Research Topics
Species | Francesco BoccardoSummaryAffiliation: University of Genoa Country: Italy Publications
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Detail Information
Publications
Dihydrotestosterone and bicalutamide do not affect Periostin expression in androgen-dependent LNCaP prostate cancer cell linesFrancesca Argellati
IRCCS San Martino University Hospital IST National Cancer Research Institute and the University of Genoa, Academic Unit of Medical Oncology UOC Oncologia Medica B, Largo Rosanna Benzi 10, 16132 Genoa, Italy
Anticancer Res 33:815-20. 2013..To investigate periostin (POSTN) expression in the LNCaP cell line...- Influence of bicalutamide with or without tamoxifen or anastrozole on insulin-like growth factor 1 and binding proteins in prostate cancer patientsF Boccardo
Department of Medical Oncology, National Cancer Research Institute and University of Genoa, Italy
Int J Biol Markers 21:123-6. 2006..There is growing evidence that IGF-1 and binding proteins may be involved in prostate cancer promotion and progression... - 4-OH tamoxifen does not interfere with bicalutamide inhibitory effects on human prostatic cancer cells in vitroF Boccardo
University of Genoa, Italy
Anticancer Res 25:4277-80. 2005..The present study was aimed at investigating the effects of the co-administration of 4-OH Tamoxifen (4HT) and bicalutamide (BIC) on the human prostate cancer cell line LNCaP in vitro... - Enterolactone as a risk factor for breast cancer: a review of the published evidenceFrancesco Boccardo
University of Genoa, Genoa, Italy
Clin Chim Acta 365:58-67. 2006..In summary, epidemiological evidence to date is conflicting. Prospective large scale studies will require assessing the consumption of antibiotics and dietary habits during adolescence in order to obtain definitive conclusions... - Switching to anastrozole versus continued tamoxifen treatment of early breast cancer: preliminary results of the Italian Tamoxifen Anastrozole TrialFrancesco Boccardo
National Cancer Research Institute, 16132 Genoa, Italy
J Clin Oncol 23:5138-47. 2005..Moreover, many women relapse during or after tamoxifen therapy because of the development of resistance. Therefore new approaches are required... - Switching to aromatase inhibitors in early breast cancerFrancesco Boccardo
Department of Medical Oncology, National Cancer Research Institute, Genoa, Italy
Lancet 369:533-5. 2007 - Switching to anastrozole versus continued tamoxifen treatment of early breast cancer. Updated results of the Italian tamoxifen anastrozole (ITA) trialF Boccardo
The National Cancer Research Institute and the University of Genoa, Genoa, Italy
Ann Oncol 17:vii10-4. 2006..Moreover, many women relapse during or after tamoxifen therapy due to the development of resistance. This provided the rationale for a switching trial with anastrozole, the updated results of which are reported here... 
Prednisone plus gefitinib versus prednisone plus placebo in the treatment of hormone-refractory prostate cancer: a randomized phase II trialFrancesco Boccardo
The National Cancer Research Institute and the University of Genoa, Genoa, Italy
Oncology 74:223-8. 2008..Abnormal epidermal growth factor receptor expression and pre-clinical data prompted us to investigate the activity of gefitinib, a selective epidermal growth factor receptor tyrosine kinase inhibitor, in hormone-refractory prostate cancer...- Evaluation of tamoxifen and anastrozole in the prevention of gynecomastia and breast pain induced by bicalutamide monotherapy of prostate cancerF Boccardo
University and National Cancer Research Institute, University of Genoa, Genoa, Italy
J Clin Oncol 23:808-15. 2005..To determine whether tamoxifen or anastrozole prevents gynecomastia and breast pain caused by bicalutamide (150 mg) without compromising efficacy, safety, or sexual functioning... - Adjuvant chemotherapy of bladder cancerF Boccardo
National Cancer Research Institute and University of Genoa, Genoa, Italy
Ann Oncol 17:v129-32. 2006..Optimal treatment for high risk patients includes local and perioperative systemic therapy (adjuvant or neoadjuvant chemotherapy)... - Switching to anastrozole after tamoxifen improves survival in postmenopausal women with breast cancerFrancesco Boccardo
Department of Oncology, Biology and Genetics, University of Genoa, Genoa, Italy
Nat Clin Pract Oncol 5:76-7. 2008 - Exploratory study of drug plasma levels during bicalutamide 150 mg therapy co-administered with tamoxifen or anastrozole for prophylaxis of gynecomastia and breast pain in men with prostate cancerFrancesco Boccardo
Professorial Unit of Medical Oncology, University and National Cancer Research Institute, Largo R Benzi 10, 16132, Genoa, Italy
Cancer Chemother Pharmacol 56:415-20. 2005.... - Prognostic value of nuclear matrix protein expression in localized prostate cancerFrancesco Ricci
Department of Internal Medicine, School of Medicine, University of Genoa, Genoa, Italy
J Cancer Res Clin Oncol 138:1379-84. 2012..The aim of the study was to correlate nuclear matrix (NM) protein expression profiles with the risk of PSA progression or death in early prostate cancer (PCa)... - An open, randomised, multicentre, phase 3 trial comparing the efficacy of two tamoxifen schedules in preventing gynaecomastia induced by bicalutamide monotherapy in prostate cancer patientsDavide Bedognetti
University of Genoa, Genoa, Italy
Eur Urol 57:238-45. 2010..To reduce the exposure to tamoxifen, we considered the putative advantages of weekly administration... - Effects of bicalutamide and 4OH-tamoxifen on androgen-regulated gene expression in the LNCaP cell lineRosa Mangerini
Department of Medical Oncology, IRCCS SAN Martino Hospital IST National Cancer Research Institute, Largo R Benzi 10, 16132 Genoa, Italy
Anticancer Res 32:5323-9. 2012..Breast events are common adverse effects which can be effectively prevented by the concurrent administration of tamoxifen, a selective estrogen receptor modulator... - Switching trial of adjuvant tamoxifen with an aromatase inhibitor in postmenopausal patients with breast cancerFrancesco Boccardo
University and National Cancer Research Institute, Genoa, Italy
Clin Breast Cancer 5:S13-7. 2004..The updated results of previous trials and ongoing trials will soon establish criteria for selecting patients who might be better candidates for sequencing, and to fine tune strategies that are more appropriate... - HER2/neu oncoprotein overexpression in epithelial ovarian cancer: evaluation of its prevalence and prognostic significance. Clinical studyElena Verri
Academic Department of Medical Oncology, National Cancer Research Institute, Genoa, Italy
Oncology 68:154-61. 2005..CONCLUSION: In this study HER2/neu overexpression was associated with an increased risk of progression and death, especially among women with FIGO Stage I and II ovarian carcinoma... - Bicalutamide monotherapy versus flutamide plus goserelin in prostate cancer: updated results of a multicentric trialFrancesco Boccardo
Department of Medical Oncology, University and National Cancer Research Institute of Genoa, Largo R Benzi 10, 16132 Genoa, Italy
Eur Urol 42:481-90. 2002..To compare the efficacy of bicalutamide monotherapy to maximal androgen blockade in advanced prostatic cancer... - Switching to an aromatase inhibitor provides mortality benefit in early breast carcinoma: pooled analysis of 2 consecutive trialsFrancesco Boccardo
University and National Cancer Research Institute, Genoa, Italy
Cancer 109:1060-7. 2007..However, until now not all previous studies have shown a mortality benefit... - Serum enterolactone levels and mortality outcome in women with early breast cancer: a retrospective cohort studyPamela Guglielmini
Department of Oncology, Biology and Genetics, University of Genoa, Genoa, Italy
Breast Cancer Res Treat 132:661-8. 2012.... - Differential proteomic analysis of nuclear matrix in muscle-invasive bladder cancer: potential to improve diagnosis and prognosisPaola Barboro
National Cancer Research Institute, Genoa, Italy
Cell Oncol 30:13-26. 2008..Our aim was to identify nuclear matrix (NM) proteins that might serve to better characterize the phenotype of the invasive bladder cancer and to investigate their diagnostic and prognostic roles... - Chemotherapy versus tamoxifen versus chemotherapy plus tamoxifen in node-positive, oestrogen receptor-positive breast cancer patients. Very late results of the 'gruppo di ricerca per la chemio-ormonoterapia adiuvante (GROCTA)' 01-Trial in early breast canFrancesco Boccardo
Department of Oncology, Biology and Genetics, University of Genoa, Largo Rosanna Benzi 10, Genoa, Italy
Breast Cancer Res Treat 126:653-61. 2011.... - Prognostic value of cell cycle regulatory proteins in muscle-infiltrating bladder cancerFabia Galmozzi
Department of Medical Oncology, University of Genova, Genova, Italy
J Cancer Res Clin Oncol 132:757-64. 2006.... - Lymphedema microsurgical preventive healing approach for primary prevention of lower limb lymphedema after inguinofemoral lymphadenectomy for vulvar cancerMatteo Morotti
Department of Obstetrics and Gynecology, Department of Surgery, Unit of Lymphatic Surgery, and Service of Nuclear Medicine, S Martino Hospital, University of Genoa, Genoa, Italy
Int J Gynecol Cancer 23:769-74. 2013..This study describes the use of microsurgical lymphatic venous anastomosis (LVA) to prevent LLL in patients with vulvar cancer undergoing inguinofemoral lymph node dissection (ILND)... - Pediatric lymphedema and correlated syndromes: role of microsurgeryCorradino Campisi
Department of Surgery, Unit of Lymphatic Surgery and Microsurgery, San Martino Hospital, University of Genoa, Italy
Microsurgery 28:138-42. 2008..Better long-term results are obtained in earlier stages... 
Prognostic value of stromal and epithelial periostin expression in human prostate cancer: correlation with clinical pathological features and the risk of biochemical relapse or deathPier Vitale Nuzzo
IRCCS San Martino University Hospital IST National Cancer Research Institute and the University of Genoa, Academic Unit of Medical Oncology UOC Oncologia Medica B, Largo Rosanna Benzi 10, 16132 Genoa, Italy
BMC Cancer 12:625. 2012..The purpose of the present study was to evaluate the prognostic value of POSTN expression following prostatectomy...- Microsurgery for lymphedema: clinical research and long-term resultsCorradino Campisi
Department of Surgery, Unit of Lymphatic Surgery and Microsurgery, San Martino Hospital, University of Genoa, Italy
Microsurgery 30:256-60. 2010..To report the wide clinical experience and the research studies in the microsurgical treatment of peripheral lymphedema... - Lymphedema microsurgical preventive healing approach: a new technique for primary prevention of arm lymphedema after mastectomyFrancesco Boccardo
Department of Surgery, Unit of Lymphatic Surgery, S Martino Hospital, University of Genoa, 16132 Genoa, Italy
Ann Surg Oncol 16:703-8. 2009..The purpose of this manuscript is to assess the efficacy of direct lymphatic venous microsurgery in the prevention of lymphedema following axillary dissection for breast cancer... - Enterolactone in breast cyst fluid: correlation with EGF and breast cancer riskFrancesco Boccardo
Professorial Unit of Medical Oncology, University and National Cancer Research Institute, Genoa, Italy
Breast Cancer Res Treat 79:17-23. 2003..Our results show that enterolactone does accumulate in breast cysts, and that it modulates the risk related to the intracystic level of EGF, which is confirmed to be a strong predictor of breast cancer risk... - Peripheral lymphedema: new advances in microsurgical treatment and long-term outcomeCorradino Campisi
Department of Surgery, Lymphology and Microsurgery Center, S Martino Hospital, University of Genoa, Genoa, Italy
Microsurgery 23:522-5. 2003..With a follow-up even over 15 years after surgery, positive results from lymphatic microsurgery can be achieved in more than 80% of cases, especially in patients at precocious stages... - Epirubicin followed by cyclophosphamide, methotrexate and 5-fluorouracil versus paclitaxel followed by epirubicin and vinorelbine in patients with high-risk operable breast cancerFrancesco Boccardo
National Cancer Research Institute and the University of Genoa Largo Rosanna Benzi 10, IT 16132 Genoa, Italy
Oncology 78:274-81. 2010..Chemotherapy (CT), alone or combined with endocrine therapy (ET) in hormone receptor (HOR)-positive patients, is the standard for these women. However, there are still questions surrounding the optimal adjuvant CT regimen... - The lymphatics in the pathophysiology of thoracic and abdominal surgical pathology: immunological consequences and the unexpected role of microsurgeryFrancesco Boccardo
Department of Surgery, Unit of Lymphatic Surgery and Microsurgery, San Martino Hospital, University of Genoa, Genoa, Italy
Microsurgery 27:339-45. 2007..All patients had an improvement of their immunocompetence. Median follow-up was 5 years. We demonstrated that the use of microsurgery is remarkably advantageous for performing a causal treatment of the dysfunction... - Chemotherapy with cisplatin and 5-fluorouracil chronomodulated infusion in locally advanced or metastatic/recurrent carcinoma of the cervixLoredana Miglietta
Professorial Unit of Medical Oncology, National Cancer Research Institute, Genoa, Italy
Tumori 88:204-8. 2002.... - Diagnostic assessment and therapeutic approach for immunodeficiency due to chylous dysplasia: A case reportFrancesco Boccardo
Department of Surgery, Unit of Lymphatic Surgery and Microsurgery, San Martino Hospital, University of Genoa, Italy
Microsurgery 30:401-4. 2010..An accurate diagnostic assessment and above all lymphangiography allow to diagnose properly difficult cases of immunodeficiency due to intestinal protido-dispersion and to plan a correct therapeutic functional approach... - Histone deacetylase inhibitors enhance retinoid response in human breast cancer cell linesLaura Emionite
Department of Oncology, Biology and Genetics, University of Genova, Genova, Italy
Anticancer Res 24:4019-24. 2004..The efficacy of the retinoids/HDACIs combinations could represent a new strategy in breast cancer chemotherapy, allowing inhibition of both ER + and ER- cell populations... - Immunohistochemistry in non-immune hydrops fetalis: a single center experience in 79 fetusesCarlo Bellini
Neonatal Intensive Care Unit, Department of Pediatrics DIPE, Gaslini Institute, University of Genoa, Genova, Italy
Am J Med Genet A 152:1189-96. 2010..4%; P = 0.01). In conclusion, specific IHC staining techniques aimed at detecting lymphatic dysplasia are needed and should be mandatory in autopsies of fetuses with non-immune hydrops fetalis... - Microsurgery for treatment of peripheral lymphedema: long-term outcome and future perspectivesCorradino Campisi
Department of Surgery, Unit of Lymphatic Surgery and Microsurgery, San Martino Hospital, University of Genoa, Genoa, Italy
Microsurgery 27:333-8. 2007..Improved results can be expected with operations performed at earlier lymphedema stages... - Nuclear matrix protein expression in prostate cancer: possible prognostic and diagnostic applicationsPaola Barboro
National Cancer Research Institute, L.go R. Benzi 10, 1-16132 Genoa, Italy
Anticancer Res 25:3999-4004. 2005..In addition, a few newly-expressed proteins are significantly correlated with the risk of biochemical progression. The potential application of these proteins at the diagnostic and prognostic levels calls for further studies... - Diagnosis and management of primary chylous ascitesCorradino Campisi
Department of Surgery, Lymphatic Surgery and Microsurgery Unit, S. Martino Hospital, University of Genoa, Genoa, Italy
J Vasc Surg 43:1244-8. 2006..Our diagnostic work-up provided us with an exact diagnostic assessment and allowed us to plan a precise surgical approach... - Microsurgical techniques for lymphedema treatment: derivative lymphatic-venous microsurgeryCorradino Campisi
Department of Specialistic Surgical Sciences, Anesthesiology, and Organ Transplants, Section of General and Emergency Surgery, Lymphology and Microsurgery Center, S. Martino Hospital, University of Genoa, Genoa, Italy
World J Surg 28:609-13. 2004..Improved results can be expected with operations performed early, during the first stages of lymphedema... - Lymphatic complications in surgery: possibility of prevention and therapeutic optionsFrancesco Boccardo
Department of Surgery, University of Genoa, Lar Genoa, Italy
Updates Surg 64:211-6. 2012.... - Neurinoma originating from the recurrent nerve: report of a caseEmanuela Varaldo
Unità Operativa di Chirurgia Generale ad Indirizzo Endocrino, Universita degli Studi di Genova, Largo R Benzi 8, Genoa, Italy
Surg Today 38:633-4. 2008..This report describes an unusual case of recurrent nerve Schwannoma which was successfully identified by color Doppler sonography... - Secondary breast angiosarcoma: lethal response to anti-angiogenic therapy with paclitaxel chemotherapy. A case reportLaura Tomasello
Academic Department of Medical Oncology, National Cancer Research Institute, Genoa, Italy
Anticancer Res 26:4775-7. 2006..The authors report a case of cutaneous radiation-associated angiosarcoma treated with paclitaxel chemotherapy. A few days after drug administration, bleeding of skin lesions was observed and the patient died... - Impaired response to influenza vaccine associated with persistent memory B cell depletion in non-Hodgkin's lymphoma patients treated with rituximab-containing regimensDavide Bedognetti
Department of Oncology, Biology, and Genetics, University of Genoa, 16132 Genoa, Italy
J Immunol 186:6044-55. 2011.... - Lymphatic dysplasias in newborns and children: the role of lymphoscintigraphyCarlo Bellini
Neonatal Intensive Care Unit, Department of Pediatrics, University of Genoa, G Gaslini Institute, Genoa, Italy
J Pediatr 152:587-9, 589.e1-3. 2008..We suggest that lymphoscintigraphy is mandatory in all patients with signs of lymphatic dysplasia, including those with minimal and initial signs of lymphatic impairment, to obtain very early diagnosis and begin treatment... - Congenital pulmonary lymphangiectasiaCarlo Bellini
Neonatal Intensive Care Unit, Department of Pediatrics, University of Genoa, G, Gaslini Institute, Genoa, Italy
Orphanet J Rare Dis 1:43. 2006..Recent advances in intensive neonatal care have changed the previously nearly fatal outcome of PL at birth. Patients affected by PL who survive infancy, present medical problems which are characteristic of chronic lung disease... - [Prevention of lymphoedema secondary to the treatment of breast cancer: a case report and proposal for a prevention protocol]Corradino Campisi
Dipartimento di Chirurgia, Sezione di Chirurgia dei Linfatici e Microchirurgia, Ospedale S. Martino,
Chir Ital 56:419-24. 2004.... - Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormone-sensitive early-stage breast cancer: a meta-analysisWalter Jonat
University of Kiel, Germany
Lancet Oncol 7:991-6. 2006..We aimed to investigate whether switching treatment of postmenopausal women with such breast cancer to anastrozole after 2-3 years of tamoxifen would be more effective than continuing on tamoxifen for a total of 5 years... - Hennekam syndrome presenting as nonimmune hydrops fetalis, congenital chylothorax, and congenital pulmonary lymphangiectasiaCarlo Bellini
Servizio di Patologia Neonatale, Dipartimento di Pediatria DIPE, Universita di Genoa, Istituto G Gaslini, Largo G Gaslini, 16147 Genoa, Italy
Am J Med Genet A 120:92-6. 2003..Hydrops fetalis may be present in newborns with the Hennekam syndrome. Lymphoscintigraphy can be useful in explaining pleural-pulmonary involvement of this generalized lymph vessel malformation syndrome... - Impact of concurrent radiotherapy on chemotherapy total dose and dose intensity in patients with early breast cancerCristina Marenghi
University and National Cancer Research Institute of Genoa, Italy
Tumori 91:126-30. 2005..However, G-CSF support is required in a significant proportion of patients... - Differential expression of nuclear lamins in normal and cancerous prostate tissuesRosella Coradeghini
Istituto Nazionale per la Ricerca sul Cancro, I-16132 Genova, Italy
Oncol Rep 15:609-13. 2006.... - Lymphoscintigraphic evaluation of congenital lymphedema of the newbornCarlo Bellini
Neonatal Intensive Care Unit, Department of Pediatrics, the Institute G. Gaslini, University of Genova, Genova, Italy
Clin Nucl Med 27:383-4. 2002 - Nuclear matrix proteins changes in cancerous prostate tissues and their prognostic value in clinically localized prostate cancerFrancesco Boccardo
Professorial Unit of Medical Oncology, University and National Cancer Research Institute of Genoa, Italy
Prostate 55:259-64. 2003.... - Nonimmune idiopathic hydrops fetalis and congenital lymphatic dysplasiaCarlo Bellini
Servizio di Patologia Neonatale, Dipartimento di Pediatria DIPE, Universita di Genova, Istituto G Gaslini, Genova, Italia
Am J Med Genet A 140:678-84. 2006....