppler flowmetry coupled with iontophoresis in healthy subjects
    M Rossi
    Department of Internal Medicine, University of Pisa, Italy
    Microvasc Res 73:124-30. 2007
    ....
  26. ncbi request reprint Metastatic breast cancer: an updating
    A Nicolini
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    Biomed Pharmacother 60:548-56. 2006
    ..This article reports on recent advances on metastatic breast cancer. Detection, prognostic factors, predictors of response to therapy and therapy, with particular regard to targeted therapies, were examined...
  27. ncbi request reprint Spectral analysis of skin blood flowmotion before and after exercise in healthy trained and in sedentary subjects
    M Rossi
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    Int J Sports Med 27:540-5. 2006
    ..This can favour a greater reduction of resistance in skin microvascular networks during exercise and consequently an increase of its capacity to transport and eliminate heat...
  28. pmc Large needle aspiration biopsy and galectin-3 determination in selected thyroid nodules with indeterminate FNA-cytology
    A Carpi
    Department of Reproduction, University of Pisa, Pisa 56024, Italy
    Br J Cancer 95:204-9. 2006
    ..6, 97.2 and 95.3%, respectively. In conclusion, LNAB plus galectin-3 expression analysis when applied preoperatively to selected thyroid nodules candidate to surgery can potentially reduce unnecessary thyroid resections...
  29. ncbi request reprint Ambulatory blood pressure monitoring and endothelium-dependent vasodilation in the elderly athletes
    F Galetta
    Department of Internal Medicine, University of Pisa, Via Roma 67, Pisa, Italy
    Biomed Pharmacother 60:443-7. 2006
    ..Aim of the present study was to evaluate in elderly athletes the effect of regular aerobic exercise on arterial blood pressure (BP) and on endothelium-dependent flow-mediated dilation (FMD) of the brachial artery...
  30. pmc The role of tumour markers in predicting skeletal metastases in breast cancer patients with equivocal bone scintigraphy
    A Nicolini
    Department of Internal Medicine, University of Pisa, Italy
    Br J Cancer 79:1443-7. 1999
    ..3 tumour marker panel has a high value in selecting those patients with bone metastases, or at high risk of developing clinically-evident bone metastases, among the large number of subjects with equivocal BS...
  31. ncbi request reprint Stem cells: their role in breast cancer development and resistance to treatment
    A Nicolini
    Department of Internal Medicine, University of Pisa, Italy
    Curr Pharm Biotechnol 12:196-205. 2011
    ..The reasons for CSC resistance to chemotherapy, hormone therapy and radiotherapy also have been examined and they opened new scenarios for cancer therapy...
  32. ncbi request reprint The investigation of skin blood flowmotion: a new approach to study the microcirculatory impairment in vascular diseases?
    M Rossi
    Department of Internal Medicine, Department of Reproduction and Ageing, University of Pisa, Via Roma, 67, Pisa, Italy
    Biomed Pharmacother 60:437-42. 2006
    ....
  33. ncbi request reprint Aspiration needle biopsy in preoperative selection of thyroid nodules defined at fine-needle aspiration as microfollicular lesions
    A Carpi
    Department of Reproduction and Aging, University of Pisa, Italy
    Am J Clin Oncol 22:65-9. 1999
    ....
  34. ncbi request reprint Effect of chronic aerobic exercise on cutaneous microcirculatory flow response to insulin iontophoresis and to ischemia in elderly males
    M Rossi
    Department of Internal Medicine, University of Pisa, Italy
    Int J Sports Med 26:558-62. 2005
    ..5 +/- 28.5 s versus 20.0 +/- 9.3 s, p < 0.05, respectively). These results suggest that chronic aerobic exercise increases insulin vasodilatory activity and improves endothelial function in elderly subjects...
  35. doi request reprint Skin vasomotion investigation: a useful tool for clinical evaluation of microvascular endothelial function?
    M Rossi
    Department of Internal Medicine, University of Pisa, School of Medicine, Pisa, Italy
    Biomed Pharmacother 62:541-5. 2008
    ..Further studies are needed to evaluate whether the investigation of skin endothelial-dependent vasomotion can predict clinical and therapeutic outcomes of patients with vascular diseases...
  36. ncbi request reprint Heart rate variability and QT dispersion in patients with subclinical hypothyroidism
    F Galetta
    Department of Internal Medicine, University of Pisa, Via Roma, 67, Pisa, Italy
    Biomed Pharmacother 60:425-30. 2006
    ..The aim of the present study was to evaluate the dispersion of QT interval, i.e. an index of inhomogeneity of repolarization, and heart rate variability (HRV), i.e. a measure of cardiac autonomic modulation, in SH patients...
  37. ncbi request reprint A percutaneous large-needle aspiration biopsy technique for histologic examination of the testis in infertile patients
    A Carpi
    Department of Reproduction and Aging, University of Pisa, Italy
    Fertil Steril 71:756-60. 1999
    ..To describe a relatively new percutaneous large-needle aspiration biopsy technique for histologic examination of the testis in infertile patients...
  38. ncbi request reprint Controversies in diagnostic approaches to the indeterminate follicular thyroid nodule
    A Carpi
    Internal Medicine Department, University of Pisa Medical School, Pisa, Italy
    Biomed Pharmacother 59:517-20. 2005
    ..Among the techniques that may improve preoperative diagnostic accuracy are large needle aspiration biopsy and immunohistochemistry for galectin-3...
  39. pmc Evaluation of serum CA15-3 determination with CEA and TPA in the post-operative follow-up of breast cancer patients
    A Nicolini
    Institute of 2nd Medical Clinic, University of Pisa, Italy
    Br J Cancer 64:154-8. 1991
    ..Contemporaneous measurement of serum CEA levels only slightly increases sensitivity and positive predictive value of TPA-CA15-3 combination...
  40. ncbi request reprint Oral low-dose cyclophosphamide in metastatic hormone refractory prostate cancer (MHRPC)
    A Nicolini
    Department of Internal Medicine, University of Pisa, Via Roma 67, Pisa 56126, Italy
    Biomed Pharmacother 58:447-50. 2004
    ..So it can be an useful option before or after the use of other single or combined potentially active chemotherapeutic agents...
  41. ncbi request reprint Serum thyroglobulin measurement: clinical background and main methodological aspects with clinical impact
    A Iervasi
    National Council of Research, Institute of Clinical Physiology, Via Moruzzi, Pisa, Italy
    Biomed Pharmacother 60:414-24. 2006
    ....
  42. doi request reprint Total parathyroidectomy without autotransplantation for the treatment of secondary hyperparathyroidism associated with chronic kidney disease: clinical and laboratory long-term follow-up
    M Puccini
    Department of Surgery, AOUP, S Chiara Hospital, Pisa, Italy
    Biomed Pharmacother 64:359-62. 2010
    ..tPTX should be considered a safe and successful procedure for the treatment of severe secondary hyperparathyroidism associated with chronic kidney disease...
  43. ncbi request reprint Skin blood flowmotion response to insulin iontophoresis in normal subjects
    M Rossi
    Department of Internal Medicine, University of Pisa, Italy
    Microvasc Res 70:17-22. 2005
    ....
  44. doi request reprint Thyroid hormones and the cardiovascular system: pathophysiology and interventions
    G Cini
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    Biomed Pharmacother 63:742-53. 2009
    ..In addition, empiric treatment with thyroid hormone analogues or T3 represent emergent and highly controversial interventions...
  45. ncbi request reprint Cytokines in breast cancer
    A Nicolini
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    Cytokine Growth Factor Rev 17:325-37. 2006
    ....
  46. ncbi request reprint Postoperative follow-up of breast cancer patients: overview and progress in the use of tumor markers
    A Nicolini
    Department of Internal Medicine, Oncological Consulting Room and Department of Reproduction and Aging, University of Pisa, Italy
    Tumour Biol 21:235-48. 2000
    ..It is hoped that these data will stimulate further trials including TAA in the follow-up of breast cancer patients...
  47. doi request reprint Immunotherapy prolongs the serum CEA-TPA-CA15.3 lead time at the metastatic progression in endocrine-dependent breast cancer patients: a retrospective longitudinal study
    A Nicolini
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    Cancer Lett 263:122-9. 2008
    ..05). The CEA-TPA-CA15.3 tumour marker panel accurately predicted metastatic disease progression and immunotherapy significantly prolonged the CEA-TPA-CA15.3 lead time. This can be used for anticipating salvage treatment in these patients...
  48. pmc Prolonged survival by 'early' salvage treatment of breast cancer patients: a retrospective 6-year study
    A Nicolini
    Institute of 2nd Medical Clinic, University of Pisa, Italy
    Br J Cancer 76:1106-11. 1997
    ..Randomized prospective trials must be encouraged to confirm these data and to better evaluate the effect on the disease-free survival (DFS) and overall survival (OS) of 'early' salvage treatment protocols...
  49. ncbi request reprint Cytokine secretion in nasal mucus of normal subjects and patients with allergic rhinitis
    M C Scavuzzo
    Dipartimento di Morfologia Umana e Biologia Applicata, Universita di Pisa, Via Roma 67, 56126 Pisa, Italy
    Biomed Pharmacother 57:366-71. 2003
    ....
  50. ncbi request reprint Spectral analysis of skin laser Doppler blood perfusion signal during cutaneous hyperemia in response to acetylcholine iontophoresis and ischemia in normal subjects
    M Rossi
    Department of Internal Medicine, University of Pisa, Italy
    Clin Hemorheol Microcirc 31:303-10. 2004
    ..These data suggest that ACh iontophoresis test is more adequate than post-ischemic hyperemia test in exploring the skin microcirculatory endothelial function in normal subjects...
  51. ncbi request reprint Inflammatory mediators and eosinophilia in atopic and non-atopic patients with nasal polyposis
    M C Scavuzzo
    Dipartimento di Morfologia Umana e Biologia Applicata, Facolta di Medicina e Chirurgia, Universita di Pisa, Pisa, Italy
    Biomed Pharmacother 59:323-9. 2005
    ..7 vs. 605.5 pg/ml+/-481.1; P < 0.015). These findings suggest that inflammation still remains the major factor in the etiology of nasal polyposis and show different levels of inflammatory mediators into atopic and non-atopic patients...
  52. ncbi request reprint C-reactive protein in patients on chronic hemodialysis with different techniques and different membranes
    V Panichi
    Department of Internal Medicine, University of Pisa, Italy
    Biomed Pharmacother 60:14-7. 2006
    ..moreover, an important effect on CRP of the hemodialysis membrane is observed and new synthetic membranes can be used to decrease these levels...
  53. ncbi request reprint Effect of nebivolol on QT dispersion in hypertensive patients with left ventricular hypertrophy
    F Galetta
    Department of Internal Medicine, University of Pisa School of Medicine, Via Roma 67 56126 Pisa, Italy
    Biomed Pharmacother 59:15-9. 2005
    ..This effect, occurred without any change in LVM, did not seem to be related to the blood pressure lowering and could contribute to reduce arrhythmias as well as sudden cardiac death in at-risk hypertensive patients...
  54. ncbi request reprint Insulin resistance and low urinary citrate excretion in calcium stone formers
    A Cupisti
    Department of Internal Medicine, Nephrology Unit, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    Biomed Pharmacother 61:86-90. 2007
    ..This finding suggests the need for a careful metabolic assessment in patients known to form calcium stones in order to ensure stone recurrence prevention and cardiovascular protection...
  55. ncbi request reprint Skin microcirculation in peripheral arterial obliterative disease
    M Rossi
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56100 Pisa, Italy
    Biomed Pharmacother 58:427-31. 2004
    ..This integrated skin microcirculatory diagnostic approach can be used for a better management of PAOD patients...
  56. ncbi request reprint Skin blood flowmotion and microvascular reactivity investigation in hypercholesterolemic patients without clinically manifest arterial diseases
    M Rossi
    Dipartimento di Medicina Interna, Universita degli Studi di Pisa, Pisa, Italia
    Physiol Res 58:39-47. 2009
    ..01-0.02 Hz SBF subinterval in HP suggests a skin endothelial dysfunction in these patients. This SBF abnormality showed a tendency to improve after rosuvastatin therapy in eleven treated patients...
  57. doi request reprint Dedifferentiated thyroid cancer: a therapeutic challenge
    Alessandro Antonelli
    Department of Internal Medicine, University of Pisa, School of Medicine, Via Roma, 67, I 56100 Pisa, Italy
    Biomed Pharmacother 62:559-63. 2008
    ..In fact, chemosensitivity tests in primary tumoral cells may help in detecting responsive patients and in preventing the administration of inactive drugs to those unresponsive...
  58. doi request reprint Immune manipulation of advanced breast cancer: an interpretative model of the relationship between immune system and tumor cell biology
    Andrea Nicolini
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    Med Res Rev 29:436-71. 2009
    ..Tumor growth, defective immunorecognition and immunosuppression are the three principal effects considered responsible for immune evasion...
  59. doi request reprint CXCL10 and CCL2 chemokine serum levels in patients with hepatitis C associated with autoimmune thyroiditis
    Alessandro Antonelli
    Department of Internal Medicine, University of Pisa School of Medicine, Pisa, Italy
    J Interferon Cytokine Res 29:345-51. 2009
    ....
  60. ncbi request reprint Relationship of cellular immunity, cytokines and CRP with clinical course in breast cancer patients with endocrine-dependent distant metastases treated with immunotherapy
    Andrea Nicolini
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    Cancer Lett 251:330-8. 2007
    ..Furthermore, these results demonstrate that different changes of proinflammatory cytokines, CRP and inhibiting factors are consistent with associated clinical benefit or with disease progression, respectively...
  61. doi request reprint Alpha-chemokine CXCL10 and beta-chemokine CCL2 serum levels in patients with hepatitis C-associated cryoglobulinemia in the presence or absence of autoimmune thyroiditis
    Alessandro Antonelli
    Department of Internal Medicine, University of Pisa School of Medicine, I 56100 Pisa, Italy
    Metabolism 57:1270-7. 2008
    ..Future studies in larger series will be needed to evaluate the potential usefulness of serum CXCL10 and CCL2 determination as a prognostic marker in the follow-up of MC patients, also in relation to the presence of AT...
  62. doi request reprint In vitro and in vivo study on the antioxidant activity of dexrazoxane
    Fabio Galetta
    Department of Internal Medicine, University of Pisa, Via Roma, 67, 56126 Pisa, Italy
    Biomed Pharmacother 64:259-63. 2010
    ..Aim of the present study was to assess the in vitro and in vivo antioxidant effects of dexrazoxane...
  63. ncbi request reprint Controlled navigation of endoscopic capsules: concept and preliminary experimental investigations
    Federico Carpi
    Interdepartmental Research Centre E Piaggio, School of Engineering, University of Pisa, Via Diotisalvi, 2, 56100 Pisa, Italy
    IEEE Trans Biomed Eng 54:2028-36. 2007
    ..The use of a new instrumentation, recently developed for cardiovascular treatments, is proposed as a potential means enabling the application of controlled magnetic fields for intrabody navigations...
  64. ncbi request reprint Vascular endothelial growth factor and its soluble receptor in benign and malignant ovarian tumors
    Paolo Giovanni Artini
    Department of Reproductive Medicine and Child Development, Division of Obstetrics and Gynecology, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    Biomed Pharmacother 62:373-7. 2008
    ..In conclusion, all in all, our data indicate that an excess of local VEGF with respect to its soluble receptor VEGFR-1 may be a key factor in the onset and maintenance of pathological neo-angiogenesis in ovarian cyst formation...
  65. doi request reprint A new pharmacological approach to gastrointestinal cancer at high risk of relapse based on maintenance of the cytostatic effect
    Andrea Nicolini
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56126, Pisa, Italy
    Tumour Biol 31:523-32. 2010
    ..8% and 40.1%, respectively. These findings suggest that this new pharmacological approach based on the long-term maintenance of a cytostatic effect with 5-FU-LV can produce a relevant improvement in the outcome of this population...
  66. ncbi request reprint Carotid integrated backscatter analysis in patients with subclinical hypothyroidism
    Ferdinando Franzoni
    Department of Internal Medicine, University of Pisa School of Medicine, Via Roma 67, 56126 Pisa, Italy
    Clin Endocrinol (Oxf) 68:278-83. 2008
    ....
  67. ncbi request reprint Conventional and new emerging prognostic factors in breast cancer: an update
    Andrea Nicolini
    University of Pisa, Department of Internal Medicine, Via Roma 67, 56126 Pisa, Italy
    Biomark Med 1:525-40. 2007
    ..So far, different gene-expression patterns with different prognoses have been identified but methodological problems remain to be solved prior to routine use...
  68. doi request reprint Effect of telmisartan on QT interval variability and autonomic control in hypertensive patients with left ventricular hypertrophy
    Fabio Galetta
    Department of Internal Medicine, University of Pisa, Via Roma, 67, 56126 Pisa, Italy
    Biomed Pharmacother 64:516-20. 2010
    ..The aim of the study was to examine the effect of the antihypertensive AT1 receptors antagonist telmisartan on cardiovascular autonomic function and QT dispersion in hypertensive patients with LVH...
  69. ncbi request reprint Acute effects of hemodialysis on left ventricular function evaluated by tissue Doppler imaging
    Fabio Galetta
    Department of Internal Medicine, University of Pisa School of Medicine, Via Roma, 67, 56126 Pisa, Italy
    Biomed Pharmacother 60:66-70. 2006
    ..These findings suggest that low ultrafiltration volume and/or limited interdialytic weight gain are cardioprotective measures in hemodialysis patients...
  70. ncbi request reprint Biomolecular markers of breast cancer
    Andrea Nicolini
    Department of Internal Medicine, University of Pisa, Italy
    Front Biosci 11:1818-43. 2006
    ..In conclusion, biomolecular markers are improving understanding of biology and management of breast cancer...
  71. ncbi request reprint Left ventricular diastolic function and carotid artery wall in elderly athletes and sedentary controls
    Fabio Galetta
    Department of Internal Medicine, University of Pisa School of Medicine, Via Roma, 67, 56126 Pisa, Italy
    Biomed Pharmacother 58:437-42. 2004
    ..It would appear that pulsed TDI and IBS analysis may play an important role in detecting training-induced LV and carotid artery structural and functional modifications...
  72. ncbi request reprint Plasma antioxidant activity and cutaneous microvascular endothelial function in athletes and sedentary controls
    Ferdinando Franzoni
    Department of Internal Medicine, University of Pisa School of Medicine, Via Roma, 67, 56100 Pisa, Italy
    Biomed Pharmacother 58:432-6. 2004
    ..r = 0.41, P <0.01). In conclusion, these results suggest that regular physical activity is associated with a better microvascular endothelial function in older athletes probably due to increased antioxidant defenses...
  73. ncbi request reprint Beta-interferon and interleukin-2 prolong more than three times the survival of 26 consecutive endocrine dependent breast cancer patients with distant metastases: an exploratory trial
    Andrea Nicolini
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    Biomed Pharmacother 59:253-63. 2005
    ..Hormone immuno-therapy was given in an outpatient setting and was very well tolerated. These data suggest that immuno-therapy plays an important role in endocrine-dependent metastatic breast cancer...
  74. ncbi request reprint An immunotherapy schedule in endocrine-dependent metastatic breast cancer: correlation between clinical course and immunologic parameters
    Andrea Nicolini
    Department of Internal Medicine, University of Pisa, 56126 Pisa Italy
    J Immunother 28:276-9. 2005
    ....
  75. ncbi request reprint Epidemiological and clinical features of 139 patients with tuberculosis at a teaching hospital in Italy (Pisa, 1996-2000)
    Mario Bonadio
    Department of Medicine, Infectious Diseases Section, University Hospital of Pisa, Italy
    Biomed Pharmacother 59:127-31. 2005
    ..The rate of extrapulmonary TB shows a trend to increase accordingly to recent literature. The isolation rate of multidrug-resistant strains of M. tuberculosis in Pisa seems to be similar to the rates reported in other areas of Europe...
  76. ncbi request reprint Responses to Tilt test in young and elderly patients with syncope of unknown origin
    Fabio Galetta
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56126, Pisa, Italy
    Biomed Pharmacother 58:443-6. 2004
    ....
  77. ncbi request reprint Serum tumor markers in the management of ovarian, endometrial and cervical cancer
    Angiolo Gadducci
    Division of Gynecology and Obstetrics, Department of Procreative Medicine and Child Development, University of Pisa, Via Roma 67, 56127, Pisa, Italy
    Biomed Pharmacother 58:24-38. 2004
    ..Elevated CA 125 levels can be often detected in patients with cervical adenocarcinoma. The future for tumor marker research is represented by the emerging technologies of transcriptional profiling and proteomics...
  78. ncbi request reprint "Tumour marker guided" salvage treatment prolongs survival of breast cancer patients: final report of a 7-year study
    Andrea Nicolini
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    Biomed Pharmacother 57:452-9. 2003
    ..3) tumour marker panel is sensitive enough for significantly anticipating salvage treatment and prolonging survival of relapsing breast cancer patients...
  79. ncbi request reprint Skin vasoreactivity to insulin iontophoresis is reduced in elderly subjects and is absent in treated non-insulin-dependent diabetes patients
    Marco Rossi
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56100 Pisa, Italy
    Biomed Pharmacother 58:560-5. 2004
    ..The local skin vasodilatatory effect induced by insulin seems to involve mechanisms different from those underlying the skin postischemic hyperemia...
  80. ncbi request reprint Spectral analysis of laser Doppler skin blood flow oscillations in human essential arterial hypertension
    Marco Rossi
    University of Pisa
    Microvasc Res 72:34-41. 2006
    ..The same findings also suggest that the impairment of the endothelial mechanism involved in SBF control occurs by the time in the course of EHT...
  81. pmc Intensive post-operative follow-up of breast cancer patients with tumour markers: CEA, TPA or CA15.3 vs MCA and MCA-CA15.3 vs CEA-TPA-CA15.3 panel in the early detection of distant metastases
    Andrea Nicolini
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    BMC Cancer 6:269. 2006
    ..As high sensitivity and specificity and different cut-off values have been reported for mucin-like carcinoma associated antigen (MCA), we compared MCA with the above mentioned tumour markers and MCA-CA15.3 with the CEA-TPA-CA15.3 panel...
  82. ncbi request reprint Effect of epirubicin-based chemotherapy and dexrazoxane supplementation on QT dispersion in non-Hodgkin lymphoma patients
    Fabio Galetta
    Department of Internal Medicine, University of Pisa School of Medicine, Via Roma, 67, Italy
    Biomed Pharmacother 59:541-4. 2005
    ..Prolongation of QT dispersion may not only represent a sensitive tool in identifying the first sign of anthracycline-induced cardiotoxicity, but it may serve also in identifying patients who are at risk of arrhythmic events...
  83. ncbi request reprint Spermatogenesis in azoospermic, formerly cryptorchid men. Use of needle aspiration techniques
    Angelo Carpi
    Divisions of Andrology, Department of Reproduction and Aging, University of Pisa, Pisa, Italy
    Acta Cytol 46:848-54. 2002
    ..To assess the use of testicular needle aspiration techniques to evaluate fertility potential in azoospermic, formerly cryptorchid men...
  84. ncbi request reprint An in vitro study of the peroxyl and hydroxyl radical scavenging capacity of the calcium antagonist amlodipine
    Ferdinando Franzoni
    Department of Internal Medicine, University of Pisa, Via Roma, 67, 56100 Pisa, Italy
    Biomed Pharmacother 58:423-6. 2004
    ..Amlodipine has intrinsic antioxidant activity with both anti-hydroxyl and anti-peroxyl radicals activity...
  85. ncbi request reprint Magnetic shells for gastrointestinal endoscopic capsules as a means to control their motion
    Federico Carpi
    Interdepartmental Research Centre E Piaggio, University of Pisa, School of Engineering, Via Diotisalvi, Pisa, Italy
    Biomed Pharmacother 60:370-4. 2006
    ..These tests permitted to demonstrate translations, rotations and roto-translations of the capsule/shell complex onto pieces of bovine tissues...
  86. ncbi request reprint Advanced breast cancer: an update and controversies on diagnosis and therapy
    A Nicolini
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    Biomed Pharmacother 57:439-46. 2003
    ..Furthermore, the options and associations of the drug therapy available for treatment of advanced breast cancer have been reviewed...
  87. ncbi request reprint Long-term monitoring of cell-mediated immunity in disease-free breast cancer patients: a preliminary retrospective study
    A Nicolini
    Department of Internal Medicine, University of Pisa, Italy
    Biomed Pharmacother 56:339-44. 2002
    ..The prolonged disease-free interval observed in the 34 N- and 11 N+ breast cancer patients can be correlated with the restoration of the normal state of cell-mediated immunity...
  88. ncbi request reprint Changing the endocrine dependence of breast cancer: data and hypotheses
    A Nicolini
    Unit of Oncology 2, Department of Oncology, University of Pisa, Via Roma 67, 56126, Pisa, Italy
    Curr Med Chem 21:1093-106. 2014
    ..Moreover, based on our recent reports, a new mechanistic interpretation of and a therapeutic approach for overcome hormone resistance are proposed. ..
  89. doi request reprint Relationship between triiodothyronine and proinflammatory cytokines in chronic heart failure
    V Lubrano
    G Monasterio Foundation, Pisa, Italy
    Biomed Pharmacother 64:165-9. 2010
    ..Cytokines and thyroid hormones are involved in the biochemical changes associated to heart failure (HF)...
  90. ncbi request reprint An in vitro study on the free radical scavenging capacity of ergothioneine: comparison with reduced glutathione, uric acid and trolox
    F Franzoni
    Dipartimento di Medicina Interna, Universita di Pisa, 67, Pisa, Italia
    Biomed Pharmacother 60:453-7. 2006
    ..The aim of this in vitro study was to assess the antioxidant activity of the natural product ergothioneine (EGT), a compound of plant origin, which is assimilated and conserved by mammals in erythrocytes, kidney, seminal fluid and liver...
  91. doi request reprint Plasma matrix metalloproteinase-9 better predicts outcome than N-terminal protype-B natriuretic peptide in patients with systolic heart failure and a high prevalence of coronary artery disease
    Frank Lloyd Dini
    Unità Operativa Malattie Cardiovascolari 2, Ospedale S Chiara, Azienda Ospedaliera Universitaria Pisana, Via Roma 67, 56126 Pisa, Italy
    Biomed Pharmacother 64:339-42. 2010
    ..46%, log-rank: 9.11, p=0.025). Our results demonstrated the value of plasma metalloproteinases-9 levels for prognostication of patients with systolic HF and a high prevalence of CAD...
  92. doi request reprint Thalidomide for improving cutaneous and pulmonary sarcoidosis in patients resistant or with contraindications to corticosteroids
    P Fazzi
    Respiratory Pathophysiology Section, Cardiothoracic and Vascular Department, University of Pisa, Pisa, Italy
    Biomed Pharmacother 66:300-7. 2012
    ..Limited data report thalidomide improves cutaneous sarcoidosis; no benefit has been reported for pulmonary localization...
  93. ncbi request reprint Antihypertensive effect of oral potassium aspartate supplementation in mild to moderate arterial hypertension
    F Franzoni
    Department of Internal Medicine, University of Pisa School of Medicine, Via Roma 67, 56126 Pisa, Italy
    Biomed Pharmacother 59:25-9. 2005
    ..Previous studies showed that potassium chloride (48-120 mmol/day) supplementation reduced arterial blood pressure (BP) in hypertensive patients...
  94. ncbi request reprint Diazepam administration prevents testosterone decrease and lipofuscin accumulation in testis of mouse exposed to chronic noise stress
    R Ruffoli
    Dipartimento di Morfologia Umana e Biologia Applicata, Medicina del Lavoro, Universita di Pisa, Pisa, Italy
    Andrologia 38:159-65. 2006
    ....
  95. ncbi request reprint Generalised wavelet analysis of cutaneous flowmotion during post-occlusive reactive hyperaemia in patients with peripheral arterial obstructive disease
    M Rossi
    Department of Internal Medicine, University of Pisa, Via Roma 67, 56100 Pisa, Italy
    Biomed Pharmacother 59:233-9. 2005
    ..However during reactive hyperaemia these mechanisms appear to be exhausted in accordance with the reduced vasoreactivity to Ach and SNP...
  96. ncbi request reprint Safety and effects on the lipid and C-reactive protein plasma concentration of the association of ezetimibe plus atorvastatin in renal transplant patients treated by cyclosporine-A: a pilot study
    V Panichi
    Department of Internal Medicine, Nephrology Section, University of Pisa, Italy
    Biomed Pharmacother 60:249-52. 2006
    ..4 mg/l (P < 0.05 for all). This pilot study suggests that the co-administration of E and A at 10 mg/day in renal transplant patients receiving CsA is well-tolerated and effective in reducing important cardiovascular risk factors...
  97. ncbi request reprint Nonpalpable thyroid carcinoma: clinical controversies on preoperative selection
    Angelo Carpi
    Department of Reproduction and Aging, University of Pisa, Pisa, Italy
    Am J Clin Oncol 26:232-5. 2003
    ..the natural history of a small thyroid carcinoma, as well as the accuracy of ultrasound and ultrasound-guided FNA in the specific institution...
  98. ncbi request reprint Large-needle aspiration biopsy for the preoperative selection of follicular adenoma diagnosed by fine-needle aspiration as a microfollicular nodule or suspected cancer
    Angelo Carpi
    Department of Reproduction and Aging, University of Pisa, Pisa, Italy
    Am J Clin Oncol 25:209-12. 2002
    ....
  99. ncbi request reprint Simvastatin and fluvastatin reduce interleukin-6 and interleukin-8 lipopolysaccharide (LPS) stimulated production by isolated human monocytes from chronic kidney disease patients
    Emanuela Mantuano
    Department of Internal Medicine, Nephrology Section, University of Pisa, Italy
    Biomed Pharmacother 61:360-5. 2007
    ..Statins reduce lipid levels, inflammation and cardiovascular events in patients with coronary artery disease; CKD patients show increased risk of cardiovascular and increased plasma levels of IL-6 and IL-8...
  100. ncbi request reprint Protective effect of L-propionylcarnitine in chronic cyclosporine-a induced nephrotoxicity
    Nicola Origlia
    Department of Neuroscience, Pharmacology Section, University of Pisa, Via Roma 55, 56126 Pisa, Italy
    Biomed Pharmacother 60:77-81. 2006
    ..In conclusion our study demonstrated for the first time in vivo that L-PC protects against functional and tissue damage associated to chronic CyA administration...
  101. ncbi request reprint Role of 18F-FDG-PET and PET/CT imaging in thyroid cancer
    Cristina Nanni
    Department of Radiology, Istituto Oncologico Veneto IOV, Padova, Italy
    Biomed Pharmacother 60:409-13. 2006
    ....