Claudio Borghi

Summary

Affiliation: University of Bologna
Country: Italy

Publications

  1. ncbi request reprint [Angiotensin-converting enzyme inhibition and cardiovascular prevention: more than twenty years of clinical success]
    Claudio Borghi
    Dipartimento di Medicina Clinica e Biotecnologia, Applicata D Campanacci, Universita degli Studi, Bologna
    Ital Heart J Suppl 6:769-79. 2005
  2. pmc Fixed combination of zofenopril plus hydrochlorothiazide in the management of hypertension: a review of available data
    Claudio Borghi
    Hypertension Research Center, D Campanacci Clinical Medicine and Applied Biotechnology Department, Alma Mater Studiorum, University of Bologna, Italy
    Vasc Health Risk Manag 2:341-9. 2006
  3. doi request reprint The role of irbesartan in the treatment of patients with hypertension: a comprehensive and practical review
    Claudio Borghi
    Department of Medicine, Aging and Clinical Nephrology, University of Bologna, Bologna, Italy
    High Blood Press Cardiovasc Prev 19:19-31. 2012
  4. pmc A prospective evaluation of persistence on antihypertensive treatment with different antihypertensive drugs in clinical practice
    Maddalena Veronesi
    D Campanacci Clinical Medicine and Applied Biotechnology Department, Alma Mater Studiorum University of Bologna, Italy
    Vasc Health Risk Manag 3:999-1005. 2007
  5. ncbi request reprint VO2 kinetics in supra-anaerobic threshold constant tests allow the visualization and quantification of the O2 saving after cytochrome c oxidase inhibition by aerobic training or nitrate administration
    D Maione
    Medical and Surgical Sciences Department, S Orsola Malpighi University Hospital, Bologna, Italy
    Physiol Res 62:671-9. 2013
  6. ncbi request reprint Zofenopril and ramipril and acetylsalicylic acid in postmyocardial infarction patients with left ventricular systolic dysfunction: a retrospective analysis in hypertensive patients of the SMILE-4 study
    Claudio Borghi
    Unit of Internal Medicine, Policlinico S Orsola, University of Bologna, Bologna
    J Hypertens 31:1256-64. 2013
  7. doi request reprint Effect of zofenopril and ramipril on cardiovascular mortality in patients with chronic heart failure
    Claudio Borghi
    Heart Failure Outpatient Service, Medical and Surgical Sciences Department, University of Bologna, Bologna, Italy
    Am J Cardiol 112:90-3. 2013
  8. doi request reprint Omega-3 in antiarrhythmic therapy : cons position
    Claudio Borghi
    Division of Internal Medicine, University of Bologna, Sant Orsola Malpighi Hospital, Via Massarenti 9, 40138, Bologna, Italy
    High Blood Press Cardiovasc Prev 19:207-11. 2012
  9. ncbi request reprint Hypertension: quo vadis?
    Claudio Borghi
    Department of Internal Medicine, Aging and Kidney diseases, University of Bologna, Bologna, Italy
    Curr Vasc Pharmacol 10:739-42. 2012
  10. doi request reprint Long-term clinical experience with zofenopril
    Claudio Borghi
    Unita Operativa di Medicina Interna, Policlinico S Orsola Malpighi, University of Bologna, Via Albertoni 15 40138, Bologna, Italy
    Expert Rev Cardiovasc Ther 10:973-82. 2012

Collaborators

Detail Information

Publications95

  1. ncbi request reprint [Angiotensin-converting enzyme inhibition and cardiovascular prevention: more than twenty years of clinical success]
    Claudio Borghi
    Dipartimento di Medicina Clinica e Biotecnologia, Applicata D Campanacci, Universita degli Studi, Bologna
    Ital Heart J Suppl 6:769-79. 2005
    ..After more than 25 years from their discovery, ACE-inhibitors must be again considered among the first-line treatment in many patients with cardiovascular disease...
  2. pmc Fixed combination of zofenopril plus hydrochlorothiazide in the management of hypertension: a review of available data
    Claudio Borghi
    Hypertension Research Center, D Campanacci Clinical Medicine and Applied Biotechnology Department, Alma Mater Studiorum, University of Bologna, Italy
    Vasc Health Risk Manag 2:341-9. 2006
    ....
  3. doi request reprint The role of irbesartan in the treatment of patients with hypertension: a comprehensive and practical review
    Claudio Borghi
    Department of Medicine, Aging and Clinical Nephrology, University of Bologna, Bologna, Italy
    High Blood Press Cardiovasc Prev 19:19-31. 2012
    ....
  4. pmc A prospective evaluation of persistence on antihypertensive treatment with different antihypertensive drugs in clinical practice
    Maddalena Veronesi
    D Campanacci Clinical Medicine and Applied Biotechnology Department, Alma Mater Studiorum University of Bologna, Italy
    Vasc Health Risk Manag 3:999-1005. 2007
    ..A trend toward a better BP control was observed in response to lercanidipine vs other CCBs (p = 0.059). The present results confirm the importance of persistence on treatment for the management of hypertension in clinical practice...
  5. ncbi request reprint VO2 kinetics in supra-anaerobic threshold constant tests allow the visualization and quantification of the O2 saving after cytochrome c oxidase inhibition by aerobic training or nitrate administration
    D Maione
    Medical and Surgical Sciences Department, S Orsola Malpighi University Hospital, Bologna, Italy
    Physiol Res 62:671-9. 2013
    ..In conclusion, supra-AT VO(2) kinetics in constant load exercises permit the quantification of the inhibitory effect NO-dependent on COX after either physical training or nitrate assumption. ..
  6. ncbi request reprint Zofenopril and ramipril and acetylsalicylic acid in postmyocardial infarction patients with left ventricular systolic dysfunction: a retrospective analysis in hypertensive patients of the SMILE-4 study
    Claudio Borghi
    Unit of Internal Medicine, Policlinico S Orsola, University of Bologna, Bologna
    J Hypertens 31:1256-64. 2013
    ....
  7. doi request reprint Effect of zofenopril and ramipril on cardiovascular mortality in patients with chronic heart failure
    Claudio Borghi
    Heart Failure Outpatient Service, Medical and Surgical Sciences Department, University of Bologna, Bologna, Italy
    Am J Cardiol 112:90-3. 2013
    ..However zofenopril might be more efficacious in elderly patients, male patients, and patients with a lower ejection fraction...
  8. doi request reprint Omega-3 in antiarrhythmic therapy : cons position
    Claudio Borghi
    Division of Internal Medicine, University of Bologna, Sant Orsola Malpighi Hospital, Via Massarenti 9, 40138, Bologna, Italy
    High Blood Press Cardiovasc Prev 19:207-11. 2012
    ..In summary, the antiarrhythmic effect of omega-3 is not clearly evident and further studies are needed to investigate its beneficial effect in cardiac mortality compared with arrhythmic death...
  9. ncbi request reprint Hypertension: quo vadis?
    Claudio Borghi
    Department of Internal Medicine, Aging and Kidney diseases, University of Bologna, Bologna, Italy
    Curr Vasc Pharmacol 10:739-42. 2012
    ..This means that the future direction of the hypertension management is the simpler: the patient instead of the disease...
  10. doi request reprint Long-term clinical experience with zofenopril
    Claudio Borghi
    Unita Operativa di Medicina Interna, Policlinico S Orsola Malpighi, University of Bologna, Via Albertoni 15 40138, Bologna, Italy
    Expert Rev Cardiovasc Ther 10:973-82. 2012
    ..The effects of zofenopril on blood pressure control and cardiovascular protection clearly support its primary role for prevention and treatment of cardiovascular diseases...
  11. doi request reprint Hypertension: management perspectives
    Claudio Borghi
    University of Bologna, Internal Medicine, Aging and Kidney Diseases Department, Bologna, Italy
    Expert Opin Pharmacother 13:1999-2003. 2012
    ..So what are the possible future perspectives for high BP management?..
  12. doi request reprint Comparison between zofenopril and ramipril in combination with acetylsalicylic acid in patients with left ventricular systolic dysfunction after acute myocardial infarction: results of a randomized, double-blind, parallel-group, multicenter, European stud
    Claudio Borghi
    Unit of Internal Medicine, Policlinico S Orsola, University of Bologna, Italy
    Clin Cardiol 35:416-23. 2012
    ....
  13. pmc Excess risk attributable to traditional cardiovascular risk factors in clinical practice settings across Europe - The EURIKA Study
    Eliseo Guallar
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    BMC Public Health 11:704. 2011
    ..The objective of this study was to estimate the excess risk attributable, firstly, to the presence of CVD risk factors and, secondly, to the lack of control of these risk factors in primary prevention care across Europe...
  14. pmc Rationale and methods of the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA)
    Fernando Rodriguez-Artalejo
    Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autonoma de Madrid, CIBER of Epidemiology and Public Health, Madrid 28029, Spain
    BMC Public Health 10:382. 2010
    ..It will also assess physicians' knowledge and attitudes about CVD prevention as well as the barriers impeding effective risk factor management in clinical practice...
  15. pmc Prevalence of peripheral arterial disease in subjects with moderate cardiovascular risk: Italian results from the PANDORA study Data from PANDORA (Prevalence of peripheral Arterial disease in subjects with moderate CVD risk, with No overt vascular Disease
    Guido Sanna
    METIS Scientific Association of Italian Family Doctors, Roma, Italy
    BMC Cardiovasc Disord 11:59. 2011
    ....
  16. ncbi request reprint Effects of early angiotensin-converting enzyme inhibition in patients with non-ST-elevation acute anterior myocardial infarction
    Claudio Borghi
    Department of Clinical Medicine, University of Bologna, Bologna, Italy
    Am Heart J 152:470-7. 2006
    ..We have addressed this issue in a subgroup of NSTEMI patients enrolled in the SMILE trial...
  17. pmc Effects of early treatment with zofenopril in patients with myocardial infarction and metabolic syndrome: the SMILE Study
    Claudio Borghi
    Department of Clinical Medicine, University of Bologna Bologna, Italy
    Vasc Health Risk Manag 4:665-71. 2008
    ....
  18. ncbi request reprint Persistence of treatment and blood pressure control in elderly hypertensive patients treated with different classes of antihypertensive drugs
    Claudio Borghi
    Department of Internal Medicine and Applied Biotechnology D Campanacci, University of Bologna, Bologna, Italy
    Am J Geriatr Cardiol 16:280-6. 2007
    ..3+/-4/-2.1+/-3 mm Hg, P<.05) and beta-blockers (-4.0+/-2/-2.3+/-2 mm Hg; P<.05). The study confirms the importance of persistence with treatment for the effective management of hypertension in clinical practice...
  19. ncbi request reprint Effects of zofenopril on myocardial ischemia in post-myocardial infarction patients with preserved left ventricular function: the Survival of Myocardial Infarction Long-term Evaluation (SMILE)-ISCHEMIA study
    Claudio Borghi
    Department of Medicine, University of Bologna, Bologna, Italy
    Am Heart J 153:445.e7-14. 2007
    ..The aim of the study was to investigate the cardioprotective effects of the angiotensin-converting enzyme inhibitor zofenopril in post-myocardial infarction (MI) patients with preserved left ventricular function (LVF)...
  20. pmc Lercanidipine in hypertension
    Claudio Borghi
    Dipartimento di Medicina Clinica e Biotecnologia Applicata D Campanacci, Universita degli Studi di Bologna, Bologna, Italy
    Vasc Health Risk Manag 1:173-82. 2005
    ..The efficacy and tolerability profiles of lercanidipine make it a suitable choice for treating hypertension in a wide range of affected patients...
  21. doi request reprint Serum cholesterol levels on admission and survival in patients with acute myocardial infarction treated with zofenopril: a post hoc analysis of the Survival of Myocardial Infarction Long-term Evaluation trial
    Claudio Borghi
    Department of Internal Medicine, Aging and Kidney diseases, University Hospital of Bologna, Bologna, Italy
    Fundam Clin Pharmacol 23:641-8. 2009
    ..The presence of hypercholesterolaemia in patients with anterior myocardial infarction could be associated with more favourable effects of early ACE-inhibition...
  22. doi request reprint Rationale for the use of a fixed-dose combination in the management of hypertension: efficacy and tolerability of lercanidipine/enalapril
    Claudio Borghi
    Hypertension Research Unit, Internal Medicine, Aging and Kidney Disease Department, Sant Orsola Malpighi University Hospital, Bologna, Italy
    Clin Drug Investig 30:843-54. 2010
    ..Further studies are required to evaluate the cardiovascular protective effects of lercanidipine/enalapril...
  23. doi request reprint Hemodynamic and neurohumoral profile in patients with different types of hypertension in pregnancy
    Claudio Borghi
    Department of Internal Medicine, Aging and Kidney diseases, S Orsola Malpighi University Hospital, 40138, Bologna, Italy
    Intern Emerg Med 6:227-34. 2011
    ..On the basis of our data, we can conclude that PE is the gestation associated hypertension with the largest anatomical, functional and biohumoral involvement, and so it has to be involved in a more intensive monitoring and evaluation...
  24. pmc Tinnitus in elderly patients and prognosis of mild-to-moderate congestive heart failure: a cross-sectional study with a long-term extension of the clinical follow-up
    Claudio Borghi
    Department of Internal Medicine, Aging and Kidney diseases, Internal Medicine Unit, Bologna, Italy
    BMC Med 9:80. 2011
    ....
  25. ncbi request reprint Gender difference in hepatic steatosis index and lipid accumulation product ability to predict incident metabolic syndrome in the historical cohort of the Brisighella Heart Study
    Arrigo F G Cicero
    1 Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
    Metab Syndr Relat Disord 11:412-6. 2013
    ..17, 95% CI 1.15-1.18). Conclusion: HSI and LAP differently predict the 4-year incidence of metabolic syndrome. In women, both indexes can be considered significant predictors, whereas in men only LAP can be considered predictive. ..
  26. doi request reprint Effects of AT1 receptor and beta1 receptor blocking on blood pressure, peripheral hemodynamic and lipid profile in statin-treated hypertensive hypercholesterolemic patients
    Arrigo F G Cicero
    Hypertension Research Unit, Sant Orsola Malpighi Hospital, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy
    Fundam Clin Pharmacol 23:583-8. 2009
    ....
  27. doi request reprint Effect of a sequential training programme on inflammatory, prothrombotic and vascular remodelling biomarkers in hypertensive overweight patients with or without metabolic syndrome
    Arrigo F G Cicero
    Department of Internal Medicine, Aging and Kidney diseases, University of Bologna, Bologna, Italy
    Eur J Cardiovasc Prev Rehabil 16:698-704. 2009
    ..It is not known whether serum level of vascular remodelling parameters, such as matrix metalloproteinases could be modulated by physical activity and whether the eventual change could be influenced by metabolic syndrome (MS) diagnosis...
  28. doi request reprint Blood pressure and metabolic effect of a combination of lercanidipine with different antihypertensive drugs in clinical practice
    Arrigo F G Cicero
    Department of Internal Medicine, Aging and Kidney diseases, S Orsola Malpighi University Hospital, University of Bologna, Pad 2 Via Albertoni 15, Bologna, Italy
    Clin Exp Hypertens 34:113-7. 2012
    ..Moreover, the association of lercanidipine with renin-angiotensin system blockers is also associated with significant improvements in triglycerides and fasting plasma glucose...
  29. doi request reprint Gender-specific haemodynamic and metabolic effects of a sequential training programme on overweight-obese hypertensives
    Arrigo Francesco Giuseppe Cicero
    Internal Medicine, Aging and Kidney Diseases Department, University of Bologna, Bologna, Italy
    Blood Press 18:111-6. 2009
    ..To evaluate the short-term cardiometabolic effect of a sequential physical activity programme on pharmacologically untreated hypertensive overweight women and on age-matched men...
  30. doi request reprint Long-term effect of a dietary education program on postmenopausal cardiovascular risk and metabolic syndrome: the Brisighella Heart Study
    Arrigo F G Cicero
    Internal Medicine, Aging and Kidney Diseases Department, Alma Mater Studiorum University of Bologna, Italy
    J Womens Health (Larchmt) 19:133-7. 2010
    ..To evaluate whether a nutritional education intervention on a general population cohort is able to balance the metabolic effects of incident menopause in a large sample of perimenopausal women...
  31. ncbi request reprint The relationship between systolic blood pressure and cardiovascular risk--results of the Brisighella Heart Study
    Claudio Borghi
    Department of Internal Medicine, University of Bologna, Bologna, Italy
    J Clin Hypertens (Greenwich) 5:47-52. 2003
    ..The prognostic significance of pulse pressure was also demonstrated. The importance of SBP as seen in the Framingham Heart Study may be generalized to a European population with differences in diet and other risk factors...
  32. doi request reprint Omega 3 polyunsaturated fatty acids supplementation and blood pressure levels in hypertriglyceridemic patients with untreated normal-high blood pressure and with or without metabolic syndrome: a retrospective study
    Arrigo F G Cicero
    Lipid Research Unit, Department of Internal Medicine, Aging and Kidney diseases, Alma Mater Studiorum University of Bologna, Bologna, Italy
    Clin Exp Hypertens 32:137-44. 2010
    ..No significant difference was perceived in the metabolic syndrome subgroup. The main determinants of the PUFA anti-hypertensive effect appear to be the basal blood pressure level and age...
  33. doi request reprint Red yeast rice improves lipid pattern, high-sensitivity C-reactive protein, and vascular remodeling parameters in moderately hypercholesterolemic Italian subjects
    Arrigo F G Cicero
    Medical and Surgical Sciences Department, University of Bologna, Bologna, Italy
    Nutr Res 33:622-8. 2013
    ..These results have to be confirmed in larger patient samples and longer studies. ..
  34. ncbi request reprint Improved tolerability of the dihydropyridine calcium-channel antagonist lercanidipine: the lercanidipine challenge trial
    Claudio Borghi
    Department of Internal Medicine, University of Bologna, Bologna, Italy
    Blood Press Suppl 1:14-21. 2003
    ..1/86.7 mmHg. In this open-label study, lercanidipine compared with other CA seems to provide a significant improvement in tolerability with comparable antihypertensive effect...
  35. ncbi request reprint Improved tolerability of the dihydropyridine calcium-channel antagonist lercanidipine: the lercanidipine challenge trial
    Claudio Borghi
    Department of Internal Medicine, University of Bologna, Bologna, Italy
    Blood Press 12:14-21. 2003
    ..1/86.7 mmHg. In this open-label study, lercanidipine compared with other CA seems to provide a significant improvement in tolerability with comparable antihypertensive effect...
  36. doi request reprint Lactotripeptides effect on office and 24-h ambulatory blood pressure, blood pressure stress response, pulse wave velocity and cardiac output in patients with high-normal blood pressure or first-degree hypertension: a randomized double-blind clinical trial
    Arrigo F G Cicero
    Hypertension Research Center, Department of Internal Medicine, Aging and Kidney Disease, University of Bologna, Bologna, Italy
    Hypertens Res 34:1035-40. 2011
    ..No effect was observed on parameters related to fluid dynamics or vascular resistance. LTPs positively influenced the office SBP, PWV, SV, SV index, ACI and VI in patients with high-normal BP or first-degree hypertension...
  37. ncbi request reprint Persistence on treatment and blood pressure control with different first-line antihypertensive treatments: a prospective evaluation
    Maria Grazia Prandin
    D Campanacci Clinical Medicine and Applied Biotechnology Department, Alma Mater Studiorum, University of Bologna, Italy
    Clin Exp Hypertens 29:553-62. 2007
    ..46.6%). Systolic and diastolic BP decreased more in patients treated with ARBs (-11.2/-5.8 mmHg), ACE inhibitors (-10.5/-5.1 mmHg), and CCBs (-8.5/-4.6 mmHg) when compared to beta-blockers (-4.0/-2.3 mmHg) and diuretics (-2.3/-2.1 mmHg)...
  38. ncbi request reprint A review of the angiotensin-converting enzyme inhibitor, zofenopril, in the treatment of cardiovascular diseases
    Claudio Borghi
    University of Bologna, Department of Internal Medicine, S Orsola Hospital, 40138 Bologna, Italy
    Expert Opin Pharmacother 5:1965-77. 2004
    ....
  39. ncbi request reprint Interaction between serum cholesterol levels and the renin-angiotensin system on the new onset of arterial hypertension in subjects with high-normal blood pressure
    Claudio Borghi
    Department of Internal Medicine, University of Bologna, Bologna, Italy
    J Hypertens 25:2051-7. 2007
    ..To investigate the possible interactions between serum cholesterol levels and the renin-angiotensin system on the development of stable hypertension in subjects with high-normal blood pressure (BP)...
  40. ncbi request reprint Trends in blood pressure control and antihypertensive treatment in clinical practice: the Brisighella Heart Study
    Claudio Borghi
    Department of Medicine, University of Bologna, Bologna, Italy
    J Hypertens 22:1707-16. 2004
    ..To assess trends in blood pressure (BP) awareness, control, treatment and use of different antihypertensive medications in a cohort of hypertensive patients...
  41. doi request reprint Combined nutraceutical approach to postmenopausal syndrome and vascular remodeling biomarkers
    Arrigo F G Cicero
    Internal Medicine, Aging and Kidney Disease Department, University of Bologna, Bologna, Italy
    J Altern Complement Med 19:582-7. 2013
    ....
  42. doi request reprint Metabolic syndrome, adipokines and hormonal factors in pharmacologically untreated adult elderly subjects from the Brisighella Heart Study historical cohort
    Arrigo F G Cicero
    Internal Medicine, Aging and Kidney Disease Department, University of Bologna, Bologna, Italy
    Obes Facts 5:319-26. 2012
    ..Our aim was to evaluate the relation of the sex hormone pattern and the serum level of the main adipokines with metabolic syndrome (MS) and its components in a cohort of pharmacologically untreated adult elderly subjects...
  43. doi request reprint The PANDORA study: peripheral arterial disease in patients with non-high cardiovascular risk
    Claudio Cimminiello
    Department of Medicine, Vimercate Hospital, Via Cesare Battisti 23, Vimercate MI 20059, Italy
    Intern Emerg Med 6:509-19. 2011
    ..These patients should be carefully screened, and ABI measured, so that therapeutic interventions known to diminish their increased CV risk may be offered...
  44. doi request reprint Relationship between blood pressure, cholesterolemia and serum apolipoprotein B in a large population sample: the Brisighella Heart Study
    Arrigo F G Cicero
    Internal Medicine, Aging and Kidney Disease Department, University of Bologna, Bologna, Italy
    J Hypertens 30:492-6. 2012
    ..The objective is to evaluate the relationship between cholesterolemia, serum apolipoprotein B (apoB) level and blood pressure in a large sample of general population...
  45. ncbi request reprint Could echocardiography yield a cardiovascular profile of the tinnitus prone subject?
    Antonio Pirodda
    Department of Surgical and Anaesthesiological Sciences, University of Bologna, Italy
    Med Hypotheses 70:252-4. 2008
    ....
  46. doi request reprint Hemodynamic effects of lactotripeptides from casein hydrolysate in Mediterranean normotensive subjects and patients with high-normal blood pressure: a randomized, double-blind, crossover clinical trial
    Arrigo F G Cicero
    Hypertension Research Unit, Sant Orsola Malpighi University Hospital, Bologna, Italy
    J Med Food 13:1363-8. 2010
    ..In conclusion, diurnal diastolic BP is significantly reduced by lactrotripeptide supplementation in untreated Mediterranean subjects with normal or high-normal BP. Office systolic BP is reduced only in subjects with high-normal BP...
  47. ncbi request reprint Effects of the early ACE inhibition in diabetic nonthrombolyzed patients with anterior acute myocardial infarction
    Claudio Borghi
    Department of Internal Medicine, University of Bologna, Bologna, Italy
    Diabetes Care 26:1862-8. 2003
    ....
  48. ncbi request reprint Serum cholesterol levels, blood pressure response to stress and incidence of stable hypertension in young subjects with high normal blood pressure
    Claudio Borghi
    Department of Internal Medicine, University of Bologna, Bologna, Italy
    J Hypertens 22:265-72. 2004
    ..Elevated serum cholesterol levels are common in patients with high blood pressure (BP) and could contribute to the progression of the hypertensive disease...
  49. ncbi request reprint Association between different lipid-lowering treatment strategies and blood pressure control in the Brisighella Heart Study
    Claudio Borghi
    Department of Internal Medicine, University of Bologna, Bologna, Italy
    Am Heart J 148:285-92. 2004
    ....
  50. ncbi request reprint Use of lipid-lowering drugs and blood pressure control in patients with arterial hypertension
    Claudio Borghi
    Department of Internal Medicine, University of Bologna, Italy
    J Clin Hypertens (Greenwich) 4:277-85. 2002
    ..The capacity of statins to improve blood pressure control may represent a useful tool for improvement in the prevention of cardiovascular diseases...
  51. doi request reprint Inner ear dysfunction of uncertain origin: a multidisciplinary approach could give something more
    Antonio Pirodda
    Department of Specialistic Surgical and Anaesthesiological Sciences, University of Bologna, Via Massarenti n 9, 40138 Bologna, Italy
    Med Hypotheses 72:188-9. 2009
    ....
  52. ncbi request reprint Vascular remodeling and prothrombotic markers in subjects affected by familial combined hyperlipidemia and/or metabolic syndrome in primary prevention for cardiovascular disease
    Arrigo F G Cicero
    GC Descovich Atherosclerosis and Metabolic Disease Research Unit, D Campanacci Clinical Medicine and Applied Biotechnology Department, Alma Mater Studiorum University of Bologna, Bologna, Italy
    Endothelium 14:193-8. 2007
    ..However, the superposition of MS on FCH further increases the plasma level of these parameters. The prognostic value of this observation has to be evaluated...
  53. ncbi request reprint Double-blind comparison between zofenopril and lisinopril in patients with acute myocardial infarction: results of the Survival of Myocardial Infarction Long-term Evaluation-2 (SMILE-2) study
    Claudio Borghi
    Department of Medicine, University of Bologna, Bologna, Italy
    Am Heart J 145:80-7. 2003
    ..However, no direct comparisons have been performed between different ACE inhibitors in the same patient population...
  54. ncbi request reprint Relative role of systolic, diastolic and pulse pressure as risk factors for cardiovascular events in the Brisighella Heart Study
    Claudio Borghi
    Department of Internal Medicine, University of Bologna, Bologna, Italy
    J Hypertens 20:1737-42. 2002
    ..The objective of this study was to determine the contribution of elevated blood pressure parameters to the long-term incidence of cardiovascular events...
  55. ncbi request reprint The treatment of hypertension in pregnancy
    Claudio Borghi
    Department of Internal Medicine, University of Bologna, Bologna, Italy
    J Hypertens Suppl 20:S52-6. 2002
    ....
  56. ncbi request reprint Is tinnitus useful in early detection of incoming heart decompensation?
    Claudio Borghi
    Department of Internal Medicine, University of Bologna, Policlinico S Orsola Malpighi, Via Massarenti n 9, 40138 Bologna, Italy
    Med Hypotheses 67:437-9. 2006
    ..In this paper, the hypothesis of resorting to tinnitus as a simple warning method for self detecting a possibly incoming cardiovascular imbalance in patients with heart failure (HF) is advanced...
  57. doi request reprint Lipid-lowering treatment in patients at high cardiovascular risk discharged from an Italian hospital
    Alessandro Spighi
    Internal Medicine, Aging and Kidney Disease Department, University of Bologna, Bologna, Italy
    J Cardiovasc Med (Hagerstown) 14:270-5. 2013
    ..The aim of our study was to determine the accuracy of antihypercholesterolemic treatment in high-risk patients [low-density lipoprotein (LDL) > 100 mg/dl] discharged from hospital...
  58. pmc Do the lactotripeptides isoleucine-proline-proline and valine-proline-proline reduce systolic blood pressure in European subjects? A meta-analysis of randomized controlled trials
    Arrigo F G Cicero
    Internal Medicine, Aging and Kidney Disease Department, University of Bologna, Bologna, Italy
    Am J Hypertens 26:442-9. 2013
    ..This decrease is convincingly shown in subjects of Asian origin, but less consistent results have been obtained in European populations...
  59. ncbi request reprint Leisure-time physical activity and cardiovascular disease mortality: the Brisighella Heart Study
    Arrigo F G Cicero
    Department of Internal Medicine, Aging and Kidney diseases, University of Bologna, Bologna, Italy
    J Cardiovasc Med (Hagerstown) 13:559-64. 2012
    ....
  60. doi request reprint Diuretics in Meniere disease: a therapy or a potential cause of harm?
    Antonio Pirodda
    Department of Specialist Surgical and Anaesthesiological Sciences, S Orsola Malpighi University Hospital, Via Massarenti 9, 40138 Bologna, Italy
    Med Hypotheses 77:869-71. 2011
    ....
  61. doi request reprint Meniere's disease and the use of proton pump inhibitors
    Antonio Pirodda
    Department of Specialist Surgical and Anesthesiological Sciences, University of Bologna, Italy
    Swiss Med Wkly 140:w13104. 2010
    ..A preliminary step was made by retrospectively analysing the number of menieric crisis in group of patients suffering from MD and using PPI for other reasons as compared to a group of menieric subjects who had never used PPI...
  62. doi request reprint Could statins exert a protective effect on epistaxis of systemic origin?
    Antonio Pirodda
    Department of Specialist Surgical and Anaesthesiological Sciences, S Orsola Malpighi University Hospital, Via Massarenti 9, 40138 Bologna, Italy
    Med Hypotheses 76:445-6. 2011
    ....
  63. ncbi request reprint Central hemodynamic modifications in diabetes mellitus
    Davide Agnoletti
    Paris Descartes University, AP HP, Diagnosis and Therapeutic Center, Hotel Dieu, 1 Place du Parvis Notre Dame, 75004 Paris, France Department of Internal Medicine, University of Bologna, Via Albertoni 15, 40138 Bologna, Italy
    Atherosclerosis 230:315-21. 2013
    ..It remains to be determined whether IT should be considered as a marker of diabetes severity that leads to increased arterial stiffness, or whether it has a direct/indirect effect on arterial wall modifications. ..
  64. doi request reprint Population health needs assessment and healthcare services use in a 3 years follow-up on administrative and clinical data: results from the Brisighella Heart Study
    Arrigo F G Cicero
    Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
    High Blood Press Cardiovasc Prev 21:45-51. 2014
    ....
  65. ncbi request reprint Factors associated with 2-year persistence in fully non reimbursed lipid-lowering treatments
    Arrigo F G Cicero
    Medicine and Surgery Sciences Department, University of Bologna, S Orsola Malpighi University Hospital, Via Albertoni, 15, 40138 Bologna, Italy Electronic address
    Atherosclerosis 235:81-3. 2014
    ..to evaluate the main factors associated with long-term persistence in fully paid lipid-lowering treatment...
  66. doi request reprint Evidence of clinically relevant efficacy for dietary supplements and nutraceuticals
    Arrigo F G Cicero
    Medical and Surgical Science Department, University of Bologna, Via Albertoni 15 Pad 2, 40138, Bologna, Italy
    Curr Hypertens Rep 15:260-7. 2013
    ....
  67. pmc Influence of metabolic syndrome superposition on familial combined hyperlipoproteinemia cardiovascular complication rate
    Arrigo F G Cicero
    Atherosclerosis and Metabolic disease Research Unit, Internal Medicine, Aging and Kidney Diseases Department, Alma Mater Studiorum University of Bologna, Italy
    Arch Med Sci 9:238-42. 2013
    ..We aimed to evaluate whether the presence of the MS per se could account for a significant part of the elevated cardiovascular disease (CVD) risk associated with FCHL...
  68. ncbi request reprint Interactions between hypercholesterolemia and hypertension: implications for therapy
    Claudio Borghi
    Department of Medicine, University of Bologna, Italy
    Curr Opin Nephrol Hypertens 11:489-96. 2002
    ..The purpose of the present review is to summarize the available information that supports the therapeutic role for the concomitant and aggressive management of hypercholesterolemia and hypertension...
  69. ncbi request reprint Greater pressor reactivity in women with pre-eclampsia is not related to specific psychological or emotional stressors
    Nicolino C F Rossi
    Department of Psychology, University of Bologna, v le Berti Pichat 5, 40127 Bologna, Italy
    Psychol Rep 107:415-23. 2010
    ..Present results confirm a greater pressor reactivity in these women with pre-eclampsia but does not specifically support that this was related to psychological or emotional stress...
  70. ncbi request reprint [Hypercholesterolemia as cardiovascular risk in hypertensive patients. Therapeutic implications: efficiency of statins]
    Claudio Borghi
    Divisione di Medicina Interna, Dipartimento di Medicina Clinica e Biotecnologia Applicata, Università Alma Mater Studiorum, Bologna
    Recenti Prog Med 94:421-6. 2003
    ....
  71. ncbi request reprint Omega-3 fatty acids: a promising possible treatment for Meniere's disease and other inner ear disorders of unknown origin?
    Claudio Borghi
    Department of Internal Medicine and Ageing, University of Bologna, Italy
    Med Hypotheses 79:468-70. 2012
    ....
  72. ncbi request reprint Omega-3 polyunsaturated fatty acids: their potential role in blood pressure prevention and management
    Arrigo F G Cicero
    Hypertension Research Unit, Internal Medicine, Aging and Kidney Diseases Department, Alma Mater Studiorum University of Bologna, Bologna, Italy
    Curr Vasc Pharmacol 7:330-7. 2009
    ..Future research will clarify if PUFA supplementation could improve the antihypertensive action of specific BP lowering drug classes and of statins...
  73. doi request reprint Tinnitus as a warning for preventing vasovagal syncope
    Antonio Pirodda
    Department of Specialistic Surgical and Anaesthesiological Sciences, University of Bologna, Policlinico S Orsola Malpighi, Via Massarenti n 9, 40138 Bologna, Italy
    Med Hypotheses 73:370-1. 2009
    ....
  74. ncbi request reprint Is there a role for atrial peptides in the labyrinthine "disease"?
    Claudio Borghi
    Department of Internal Medicine, University of Bologna, Italy
    Med Hypotheses 66:1188-90. 2006
    ....
  75. ncbi request reprint Compliance with therapy in hypertensive patients
    Claudio Borghi
    Department of Internal Medicine, University of Bologna, Bologna, Italy
    Intern Emerg Med 1:175-6. 2006
  76. doi request reprint Global cardiovascular disease risk management in italian patients with metabolic syndrome in the clinical practice setting
    Ettore Ambrosioni
    Internal Medicine, Aging and Kidney Diseases Department, Sant Orsola Malpighi Hospital University of Bologna, Via Massarenti 9, 40138, Bologna, Italy
    High Blood Press Cardiovasc Prev 15:37-45. 2008
    ....
  77. ncbi request reprint Different effect of psyllium and guar dietary supplementation on blood pressure control in hypertensive overweight patients: a six-month, randomized clinical trial
    Arrigo F G Cicero
    GC Descovich Atherosclerosis Research Centre, D Campanacci Clinical Medicine and Applied Biotechnology Dept, University of Bologna, Italy
    Clin Exp Hypertens 29:383-94. 2007
    ..In our study, six-month supplementation with psyllium fiber, but not with guar fiber nor standard diet, appears to significantly reduce both SBP and DBP in hypertensive overweight subjects...
  78. pmc Application of polyunsaturated fatty acids in internal medicine: beyond the established cardiovascular effects
    Arrigo F G Cicero
    Medical and Surgical Sciences Department, University of Bologna, Italy
    Arch Med Sci 8:784-93. 2012
    ....
  79. pmc Fixed combination of lercanidipine and enalapril in the management of hypertension: focus on patient preference and adherence
    Claudio Borghi
    Internal Medicine, Aging and Kidney Disease Department, University of Bologna, Italy
    Patient Prefer Adherence 6:449-55. 2012
    ..In addition, combining two antihypertensive agents with different mechanisms of action may provide greater protection against major cardiovascular events and the development of end-organ damage...
  80. pmc Prevalence of peripheral arterial disease in patients at non-high cardiovascular risk. Rationale and design of the PANDORA study
    Claudio Cimminiello
    Department of Medicine, Via Cesare Battisti 23, Vimercate Hospital, Vimercate MI, 20059, Italy
    BMC Cardiovasc Disord 10:35. 2010
    ..Secondary objectives include documenting the prevalence and treatment of cardiovascular risk factors and the characteristics of both patients and physicians as possible determinants for PAD under-diagnosis...
  81. ncbi request reprint [Atherosclerosis regression and plaque stabilization: comparison of therapeutic targets]
    Sergio D'Addato
    Dipartimento di Medicina Interna, dell lnvecchiamento e Scienze Nefrologiche, Azienda Ospedaliera Universitaria S Orsola Malpighi, Universita degli Studi, Bologna
    G Ital Cardiol (Rome) 10:13S-17S. 2009
    ..The best approach seems to be achieved with the combination of a specific intervention on lipid profile together with a targeted control of blood pressure...
  82. pmc Adipokines and sexual hormones associated with the components of the metabolic syndrome in pharmacologically untreated subjects: data from the brisighella heart study
    Arrigo F G Cicero
    Department of Internal Medicine, Aging and Kidney Disease Department, University of Bologna, 40138 Bologna, Italy
    Int J Endocrinol 2011:724816. 2011
    ..87, 95% CI 0.79-0.95). In conclusion, in a sample of pharmacologically untreated subjects, leptin/adiponectin ratio seems to be the factor more strongly associated to MS and its components...
  83. ncbi request reprint Lipoprotein(a) and other serum lipid subfractions influencing primary patency after infrainguinal percutaneous transluminal angioplasty
    Federica Giovanetti
    Department of Specialized Vascular Surgery and Anesthesiology, Alma Mater Studiorum, University of Bologna, Policlinico S Orsola Malpighi, Bologna, Italy
    J Endovasc Ther 16:389-96. 2009
    ..To evaluate the influence of serum lipid subfraction concentrations on arterial patency after percutaneous transluminal angioplasty (PTA) in patients with infrainguinal peripheral artery occlusive disease (PAOD)...
  84. ncbi request reprint Is it the the renin-angiotensin-aldosterone blockade a comprehensive tool for the management of cardiovascular risk?
    Claudio Borghi
    J Hypertens 22:463-5. 2004
  85. ncbi request reprint Acute administration of angiotensin converting enzyme inhibitors in thrombolysed myocardial infarction patients is associated with a decreased incidence of heart failure, but an increased re-infarction risk
    Adriaan A Voors
    Department of Cardiology, University Hospital Groningen, The Netherlands
    Cardiovasc Drugs Ther 19:119-24. 2005
    ..The aim of the present study was to evaluate the effects of acute ACE-inhibitor treatment...
  86. ncbi request reprint Blood pressure control in Italy: results of recent surveys on hypertension
    Massimo Volpe
    Division of Cardiology, II Faculty of Medicine, University of Rome La Sapienza, Sant Andrea Hospital, Rome, Italy
    J Hypertens 25:1491-8. 2007
    ..Blood pressure (BP) control is reported to be poor in hypertensive patients worldwide...
  87. ncbi request reprint Hypertension prevalence, awareness, control and association with metabolic abnormalities in the San Marino population: the SMOOTH study
    Giuseppe Mancia
    Clinica Medica and Department Medicina Clinica, Prevenzione e Biotecnologie Sanitarie, Universita di Milano Bicocca, Italy
    J Hypertens 24:837-43. 2006
    ....
  88. ncbi request reprint [Hypertensive patients can benefit from a new generation of calcium channel blockers. Lercanidipine: effective with few side effects]
    Claudio Borghi
    Rev Med Suisse 2:1266-7. 2006
  89. ncbi request reprint Do ACE inhibitors or angiotensin II antagonists reduce total mortality and arrhythmic mortality? A critical review of controlled clinical trials
    Franco Naccarella
    Cardiology Department, Day Hospital Tiarini Corticella, Azienda USL, Citta di Bologna, Cardiology University of Parma, Italy
    Curr Opin Cardiol 17:6-18. 2002
    ..Finally, according to these clinical evidences, in the last part of the review, we stress the need for a more widespread implementation of ACE-I and AII-a in treating CHF patients...
  90. ncbi request reprint [Disease management for heart failure patients: role of wireless technologies for telemedicine. The ICAROS project]
    Alessandra Villani
    Cardiologia, Ospedale San Luca, Istituto Auxologico Italiano IRCCS, Milano
    G Ital Cardiol (Rome) 8:107-14. 2007
    ....
  91. ncbi request reprint Early and late angiotensin-converting enzyme inhibition after myocardial infarction: an overview of randomized clinical trials
    Ettore Ambrosioni
    Am J Med 115:503-4. 2003
  92. ncbi request reprint Pharmacotherapeutic approaches for decompensated heart failure: a role for the calcium sensitiser, levosimendan?
    Barry Greenberg
    Department of Medicine, University of California School of Medicine, San Diego, CA 92103, USA
    Eur J Heart Fail 5:13-21. 2003
    ..Calcium sensitisation is therefore emerging as a promising treatment approach in this challenging therapeutic area...
  93. ncbi request reprint Central blood pressure as estimate of cardiovascular risk: potentials and limitations
    Guido Grassi
    J Hypertens 26:16-7. 2008