Affiliation: University of Pisa
- Testai L, Marino A, Piano I, Brancaleone V, Tomita K, Di Cesare Mannelli L, et al. The novel H2S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoKATP channels and reduction of oxidative stress. Pharmacol Res. 2016;113:290-299 pubmed publisher..In conclusion, H2S-donors, and in particular isothiocyanate-based H2S-releasing drugs like 4CPI, can actually be considered a suitable pharmacological option in anti-ischemic therapy. ..