L Bonavina

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..Long-term outcomes and predictors of success after transoral stapling for Zenker diverticulum are still unclear...

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..Mediastinal drainage and ligation of the cisterna chyli and the thoracic duct was successfully performed through a transhiatal approach...

..In non-responding patients salvage surgery improves survival, especially if complete resection is achieved...

..Furthermore, this approach involves long intensive care unit stay, in-hospital stay and long recovery period. Minimally invasive esophagectomy could reduce the morbidity and accelerate the post-operative recovery...

..Chemoradiation therapy should be the first-line approach in patients with locally advanced tumors. A pathological complete response to neoadjuvant therapy is associated with a significantly improved long-term survival...

..To the best of our knowledge, this is the first case in which a bronchoesophageal fistula developed after successful endovascular repair of aortoesophageal fistula. The pathogenesis of this complications remains unclear...

..Benign esophageal pseudoachalasia is a rare condition...

..To assess the effectiveness of minimally invasive versus traditional open surgical approach in the treatment of Zenker diverticulum...

..The Magnetic Sphincter Augmentation device has been designed to augment the lower esophageal sphincter barrier using magnetic force. A multi-center feasibility trial was done to evaluate safety and efficacy...

..Use of a laparoscopic needle holder allowed to repair the supradiaphragmatic aorta through a laparotomy without the need of patient repositioning for a transthoracic approach...

..The method proved to be simple, reproducible, and not expensive. Unified standards for specimen collection are necessary to improve results of specimen-based diagnostic testing and research in surgical oncology...

..gov registration numbers NCT01057992, NCT01058070, and 01058564) to assess the safety and efficacy of a laparoscopically implanted sphincter augmentation device for the treatment of gastroesophageal reflux disease (GERD)...

..Compared to the laparoscopic total esophagectomy, this approach provides a more controlled and safer dissection of the upper mediastinum...

..In addition, by means of laparoscopic techniques, it is possible to mobilize the stomach and perform a safe transhiatal mediastinal dissection at least up to the level of the inferior pulmonary veins...

..Neoadjuvant therapy requires major improvement before it can be unconditionally recommended outside clinical trials...

..In fact, the postoperative mortality and long-term survival rates of elderly patients undergoing resection are comparable to that of younger individuals...

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..01 vs normal veins). These results suggest that dilatation of the varicose vein wall may be related to some defect of elastin metabolism. Further studies on the metabolic activity of vein muscle cells are required...

..Chylothorax is a relatively uncommon complication of esophageal surgery that may lead to severe respiratory, nutritional, and immunologic deficiencies...

..01). CONCLUSION: Endoscopic surveillance of Barrett's esophagus provides early detection of malignant degeneration and a better long-term survival than in nonsurveyed patients...

..Today, in the absence of randomized trials, the choice between surgery and definitive chemoradiotherapy should be based on clear information and the patient's preference. Salvage surgery is feasible and effective in selected patients...

..For this reason, we recommend that this technique should be done only in specialized centres and that these patients continue their endoscopic surveillance program...

..This finding supports the extension of the myotomy to the muscularis propria of the esophagus below the CPM. The alterated Ides to Des ratio suggests a primary disease of CPM as a cause of Zenker's diverticulum...

..To identify bronchoscopic findings that predict resectability of squamous cell carcinoma of the upper thoracic esophagus...

..Some of them precede the development of intestinal metaplasia, suggesting that genetic alterations take place earlier than previously thought...

..It provides superior information (intraoperative histologic confirmation) for the diagnosis and pretreatment staging of HCC in patients with cirrhosis when compared with current radiologic imaging techniques...

..However, the prognostic and therapeutic implications of this finding need further investigation...

..Early detection of Crohn's disease may decrease the incidence of acute life-threatening complications provided that appropriate medical treatment is administered and a multidisciplinary approach is offered to these patients...

..These results suggest that nuclear accumulation of MBNL1 and ribonuclear inclusions may have a direct adverse effect on gallbladder smooth muscle contractility and thus contribute to gallstones formation in DM1 patients...

..To compare 2 different types of covered esophageal nitinol stents (Ultraflex and Choostent) in terms of efficacy, complications, and long-term outcome...

..Major efforts should be undertaken to identify patients before neoadjuvant treatments who are likely to respond...

..The importance of an accurate diagnostic work-up is emphasized. Esophagectomy and chemotherapy followed by bone marrow transplantation allowed a complete response and the long-term survival of the patient...