M Bonamico

Summary

Affiliation: University of Rome La Sapienza
Country: Italy

Publications

  1. ncbi request reprint Prevalence and clinical picture of celiac disease in italian down syndrome patients: a multicenter study
    M Bonamico
    Department of Paediatrics, La Sapienza University, Rome, Italy
    J Pediatr Gastroenterol Nutr 33:139-43. 2001
  2. ncbi request reprint Antiendomysial antibody detection in biopsy culture allows avoidance of gluten challenge in celiac children
    Margherita Bonamico
    Department of Pediatrics and Department of Clinical Sciences, University of Rome La Sapienza, Viale Regina Elena 324, 00161, Rome, Italy
    J Pediatr Gastroenterol Nutr 40:165-9; discussion 122-4. 2005
  3. ncbi request reprint Serologic and genetic markers of celiac disease: a sequential study in the screening of first degree relatives
    Margherita Bonamico
    Department of Pediatrics, University of Rome La Sapienza, Viale Regina Elena 324, 00161 Rome, Italy
    J Pediatr Gastroenterol Nutr 42:150-4. 2006
  4. ncbi request reprint Tissue transglutaminase autoantibody detection in human saliva: a powerful method for celiac disease screening
    Margherita Bonamico
    Institute of Paediatrics and Department of Clinical Science, University of Rome La Sapienza, Italy
    J Pediatr 144:632-6. 2004
  5. ncbi request reprint Duodenal bulb biopsies in celiac disease: a multicenter study
    Margherita Bonamico
    Department of Paediatrics, University La Sapienza of Rome, Rome, Italy
    J Pediatr Gastroenterol Nutr 47:618-22. 2008
  6. ncbi request reprint Radioimmunological detection of anti-transglutaminase autoantibodies in human saliva: a useful test to monitor coeliac disease follow-up
    M Bonamico
    Department of Paediatrics, Sapienza University of Rome, Rome, Italy
    Aliment Pharmacol Ther 28:364-70. 2008
  7. doi request reprint First salivary screening of celiac disease by detection of anti-transglutaminase autoantibody radioimmunoassay in 5000 Italian primary schoolchildren
    Margherita Bonamico
    Departments of Paediatrics, La Sapienza University of Rome, Italy
    J Pediatr Gastroenterol Nutr 52:17-20. 2011
  8. ncbi request reprint Celiac disease and lamellar ichthyosis. Case study analysis and review of the literature
    Raffaella Nenna
    Department of Pediatrics, I Faculty, Sapienza University of Rome, Italy
    Acta Dermatovenerol Croat 19:268-70. 2011
  9. ncbi request reprint Patchy villous atrophy of the duodenum in childhood celiac disease
    Margherita Bonamico
    Department of Pediatrics, University of Rome La Sapienza, Rome, Italy
    J Pediatr Gastroenterol Nutr 38:204-7. 2004
  10. ncbi request reprint Evidence of a selective epitope loss of anti-transglutaminase immunoreactivity in gluten-free diet celiac sera: a new tool to distinguish disease-specific immunoreactivities
    C Tiberti
    Dept of Clinical Sciences, University of Rome La Sapienza, Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, Italy
    Clin Immunol 121:40-6. 2006

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Prevalence and clinical picture of celiac disease in italian down syndrome patients: a multicenter study
    M Bonamico
    Department of Paediatrics, La Sapienza University, Rome, Italy
    J Pediatr Gastroenterol Nutr 33:139-43. 2001
    ..A multicenter research study of Down syndrome patients was carried out to estimate the prevalence of celiac disease in patients with Down syndrome and to show clinical characteristics and laboratory data of Down syndrome patients...
  2. ncbi request reprint Antiendomysial antibody detection in biopsy culture allows avoidance of gluten challenge in celiac children
    Margherita Bonamico
    Department of Pediatrics and Department of Clinical Sciences, University of Rome La Sapienza, Viale Regina Elena 324, 00161, Rome, Italy
    J Pediatr Gastroenterol Nutr 40:165-9; discussion 122-4. 2005
    ..The aim of the present study was to use this in vitro system to determine whether it could be used to predict the clinical or histologic relapse to gluten challenge in CD children on a gluten-free diet (GFD)...
  3. ncbi request reprint Serologic and genetic markers of celiac disease: a sequential study in the screening of first degree relatives
    Margherita Bonamico
    Department of Pediatrics, University of Rome La Sapienza, Viale Regina Elena 324, 00161 Rome, Italy
    J Pediatr Gastroenterol Nutr 42:150-4. 2006
    ..The prevalence of celiac disease (CD) among the relatives and the complications of an undiagnosed CD prompted us to identify a useful disease screening strategy...
  4. ncbi request reprint Tissue transglutaminase autoantibody detection in human saliva: a powerful method for celiac disease screening
    Margherita Bonamico
    Institute of Paediatrics and Department of Clinical Science, University of Rome La Sapienza, Italy
    J Pediatr 144:632-6. 2004
    ..To test the possibility of detecting tissue transglutaminase autoantibodies (tTG-Abs) in saliva with a novel sensitive fluid-phase radioimmunoassay (RIA)...
  5. ncbi request reprint Duodenal bulb biopsies in celiac disease: a multicenter study
    Margherita Bonamico
    Department of Paediatrics, University La Sapienza of Rome, Rome, Italy
    J Pediatr Gastroenterol Nutr 47:618-22. 2008
    ....
  6. ncbi request reprint Radioimmunological detection of anti-transglutaminase autoantibodies in human saliva: a useful test to monitor coeliac disease follow-up
    M Bonamico
    Department of Paediatrics, Sapienza University of Rome, Rome, Italy
    Aliment Pharmacol Ther 28:364-70. 2008
    ..Serum radioimmunoassay (RIA) tissue transglutaminase autoantibodies (tTG-Abs) proved to be a sensitive test also during coeliac disease (CD) follow-up. We demonstrated that RIA tTG-Abs could be detected in human saliva...
  7. doi request reprint First salivary screening of celiac disease by detection of anti-transglutaminase autoantibody radioimmunoassay in 5000 Italian primary schoolchildren
    Margherita Bonamico
    Departments of Paediatrics, La Sapienza University of Rome, Italy
    J Pediatr Gastroenterol Nutr 52:17-20. 2011
    ..The aim was to identify CD in 6- to 8-year-old children for a timely diagnosis, start gluten-free diet (GFD) in compliant subjects, achieve the growth target, and prevent CD complications...
  8. ncbi request reprint Celiac disease and lamellar ichthyosis. Case study analysis and review of the literature
    Raffaella Nenna
    Department of Pediatrics, I Faculty, Sapienza University of Rome, Italy
    Acta Dermatovenerol Croat 19:268-70. 2011
    ..After 1-year follow-up, the girl showed complete normalization of bone mineral density. The introduction of the gluten-free diet did not lead to lesion repair, but the child reported significant improvement of her quality of life...
  9. ncbi request reprint Patchy villous atrophy of the duodenum in childhood celiac disease
    Margherita Bonamico
    Department of Pediatrics, University of Rome La Sapienza, Rome, Italy
    J Pediatr Gastroenterol Nutr 38:204-7. 2004
    ..The authors evaluated the presence and the distribution of villous atrophy in children with celiac disease to see whether this histologic pattern exists in children...
  10. ncbi request reprint Evidence of a selective epitope loss of anti-transglutaminase immunoreactivity in gluten-free diet celiac sera: a new tool to distinguish disease-specific immunoreactivities
    C Tiberti
    Dept of Clinical Sciences, University of Rome La Sapienza, Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, Italy
    Clin Immunol 121:40-6. 2006
    ....
  11. ncbi request reprint Oligotyping of Italian celiac patients with the 11th International Histocompatibility Workshop reagents
    P Ferrante
    Department of Experimental Medicine, University La Sapienza, Rome, Italy
    Tissue Antigens 39:38-9. 1992
    ..86). 7 patients (12.7%) were negative for the DQA1*0501/B1*0201 dimer: 3 of them were DR4 (5.4%) and the others typed as DR1,5; 1,7; 5,7 and w6,7. No patient was negative for both DQA1*0501 and DQB1*0201 alleles...
  12. ncbi request reprint Radioimmunoassay to detect antitransglutaminase autoantibodies is the most sensitive and specific screening method for celiac disease
    M Bonamico
    Istituto di Clinica Pediatrica, Dipartimento di Scienze Cliniche, Medicina Sperimentale e Patologia, , Rome, Italy
    Am J Gastroenterol 96:1536-40. 2001
    ..If our data are confirmed by studies on larger series, tissue transglutaminase RIA could be proposed as the best screening method for celiac patients...
  13. ncbi request reprint Different dose effect of HLA-DQ alpha beta heterodimers in insulin-dependent diabetes mellitus and celiac disease susceptibility
    F Petronzelli
    Department of Experimental Medicine, La Sapienza University, Rome, Italy
    Hum Immunol 36:156-62. 1993
    ....
  14. ncbi request reprint Celiac disease-associated transglutaminase autoantibody target domains at diagnosis are age and sex dependent
    C Tiberti
    Department of Clinical Sciences, University La Sapienza, Rome, Italy
    Clin Immunol 109:318-24. 2003
    ..Our data identify a subset of CD patients showing a strong humoral tTG immunoreactivity at diagnosis, thus suggesting that age and sex influence the anti-tTG autoantibody response...
  15. ncbi request reprint HLA antigens and antigliadin antibodies in coeliac disease
    M Bonamico
    I Clinica Pediatrica, , Rome, Italy
    Dis Markers 9:313-7. 1991
    ..The observation that coeliac children negative for DR3 and DR7 showed lower AGA levels is consistent with clinical and genetic heterogeneity of coeliac disease...
  16. ncbi request reprint Usefulness of endoscopic small intestinal biopsies in children with coeliac disease
    F M Magliocca
    Department of Experimental Medicine, Faculty of Medicine, University of Rome La Sapienza, Italy
    Ital J Anat Embryol 106:329-35. 2001
    ..In our opinion, small intestinal biopsies obtained via endoscopy are more reliable than the peroral capsule biopsies in order to identify patchy mucosal atrophy and could be very useful for a correct diagnosis in CD patients...
  17. doi request reprint Size and dynamics of mucosal and peripheral IL-17A+ T-cell pools in pediatric age, and their disturbance in celiac disease
    R La Scaleia
    Department of Experimental Medicine, Sapienza University, Rome, Italy
    Mucosal Immunol 5:513-23. 2012
    ....
  18. ncbi request reprint CTLA-4 +49 A/G dimorphism in Italian patients with celiac disease
    Barbara Mora
    Department of Experimental Medicine and Pathology, Institute of Clinical Pediatrics, University of Rome La Sapienza, Italy
    Hum Immunol 64:297-301. 2003
    ..These data support CTLA-4 as a predisposing gene for CD in an Italian population with a prominent role in patients not carrying the high-risk human leukocyte antigen-DQ2 molecules...
  19. doi request reprint HLA-DQB1*02 dose effect on RIA anti-tissue transglutaminase autoantibody levels and clinicopathological expressivity of celiac disease
    Raffaella Nenna
    Departments of Paediatrics, Sapienza University, Rome, Italy
    J Pediatr Gastroenterol Nutr 47:288-92. 2008
    ..Our aim was to investigate whether the DQB1*02 allele could influence tTGAb titers and the clinicopathological expressivity of the disease...
  20. doi request reprint Long-term effects of Helicobacter pylori eradication on circulating ghrelin and leptin concentrations and body composition in prepubertal children
    Lucia Pacifico
    Department of Pediatrics, La Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy
    Eur J Endocrinol 158:323-32. 2008
    ..This finding raises the possibility that the infection might affect growth in children by reducing the ghrelin production...
  21. ncbi request reprint Body composition in coeliac disease adolescents on a gluten-free diet: a longitudinal study
    M C Carbone
    Institute of Paediatrics, University of La Sapienza Policlinico Umberto I, Viale Regina Elena 324, I 00161, Rome, Italy
    Acta Diabetol 40:S171-3. 2003
    ..005). In conclusion, our study demonstrates that adolescence is a period where some parameters of body composition can still be recovered...
  22. doi request reprint HLA-DQ and susceptibility to celiac disease: evidence for gender differences and parent-of-origin effects
    Francesca Megiorni
    Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
    Am J Gastroenterol 103:997-1003. 2008
    ....
  23. ncbi request reprint Association of the matrix metalloproteinase-3 (MMP-3) promoter polymorphism with celiac disease in male subjects
    Barbara Mora
    Department of Experimental Medicine and Pathology, University of Rome La Sapienza, Rome, Italy
    Hum Immunol 66:716-20. 2005
    ..Homozygosity for the 6A allele appears as a risk factor for CD only in men, which is different from the HLA susceptibility alleles that confer a higher risk in women...
  24. ncbi request reprint Search for coeliac disease susceptibility loci on 7q11.23 candidate region: absence of association with the ELN17 microsatellite marker
    R Grillo
    Department of Experimental Medicine, University of Rome La Sapienza, Rome, Italy
    Hum Hered 50:180-3. 2000
    ..The analysis of 74 Italian CD families provided no evidence of association with the ELN17 marker...
  25. doi request reprint HLA-DQ and risk gradient for celiac disease
    Francesca Megiorni
    Department of Experimental Medicine, Sapienza University of Rome, Italy
    Hum Immunol 70:55-9. 2009
    ..Those siblings and parents with no susceptible factors were not affected. These findings indicate the impact of the HLA test for CD in clinical practice...
  26. ncbi request reprint A rapid and sensitive method to detect specific human lymphocyte antigen (HLA) class II alleles associated with celiac disease
    Francesca Megiorni
    Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
    Clin Chem Lab Med 46:193-6. 2008
    ....
  27. ncbi request reprint Prevalence and clinical picture of celiac disease in Turner syndrome
    Margherita Bonamico
    Department of Pediatrics, University of Rome La Sapienza, 00161 Roma, Italy
    J Clin Endocrinol Metab 87:5495-8. 2002
    ..4%) of CD in a large series of TS patients. Moreover, the subclinical picture in 60% of the cases, the diagnostic delay, and the incidence of other autoimmune disorders suggest that routine screening of CD in TS is indicated...
  28. ncbi request reprint Analysis of candidate genes on chromosomes 5q and 19p in celiac disease
    Anna Latiano
    U O Gastroenterologia e Lab di Ricerca I R C C S Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
    J Pediatr Gastroenterol Nutr 45:180-6. 2007
    ..Additionally, any possible correlation with the HLA-DQ status was investigated. Finally, our data were pooled with the results of other studies by a meta-analysis...
  29. ncbi request reprint Which is the best screening test for celiac disease in Down syndrome children?
    Margherita Bonamico
    J Pediatr Gastroenterol Nutr 40:125-7. 2005
  30. ncbi request reprint Evaluation of stool antigen test, PCR on ORAL samples and serology for the noninvasive detection of Helicobacter pylori infection in children
    Margherita Bonamico
    Istituto di Clinica Pediatrica, Universita di Roma La Sapienza, Roma, Italy
    Helicobacter 9:69-76. 2004
    ..pylori stool antigen, the polimerase chain reaction for identification of bacterial DNA on the oral cavity and the serum specific antibodies...
  31. ncbi request reprint Autoimmune thyroid disease and celiac disease in children
    Nicoletta Ansaldi
    Azienda Ospedaliera O I R M S Anna, III Divisione Universitaria di Pediatria, Servizio di Gastroenterologia, Universita di Torino, Italy
    J Pediatr Gastroenterol Nutr 37:63-6. 2003
    ..The aim of this multicenter study was to establish the prevalence of autoimmune thyroid involvement in a large series of pediatric patients with CD...