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Genomes and Genes | M BuemiSummaryAffiliation: University of Messina Country: Italy Publications
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Publications
Statins in the prevention of cardiovascular events in patients with renal failureMichele Buemi
Cattedra di Nefrologia, Dipartimento di Medicina Interna, Universita di Messina, Via Salita Villa Contino, 98100 Messina, Italy
Cardiovasc Hematol Disord Drug Targets 7:7-13. 2007....
Real-time monitoring of breath ammonia during haemodialysis: use of ion mobility spectrometry (IMS) and cavity ring-down spectroscopy (CRDS) techniquesGiovanni Neri
Department of Industrial Chemistry and Materials Engineering, University of Messina, Messina, Italy
Nephrol Dial Transplant 27:2945-52. 2012....
Fibrosis, regeneration and cancer: what is the link?Valeria Cernaro
Division of Nephrology, Department of Internal Medicine, University of Messina, Messina, Italy
Nephrol Dial Transplant 27:21-7. 2012..The ideal approach would be to limit fibrosis and then organ function loss but without exposing the patient to risks of developing a tumour, starting from as early as the drugs prescribed...
Concentration of circulating endothelial progenitor cells (EPC) in normal pregnancy and in pregnant women with diabetes and hypertensionMichele Buemi
Department of Internal Medicine, Division of Hemathology, University of Messina, Messina, Italy
Am J Obstet Gynecol 196:68.e1-6. 2007....
Preeclampsia and cardiovascular risk: general characteristics, counseling and follow-upMichele Buemi
University of Messina, Messina Italy
J Nephrol 21:663-72. 2008..Preeclampsia is, moreover, a complex multispecialist entity, and the internist and/or the intensivist can be important allies along with the obstetrician in the management of this condition...
Dialysis-related genotoxicity: sister chromatid exchanges and DNA lesions in T and B lymphocytes of uremic patients. Genomic damage in patients on hemodiafiltrationM Buemi
Chair of Nephrology, Department of Internal Medicine, University of Messina, Messina, Italy
Blood Purif 24:569-74. 2006..The aim of our study was to verify the genomic damage in B- and T-lymphocyte subpopulations of uremic patients after a single hemodiafiltration session...
From the oxygen to the organ protection: erythropoietin as protagonist in internal medicineM Buemi
Chair of Nephrology, University of Messina, Italy
Cardiovasc Hematol Agents Med Chem 4:299-311. 2006..This review aims to stress the importance of the increasing interest in EPO applications and the necessity of further studies to gain a deeper knowledge of this hormone and its pleiotropic and complex actions...
Cardiorenal consequences of atherosclerosis and statins therapy: from the past to the futureMichele Buemi
Chair of Nephrology, Department of Internal Medicine, Messina, Italy
Curr Pharm Des 11:3973-84. 2005..Scientific progress has greatly improved our understanding of the pathogenic mechanisms underlying the progression of cardiovascular disease, and efforts in this discipline now appear more necessary than ever...
Statins in nephrotic syndrome: a new weapon against tissue injuryMichele Buemi
Department of Internal Medicine, University of Messina, Messina, Italy
Med Res Rev 25:587-609. 2005..In this study, we would like to provide scientific evidences for the pleiotropic effects of statins, which could be the starting point for the development of new therapeutical strategies in different clinical areas...
Kidney aging: from phenotype to geneticsMichele Buemi
Department of Internal Medicine, University of Messina, Messina, Italy
Rejuvenation Res 8:101-9. 2005..A better understanding of physiological renal aging could improve the clinical approach to this process and widen the therapeutic possibilities offered by transplantation...
The effect of two different protocols of potassium haemodiafiltration on QT dispersionMichele Buemi
Department of Internal Medicine, University of Messina, Italy
Nephrol Dial Transplant 20:1148-54. 2005....
Aquaporin-2 water channels in spontaneously hypertensive ratsMichele Buemi
Nephrology, Department of Internal Medicine, University of Messina, Messina, Italy
Am J Hypertens 17:1170-8. 2004..The PAVP appeared to be higher in OPC-treated rats from both strains. These findings suggest that AVP and the AQP2 are involved in the pathogenesis of hypertension in SHR...
Brain and cancer: the protective role of erythropoietinMichele Buemi
Chair of Nephrology, Department of Internal Medicine, University of Messina, Italy
Med Res Rev 25:245-59. 2005....
Effect of interleukin 8 and ICAM-1 on calcium-dependent outflow of K+ in erythrocytes from subjects with essential hypertensionM Buemi
Department of Internal Medicine, University of Messina, Via Salita Villa Contino 30 98100 Messina, Italy
Curr Med Res Opin 20:19-24. 2004....
Circadian rhythm of hydration in healthy subjects and uremic patients studied by bioelectrical impedance analysisMichele Buemi
Department of Internal Medicine, University of Messina, Messina, Italy
Nephron Physiol 106:p39-44. 2007..We aimed to evaluate by bioelectrical impedance analysis (BIA) whether body hydration status also follows a circadian rhythm in patients with impaired renal function...
Pulmonary hypertension and erythropoietinM Buemi
Department of Internal Medicine, University of Messina, Messina, Italy
Kidney Blood Press Res 30:248-52. 2007....
A new therapy for kidney injury: regenerationM Buemi
Department of Internal Medicine, Chair of Nephrology, University of Messina, Italy
Eur Rev Med Pharmacol Sci 15:111-21. 2011..In this field the kidney embryonic development phases can represent a fundamental study model to acquire information about the reparative mechanisms of the structure and function of this excretory organ...
[From oxygen to erythropoietin, as a protagonist of the skin-brain-kidney axis]Michele Buemi
Dipartimento di Medicina Interna, Universita degli Studi, Messina, Italy
G Ital Nefrol 27:609-15. 2010..Moreover, the results are not so unambiguous and further research on the pleiotropic effects of erythropoetin would be opportune...
Erythropoietin and the truths of scienceMichele Buemi
Division of Nephrology, Department of Internal Medicine, University of Messina, Via Salita Villa Contino 30, Messina, Italy
J Nephrol 24:564-8. 2011..Directions for future research hold promise, but only after we have fully understood the physiology of this potent growth factor...
[Erythropoietin: pleiotropic actions]Michele Buemi
Cattedra di Nefrologia, U O C di Terapia Subintensiva eTecniche Dialitiche, Dipartimento di Medicina Interna, Universita, Messina
Recenti Prog Med 101:253-67. 2010..Erythropoietin also acts in the endothelial proliferation of new vessels involving the tumor genesis, but it opens new frontiers to the employment of rHuEPO in the Regenerative Medicine...
Genomic damage in endothelial progenitor cells from uremic patients in hemodialysisMichele Buemi
Department of Internal Medicine, University of Messina, Messina Italy
J Nephrol 23:328-34. 2010..The aim of our study was to analyze the effects of a single HD session on the number of cells marked with CD34 (including sub-type cells known to be EPCs); we then evaluated the genomic damage in these cells using COMET assay...
Renal complications in oncohematologic patientsMichele Buemi
Department of Internal Medicine, University of Messina, Messina, Italy
J Investig Med 57:892-901. 2009..Further studies are awaited because a better knowledge of renal complications, which frequently occur in patients with oncohematologic diseases, would be conducive to making an early diagnosis and providing prompt therapy...
Down with the erythropoietin. Long live the erythropoietin!Michele Buemi
Chair of Nephrology, Department of Internal Medicine, University of Messina Messina, Italy
Curr Drug Targets 10:1028-32. 2009..Regenerative Medicine tries to develop therapeutic pathways through the stimulation of natural regenerative processes in humans...
The erythropoietin and regenerative medicine: a lesson from fishM Buemi
University of Messina, 98100 Messina, Italy
Eur J Clin Invest 39:993-9. 2009..Erythropoietin (EPO), the main haematopoietic growth factor for the proliferation and differentiation of erythroid progenitor cells, is also known for its angiogenic and regenerative properties...
Regenerative medicine: does Erythropoietin have a role?Michele Buemi
Department of Internal Medicine, University of Messina, Italy
Curr Pharm Des 15:2026-36. 2009..This is some of the experimental evidence which demonstrates that EPO can be in reason considered an important element of research of Regenerative Medicine and put in the network of drugs able to regenerate tissues and organs...
Neutrophil gelatinase-associated lipocalin as an early biomarker of nephropathy in diabetic patientsDavide Bolignano
Department of Internal Medicine, University of Messina, Messina, Italy
Kidney Blood Press Res 32:91-8. 2009..Renal tubulointerstitium plays an important role in the development and progression of diabetic nephropathy...
Arrhythmias and hemodialysis: role of potassium and new diagnostic toolsMichele Buemi
Department of Internal Medicine, University of Messina, Messina, Italy
Ren Fail 31:75-80. 2009..ECG and pneumographic impedance signals are acquired by the electrodes in the tissue, and the data are registered by a small computer and transmitted via GPRS or Bluetooth...
Aquaporin-2 (AQP2) urinary excretion and assumption of water with different mineral content in healthy subjectsMichele Buemi
Department of Internal Medicine, University of Messina, Messina, Italy
Ren Fail 29:567-72. 2007....
Flowing time on the peritoneal membraneMichele Buemi
Department of Internal Medicine and Institute of Human Anatomy, Via Salita Villa Contino 30, I-98100 Messina, Italy
Nephrol Dial Transplant 19:26-9. 2004
The pleiotropic effects of erythropoietin in the central nervous systemM Buemi
Unita di Terapia Subintensiva Metabolica e Dialitica, Dipartimento di Medicina Interna, Universita di Messina, Messina, Italy
J Neuropathol Exp Neurol 62:228-36. 2003....
Diet and arterial hypertension: is the sodium ion alone important?Michele Buemi
Chair of Nephrology, Department of Internal Medicine, University of Messina, Messina Italy
Med Res Rev 22:419-28. 2002..These changes in electrolyte levels can complicate treatments for arterial hypertension in some patients...
Effects of homocysteine on proliferation, necrosis, and apoptosis of vascular smooth muscle cells in culture and influence of folic acidM Buemi
Department of Internal Medicine, Faculty of Medicine, University of Messina, Via Salita Villa Contino, 30, 98100 Messina, Italy
Thromb Res 104:207-13. 2001..It is known that hyperhomocysteinemia is associated with an increased risk of vascular disease, yet little is known about the pathogenic mechanisms underlying the action of homocysteine (Hcy) itself...
Recombinant human erythropoietin (rHuEPO): more than just the correction of uremic anemiaMichele Buemi
Department of Internal Medicine, University of Messina, Italy
J Nephrol 15:97-103. 2002....
Cell proliferation/cell death balance in renal cell cultures after exposure to a static magnetic fieldM Buemi
Dipartimento di Medicina Interna, Facolta di Medicina e Chirurgia, Universita di Messina, Italy
Nephron 87:269-73. 2001..A gradual increase was observed in apoptotic, proliferating, and necrotic cells. Our findings suggest that the effect of exposure to MFs varies, depending on the cell type; MFs may also have a nephropathogenic effect...
Statins and progressive renal diseaseMichele Buemi
Department of Internal Medicine, University of Messina, Messina, Italy
Med Res Rev 22:76-84. 2002..Statins appear to have important potential in the treatment of progressive renal disease, although further studies are required to confirm this in humans...
Erythropoietin and the brain: from neurodevelopment to neuroprotectionM Buemi
Unita di Terapia Subintensiva Metabolica e Dialitica, Universita di Messina, Via Salita Villa Contino, 30 Pal Bianca 98100, Messina, Italy
Clin Sci (Lond) 103:275-82. 2002....
[Diverticular disease of the colon in peritoneal dialysis]M Buemi
Cattedra di Nefrologia, Dipartimento di Medicina Interna, Universita di Messina, Messina, Italy
G Ital Nefrol 19:540-4. 2002..In conclusion, diverticulosis alone is not a contraindication for peritoneal dialysis, but constitutes a risk factor for the continuation of this alternative treatment...
AQP1 in red blood cells of uremic patients during hemodialytic treatmentM Buemi
Department of Internal Medicine, University of Messina, Italy
Nephron 92:846-52. 2002..63, p < 0.05) between plasma AVP concentrations and plasma osmolality. The variations found in plasma osmolarity during hemodialysis, may induce AQP1 expression on the membrane of intact red blood cells...
Changes in plasma, erythrocyte, and platelet magnesium levels in normotensive and hypertensive obese subjects during oral glucose tolerance testF Corica
Department of Internal Medicine, School of Medicine, University of Messina, Italy
Am J Hypertens 12:128-36. 1999....
[Obesity and hypertension: the role of magnesium]F Corica
Dipartimento di Medicina Interna, Universita, Messina
Recenti Prog Med 89:169-76. 1998..In conclusion, in these studies has been confirmed the existence of a reduction of the intracellular magnesium concentrations, which is common in hypertensive and obese patients...
Reduced bcl-2 concentrations in hypertensive patients after lisinopril or nifedipine administrationM Buemi
Department of Internal Medicine, University of Messina, Italy
Am J Hypertens 12:73-5. 1999..Moreover, lisinopril and nifedipine appear to be capable of reducing bcl-2 concentrations, with potentially beneficial effects on vascular modifications in patients with hypertension...
Platelet magnesium depletion in normotensive and hypertensive obese subjects: the role of salt-regulating hormones and catecholaminesF Corica
Department of Internal Medicine, University of Messina, Italy
Magnes Res 12:287-96. 1999..Our results suggest that platelet magnesium depletion, together with disturbances of salt-regulating hormones and catecholamines, may be involved in the pathophysiology of cardiovascular complications from obesity...
Altered platelet magnesium and plasma and urinary soluble form of intercellular adhesion molecule I (sICAM-1) concentrations in insulin dependent diabetes mellitus (IDDM) patients with microalbuminuriaF Corica
Department of Internal Medicine, University of Messina, Italy
Magnes Res 9:307-12. 1996..64; P < 0.05) in the diabetics with microalbuminuria. It is concluded that the reduced intraplatelet magnesium content may contribute to the progression of the vascular complications in IDDM subjects with microalbuminuria...
Cardiovascular remodeling, apoptosis, and drugsM Buemi
Department of Internal Medicine, and Institute of Physiology, University of Messina, Italy
Am J Hypertens 13:450-4. 2000..This may be due to the direct effect of these drugs on the cell proliferation/apoptosis balance...
Urinary excretion of aquaporin-2 water channel during pregnancyM Buemi
Dept of Internal Medicine, University of Messina, Italy
Cell Physiol Biochem 11:203-8. 2001..The aim of the present study was to investigate the effect of normal pregnancy on urinary excretion of AQP2, a vasopressin sensitive water channel...
Leptin and norepinephrine plasma concentrations during glucose loading in normotensive and hypertensive obese womenF Corica
Department of Internal Medicine, University Hospital of Messina, Italy
Am J Hypertens 14:619-26. 2001..These findings suggest that leptin could be relevant in the regulation of blood pressure in obese women...
A case-by-case protocol of membranous nephropathy treatment with endovenous infusion of high doses of human immunoglobulinsF Floccari
Department of Internal Medicine, University of Messina, Messina, Italy
Nephron Clin Pract 108:c113-20. 2008..Secondly, we aimed to verify if some patients, judged as nonresponders to a classical protocol of IVIg therapy, could respond to a more prolonged treatment...
Is erythropoietin-induced hypertension a phenomenon due to the intracellular Ca++ mobilisation?M Buemi
Department of International Medicine, University of Messina, Italy
Int Angiol 13:75-7. 1994..The action exerted by rHuEPO could be due not an increased flow of the Ca++ from the extracellular department but to a mobilisation from Ca++ deposits...
From kidney to cardiovascular diseases: NGAL as a biomarker beyond the confines of nephrologyD Bolignano
Department of Internal Medicine, University of Messina, Messina, Italy
Eur J Clin Invest 40:273-6. 2010..It does not seem difficult that, in the next future, NGAL may become a new missing link between the kidney and the cardiovascular system...
[Therapy with vasopressin receptor antagonists: the aquaretics.]M Buemi
Cattedra di Nefrologia, Dipartimento di Medicina Interna, Universita degli Studi, Messina Italy
G Ital Nefrol 24:371-80. 2007..Furthermore, new applications may include the treatment of arterial hypertension, polycystic kidney disease, glaucoma and Meniere's syndrome...
Effects of the phytoestrogen genistein on cardiovascular risk factors in postmenopausal womenAlessandra Crisafulli
Department of Experimental Medicine and Pharmacology, University of Messina, Italy
Menopause 12:186-92. 2005..5%; P < 0.001), and serum SHBG was higher (63 +/- 3.8 nmol/L) compared with placebo (53 +/- 2.9 nmol/L; P < 0.05). CONCLUSION: Our study suggests that genistein may have a favorable effect on some cardiovascular markers...
Osteoprotegerin and bone mineral density in hemodiafiltration patientsA Crisafulli
Department of Experimental Medicine and Pharmacology, University of Messina, Italy
Ren Fail 27:531-9. 2005..As it may partly reflect a compensatory response to increased bone loss, this parameter might be helpful in the identification of patients with a marked reduction in trabecular BMD...
Neutrophil gelatinase-associated lipocalin (NGAL) and progression of chronic kidney diseaseDavide Bolignano
Department of Internal Medicine, University of Messina, Messima, Italy
Clin J Am Soc Nephrol 4:337-44. 2009..The authors aimed to evaluate whether neutrophil gelatinase-associated lipocalin (NGAL), a novel specific biomarker of acute kidney injury, could predict the progression of CKD...
Neutrophil gelatinase-associated lipocalin (NGAL): a new piece of the anemia puzzle?Davide Bolignano
Chair of Nephrology, Department of Internal Medicine, University of Messina, Messina, Italy
Med Sci Monit 16:RA131-5. 2010..From this point of view, NGAL may thus become an alternative therapeutic target for improving the treatment of secondary anemia related to these conditions...
Effects of haemodialysis on circulating endothelial progenitor cell countAlessio Sturiale
Department of Internal Medicine, University of Messina, Messina, Italy
Blood Purif 25:242-51. 2007....
Neutrophil gelatinase-associated lipocalin reflects the severity of renal impairment in subjects affected by chronic kidney diseaseDavide Bolignano
Department of Internal Medicine, University of Messina, Messina, Italy
Kidney Blood Press Res 31:255-8. 2008..The results confirm NGAL as an important biomarker in clinical nephrology, extending to CKD the pathophysiological role of this protein in tubular adaptations to renal damage...
[A brief "update" on renal effects of caffeine.]D Bolignano
Cattedra di Nefrologia, Dipartimento di Medicina Interna, Universita degli Studi, Messina Italy
G Ital Nefrol 24:188-94. 2007..While awaiting new, in-depth studies that will help to solve the debate, we can conclude that there is currently no evidence contraindicating the consumption of moderate quantities of caffeine by healthy subjects or kidney patients...
Environmental air pollution in an intensive care unit for nephrology and dialysisM Buemi
Department of Internal Medicine, University of Messina, Italy
J Nephrol 13:433-6. 2000..In none of the environments we were able to detect pathogens such as Aspergillus fumigatus, methycillin-resistant Staphylococci or toxin-producing fungi...
Erythropoietin protects against brain ischemic injury by inhibition of nitric oxide formationG Calapai
Institute of Pharmacology, School of Medicine, Torre Biologica 5o piano Policlinico Universitario, Via Consolare Valeria 49, I 98124, Messina, Italy
Eur J Pharmacol 401:349-56. 2000..These data suggest that in vivo recombinant human erythropoietin effects on brain ischemic injury could be due to inhibition of NO overproduction...
Neutrophil gelatinase-associated lipocalin (NGAL) in human neoplasias: a new protein enters the sceneDavide Bolignano
Department of Internal Medicine, University of Messina, Italy
Cancer Lett 288:10-6. 2010..Finally, in the field of clinical oncology, attention is currently focused on the potential use of NGAL levels in making an early diagnosis, establishing a prognosis and predicting response to different treatments...
Neutrophil gelatinase-associated lipocalin (NGAL) as a marker of kidney damageDavide Bolignano
Department of Internal Medicine, University of Messina, Messina, Italy
Am J Kidney Dis 52:595-605. 2008..For all these reasons, NGAL may become one of the most promising next-generation biomarkers in clinical nephrology and beyond...
Perioperative iloprost and endothelial progenitor cells in uremic patients with severe limb ischemia undergoing peripheral revascularizationGiuseppe Coppolino
Department of Internal Medicine, University of Messina, Italy
J Surg Res 157:e129-35. 2009..Iloprost treatment was able to amplify this mechanism validating recent findings (North TE et al., [31]). Adhesion molecules as markers of endothelial activation and vascular development confirmed this tendency...
Oxidative stress, sister chromatid exchanges and apoptosis in the pathogenesis of lymphocytopenia in ESRD patientsFrancesco Pernice
Department of Internal Medicine, University of Messina, Messina-Italy
J Nephrol 19:613-20. 2006..Our findings indicate that lymphopenia affecting end-stage renal disease (ESRD) patients may be strictly related to genomic damage exerted, at least in part, by TBARs, and to a dysregulation in programmed cell death...
QTc interval and QTc dispersion during haemodiafiltrationFulvio Floccari
Department of Internal Medicine, , Messina, Italy
Nephrology (Carlton) 9:335-40. 2004..Moreover, an increase in QTc dispersion occurred during the first hour of the session, and was negatively correlated with serum K+...
Chromosomal damage and atherosclerosis. A protective effect from simvastatinFranco Pernice
Department of Internal Medicine, University of Messina, Italy
Eur J Pharmacol 532:223-9. 2006..Statins may therefore have an anti-atherogenic action partly ascribable to their ability to provide protection against the development of atherosclerotic plaque...
Experimental models of acute renal failure and erythropoietin: what evidence of a direct effect?Alessio Sturiale
Department of Internal Medicine, Chair of Nephrology, University of Messina, Italy
Ren Fail 29:379-86. 2007..Very long-acting molecules or molecules with cyto-protective but no erythropoietic effect may represent useful tools in the study of the molecular mechanisms underlying EPO's action and may have a rapid and safe therapeutic application...
Effects of phytoestrogen genistein on cytogenetic biomarkers in postmenopausal women: 1 year randomized, placebo-controlled studyMarco Atteritano
Department of Internal Medicine, University of Messina, Italy
Eur J Pharmacol 589:22-6. 2008..The protective effect on genomic damage appears to be a particularly promising tool in reducing the risk of cancer...
Amelioration of spinal cord compressive injury by pharmacological preconditioning with erythropoietin and a nonerythropoietic erythropoietin derivativeGiovanni Grasso
Department of Neurosurgery, University of Palermo, Italy
J Neurosurg Spine 4:310-8. 2006....
Pathological and prognostic value of urinary neutrophil gelatinase-associated lipocalin in macroproteinuric patients with worsening renal functionDavide Bolignano
Department of Internal Medicine, University of Messina, Messina, Italy
Kidney Blood Press Res 31:274-9. 2008..Neutrophil gelatinase-associated lipocalin (NGAL) is a stress protein released by tubular cells which urinary excretion (uNGAL) increases in response to various stimuli...
Second trimester neutrophil gelatinase-associated lipocalin as a potential prediagnostic marker of preeclampsiaRosario D'Anna
Department of Obstetrics and Gynecology, University of Messina, Italy
Acta Obstet Gynecol Scand 87:1370-3. 2008..5%). The results suggest that serum NGAL might be involved in the pathophysiology of PE and could be a marker for this syndrome...
Erythropoietin suppresses peritoneal fibrosis in rat experimental modelStefania Mondello
Department of Internal Medicine, Messina University Hospital, School of Medicine, University of Messina, Italy
Eur J Pharmacol 604:138-49. 2009..Thus, EPO treatment reduces the degree of peritoneal fibrosis caused by CG. We propose that this evidence may help to clarify the potential therapeutic actions of EPO in patients with peritoneal fibrosis...
Thalidomide suppresses sclerosing encapsulating peritonitis in a rat experimental modelStefania Mondello
Department of Internal Medicine, Messina University Hospital, School of Medicine, University of Messina, Messina, Italy
Shock 32:332-9. 2009..Thus, thalidomide treatment reduces the degree of peritoneal fibrosis caused by CG. We propose that this evidence may help clarify the potential therapeutic actions of thalidomide in patients with peritoneal fibrosis...
Malnutrition in the elderly patient on dialysisAntonio Lacquaniti
Department of Internal Medicine, University of Messina, Messina, Italy
Ren Fail 31:239-45. 2009..In this patient category, it is therefore mandatory to ensure the daily supervision of nutritional status and early control when the first signs of malnutrition appear...
Erythropoietin and erythropoietin receptor expression after experimental spinal cord injury encourages therapy by exogenous erythropoietinGiovanni Grasso
Department of Neurosurgery, University of Messina, Messina, Italy
Neurosurgery 56:821-7; discussion 821-7. 2005....
Osteoprotegerin, IL-6, IL-1, TNF-alpha and TGF-beta concentrations during acetate-free biofiltrationMichele Buemi
Unita di Terapia Subintensiva Metabolica e Dialitica, Department of Internal Medicine, University of Messina, Messina, Italy
J Nephrol 18:148-53. 2005..It is our opinion that the lack of correlation between serum concentrations, observed in our study, could not exclude the presence of local interferences between OPG and the other cytokines...
Beneficial effects of systemic administration of recombinant human erythropoietin in rabbits subjected to subarachnoid hemorrhageGiovanni Grasso
Department of Neurosurgery, University of Messina, 98122 Messina, Italy
Proc Natl Acad Sci U S A 99:5627-31. 2002..05), ischemic neuronal damage (P < 0.001), and subsequent neurological deterioration (P < 0.05). These observations suggest that r-Hu-EPO may provide an effective treatment to reduce the post-SAH morbidity...
Assessment of human brain water content by cerebral bioelectrical impedance analysis: a new technique and its application to cerebral pathological conditionsGiovanni Grasso
Department of Neurosurgery, University of Messina, Messina, Italy
Neurosurgery 50:1064-72; discussion 1072-4. 2002..We present a quantitative, in vivo, bioelectrical impedance analysis (BIA) method and propose its use for the accurate assessment of brain water content among human subjects...
Does administration of recombinant human erythropoietin attenuate the increase of S-100 protein observed in cerebrospinal fluid after experimental subarachnoid hemorrhage?Giovanni Grasso
Department of Neurosurgery, University of Messina, Policlinico Universitario, Italy
J Neurosurg 96:565-70. 2002....
Endothelial progenitor cells: pathogenetic role and therapeutic perspectivesAlessandro Allegra
Division of Hematology, University of Messina, Messina, Italy
J Nephrol 22:463-75. 2009..Although the molecular mechanisms that promote the homing and recruitment of bone marrow-derived progenitor cells to remodeling tissues remain unclear the evidence that these cells promote tissue repair is strong...
Neutrophil gelatinase-associated lipocalin immunoexpression in renal tumors: correlation with histotype and histological gradeValeria Barresi
Departments of Human Pathology, University of Messina, Messina, Italy
Oncol Rep 24:305-10. 2010..Further studies are required to investigate the potential diagnostic utility of NGAL in the early diagnosis of metastatic progression of RCC...
Endothelin-1 concentrations in cord blood of neonates with meconium-stained amniotic fluidMarina Gemelli
Department of Pediatric Sciences, University of Messina, Messina, Italy
J Perinat Med 33:259-61. 2005..The effects of meconium-stained amniotic fluid (MSAF) on cord blood endothelin-1 (ET-1) concentrations have not been explored...
Raxofelast, a hydrophilic vitamin E-like antioxidant, stimulates wound healing in genetically diabetic miceM Galeano
Department of Plastic Surgery, University Hospital, University of Messina, ViaScite, 23 I-98124 Messina, Italy
Surgery 129:467-77. 2001....
Effects of hormonal replacement therapy on bone metabolism in young adults with beta-thalassemia majorA Lasco
Department of Internal Medicine, University of Messina, Italy
Osteoporos Int 12:570-5. 2001..Consequently, sex hormone replacement therapy represents an appropriate tool in the prevention and treatment of osteoporosis in thalassemics, probably together with bisphosphonates in cases with severely increased bone resorption...
Neutrophil gelatinase-associated lipocalin (NGAL) reflects iron status in haemodialysis patientsDavide Bolignano
Department of Internal Medicine, Chair of Nephrology, University of Messina, UOC Nefrologia e Dialisi, Catanzaro, Italy
Nephrol Dial Transplant 24:3398-403. 2009....
Recombinant human erythropoietin stimulates angiogenesis and healing of ischemic skin woundsMichele Buemi
Department of Internal Medicine, University of Messina, Messina, Italy
Shock 22:169-73. 2004..Our results suggest that erythropoietin may be an effective therapeutic approach in improving healing in ischemic skin wounds...
Aquaretic agents: what's beyond the treatment of hyponatremia?Davide Bolignano
Department of Internal Medicine, University of Messina, Italy
Curr Pharm Des 13:865-71. 2007..However, the future probably holds the promise of new and unexpected applications for this type of drug in the treatment of several conditions, including polycystic kidney and glomerular disease, glaucoma and Meniere's syndrome...
Neutrophil gelatinase-associated lipocalin in patients with autosomal-dominant polycystic kidney diseaseDavide Bolignano
Department of Internal Medicine, University of Messina, Messina, Italy
Am J Nephrol 27:373-8. 2007..Finally, our last finding that patients with HCG showed higher levels of NGAL suggests that this protein could be also involved in the cyst growth process, as previously reported about epithelial and tumoral expansion...
Increased plasma neutrophil gelatinase-associated lipocalin levels predict mortality in elderly patients with chronic heart failureDavide Bolignano
Department of Nephrology, University of Messina, Messina, Italy
Rejuvenation Res 12:7-14. 2009....
Pregnancy in uremic patients: an eventful journeyDavide Bolignano
Chair of Nephrology, Department of Internal Medicine, University of Messina, Messina, Italy
J Obstet Gynaecol Res 34:137-43. 2008....
Genistein effects on quantitative ultrasound parameters and bone mineral density in osteopenic postmenopausal womenM Atteritano
Department of Internal Medicine, University of Messina, Messina, Italy
Osteoporos Int 20:1947-54. 2009..We concluded that genistein prevented bone loss in the osteopenic postmenopausal women and improves QUS parameters at the calcaneus and phalanges...
Effects of alpha- and beta-adrenergic stimulation on free magnesium concentrations in platelets from healthy and obese individualsA Malara
Department of Internal Medicine, Policlinico Universitario, University of Messina, Italy
Magnes Res 14:263-72. 2001....
Management of patients after renal graft loss: an open question for nephrologistsGiuseppe Coppolino
Department of Internal Medicine, University of Messina, Italy
Ren Fail 28:203-10. 2006....
Circulating progenitor cells after cold pressor test in hypertensive and uremic patientsGiuseppe Coppolino
Department of Internal Medicine, University of Messina, Messina, Italy
Hypertens Res 31:717-24. 2008..CPT caused an increase in adhesion soluble molecules. Discrepancies in the numbers of HSCs and EPCs in CKD patients could suggest a specific impairment in blood vessel remodeling correlated with recognized endothelial dysfunction...
Erythropoietin prevents cognition impairment induced by transient brain ischemia in gerbilsMaria A Catania
Department of Clinical and Experimental Medicine and Pharmacology, Section of Pharmacology, School of Medicine, University of Messina, Via Consolare Valeria, Policlinico Universitario Torre Biologica No. 5 piano 98124 Messina, Italy
Eur J Pharmacol 437:147-50. 2002..These data indicate that recombinant human erythropoietin neuroprotective effects in brain ischemia are associated with the preservation of learning function...
Neurobiological model and quality of life in discovering personality of the uremic patientGiuseppe Coppolino
Department of Internal Medicine, University of Messina, Via Gazzi 9, Messina, Italy
J Nephrol 21:S139-45. 2008....
Experimental therapies in renal replacement: the effect of two different potassium acetate-free biofiltration protocols on striated muscle fibersGiuseppe Coppolino
Department of Internal Medicine, University of Messina, Messina, Italy
Ther Apher Dial 11:375-81. 2007..AFB(K) can minimize the negative effects of standard AFB treatment on neuromuscular excitability, most likely through a more gentle variation of potassium levels during dialysis...
Impaired antiviral activity of monocytes from patients on hemodiafiltrationAdriana Arena
Unit of Microbiology, Department of Surgical Sciences, University of Messina, Messina Italy
J Nephrol 20:560-7. 2007....
NGAL is a precocious marker of therapeutic responseValeria Cernaro
University of Messina, Department of Internal Medicine, Italy
Curr Pharm Des 17:844-9. 2011....
ICAM-1 in maternal serum and amniotic fluid as an early marker of preeclampsia and IUGRGiovanni Baviera
Departments of Gynecology and Internal Medicine, University of Messina, Messina, Italy
J Reprod Med 47:191-3. 2002..CONCLUSION: This study failed to demonstrate that ICAM-1 may be an early serum marker of preeclampsia or an amniotic fluid marker of IUGR...
Can peritoneal dialysis be used as a long term therapy for end stage renal disease?Michele Giannattasio
Struttura Complessa di Nefrologia e Dialisi, Azienda USL Bari 5 Putignano, Italy
Int Urol Nephrol 35:569-77. 2003....
Possible role of erythropoietin in the pathogenesis of chronic cor pulmonaleAlessandro Allegra
Nephrol Dial Transplant 20:2866-7. 2005
