Research Topics
Genomes and GenesSpecies | G BussolatiSummaryAffiliation: University of Turin Country: Italy Publications
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Detail Information
Publications
Oxytocin and oxytocin receptors in cancer cells and proliferationP Cassoni
Department of Biomedical Sciences and Human Oncology, University of Torino, Torino, Italy
J Neuroendocrinol 16:362-4. 2004....
Assessment of necrosis and hypoxia in ductal carcinoma in situ of the breast: basis for a new classificationG Bussolati
Department of Biomedical Sciences and Oncology, University of Torino, Italy
Virchows Arch 437:360-4. 2000....
111In-labeled 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid-lys(8)-vasotocin: a new powerful radioligand for oxytocin receptor-expressing tumorsG Bussolati
Department of Biomedical Sciences and Human Oncology, University of Torino, Vai Santena 7, 10126 Torino, Italy
Cancer Res 61:4393-7. 2001..The present study opens new perspectives for imaging and, possibly, therapy of OTR-positive human tumors such as breast and endometrial carcinomas, neuroblastomas, and glioblastomas...
Classic and recent special stains used in differential diagnosis of endocrine tumorsG Bussolati
Department of Biomedical Sciences and Oncology, University of Turin, Via Santena 7, I 10126 Turin, Italy
Endocr Pathol 12:379-87. 2001....
Expression of somatostatin receptor types 2, 3 and 5 in biopsies and surgical specimens of human lung tumours. Correlation with preoperative octreotide scintigraphyM Papotti
Department of Biomedical Sciences and Oncology, University of Turin, Torino, Italy
Virchows Arch 439:787-97. 2001..IHC can therefore be usefully coupled to radionuclear investigations to better characterize the sst cellular location and subtype in lung tumors...
34betaE12 cytokeratin immunodetection in the differential diagnosis of neuroendocrine carcinomas of the breastM Papotti
Department of Biomedical Sciences and Oncology, University of Turin, Torino, Italy
Appl Immunohistochem Mol Morphol 9:229-33. 2001..HMW CK can be added to the list of markers useful in the differential diagnosis of NE from non-NE tumors...
Proper detection of the nuclear shape: ways and significanceG Bussolati
Department of Biomedical Sciences and Human Oncology, University of Torino, Italy
Rom J Morphol Embryol 49:435-9. 2008..Finally, the prognostic importance of detecting irregularities of the nuclear shape in breast carcinomas by immunofluorescence staining for nuclear proteins will be discussed...
Meta-analysis of non-sentinel node metastases associated with micrometastatic sentinel nodes in breast cancerG Cserni
Bacs Kiskun County Teaching Hospital, Kecskemet, Hungary
Br J Surg 91:1245-52. 2004..The need for further axillary treatment in patients with breast cancer with low-volume sentinel node (SN) involvement (micrometastases or smaller) is controversial...
Tissue arrays as fiducial markers for section alignment in 3-D reconstruction technologyG Bussolati
Department of Biomedical Sciences and Human Oncology, University of Turin, Turin, 10126, Italy
J Cell Mol Med 9:438-45. 2005..This original methodology of incorporating Tissue Arrays into paraffin blocks as fiducial markers for three-dimensional reconstruction has a potential impact on histology for research purposes and diagnostic applications...
A modified Trastuzumab antibody for the immunohistochemical detection of HER-2 overexpression in breast cancerG Bussolati
Department of Biomedical Sciences and Human Oncology, University of Turin, Torino, Italy
Br J Cancer 92:1261-7. 2005..Biotinylated Trastuzumab can thus be used for immunohistochemical detection of HER-2 overexpression in breast cancer, and has the potential to identify patients likely to benefit from Trastuzumab treatment...
Patients with advanced stage breast carcinoma immunoreactive to biotinylated Herceptin are most likely to benefit from trastuzumab-based therapy: an hypothesis-generating studyA Sapino
Dipartimento di Scienze Biomediche e Oncologia Umana, Universita di Torino, Torino, Italy
Ann Oncol 18:1963-8. 2007..We previously showed that BiotHER immunoreactivity is highly correlated with HER2 amplification and indicated that it could be associated with better clinical outcome in advanced breast cancer patients receiving trastuzumab...
[Histological sectioning of brush bristles allows an improved diagnosis of biliary tract lesions]S Asioli
Dipartimento di Scienze Biomediche e Oncologia, Universita degli Studi di Torino, Torino, Italy
Minerva Med 98:373-8. 2007..Small fragments of the mucosa, of inflammatory cell aggregates or of carcinomas are observed and the results are optimally fixed and allow a definitive histological diagnosis...
A new vision of tubular and tubulo-lobular carcinomas of the breast, as revealed by 3-D modellingC Marchio
Department of Biomedical Sciences and Human Oncology, University of Turin, Torino, Italy
Histopathology 48:556-62. 2006..To reveal architectural structure and growth patterns of tubular carcinomas (TC) and tubulo-lobular carcinomas (TLC) of the breast...
Which breast carcinomas need HER-2/neu gene study after immunohistochemical analysis? Results of combined use of antibodies against different c-erbB2 protein domainsA Sapino
Department of Biomedical Sciences and Human Oncology, University of Torino Medical School, Italy
Histopathology 43:354-62. 2003..Evaluation of HER2 gene amplification in breast cancers is a compelling, routine procedure. The aim of this work was to evaluate which breast carcinomas would really benefit from HER-2/neu gene analysis...
Improved radiotracing of oxytocin receptor-expressing tumours using the new [111In]-DOTA-Lys8-deamino-vasotocin analogueB Chini
CNR Institute of Neuroscience, Cellular and Molecular Pharmacology Section, Via Vanvitelli 32, 20129 Milano, Italy
Br J Cancer 89:930-6. 2003..These features makes radiolabelled DOTA-dLVT a very good candidate for the radiotargeting of OTR-expressing tumours...
Pathological work-up of sentinel lymph nodes in breast cancer. Review of current data to be considered for the formulation of guidelinesG Cserni
Department of Pathology, , , Hungary
Eur J Cancer 39:1654-67. 2003..e. approximately 2% of all patients initially staged by SN biopsy. The methods for the intraoperative and molecular assessment of SNs are also surveyed...
Ultrasonographically-guided fine-needle aspiration of axillary lymph nodes: role in breast cancer managementA Sapino
Department of Biomedical Sciences and Human Oncology, University of Turin, Italy
Br J Cancer 88:702-6. 2003..This presurgical protocol is reliable for screening patients with LN metastases that should proceed directly to axillary dissection or adjuvant chemotherapy, thus avoiding sentinel lymph node biopsy...
Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysisM Papotti
Department of Biomedical Sciences and Oncology, University of Turin, Via Santena 7, 10126 Turin, Italy
Virchows Arch 440:461-75. 2002..It is concluded that SSTRs 1-5 are heterogeneously expressed in GEP endocrine tumors and that IHC is a reliable tool to detect SSTR types 2, 3 and 5 in surgical and biopsy specimens...
A plasmin-derived hexapeptide from the carboxyl end of osteocalcin counteracts oxytocin-mediated growth inhibition [corrected] of osteosarcoma cellsJ F Novak
Department of Biology, Bucknell University, Lewisburg, Pennsylvania 17837, USA
Cancer Res 60:3470-6. 2000..Suggested plasminogen activator-OC-OTR/OT interactions may have an effect on the regulation of cell proliferation within the bone tissue as well as properties of the extracellular matrix surrounding the tumor foci in the bone...
Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breastC Marchio
The Breakthrough Breast Cancer Research Centre Institute of Cancer Research, London, UK
J Pathol 215:398-410. 2008..Our results demonstrate that MPCs have distinct histological features and molecular genetic profiles supporting the contention that they constitute a distinct pathological entity...
[On-site evaluation and triage for endoscopic ultrasound-guided fine needle aspiration cytology. The Turin experience]P Campisi
Dipartimento di Scienze Biomediche e Oncologia, Universita degli Studi di Torino, Torino, Italy
Minerva Med 98:395-400. 2007....
Guidelines on the standards for the training of specialised health professionals dealing with breast cancerL Cataliotti
University of Florence, Florence, Italy
Eur J Cancer 43:660-75. 2007..The aim of this paper is to contribute to the increase in the level of care in a breast unit, as the input of qualified health professionals increases the quality of breast cancer patient care...
Histology far away from Flatland: 3D roller-coasting into grade-dependent angiogenetic patterns in oligodendrogliomasP Cassoni
Department of Biomedical Sciences and Human Oncology, University of Turin, Turin, Italy
J Cell Mol Med 12:564-8. 2008..We use here surgical specimens derived from oligodendrogliomas as a model for a novel elucidative 3D reconstruction of the grade-dependent vascular arborisation in brain tumours...
Galectin-3 does not reliably distinguish benign from malignant thyroid neoplasmsA Bartolazzi
Histopathology 48:212-3. 2006
Extensive DNA fragmentation in oxyphilic cell lesions of the thyroidM Volante
Departments of Biomedical Sciences and Oncology, University of Turin, Torino, Italy
J Histochem Cytochem 49:1003-11. 2001..These findings are consistent with an extensive DNA fragmentation peculiar to oxyphilic cells, which is not directly related to apoptosis and whose origin and biological significance are presently unknown...
Prostatic duct carcinoma with combined prostatic duct adenocarcinoma and urothelial carcinoma features: report of a caseD Pacchioni
Department of Urologic Pathology, University of Turin, Italy
Int J Surg Pathol 12:293-7. 2004..The proliferation index was high (60%), and p53 was diffusely expressed (55%). The incidence and significance of PDC with combined features is discussed with reference to literature data...
Consistency of staining and reporting of oestrogen receptor immunocytochemistry within the European Union--an inter-laboratory studyC A Wells
Department of Histopathology, St Bartholomew s Hospital Medical School, West Smithfield, London, EC1A 7BE, United Kingdom
Virchows Arch 445:119-28. 2004..The Quick score method of receptor assessment may also have too many categories for good concordance, and grouping of these into fewer categories may remove some of the variation among laboratories...
Growth inhibition of DMBA-induced rat mammary carcinomas by UK 114S Racca
Department of Biological and Clinical Sciences, University of Turin, Italy
Virchows Arch 431:323-8. 1997..The mechanism of the tumour inhibitory activity of UK 114 is probably related to induction of immunosurveillance...
Is detection of endocrine cells in breast adenocarcinoma of diagnostic and clinical significance?A Sapino
Department of Biomedical Sciences and Human Oncology University of Torino, Torino, Italy
Histopathology 40:211-4. 2002
Prognostic significance of the expression of immunohistochemically detectable differentiation markers in laryngeal carcinomasG Cortesina
Clinica Otorinolaringoiatrica, , Italy
Tumori 75:478-82. 1989..This study indicates that the combined use of morphologic and biologic (immunohistochemical) criteria may constitute an independent parameter of primary importance in predicting the evolution of laryngeal carcinomas...
