Flavia Bortolotti

Summary

Affiliation: University of Padova
Country: Italy

Publications

  1. pmc Hepatitis C virus (HCV) genotypes in 373 Italian children with HCV infection: changing distribution and correlation with clinical features and outcome
    F Bortolotti
    Clinica Medica 5, Via Giustiniani 2, 35100 Padova, Italy
    Gut 54:852-7. 2005
  2. ncbi request reprint Epidemiological profile of 806 Italian children with hepatitis C virus infection over a 15-year period
    Flavia Bortolotti
    Clinica Medica 5, Medicina Clinica e Sperimentale University Padua, Via Giustiniani 2, 35100 Padua, Italy
    J Hepatol 46:783-90. 2007
  3. ncbi request reprint Chronic hepatitis B in children after e antigen seroclearance: final report of a 29-year longitudinal study
    Flavia Bortolotti
    Fifth Medical Clinic, University of Padova, Italy
    Hepatology 43:556-62. 2006
  4. ncbi request reprint Spontaneous regression of hepatitis B virus-associated cirrhosis developed in childhood
    F Bortolotti
    Department of Clinical and Experimental Medicine, Clinica Medica 5, University of Padua, Policlinico, Via Giustiniani 2, Italy
    Dig Liver Dis 37:964-7. 2005
  5. ncbi request reprint Interferon treatment in children with chronic hepatitis C: long-lasting remission in responders, and risk for disease progression in non-responders
    F Bortolotti
    Clinica Medica 5, University, Padua, Italy
    Dig Liver Dis 37:336-41. 2005
  6. doi request reprint Long-term course of chronic hepatitis C in children: from viral clearance to end-stage liver disease
    Flavia Bortolotti
    Clinica Medica 5, University of Padua, Padua, Italy
    Gastroenterology 134:1900-7. 2008
  7. ncbi request reprint Treatment of chronic hepatitis B in children
    Flavia Bortolotti
    Department of Clinical and Experimental Medicine, University of Padua, Clinica Medica 5, Via Giustiniani 2, 35100 Padua, Italy
    J Hepatol 39:S200-5. 2003
  8. ncbi request reprint Reversal of liver cirrhosis: a desirable clinical outcome and its pathogenic background
    Flavia Bortolotti
    Clinica Medica 5, University of Padua, Italy
    J Pediatr Gastroenterol Nutr 44:401-6. 2007
  9. doi request reprint Management of chronic hepatitis C in childhood: the impact of therapy in the clinical practice during the first 2 decades
    Flavia Bortolotti
    University of Padua, Padua, Italy
    Dig Liver Dis 43:325-9. 2011
  10. ncbi request reprint Hepatitis C virus infection associated with liver-kidney microsomal antibody type 1 (LKM1) autoantibodies in children
    Flavia Bortolotti
    Department of Pediatrics, University of Padua, Padua, Italy
    J Pediatr 142:185-90. 2003

Detail Information

Publications27

  1. pmc Hepatitis C virus (HCV) genotypes in 373 Italian children with HCV infection: changing distribution and correlation with clinical features and outcome
    F Bortolotti
    Clinica Medica 5, Via Giustiniani 2, 35100 Padova, Italy
    Gut 54:852-7. 2005
    ..This retrospective, multicentre study investigated genotype distribution and correlation with clinical features and outcome in a large series of Italian children...
  2. ncbi request reprint Epidemiological profile of 806 Italian children with hepatitis C virus infection over a 15-year period
    Flavia Bortolotti
    Clinica Medica 5, Medicina Clinica e Sperimentale University Padua, Via Giustiniani 2, 35100 Padua, Italy
    J Hepatol 46:783-90. 2007
    ..To evaluate the epidemiological profile of Italian children with hepatitis C virus (HCV) infection over a 15-year period...
  3. ncbi request reprint Chronic hepatitis B in children after e antigen seroclearance: final report of a 29-year longitudinal study
    Flavia Bortolotti
    Fifth Medical Clinic, University of Padova, Italy
    Hepatology 43:556-62. 2006
    ..Long-term monitoring is important, as is counseling on cofactors of liver damage, such as alcohol and drug abuse...
  4. ncbi request reprint Spontaneous regression of hepatitis B virus-associated cirrhosis developed in childhood
    F Bortolotti
    Department of Clinical and Experimental Medicine, Clinica Medica 5, University of Padua, Policlinico, Via Giustiniani 2, Italy
    Dig Liver Dis 37:964-7. 2005
    ..Subsidence of virus replication and of necro-inflammatory process and the efficiency of liver regeneration and repair might contribute to this favourable outcome...
  5. ncbi request reprint Interferon treatment in children with chronic hepatitis C: long-lasting remission in responders, and risk for disease progression in non-responders
    F Bortolotti
    Clinica Medica 5, University, Padua, Italy
    Dig Liver Dis 37:336-41. 2005
    ..This study describes the outcome of hepatitis C in 43 children enrolled in an open-label interferon trial, and were followed up to 66 months after stopping treatment...
  6. doi request reprint Long-term course of chronic hepatitis C in children: from viral clearance to end-stage liver disease
    Flavia Bortolotti
    Clinica Medica 5, University of Padua, Padua, Italy
    Gastroenterology 134:1900-7. 2008
    ..The natural course of chronic hepatitis C (CHC) in children is not well understood. The aim of this study was to assess the long-term course of CHC in a large sample of otherwise healthy children...
  7. ncbi request reprint Treatment of chronic hepatitis B in children
    Flavia Bortolotti
    Department of Clinical and Experimental Medicine, University of Padua, Clinica Medica 5, Via Giustiniani 2, 35100 Padua, Italy
    J Hepatol 39:S200-5. 2003
  8. ncbi request reprint Reversal of liver cirrhosis: a desirable clinical outcome and its pathogenic background
    Flavia Bortolotti
    Clinica Medica 5, University of Padua, Italy
    J Pediatr Gastroenterol Nutr 44:401-6. 2007
    ..Future prospects include the possibility of antifibrotic therapy to prevent fibrosis or favor its degradation...
  9. doi request reprint Management of chronic hepatitis C in childhood: the impact of therapy in the clinical practice during the first 2 decades
    Flavia Bortolotti
    University of Padua, Padua, Italy
    Dig Liver Dis 43:325-9. 2011
    ..We retrospectively investigated the impact of treatment in a large cohort of children with chronic hepatitis C over the past 20 years...
  10. ncbi request reprint Hepatitis C virus infection associated with liver-kidney microsomal antibody type 1 (LKM1) autoantibodies in children
    Flavia Bortolotti
    Department of Pediatrics, University of Padua, Padua, Italy
    J Pediatr 142:185-90. 2003
    ..To evaluate the clinical pattern and evolution of chronic hepatitis C in children with liver/kidney microsomal antibody type 1 autoantibodies (LKM1)...
  11. ncbi request reprint Clinical features and progression of perinatally acquired hepatitis C virus infection
    Massimo Resti
    Department of Paediatrics and Paediatric Hospital A Meyer, Florence, Italy
    J Med Virol 70:373-7. 2003
    ..The chronic progression rate of infection is high, but the associated liver disease is usually mild. High ALT levels at onset seem to offer greater opportunity of biochemical remission and loss of viremia during follow-up...
  12. ncbi request reprint Liver steatosis in children with chronic hepatitis C
    Maria Guido
    Department of Oncological and Surgical Sciences Pathology Section, University of Padova, Azienda Ospedaliera, Padova, Italy
    Am J Gastroenterol 101:2611-5. 2006
    ....
  13. doi request reprint An updated follow-up of chronic hepatitis C after three decades of observation in pediatric patients cured of malignancy
    Simone Cesaro
    Pediatric Hematology Oncology, Department of Pediatrics, University of Padova, Padova, Italy
    Pediatr Blood Cancer 55:108-12. 2010
    ..The aim of the study was to evaluate the clinical characteristics and the long-term outcome of chronic hepatitis C in a cohort of Caucasian children cured of pediatric malignancy...
  14. ncbi request reprint Chronic viral hepatitis in children: any role for the pathologist?
    Maria Guido
    Department of Diagnostic Sciences and Special Therapies, University of Padova, Padova, Italy
    Gut 57:873-7. 2008
  15. ncbi request reprint Natural history of chronic hepatitis B: special emphasis on disease progression and prognostic factors
    Giovanna Fattovich
    Department of Surgical and Gastroenterological Sciences, University of Verona, Piazzale L A Scuro, 10, Verona 37134, Italy
    J Hepatol 48:335-52. 2008
    ..There is a growing understanding of viral, host and environmental factors influencing disease progression, which ultimately could improve the management of chronic hepatitis B...
  16. ncbi request reprint Fibrosis in chronic hepatitis C acquired in infancy: is it only a matter of time?
    Maria Guido
    Dipartimento di Scienze Oncologiche and Chirurgiche, Universita degli Studi di Padova, Azienda Ospedale Padova, Padova, Italy
    Am J Gastroenterol 98:660-3. 2003
    ..The natural history of chronic hepatitis C acquired in infancy is not well understood. The progression of fibrosis was analyzed in untreated children with chronic hepatitis C virus infection and no other hepatotoxic cofactors...
  17. ncbi request reprint An epidemiological survey of hepatitis C virus infection in Italian children in the decade 1990-1999
    F Bortolotti
    Clinica Medica 5, Via Giustiniani 2, 35100 Padua, Italy
    J Pediatr Gastroenterol Nutr 32:562-6. 2001
    ..A retrospective-prospective survey of Italian children with hepatitis C virus (HCV) infection was planned in 1998 to explore the epidemiologic features of infection during the past decade...
  18. ncbi request reprint Interferon treatment of chronic hepatitis C in patients cured of pediatric malignancies
    S Cesaro
    Clinica Oncoematologica Pediatrica, Dipartimento di Pediatria, Universita di Padova, Via Giustiniani 3, 35128 Padua, Italy
    Haematologica 85:63-6. 2000
    ..Our purpose was to assess efficacy of and tolerance to interferon in a group of young patients who had acquired HCV infection during a period of chemotherapy...
  19. ncbi request reprint Treatment of chronic hepatitis C in children
    F Bortolotti
    Dipartimento di Medicina Clinica e Sperimentale, Clinica Medica 5, University of Padova, Italy
    J Hepatol 31:201-4. 1999
    ..HCV genotypes 2 and 3 and low levels of viremia could be factors in the selection of candidates with greater chances of response to interferon...
  20. ncbi request reprint Outcome of chronic hepatitis B in Caucasian children during a 20-year observation period
    F Bortolotti
    Clinica Medica 5, University of Padua, Italy
    J Hepatol 29:184-90. 1998
    ..The sequence of events from paediatric infection to severe disease in adults is only partially known. The aim of this study was to evaluate the evolution of chronic hepatitis B acquired in childhood during 20 years of follow-up...
  21. ncbi request reprint Maternal drug use is a preeminent risk factor for mother-to-child hepatitis C virus transmission: results from a multicenter study of 1372 mother-infant pairs
    Massimo Resti
    Pediatric Clinic III, University of Florence and Pediatric Hospital A Meyer, Via Luca Giordano 13, I 50132 Florence, Italy
    J Infect Dis 185:567-72. 2002
    ..51; 95% CI, 1.19-1.92; P =.0006), but no association was found with HIV-1 coinfection (AOR, 0.98; 95% CI, 0.73-1.33; P =.93). IDU, but not HIV-1 coinfection, seems to be a preeminent risk factor for vertical HCV transmission...
  22. ncbi request reprint Hepatitis B in children
    Flavia Bortolotti
    Hepatology 45:831; author reply 831. 2007
  23. ncbi request reprint Chronic hepatitis C virus infection in childhood: clinical patterns and evolution in 224 white children
    Paloma Jara
    Hospital Infantil La Paz, Madrid, Spain
    Clin Infect Dis 36:275-80. 2003
    ..Conversely, the higher rates of fibrosis observed in older patients suggest the possibility of an insidious progression of HCV-associated liver disease...
  24. ncbi request reprint Viral hepatitis: Treating hepatitis C in children: an open horizon
    Maria Guido
    Department of Medical Sciences and Special Therapies, Pathology Unit, University of Padova, Via Gabelli 61, Padua, Italy
    Nat Rev Gastroenterol Hepatol 8:247-8. 2011
    ..The results of the first controlled trial with PEG-IFN-α2a plus ribavirin are a step towards an appropriate treatment for these children...
  25. doi request reprint Monitoring SCCA-IgM complexes in serum predicts liver disease progression in patients with chronic hepatitis
    A Biasiolo
    Clinica Medica 5, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    J Viral Hepat 15:246-9. 2008
    ..8 +/- 31 U/mL/year, P < 0.0001). In conclusion, monitoring SCCA-IgM levels over time appears a useful approach to identify patients with chronic hepatitis at higher risk for cirrhosis development...
  26. ncbi request reprint Long-term outcome of hepatitis C in children
    Flavia Bortolotti
    Hepatology 39:1455; author reply 1455-6. 2004
  27. ncbi request reprint Hepatitis C virus infection in children coinfected with HIV: epidemiology and management
    Massimo Resti
    Department of Pediatrics, University of Florence, Florence, Italy
    Paediatr Drugs 4:571-80. 2002
    ..At present, treating HIV disease and monitoring HCV infection and hepatotoxicity induced by antiretroviral drugs seem to be the more reasonable approach to HCV/HIV coinfection in childhood...