Beatrice Bodega

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. ncbi The boundary of macaque rDNA is constituted by low-copy sequences conserved during evolution
    B Bodega
    Dipartimento di Biologia e Genetica per le Scienze Mediche, Universita di Milano, 20133 Milano, Italy
    Genomics 88:564-71. 2006
  2. pmc Remodeling of the chromatin structure of the facioscapulohumeral muscular dystrophy (FSHD) locus and upregulation of FSHD-related gene 1 (FRG1) expression during human myogenic differentiation
    Beatrice Bodega
    Department of Biology and Genetics for Medical Sciences, University of Milan, Milan, Italy
    BMC Biol 7:41. 2009
  3. pmc Evolutionary history of linked D4Z4 and Beta satellite clusters at the FSHD locus (4q35)
    Marta Giussani
    Department of Biology and Genetics for Medical Sciences, University of Milan, Milan, Italy
    Genomics 100:289-96. 2012
  4. pmc Expression profiling of FSHD-1 and FSHD-2 cells during myogenic differentiation evidences common and distinctive gene dysregulation patterns
    Stefania Cheli
    Department of Biology and Genetics for Medical Sciences, University of Milan, Milan, Italy
    PLoS ONE 6:e20966. 2011
  5. pmc Evolutionary genomic remodelling of the human 4q subtelomere (4q35.2)
    Beatrice Bodega
    Department of Biology and Genetics for Medical Sciences, University of Milan, Milan, Italy
    BMC Evol Biol 7:39. 2007
  6. pmc A long ncRNA links copy number variation to a polycomb/trithorax epigenetic switch in FSHD muscular dystrophy
    Daphne S Cabianca
    Dulbecco Telethon Institute at San Raffaele Scientific Institute, Division of Regenerative Medicine, Stem Cells, and Gene Therapy, Milan, Italy
    Cell 149:819-31. 2012

Collaborators

Detail Information

Publications6

  1. ncbi The boundary of macaque rDNA is constituted by low-copy sequences conserved during evolution
    B Bodega
    Dipartimento di Biologia e Genetica per le Scienze Mediche, Universita di Milano, 20133 Milano, Italy
    Genomics 88:564-71. 2006
    ..3 sequences were lacking. Thus, although evolutionary events modified the sequence organization of the MMU rDNA boundary, its overall sequence feature and the preferential location in vicinity to the NOR have been conserved...
  2. pmc Remodeling of the chromatin structure of the facioscapulohumeral muscular dystrophy (FSHD) locus and upregulation of FSHD-related gene 1 (FRG1) expression during human myogenic differentiation
    Beatrice Bodega
    Department of Biology and Genetics for Medical Sciences, University of Milan, Milan, Italy
    BMC Biol 7:41. 2009
    ..Furthermore, a mouse model overexpressing FRG1 has been generated, displaying skeletal muscle defects...
  3. pmc Evolutionary history of linked D4Z4 and Beta satellite clusters at the FSHD locus (4q35)
    Marta Giussani
    Department of Biology and Genetics for Medical Sciences, University of Milan, Milan, Italy
    Genomics 100:289-96. 2012
    ..In conclusion, this paper provides evidence that at the 4q subtelomere the linkage between D4Z4 and Beta satellite arrays is a feature that appeared late during evolution and is conserved between chimpanzee and humans...
  4. pmc Expression profiling of FSHD-1 and FSHD-2 cells during myogenic differentiation evidences common and distinctive gene dysregulation patterns
    Stefania Cheli
    Department of Biology and Genetics for Medical Sciences, University of Milan, Milan, Italy
    PLoS ONE 6:e20966. 2011
    ..Determine global gene dysregulation affecting 4q-linked (FSHD-1) and non 4q-linked (FSHD-2) cells during early stages of myogenic differentiation. This approach has been never applied to FSHD pathogenesis...
  5. pmc Evolutionary genomic remodelling of the human 4q subtelomere (4q35.2)
    Beatrice Bodega
    Department of Biology and Genetics for Medical Sciences, University of Milan, Milan, Italy
    BMC Evol Biol 7:39. 2007
    ..2 domain harbouring the facioscapulohumeral muscular dystrophy (FSHD) locus, we investigated in African apes genomic and chromatin organisations, and the nuclear topology of orthologous regions...
  6. pmc A long ncRNA links copy number variation to a polycomb/trithorax epigenetic switch in FSHD muscular dystrophy
    Daphne S Cabianca
    Dulbecco Telethon Institute at San Raffaele Scientific Institute, Division of Regenerative Medicine, Stem Cells, and Gene Therapy, Milan, Italy
    Cell 149:819-31. 2012
    ..This study provides insights into the biological function of repetitive sequences in regulating gene expression and shows how mutations of such elements can influence the progression of a human genetic disease...