Research Topics
Genomes and GenesSpecies | Mauro BozzolaSummaryAffiliation: University of Pavia Country: Italy Publications
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Publications
3-M syndrome associated with growth hormone deficiency: 18 year follow-up of a patientCristina Meazza
Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico San Matteo, Piazzale C, Golgi 2, Pavia 27100, Italy
Ital J Pediatr 39:21. 2013..Notwithstanding the early start of therapy and good compliance, his growth rate was always very low, except for the first two years of treatment and he achieved a final height of 132 cm (-6.42 SDS)...
Treatment adherence with the easypod™ growth hormone electronic auto-injector and patient acceptance: survey results from 824 children and their parentsMauro Bozzola
Paediatric Department, University of Pavia, IRCCS San Matteo Foundation, Pavia, Italy
BMC Endocr Disord 11:4. 2011..abstract:..- Role of adiponectin and leptin on body development in infants during the first year of lifeElena Bozzola
Paediatrics Department, University of Pavia, Fondazione IRCCS Policlinico San Matteo, Piazzale Golgi 2, Pavia, Italy
Ital J Pediatr 36:26. 2010..The aim of this study was to evaluate levels of adiponectin, leptin and insulin in appropriate (AGA) and small for gestational age (SGA) children during the 1st year of life and to correlate these with auxological parameters... 
[Fluticasone in the therapy of asthmatic children: short-term effects on growth]E Bozzola
Dipartimento di Scienze Pediatriche, Fondazione IRCCS San Matteo, Pavia, Italia
Minerva Pediatr 60:163-8. 2008..The aim of the study was to evaluate the influence of the therapy with spacer-administered inhaled corticosteroid on short-term auxological development in prepubertal children...- Unreliability of classic provocative tests for the diagnosis of growth hormone deficiencyA Mazzola
Pediatric Department, University of Pavia, Fondazione IRCCS San Matteo, 27100 Pavia, Italy
J Endocrinol Invest 31:159-62. 2008..The GHRH plus arginine test appears to be useful to identify false GH deficiency in children showing a blunted GH response to classic stimuli in contrast with normal growth rate... - Adult congenital adrenal hyperplasiaMauro Bozzola
Paediatric Department, University of Pavia, Pavia, Italy
Horm Res 68:154. 2007 - Low dose of insulin for assessment of growth hormone and cortisol release in short childrenMauro Bozzola
Pediatric Department, University of Pavia, Italy
J Pediatr Endocrinol Metab 18:815-8. 2005..62 +/- 2.89 years, we evaluated the efficacy of a test using only half the usual dose of insulin by comparing the results with those obtained during a classical arginine tolerance test, performed separately... - Growth hormone treatment in prepubertal children with celiac disease and growth hormone deficiencyDiletta Giovenale
Department of Pediatric Science, Universita degli Studi di Pavia, Fondazione IRCCS San Matteo, Pavia, Italy
J Pediatr Gastroenterol Nutr 45:433-7. 2007..To evaluate the growth response to growth hormone (GH) replacement therapy during a gluten-free diet in patients with celiac disease (CD) associated with GH deficiency (GHD)... - Effect of human recombinant growth hormone therapy on circulating levels of erythropoietin and granulocyte-colony stimulating factor in short childrenCristina Meazza
Paediatric Department, University of Pavia, Fondazione IRCCS San Matteo, Pavia, Italy
J Pediatr Endocrinol Metab 22:837-43. 2009..rhGH therapy influences Epo and G-CSF levels in short non-GHD children, while it shows no effects in GHD children... - Serum cytokine levels in GH-deficient children during substitutive GH therapySara Pagani
Dipartimento di Scienze Pediatriche, , Piazzale C Golgi 2, 27100 Pavia, Italy
Eur J Endocrinol 152:207-10. 2005..CONCLUSIONS: In vivo release of the pro-inflammatory cytokines IL-6 and TNF-alpha can be affected by hGH treatment in GHD children, suggesting a direct effect of GH on the immune function... - Response to long-term growth hormone therapy in short children with reduced GH bioactivityPaola Travaglino
Department of Pediatrics, University of Pavia, Pavia, Italy
Horm Res 66:189-94. 2006..CONCLUSIONS: Short rhGH therapy given to selected bioinactive GH children improve growth rate and might result in greater final adult height... - Short stature in children with coeliac diseaseCristina Meazza
Paediatric Department, University of Pavia, Fondazione IRCCS San Matteo, Italy
Pediatr Endocrinol Rev 6:457-63. 2009..These subjects show GH deficiency and could potentially benefit from recombinant human GH therapy. This review deals with the management of short stature and the evaluation of growth axis function in CD children... - Is BaF3 bioassay useful to identify patients with bioinactive growth hormone?Sara Pagani
Pediatric Department, University ofPavia, Italy
J Pediatr Endocrinol Metab 23:783-8. 2010..303 are indicative of a bioinactive GH molecule. This bioassay would recognize only extreme cases of GH bioinactivity, and it would not be a useful tool in the search for patients with altered forms of GH... - Effect of growth hormone (GH) on the immune systemCristina Meazza
Pediatric Department, University of Pavia, Piazzale C. Golgi 2, 27100 Pavia, Italy
Pediatr Endocrinol Rev 1:490-5. 2004..It is possible that in humans the GH produced locally in the immune system compensates for the lack of endocrine GH. In this review the main actions of GH on the immune system in vitro, in animal models and in humans are summarized... - The shortness of Pygmies is associated with severe under-expression of the growth hormone receptorMauro Bozzola
Pediatric Department, University of Pavia, Pavia, Italy
Mol Genet Metab 98:310-3. 2009..Our results, documenting a markedly reduced GHR gene expression in adult Pygmies, could contribute to elucidate the mechanisms involved in ISS in Caucasoid subjects... - Effect of growth hormone therapy on the proinflammatory cytokine profile in growth hormone-deficient childrenSara Pagani
Dipartimento di Scienze Pediatriche, , Piazzale C. Golgi 2, 27100 Pavia, Italy
Eur Cytokine Netw 16:65-9. 2005..It is reasonable to speculate that severe GH deficiency can cause alterations in the pro-inflammatory cytokine-induced immune response in humans, and that GH treatment can ameliorate this important immunological function... - The prevalence of growth hormone deficiency and celiac disease in short childrenDiletta Giovenale
Dipartimento di Scienze Pediatriche, , IRCCS Policlinico San Matteo, Pavia, Italia
Clin Med Res 4:180-3. 2006..CONCLUSIONS: GH secretion should be evaluated in celiac patients showing no catch-up growth after an appropriate period on a gluten-free diet in spite of reversion to seronegativity for EMA... - Common adipokine features of neonates and centenariansCristina Meazza
Dipartimento di Scienze Pediatriche e Patologia Umana ed Ereditaria, Universita di Pavia, Fondazione IRCCS San Matteo, Pavia, Italy
J Pediatr Endocrinol Metab 24:953-7. 2011..05) than elderly subjects. Centenarians, like AGA infants during the first year of life, show a favorable adipokine profile, suggesting that the metabolic condition at early age could affect the longevity of an individual... - Stimulating effect of growth hormone on cytokine release in childrenMauro Bozzola
Dipartimento di Scienze Pediatriche, Universita degli Studi di Pavia, IRCCS San Matteo, Piazzale le Golgi 2, 27100 Pavia, Italia
Eur J Endocrinol 149:397-401. 2003.... - The pygmy short stature enigmaCristina Meazza
Paediatrics Department, University of Pavia, Foundation IRCCS Policlinico San Matteo, Pavia, Italy
Pediatr Endocrinol Rev 8:394-9. 2011..These results provide a research target for future epigenetic investigations and suggest that the short stature of African Pygmies is probably determined by complex genetic systems... - Clinical management of short children with low serum immunoglobulin but no immunodeficiency featuresCristina Meazza
Pediatric Department, University of Pavia, Research Laboratory, Pediatric Oncohematology, IRCCS San Matteo Foundation, Pavia, Italy
Pediatr Int 52:626-30. 2010..To better characterize infants presenting with diminished immunoglobulin levels, we studied IgG subclasses, in vitro Ig production and B cell subpopulation... - Growth hormone deficiency and coeliac disease: an unusual association?Mauro Bozzola
Pediatric Department, University of Pavia, Pavia, Italy
Clin Endocrinol (Oxf) 62:372-5. 2005..To assess the occurrence of growth hormone deficiency (GHD) in patients with coeliac disease (CD)... - Secular trends in growth of African Pygmies and BantuPaola Travaglino
Paediatrics Department, University of Pavia, Foundation IRCCS Policlinico San Matteo, Pavia, Italy
Hormones (Athens) 10:144-8. 2011..The aim of this study was to investigate whether a secular trend in growth occurred during the last century in Pygmies from Cameroon (West Pygmies) and in Bantu rural farmers, the latter being studied to serve as controls... - Long-term growth hormone therapy in mitochondrial cytopathySalvatore Barberi
Department of Pediatrics, University of Pavia, IRCCS San Matteo, Pavia, Italy
Horm Res 62:103-6. 2004.... - Adult height in patients treated for isolated growth hormone deficiency: role of birth weightAlessandra Di Cesare Merlone
Department of Pediatrics, University of Pavia, Piazzale C. Golgi 2, IT-27100 Pavia, Italy
Horm Res 63:102-6. 2005..25), GH dosage (p = 0.34) and therapy duration (p = 0.52). GH treatment with a standard dose in short IGHD children leads to a normalization of AH without any significant difference between SGA and AGA patients... - Relationship between thymulin and growth hormone secretion in healthy human neonatesCristina Meazza
Pediatric Department, University of Pavia, I R C C S San Matteo, Pavia, Italy
Am J Perinatol 24:227-33. 2007..A novel interrelationship among active thymulin, zinc, and GH exists from the early up to the late phase of newborn life, in which maternal zinc, via lactation, may be involved... - Growth hormone deficiency in a patient with becker muscular dystrophy: a pediatric case reportValeria Calcaterra
Department of Internal Medicine, University of Pavia, 27100 Pavia, Italy Department of Pediatrics, IRCCS Policlinico S Matteo Foundation, 27100 Pavia, Italy
Case Report Endocrinol 2013:684249. 2013..Conclusion. The possibility of a growth hormone deficiency and treatment with GH in patients with BMD cannot be excluded, especially considering the good therapeutic response... - Mitochondrial DNA deletion in a child with mitochondrial encephalomyopathy, growth hormone deficiency, and hypoparathyroidismDenise Cassandrini
Neuromuscular Diseases Unit, Department of Pediatrics, University of Genova, Italy
J Child Neurol 21:983-5. 2006..This deletion was absent in the blood DNA of his mother and brother. This case further expands and confirms the wide clinical spectrum of mitochondrial disorders associated with single large-scale mitochondrial DNA deletions... - Influence of two different GH dosage regimens on final height, bone geometry and bone strength in GH-deficient childrenGiorgio Radetti
Department of Paediatrics, Regional Hospital of Bolzano, Italy
Eur J Endocrinol 154:479-82. 2006..The aim was to investigate the effects of two different GH dosage regimens on growth, bone geometry and bone strength...