Simona Candiani

Summary

Affiliation: University of Genoa
Country: Italy

Publications

  1. pmc A neurochemical map of the developing amphioxus nervous system
    Simona Candiani
    Dipartimento per lo Studio del Territorio e delle sue Risorse, Universita di Genova, Viale Benedetto XV, 5, 16132 Genoa, Italy
    BMC Neurosci 13:59. 2012
  2. doi request reprint Focus on miRNAs evolution: a perspective from amphioxus
    Simona Candiani
    Laboratorio di Neurobiologia dello Sviluppo, Universita di Genova, Italia
    Brief Funct Genomics 11:107-17. 2012
  3. doi request reprint Expression of the amphioxus Pit-1 gene (AmphiPOU1F1/Pit-1) exclusively in the developing preoral organ, a putative homolog of the vertebrate adenohypophysis
    Simona Candiani
    Dipartimento di Biologia, Universita di Genova, Viale Benedetto XV 5, 16132 Genova, Italy
    Brain Res Bull 75:324-30. 2008
  4. pmc A study of neural-related microRNAs in the developing amphioxus
    Simona Candiani
    University of Genoa, Department of Biology, Viale Benedetto XV 5, 16132 Genoa, Italy
    Evodevo 2:15. 2011
  5. pmc Characterization, developmental expression and evolutionary features of the huntingtin gene in the amphioxus Branchiostoma floridae
    Simona Candiani
    Department of Biology, University of Genoa, Viale Benedetto XV 5, 16132, Genoa, Italy
    BMC Dev Biol 7:127. 2007
  6. doi request reprint The cholinergic gene locus in amphioxus: molecular characterization and developmental expression patterns
    Simona Candiani
    Department of Biology, University of Genoa, Genoa, Italy
    Dev Dyn 237:1399-411. 2008
  7. pmc The synapsin gene family in basal chordates: evolutionary perspectives in metazoans
    Simona Candiani
    Department of Biology, University of Genoa, Viale Benedetto XV5, 16132 Genova, Italy
    BMC Evol Biol 10:32. 2010
  8. ncbi request reprint Developmental expression of glutamic acid decarboxylase and of gamma-aminobutyric acid type B receptors in the ascidian Ciona intestinalis
    Giuliana Zega
    Dipartimento di Biologia, University of Milan, 20133, Milano, Italy
    J Comp Neurol 506:489-505. 2008
  9. ncbi request reprint Ci-POU-IV expression identifies PNS neurons in embryos and larvae of the ascidian Ciona intestinalis
    Simona Candiani
    Dipartimento di Biologia, Universita di Genova, Viale Benedetto XV 5, 16132 Genoa, Italy
    Dev Genes Evol 215:41-5. 2005
  10. ncbi request reprint AmphiD1/beta, a dopamine D1/beta-adrenergic receptor from the amphioxus Branchiostoma floridae: evolutionary aspects of the catecholaminergic system during development
    Simona Candiani
    Dipartimentodi Biologia, Universita di Genova, Genova, Italy
    Dev Genes Evol 215:631-8. 2005

Collaborators

Detail Information

Publications29

  1. pmc A neurochemical map of the developing amphioxus nervous system
    Simona Candiani
    Dipartimento per lo Studio del Territorio e delle sue Risorse, Universita di Genova, Viale Benedetto XV, 5, 16132 Genoa, Italy
    BMC Neurosci 13:59. 2012
    ..To this end, we cloned genes encoding biosynthetic enzymes and/or transporters of the most common neurotransmitters and assayed their developmental expression in the embryo and early larva...
  2. doi request reprint Focus on miRNAs evolution: a perspective from amphioxus
    Simona Candiani
    Laboratorio di Neurobiologia dello Sviluppo, Universita di Genova, Italia
    Brief Funct Genomics 11:107-17. 2012
    ..The present article outlines and discusses the current status of miRNAs information on the basal chordate amphioxus and the evolution of miRNAs in metazoans...
  3. doi request reprint Expression of the amphioxus Pit-1 gene (AmphiPOU1F1/Pit-1) exclusively in the developing preoral organ, a putative homolog of the vertebrate adenohypophysis
    Simona Candiani
    Dipartimento di Biologia, Universita di Genova, Viale Benedetto XV 5, 16132 Genova, Italy
    Brain Res Bull 75:324-30. 2008
    ....
  4. pmc A study of neural-related microRNAs in the developing amphioxus
    Simona Candiani
    University of Genoa, Department of Biology, Viale Benedetto XV 5, 16132 Genoa, Italy
    Evodevo 2:15. 2011
    ..abstract:..
  5. pmc Characterization, developmental expression and evolutionary features of the huntingtin gene in the amphioxus Branchiostoma floridae
    Simona Candiani
    Department of Biology, University of Genoa, Viale Benedetto XV 5, 16132, Genoa, Italy
    BMC Dev Biol 7:127. 2007
    ..In the present paper the amphioxus general term must be referred to Branchiostoma floridae...
  6. doi request reprint The cholinergic gene locus in amphioxus: molecular characterization and developmental expression patterns
    Simona Candiani
    Department of Biology, University of Genoa, Genoa, Italy
    Dev Dyn 237:1399-411. 2008
    ..Their later expression is primarily in the anterior nerve cord in several types of motoneurons, some of the interneurons and in the receptor cells of the larval ocellus...
  7. pmc The synapsin gene family in basal chordates: evolutionary perspectives in metazoans
    Simona Candiani
    Department of Biology, University of Genoa, Viale Benedetto XV5, 16132 Genova, Italy
    BMC Evol Biol 10:32. 2010
    ..Therefore, studying homologous genes in basal chordates, devoid of genome duplication, could help to achieve a better understanding of the complex functions of these proteins...
  8. ncbi request reprint Developmental expression of glutamic acid decarboxylase and of gamma-aminobutyric acid type B receptors in the ascidian Ciona intestinalis
    Giuliana Zega
    Dipartimento di Biologia, University of Milan, 20133, Milano, Italy
    J Comp Neurol 506:489-505. 2008
    ..intestinalis nervous system and that it can signal through GABA(B) receptors both pre- and postsynaptically to modulate different sensory inputs and subsequent swimming activity...
  9. ncbi request reprint Ci-POU-IV expression identifies PNS neurons in embryos and larvae of the ascidian Ciona intestinalis
    Simona Candiani
    Dipartimento di Biologia, Universita di Genova, Viale Benedetto XV 5, 16132 Genoa, Italy
    Dev Genes Evol 215:41-5. 2005
    ..Therefore, the evolution of a complex sensory system seems to be under the control of a common genetic mechanism...
  10. ncbi request reprint AmphiD1/beta, a dopamine D1/beta-adrenergic receptor from the amphioxus Branchiostoma floridae: evolutionary aspects of the catecholaminergic system during development
    Simona Candiani
    Dipartimentodi Biologia, Universita di Genova, Genova, Italy
    Dev Genes Evol 215:631-8. 2005
    ..In conclusion, the identification of the AmphiD1/beta receptor provides further basis for understanding the evolutionary history of the dopaminergic system at the transition from invertebrates and vertebrates...
  11. ncbi request reprint Developmental expression of tryptophan hydroxylase gene in Ciona intestinalis
    Roberta Pennati
    Dipartimento di Biologia, Universita di Milano, Via Celoria 26, 20133 Milano, Italy
    Dev Genes Evol 217:307-13. 2007
    ..Moreover, we discussed the involvement of serotonin in the control of larval locomotory activity...
  12. ncbi request reprint Expression of AmphiPOU-IV in the developing neural tube and epidermal sensory neural precursors in amphioxus supports a conserved role of class IV POU genes in the sensory cells development
    Simona Candiani
    Department of Biology, University of Genoa, Viale Benedetto XV, 5, Genoa, 16132, Italy
    Dev Genes Evol 216:623-33. 2006
    ....
  13. pmc Expression of AmphiNaC, a new member of the amiloride-sensitive sodium channel related to degenerins and epithelial sodium channels in amphioxus
    Simona Candiani
    Department of Biology, University of Genoa, Genoa, Italy
    Int J Biol Sci 2:79-86. 2006
    ..The analysis of AmphiNaC gene expression pattern suggests that it might be involved in neurotransmission and sensory modulation...
  14. ncbi request reprint Cloning and developmental expression of AmphiBrn1/2/4, a POU III gene in amphioxus
    Simona Candiani
    Dipartimento di Biologia Sperimentale, Ambientale e Applicata, Universita di Genova, Viale Benedetto XV 5, Italy
    Mech Dev 116:231-4. 2002
    ..Transcripts are also detected in the primordium of gill slits, pharynx and left Hatschek's diverticulum...
  15. ncbi request reprint Cloning and developmental expression of amphioxus Dachschund
    Simona Candiani
    Dipartimento di Biologia Sperimentale, Ambientale e Applicata, Universita di Genova, Viale Benedetto XV 5, 16132 Genova, Italy
    Gene Expr Patterns 3:65-9. 2003
    ....
  16. doi request reprint New findings in ATP supply in rod outer segments: insights for retinopathies
    Daniela Calzia
    Department of Pharmacy DIFAR, Biochemistry and Physiology Lab, University of Genoa, Genova, Italy
    Biol Cell 105:345-58. 2013
    ..Here, we focussed our study on the whole OS that contains the cytosol and plasma membrane and disks as native flattened saccules, unlike spherical osmotically intact disks...
  17. doi request reprint Expression of the orphan nuclear receptor NR4A in a putative adenohypophyseal homologue of amphioxus
    Simona Candiani
    Department of Biology, University of Genoa, Genoa, Italy
    Ann N Y Acad Sci 1163:361-4. 2009
    ..Developmental expression analysis of AmphiNR4A showed transcripts limited to the putative adenohypophyseal homologue of amphioxus...
  18. ncbi request reprint Neurotoxic effect of the herbicide paraquat on ascidian larvae
    Giuliana Zega
    Dipartimento di Biologia, Universita di Milano, Via Celoria 26, 20133, Milano, Italy
    Environ Toxicol Pharmacol 29:24-31. 2010
    ..For its sensitivity to paraquat and its simple chordate body plan, ascidian larva is a promising animal model to further investigate the molecular mechanism of paraquat neurotoxicity...
  19. doi request reprint Extramitochondrial tricarboxylic acid cycle in retinal rod outer segments
    Isabella Panfoli
    Department of Biology, University of Genoa, Viale Benedetto XV, 5, 16132 Genova, Italy
    Biochimie 93:1565-75. 2011
    ..Data, suggestive of the exportability of the mitochondrial machinery for aerobic metabolism, may shed light on those retinal pathologies related to energy supply impairment in OS and to mutations in TCA enzymes...
  20. ncbi request reprint Nitric oxide-evoked cGMP production in Purkinje cells in rat cerebellum: an immunocytochemical and pharmacological study
    Manuela Marcoli
    Dipartimento di Medicina Sperimentale, Sezione di Farmacologia e Tossicologia, Universita di Genova, 16148 Genova, Italy
    Neurochem Int 49:683-90. 2006
    ..Such immunocytochemical localisation appears consistent with functional evidence for physiologically relevant glutamate-dependent cGMP production in Purkinje cells in rat cerebellar cortex...
  21. doi request reprint Pharmacological characterization of NMDA-like receptors in the single-celled organism Paramecium primaurelia
    Paola Ramoino
    Department of Earth, Environment and Life Sciences DISTAV, University of Genoa, Corso Europa 26, 16132 Genoa, Italy
    J Exp Biol 217:463-71. 2014
    ....
  22. pmc Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells
    Massimiliano Monticone
    IRCCS Azienda Ospedaliera Universitaria San Martino IST Istituto Nazionale per la Ricerca sul Cancro, Largo R, Benzi, 10, 16132 Genoa, Italy
    BMC Cancer 12:358. 2012
    ....
  23. doi request reprint Are rod outer segment ATP-ase and ATP-synthase activity expression of the same protein?
    Daniela Calzia
    DIFAR, Universita di Genova, Genoa, Italy
    Cell Mol Neurobiol 33:637-49. 2013
    ....
  24. pmc The amphioxus genome illuminates vertebrate origins and cephalochordate biology
    Linda Z Holland
    Marine Biology Research Division, Scripps Institution of Oceanography, La Jolla, California 92093 0202, USA
    Genome Res 18:1100-11. 2008
    ..Our results indicate that the amphioxus genome is elemental to an understanding of the biology and evolution of nonchordate deuterostomes, invertebrate chordates, and vertebrates...
  25. doi request reprint In vitro modulation of gamma amino butyric acid (GABA) receptor expression by bone marrow stromal cells
    Manuela Marcoli
    Dip Medicina Sperimentale, Sezione di Farmacologia e Tossicologia, Università degli Studi di, Genova, Italy
    Pharmacol Res 57:374-82. 2008
    ..Therefore, we suggest that BMSC can be converted into cells equipped with appropriate receptors coupled to transduction mechanisms, potentially responding to a specific neurotransmitter...
  26. ncbi request reprint Pax-Six-Eya-Dach network during amphioxus development: conservation in vitro but context specificity in vivo
    Zbynek Kozmik
    Institute of Molecular Genetics, Videnska 1083, 14220 Prague 4, Czech Republic
    Dev Biol 306:143-59. 2007
    ..g. in the control of mitosis, apoptosis, and cell/tissue motility)...
  27. ncbi request reprint Preliminary observations on the spawning conditions of the European amphioxus (Branchiostoma lanceolatum) in captivity
    Michael Fuentes
    Laboratoire Arago, UMR 7628, CNRS and Universite Pierre et Marie Curie, BP 44, F 66651 Banyuls sur Mer, France
    J Exp Zool B Mol Dev Evol 302:384-91. 2004
    ....
  28. ncbi request reprint Glycoconjugate profiles of the lancelet (Branchiostoma lanceolatum) ovary: a lectin histochemical study by laser confocal microscopy
    Francesca Del Buono
    University of Siena, Italy
    Zygote 12:251-5. 2004
    ..On the contrary, chemical removal of O-linked chains by mild alkaline hydrolysis abolished AIA and RCA reactivity but had no effect on ConA positivity...
  29. ncbi request reprint Insights into spawning behavior and development of the European amphioxus (Branchiostoma lanceolatum)
    Michael Fuentes
    Laboratoire Arago, UMR7628 CNRS, University Pierre and Marie Curie Paris6 Banyuls sur Mer, F 66650, France
    J Exp Zool B Mol Dev Evol 308:484-93. 2007
    ..These studies have important implications for amphioxus animal husbandry and for improving laboratory techniques to develop amphioxus as an experimental animal model...