Giovanna Elisiana Carpagnano

Summary

Affiliation: University of Foggia
Country: Italy

Publications

  1. pmc Exhaled breath analysis and sleep
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Italy
    J Clin Sleep Med 7:S34-7. 2011
  2. ncbi request reprint Could exhaled ferritin and SOD be used as markers for lung cancer and prognosis prediction purposes?
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    Eur J Clin Invest 42:478-86. 2012
  3. ncbi request reprint Exhaled HPV Infection in Lung Cancer: Role of MA at 3p
    Giovanna E Carpagnano
    Department of Medical and Surgical Sciences, Institute of Respiratory Disease, University of Foggia, Foggia, Italy Electronic address
    Arch Med Res 45:383-7. 2014
  4. pmc Aspergillus spp. colonization in exhaled breath condensate of lung cancer patients from Puglia Region of Italy
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    BMC Pulm Med 14:22. 2014
  5. doi request reprint Aging and airway inflammation
    Giovanna Elisiana Carpagnano
    Department of Medical and Surgical Sciences, Institute of Respiratory Disease, Faculty of Medicine, University of Foggia, Foggia, Italy
    Aging Clin Exp Res 25:239-45. 2013
  6. doi request reprint Exhaled matrix metalloproteinase-9 in lung cancer
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, Univeristy of Foggia, Italy
    Rejuvenation Res 15:359-65. 2012
  7. doi request reprint Microsatellite alterations and cell-free DNA analysis: could they increase the cytology sensitivity in the diagnosis of malignant pleural effusion?
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    Rejuvenation Res 15:265-73. 2012
  8. ncbi request reprint 3p microsatellite signature in exhaled breath condensate and tumor tissue of patients with lung cancer
    Giovanna E Carpagnano
    Institute of Respiratory Disease, University of Foggia, Foggia, Italy
    Am J Respir Crit Care Med 177:337-41. 2008
  9. ncbi request reprint Exhaled inflammatory markers in aspirin-induced asthma syndrome
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    Am J Rhinol 21:542-7. 2007
  10. ncbi request reprint Exhaled pH, exhaled nitric oxide, and induced sputum cellularity in obese patients with obstructive sleep apnea syndrome
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    Transl Res 151:45-50. 2008

Collaborators

Detail Information

Publications44

  1. pmc Exhaled breath analysis and sleep
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Italy
    J Clin Sleep Med 7:S34-7. 2011
    ..In this review, we focus on exhaled breath analysis giving an update on its general aspects, its application in OSAS, and finally its actual clinical applicability and areas for future direction...
  2. ncbi request reprint Could exhaled ferritin and SOD be used as markers for lung cancer and prognosis prediction purposes?
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    Eur J Clin Invest 42:478-86. 2012
    ..The aim of this study was to evaluate the clinical value and the prognostic power of exhaled ferritin and exhaled SOD in patients with lung cancer...
  3. ncbi request reprint Exhaled HPV Infection in Lung Cancer: Role of MA at 3p
    Giovanna E Carpagnano
    Department of Medical and Surgical Sciences, Institute of Respiratory Disease, University of Foggia, Foggia, Italy Electronic address
    Arch Med Res 45:383-7. 2014
    ..In this study we aim to verify the role of MAs at 3p in non-small cell lung cancer (NSCLC) with HPV positivity and eventual correlation with sex, histotype, TNM stage and cigarette smoking...
  4. pmc Aspergillus spp. colonization in exhaled breath condensate of lung cancer patients from Puglia Region of Italy
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    BMC Pulm Med 14:22. 2014
    ....
  5. doi request reprint Aging and airway inflammation
    Giovanna Elisiana Carpagnano
    Department of Medical and Surgical Sciences, Institute of Respiratory Disease, Faculty of Medicine, University of Foggia, Foggia, Italy
    Aging Clin Exp Res 25:239-45. 2013
    ....
  6. doi request reprint Exhaled matrix metalloproteinase-9 in lung cancer
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, Univeristy of Foggia, Italy
    Rejuvenation Res 15:359-65. 2012
    ..Furthermore, increased MMP-9 has been commonly described in the serum and airways of non-small cell lung cancer (NSCLC) patients...
  7. doi request reprint Microsatellite alterations and cell-free DNA analysis: could they increase the cytology sensitivity in the diagnosis of malignant pleural effusion?
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    Rejuvenation Res 15:265-73. 2012
    ..The increase in cell-free DNA levels was also evaluated as a signal of probable malignancy...
  8. ncbi request reprint 3p microsatellite signature in exhaled breath condensate and tumor tissue of patients with lung cancer
    Giovanna E Carpagnano
    Institute of Respiratory Disease, University of Foggia, Foggia, Italy
    Am J Respir Crit Care Med 177:337-41. 2008
    ..Our group has recently demonstrated the possibility of studying microsatellite alterations (MAs) of 3p in the DNA of exhaled breath condensate (EBC) of patients with non-small cell lung cancer (NSCLC)...
  9. ncbi request reprint Exhaled inflammatory markers in aspirin-induced asthma syndrome
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    Am J Rhinol 21:542-7. 2007
    ....
  10. ncbi request reprint Exhaled pH, exhaled nitric oxide, and induced sputum cellularity in obese patients with obstructive sleep apnea syndrome
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    Transl Res 151:45-50. 2008
    ....
  11. ncbi request reprint IL-2, TNF-alpha, and leptin: local versus systemic concentrations in NSCLC patients
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Italy
    Oncol Res 16:375-81. 2007
    ..Their measure in the EBC could be proposed as noninvasive markers for an early detection of NSCLC and in the follow-up of this tumor...
  12. ncbi request reprint 3p microsatellite alterations in exhaled breath condensate from patients with non-small cell lung cancer
    Giovanna E Carpagnano
    Institute of Respiratory Disease, University of Foggia, Italy
    Am J Respir Crit Care Med 172:738-44. 2005
    ..Furthermore, MA information seems to be directly related with tobacco consumption, and is potentially applicable to screening and early diagnostic programs for patients with NSCLC...
  13. doi request reprint Prognostic value of exhaled microsatellite alterations at 3p in NSCLC patients
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Italy
    Lung Cancer 64:334-40. 2009
    ....
  14. ncbi request reprint [New biomolecular methodologies in diagnosis of lung cancer]
    Giovanna Elisiana Carpagnano
    Sezione di Malattie dell Apparato Respiratorio, Dipartimento di Scienze Mediche e del Lavoro, Universita, Foggia
    Recenti Prog Med 99:417-21. 2008
    ..Recently the DNA has been extracted from exhaled breath condensate, demonstrating the suitability of this sample for the study of genetic alterations and its potential role in screening programs of subjects at risk of lung cancer...
  15. doi request reprint Cigarette smoke and increased COX-2 and survivin levels in exhaled breath condensate of lung cancer patients: how hot is the link?
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    Lung Cancer 67:108-13. 2010
    ..Cycloxygenase and survivin, a COX-2 dependent factor of apoptosis resistance, seem to play a key role in this regard...
  16. ncbi request reprint Non-invasive study of airways inflammation in sleep apnea patients
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Italy
    Sleep Med Rev 15:317-26. 2011
    ..The aim of this review is to spread current knowledge on the non-invasive airway markers and on their potential clinical applications in OSAS...
  17. doi request reprint Systemic and airway inflammation in sleep apnea and obesity: the role of ICAM-1 and IL-8
    Giovanna E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    Transl Res 155:35-43. 2010
    ....
  18. ncbi request reprint Increased IL-6 and IL-4 in exhaled breath condensate of patients with nasal polyposis
    G E Carpagnano
    Section of Respiratory Diseases, Department of Occupational and Medical Sciences, Faculty of Medicine, University of Foggia
    Monaldi Arch Chest Dis 71:3-7. 2009
    ..The present study was designed to investigate IL-6 and IL-4 concentrations in nasal and oral exhaled breath condensate of patients with early and advanced NP, and following polypectomy...
  19. pmc Neutrophilic airways inflammation in lung cancer: the role of exhaled LTB-4 and IL-8
    Giovanna E Carpagnano
    Department of Medical and Occupational Sciences, Institute of Respiratory Disease, University of Foggia, Via degli Aviatori 1, Foggia 71100, Italy
    BMC Cancer 11:226. 2011
    ..The aim of this study was to give our contribution in this field by investigating LTB-4 and IL-8 in the breath condensate of NSCLC patients and verifying their role in cancer development and progression...
  20. doi request reprint The role of obstructive sleep apnea syndrome and obesity in determining leptin in the exhaled breath condensate
    G E Carpagnano
    Institute of Respiratory Diseases, University of Foggia, Foggia, Italy
    J Breath Res 4:036003. 2010
    ..Moreover, different mechanisms for determining leptin concentrations in the exhaled breath condensate and the blood are suggested...
  21. ncbi request reprint Airway inflammation in subjects with gastro-oesophageal reflux and gastro-oesophageal reflux-related asthma
    G E Carpagnano
    Institute of Respiratory Diseases, University of Foggia, Foggia, Italy
    J Intern Med 259:323-31. 2006
    ..Asthma and gastro-oesophageal reflux (GER) are both characterized by airway inflammation...
  22. pmc HPV in exhaled breath condensate of lung cancer patients
    G E Carpagnano
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, Faculty of Medicine, University of Foggia, Foggia, Italy
    Br J Cancer 105:1183-90. 2011
    ..The aim of this study was to investigate, for the first time to our knowledge, the presence of HPV in the exhaled breath condensate (EBC) of lung cancer patients...
  23. ncbi request reprint Use of exhaled breath condensate in the study of airway inflammation after hypertonic saline solution challenge
    Giovanna E Carpagnano
    Institute of Respiratory Disease, University of Foggia, Italy
    Chest 128:3159-66. 2005
    ..Hypertonic saline solution inhalation is suspected to produce airway inflammation...
  24. ncbi request reprint Exhaled markers in the monitoring of airways inflammation and its response to steroid's treatment in mild persistent asthma
    Giovanna E Carpagnano
    Institute of Respiratory Disease, University of Foggia, Italy
    Eur J Pharmacol 519:175-81. 2005
    ..65+/-0.16, P<0.001). We conclude that the measurement of exhaled IL-4 and pH in mild asthmatic subjects could be a useful way of monitoring their airway inflammation as well as their response to the treatment...
  25. ncbi request reprint Exhaled Interleukine-6 and 8-isoprostane in chronic obstructive pulmonary disease: effect of carbocysteine lysine salt monohydrate (SCMC-Lys)
    Giovanna E Carpagnano
    Institute of Respiratory Diseases, University of Medicine, Foggia, Italy
    Eur J Pharmacol 505:169-75. 2004
    ..Moreover, we showed an anti-inflammatory and antioxidant effect of short-term administration of SCMC-Lys in COPD, suggesting the importance of a further placebo-controlled study that should evaluate the effects of this drug...
  26. doi request reprint Menopausal asthma: a new biological phenotype?
    M P Foschino Barbaro
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    Allergy 65:1306-12. 2010
    ..The aim of the present study was to explore airway inflammation in menopausal asthmatic women in a noninvasive manner...
  27. pmc Supplementary oxygen in healthy subjects and those with COPD increases oxidative stress and airway inflammation
    G E Carpagnano
    Institute of Respiratory Diseases, University of Bari, Italy
    Thorax 59:1016-9. 2004
    ....
  28. ncbi request reprint Role of vasoactive intestinal Peptide in chronic obstructive pulmonary disease with pulmonary hypertension
    Donato Lacedonia
    1 Institute of Respiratory Diseases, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy
    Rejuvenation Res 17:33-9. 2014
    ..Conclusions: In the patients with COPD and PH and in particular in the group of OP PH, VIP is significantly increased, probably to correct the imbalance between vasoconstrictor and vasodilatator mediators. ..
  29. ncbi request reprint Inflammation, oxidative stress and systemic effects in mild chronic obstructive pulmonary disease
    M P Foschino Barbaro
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Italy
    Int J Immunopathol Pharmacol 20:753-63. 2007
    ....
  30. ncbi request reprint Evidence of lower oxidative stress in the air spaces of patients with reversible COPD
    G Serviddio
    Institute of Internal Medicine, Dipartimento di Scienze Mediche e del Lavoro, Universita di Foggia, Italy
    Int J Immunopathol Pharmacol 19:617-28. 2006
    ....
  31. ncbi request reprint Airways oxidative stress, lung function and cognitive impairment in aging
    C Gramiccioni
    Institute of Respiratory Disease, Department of Medical and Occupational Sciences, University of Foggia, Italy
    Monaldi Arch Chest Dis 73:5-11. 2010
    ....
  32. doi request reprint Nailfold capillaroscopic findings in systemic sclerosis related lung fibrosis and in idiopathic lung fibrosis
    Addolorata Corrado
    Rheumatology Clinic, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    Joint Bone Spine 77:570-4. 2010
    ..The aim of this study is to record the range of capillaroscopic anomalies in patients with idiopathic pulmonary fibrosis (IPF) and to detect the main differences compared to patients with pulmonary fibrosis associated to SSc (SSc-PF)...
  33. ncbi request reprint Exhaled NO and iNOS expression in sputum cells of healthy, obese and OSA subjects
    A Depalo
    Institute of Respiratory Diseases, Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy
    J Intern Med 263:70-8. 2008
    ....
  34. ncbi request reprint Increased inflammatory markers in the exhaled breath condensate of cigarette smokers
    G E Carpagnano
    Institute of Respiratory Disease, University of Bari, Italy
    Eur Respir J 21:589-93. 2003
    ..Exhaled interleukin-6 and leukotriene B4 levels may be useful noninvasive markers of airway inflammation in cigarette smokers...
  35. ncbi request reprint Interleukin-6 is increased in breath condensate of patients with non-small cell lung cancer
    G E Carpagnano
    Institute of Respiratory Diseases, University of Bari, Italy
    Int J Biol Markers 17:141-5. 2002
    ..9+/-0.3 pg/mL). These findings suggest that the measurement of IL-6 in the breath condensate of patients with NSCLC could be proposed as a parameter to take into account in early diagnosis and disease monitoring...
  36. ncbi request reprint Increased vitronectin and endothelin-1 in the breath condensate of patients with fibrosing lung disease
    G E Carpagnano
    Institute of Respiratory Diseases, University of Bari, Bari, Italy
    Respiration 70:154-60. 2003
    ..Better understanding of mediators involved in fibrosis may be useful for early diagnosis and in clinical monitoring of disease progression...
  37. ncbi request reprint Influence of subclinical hypothyroidism and T4 treatment on the prevalence and severity of obstructive sleep apnoea syndrome (OSAS)
    O Resta
    Institute of Respiratory Diseases, Department of Clinical Methodology and Medical Surgical Technologies, University of Bari, School of Medicine, Bari, Italy
    J Endocrinol Invest 28:893-8. 2005
    ....
  38. ncbi request reprint Endothelin-1 is increased in the breath condensate of patients with non-small-cell lung cancer
    G E Carpagnano
    Institute of Respiratory Disease, University of Bari, Bari, Italy
    Oncology 66:180-4. 2004
    ..This peptide has an important role also in non-small-cell lung cancer (NSCLC) where ET-1 expression has been found in 100% of cell lines...
  39. ncbi request reprint Increased leukotriene B4 and interleukin-6 in exhaled breath condensate in cystic fibrosis
    Giovanna E Carpagnano
    Department of Thoracic Medicine, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, United Kingdom
    Am J Respir Crit Care Med 167:1109-12. 2003
    ..3 +/- 0.7 and 6.9 +/- 0.5 pg/ml). These findings suggest that LTB4 and IL-6 levels are increased in exhaled breath condensate of patients with CF during exacerbation and could be used to monitor airway inflammation in these patients...
  40. ncbi request reprint Breath condensate pH in children with cystic fibrosis and asthma: a new noninvasive marker of airway inflammation?
    Giovanna E Carpagnano
    Department of Thoracic Medicine, National Heart and Lung Institute, Imperial College, London, UK
    Chest 125:2005-10. 2004
    ..The pH of exhaled breath condensate (EBC) is a promising marker. Although pH has been measured in the EBC of adults with inflammatory airway diseases, no study has measured this in children...
  41. ncbi request reprint Validity and reproducibility of morphologic analysis of nasal secretions obtained using ultrasonic nebulization of hypertonic solution
    Maria T Ventura
    Department of Internal Medicine, Immunology, and Infectious Diseases, University of Bari Medical School, Policlinico, Bari, Italy
    Ann Allergy Asthma Immunol 99:232-5. 2007
    ..Collection of nasal secretions is important for the evaluation of upper airways inflammation in many nasal disorders...
  42. ncbi request reprint 8-Isoprostane, a marker of oxidative stress, is increased in exhaled breath condensate of patients with obstructive sleep apnea after night and is reduced by continuous positive airway pressure therapy
    Giovanna E Carpagnano
    Institute of Respiratory Diseases, University of Bari, Bari, Italy
    Chest 124:1386-92. 2003
    ..Obstructive sleep apnea (OSA) is characterized by recurrent apnea during sleep that may compromise oxidative balance. Oxidative stress is increased in the blood and in the airways of OSA patients...
  43. ncbi request reprint Changes in sputum composition during 15 min of sputum induction in healthy subjects and patients with asthma and chronic obstructive pulmonary disease
    Olga Toungoussova
    Division of Pneumology, Fondazione Salvatore Maugeri, Care and Research Institute, Via per Mercadante Km 2, 70020 Cassano Delle Murge, Bari, Italy
    Respir Med 101:1543-8. 2007
    ..The use of sputum induction by inhalation of hypertonic saline to study the cellular and biochemical composition of the airways allows noninvasive sampling of the airways content and identification of markers of airways inflammation...
  44. ncbi request reprint Increased 8-isoprostane and interleukin-6 in breath condensate of obstructive sleep apnea patients
    Giovanna E Carpagnano
    Institute of Respiratory Diseases, University of Bari, Bari, Italy
    Chest 122:1162-7. 2002
    ..An increase of systemic biomarkers of inflammation and oxidative stress has been found in patients with OSA and obesity...