Monica Carmosino

Summary

Affiliation: University of Bari
Country: Italy

Publications

  1. pmc High-throughput fluorescent-based NKCC functional assay in adherent epithelial cells
    Monica Carmosino
    Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Via Amendola 165 A, Bari 70126, Italy
    BMC Cell Biol 14:16. 2013
  2. doi request reprint Identification of moesin as NKCC2-interacting protein and analysis of its functional role in the NKCC2 apical trafficking
    Monica Carmosino
    Department of Biosciences, Biotechnologies and Pharmacological Sciences, University of Bari, 70126 Bari, Italy
    Biol Cell 104:658-76. 2012
  3. doi request reprint Na+-K+-2Cl- cotransporter type 2 trafficking and activity: the role of interacting proteins
    Monica Carmosino
    Department of Biosciences, Biotechnologies and Pharmacological Sciences, University of Bari, Bari, Italy
    Biol Cell 104:201-12. 2012
  4. doi request reprint NKCC2 is activated in Milan hypertensive rats contributing to the maintenance of salt-sensitive hypertension
    Monica Carmosino
    General and Environmental Physiology, University of Bari, Bari, Italy
    Pflugers Arch 462:281-91. 2011
  5. ncbi request reprint Trafficking and phosphorylation dynamics of AQP4 in histamine-treated human gastric cells
    Monica Carmosino
    Department of General and Environmental Physiology, University of Bari, Via Amendola 165 A, 70126 Bari, Italy
    Biol Cell 99:25-36. 2007
  6. ncbi request reprint Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells
    Giuseppe Procino
    Department of General and Environmental Physiology, University of Bari, Bari, Italy
    Kidney Int 66:2245-55. 2004
  7. ncbi request reprint Bradykinin signaling counteracts cAMP-elicited aquaporin 2 translocation in renal cells
    Grazia Tamma
    Dipartimento di Fisiologia Generale e Ambientale, Via Amendola 165 A, Bari 70126, Italy
    J Am Soc Nephrol 16:2881-9. 2005
  8. ncbi request reprint Ser-256 phosphorylation dynamics of Aquaporin 2 during maturation from the ER to the vesicular compartment in renal cells
    Giuseppe Procino
    Dipartimento di Fisiologia Generale ed Ambientale, University of Bari, 70126 Bari, Italy
    FASEB J 17:1886-8. 2003
  9. ncbi request reprint Functional involvement of VAMP/synaptobrevin-2 in cAMP-stimulated aquaporin 2 translocation in renal collecting duct cells
    Sabine Gouraud
    Dipartimento di Fisiologia Generale ed Ambientale, University of Bari, Via Amendola 165 A, 70126 Bari, Italy
    J Cell Sci 115:3667-74. 2002
  10. doi request reprint Fluvastatin modulates renal water reabsorption in vivo through increased AQP2 availability at the apical plasma membrane of collecting duct cells
    Giuseppe Procino
    Department of General and Environmental Physiology, University of Bari, Bari, Italy
    Pflugers Arch 462:753-66. 2011

Collaborators

  • Grazia Tamma
  • Tae Hwan Kwon
  • Daniela Riccardi
  • Lorenzo A Pinna
  • Giuseppe Procino
  • Maria Svelto
  • Giovanna Valenti
  • Claudia Barbieri
  • Serena Milano
  • Sabine Gouraud
  • Antonia Laera
  • Roberta Mannucci
  • Maria C Nicoletti
  • Jurgen Wess
  • Jian H Li
  • Leonarda De Benedictis
  • Maria Grazia Mola
  • Yoskaly Lazo-Fernandez
  • Oriano Marin
  • Antonella Contri
  • Anna M Brunati
  • Soren Nielsen
  • Giuseppe Calamita
  • Walter Rosenthal
  • Ornella Rossetto

Detail Information

Publications12

  1. pmc High-throughput fluorescent-based NKCC functional assay in adherent epithelial cells
    Monica Carmosino
    Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Via Amendola 165 A, Bari 70126, Italy
    BMC Cell Biol 14:16. 2013
    ..Importantly, both NKCC isoforms are involved in the regulation of blood pressure and represent important potential drug targets for the treatment of hypertension...
  2. doi request reprint Identification of moesin as NKCC2-interacting protein and analysis of its functional role in the NKCC2 apical trafficking
    Monica Carmosino
    Department of Biosciences, Biotechnologies and Pharmacological Sciences, University of Bari, 70126 Bari, Italy
    Biol Cell 104:658-76. 2012
    ..The renal Na(+) -K(+) -2Cl(-) co-transporter (NKCC2) is expressed in kidney thick ascending limb cells, where it mediates NaCl re-absorption regulating body salt levels and blood pressure...
  3. doi request reprint Na+-K+-2Cl- cotransporter type 2 trafficking and activity: the role of interacting proteins
    Monica Carmosino
    Department of Biosciences, Biotechnologies and Pharmacological Sciences, University of Bari, Bari, Italy
    Biol Cell 104:201-12. 2012
    ....
  4. doi request reprint NKCC2 is activated in Milan hypertensive rats contributing to the maintenance of salt-sensitive hypertension
    Monica Carmosino
    General and Environmental Physiology, University of Bari, Bari, Italy
    Pflugers Arch 462:281-91. 2011
    ..The elevated plasma levels of aldosterone, found in MHS rats, may influence Na(+) balance through a SPAK-dependent regulation of NKCC2 accounting for the maintenance of the hypertensive state in MHS rats...
  5. ncbi request reprint Trafficking and phosphorylation dynamics of AQP4 in histamine-treated human gastric cells
    Monica Carmosino
    Department of General and Environmental Physiology, University of Bari, Via Amendola 165 A, 70126 Bari, Italy
    Biol Cell 99:25-36. 2007
    ..AQP4 (aquaporin 4) internalization and a concomitant decrease in the osmotic water permeability coefficient (Pf) after histamine exposure has been reported in AQP4-transfected gastric HGT1 cells...
  6. ncbi request reprint Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells
    Giuseppe Procino
    Department of General and Environmental Physiology, University of Bari, Bari, Italy
    Kidney Int 66:2245-55. 2004
    ....
  7. ncbi request reprint Bradykinin signaling counteracts cAMP-elicited aquaporin 2 translocation in renal cells
    Grazia Tamma
    Dipartimento di Fisiologia Generale e Ambientale, Via Amendola 165 A, Bari 70126, Italy
    J Am Soc Nephrol 16:2881-9. 2005
    ..These effects counteract physiologic vasopressin stimulation, which instead has an opposite effect on actin network organization through Rho inactivation...
  8. ncbi request reprint Ser-256 phosphorylation dynamics of Aquaporin 2 during maturation from the ER to the vesicular compartment in renal cells
    Giuseppe Procino
    Dipartimento di Fisiologia Generale ed Ambientale, University of Bari, 70126 Bari, Italy
    FASEB J 17:1886-8. 2003
    ..This result might explain the molecular basis of the dominant form of nephrogenic diabetes insipidus caused by the mutation E258K-AQP2, in which the phenotype is caused by an impaired routing of AQP2...
  9. ncbi request reprint Functional involvement of VAMP/synaptobrevin-2 in cAMP-stimulated aquaporin 2 translocation in renal collecting duct cells
    Sabine Gouraud
    Dipartimento di Fisiologia Generale ed Ambientale, University of Bari, Via Amendola 165 A, 70126 Bari, Italy
    J Cell Sci 115:3667-74. 2002
    ..These results represent the first evidence for the functional involvement of VAMP-2 in cAMP-induced AQP2 exocytosis in renal cells...
  10. doi request reprint Fluvastatin modulates renal water reabsorption in vivo through increased AQP2 availability at the apical plasma membrane of collecting duct cells
    Giuseppe Procino
    Department of General and Environmental Physiology, University of Bari, Bari, Italy
    Pflugers Arch 462:753-66. 2011
    ..In conclusion, these results strongly suggest that fluvastatin, or other drugs of the statin family, may prove useful in the therapy of XNDI...
  11. ncbi request reprint Minireview: aquaporin 2 trafficking
    Giovanna Valenti
    Department of General and Environmental Physiology, University of Bari, Italy
    Endocrinology 146:5063-70. 2005
    ..Together these findings underscore the importance of AQP2 in kidney pathophysiology...
  12. pmc Combination of secretin and fluvastatin ameliorates the polyuria associated with X-linked nephrogenic diabetes insipidus in mice
    Giuseppe Procino
    1 Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari, Italy 2 Centro di Eccellenza di Genomica in Campo Biomedico ed Agrario CEGBA, Bari, Italy
    Kidney Int 86:127-38. 2014
    ..Taken together, these findings open new perspectives for the pharmacological treatment of X-NDI. ..