Research Topics
| P BurraSummaryAffiliation: University of Padova Country: Italy Publications
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Publications
Combined liver-kidney transplantation in a 15-year-old boy with alpha1-antitrypsin deficiencyMassimiliano Loreno
Department of Surgical and Gastroenterological Sciences, University of Padua, Via Giustiniani 2, 35122 Padua, Italy
J Hepatol 36:565-8. 2002....
Sexual dysfunction after liver transplantationPatrizia Burra
Gastroenterology, Multivisceral Transplant Unit, Department of Surgical and Gastroenterological Sciences, University of Padua, Padua, Italy
Liver Transpl 15:S50-6. 2009..5. More detailed and comprehensive data are needed in the field of sexual function after transplantation, and new strategies are needed to support and inform patients on the waiting list and after liver transplantation...
Hepatitis CPatrizia Burra
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Semin Liver Dis 29:53-65. 2009..We must be prepared for the fact that increasing numbers of HCV-positive recipients with allografts failing due to recurrent HCV will be asking to be retransplanted-and we do not know yet how to respond to this request...
Influence of steroids on HCV recurrence after liver transplantation: A prospective studyMarco Vivarelli
Department of Surgery and Transplantation, University of Bologna, Italy
J Hepatol 47:793-8. 2007..To assess the effect of long-term maintenance of steroids on HCV recurrence after liver transplantation (LT), that is still controversial, a prospective multicentre trial was conducted at the centres of Bologna and Padua, Italy...
Quality of life following organ transplantationPatrizia Burra
Gastroenterology Section, Department of Surgical and Gastroenterological Sciences, Padua University, Padua, Italy
Transpl Int 20:397-409. 2007..g. sexual function, pregnancy, schooling, sport and work...
Liver transplantation for HBV-related cirrhosis in Europe: an ELTR study on evolution and outcomesPatrizia Burra
Multivisceral Transplant Unit, Department of Surgery, Oncology and Gastroenterology, Padova University Hospital, Padova, Italy
J Hepatol 58:287-96. 2013..HBV-related chronic liver disease is one of the most common indications for liver transplantation (LT) in Europe. The ELTR database was used to evaluate outcomes and evolution over 20 years (01/1988 and 12/2010)...
Systemic administration of a novel human umbilical cord mesenchymal stem cells population accelerates the resolution of acute liver injuryPatrizia Burra
Gastroenterology, Department of Surgical, Oncological and Gastroenterological Sciences, Padova University Hospital, Via Giustiniani 2, Padova, 35128, Italy
BMC Gastroenterol 12:88. 2012..We aimed to evaluate the therapeutic potential of mesenchymal stem cells from human umbilical cord (UCMSCs), a readily available source of mesenchymal stem cells, in the CCl4-induced acute liver injury model...
The adolescent and liver transplantationPatrizia Burra
Multivisceral Transplant Unit, Gastroenterology Section, Department of Surgical and Gastroenterological Sciences, Padova University Hospital, Padova, Italy
J Hepatol 56:714-22. 2012..Non-adherence is associated with a poor medical outcome. Both physical and psychosocial functioning is reportedly lower among young liver transplant recipients than in the general population...
A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinomaAndreas A Schnitzbauer
University Hospital Regensburg, Department of Surgery, Regensburg, Germany
BMC Cancer 10:190. 2010..Therefore, we designed a prospective RCT to determine if the mTOR inhibitor sirolimus can improve hepatocellular carcinoma (HCC)-free patient survival in liver transplant (LT) recipients with a pre-transplant diagnosis of HCC...
Donor livers with steatosis are safe to use in hepatitis C virus-positive recipientsPatrizia Burra
Gastroenterology Section, Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Liver Transpl 15:619-28. 2009..Steatotic grafts do not seem to exacerbate the progression of fibrosis in HCV+ recipients, nor do they seem to negatively affect 3-year patient survival...
Liver transplantation for alcoholic liver disease in Europe: a study from the ELTR (European Liver Transplant Registry)P Burra
Gastroenterology, Department of Surgical and Gastroenterological Sciences, University Hospital of Padova, Padova, Italy
Am J Transplant 10:138-48. 2010..Screening for de novo tumors and prevention of cardiovascular complications are essential to provide better long-term results...
Longitudinal prospective study on quality of life and psychological distress before and one year after liver transplantationP Burra
Department of Surgical and Gastroenterological Sciences, University of Padua, Padua, Italy
Acta Gastroenterol Belg 68:19-25. 2005..The impact of liver disease and medical complications on quality of life (QOL) and psychological distress before and after liver transplantation (LT) is a matter of growing interest...
Strategies for liver support: from stem cells to xenotransplantationPatrizia Burra
Department of Surgical and Gastroenterological Sciences, University Hospital, Padova, Italy
J Hepatol 41:1050-9. 2004
Factors influencing renal function after liver transplantation. Results from the MOST, an international observational studyP Burra
Gastroenterology, Department of Surgical and Gastroenterological Sciences, University Hospital Padova, Padova, Italy
Dig Liver Dis 41:350-6. 2009..Given organ shortage it should be essential to determine which patients will experience progressive and severe renal dysfunction after liver transplantation (LT)...
Torque Teno Virus: any pathological role in liver transplanted patients?Patrizia Burra
Gastroenterology Section, Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
Transpl Int 21:972-9. 2008..On the basis of our data, TTV does not seem to cause liver damage following LT, although larger studies with a long-term follow up are needed to confirm these findings...
HCV infection in haemodialysed patients: a role for serum IL-10 and TGF-beta1 in liver damage?P Burra
Gastroenterology Section, Department of Surgical and Gastroenterological Sciences, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
Dig Liver Dis 40:827-33. 2008..IL-10 and TGF-beta1 could play a role in this setting as, IL-10 down-regulates hepatic fibrosis, while TGF-beta1 is a pro-fibrotic cytokine...
Experimental hepatology applied to stem cellsP Burra
Department of Surgical and Gastroenterological Sciences, University of Padua, Italy
Dig Liver Dis 40:54-61. 2008..The fact that numerous specialties were represented helped the audience to understand the stem cell research area from different standpoints, and what research has achieved so far...
The concept of quality of life in organ transplantationP Burra
Gastroenterology Section, Department of Surgical and Gastroenterological Sciences, Padua University, and Gastroenterology Unit, Feltre, Italy
Transplant Proc 39:2285-7. 2007....
Antiviral therapy for hepatitis C virus recurrence following liver transplantation: long-term results from a single center experienceP Burra
Department of Surgical and Gastroenterological Sciences, University Hospital, Padova, Italy
Transplant Proc 38:1127-30. 2006..This study aimed to assess the safety and efficacy of alpha-interferon (IFN) plus ribavirin for recurrent HCV following liver transplantation...
Should donors and recipients be matched in liver transplantation?Patrizia Burra
Division of Gastroenterology, Department of Surgical and Gastroenterological Sciences, Padova University Hospital, Padova, Italy
J Hepatol 45:488-94. 2006
Liver transplantation in alcoholic patientsPatrizia Burra
Section of Gastroenterology, Liver Gastroenterology Transplantation, Department of Surgical and Gastroenterological Sciences, University Hospital, University of the Study, Padua, Italy
Transpl Int 18:491-8. 2005....
Does liver-disease aetiology have a role in cerebral blood-flow alterations in liver cirrhosis?P Burra
Gastroenterology and Surgery, Department of Surgical and Gastroenterological Sciences, University of Padua, Italy
Eur J Gastroenterol Hepatol 16:885-90. 2004..Studies using brain-imaging techniques have shown changes in regional blood flow (rCBF) in patients with liver cirrhosis. It remains unknown whether the aetiology of liver disease accounts for these changes...
Therapeutic application of stem cells in gastroenterology: an up-datePatrizia Burra
Department of Surgical and Gastroenterological Sciences, Gastroenterology Section, University of Padua, 35128 Padova, Italy
World J Gastroenterol 17:3870-80. 2011..Here, we report on the issues discussed, including liver and intestinal diseases that may benefit from stem cell therapy, the biology of hepatic and intestinal tissue repair, and stem cell usage in clinical trials...
Warm hepatic ischemia in pigs: effects of L-arginine and oligotide treatmentP Burra
Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Universita degli Studi di Padova, Italy
J Invest Surg 14:303-12. 2001..The increased plasma levels of nitric oxide a week after ischemia-reperfusion injury support the hypothesis that it has a role in preventing liver damage. The same beneficial effect was not confirmed for oligotide...
Frontal cerebral blood flow is impaired in patients with heart transplantationPatrizia Burra
Gastroenterology Section, Department of Surgical and Gastroenterological Sciences, University of Padua, Via Giustiniani 2, Italy
Transpl Int 15:459-62. 2002....
Occurrence of post-transplant lymphoproliferative disorders among over thousand adult recipients: any role for hepatitis C infection?Patrizia Burra
Department of Surgical and Gastroenterological Sciences, University of Padua, Padua Italy
Eur J Gastroenterol Hepatol 18:1065-70. 2006..Hepatitis C virus may induce clonal expansion of B-lymphocytes and has been associated with extrahepatic lymphoproliferative disorders...
Infections and organ transplantation: new challenges for prevention and treatment of hepatitis C virusP Burra
Multivisceral Transplant Unit, Gastroenterology, Padova University, Padova Italy
Transplant Proc 43:2455-6. 2011..Therefore, antiviral treatment appears to be recommended for patients infected with HCV. This article reviewed recent evidence on antiviral therapy for HCV-infected patients...
Sexual dysfunction in chronic liver disease: is liver transplantation an effective cure?Patrizia Burra
Department of Surgical and Gastroenterological Sciences, Multivisceral Transplant Unit, Gastroenterology, University of Padova, Padova, Italy
Transplantation 89:1425-9. 2010..Further studies on pathophysiology and risk factors in the field of sexual function after liver transplantation along with new strategies to support and inform patients on the waiting list and after surgery are needed...
Adherence in liver transplant recipientsPatrizia Burra
Gastroenterology, Multivisceral Transplant Unit, Department of Surgical and Gastroenterological Sciences, University of Padua, Padua, Italy
Liver Transpl 17:760-70. 2011..Patients have been split into 2 age groups (adults and children/adolescents) because the scale of the problem and the potential risk factors differ in the 2 groups...
Donor-Model for End-Stage Liver Disease and donor-recipient matching in liver transplantationA Vitale
Unità di Chirurgia Epatobiliare e Trapianto Epatico, Azienda Università di Padova, Padova, Italy
Transplant Proc 43:974-6. 2011..The aim of this study was to evaluate the prognostic ability of D-MELD among a cohort of Italian patients already selected for LT on the basis of a D-R matching philosophy...
Risk factors in liver retransplantation: a single-center experienceC Crivellin
Multivisceral Transplant Unit, Department of Surgical and Gastroenterological Sciences, University Hospital of Padua, Padua, Italy
Transplant Proc 43:1110-3. 2011..Forty percent of deaths after Re-OLT occurred among HCV(+) recipients, but for reasons unrelated to HCV infection...
HCV histological recurrence and survival following liver transplantation in patients with and without hepatocellular carcinomaE De Martin
Department of Surgical and Gastroenterological Sciences, Gastroenterology, Padova University, Padova, Italy
Transplant Proc 40:1974-5. 2008..HCV recurrence after LT is universal. This study evaluated HCV recurrence and survival in patients transplanted for HCV and HCC...
Fibrosis progression and the pros and cons of antiviral therapy for hepatitis C virus recurrence after liver transplantation: a reviewE De Martin
Gastroenterology, Multivisceral Transplant Unit, Department of Surgical and Gastroenterological Sciences, Padua University, Padua, Italy
Transplant Proc 42:2223-5. 2010..In conclusion, the donor- recipient match should be assessed to limit HCV recurrences and their severity; AT is recommended to reduce or reverse the progression of fibrosis...
Estimation of the harm to the waiting list as a crucial factor in the selection of patients with hepatocellular carcinoma for liver transplantationA Vitale
Unità di Chirurgia Epatobiliare e Trapianto Epatico, Azienda Università di Padova, Padova, Italy
Transplant Proc 42:1194-6. 2010..The aim of this study was to evaluate the minimum post-OLT survival threshold that would justify the selection of a patient with HCC for OLT...
Long-term medical and psycho-social evaluation of patients undergoing orthotopic liver transplantation for alcoholic liver diseaseP Burra
Gastroenterology Unit, University Hospital, Padua, Italy
Transpl Int 13:S174-8. 2000..A multidisciplinary approach evaluating medical and psycho-social variables before OLT and a close follow up after OLT are mandatory for ALD patients...
Histological features after liver transplantation in alcoholic cirrhoticsP Burra
Department of Surgical and Gastroenterological Sciences, University of Padova, University Hospital, Italy
J Hepatol 34:716-22. 2001..This study aims to evaluate the effect of alcohol recidivism on survival rates and histological parameters in patients transplanted for alcoholic cirrhosis, with and without hepatitis C virus (HCV) infection...
HBV and HCV infections in heart transplant recipientsS Fagiuoli
Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
J Heart Lung Transplant 20:718-24. 2001..The aim of the present study was to define the prevalence, clinical features, and natural history of HBV and HCV infections in a cohort of HTx recipients...
Balancing donor and recipient risk factors in liver transplantation: the value of D-MELD with particular reference to HCV recipientsA W Avolio
General Surgery and Transplantation Unit, Department of Surgery, A Gemelli Hospital, Catholic University, Rome, Italy
Am J Transplant 11:2724-36. 2011..The 5yrsPS<50% cutoff was identified only in HCV patients (D-MELD ≥ 1750). The innovative approach offered by D-MELD and covariates is helpful in predicting outcome after liver transplantation, especially in HCV recipients...
Algorithm for prioritization of patients on the waiting list for liver transplantationM Gambato
Gastroenterology, Department of Surgical and Gastroenterological Sciences, University of Padua, Padua, Italy
Transplant Proc 39:1855-6. 2007..Prioritization of patients on the waiting list (WL) for OLT is still a critical issue. Numerous models have been developed to predict mortality before and after OLT...
Combined liver and kidney transplantation: analysis of Padova experienceG Zanus
Department of Surgical and Gastroenterological Science, University of Padova, Padova, Italy
Transplant Proc 39:1933-5. 2007..The aim of this study was to evaluate our results with CLKT both in adult and pediatric patients...
Alcohol abuse and de novo tumors in liver transplantationG Zanus
Hepatobiliary and Liver Transplant Unit, Department of General Surgery and Organ Transplant, University of Padua, Padua, Italy
Transplant Proc 41:1310-2. 2009..Organ transplant recipients show an increased incidence of cancer ranging from 4% to 16% owing to several causes: immunosuppression, viral infection, individual predisposition, and so on...
Validation of the BCLC prognostic system in surgical hepatocellular cancer patientsA Vitale
Unità di Chirurgia Oncologica, Istituto Oncologico Veneto, IRCCS, Padova, Italy
Transplant Proc 41:1260-3. 2009..The aim of this study was to investigate the value of known prognostic systems in 400 Italian HCC patients treated with radical surgical therapies...
Sorafenib for the treatment of recurrent hepatocellular carcinoma after liver transplantation?A Vitale
Unità di Chirurgia Epatobiliare e Trapianto Epatico, Azienda Università di Padova, Padova, Italy
Transplant Proc 44:1989-91. 2012..There are scarce data on the use of sorafenib for the treatment of recurrent hepatocellular carcinoma (HCC) after orthotopic liver transplantation (OLT)...
Hepatitis C virus: from oxygen free radicals to hepatocellular carcinomaF Farinati
Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Sezione di Gastroenterologia, Policlinico Universitario, Universita di Padova, Padova, Italy
J Viral Hepat 14:821-9. 2007....
Neuropsychological and neurophysiological evaluation in cirrhotic patients with minimal hepatic encephalopathy undergoing liver transplantationM Senzolo
Gastroenterology, Department of Surgical and Gastroenterological Sciences, University-Hospital of Padua, Italy
Transplant Proc 37:1104-7. 2005....
Nonadherent behaviors after solid organ transplantationG Germani
Gastroenterology Department of Surgical and Gastroenterological Sciences, Padua University Hospital, Padova, Italy
Transplant Proc 43:318-23. 2011..The aim of this study was to assess, among patients who underwent solid organ transplantation, nonadherent behaviors (NAB) to immunosuppressive therapy, to correct lifestyle, and to general medical prescriptions...
Microwave thermal ablation for hepatocarcinoma: six liver transplantation casesG Zanus
General Surgery and Organ Transplantation, Hepatobiliary Surgery and Liver Transplant Unit, Azienda Università di Padova, Padova, Italy
Transplant Proc 43:1091-4. 2011..In conclusion, a MWA seemed to be a safe novel approach to treat HCC and could serve as a "bridge" to OLT and down-staging for patients with HCC...
Adjuvant chemotherapy for transplanted hepatocellular carcinoma patients: impact on survival or HCV recurrence timingM Bassanello
Clinica Chirurgica 1 and Liver Transplantation Unit, Department of Surgical and Gastroenterological Sciences, Padua University, P G Cevese University Hospital, Via Giustiniani 2, Padua 35128, Italy
Transplant Proc 35:2991-4. 2003..Liver transplantation (OLTx) represents a radical treatment for HCC and the underlying cirrhosis. Whether adjuvant chemotherapy is indicated in the postoperative period to prevent recurrence is controversial...
Changing attitude to organ donation and transplantation in university students during the years of medical school in ItalyP Burra
Department of Surgical and Gastroenterological Science University Hospital of Padua, Padua, Italy
Transplant Proc 37:547-50. 2005..In conclusion, medical student attitudes to organ donation and transplantation are highly positive, but do not improve during the first 3 years of Medical School. An educational program is therefore needed...
Bone metabolism and gonad function in male patients undergoing liver transplantation: a two-year longitudinal studyA Floreani
Department of Surgical and Gastroenterological Sciences, University of Padua, Italy
Osteoporos Int 12:749-54. 2001..Thus a high proportion of men with end-stage liver disease do have osteoporosis. After OLTx, an early recovery of gonad function is observed, followed by an increase in bone mass, which occurs from the sixth month onward...
Progression of hepatocellular carcinoma before liver transplantation: dropout or liver transplantation?A Vitale
Unità di Chirurgia Oncologica, Istituto Oncologico Veneto, IRCCS, Azienda Ospedaliera Universita di Padova, Padova, Italy
Transplant Proc 41:1264-7. 2009..The aim of this study was to show a correlation between adopted dropout criteria and dropout/intention-to-treat survival rates of WL HCC patients...
Functional and morphological graft monitoring after liver transplantationF P Russo
Department of Surgical and Gastroenterological Sciences, Gastroenterology Section, University of Padua, 35128, Padua, Italy
Clin Chim Acta 310:17-23. 2001..Liver biopsy is usually performed before the implantation of the graft to assess the viability of the liver and following liver transplantation, whenever clinical events warrant it or as part of a routine biopsy schedule...
Post-transplant lymphoproliferative disorders after heart or kidney transplantation at a single centre: presentation and response to treatmentS M L Aversa
Division of Medical Oncology, Istituto Oncologico Veneto, IRCCS, Padua, Italy
Acta Haematol 120:36-46. 2008..Moreover, 4 second neoplasms were observed in the chemotherapeutic group. In this study, we demonstrated that most PTLD need other treatment than RI and a weekly regimen is manageable and has a favourable impact on long-term survival...
Physiological and clinical implications of proANP(1-98) circulating levels in the perioperative phase of liver transplantationU Cillo
Department of Surgical and Gastroenterological Sciences, Clinica Chirurgica 1, University of Padua, Padua, Italy
Clin Chim Acta 310:39-48. 2001..03). CONCLUSIONS: ANP(1-98) values may represent a useful marker of hemodynamic derangements during and after OLTx. Further clinical correlations will need a larger patient basis...
Prospective validation of a new priority allocation model for liver transplant candidates: an interim analysisA Vitale
Unità di Chirurgia Epatobiliare e Trapianto Epatico, Dipartimento di Chirurgia Generale e Trapianti d Organo, Azienda Ospedaliera Universita di Padova, Padova, Italy
Transplant Proc 41:1092-5. 2009..We sought to prospectively validate a priority allocation model that is believed to achieve objectivity without penalizing dropout risk and post-OLT results...
Partial hepatectomy as first-line treatment for patients with hepatocellular carcinomaUmberto Cillo
Unità di chirurgia epatobiliare e trapianto di fegato, Dipartimento assistenziale di chirurgia generale e trapianti d organo, University of Padua, School of Medicine, Padova, Italy
J Surg Oncol 95:213-20. 2007..Partial hepatectomy (PH) and liver transplantation (LT) compete as first-line treatment for hepatocellular carcinoma (HCC). A prospectively collected database was retrospectively reviewed to establish when PH can compete with LT...
ABO blood group-related waiting list disparities in liver transplant candidates: effect of the MELD adoptionMichele Barone
Section of Gastroenterology, D E T O, University of Bari, Piazza G Cesare, Bari, Italy
Transplantation 85:844-9. 2008....
Microvascular autonomic dysfunction may justify false-positive stress myocardial perfusion imaging in patients with liver cirrhosis undergoing liver transplantationM Senzolo
Department of Surgical and Gastroenterological Sciences, University of Padua, Padua, Italy
Transplant Proc 40:1916-7. 2008..The aim of this study was to prospectively investigate the usefulness of an integrated cardiological approach in cirrhotic patients undergoing liver transplantation...
Prognostic evaluation of the donor risk index among a prospective cohort of Italian patients undergoing liver transplantationA Vitale
Unità di Chirurgia Oncologica, Istituto Oncologico Veneto, IRCCS, Padova, Italy
Transplant Proc 41:1096-8. 2009..The aim of this study was to prospectively evaluate the prognostic ability of DRI among a cohort of Italian patients undergoing OLT...
Long-term evaluation of cognitive function and cerebral metabolism in liver transplanted patientsM Senzolo
Department of Surgical and Gastroenterological Sciences, University Hospital of Padua, Padua, Italy
Transplant Proc 41:1295-6. 2009....
Bax inhibitor-1 down-regulation in the progression of chronic liver diseasesAndromachi Kotsafti
Department of Surgical and Gastroenterological Sciences, University of Padua, Padua, Italy
BMC Gastroenterol 10:35. 2010....
Comparison between nifedipine and carvedilol in the treatment of de novo arterial hypertension after liver transplantation: preliminary results of a controlled clinical trialA Galioto
Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy
Transplant Proc 37:1245-7. 2005..Two of the nine nonresponders to nifedipine responded to carvedilol. The efficacy of monotherapy was observed in 11 of 40 randomized patients (27.5%). Carvedilol monotherapy is as effective as nifedipine but far better tolerated...
Is osteoporosis a peculiar association with primary biliary cirrhosis?Annarosa Floreani
Div Gastroenterologia, Via Giustiniani, 2, Padova 35128, Italy
World J Gastroenterol 11:5347-50. 2005....
The critical issue of hepatocellular carcinoma prognostic classification: which is the best tool available?Umberto Cillo
Clinica Chirurgica I, Dipartimento di Scienze Chirurgiche e Gastroenterologiche, University of Padua, School of Medicine, Via Giustiniani 2, 35128 Padua, Italy
J Hepatol 40:124-31. 2004..We investigated the value of known prognostic systems in the particular setting of a surgically oriented Liver Unit where 187 HCC Italian patients were mainly treated with radical therapies (resection and percutaneous ablation)...
Successful pregnancy in a liver transplant recipient treated with lamivudine for de novo hepatitis B in the graftMassimiliano Loreno
Department of Surgical and Gastroenterological Sciences, University of Padua, Via Giustiniani 2, 35128, Padua, Italy
Transpl Int 17:730-4. 2005..The course of gestation was uneventful and caesarean section was performed after 36 weeks. The newborn infant was a healthy male weighing 3,080 g and measuring 50 cm...
Use of sorafenib in patients with hepatocellular carcinoma before liver transplantation: a cost-benefit analysis while awaiting data on sorafenib safetyAlessandro Vitale
Unità di Chirurgia Oncologica, Istituto Oncologico Veneto, IRCCS, Padova, Italy
Hepatology 51:165-73. 2010..CONCLUSION: Sorafenib neoadjuvant therapy is cost-effective by comparison with no therapy for T2-HCC patients waiting for LT, particularly for median times to LT under 6 months...
Response to therapy as a criterion for awarding priority to patients with hepatocellular carcinoma awaiting liver transplantationAlessandro Vitale
Unità di Chirurgia Oncologica, Istituto Oncologico Veneto, IRCCS, Padova, Italy
Ann Surg Oncol 17:2290-302. 2010..This study was designed to assess the effectiveness of a policy for prioritizing HCC patients according to their response to pre-LT therapy...
The survival benefit of liver transplantation in hepatocellular carcinoma patientsUmberto Cillo
Unità di Chirurgia Epatobiliare e Trapianto Epatico, Azienda Ospedaliera Universita di Padova, Via Giustiniani 2, 35128 Padova, Italy
Dig Liver Dis 42:642-9. 2010..There are no studies evaluating the survival benefit of liver transplantation over alternative therapies for patients with hepatocellular carcinoma...
Liver transplantation for the treatment of moderately or well-differentiated hepatocellular carcinomaUmberto Cillo
Clinica Chirurgica I, Dipartimento di Scienze Chirurgiche e Gastroenterlogiche, Italy
Ann Surg 239:150-9. 2004..To determine the long-term results of liver transplantation for well- or moderately differentiated hepatocellular carcinoma (HCC)...
People's attitude toward xenotransplantation: affective reactions and the influence of the evaluation contextEnrico Rubaltelli
Department of Developmental and Socialization Psychology, University of Padua, Via Venezia 8, Padua, Italy
Xenotransplantation 16:129-34. 2009..human vs. pig donors) are presented together allowing people to compare among them (joint evaluation) and two conditions in which people are presented with only one of the two alternatives and cannot compare them (separate evaluation)...
Transcatheter arterial chemoembolization (TACE) in hepatocellular carcinoma (HCC): the role of angiogenesis and invasivenessAdriana Sergio
Istituto Oncologico Veneto, Padova, Italy
Am J Gastroenterol 103:914-21. 2008....
A randomized study comparing ligation with propranolol for primary prophylaxis of variceal bleeding in candidates for liver transplantationLorenzo Norberto
Department of Surgical and Gastroenterological Sciences, 1st Surgical Clinic, Surgical Endoscopy Unit, University of Padova, Padova, Italy
Liver Transpl 13:1272-8. 2007..Our results suggest that banding should not be utilized as primary prophylaxis in transplant candidates who can be treated with BB...
CD105(+) cells from Wharton's jelly show in vitro and in vivo myogenic differentiative potentialMaria Teresa Conconi
Department of Pharmaceutical Sciences, Cittadella Hospital, University of Padua, I 35131 Padua, Italy
Int J Mol Med 18:1089-96. 2006..These observations provide the first demonstration that CD105(+)/CD31(-)/KDR(-) cells are able not only to differentiate in vivo towards the myogenic lineage, but also to contribute to the muscle regenerative process...
Strengthening acceptance for xenotransplantation: the case of attraction effectEnrico Rubaltelli
Department of Developmental and Socialization Psychology, University of Padova, Padova, Italy
Xenotransplantation 15:159-63. 2008....
Clinical significance of alpha-fetoprotein mRNA in blood of patients with hepatocellular carcinomaUmberto Cillo
Clinica Chirurgica I, Department of Surgical and Gastroenterological Sciences, University of Padua, School of Medicine, Via Giustiniani 2, Policlinico III Piano, 35128 Padova, Italy
Clin Chim Acta 347:129-38. 2004....
Protocol liver biopsies in long-term management of patients transplanted for hepatitis B-related liver diseaseStefano Targhetta
Department of Surgical and Gastroenterological Sciences, Gastroenterology Section, University Hospital, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
World J Gastroenterol 12:1706-12. 2006..CONCLUSION: Though protocol biopsies may enable the detection of graft dysfunction at an early stage, the risk of progression and the clinical significance of these findings remains to be determined...
Liver transplantation in Italy: current status. Study Group on Liver Transplantation of the Italian Association for the Study of the Liver (A.I.S.F.)P Burra
Chair of Gastroenterology, University of Padua, Italy
Dig Liver Dis 32:249-56. 2000..The multidisciplinary Study Group on Liver Transplantation of the Italian Association for the Study of the Liver (AISF) has collected information from all the Italian centres to ascertain the degree of consistency in their methods...
Dynamic tests to study liver functionP Burra
Gastroenterology Section, Department of Surgical and Gastroenterological Sciences, University of Padova, Italy
Eur Rev Med Pharmacol Sci 8:19-21. 2004..They are more complex to perform and more expensive than conventional biochemical tests, but superior in monitoring the degree of liver dysfunction...
New insights into the coagulopathy of liver disease and liver transplantationM Senzolo
Department of Surgical and Gastroenterological Sciences, University Hospital of Padua, Padua, Italy
World J Gastroenterol 12:7725-36. 2006..During liver transplantation haemorrage may occur due to the pre-existing hypocoagulable state, the collateral circulation caused by portal hypertension and increased fibrinolysis which occurs during this surgery...
Isoniazid-related fulminant hepatic failure in a child: assessment of the native liver's early regeneration after auxiliary partial orthotopic liver transplantationUmberto Cillo
Clinica Chirurgica no. 1, Department of Surgical and Gastroenterological Sciences, University of Padua School of Medicine, Via Giustiniani 2, Policlinico III Piano, 35128, Padua, Italy
Transpl Int 17:713-6. 2005..In fact, the histological picture in this particular case may suggest the potential for NL recovery after INH-related FHF...
Understanding of and attitudes to organ donation and transplantation: a survey among Italian university studentsDaniele Canova
Department of Surgical and Gastroenterological Sciences, Padua University, Padova, Italy
Clin Transplant 20:307-12. 2006..Italian university students have a very positive attitude and willingness to donate their own organs after death, with no differences emerging as regards type of university education...
Understanding of and attitude to xenotransplantation among Italian university students: impact of a 3-yr university courseDaniele Canova
Department of Surgical and Gastroenterological Sciences, Padua University, Padua, Italy
Xenotransplantation 13:264-71. 2006..Approval of xenotransplantation was much the same among fourth year males and females, whereas in the first year, male students had approved more than female students...
Understanding of and attitudes to xenotransplantation: a survey among Italian university studentsManuela De Bona
Department of Surgical and Gastroenterological Sciences, Padua University, Padua, Italy
Xenotransplantation 11:133-40. 2004..The choice of a science rather than an arts faculty at university was more strongly associated with a positive opinion on xenotransplantation...
Metabolic activity of rat hepatocytes cultured on homologous acellular matrix and transplanted into Gunn ratsSilvia Tomat
Department of Surgical and Gastroenterological Sciences, University of Padua, I-35121 Padua, Italy
Int J Mol Med 18:837-42. 2006..It is concluded that hepatocytes seeded on HAM and transplanted into Gunn rats are able to metabolize bilirubin for at least two months, without signs of rejection even in the absence of immunosuppressive therapy...
Acellular liver matrix improves the survival and functions of isolated rat hepatocytes cultured in vitroPatrizia Burra
Department of Surgical and Gastroenterological Sciences, Section of Gastroenterology, University of Padua, Via Gabelli 65, I-35121 Padua, Italy
Int J Mol Med 14:511-5. 2004..Taken together, these findings indicate that HAM strongly improves viability and functional activity of rat hepatocytes cultured in vitro...
Study of the microcirculation in hDAF transgenic rat livers xenoperfused with human bloodSilvia Tomat
Department of Surgical and Gastroenterological Sciences, University of Padua, Via Giustiniani 2, VI piano Monoblocco, Padua, Italy
Xenotransplantation 16:83-90. 2009....
Micronuclei and broken eggs in human liver carcinogenesisMaria Guido
Department of Diagnostic Medical Sciences and Special Therapies, Pathology Unit, Universita degli Studi di Padova, Italy
Anticancer Res 28:2507-11. 2008..MNi/BE formation may result in activation of the p53-mediated cell cycle checkpoint...
Neurologic complications after solid organ transplantationMarco Senzolo
Gastroenterology, Department of Surgical and Gastroenterological Sciences, University Hospital of Padua, Padua, Italy
Transpl Int 22:269-78. 2009....
Growth hormone/insulin-like growth factor 1 axis recovery after liver transplantation: a preliminary prospective studyMarco Bassanello
Clinica Chirurgica I, Dipartimento di Scienze Chirurgiche e Gastroenterologiche, University of Padua, School of Medicine, Padua, Italy
Liver Transpl 10:692-8. 2004..Such a quick, postoperative modulation of IGF-1 plasma level by the graft suggests that this hormone has the potential to become one of the early indicators of post-OLT liver function recovery...
Different neurological outcome of liver transplantation for Wilson's disease in two homozygotic twinsMarco Senzolo
Gastroenterology, Department of Surgical and Gastroenterological Sciences, University of Padua, Padua, Italy
Clin Neurol Neurosurg 109:71-5. 2007..The presence of neurological clinical manifestations in Wilson's disease should recommend caution indicating liver transplantation, because irreversible brain damage may exist...
Effect of penicillamine and zinc on iron metabolism in Wilson's diseaseValentina Medici
Department of Surgical and Gastroenterological Sciences, Section of Gastroenterology, University of Padua, Padua, Italy
Scand J Gastroenterol 42:1495-500. 2007..The purpose of this study was to assess the iron metabolism parameters, including hepatic iron concentration, in follow-up liver biopsies and serum, and urinary pro-hepcidin...
Risk of cancer following immunosuppression in organ transplant recipients and in HIV-positive individuals in southern EuropeDiego Serraino
Unita di Epidemiologia e Biostatistica, Centro di Riferimento Oncologico, Via F Gallini, 2, 33081 Aviano PN, Italy
Eur J Cancer 43:2117-23. 2007..8), and of borderline statistical significance in HIV-positive people (95% CI:0.9-2.8). Immune depression entails a two-fold increased overall risk of cancers, mainly related to cancers associated with a viral aetiology...
Double-blind comparison of hepatitis C histological recurrence Rate in HCV+ Liver transplant recipients given basiliximab + steroids or basiliximab + placebo, in addition to cyclosporine and azathioprineFranco Filipponi
Liver Transplantation Unit, University of Pisa, Hospital of Cisanello, Via Paradisa 2, 56100 Pisa, Italy
Transplantation 78:1488-95. 2004..Hepatitis C virus (HCV) recurrence in HCV+ liver transplant recipients is almost inevitable and may be promoted by immunosuppression. We compared the amount of liver damage with regard to usage of steroids and basiliximab...
Kaposi's sarcoma in transplant and HIV-infected patients: an epidemiologic study in Italy and FranceDiego Serraino
Dip Epidemiologia, INMI L Spallanzani, Rome, Italy
Transplantation 80:1699-704. 2005..A follow-up study was conducted in Italy and in France to compare the epidemiology of Kaposi's sarcoma (KS) between human immunodeficiency virus (HIV)-infected people and transplant recipients...
HLA-DRB1 donor-recipient mismatch affects the outcome of hepatitis C disease recurrence after liver transplantationLuca Saverio Belli
Department of Gastroenterology and Hepatology, Crespi Ospedale Niguarda, Milan, Italy
Gastroenterology 130:695-702. 2006....
A randomized study on Peg-interferon alfa-2a with or without ribavirin in liver transplant recipients with recurrent hepatitis CMario Angelico
Hepatology Unit, Tor Vergata University, Rome, Italy
J Hepatol 46:1009-17. 2007..We performed a randomized trial on pegylated interferon alfa-2a (Peg-IFNalpha) monotherapy vs Peg-IFNalpha and ribavirin in non-cirrhotic liver transplant recipients with recurrent hepatitis C...
Liver transplantation for HCV cirrhosis: improved survival in recent years and increased severity of recurrent disease in female recipients: results of a long term retrospective studyLuca S Belli
Hepatology and Abdominal Organ Transplantation Unit, Niguarda Hospital, Milan, Italy
Liver Transpl 13:733-40. 2007..The combination of a female recipient receiving an older graft emerged as a strong risk factor for a severe recurrence...
A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosisStuart J Forbes
Hepatology Section, Department of Medicine, Imperial College, London, England
Gastroenterology 126:955-63. 2004....
Incidence of second primary cancer in transplanted patientsEmanuela Taioli
University of Pittsburgh Cancer Institute, PA 15232, USA
Transplantation 81:982-5. 2006..However, the incidence of a second primary cancer in transplanted patients has never been studied, despite the fact that the presence of regular follow-ups and the increased survival of these patients make them a very attractive model...
Normal cortical regional cerebral blood flow justifies the normal neuropsychological performance in patients with cholestatic liver diseaseMarco Senzolo
Psychiatry Clin Neurosci 61:209-10. 2007
