G B Bolli

Summary

Affiliation: University of Perugia
Country: Italy

Publications

  1. ncbi Hypoglycaemia unawareness
    G B Bolli
    University of Perugia, Italy
    Diabetes Metab 23:29-35. 1997
  2. ncbi How to ameliorate the problem of hypoglycemia in intensive as well as nonintensive treatment of type 1 diabetes
    G B Bolli
    Department of Internal Medicine, Endocrinology and Metabolism, University of Perugia, Italy
    Diabetes Care 22:B43-52. 1999
  3. ncbi Physiology of glucose counterregulation to hypoglycemia
    G B Bolli
    Department of Internal Medicine, Endocrinology, and Metabolism, University of Perugia, Italy
    Endocrinol Metab Clin North Am 28:467-93, v. 1999
  4. ncbi Physiological insulin replacement in type 1 diabetes mellitus
    G B Bolli
    Department of Internal Medicine, University of Perugia, Italy
    Exp Clin Endocrinol Diabetes 109:S317-32. 2001
  5. ncbi Effect of the amino acid alanine on glucagon secretion in non-diabetic and type 1 diabetic subjects during hyperinsulinaemic euglycaemia, hypoglycaemia and post-hypoglycaemic hyperglycaemia
    F Porcellati
    Department of Internal Medicine, University of Perugia, Via E dal Pozzo, 06126, Perugia, Italy
    Diabetologia 50:422-30. 2007
  6. ncbi Better long-term glycaemic control with the basal insulin glargine as compared with NPH in patients with Type 1 diabetes mellitus given meal-time lispro insulin
    F Porcellati
    Section of Internal Medicine, Endocrinology and Metabolism, University of Perugia, Via E dal Pozzo, I 06126 Perugia, Italy
    Diabet Med 21:1213-20. 2004
  7. pmc Body weight, not insulin sensitivity or secretion, may predict spontaneous weight changes in nondiabetic and prediabetic subjects: the RISC study
    Eleni Rebelos
    Department of Internal Medicine, University of Pisa, Italy
    Diabetes 60:1938-45. 2011
  8. ncbi Recovery and prevention of hypoglycaemia unawareness in type 1 diabetes mellitus
    G B Bolli
    Department of Internal Medicine, University of Perugia, Perugia, Italy
    Diabetes Nutr Metab 15:402-9; discussion 409. 2002
  9. doi Lower fasting blood glucose, glucose variability and nocturnal hypoglycaemia with glargine vs NPH basal insulin in subjects with Type 1 diabetes
    G B Bolli
    Department of Internal Medicine, Endocrinology and Metabolism, University of Perugia, Italy
    Nutr Metab Cardiovasc Dis 19:571-9. 2009
  10. ncbi Rate of fall of blood glucose and physiological responses of counterregulatory hormones, clinical symptoms and cognitive function to hypoglycaemia in Type I diabetes mellitus in the postprandial state
    C G Fanelli
    University of Perugia, Department of Internal Medicine, Perugia, Italy
    Diabetologia 46:53-64. 2003

Collaborators

Detail Information

Publications27

  1. ncbi Hypoglycaemia unawareness
    G B Bolli
    University of Perugia, Italy
    Diabetes Metab 23:29-35. 1997
    ..Under these conditions, IDDM patients can maintain the warning symptoms and adrenaline response to hypoglycaemia, ensuring a vital backup system for safe intensive therapy of IDDM...
  2. ncbi How to ameliorate the problem of hypoglycemia in intensive as well as nonintensive treatment of type 1 diabetes
    G B Bolli
    Department of Internal Medicine, Endocrinology and Metabolism, University of Perugia, Italy
    Diabetes Care 22:B43-52. 1999
    ..Importantly, a program of meticulous prevention of hypoglycemia does not result in loss of long-term near-normoglycemia, i.e., it is compatible with the glycemic targets of intensive therapy...
  3. ncbi Physiology of glucose counterregulation to hypoglycemia
    G B Bolli
    Department of Internal Medicine, Endocrinology, and Metabolism, University of Perugia, Italy
    Endocrinol Metab Clin North Am 28:467-93, v. 1999
    ..The first response is known as counterregulation, a system that prevents and corrects hypoglycemia through the release of counterregulatory hormones...
  4. ncbi Physiological insulin replacement in type 1 diabetes mellitus
    G B Bolli
    Department of Internal Medicine, University of Perugia, Italy
    Exp Clin Endocrinol Diabetes 109:S317-32. 2001
    ..Insulin glargine reproduces closely the pharmacokinetics and pharmacodynamics of continuous s.c. insulin infusion, and should always be preferred to NPH in all insulin-requiring diabetic patients, both type 1 and type 2...
  5. ncbi Effect of the amino acid alanine on glucagon secretion in non-diabetic and type 1 diabetic subjects during hyperinsulinaemic euglycaemia, hypoglycaemia and post-hypoglycaemic hyperglycaemia
    F Porcellati
    Department of Internal Medicine, University of Perugia, Via E dal Pozzo, 06126, Perugia, Italy
    Diabetologia 50:422-30. 2007
    ..The aim of our study was to establish whether the well-known defective or absent secretion of glucagon in type 1 diabetes in response to hypoglycaemia is selective or includes lack of responses to other stimuli, such as amino acids...
  6. ncbi Better long-term glycaemic control with the basal insulin glargine as compared with NPH in patients with Type 1 diabetes mellitus given meal-time lispro insulin
    F Porcellati
    Section of Internal Medicine, Endocrinology and Metabolism, University of Perugia, Via E dal Pozzo, I 06126 Perugia, Italy
    Diabet Med 21:1213-20. 2004
    ..The aim of this study was to test superiority of glargine on long-term blood glucose (BG) as well as on responses to hypoglycaemia vs. NPH...
  7. pmc Body weight, not insulin sensitivity or secretion, may predict spontaneous weight changes in nondiabetic and prediabetic subjects: the RISC study
    Eleni Rebelos
    Department of Internal Medicine, University of Pisa, Italy
    Diabetes 60:1938-45. 2011
    ..Previous studies have found that high insulin sensitivity predicts weight gain; this association has not been confirmed. Our aim was to systematically analyze metabolic predictors of spontaneous weight changes...
  8. ncbi Recovery and prevention of hypoglycaemia unawareness in type 1 diabetes mellitus
    G B Bolli
    Department of Internal Medicine, University of Perugia, Perugia, Italy
    Diabetes Nutr Metab 15:402-9; discussion 409. 2002
  9. doi Lower fasting blood glucose, glucose variability and nocturnal hypoglycaemia with glargine vs NPH basal insulin in subjects with Type 1 diabetes
    G B Bolli
    Department of Internal Medicine, Endocrinology and Metabolism, University of Perugia, Italy
    Nutr Metab Cardiovasc Dis 19:571-9. 2009
    ..Secondary objectives included self-monitoring blood glucose, mean daily blood glucose (MDBG) and mean amplitude glucose excursion (MAGE) values alongside changes in HbA(1c) and safety profiles...
  10. ncbi Rate of fall of blood glucose and physiological responses of counterregulatory hormones, clinical symptoms and cognitive function to hypoglycaemia in Type I diabetes mellitus in the postprandial state
    C G Fanelli
    University of Perugia, Department of Internal Medicine, Perugia, Italy
    Diabetologia 46:53-64. 2003
    ..e. release of counterregulatory hormones, perception of symptoms, deterioration of cognitive function, and rates of forearm noradrenaline spillover, in the postprandial condition and in the sitting position...
  11. ncbi Glucagon: the effects of its excess and deficiency on insulin action
    C G Fanelli
    Department of Internal Medicine, Section of Endocrinology and Metabolism, University of Perugia, Via E dal Pozzo, I 06126 Perugia, Italy
    Nutr Metab Cardiovasc Dis 16:S28-34. 2006
    ..To review the role that glucagon plays in physiology, physiopathology and clinical medicine...
  12. ncbi Evaluation of the accuracy of a microdialysis-based glucose sensor during insulin-induced hypoglycemia, its recovery, and post-hypoglycemic hyperglycemia in humans
    P Rossetti
    Department of Internal Medicine, Endocrinology and Metabolism, University of Perugia, Perugia, Italy
    Diabetes Technol Ther 8:326-37. 2006
    ..Menarini Diagnostics, Firenze, Italy) compared with a standard reference method of plasma glucose measurement during insulin-induced hypoglycemia...
  13. ncbi Effects of whole-body vibration exercise on the endocrine system of healthy men
    C Di Loreto
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences IMISEM, University of Perugia, Perugia, Italy
    J Endocrinol Invest 27:323-7. 2004
    ..Since hormonal responses, with the exception of norepinephrine, are not affected by acute vibration exposure, this type of exercise is not expected to reduce fat mass in obese subjects...
  14. pmc Comparative pharmacodynamic and pharmacokinetic characteristics of subcutaneous insulin glulisine and insulin aspart prior to a standard meal in obese subjects with type 2 diabetes
    G B Bolli
    Department of Internal Medicine, University of Perugia, Perugia, Italy
    Diabetes Obes Metab 13:251-7. 2011
    ....
  15. ncbi Effect of sedentary behaviour and vigorous physical activity on segment-specific carotid wall thickness and its progression in a healthy population
    Michaela Kozakova
    Department of Internal Medicine, University of Pisa, Via Roma, 67, Pisa 56122, Italy
    Eur Heart J 31:1511-9. 2010
    ..This study investigated whether sedentary behaviour and different activity levels have an independent association with carotid intima-media thickness (IMT) and with the 3-year IMT progression in different carotid segments...
  16. ncbi Glargine metabolism over 24 h following its subcutaneous injection in patients with type 2 diabetes mellitus: A dose-response study
    P Lucidi
    Department of Internal Medicine, University of Perugia, Perugia, Italy
    Nutr Metab Cardiovasc Dis 24:709-16. 2014
    ..The present study was specifically designed to establish the dose-response metabolism of glargine over 24 h following s.c. injection in T2DM subjects on long-term use of glargine...
  17. doi Insulin sensitivity and beta-cell function in the offspring of type 2 diabetic patients: impact of line of inheritance
    Andrea Natali
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    J Clin Endocrinol Metab 95:4703-11. 2010
    ..What defects in glucose metabolism are present in offspring of type 2 diabetic patients (FHD(+) with a positive family history of diabetes) and to what extent they depend on line of inheritance are uncertain...
  18. doi Early insulin treatment in type 2 diabetes: ORIGINal sin or valuable choice as ORIGINal treatment? An open debate on the ORIGIN study results
    G B Bolli
    Clinica di Medicina Interna e Scienze Endocrine e Metaboliche, University of Perugia, Department of Medicine, Hospital Santa Maria della Misericordia, 06129 Sant Andrea delle Fratte, Perugia, Italy
    Nutr Metab Cardiovasc Dis 22:1007-12. 2012
    ..In these pages we invited two experienced scientists to freely argument their interpretation of the trial, aiming to help our understanding of the consequences of the ORIGIN trial on insulin therapy...
  19. ncbi Adrenaline vs glucagon in the primacy of glucose counterregulation
    P De Feo
    Department of Internal Medicine, University of Perugia, Perugia, Italy
    Diabetes Nutr Metab 15:323-7; discussion 328. 2002
  20. ncbi Lixisenatide, a novel GLP-1 receptor agonist: efficacy, safety and clinical implications for type 2 diabetes mellitus
    G B Bolli
    Department of Medicine, University of Perugia, Hospital S M della Misericordia, Perugia, Italy
    Diabetes Obes Metab 16:588-601. 2014
    ....
  21. doi The effect of menopause on carotid artery remodeling, insulin sensitivity, and plasma adiponectin in healthy women
    Elza Muscelli
    Department of Internal Medicine, University of Pisa, Pisa, Italy
    Am J Hypertens 22:364-70. 2009
    ....
  22. ncbi Basal-bolus insulin therapy in Type 1 diabetes: comparative study of pre-meal administration of a fixed mixture of insulin lispro (50%) and neutral protamine lispro (50%) with human soluble insulin
    M Herz
    Diabetes Product Team, Eli Lilly and Company, Indianapolis, IN, USA
    Diabet Med 19:917-23. 2002
    ..Both regimens included bedtime human isophane (NPH) insulin...
  23. ncbi Intensive insulin treatment in diabetic children
    J Ludvigsson
    Department of Health and Environment, , Sweden
    Diabetes Nutr Metab 14:292-304. 2001
    ..Thus, appropriate education should be delivered at diabetes onset to the child and parents in order to start the strategy of intensified insulin therapy as early as possible...
  24. ncbi Successful use of insulin glargine during entire pregnancy until delivery in six Type 1 diabetic women
    E Torlone
    Eur J Obstet Gynecol Reprod Biol 132:238-9. 2007
  25. ncbi Comparison of the effects of continuous subcutaneous insulin infusion (CSII) and NPH-based multiple daily insulin injections (MDI) on glycaemic control and quality of life: results of the 5-nations trial
    R P L M Hoogma
    Groene Hart Ziekenhuis, Gouda, The Netherlands
    Diabet Med 23:141-7. 2006
    ....
  26. ncbi Beyond the era of NPH insulin--long-acting insulin analogs: chemistry, comparative pharmacology, and clinical application
    D R Owens
    Diabetes Research Unit, Cardiff University, University Hospital Llandough, Penarth, United Kingdom
    Diabetes Technol Ther 10:333-49. 2008
    ....
  27. doi Influence of the ACE gene insertion/deletion polymorphism on insulin sensitivity and impaired glucose tolerance in healthy subjects
    Fabrice Bonnet
    Department of Medicine, Endocrinology Unit, Centre Hospitalier Universitaire, université Rennes, Rennes, France
    Diabetes Care 31:789-94. 2008
    ..The purpose of this study was to investigate the relationship between the ACE gene I/D polymorphism and both insulin sensitivity and glucose intolerance in a large cohort of healthy subjects...