L Canesi

Summary

Affiliation: University of Genoa
Country: Italy

Publications

  1. ncbi request reprint Immunomodulation by 17beta-estradiol in bivalve hemocytes
    Laura Canesi
    Istituto di Scienze Fisiologiche, Università Carlo Bo di Urbino, Italy
    Am J Physiol Regul Integr Comp Physiol 291:R664-73. 2006
  2. doi request reprint Effects of 3,5-diiodo-L-thyronine administration on the liver of high fat diet-fed rats
    Elena Grasselli
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, 16132 Genova, Italy
    Exp Biol Med (Maywood) 233:549-57. 2008
  3. doi request reprint Immunotoxicity of carbon black nanoparticles to blue mussel hemocytes
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Genova, Italy
    Environ Int 34:1114-9. 2008
  4. pmc Immunomodulation by different types of N-oxides in the hemocytes of the marine bivalve Mytilus galloprovincialis
    Caterina Ciacci
    Dipartimento di Scienze della Terra, della Vita e dell Ambiente DISUAN, Universita degli Studi di Urbino Carlo Bo, Urbino, Italy
    PLoS ONE 7:e36937. 2012
  5. pmc Effects of fruit and vegetable low molecular mass fractions on gene expression in gingival cells challenged with Prevotella intermedia and Actinomyces naeslundii
    Laura Canesi
    DIPTERIS, University of Genova, Corso Europa 26, 16132 Genova, Italy
    J Biomed Biotechnol 2011:230630. 2011
  6. doi request reprint Bivalve molluscs as a unique target group for nanoparticle toxicity
    Laura Canesi
    Dip Te Ris, Dipartimento per lo Studio del Territorio e delle sue Risorse, Universita di Genova, Corso Europa 26, 16132 Genova, Italy
    Mar Environ Res 76:16-21. 2012
  7. ncbi request reprint Immunomodulation of Mytilus hemocytes by individual estrogenic chemicals and environmentally relevant mixtures of estrogens: in vitro and in vivo studies
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, Genova 16132, Italy
    Aquat Toxicol 81:36-44. 2007
  8. ncbi request reprint Effects of Triclosan on Mytilus galloprovincialis hemocyte function and digestive gland enzyme activities: possible modes of action on non target organisms
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, 16132, Italy
    Comp Biochem Physiol C Toxicol Pharmacol 145:464-72. 2007
  9. ncbi request reprint Effects of 17beta-estradiol on mussel digestive gland
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, 16132 Genova, Italy
    Gen Comp Endocrinol 153:40-6. 2007
  10. doi request reprint Short-term effects of environmentally relevant concentrations of EDC mixtures on Mytilus galloprovincialis digestive gland
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, 16132 Genova, Italy
    Aquat Toxicol 87:272-9. 2008

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Immunomodulation by 17beta-estradiol in bivalve hemocytes
    Laura Canesi
    Istituto di Scienze Fisiologiche, Università Carlo Bo di Urbino, Italy
    Am J Physiol Regul Integr Comp Physiol 291:R664-73. 2006
    ..Our data indicate that the physiological role of E(2) in immunomodulation is conserved from invertebrates to mammals...
  2. doi request reprint Effects of 3,5-diiodo-L-thyronine administration on the liver of high fat diet-fed rats
    Elena Grasselli
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, 16132 Genova, Italy
    Exp Biol Med (Maywood) 233:549-57. 2008
    ..These data demonstrate that in the liver of HFD rats, T2 prevents both lipid accumulation and oxidative stress associated with increased fat metabolism...
  3. doi request reprint Immunotoxicity of carbon black nanoparticles to blue mussel hemocytes
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Genova, Italy
    Environ Int 34:1114-9. 2008
    ....
  4. pmc Immunomodulation by different types of N-oxides in the hemocytes of the marine bivalve Mytilus galloprovincialis
    Caterina Ciacci
    Dipartimento di Scienze della Terra, della Vita e dell Ambiente DISUAN, Universita degli Studi di Urbino Carlo Bo, Urbino, Italy
    PLoS ONE 7:e36937. 2012
    ....
  5. pmc Effects of fruit and vegetable low molecular mass fractions on gene expression in gingival cells challenged with Prevotella intermedia and Actinomyces naeslundii
    Laura Canesi
    DIPTERIS, University of Genova, Corso Europa 26, 16132 Genova, Italy
    J Biomed Biotechnol 2011:230630. 2011
    ..intermedia and A. naeslundii depending on the experimental conditions. Overall, the results suggested that LMM fractions could modulate the effects of bacteria associated with periodontal disease in gingival cells...
  6. doi request reprint Bivalve molluscs as a unique target group for nanoparticle toxicity
    Laura Canesi
    Dip Te Ris, Dipartimento per lo Studio del Territorio e delle sue Risorse, Universita di Genova, Corso Europa 26, 16132 Genova, Italy
    Mar Environ Res 76:16-21. 2012
    ..Overall, bivalves represent a particularly suitable model for investigating the effects and mechanisms of action underlying the potential toxicity of NPs in marine invertebrates...
  7. ncbi request reprint Immunomodulation of Mytilus hemocytes by individual estrogenic chemicals and environmentally relevant mixtures of estrogens: in vitro and in vivo studies
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, Genova 16132, Italy
    Aquat Toxicol 81:36-44. 2007
    ..The results indicate that Mytilus immune parameters can be suitably utilized to evaluate the estrogenic potential of environmental samples...
  8. ncbi request reprint Effects of Triclosan on Mytilus galloprovincialis hemocyte function and digestive gland enzyme activities: possible modes of action on non target organisms
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, 16132, Italy
    Comp Biochem Physiol C Toxicol Pharmacol 145:464-72. 2007
    ....
  9. ncbi request reprint Effects of 17beta-estradiol on mussel digestive gland
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, 16132 Genova, Italy
    Gen Comp Endocrinol 153:40-6. 2007
    ....
  10. doi request reprint Short-term effects of environmentally relevant concentrations of EDC mixtures on Mytilus galloprovincialis digestive gland
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, 16132 Genova, Italy
    Aquat Toxicol 87:272-9. 2008
    ..The results demonstrate that short-term exposure to environmentally relevant concentrations of EDC mixtures can interfere with the lysosomal function, redox-related enzyme activities and gene transcription of mussel digestive gland...
  11. ncbi request reprint Effects of blood lipid lowering pharmaceuticals (bezafibrate and gemfibrozil) on immune and digestive gland functions of the bivalve mollusc, Mytilus galloprovincialis
    L Canesi
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, 16132, Italy
    Chemosphere 69:994-1002. 2007
    ..The results indicate that in mussels environmental concentrations of hypolipidemic drugs can affect the immune function, as well as glycolysis, redox balance and peroxisomal function...
  12. doi request reprint In vitro effects of suspensions of selected nanoparticles (C60 fullerene, TiO2, SiO2) on Mytilus hemocytes
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, Genoa, Italy
    Aquat Toxicol 96:151-8. 2010
    ..The inflammatory effects of NPs were mediated by rapid activation of the stress-activated p38 MAPK. The results further support the hypothesis that in bivalves the immune system represents a significant target for NPs...
  13. ncbi request reprint Bisphenol-A alters gene expression and functional parameters in molluscan hepatopancreas
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, 16132 Genova, Italy
    Mol Cell Endocrinol 276:36-44. 2007
    ..Overall, these data indicate that BPA, at environmentally relevant concentrations, can have both estrogen-like and distinct effects in invertebrates like in vertebrates...
  14. doi request reprint Effects of vibrio challenge on digestive gland biomarkers and antioxidant gene expression in Mytilus galloprovincialis
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Italy
    Comp Biochem Physiol C Toxicol Pharmacol 152:399-406. 2010
    ..Moreover, the results support the hypothesis that host responses to bacteria may be taken into account when interpreting biomarker data in ecotoxicological studies...
  15. doi request reprint Biomarkers in Mytilus galloprovincialis exposed to suspensions of selected nanoparticles (Nano carbon black, C60 fullerene, Nano-TiO2, Nano-SiO2)
    L Canesi
    Dipartimento di Biologia, Universita di Genova, Corso Europa 26, 16132 Genova, Italy
    Aquat Toxicol 100:168-77. 2010
    ..Overall, these data further support the hypothesis that suspension feeding invertebrates represent a significant target for NPs in the aquatic environment...
  16. pmc The organophosphate Chlorpyrifos interferes with the responses to 17β-estradiol in the digestive gland of the marine mussel Mytilus galloprovincialis
    Laura Canesi
    Dipartimento di Biologia, Universita di Genova, Genova, Italy
    PLoS ONE 6:e19803. 2011
    ..In the digestive gland of the bivalve Mytilus galloprovincialis, a target tissue of both estrogens and pesticides, the possible effects of CHP on the responses to the natural estrogen 17β-estradiol (E(2)) were investigated...
  17. doi request reprint Immunomodulation in Mytilus galloprovincialis by non-toxic doses of hexavalent chromium
    C Ciacci
    DISUAN, Dipartimento di Scienze dell Uomo, dell Ambiente e della Natura, Università Carlo Bo di Urbino, Italy
    Fish Shellfish Immunol 31:1026-33. 2011
    ..Overall, the results indicate that exposure to non-toxic, environmentally relevant concentrations of Cr(VI) can modulate functional and molecular immune parameters in M. galloprovincialis...
  18. ncbi request reprint Growth factor-mediated signal transduction and redox balance in isolated digestive gland cells from Mytilus galloprovincialis Lam
    L Canesi
    Istituto di Scienze Fisiologiche, Universita di Urbino, Loc Crocicchia, Urbino PS, Italy
    Comp Biochem Physiol C Toxicol Pharmacol 125:355-63. 2000
    ..Overall, this study extends the hypothesis that cell signalling is intimately related to redox balance in marine invertebrate cells...
  19. ncbi request reprint 'In vivo' effects of Bisphenol A in Mytilus hemocytes: modulation of kinase-mediated signalling pathways
    Laura Canesi
    Istituto di Scienze Fisiologiche, Universita di Urbino Carlo Bo, Loc Crocicchia, 61029 Urbino PU, Italy
    Aquat Toxicol 71:73-84. 2005
    ..Overall, these data address the importance of investigating full range responses to EDCs in ecologically relevant marine invertebrate species...
  20. ncbi request reprint Rapid effects of 17beta-estradiol on cell signaling and function of Mytilus hemocytes
    Laura Canesi
    Istituto di Scienze Fisiologiche, Universita di Urbino Carlo Bo, Loc Crocicchia, 61029 Urbino PU, Italy
    Gen Comp Endocrinol 136:58-71. 2004
    ..Overall, our data support the hypothesis that the rapid effects and mechanisms of action of 17beta-estradiol are extremely conserved and that they may play a crucial role in endocrine-immune interactions in invertebrates...
  21. ncbi request reprint Effects of the brominated flame retardant tetrabromobisphenol-A (TBBPA) on cell signaling and function of Mytilus hemocytes: involvement of MAP kinases and protein kinase C
    Laura Canesi
    Istituto di Scienze Fisiologiche, Universita di Urbino Carlo Bo, Loc Crocicchia, 61029 Urbino PU, Italy
    Aquat Toxicol 75:277-87. 2005
    ....
  22. doi request reprint Aromatase mRNA expression in the brain of adult Xenopus laevis exposed to Lambro river water and endocrine disrupting compounds
    A Massari
    Department of Biology, University of Genoa, Italy
    Gen Comp Endocrinol 168:262-8. 2010
    ....
  23. doi request reprint Heavy metal and growth hormone pathways in metallothionein regulation in fish RTH-149 cell line
    Laura Vergani
    Department of Biology, University of Genova, Genova, Italy
    Comp Biochem Physiol C Toxicol Pharmacol 149:572-80. 2009
    ....
  24. doi request reprint Functional differential immune responses of Mytilus galloprovincialis to bacterial challenge
    Caterina Ciacci
    DISUAN, Dipartimento di Scienze dell Uomo, dell Ambiente e della Natura, Università Carlo Bo di Urbino, Italy
    Comp Biochem Physiol B Biochem Mol Biol 153:365-71. 2009
    ..lysodeikticus and V. anguillarum, respectively, but not with V. splendidus. The results demonstrate the existence of differential functional immune responses in M. galloprovincialis to different bacteria...
  25. ncbi request reprint Persistence of vibrios in marine bivalves: the role of interactions with haemolymph components
    Carla Pruzzo
    Dipartimento di Biologia, Universita di Genova, Genova, Italy
    Environ Microbiol 7:761-72. 2005
    ....
  26. doi request reprint Interactions between Mytilus galloprovincialis hemocytes and the bivalve pathogens Vibrio aestuarianus 01/032 and Vibrio splendidus LGP32
    T Balbi
    DISTAV, Dipartimento di Scienze della Terra, dell Ambiente e della Vita, Universita di Genova, Corso Europa 26, 16132 Genova, Italy
    Fish Shellfish Immunol 35:1906-15. 2013
    ..Although V.s. is considered not pathogenic to Mytilus, this vibrio strain can affect the lysosomal function at the cellular and tissue level, thus leading to stressful conditions...
  27. ncbi request reprint Immunoelectron microscope analysis of epidermal growth factor receptor (EGFR) in isolated Mytilus galloprovincialis (Lam.) digestive gland cells: evidence for ligand-induced changes in EGFR intracellular distribution
    L Canesi
    Istituto di Scienze Fisiologiche, Loc Crocicchia, Urbino, Italy
    J Exp Zool 286:690-8. 2000
    ....
  28. ncbi request reprint Bacterial killing by Mytilus hemocyte monolayers as a model for investigating the signaling pathways involved in mussel immune defence
    L Canesi
    Istituto di Scienze Fisiologiche, Universita di Urbino, PS, Italy
    Mar Environ Res 54:547-51. 2002
    ....
  29. ncbi request reprint Effects of tumour necrosis factor alpha (TNFalpha) on Mytilus haemocytes: role of stress-activated mitogen-activated protein kinases (MAPKs)
    Michele Betti
    Istituto di Scienze Fisiologiche, Universita di Urbino Carlo Bo, Loc Crocicchia, 61029 Urbino PU, Italy
    Biol Cell 98:233-44. 2006
    ..In the present study, the effects of heterologous TNFalpha (tumour necrosis factor alpha) on cell signalling and function in the haemocytes of the bivalve Mytilus galloprovincialis Lam. were investigated...
  30. ncbi request reprint Effects of PCB congeners on the immune function of Mytilus hemocytes: alterations of tyrosine kinase-mediated cell signaling
    Laura Canesi
    Facoltà di Scienze Ambientali, Istituto di Scienze Fisiologiche, Universita di Urbino, Loc Crocicchia, 61029 PU, Urbino, Italy
    Aquat Toxicol 63:293-306. 2003
    ....
  31. ncbi request reprint Tyrosine kinase-mediated cell signalling in the activation of Mytilus hemocytes: possible role of STAT-like proteins
    Laura Canesi
    Istituto di Scienze Fisiologiche, Universita di Urbino, Loc Crocicchia, Urbino, 61029 PU, Italy
    Biol Cell 95:603-13. 2003
    ....
  32. ncbi request reprint Environmental estrogens can affect the function of mussel hemocytes through rapid modulation of kinase pathways
    Laura Canesi
    Istituto di Scienze Fisiologiche, Universita di Urbino, Carlo Bo, Loc Crocicchia, 61029 Urbino, Italy
    Gen Comp Endocrinol 138:58-69. 2004
    ..Our data address to the importance of investigating full range responses to estrogenic chemicals and may help understanding their basic mechanisms of action in ecologically relevant invertebrate species...
  33. ncbi request reprint Interactions between Mytilus haemocytes and different strains of Escherichia coli and Vibrio cholerae O1 El Tor: role of kinase-mediated signalling
    Laura Canesi
    Istituto di Scienze Fisiologiche, Universita di Urbino Carlo Bo, Loc Crocicchia, Italy
    Cell Microbiol 7:667-74. 2005
    ..These data suggest that certain bacteria could evade the bactericidal activity of mussel haemocytes through disruption of the host signalling pathways...
  34. ncbi request reprint PAT protein mRNA expression in primary rat hepatocytes: Effects of exposure to fatty acids
    Elena Grasselli
    Department of Biology, University of Genova, Genova, Italy
    Int J Mol Med 25:505-12. 2010
    ..Up-regulation of TIP47 and OXPAT might represent an early response to excess lipids, while, in correspondence with a lipid overload, up-regulation of ADRP could address lipids towards storage...
  35. ncbi request reprint Signaling pathways involved in the physiological response of mussel hemocytes to bacterial challenge: the role of stress-activated p38 MAP kinases
    Laura Canesi
    Istituto di Scienze Fisiologiche, Universita di Urbino, Loc Crocicchia, 61029 PU, Urbino, Italy
    Dev Comp Immunol 26:325-34. 2002
    ..Interestingly, the PI3-kinase (phosphatidylinositol-3-OH-kinase) inhibitor, Wortmannin, reduced both p38 activation and bacterial killing, indicating a critical role also for this lipid kinase in the hemocyte immune response...
  36. ncbi request reprint Bacteria-hemocyte interactions and phagocytosis in marine bivalves
    Laura Canesi
    Institute of Physiological Sciences, University of Urbino, Italy
    Microsc Res Tech 57:469-76. 2002
    ....
  37. ncbi request reprint Application of a biomarker battery for the evaluation of the sublethal effects of pollutants in the earthworm Eisenia andrei
    Laura Gastaldi
    Dipartimento di Scienze dell Ambiente e della Vita, DISAV, Universita del Piemonte Orientale Amedeo Avogadro, 15100 Alessandria, Italy
    Comp Biochem Physiol C Toxicol Pharmacol 146:398-405. 2007
    ....
  38. pmc Role for mannose-sensitive hemagglutinin in promoting interactions between Vibrio cholerae El Tor and mussel hemolymph
    Massimiliano Zampini
    Istituto di Microbiologia e Scienze Biomediche, Universita Politecnica delle Marche, Ancona, Italy
    Appl Environ Microbiol 69:5711-5. 2003
    ..The results indicate that hemolymph-soluble factors are involved in interactions between hemocytes and mannose-sensitive adhesins...