Research Topics
| U BoggiSummaryAffiliation: University of Pisa Country: Italy Publications
| Collaborators
|
Detail Information
Publications
Results of pancreas transplantation alone with special attention to native kidney function and proteinuria in type 1 diabetes patientsUgo Boggi
Division of General and Transplant Surgery in Uremic and Diabetic Patients, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
Rev Diabet Stud 8:259-67. 2011..Further improvements were recorded in several cardiovascular risk factors, retinopathy, and neuropathy. We conclude that PTA was an effective and reasonably safe procedure in this single-center experience...
Percutaneous cholecystostomy for acute cholecystitis in critically ill patientsU Boggi
Dipartimento di Oncologia, Universita di Pisa, Italy
Hepatogastroenterology 46:121-5. 1999..The aim of this study was to ascertain the therapeutic efficacy of percutaneous cholecystostomy in a selected group of high-risk patients who were physiologically unable to tolerate an open procedure...
University of Wisconsin solution versus Celsior solution in clinical pancreas transplantationU Boggi
Centro Regionale di Riferimento per la Cura delle Malattie del Pancreas, University of Pisa, Pisa, Italy
Transplant Proc 37:1262-4. 2005..3% and 75.0% for UW compared with 90.4% and 90.4% for C (P = NS). CONCLUSIONS: Within the range of cold ischemia times reported in this study, UW and C show similar safety and efficacy profiles for PTx...
Pancreas transplants from donors aged 45 years or olderU Boggi
Centro Regionale di Riferimento per La Cura delle Molattie del Pancreas, University of Pisa, Pisa, Italy
Transplant Proc 37:1265-7. 2005..2% and 67.7%, respectively. CONCLUSIONS: Meticulous donor selection and short preservation times allow the safe use of pancreases procured from donors aged 45 years or older, thus expanding the donor pool for PTx procedures...
Solitary pancreas transplantation: preliminary findings about early reduction of proteinuria in incipient or evident diabetic type I nephropathyG Paleologo
U.O. Nephrology with Transplants, A.O.P, Pisa, Italy
Transplant Proc 36:591-6. 2004..CONCLUSIONS: TPA seems to reduce, and in some cases to regress, the proteinuria associated with early diabetic nephropathy...
Pancreas transplantation from marginal donorsU Boggi
Divisione di Chirurgia Generale e Trapianti, , Pisa, Italy
Transplant Proc 36:566-8. 2004..7% and 94.2% for NMD and MD, respectively (P >.05). Equivalent figures for patients were 97.9% and 98.1%, respectively (P >.05). CONCLUSIONS: Pancreas from MD may be safely employed and significantly expand the donor pool for PTx...
Outcome of 118 pancreas transplants with retroperitoneal portal-enteric drainageU Boggi
Division of Surgery in Uremic and Diabetic Patients, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
Transplant Proc 37:2648-50. 2005..We have recently described a technique for retroperitoneal pancreas transplantation (RPTx) with portal-enteric drainage (PED). Further experience with 118 RPTx is detailed herein...
Ninety-five percent insulin independence rate 3 years after pancreas transplantation alone with portal-enteric drainageU Boggi
Department of Surgery and Transplantation, University of Pisa, Pisa, Italy
Transplant Proc 37:1274-7. 2005..CONCLUSIONS: Pancreas transplantation alone with PED provides high rates of long-term insulin-independence...
Kidney and pancreas transplants in Jehovah's witnesses: ethical and practical implicationsU Boggi
Divisione di Chirurgia Generale e Trapianti, Dipartimento di Oncologia, Trapianti e Nuove Tecnologie in Medicina, Pisa, Italy
Transplant Proc 36:601-2. 2004..However, lifesaving transfusions may be needed later on, which raises additional and unique medical and ethical issues...
Neoral versus prograf in simultaneous pancreas-kidney transplantation with portal venous drainage: three-year results of a single-center, open-label, prospective, randomized pilot studyU Boggi
Division of Surgery in Uremic and Diabetic Patients, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
Transplant Proc 37:2641-3. 2005....
Single-center, open, prospective, randomized pilot study comparing cyclosporine versus tacrolimus in simultaneous pancreas-kidney transplantationU Boggi
Tuscany Region Referral Center for Treatment of Pancreatic Diseases, Pisa, Italy
Transplant Proc 36:1064-6. 2004..CONCLUSIONS: Although a larger series and a longer follow-up are needed, Neoral and Prograf used in combination with MMF seem to achieve equivalent success rates among primary SPKTx when the pancreas is drained into the portal vein...
Simultaneous cadaver pancreas-living donor kidney transplantationU Boggi
Divisione di Chirurgia Generale e Trapianti, , Pisa, Italy
Transplant Proc 36:577-9. 2004..0% and 84.0% for SPLKTx and 96.9% and 96.9% for SPKTx. CONCLUSIONS: SPLKTx is a valuable alternative to SPKTx. Further development of SPLKTX relies on increased rates of living kidney donation...
Surveillance and rescue of pancreas graftsU Boggi
Division of Surgery in Uremic and Diabetic Patients, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
Transplant Proc 37:2644-7. 2005..We herein report a single institution's experience with posttransplant surveillance and rescue of PA...
Simultaneous pancreas-kidney transplantation is improved by living kidney donation programU Boggi
Tuscany Region Referral Center for Treatment of Pancreatic Diseases, Pisa, Italy
Transplant Proc 36:1061-3. 2004..CONCLUSIONS: LKD expanded the kidney donor pool, reduced the waiting time of recipients listed for a totally cadaveric procedure, and increased their chance to get a timely graft. One-year outcome of SPLKTx equaled that of SPKTx...
Functional and survival analysis of isolated human isletsV D'Aleo
Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
Transplant Proc 42:2250-1. 2010..Pancreatic islet transplantation has become one of the potential treatments for type 1 diabetes. We evaluated functional and viability parameters of isolated islets in relation to donors clinical characteristics and preparation variables...
Kidney transplantation from donors aged 65 years or more as single or dual graftsU Boggi
Department of Surgery and Transplantation, University of Pisa, Pisa, Italy
Transplant Proc 37:577-80. 2005..CONCLUSION: Careful donor selection, short preservation time, and tailored immunosuppression allow safe and efficient use of elderly donor kidneys...
Retroperitoneal pancreas transplantation with portal-enteric drainageU Boggi
Divisione di Chirurgia Generale e Trapianti, , Pisa, Italy
Transplant Proc 36:571-4. 2004..Whether retroperitoneal graft placement has actual advantages over the "classical" intraperitoneal position remains to be ascertained...
Successful solitary pancreas transplantation with portal-enteric drainage following unsuccessful islet cell transplantationU Boggi
University of Pisa, Pisa, Italy
Transplant Proc 37:1278-9. 2005..Further experience is needed to define contraindications and possible complications of SPT with PVD following ITx...
Pancreas preservation with University of Wisconsin and Celsior solutionsU Boggi
Divisione di Chirurgia Generale e Trapianti, , Pisa, Italy
Transplant Proc 36:563-5. 2004..0% for UW as compared with 96.4% for Celsior (P = NS). CONCLUSIONS: Within the range of cold ischemia times reported in this study, UW and Celsior solutions have similar safety profiles for pancreas transplantation...
A common polymorphism in the monocyte chemoattractant protein-1 (MCP-1) gene regulatory region influences MCP-1 expression and function of isolated human pancreatic isletsS Del Guerra
Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy
Transplant Proc 42:2247-9. 2010..The aim of this study was to evaluate the presence and role of MCP-1 in isolated human islets, including genotyping for a common polymorphism...
Evidence for a role of frataxin in pancreatic islets isolated from multi-organ donors with and without type 2 diabetes mellitusS Del Guerra
Department of Endocrinology and Metabolism, Section of Metabolic Diseases and Diabetes, Pisa University Hospital, Pisa, Italy
Horm Metab Res 44:471-5. 2012..In islets from T2DM patients FXN expression is reduced while oxidative stress is increased and insulin release in response to glucose impaired...
Portal enteric-drained solitary pancreas transplantation without surveillance biopsy: is it safe?U Boggi
Tuscany Region Referral Center for Treatment of Pancreatic Diseases, Pisa, Italy
Transplant Proc 36:1090-2. 2004..Most solitary pancreas transplants (SPTx) fail due to unrecognized rejection episodes. Consequently, SPTx are monitored by drainage into the bladder or by surveillance biopsies...
Pancreas transplant alone has beneficial effects on retinopathy in type 1 diabetic patientsR Giannarelli
Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
Diabetologia 49:2977-82. 2006..CONCLUSIONS/INTERPRETATION: Despite a relatively short follow-up, our study shows that successful PTA can positively affect the course of diabetic retinopathy...
Total duodenectomy with enteric duct drainage: a rescue operation for duodenal complications occurring after pancreas transplantationU Boggi
Divisione di Chirurgia Generale e Trapianti nell Uremico e nel Diabetico, Ospedaliera Universitaria Pisana, Pisa, Italy
Am J Transplant 10:692-7. 2010..The two cases presented herein show that when DGC jeopardize pancreas function or recipient safety, total duodenectomy with enteric duct drainage may become an option...
Laparoscopic and hand-assisted laparoscopic live donor nephrectomyA Pietrabissa
Regional Center of Tuscany for Minimally Invasive Surgery and Advanced Technology, University of Pisa, Pisa, Italy
Semin Laparosc Surg 8:161-7. 2001..The spread of the new technique in our country and in the rest of Europe is likely to raise the issue of training in laparoscopic surgery for transplant surgeons...
An alternative and simple method to consistently prepare viable isolated human islets for clinical transplantationM Bugliani
Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
Transplant Proc 36:605-6. 2004..Improved simplicity and consistency, together with adequate quality of the preparations, are the main features of this isolation method...
Multirow CT in the follow-up of pancreas transplantationE Neri
Division of Diagnostic and Interventional Radiology, University of Pisa, Pisa, Italy
Transplant Proc 36:597-600. 2004..The purpose of the present study was to investigate the role of multirow CT in the follow-up of these patients...
Small-bowel obstruction due to Bezoar following pancreas transplantation with portal-enteric drainage: a case reportU Boggi
Divisione di Chirurgia Generale e Trapianti, , Pisa, Italy
Transplant Proc 36:575-6. 2004....
Perioperative anesthetic management for laparoscopic kidney donationG Biancofiore
Postsurgical and Transplant ICU, Azienda Ospedaliera Pisana, Ospedale di Cisanello, Pisa, Italy
Transplant Proc 36:464-6. 2004..To report a single-center experience about the perioperative and anesthetic management of laparoscopic living kidney donation...
Cardiac evaluation for simultaneous pancreas-kidney transplantation and incidence of cardiac perioperative complications: preliminary studyN Fossati
I U O Anestesia e Rianimazione, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
Transplant Proc 36:582-5. 2004..A larger sample size is needed to give the study statistical power. Medium- and long-term follow-up studies are warranted to evaluate the effects of preoperative selection on survival rates...
Laparoscopic living donor nephrectomy in Italy: a national profileA Pietrabissa
Divisione di Chirurgia Generale e Trapianti, Universita di Pisa, Pisa, Italy
Transplant Proc 36:460-3. 2004..A survey was therefore conducted in May 2003 to establish current practice patterns and to describe the outcome of this procedure...
The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patientsP Marchetti
Department of Endocrinology and Metabolism, Metabolic Unit, Ospedale Cisanello, University of Pisa, Via Paradisa 2, 56100, Pisa, Italy
Diabetologia 50:2486-94. 2007..Since ER stress has been associated with beta cell dysfunction, we studied several features of beta cell ER in human type 2 diabetes...
Contribution of contrast-enhanced ultrasonography to nonoperative management of segmental ischemia of the head of a pancreas graftU Boggi
Divisione di Chirurgia Generale e Trapianti nell Uremico e nel Diabetico, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
Am J Transplant 9:413-8. 2009..To the best of our knowledge, this is the first description of the use of CEU in PTx and the first description of graft salvage, without partial pancreatectomy after CDU and CT diagnosis of segmental graft ischemia...
Kidney transplantation from donors aged more than 65 yearsF Vistoli
Divisione di Chirurgia Generale e Trapianti, Universita di Pisa, Pisa, Italy
Transplant Proc 36:481-4. 2004..There are no agreed criteria to predict the outcome of elderly donor kidneys or to decide between single (SKG) or dual (DKG) kidney graft transplantation...
Pancreas transplant aloneP Marchetti
Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
Transplant Proc 36:569-70. 2004..It restores normoglycemia in the vast majority of patients and seems to have a positive impact on late diabetic complications...
Role of color Doppler sonography in post-transplant surveillance of vascular complications involving pancreatic allografts()L Morelli
General and Transplantation Surgery, University of Pisa, Cisanello Hospital, Pisa, Italy
J Ultrasound 11:18-21. 2008..To evaluate the role of color Doppler ultrasonography in the postoperative surveillance of the vascular complications involving pancreas allografts...
Autophagy in human type 2 diabetes pancreatic beta cellsM Masini
Department of Experimental Pathology, University of Pisa, Pisa, Italy
Diabetologia 52:1083-6. 2009..We studied several features of autophagy in beta cells from type 2 diabetic patients and assessed the role of metabolic perturbation and pharmacological intervention...
Rescue of kidney and pancreas grafts with complex vascular lesionsU Boggi
Divisione di Chirurgia Generale e Trapianti Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
Transplant Proc 36:505-8. 2004..1 years). CONCLUSIONS: Careful patient selection, multidisciplinary evaluation, and personalized surgical technique may allow the rescue of kidney and pancreas grafts with complex vascular lesions that, otherwise, would be lost...
Nonoperative management of pancreatic pseudocysts. Problems in differential diagnosisU Boggi
Dipartimento di Oncologia, Universita di Pisa, Italy
Int J Pancreatol 25:123-33. 1999..If all these precautions are adopted, pancreatic pseudocysts can be safely treated nonoperatively...
The direct effects of GLP-1 and GIP, alone or in combination, on human pancreatic isletsR Lupi
Department of Endocrinology and Metabolism, University of Pisa, Cisanello Hospital, Via Paradisa 2, Pisa, Italy
Regul Pept 165:129-32. 2010....
Echocardiographic evaluation in type 1 diabetic patients on waiting list for isolated pancreas or kidney-pancreas transplantationL Rondinini
Cardiac and Thoracic Department, Pisa, Italy
Transplant Proc 36:457-9. 2004....
Thoracoscopic splanchnicectomy for pain relief in unresectable pancreatic cancerA Pietrabissa
Dipartimento di Oncologia, Universita di Pisa, Italy
Arch Surg 135:332-5. 2000..Unilateral truncal thoracoscopic splanchnicectomy (TS) provides safe and effective treatment for pain relief in patients with unresectable pancreatic cancer...
A local glucagon-like peptide 1 (GLP-1) system in human pancreatic isletsP Marchetti
Department of Endocrinology and Metabolism, University of Pisa, Via Paradisa 2, 56126, Pisa, Italy
Diabetologia 55:3262-72. 2012..We performed comprehensive morphological, functional and molecular studies to evaluate the presence and various features of a local GLP-1 system in human pancreatic islet cells, including those from type 2 diabetic patients...
Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucoseS Del Guerra
Department of Endocrinology and Metabolism, Metabolic Unit, University of Pisa, Pisa, Italy
Diabetes Metab Res Rev 23:234-8. 2007..Chronic exposure to high glucose levels is a probable underlying mechanism, whereas the role of oral anti-diabetic agents (sulphonylureas in particular) is still unsettled...
Dissociation between carotid artery lesions and lipid parameters in recipients of successful kidney graftR Giannarelli
Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy
Diabetes Nutr Metab 16:232-5. 2003..The relationships between lipid levels and atherosclerotic lesions of carotid arteries in kidney graft recipients are still unclear...
Percutaneous nephrolithotomy of transplanted kidneyFrancesco Francesca
Division of Urology, S Chiara Hospital, Pisa, Italy
J Endourol 16:225-7. 2002..The technical aspects of the procedure, such as patient position and the use of the ultrasound-guided caliceal puncture, are stressed...
Immunosuppressive monoclonal antibodies: current and next generationD Focosi
U O Immuoematologia SSN, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy
Clin Microbiol Infect 17:1759-68. 2011..We review here the current and next generation of mAbs and the risks that infectious disease specialists should be aware of...
Regional procurement team for abdominal organsS Signori
Divisione di Chirurgia Generale e Trapianti, , Pisa, Italy
Transplant Proc 36:435-6. 2004....
Perioperative management for laparoscopic kidney donationG Biancofiore
Postsurgical and Transplant ICU, Department of Anaesthesia and Intensive Care Cisanello Hospital, Pisa, Italy
Minerva Anestesiol 69:681-6, 686-9. 2003..To report a single centre's experience in the perioperative management of live kidney laparoscopic donations. METHODS...
Hand-assisted laparoscopic low anterior resection: initial experience with a new procedureA Pietrabissa
Divisione di Chirurgia Generale e Trapianti, Dipartimento di Oncologia, del Trapianti e delle Nuove Tecnologie in Medicina, Ospedale di Cisanello, via Paradisa 2 56124 Pisa, Italy
Surg Endosc 16:431-5. 2002..In the treatment of rectal cancer, HALS could reproduce an operative setting similar to that of the open approach...
