Research Topics
| S BradamanteSummaryAffiliation: University of Milan Country: Italy Publications
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Detail Information
Publications
Glycogen turnover and anaplerosis in preconditioned rat heartsS Bradamante
CNR Centro Sintesi e Stereochimica di Speciali Sistemi Organici, University of Milan, Milan, Italy
Biochim Biophys Acta 1502:363-79. 2000..Our isotopomer data suggest that preconditioning accelerates metabolic and functional recovery during reperfusion by more efficient/active replenishment of the depleted Krebs cycle...
Production of lovastatin examined by an integrated approach based on chemometrics and DOSY-NMRSilvia Bradamante
CNR C S Sintesi e Stereochimica di Speciali Sistemi Organici, Milan, Italy
Biotechnol Bioeng 80:589-93. 2002..The approach has been validated in the case of lovastatin production from Aspergillus terreus...
Resveratrol provides late-phase cardioprotection by means of a nitric oxide- and adenosine-mediated mechanismSilvia Bradamante
CNR Istituto Scienze e Tecnologie Molecolari, University of Milan, Via Golgi 19, I 20133 Milan, Italy
Eur J Pharmacol 465:115-23. 2003..This suggests that long-term moderate resveratrol consumption could play an important role in late cardioprotective effects...
Does resveratrol induce pharmacological preconditioning?S Bradamante
CNR, University of Milan, Italy
Int J Tissue React 22:1-4. 2000..23 +/- 8.1% of controls; p < 0.05). The metabolic pattern following resveratrol infusion was similar to that produced by ischemic preconditioning, suggesting that an increase in adenosine availability is involved in cardioprotection...
Effects of gravity on proliferation and differentiation of adipose tissue-derived stem cellsS Versari
CNR Institute of Molecular Science and Technology, Milan, Italy
J Gravit Physiol 14:P127-8. 2007..The experiments lasted 7 or 14 days. We report data on AT-MSCs proliferation as DNA content, and on the expression of specific osteogenic markers (cbfa-1, alkaline phosphatase activity and Van Kossa staining)...
A NMR-compatible and reduced gravity simulation based (NRG) bioreactor for on-line monitoring cell culture metabolismS Bradamante
CNR ISTM, Istituto di Scienze e Tecnologie Molecolari, Milan, Italy
J Gravit Physiol 11:P191-2. 2004..The faster proliferation of endothelial cells cultured in the NRG bioreactor (doubling time : 28 +/- 1.7 vs. 43 +/- 5.6 h of the control grown in RWV) are attributed to different oxygenation conditions and medium wash out...
Induction of human endothelial cell growth by mildly oxidized low density lipoproteinJ A Maier
Dipartimento di Scienze e Technologie Biomediche, Ospedale San Raffaele, Milan, Italy
Atherosclerosis 123:115-21. 1996....
Cardiovascular protective effects of resveratrolSilvia Bradamante
CNR ISTM, Istituto di Scienze e Tecnologie Molecolari, Via Golgi 19, 20133 Milano, Italy
Cardiovasc Drug Rev 22:169-88. 2004..Although the reported biological data indicate that resveratrol is a highly promising cardiovascular protective agent, more studies are needed to establish its bioavailability and in vivo cardioprotective effects, particularly in humans...
Carnosine is a quencher of 4-hydroxy-nonenal: through what mechanism of reaction?Giancarlo Aldini
Istituto Chimico Farmaceutico Tossicologico, University of Milan, Viale Abruzzi 42, 20131 Milan, Italy
Biochem Biophys Res Commun 298:699-706. 2002..The biological role of carnosine as a quencher of alpha,beta-unsaturated aldehydes was verified by detecting carnosine-HNE reaction adducts in oxidized rat skeletal muscle homogenate...
Metal chelation aptitudes of bis(o-azaheteroaryl)methanes as tuned by heterocycle charge demandsAlessandro Abbotto
Department of Materials Science, University of Milano-Bicocca, Via Cozzi 53, I-20125, Milano, Italy
J Org Chem 67:5753-72. 2002..This key factor can therefore be used for the efficient design of new pi-deficient heteroaromatic nitrogen ligands in chelates of great potential in many synthetic, catalytic, and technological fields...
Simulated weightlessness in the design and exploitation of a NMR-compatible bioreactorSilvia Bradamante
CNR-ISTM, Istituto di Scienze e Tecnologie Molecolari, Via Golgi 19, I-20133 Milano, Italy. silvia.bradamante@ istm.cnr.it
Biotechnol Prog 20:1454-9. 2004..As a test study we focused on the proliferation of human umbilical vein endothelial cells (HUVEC) in terms of cell viability and organization of their cytoskeleton...
Alterations of the actin cytoskeleton and increased nitric oxide synthesis are common features in human primary endothelial cell response to changes in gravitySilvia Versari
CNR ISTM, Istituto di Scienze e Tecnologie Molecolari, Via Golgi, 19, Milano, Italy
Biochim Biophys Acta 1773:1645-52. 2007..Our results indicate that cytoskeletal alterations and increased nitric oxide production represent common denominators in endothelial responses to both hypogravity and hypergravity...
