Stefano Bonini

Summary

Affiliation: University Campus Bio-Medico
Country: Italy

Publications

  1. ncbi request reprint Allergic eye disorders
    Leonard Bielory
    UMDNJ New Jersey Medical School, Newark, New Jersey, USA
    Clin Allergy Immunol 16:311-23. 2002
  2. ncbi request reprint Nerve growth factor (NGF) and lenses: effects of NGF in an in vitro rat model of cataract
    Emiliano Ghinelli
    Department of Ophthalmology, University of Rome, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 241:845-51. 2003
  3. ncbi request reprint Pharmacokinetics of conjunctivally applied nerve growth factor in the retina and optic nerve of adult rats
    Alessandro Lambiase
    Interdisciplinary Research Center, Laboratory of Ophthalmology, University of Rome Campus Bio Medico, Italy
    Invest Ophthalmol Vis Sci 46:3800-6. 2005
  4. pmc Molecular basis for keratoconus: lack of TrkA expression and its transcriptional repression by Sp3
    Alessandro Lambiase
    Department of Ophthalmology, University Campus Bio Medico, G B Bietti Eye Foundation, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy
    Proc Natl Acad Sci U S A 102:16795-800. 2005
  5. ncbi request reprint Conjunctival mucin deficiency in complete androgen insensitivity syndrome (CAIS)
    Flavio Mantelli
    Interdisciplinary Center for Biomedical Research CIR Laboratory of Ophthalmology, Campus Bio Medico University of Rome, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 245:899-902. 2007
  6. pmc Sands of sahara after LASIK in avellino corneal dystrophy
    Flavio Mantelli
    Department of Ophthalmology, Campus Bio Medico University of Rome, Via Alvaro del Portillo 21, 00128 Rome, Italy
    Case Rep Ophthalmol Med 2012:413010. 2012
  7. pmc Nerve growth factor has a modulatory role on human primary fibroblast cultures derived from vernal keratoconjunctivitis-affected conjunctiva
    Alessandra Micera
    CIR Laboratory of Ophthalmology, University Campus Bio Medico, Rome, Italy
    Mol Vis 13:981-7. 2007
  8. pmc Tear levels of neuropeptides increase after specific allergen challenge in allergic conjunctivitis
    Marta Sacchetti
    Department of Ophthalmology, University of Rome Campus Bio Medico, Rome, Italy
    Mol Vis 17:47-52. 2011
  9. ncbi request reprint Itchy-dry eye associated with polycystic ovary syndrome
    Stefano Bonini
    Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University Campus Bio Medico of Rome, Rome, Italy
    Am J Ophthalmol 143:763-771. 2007
  10. ncbi request reprint Expression of Toll-like receptors in healthy and allergic conjunctiva
    Stefano Bonini
    CIR Laboratory of Ophthalmology, Campus Bio Medico and G B Bietti Eye Foundation, Rome, Italy
    Ophthalmology 112:1528; discussion 1548-9. 2005

Collaborators

Detail Information

Publications70

  1. ncbi request reprint Allergic eye disorders
    Leonard Bielory
    UMDNJ New Jersey Medical School, Newark, New Jersey, USA
    Clin Allergy Immunol 16:311-23. 2002
  2. ncbi request reprint Nerve growth factor (NGF) and lenses: effects of NGF in an in vitro rat model of cataract
    Emiliano Ghinelli
    Department of Ophthalmology, University of Rome, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 241:845-51. 2003
    ..The aims of this study are to investigate the presence and production of nerve growth factor (NGF) in the rat lens in basal conditions and to evaluate, in vitro, the role of NGF in a model of xylose-induced cataract...
  3. ncbi request reprint Pharmacokinetics of conjunctivally applied nerve growth factor in the retina and optic nerve of adult rats
    Alessandro Lambiase
    Interdisciplinary Research Center, Laboratory of Ophthalmology, University of Rome Campus Bio Medico, Italy
    Invest Ophthalmol Vis Sci 46:3800-6. 2005
    ..The present study sought to establish the bioavailability of topical NGF to the retina and optic nerve in rats...
  4. pmc Molecular basis for keratoconus: lack of TrkA expression and its transcriptional repression by Sp3
    Alessandro Lambiase
    Department of Ophthalmology, University Campus Bio Medico, G B Bietti Eye Foundation, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy
    Proc Natl Acad Sci U S A 102:16795-800. 2005
    ..This mechanism for the transcriptional repression of the TrkA(NGFR) gene can provide the platform for the development of a therapeutic strategy...
  5. ncbi request reprint Conjunctival mucin deficiency in complete androgen insensitivity syndrome (CAIS)
    Flavio Mantelli
    Interdisciplinary Center for Biomedical Research CIR Laboratory of Ophthalmology, Campus Bio Medico University of Rome, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 245:899-902. 2007
    ..Decreased mucin levels contribute in explaining the tear film instability in CAIS and should be considered an additional cause of dry eye in sex steroid hormone pathology...
  6. pmc Sands of sahara after LASIK in avellino corneal dystrophy
    Flavio Mantelli
    Department of Ophthalmology, Campus Bio Medico University of Rome, Via Alvaro del Portillo 21, 00128 Rome, Italy
    Case Rep Ophthalmol Med 2012:413010. 2012
    ..The risk of developing interstitial keratitis, as in the case presented here, represents another valid reason for avoiding LASIK in patients with ACD...
  7. pmc Nerve growth factor has a modulatory role on human primary fibroblast cultures derived from vernal keratoconjunctivitis-affected conjunctiva
    Alessandra Micera
    CIR Laboratory of Ophthalmology, University Campus Bio Medico, Rome, Italy
    Mol Vis 13:981-7. 2007
    ..NGF, a pleiotrophic factor with documented profibrogenic activities, is produced by inflammatory and structural cells populating the VKC conjunctiva and is increased in the serum and tears of VKC patients...
  8. pmc Tear levels of neuropeptides increase after specific allergen challenge in allergic conjunctivitis
    Marta Sacchetti
    Department of Ophthalmology, University of Rome Campus Bio Medico, Rome, Italy
    Mol Vis 17:47-52. 2011
    ..In this study, we aimed at evaluating the role of substance P (SP), calcitonine gene related peptide (CGRP), neuropeptide Y (NPY) and vasoactive intestinal peptide (VIP) in allergic reactions of the ocular surface...
  9. ncbi request reprint Itchy-dry eye associated with polycystic ovary syndrome
    Stefano Bonini
    Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University Campus Bio Medico of Rome, Rome, Italy
    Am J Ophthalmol 143:763-771. 2007
    ..The authors aimed to define the ocular symptomatology of women with polycystic ovaries and hyperandrogenism...
  10. ncbi request reprint Expression of Toll-like receptors in healthy and allergic conjunctiva
    Stefano Bonini
    CIR Laboratory of Ophthalmology, Campus Bio Medico and G B Bietti Eye Foundation, Rome, Italy
    Ophthalmology 112:1528; discussion 1548-9. 2005
    ..To investigate the expression of toll-like receptors (TLRs) in healthy and active vernal keratoconjunctivitis (VKC) conjunctiva...
  11. ncbi request reprint Clinical grading of vernal keratoconjunctivitis
    Stefano Bonini
    Department of Ophthalmology, University of Rome Campus Bio Medico, Rome, Italy
    Curr Opin Allergy Clin Immunol 7:436-41. 2007
    ..Furthermore, a new grading system of vernal keratoconjunctivitis based on the severity of the disease is proposed. Different treatment options are discussed based on the clinical grade of vernal keratoconjunctivitis...
  12. ncbi request reprint Corneal ulcer as an atypical presentation of ocular cicatricial pemphigoid
    R Sgrulletta
    Department of Ophthalmology, University of Roma, Campus Bio Medico G B Bietti Eye Foundation, IRCCS, Roma, Italy
    Eur J Ophthalmol 17:121-3. 2007
    ..To describe three patients, each presenting noninfective corneal epithelial damage as first manifestation of ocular cicatricial pemphigoid (OCP)...
  13. doi request reprint In vitro evidence of nerve growth factor effects on human conjunctival epithelial cell differentiation and mucin gene expression
    Alessandro Lambiase
    CIR Laboratory of Ophthalmology, University Campus Bio Medico, Rome, Italy
    Invest Ophthalmol Vis Sci 50:4622-30. 2009
    ..The aim of this study was to evaluate in vitro the effect of NGF on conjunctival goblet cell differentiation and mucin production and secretion...
  14. doi request reprint Retinal p75 and bax overexpression is associated with retinal ganglion cells apoptosis in a rat model of glaucoma
    Marco Coassin
    CIR, Laboratory of Ophthalmology, University Campus Bio Medico, Via Alvaro del Portillo, 21, 00128, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 246:1743-9. 2008
    ..Therefore, this study sought to address whether timely changes in NGF and its receptors, trkA(NGFR) and p75(NTR), might explain the progression of retinal damage during experimental glaucoma...
  15. pmc Nerve growth factor modulates toll-like receptor (TLR) 4 and 9 expression in cultured primary VKC conjunctival epithelial cells
    Alessandra Micera
    CIR, Laboratory of Ophthalmology, University Campus Bio Medico, Rome, Italy
    Mol Vis 15:2037-44. 2009
    ..To investigate if nerve growth factor (NGF) might modulate toll-like receptor (TLR) 4 and 9 expression in primary cultures of vernal keratoconjunctivitis (VKC)-derived conjunctival epithelial cells (VKC-ECs)...
  16. ncbi request reprint Nerve growth factor effect on human primary fibroblastic-keratocytes: possible mechanism during corneal healing
    Alessandra Micera
    CIR Laboratory of Ophthalmology, University Campus Bio Medico and G B Bietti, Foundation, Via Emilio Longoni 83, 00155 Rome, Italy
    Exp Eye Res 83:747-57. 2006
    ..To sum up, the findings of this study indicate that NGF can modulate some functional activities of fibroblastic-keratocytes, thus substantiating the healing effects of NGF on corneal wound-healing...
  17. ncbi request reprint Topical treatment with nerve growth factor in an animal model of herpetic keratitis
    Alessandro Lambiase
    Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University Campus Bio Medico of Rome, Via E Longoni, 83 00155, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 246:121-7. 2008
    ..The aims of this study were to evaluate the role of endogenous NGF in HSV corneal infection, and the effects of topical NGF treatment on herpetic keratitis...
  18. ncbi request reprint Alterations of tear neuromediators in dry eye disease
    Alessandro Lambiase
    Department of Ophthalmology, Campus Bio Medico, University of Rome, Italy
    Arch Ophthalmol 129:981-6. 2011
    ..To evaluate tear levels of neuromediators in patients with dry eye disease and to identify statistical correlations with the clinical findings...
  19. ncbi request reprint Efficacy of topical nerve growth factor treatment in dogs affected by dry eye
    Marco Coassin
    Laboratory of Ophthalmology, Interdisciplinary Center for Biomedical Research CIR, University Campus Bio Medico of Rome, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 243:151-5. 2005
    ..Preliminary data show that nerve growth factor (NGF) may improve tear production in humans. We evaluated the efficacy of topical NGF treatment in dogs who developed dry eye after the excision of the third eyelid lacrimal gland...
  20. ncbi request reprint Nerve growth factor modulates in vitro the expression and release of TGF-beta1 by amniotic membrane
    Marco Coassin
    Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University of Rome Campus Bio Medico, Via E Longoni, 83, 00155, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 244:485-91. 2006
    ..Thereafter, to evaluate in an in vitro model if increasing concentrations of NGF are able to stimulate AM to produce and release TGF-beta1...
  21. doi request reprint Human idiopathic epiretinal membranes express NGF and NGF receptors
    Simona Minchiotti
    IRCCS G B Bietti Eye Foundation, Rome, Italy
    Retina 28:628-37. 2008
    ..Therefore, the authors evaluated myoFBs in ERMs and NGF, trkA(NGFR and p75(NTR) expression, as well as TGF-beta1/TGF-betaRII levels in both ERMs and vitreous...
  22. ncbi request reprint Preliminary evidence of the efficacy of probiotic eye-drop treatment in patients with vernal keratoconjunctivitis
    Alfonso Iovieno
    Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University of Rome Campus Bio Medico, Via E Longoni, 83, 00155, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 246:435-41. 2008
    ..Probiotics have been shown to improve allergic inflammation. The aim of this study was to evaluate the efficacy of Lactobacillus Acidophilus eye-drops in controlling signs and symptoms of vernal keratoconjunctivitis (VKC)...
  23. doi request reprint Ocular surface damage by ophthalmic compounds
    Flavio Mantelli
    Department of Ophthalmology, Campus Bio Medico, University of Rome, Rome, Italy
    Curr Opin Allergy Clin Immunol 11:464-70. 2011
    ..To describe the changes of the ocular surface following chronic use of eye drop therapies. The possible pathogenetic mechanisms responsible for specific signs and symptoms are described and discussed...
  24. doi request reprint Capsaicin-induced corneal sensory denervation and healing impairment are reversed by NGF treatment
    Alessandro Lambiase
    Department of Ophthalmology, Campus Bio Medico University of Rome, Rome, Italy
    Invest Ophthalmol Vis Sci 53:8280-7. 2012
    ..We aimed to evaluate the nerve growth factor (NGF) pathway and its influence on corneal healing mechanisms in normal conditions and in an animal model of corneal denervation induced by capsaicin...
  25. ncbi request reprint In vivo characterization of doxycycline effects on tear metalloproteinases in patients with chronic blepharitis
    Alfonso Iovieno
    Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University of Roma Campus Bio Medico, Roma Italy
    Eur J Ophthalmol 19:708-16. 2009
    ..It has been shown in vitro that doxycycline inhibits MMPs activation. The aim of this study was to investigate in vivo the effect of doxycycline in modulating MMPs in patients with chronic idiopathic blepharitis...
  26. ncbi request reprint Conjunctival expression of thymosin-beta4 in vernal keratoconjunctivitis
    Alessandra Micera
    Istituto di Ricovero e Cura a Carattere Scientifico Gian Battista Bietti Eye Foundation and CIR, Laboratory of Ophthalmology, University Campus Bio Medico, Rome, Italy
    Mol Vis 12:1594-600. 2006
    ....
  27. ncbi request reprint Nerve growth factor eye drop administrated on the ocular surface of rodents affects the nucleus basalis and septum: biochemical and structural evidence
    Alessandro Lambiase
    Department of Ophthalmology, University Campus Bio Medico, G B Bietti Eye Foundation, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy
    Brain Res 1127:45-51. 2007
    ..The present findings suggest that eye NGF application can represent an alternative route to prevent degeneration of NGF-receptive neurons involved in disorders such as Alzheimer and Parkinson...
  28. ncbi request reprint NGF topical application in patients with corneal ulcer does not generate circulating NGF antibodies
    Alessandro Lambiase
    Laboratory of Ophthalmology, CIR, University Campus Bio Medico, Rome, Italy
    Pharmacol Res 56:65-9. 2007
    ..None of the patients suffered any adverse reaction, except for mild and transient conjunctival hyperaemia and photophobia. Moreover, none of the treated patients developed circulating antibodies to NGF...
  29. ncbi request reprint Nerve growth factor involvement in the visual system: implications in allergic and neurodegenerative diseases
    Alessandra Micera
    CIR Laboratorio di Oftalmologia, Campus Bio Medico and Fondazione GB Bietti, Rome, Italy
    Cytokine Growth Factor Rev 15:411-7. 2004
    ..The present review of experimental and clinical studies will highlight old and recent strategies for treating ocular surface and tear disorders with NGF...
  30. pmc T-helper 17 lymphocytes in ocular cicatricial pemphigoid
    Alessandro Lambiase
    Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University of Rome, Rome, Italy
    Mol Vis 15:1449-55. 2009
    ..T-helper 17 lymphocytes (Th17) were identified in the healthy conjunctiva and in patients with ocular cicatricial pemphigoid (OCP), a disease characterized by chronic ocular surface inflammation...
  31. ncbi request reprint Nerve growth factor (NGF): an important molecule for trophism and healing of the ocular surface
    Stefano Bonini
    Department of Ophthalmology, University of Rome Tor Vergata and the G B Bietti Eye Foundation, CNR, Rome, Italy
    Adv Exp Med Biol 506:531-7. 2002
  32. doi request reprint Neurogenic inflammation of the ocular surface
    Flavio Mantelli
    Department of Ophthalmology, Campus Bio Medico University of Rome, Rome, Italy
    Curr Opin Allergy Clin Immunol 10:498-504. 2010
    ....
  33. pmc Chronic nerve growth factor exposure increases apoptosis in a model of in vitro induced conjunctival myofibroblasts
    Alessandra Micera
    IRCCS G B Bietti Foundation, Rome, Italy
    PLoS ONE 7:e47316. 2012
    ..Due to the lack of effective pharmacological agents for balanced tissue repairs, these new findings suggest that NGF might be a suitable therapeutic tool in conditions with impaired tissue healing...
  34. doi request reprint Tailored approach to the treatment of vernal keratoconjunctivitis
    Marta Sacchetti
    Department of Ophthalmology, University of Rome, Campus Bio Medico, Rome, Italy
    Ophthalmology 117:1294-9. 2010
    ....
  35. doi request reprint Toll-like receptors in ocular surface diseases: overview and new findings
    Alessandro Lambiase
    Department of Ophthalmology, University of Rome Campus Bio Medico, Via Alvaro del Portillo, 21, 00128 Rome, Italy
    Clin Sci (Lond) 120:441-50. 2011
    ..The purpose of the present review is to summarize the current knowledge of TLRs at the ocular surface and to propose them as potential targets of therapy for ocular inflammatory conditions...
  36. ncbi request reprint Clinical and cytological findings in limbal stem cell deficiency
    Marta Sacchetti
    Interdisciplinary Center for Biomedical Research CIR Laboratory of Ophthalmology, University of Rome Campus Bio Medico, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 243:870-6. 2005
    ..To evaluate and relate the clinical (including corneal sensitivity and tear function) and cytological (presence of goblet cells and cytokeratin 3- and 19-positive cells) features of limbal stem cell deficiency (LSCD)...
  37. ncbi request reprint Natural killer cells in vernal keratoconjunctivitis
    Alessandro Lambiase
    Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University Campus Bio Medico of Rome, Italy
    Mol Vis 13:1562-7. 2007
    ..The aim of this study was to evaluate NK in the blood and the conjunctiva of patients with vernal keratoconjunctivitis (VKC)...
  38. ncbi request reprint Toxic corneal ulcer: a frequent and sight-threatening disease
    Marta Sacchetti
    Department of Ophthalmology, University of Rome Campus Bio Medico, Rome Italy
    Eur J Ophthalmol 19:916-22. 2009
    ..This study aimed to investigate the clinical and visual impact of toxic corneal ulcers and the management and risk factors for their development and outcomes...
  39. doi request reprint The cellular mechanisms of dry eye: from pathogenesis to treatment
    Flavio Mantelli
    IRCCS Fondazione GB Bietti of Rome, Rome, Italy
    J Cell Physiol 228:2253-6. 2013
    ..J. Cell. Physiol. 228: 2253-2256, 2013. © 2013 Wiley Periodicals, Inc. ..
  40. ncbi request reprint Hyperosmolar conjunctival provocation for the evaluation of nonspecific hyperreactivity in healthy patients and patients with allergy
    Marta Sacchetti
    Department of Ophthalmology, University of Rome, Campus Bio Medico, Italy
    J Allergy Clin Immunol 118:872-7. 2006
    ..Tissue hyperreactivity of target organs to nonspecific stimuli is known to be an important factor in influencing the clinical picture of allergic disease...
  41. ncbi request reprint Topical azithromycin as a novel treatment for ocular rosacea
    Flavio Mantelli
    IRCCS Fondazione Bietti, Rome, Italy
    Ocul Immunol Inflamm 21:371-7. 2013
    ..Current treatments include artificial tears, lid hygiene, and systemic doxycycline. In this study the authors evaluate the effectiveness of topical azithromycin in ocular rosacea...
  42. doi request reprint The role of neuromediators in ocular allergy
    Alessandra Micera
    CIR Laboratory of Ophthalmology, Bietti Eye Foundation, University Campus Bio Medico, Italy
    Curr Opin Allergy Clin Immunol 8:466-71. 2008
    ....
  43. doi request reprint Clinical applications of NGF in ocular diseases
    Alessandro Lambiase
    Department of Ophthalmology, Campus Bio Medico University of Rome, Italy
    Arch Ital Biol 149:283-92. 2011
    ....
  44. ncbi request reprint MUC5AC overexpression in tear film of neonates
    Flavio Mantelli
    Interdisciplinary Center for Biomedical Research Laboratory of Ophthalmology, Campus Bio Medico University of Rome, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 245:1377-81. 2007
    ..However, tear-film stability is not only based on the integrity of the lipid layer, but also reflects properties of the underlying mucus layer. Characteristics of the neonatal mucus tear-film layer have not yet been described...
  45. doi request reprint Corneal changes in neurosurgically induced neurotrophic keratitis
    Alessandro Lambiase
    Department of Ophthalmology, University of Rome, Campus Bio Medico, Rome, Italy
    JAMA Ophthalmol 131:1547-53. 2013
    ..Neurotrophic keratitis (NK) represents a sight-threatening complication after trigeminal impairment. To our knowledge, the duration for which trigeminal injury may affect corneal structures and function has not been investigated previously...
  46. ncbi request reprint Preservative-free diclofenac sodium 0.1% for vernal keratoconjunctivitis
    Gennaro D'Angelo
    Department of Ophthalmology, University of Rome Tor Vergata, Via Moscati 31, Italy
    Graefes Arch Clin Exp Ophthalmol 241:192-5. 2003
    ..The aim of this study is to evaluate the efficacy of prolonged treatment with preservative-free diclofenac sodium 0.1% eye drops in patients with vernal keratoconjunctivitis (VKC)...
  47. ncbi request reprint Montelukast, a leukotriene receptor antagonist, in vernal keratoconjunctivitis associated with asthma
    Alessandro Lambiase
    Interdisciplinary Research Center, University Campus Bio Medico, Laboratory of Ophthalmology, Rome, Italy
    Arch Ophthalmol 121:615-20. 2003
    ..To evaluate the effects on signs and symptoms of a coexisting vernal keratoconjunctivitis in patients treated with oral montelukast sodium for asthma...
  48. ncbi request reprint Nerve growth factor in Behçet's disease
    Massimo Accorinti
    Servizio di Immunovirologia Oculare, Universita di Roma La Sapienza, Rome, Italy
    Adv Exp Med Biol 528:283-5. 2003
  49. doi request reprint Nerve growth factor eye drops to treat glaucoma
    Alessandro Lambiase
    Department of Ophthalmology, University of Rome Campus Bio Medico, Rome, Italy
    Drug News Perspect 23:361-7. 2010
    ..The pharmacological activity of NGF eye drops in ocular surface, retina and optic nerve diseases are also discussed...
  50. ncbi request reprint Therapeutic effect of topical 5-fluorouracil in conjunctival squamous carcinoma is associated with changes in matrix metalloproteinases and tissue inhibitor of metalloproteinases expression
    Alfonso Iovieno
    Department of Ophthalmology, University Campus Bio Medico, 00128 Rome, Italy
    Cornea 28:821-4. 2009
    ....
  51. doi request reprint Multiple action agents and the eye: do they really stabilize mast cells?
    Alessandro Lambiase
    CIR Laboratory of Ophthalmology, University Campus Bio Medico, Italy
    Curr Opin Allergy Clin Immunol 9:454-65. 2009
    ..This pharmaceutical class is, therefore, rapidly becoming the first choice for prevention and treatment for allergic conjunctivitis...
  52. ncbi request reprint Nerve growth factor and the immune system: old and new concepts in the cross-talk between immune and resident cells during pathophysiological conditions
    Alessandro Lambiase
    CIR Ophthalmology Laboratory, Campus Bio Medico and G B Bietti Eye Foundation, and San Raffaele H Research, Rome, Italy
    Curr Opin Allergy Clin Immunol 4:425-30. 2004
    ..Furthermore, recent data are provided revealing new important insights into the mechanisms of action of nerve growth factor in allergic reaction...
  53. ncbi request reprint Development and testing of the quality of life in children with vernal keratoconjunctivitis questionnaire
    Marta Sacchetti
    Department of Ophthalmology, University of Rome Campus Bio Medico, Rome, Italy
    Am J Ophthalmol 144:557-63. 2007
    ..To develop and validate a questionnaire that measures health-related quality of life (HRQoL) in children with vernal keratoconjunctivitis (VKC)...
  54. ncbi request reprint Cytokines in ocular allergy
    Stefano Bonini
    Institute of Neurobiology and Molecular Medicine, National Research Council, Rome, Italy
    Int Ophthalmol Clin 43:27-32. 2003
  55. doi request reprint Molecular and biochemical expression of TLRs in human amniotic membrane: a comparative study of fresh and cryopreserved specimens
    Alessandra Micera
    IRCCS G B Bietti Foundation, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 252:267-74. 2014
    ..To assess the expression of toll-like receptors (TLRs) in human amniotic membrane (AM) specimens and compare this expression with those of AMs undergoing the standard preservation procedure (handling) for ocular surgery...
  56. ncbi request reprint Intraocular production and release of nerve growth factor after iridectomy
    Alessandro Lambiase
    Department of Ophthalmology, University of Rome Tor Vergata, Rome, Italy
    Invest Ophthalmol Vis Sci 43:2334-40. 2002
    ..To determine the presence of nerve growth factor (NGF), NGF mRNA, and NGF receptor (TrkA) in rabbit ocular tissues, and whether changes occur in NGF and NGF mRNA levels after experimental iridectomy...
  57. doi request reprint Nerve growth factor therapy for corneal disease
    Alessandro Lambiase
    Department of Ophthalmology, University of Rome Campus Bio Medico, Via Alvarodel Portillo 200, Rome, Italy
    Curr Opin Ophthalmol 23:296-302. 2012
    ..To review the experimental and clinical data on the effects of nerve growth factor (NGF) in corneal physiopathology and to discuss the future development of NGF therapy for corneal diseases...
  58. doi request reprint A simple and rapid diagnostic algorithm for the detection of ocular allergic diseases
    Flavio Mantelli
    Department of Ophthalmology, Campus Bio Medico University of Rome, Italy
    Curr Opin Allergy Clin Immunol 9:471-6. 2009
    ....
  59. doi request reprint Prospective, multicenter demographic and epidemiological study on vernal keratoconjunctivitis: a glimpse of ocular surface in Italian population
    Alessandro Lambiase
    Department of Ophthalmology, University Campus Bio Medico, Rome, Italy
    Ophthalmic Epidemiol 16:38-41. 2009
    ..To evaluate the frequency and epidemiological features of vernal keratoconjunctivitis (VKC) in Italy...
  60. ncbi request reprint Allergic chronic inflammation of the ocular surface in vernal keratoconjunctivitis
    Stefano Bonini
    Interdisciplinary Center for Biomedical Research CIR Laboratory of Ophthalmology, University of Rome Campus Bio Medico, and G B Bietti Eye Foundation, Italy
    Curr Opin Allergy Clin Immunol 3:381-7. 2003
    ....
  61. ncbi request reprint Topical treatment of pressure ulcers with nerve growth factor: a randomized clinical trial
    Francesco Landi
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Ann Intern Med 139:635-41. 2003
    ..Management options for pressure ulcers include local wound care; surgical repair; and, more recently, topical application of growth factors...
  62. ncbi request reprint Demographic and clinical factors associated with development of brimonidine tartrate 0.2%-induced ocular allergy
    Gianluca Manni
    University of Rome Tor Vergata, Department of Ophthalmology, Italy
    J Glaucoma 13:163-7. 2004
    ..To identify demographic and clinical characteristics associated with the development of brimonidine tartrate 0.2%-induced ocular allergy...
  63. doi request reprint Management of porous orbital implants requiring explantation: a clinical and histopathological study
    Francesco M Quaranta-Leoni
    Orbital and Adnexal Service, Department of Ophthalmology, Department of Pathology, Villa Tiberia Hospital, Via Emilio Praga and Department of Ophthalmology, Campus Bio Medico University of Rome, Via Alvaro del Portillo, Roma, Italy
    Ophthal Plast Reconstr Surg 30:132-6. 2014
    ..To perform a histopathological review of exposed porous orbital implants requiring explantation and to study the clinical outcome of replacement of the exposed implant with an autologous dermis-fat graft...
  64. doi request reprint The anti-inflammatory effects of therapies for ocular allergy
    Flavio Mantelli
    1 IRCCS Fondazione Bietti, Rome, Italy
    J Ocul Pharmacol Ther 29:786-93. 2013
    ....
  65. doi request reprint Is visual function affected in severe ocular allergies?
    Andrea Leonardi
    Ophthalmology Unit, Department of Neuroscience, University of Padua, Padua, Italy
    Curr Opin Allergy Clin Immunol 13:558-62. 2013
    ..Furthermore, different treatment options are discussed based on the sight-threatening effects of corticosteroid use...
  66. ncbi request reprint Effect of exogenous administration of nerve growth factor in the retina of rats with inherited retinitis pigmentosa
    Laura Lenzi
    Institute of Neurobiology and Molecular Medicine, Neurobiology Section, CNR, Viale Marx 43 15, 00137 Rome, Italy
    Vision Res 45:1491-500. 2005
    ..This suggests that NGF has an effect on RCS rat retina, probably also through the stimulation of other biological mediators produced and released in the retina...
  67. ncbi request reprint Chemokine receptor CCR5 expression in conjunctival epithelium of patients with dry eye syndrome
    Abha Gulati
    Schepens Eye Research Institute, 20 Staniford Street, Boston, MA 02114, USA
    Arch Ophthalmol 124:710-6. 2006
    ..To characterize chemokine receptor CCR5 expression on the conjunctival epithelium in dry eye syndromes...
  68. ncbi request reprint Nerve growth factor and tissue repair remodeling: trkA(NGFR) and p75(NTR), two receptors one fate
    Alessandra Micera
    Department of Pharmacology, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel
    Cytokine Growth Factor Rev 18:245-56. 2007
    ..In summary, these novel findings on the potential pro-healing capacity of NGF might open new possibilities for this growth factor in modulating the healing processes in several pathological conditions...
  69. ncbi request reprint Limbal stem cell deficiency associated with LADD syndrome
    Magdalena Cortes
    G B Bietti Eye Foundation, Via Livenza 3, 00196 Rome, Italy
    Arch Ophthalmol 123:691-4. 2005