U Boggi

Summary

Affiliation: University of Pisa
Country: Italy

Publications

  1. doi request reprint Surgical techniques for pancreas transplantation
    Ugo Boggi
    Division of General and Transplant Surgery in Uremic and Diabetic Patientss, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
    Curr Opin Organ Transplant 15:102-11. 2010
  2. doi request reprint Laparoscopic robot-assisted major hepatectomy
    Ugo Boggi
    Division of General and Transplant Surgery, Pisa University Hospital, Via Paradisa 2, Pisa, 56124, Italy
    J Hepatobiliary Pancreat Sci 21:3-10. 2014
  3. doi request reprint Feasibility of robotic pancreaticoduodenectomy
    U Boggi
    Division of General and Transplant Surgery, Pisa University Hospital, Pisa, Italy
    Br J Surg 100:917-25. 2013
  4. doi request reprint Follow-up of secondary diabetic complications after pancreas transplantation
    Ugo Boggi
    Division of General and Transplant Surgery, University of Pisa, Pisa, Italy
    Curr Opin Organ Transplant 18:102-10. 2013
  5. doi request reprint Transplantation of the pancreas
    Ugo Boggi
    Division of General and Transplant Surgery, Azienda Ospedaliera Universitaria Pisana, Universita di Pisa, Via Paradisa 2, 56124, Pisa, Italy
    Curr Diab Rep 12:568-79. 2012
  6. doi request reprint Central pancreatectomy with inframesocolic pancreatojejunostomy
    Ugo Boggi
    Division of General and Transplant Surgery, University of Pisa, Pisa, Italy
    Langenbecks Arch Surg 397:1013-21. 2012
  7. doi request reprint Long-term (5 years) efficacy and safety of pancreas transplantation alone in type 1 diabetic patients
    Ugo Boggi
    Division of General and Transplant Surgery in Uremic and Diabetic Patients, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
    Transplantation 93:842-6. 2012
  8. doi request reprint Laparoscopic robot-assisted pancreas transplantation: first world experience
    Ugo Boggi
    Division of General and Transplant Surgery, Pisa University Hospital, Pisa, Italy
    Transplantation 93:201-6. 2012
  9. ncbi request reprint Outcome of 118 pancreas transplants with retroperitoneal portal-enteric drainage
    U Boggi
    Division of Surgery in Uremic and Diabetic Patients, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
    Transplant Proc 37:2648-50. 2005
  10. ncbi request reprint Surveillance and rescue of pancreas grafts
    U Boggi
    Division of Surgery in Uremic and Diabetic Patients, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
    Transplant Proc 37:2644-7. 2005

Detail Information

Publications119 found, 100 shown here

  1. doi request reprint Surgical techniques for pancreas transplantation
    Ugo Boggi
    Division of General and Transplant Surgery in Uremic and Diabetic Patientss, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
    Curr Opin Organ Transplant 15:102-11. 2010
    ..The purpose of this review is to examine recent surgical advances and discuss their contribution to improved graft function...
  2. doi request reprint Laparoscopic robot-assisted major hepatectomy
    Ugo Boggi
    Division of General and Transplant Surgery, Pisa University Hospital, Via Paradisa 2, Pisa, 56124, Italy
    J Hepatobiliary Pancreat Sci 21:3-10. 2014
    ..We herein present a systematic review of English literature on robot-assisted major hepatectomy (MH)...
  3. doi request reprint Feasibility of robotic pancreaticoduodenectomy
    U Boggi
    Division of General and Transplant Surgery, Pisa University Hospital, Pisa, Italy
    Br J Surg 100:917-25. 2013
    ..The improved dexterity offered by robotic assistance provides the opportunity to see whether laparoscopic pancreaticoduodenectomy can be performed safely when faithfully reproducing the open operation...
  4. doi request reprint Follow-up of secondary diabetic complications after pancreas transplantation
    Ugo Boggi
    Division of General and Transplant Surgery, University of Pisa, Pisa, Italy
    Curr Opin Organ Transplant 18:102-10. 2013
    ..We herein review the available literature to define the impact of pancreas transplantation on chronic complications of diabetes mellitus...
  5. doi request reprint Transplantation of the pancreas
    Ugo Boggi
    Division of General and Transplant Surgery, Azienda Ospedaliera Universitaria Pisana, Universita di Pisa, Via Paradisa 2, 56124, Pisa, Italy
    Curr Diab Rep 12:568-79. 2012
    ..Refinements in graft preservation, surgical techniques, immunosuppression, and prophylactic treatments are expected to further improve the results of pancreas transplantation...
  6. doi request reprint Central pancreatectomy with inframesocolic pancreatojejunostomy
    Ugo Boggi
    Division of General and Transplant Surgery, University of Pisa, Pisa, Italy
    Langenbecks Arch Surg 397:1013-21. 2012
    ..The information could be obtained if the two pancreatic remnants were segregated into different body compartments...
  7. doi request reprint Long-term (5 years) efficacy and safety of pancreas transplantation alone in type 1 diabetic patients
    Ugo Boggi
    Division of General and Transplant Surgery in Uremic and Diabetic Patients, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
    Transplantation 93:842-6. 2012
    ....
  8. doi request reprint Laparoscopic robot-assisted pancreas transplantation: first world experience
    Ugo Boggi
    Division of General and Transplant Surgery, Pisa University Hospital, Pisa, Italy
    Transplantation 93:201-6. 2012
    ..The da Vinci surgical system, a computer-assisted electromechanical device, provides the unique opportunity to test whether laparoscopy can reduce the morbidity of pancreas transplantation...
  9. ncbi request reprint Outcome of 118 pancreas transplants with retroperitoneal portal-enteric drainage
    U Boggi
    Division of Surgery in Uremic and Diabetic Patients, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
    Transplant Proc 37:2648-50. 2005
    ..We have recently described a technique for retroperitoneal pancreas transplantation (RPTx) with portal-enteric drainage (PED). Further experience with 118 RPTx is detailed herein...
  10. ncbi request reprint Surveillance and rescue of pancreas grafts
    U Boggi
    Division of Surgery in Uremic and Diabetic Patients, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
    Transplant Proc 37:2644-7. 2005
    ..We herein report a single institution's experience with posttransplant surveillance and rescue of PA...
  11. ncbi request reprint Neoral versus prograf in simultaneous pancreas-kidney transplantation with portal venous drainage: three-year results of a single-center, open-label, prospective, randomized pilot study
    U Boggi
    Division of Surgery in Uremic and Diabetic Patients, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
    Transplant Proc 37:2641-3. 2005
    ....
  12. ncbi request reprint A technique for retroperitoneal pancreas transplantation with portal-enteric drainage
    Ugo Boggi
    Divisione di Chirurgia Generale e Trapianti, Universita di Pisa, Ospedale di Cisanello, Pisa, Italy
    Transplantation 79:1137-42. 2005
    ..We describe a new technique that circumvents these difficulties...
  13. ncbi request reprint Extracorporeal repair and liver autotransplantation after total avulsion of hepatic veins and retrohepatic inferior vena cava injury secondary to blunt abdominal trauma
    Ugo Boggi
    Divisione di Chirurgia Generale e Trapianti, Universita di Pisa, Pisa, Italy
    J Trauma 60:405-6. 2006
  14. ncbi request reprint Pancreas preservation with University of Wisconsin and Celsior solutions: a single-center, prospective, randomized pilot study
    Ugo Boggi
    Divisione di Chirurgia Generale e Trapianti, Dipartimento di Oncologia, Trapianti e Nuove Tecnologie in Medicina, Universita di Pisa, Pisa, Italy
    Transplantation 77:1186-90. 2004
    ..We report the results of a single-center, prospective, randomized pilot study specifically designed to compare the safety profile of Celsior solution with University of Wisconsin (UW) solution in clinical pancreas transplantation...
  15. ncbi request reprint Vascular complications of pancreatectomy
    Ugo Boggi
    Division of Surgery in Uremic and Diabetic Patient, University of Pisa Pisa, Italy
    JOP 8:102-13. 2007
    ....
  16. doi request reprint Robotic renal transplantation: first European case
    Ugo Boggi
    Divisione di Chirurgia Generale e Trapianti nell Uremico e nel Diabetico, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy
    Transpl Int 24:213-8. 2011
    ..Further experience is needed, but it is likely that solid organ transplantation will not remain immune to robotics...
  17. doi request reprint Contribution of contrast-enhanced ultrasonography to nonoperative management of segmental ischemia of the head of a pancreas graft
    U Boggi
    Divisione di Chirurgia Generale e Trapianti nell Uremico e nel Diabetico, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
    Am J Transplant 9:413-8. 2009
    ..To the best of our knowledge, this is the first description of the use of CEU in PTx and the first description of graft salvage, without partial pancreatectomy after CDU and CT diagnosis of segmental graft ischemia...
  18. doi request reprint Segmental live donor pancreas transplantation: review and critique of rationale, outcomes, and current recommendations
    Ugo Boggi
    Divisione di Chirurgia Generale e Trapianti nell Uremico e nel Diabetico, Università di Pisa e Azienda Ospedaliero Universitaria, Pisana, Pisa, Italy
    Clin Transplant 25:4-12. 2011
    ..Furthermore, LD allows recipient pre-conditioning and/or pair donor exchange. In conclusion, LD PTx may offer significant advantages to well-selected diabetic recipients. LDs are exposed to relatively small risks...
  19. pmc Current perspectives on laparoscopic robot-assisted pancreas and pancreas-kidney transplantation
    Ugo Boggi
    Division of General and Transplant Surgery, Pisa University Hospital, Via Paradisa 2, 56124 Pisa, Italy
    Rev Diabet Stud 8:28-34. 2011
    ..There is no proof that progressive graft warming produces actual damage to transplanted organs, unless exceedingly long. However, this important question is likely to elicit a vibrant discussion in the transplant community...
  20. doi request reprint Total duodenectomy with enteric duct drainage: a rescue operation for duodenal complications occurring after pancreas transplantation
    U Boggi
    Divisione di Chirurgia Generale e Trapianti nell Uremico e nel Diabetico, Ospedaliera Universitaria Pisana, Pisa, Italy
    Am J Transplant 10:692-7. 2010
    ..The two cases presented herein show that when DGC jeopardize pancreas function or recipient safety, total duodenectomy with enteric duct drainage may become an option...
  21. doi request reprint Prognostic implications of tumor invasion or adhesion to peripancreatic vessels in resected pancreatic cancer
    Ugo Boggi
    Divisione di Chirurgia Generale e Trapianti nell Uremico e nel Diabetico, Pisa, Italy
    Surgery 146:869-81. 2009
    ..The purpose of this study was to evaluate the operative risk and the prognostic implications of pancreatectomy plus resection and reconstruction of peripancreatic vessels (PPV) in patients with pancreatic adenocarcinoma...
  22. doi request reprint Robotic suture of a large caval injury caused by endo-GIA stapler malfunction during laparoscopic wedge resection of liver segments VII and VIII en-bloc with the right hepatic vein
    Ugo Boggi
    U O di Chirurgia Generale e Trapianti nell Uremico e nel Diabetico, Azienda Ospedaliera, Universitaria Pisana, Ospedale di Cisanello, Via Paradisa 2, 56124 Pisa, Italy
    Minim Invasive Ther Allied Technol 18:306-10. 2009
    ....
  23. ncbi request reprint Pancreas preservation with University of Wisconsin and Celsior solutions
    U Boggi
    Divisione di Chirurgia Generale e Trapianti, Universita di Pisa, Pisa, Italy
    Transplant Proc 36:563-5. 2004
    ..Although the use of Celsior has been recently described for heart, lung, liver, and kidney transplantation, no data are available on its use for clinical pancreas preservation...
  24. ncbi request reprint University of Wisconsin solution versus Celsior solution in clinical pancreas transplantation
    U Boggi
    Centro Regionale di Riferimento per la Cura delle Malattie del Pancreas, University of Pisa, Pisa, Italy
    Transplant Proc 37:1262-4. 2005
    ..This study compared the safety and efficacy of University of Wisconsin solution (UW) and Celsior solution (C) in pancreas transplantation (PTx)...
  25. ncbi request reprint Pancreas transplants from donors aged 45 years or older
    U Boggi
    Centro Regionale di Riferimento per La Cura delle Molattie del Pancreas, University of Pisa, Pisa, Italy
    Transplant Proc 37:1265-7. 2005
    ..Since donor age of 45 years or more is considered a relative contraindication for pancreas transplantation (PTx), we herein report our experience with these donors...
  26. ncbi request reprint Ninety-five percent insulin independence rate 3 years after pancreas transplantation alone with portal-enteric drainage
    U Boggi
    Department of Surgery and Transplantation, University of Pisa, Pisa, Italy
    Transplant Proc 37:1274-7. 2005
    ..We describe our experience with a consecutive series of 40 PTAs with PED...
  27. ncbi request reprint Pancreas transplantation from marginal donors
    U Boggi
    Divisione di Chirurgia Generale e Trapianti, Universita di Pisa, Pisa, Italy
    Transplant Proc 36:566-8. 2004
    ..Marginal donor organs are a supplementary source of grafts that has not been fully exploited for pancreas transplantation (PTx)...
  28. ncbi request reprint Simultaneous cadaver pancreas-living donor kidney transplantation
    U Boggi
    Divisione di Chirurgia Generale e Trapianti, Universita di Pisa, Pisa, Italy
    Transplant Proc 36:577-9. 2004
    ..Simultaneous cadaver pancreas-living kidney transplantation (SPLKTx) merges the advantages of LKD with those of cadaver donation, and may be an attractive alternative to simultaneous pancreas kidney transplantation (SPKTx)...
  29. ncbi request reprint Single-center, open, prospective, randomized pilot study comparing cyclosporine versus tacrolimus in simultaneous pancreas-kidney transplantation
    U Boggi
    Tuscany Region Referral Center for Treatment of Pancreatic Diseases, Pisa, Italy
    Transplant Proc 36:1064-6. 2004
    ....
  30. ncbi request reprint Retroperitoneal pancreas transplantation with portal-enteric drainage
    U Boggi
    Divisione di Chirurgia Generale e Trapianti, Universita di Pisa, Pisa, Italy
    Transplant Proc 36:571-4. 2004
    ..We herein describe the results of a modified technique for PED that places the pancreas in a totally retroperitoneal position...
  31. ncbi request reprint Solitary pancreas transplantation: preliminary findings about early reduction of proteinuria in incipient or evident diabetic type I nephropathy
    G Paleologo
    U O Nephrology with Transplants, A O P, Pisa, Italy
    Transplant Proc 36:591-6. 2004
    ..Our work was aimed to evaluate the precocious reduction of proteinuria in patients suffering from diabetes mellitus type 1 with incipient and evident nephropathy after isolated pancreas transplantation (PTA)...
  32. ncbi request reprint Kidney and pancreas transplants in Jehovah's witnesses: ethical and practical implications
    U Boggi
    Divisione di Chirurgia Generale e Trapianti, Dipartimento di Oncologia, Trapianti e Nuove Tecnologie in Medicina, Pisa, Italy
    Transplant Proc 36:601-2. 2004
    ..However, lifesaving transfusions may be needed later on, which raises additional and unique medical and ethical issues...
  33. ncbi request reprint Successful solitary pancreas transplantation with portal-enteric drainage following unsuccessful islet cell transplantation
    U Boggi
    University of Pisa, Pisa, Italy
    Transplant Proc 37:1278-9. 2005
    ..We herein describe the outcome of three SPTs with PVD performed after failed ITx...
  34. ncbi request reprint Simultaneous pancreas-kidney transplantation is improved by living kidney donation program
    U Boggi
    Tuscany Region Referral Center for Treatment of Pancreatic Diseases, Pisa, Italy
    Transplant Proc 36:1061-3. 2004
    ....
  35. ncbi request reprint Kidney transplantation from donors aged more than 65 years
    F Vistoli
    Divisione di Chirurgia Generale e Trapianti, Universita di Pisa, Pisa, Italy
    Transplant Proc 36:481-4. 2004
    ..There are no agreed criteria to predict the outcome of elderly donor kidneys or to decide between single (SKG) or dual (DKG) kidney graft transplantation...
  36. doi request reprint Effects of exposure of human islet beta-cells to normal and high glucose levels with or without gliclazide or glibenclamide
    S Del Guerra
    Department of Endocrinology and Metabolism, University of Pisa, Ospedale Cisanello, Italy
    Diabetes Metab 35:293-8. 2009
    ..To evaluate the effects of exposure to high glucose (HG) levels and sulphonylurea on isolated human islet-cell function, and to investigate some of the mechanisms that might be involved...
  37. doi request reprint Functional and survival analysis of isolated human islets
    V D'Aleo
    Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
    Transplant Proc 42:2250-1. 2010
    ..Pancreatic islet transplantation has become one of the potential treatments for type 1 diabetes. We evaluated functional and viability parameters of isolated islets in relation to donors clinical characteristics and preparation variables...
  38. ncbi request reprint Kidney transplantation from donors aged 65 years or more as single or dual grafts
    U Boggi
    Department of Surgery and Transplantation, University of Pisa, Pisa, Italy
    Transplant Proc 37:577-80. 2005
    ..We report the experience of two Italian transplant centers with single (SKTx) and dual (DKTx) kidney transplantation from donors aged 65 years or more...
  39. doi request reprint A common polymorphism in the monocyte chemoattractant protein-1 (MCP-1) gene regulatory region influences MCP-1 expression and function of isolated human pancreatic islets
    S Del Guerra
    Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy
    Transplant Proc 42:2247-9. 2010
    ..The aim of this study was to evaluate the presence and role of MCP-1 in isolated human islets, including genotyping for a common polymorphism...
  40. ncbi request reprint Portal enteric-drained solitary pancreas transplantation without surveillance biopsy: is it safe?
    U Boggi
    Tuscany Region Referral Center for Treatment of Pancreatic Diseases, Pisa, Italy
    Transplant Proc 36:1090-2. 2004
    ..Most solitary pancreas transplants (SPTx) fail due to unrecognized rejection episodes. Consequently, SPTx are monitored by drainage into the bladder or by surveillance biopsies...
  41. ncbi request reprint Small-bowel obstruction due to Bezoar following pancreas transplantation with portal-enteric drainage: a case report
    U Boggi
    Divisione di Chirurgia Generale e Trapianti, Universita di Pisa, Pisa, Italy
    Transplant Proc 36:575-6. 2004
    ..Small-bowel obstruction, however, is exceedingly rare; it has not been associated with an enhanced risk of graft loss...
  42. ncbi request reprint An alternative and simple method to consistently prepare viable isolated human islets for clinical transplantation
    M Bugliani
    Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
    Transplant Proc 36:605-6. 2004
    ..Improved simplicity and consistency, together with adequate quality of the preparations, are the main features of this isolation method...
  43. ncbi request reprint Multirow CT in the follow-up of pancreas transplantation
    E Neri
    Division of Diagnostic and Interventional Radiology, University of Pisa, Pisa, Italy
    Transplant Proc 36:597-600. 2004
    ..The purpose of the present study was to investigate the role of multirow CT in the follow-up of these patients...
  44. doi request reprint Evidence for a role of frataxin in pancreatic islets isolated from multi-organ donors with and without type 2 diabetes mellitus
    S Del Guerra
    Department of Endocrinology and Metabolism, Section of Metabolic Diseases and Diabetes, Pisa University Hospital, Pisa, Italy
    Horm Metab Res 44:471-5. 2012
    ..In islets from T2DM patients FXN expression is reduced while oxidative stress is increased and insulin release in response to glucose impaired...
  45. ncbi request reprint Laparoscopic and hand-assisted laparoscopic live donor nephrectomy
    A Pietrabissa
    Regional Center of Tuscany for Minimally Invasive Surgery and Advanced Technology, University of Pisa, Pisa, Italy
    Semin Laparosc Surg 8:161-7. 2001
    ..The spread of the new technique in our country and in the rest of Europe is likely to raise the issue of training in laparoscopic surgery for transplant surgeons...
  46. doi request reprint G-protein-coupled receptor 40 (GPR40) expression and its regulation in human pancreatic islets: the role of type 2 diabetes and fatty acids
    S Del Guerra
    University of Pisa, Dip Endocrinologia e Metabolismo, Sezione Metabolismo, Ospedale Cisanello, Via Paradisa 2, 56124 Pisa Italy
    Nutr Metab Cardiovasc Dis 20:22-5. 2010
    ..Little information is available on the expression of GPR40 and its regulation in human islets (HI)...
  47. ncbi request reprint Pancreas transplant alone has beneficial effects on retinopathy in type 1 diabetic patients
    R Giannarelli
    Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
    Diabetologia 49:2977-82. 2006
    ..We prospectively studied the course of diabetic retinopathy in PTA recipients and in non-transplanted (non-PTA) type 1 diabetic patients...
  48. ncbi request reprint Pancreas transplant alone
    P Marchetti
    Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
    Transplant Proc 36:569-70. 2004
    ..It restores normoglycemia in the vast majority of patients and seems to have a positive impact on late diabetic complications...
  49. ncbi request reprint Perioperative anesthetic management for laparoscopic kidney donation
    G Biancofiore
    Postsurgical and Transplant ICU, Azienda Ospedaliera Pisana, Ospedale di Cisanello, Pisa, Italy
    Transplant Proc 36:464-6. 2004
    ..To report a single-center experience about the perioperative and anesthetic management of laparoscopic living kidney donation...
  50. ncbi request reprint The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients
    P Marchetti
    Department of Endocrinology and Metabolism, Metabolic Unit, Ospedale Cisanello, University of Pisa, Via Paradisa 2, 56100, Pisa, Italy
    Diabetologia 50:2486-94. 2007
    ..Since ER stress has been associated with beta cell dysfunction, we studied several features of beta cell ER in human type 2 diabetes...
  51. ncbi request reprint Regional procurement team for abdominal organs
    S Signori
    Divisione di Chirurgia Generale e Trapianti, Universita di Pisa, Pisa, Italy
    Transplant Proc 36:435-6. 2004
    ..The graft shortages make multiorgan procurements mandatory. We describe the results of a regional procurement team policy that has been employed over a 5-year period...
  52. ncbi request reprint Echocardiographic evaluation in type 1 diabetic patients on waiting list for isolated pancreas or kidney-pancreas transplantation
    L Rondinini
    Cardiac and Thoracic Department, Pisa, Italy
    Transplant Proc 36:457-9. 2004
    ....
  53. ncbi request reprint Laparoscopic living donor nephrectomy in Italy: a national profile
    A Pietrabissa
    Divisione di Chirurgia Generale e Trapianti, Universita di Pisa, Pisa, Italy
    Transplant Proc 36:460-3. 2004
    ..A survey was therefore conducted in May 2003 to establish current practice patterns and to describe the outcome of this procedure...
  54. ncbi request reprint Cardiac evaluation for simultaneous pancreas-kidney transplantation and incidence of cardiac perioperative complications: preliminary study
    N Fossati
    I U O Anestesia e Rianimazione, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
    Transplant Proc 36:582-5. 2004
    ..A larger sample size is needed to give the study statistical power. Medium- and long-term follow-up studies are warranted to evaluate the effects of preoperative selection on survival rates...
  55. ncbi request reprint Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose
    S Del Guerra
    Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
    Diabetes Metab Res Rev 23:234-8. 2007
    ..Chronic exposure to high glucose levels is a probable underlying mechanism, whereas the role of oral anti-diabetic agents (sulphonylureas in particular) is still unsettled...
  56. ncbi request reprint Dissociation between carotid artery lesions and lipid parameters in recipients of successful kidney graft
    R Giannarelli
    Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy
    Diabetes Nutr Metab 16:232-5. 2003
    ..The relationships between lipid levels and atherosclerotic lesions of carotid arteries in kidney graft recipients are still unclear...
  57. doi request reprint Direct effects of rapid-acting insulin analogues on insulin signaling in human pancreatic islets in vitro
    V D'Aleo
    Department of Endocrinology and Metabolism, Ospedale Cisanello, Via Paradisa 2, University of Pisa, 56121 Pisa, Italy
    Diabetes Metab 37:324-9. 2011
    ..For this reason, the effects of insulin glulisine, insulin aspart and regular human insulin (RHI) on the function and molecular features of isolated human pancreatic islets were investigated...
  58. ncbi request reprint Rescue of kidney and pancreas grafts with complex vascular lesions
    U Boggi
    Divisione di Chirurgia Generale e Trapianti Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
    Transplant Proc 36:505-8. 2004
    ..The organ shortage mandates that grafts with complex vascular lesions be considered for graft rescue...
  59. doi request reprint Autophagy in human type 2 diabetes pancreatic beta cells
    M Masini
    Department of Experimental Pathology, University of Pisa, Pisa, Italy
    Diabetologia 52:1083-6. 2009
    ..We studied several features of autophagy in beta cells from type 2 diabetic patients and assessed the role of metabolic perturbation and pharmacological intervention...
  60. doi request reprint Adjuvant chemotherapy seems beneficial for invasive intraductal papillary mucinous neoplasms
    S Caponi
    Department of Oncology, Transplants, and New Technologies, U O Oncologia 2 Universitaria, Azienda Ospedaliero Universitaria Pisana, Polo Oncologico Area Vasta Nord Ovest, Istituto Toscano Tumori, Via Roma 67, 56126 Pisa, Italy
    Eur J Surg Oncol 39:396-403. 2013
    ..The objective of our study was to identify potential prognostic factors and to investigate the role of adjuvant therapies for patients radically resected for invasive IPMN...
  61. doi request reprint A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets
    P Marchetti
    Department of Endocrinology and Metabolism, University of Pisa, Via Paradisa 2, Pisa, Italy
    Diabetologia 55:3262-72. 2012
    ..We performed comprehensive morphological, functional and molecular studies to evaluate the presence and various features of a local GLP-1 system in human pancreatic islet cells, including those from type 2 diabetic patients...
  62. ncbi request reprint Bcl-2 expression in pancreas development and pancreatic cancer progression
    D Campani
    Department of Oncology, Division of Pathology, University of Pisa, Via Roma 57, 56126 Pisa, Italy
    J Pathol 194:444-50. 2001
    ....
  63. pmc Role of color Doppler sonography in post-transplant surveillance of vascular complications involving pancreatic allografts()
    L Morelli
    General and Transplantation Surgery, University of Pisa, Cisanello Hospital, Pisa, Italy
    J Ultrasound 11:18-21. 2008
    ..To evaluate the role of color Doppler ultrasonography in the postoperative surveillance of the vascular complications involving pancreas allografts...
  64. ncbi request reprint Insulin secretion defects of human type 2 diabetic islets are corrected in vitro by a new reactive oxygen species scavenger
    R Lupi
    Dipartimento di Endocrinologia e Metabolismo, University of Pisa, Italy
    Diabetes Metab 33:340-5. 2007
    ....
  65. ncbi request reprint Th2 cytokines have a partial, direct protective effect on the function and survival of isolated human islets exposed to combined proinflammatory and Th1 cytokines
    L Marselli
    Dipartimento di Endocrinologia e Metabolismo, Sezione Metabolismo, , Via Paradisa 2, 56100 Pisa, Italy
    J Clin Endocrinol Metab 86:4974-8. 2001
    ..These results suggest that Th2 and (at lower extent) Th3 cytokines may have a partial, direct protective effect on isolated human islets exposed to the cytostatic and cytotoxic action of proinflammatory and Th1 cytokines...
  66. doi request reprint The direct effects of GLP-1 and GIP, alone or in combination, on human pancreatic islets
    R Lupi
    Department of Endocrinology and Metabolism, University of Pisa, Cisanello Hospital, Via Paradisa 2, Pisa, Italy
    Regul Pept 165:129-32. 2010
    ....
  67. doi request reprint Secretin-stimulated multi-detector CT versus mangafodipir trisodium-enhanced MR imaging plus MRCP in characterization of non-metastatic solid pancreatic lesions
    P Boraschi
    2nd Department of Radiology, Pisa University Hospital, Via Paradisa 2, 56124 Pisa, Italy
    Dig Liver Dis 41:829-37. 2009
    ....
  68. ncbi request reprint Thoracoscopic splanchnicectomy for pain relief in unresectable pancreatic cancer
    A Pietrabissa
    Dipartimento di Oncologia, Universita di Pisa, Italy
    Arch Surg 135:332-5. 2000
    ..Unilateral truncal thoracoscopic splanchnicectomy (TS) provides safe and effective treatment for pain relief in patients with unresectable pancreatic cancer...
  69. ncbi request reprint Percutaneous cholecystostomy for acute cholecystitis in critically ill patients
    U Boggi
    Dipartimento di Oncologia, Universita di Pisa, Italy
    Hepatogastroenterology 46:121-5. 1999
    ..The aim of this study was to ascertain the therapeutic efficacy of percutaneous cholecystostomy in a selected group of high-risk patients who were physiologically unable to tolerate an open procedure...
  70. ncbi request reprint Nonoperative management of pancreatic pseudocysts. Problems in differential diagnosis
    U Boggi
    Dipartimento di Oncologia, Universita di Pisa, Italy
    Int J Pancreatol 25:123-33. 1999
    ..If all these precautions are adopted, pancreatic pseudocysts can be safely treated nonoperatively...
  71. ncbi request reprint Genetics of drug response to immunosuppressive treatment and prospects for personalized therapy
    R Danesi
    Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, 55 Via Roma, 56126 Pisa, Italy
    Mol Med Today 6:475-82. 2000
    ....
  72. ncbi request reprint Early morbidity after pancreas transplantation
    Maria Lucia Bindi
    U O Anestesia e Rianimazione 1, Unità di Terapia Intensiva Postchirurgica e Trapianti, Azienda Ospedaliera Universitaria Pisana, Ospedale Cisanello, Pisa, Italy
    Transpl Int 18:1356-60. 2005
    ..However, establishing the correct timing of PTA is of paramount importance in order not to expose the patients early to risks arising from a major surgery and heavy immunosuppressive treatments...
  73. ncbi request reprint Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion
    R Lupi
    Department of Endocrinology and Metabolism, Section of Diabetes, Ospedale Cisanello, Via Paradisa 2, 56100 Pisa, Italy
    Am J Physiol Endocrinol Metab 286:E560-7. 2004
    ....
  74. ncbi request reprint Untractable diarrhea due to late onset celiac disease of the adult following pancreatoduodenectomy
    U Boggi
    Division of General Surgery and Transplants, Department of Oncology, Transplants and New Technologies in Medicine, University of Pisa, 56124 Pisa, Italy
    Hepatogastroenterology 48:1030-2. 2001
    ..Recognition of the underlying occult celiac disease and institution of the appropriate dietary regimen allowed quick and expeditious recovery...
  75. ncbi request reprint [Orthotopic liver transplant. Analysis of costs related to anesthesiologic and intensive care phases]
    G Biancofiore
    Azienda Ospedaliera Pisana, Policlinico di Cisanello, Pisa
    Minerva Anestesiol 64:587-91. 1998
    ..To evaluate anesthesia and Intensive Care Unit (ICU) costs for Orthotopic Liver Transplantation (OLT) through a point by point analysis of the entire process from anesthesia induction to ICU discharge...
  76. doi request reprint The beta-cell in human type 2 diabetes
    Piero Marchetti
    Department of Endocrinology and Metabolism, Cisanello Hospital, 56124 Pisa, Italy
    Adv Exp Med Biol 654:501-14. 2010
    ..Encouraging, although preliminary, data show that some of these defects might be directly counteracted, at least in part, by appropriate in vitro pharmacological intervention...
  77. ncbi request reprint Functional and molecular defects of pancreatic islets in human type 2 diabetes
    Silvia Del Guerra
    Department of Endocrinology and Metabolism, Metabolic Unit, Ospedale Cisanello, Via Paradisa 2, 56124 Pisa, Italy
    Diabetes 54:727-35. 2005
    ..In this regard, it is suggested that reducing islet cell oxidative stress is a potential target of human type 2 diabetes therapy...
  78. ncbi request reprint Laparoscopic distal pancreatomy: are we ready for a standardized technique?
    Andrea Pietrabissa
    Divisione di Chirurgia Generale e Trapianti, Dipartimento di Oncologia, dei Trapianti e delle Nuove Tecnologie in Medicina Università di Pisa, Pisa, Italy
    Semin Laparosc Surg 11:179-83. 2004
    ..Finally, the hand-assisted approach can provide distinctive advantages over the pure laparoscopic technique in selected circumstances...
  79. ncbi request reprint Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin
    Piero Marchetti
    Department of Endocrinology and Metabolism and Diabetes, Transplant Unit, University of Pisa, Italy
    J Clin Endocrinol Metab 89:5535-41. 2004
    ..Thus, T2D islets have several functional and survival defects, which can be ameliorated by metformin; the beneficial effects of the drug are mediated, at least in part, by a reduction of oxidative stress...
  80. doi request reprint Multidetector CT in the evaluation of retroperitoneal fat tissue infiltration in ductal adenocarcinoma of the pancreatic head: correlation with histopathological findings
    Salvatore Mazzeo
    Division of Diagnostic and Interventional Radiology, University of Pisa, Via Roma, 67, Pisa, PI 56123, Italy
    Abdom Imaging 35:465-70. 2010
    ..Neoplastic infiltration of the retroportal fat tissue is a critical parameter in tumor staging and in surgical planning because it frequently represents a site of persistence and recurrence of disease...
  81. ncbi request reprint Insulin secretory function is impaired in isolated human islets carrying the Gly(972)-->Arg IRS-1 polymorphism
    Piero Marchetti
    Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
    Diabetes 51:1419-24. 2002
    ..These alterations may account for the increased predisposition to type 2 diabetes in individuals carrying the Gly(972)-->Arg amino acid polymorphism of IRS-1...
  82. ncbi request reprint Pancreatic transplants: secretin-stimulated MR pancreatography
    Piero Boraschi
    2nd Department of Radiology, Pisa University Hospital, Via Paradisa 2, 56124 Pisa, Italy
    Abdom Imaging 32:207-14. 2007
    ..Our study was aimed to evaluate the functional status of pancreatic transplants using dynamic MR pancreatography after secretin stimulation...
  83. ncbi request reprint A benefit-risk assessment of basiliximab in renal transplantation
    Ugo Boggi
    Division of General Surgery and Transplants, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
    Drug Saf 27:91-106. 2004
    ....
  84. doi request reprint The non-peptidyl low molecular weight radical scavenger IAC protects human pancreatic islets from lipotoxicity
    Valentina D'Aleo
    Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Italy
    Mol Cell Endocrinol 309:63-6. 2009
    ..0 mmol/l FFA on the function, survival and mRNA expression of several enzymes involved in the generation and scavenging of reactive oxygen species (ROS)...
  85. ncbi request reprint Is tacrolimus associated with fewer surgical complications than ciclosporin after kidney-pancreas transplantation?
    Ugo Boggi
    Divisione di Chirurgia nell Uremico e nel Diabetico Chirurgia Generale e Trapiantologica Università di Pisa Ospedale di Cisanello, Via Paradisa 2, 56124, Pisa, Italy
    Nat Clin Pract Nephrol 1:76-7. 2005
  86. ncbi request reprint Cystectomy and orthotopic ileal neobladder in a male patient 12 years after kidney transplantation; good preservation of the renal function
    Cesare Selli
    Urologia Universitaria, Dipartmento di Chirurgia, Via Roma 67, 56126 Pisa, Italy
    Transpl Int 17:97-100. 2004
    ..We conclude that the orthotopic ileal neobladder is an effective form of urinary diversion in renal transplant patients requiring cystectomy, allowing good preservation of the renal function...
  87. ncbi request reprint Efficacy and safety of basiliximab in kidney transplantation
    Ugo Boggi
    Division of Surgery in Uremic and Diabetic Patients General and Transplant Surgery, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
    Expert Opin Drug Saf 4:473-90. 2005
    ..However, life-threatening reactions were reported following re-exposure to basiliximab in recipients who lost graft function early after transplantation and, therefore, discontinued all immunosuppressive agents...
  88. ncbi request reprint Mangafodipir trisodium-enhanced MR imaging of pancreatic disease
    Piero Boraschi
    Second Department of Radiology, Pisa University Hospital, Via Paradisa 2, I 56124, Pisa, Italy
    Eur Radiol 16:988-97. 2006
    ..Mn-DPDP-enhanced MRI is an effective diagnostic tool for evaluating pancreatic disease...
  89. ncbi request reprint Hand-assisted laparoscopic low anterior resection: initial experience with a new procedure
    A Pietrabissa
    Divisione di Chirurgia Generale e Trapianti, Dipartimento di Oncologia, del Trapianti e delle Nuove Tecnologie in Medicina, Ospedale di Cisanello, via Paradisa 2 56124 Pisa, Italy
    Surg Endosc 16:431-5. 2002
    ..In the treatment of rectal cancer, HALS could reproduce an operative setting similar to that of the open approach...
  90. ncbi request reprint Perioperative management for laparoscopic kidney donation
    G Biancofiore
    Postsurgical and Transplant ICU, Department of Anaesthesia and Intensive Care Cisanello Hospital, Pisa, Italy
    Minerva Anestesiol 69:681-6, 686-9. 2003
    ..To report a single centre's experience in the perioperative management of live kidney laparoscopic donations. METHODS...
  91. ncbi request reprint Pancreas transplant alone determines early improvement of cardiovascular risk factors and cardiac function in type 1 diabetic patients
    Alberto Coppelli
    Department of Endocrinology and Metabolism, Metabolic Unit, Cisanello Hospital Pisa University, Pisa, Italy
    Transplantation 76:974-6. 2003
    ..The effects of pancreas transplant alone (PTA) on cardiovascular risk factors (CRF) and cardiac function in type 1 diabetes mellitus (T1DM) patients are still unsettled...
  92. ncbi request reprint The direct effects of the angiotensin-converting enzyme inhibitors, zofenoprilat and enalaprilat, on isolated human pancreatic islets
    Roberto Lupi
    Metabolic Unit, Department of Endocrinology and Metabolism, University of Pisa, Ospedale Cisanello, Via Paradisa 2, 56100 Pisa, Italy
    Eur J Endocrinol 154:355-61. 2006
    ....
  93. ncbi request reprint Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated
    Roberto Lupi
    Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy
    Diabetes 51:1437-42. 2002
    ..The cytostatic action is likely to be due to the FFA-induced reduction of intraislet glucose metabolism, and the proapoptotic effects are mostly caspase mediated, partially dependent on ceramide pathway, and possibly Bcl-2 regulated...
  94. ncbi request reprint Lipotoxicity in human pancreatic islets and the protective effect of metformin
    Roberto Lupi
    Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
    Diabetes 51:S134-7. 2002
    ..Metformin prevents these deleterious effects, supporting a direct protective action on human beta-cells...
  95. ncbi request reprint The role of peripheral benzodiazepine receptors on the function and survival of isolated human pancreatic islets
    Lorella Marselli
    Dipartimento di Endocrinologia e Metabolismo, Sezione Metabolismo, Universita di Pisa, Via Paradisa 2, Ospedale Cisanello, 56100 Pisa, Italy
    Eur J Endocrinol 151:207-14. 2004
    ..We hypothesized that PBRs can have a role in human islet physiopathology, and evaluated the effects of prolonged exposure to two specific PBR ligands, PK11195 and Ro5-4864 on the function and survival of isolated human islets...
  96. ncbi request reprint Improved insulin secretory function and reduced chemotactic properties after tissue culture of islets from type 1 diabetic patients
    Roberto Lupi
    Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
    Diabetes Metab Res Rev 20:246-51. 2004
    ..Type 1 diabetes results from the destruction of pancreatic beta-cell as a consequence of an autoimmune process. To date, information on the properties of islets isolated from type 1 diabetic patients is very scant...
  97. ncbi request reprint Percutaneous nephrolithotomy of transplanted kidney
    Francesco Francesca
    Division of Urology, S Chiara Hospital, Pisa, Italy
    J Endourol 16:225-7. 2002
    ..The technical aspects of the procedure, such as patient position and the use of the ultrasound-guided caliceal puncture, are stressed...
  98. ncbi request reprint A simplified technique for the en bloc procurement of abdominal organs that is suitable for pancreas and small-bowel transplantation
    Ugo Boggi
    Divisione di Chirurgia Generale e Trapianti, Dipartimento di Oncologia, Trapianti e Nuove Tecnologie in Medicina, Universita di Pisa, and U O Nefrologia e Trapianti, Azienda Ospedaliera Pisana, Italy
    Surgery 135:629-41. 2004
    ..We describe the results of a simplified method for the en bloc procurement of multiple organs, which permits isolated transplantation of all abdominal grafts, including the pancreas and the small bowel, to different recipients...
  99. ncbi request reprint Beneficial effect of the nonpeptidyl low molecular weight radical scavenger IAC on cultured human islet function
    Rita Mancarella
    Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
    Cell Transplant 17:1271-6. 2008
    ..We found that IAC markedly reduced oxidative stress and ameliorated islets function. These results suggest that the use of IAC could be an interesting pharmacological approach for the treatment of the islets before transplantation...
  100. ncbi request reprint Early improvement of unstable diabetic retinopathy after solitary pancreas transplantation
    Rosa Giannarelli
    Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Italy
    Diabetes Care 25:2358-9. 2002
  101. ncbi request reprint Cancer risk among the relatives of patients with pancreatic ductal adenocarcinoma
    Marco Del Chiaro
    Regional Referral Center for Pancreatic Diseases Treatment, University of Pisa, Pisa, Italy
    Pancreatology 7:459-69. 2007
    ..Our aims were to examine familial aggregations of pancreas and other cancers, and to determine the relative risk of the family members...