Research Topics
Genomes and Genes | Simona BoSummaryAffiliation: University of Turin Country: Italy Publications
| Collaborators
|
Detail Information
Publications
Associations between gamma-glutamyl transferase, metabolic abnormalities and inflammation in healthy subjects from a population-based cohort: a possible implication for oxidative stressSimona Bo
Dipartimento di Medicina Interna, Universitao di Torino, Corso Dogliotti 14, 10126 Torino, Italy
World J Gastroenterol 11:7109-17. 2005....
Is left ventricular hypertrophy a low-level inflammatory state? A population-based cohort studyS Bo
Department of Internal Medicine, University of Turin, Corso Dogliotti 14, 10126 Turin, Italy
Nutr Metab Cardiovasc Dis 22:668-76. 2012....- C-peptide and the risk for incident complications and mortality in type 2 diabetic patients: a retrospective cohort study after a 14-year follow-upS Bo
Department of Internal Medicine, University of Turin, Corso Dogliotti 14, 10126 Turin, Italy
Eur J Endocrinol 167:173-80. 2012..Our aim was to examine the associations between fasting C-peptide levels and all-cause mortality, specific-cause mortality and the incidence of chronic complications in patients with type 2 diabetes... - Does use of metformin protect against cancer in Type 2 diabetes mellitus?S Bo
Department of Internal Medicine, University of Turin, Italy
J Endocrinol Invest 35:231-5. 2012..In particular, metformin, the most frequently prescribed biguanide, is now considered a protective agent against cancer incidence and mortality in Type 2 diabetic patients... - Contributors to the obesity and hyperglycemia epidemics. A prospective study in a population-based cohortS Bo
Department of Internal Medicine, University of Turin, Turin, Italy
Int J Obes (Lond) 35:1442-9. 2011.... - Iron supplementation and gestational diabetes in midpregnancySimona Bo
Department of Internal Medicine, University of Turin, Corso Dogliotti 14, Turin 10126, Italy
Am J Obstet Gynecol 201:158.e1-6. 2009..Iron supplementation in pregnancy seems beneficial for neonatal/maternal outcomes, but it was associated with diabetes and hypertension in the general population... - Prevalence of undiagnosed metabolic syndrome in a population of adult asymptomatic subjectsSimona Bo
Department of Internal Medicine, University of Turin, Corso Dogliotti 14, 10126 Torino, Italy
Diabetes Res Clin Pract 75:362-5. 2007..To evaluate in the general population the prevalence of undiagnosed metabolic syndrome (MS), defined according to the National Cholesterol Education Program (NCEP) and International Diabetes Federation (IDF) criteria... - Insulin resistance in pre-school very-low-birth weight pre-term childrenS Bo
Department of Internal Medicine, University of Turin, Italy
Diabetes Metab 32:151-8. 2006.... - Associations between serum uric acid and adipokines, markers of inflammation, and endothelial dysfunctionS Bo
Department of Internal Medicine, University of Turin, 10126 Turin, Italy
J Endocrinol Invest 31:499-504. 2008..The aim of the study was to evaluate the association between uric acid and adipokines, markers of inflammation, oxidative stress, and endothelial dysfunction, which are all linked to cardiovascular disease... - Does C-reactive protein identify a subclinical metabolic disease in healthy subjects?S Bo
University of Turin, Turin, Italy
Eur J Clin Invest 35:265-70. 2005.... - Should we consider gestational diabetes a vascular risk factor?S Bo
Department of Internal Medicine, University of Turin, Corso Dogliotti 14, 10126 Torino, Italy
Atherosclerosis 194:e72-9. 2007..Post-GDM women, despite being currently free from metabolic abnormalities, showed higher values of markers of endothelial dysfunction and IMT than controls, consistent with an increased future cardiovascular risk... - Magnesium intake, glucose and insulin serum levels in pre-school very-low-birth weight pre-term childrenSimona Bo
Department of Internal Medicine, University of Turin, Corso Dogliotti 14, 10126 Turin, Italy
Nutr Metab Cardiovasc Dis 17:741-7. 2007..To evaluate cross-sectional associations between dietary magnesium intake and the metabolic pattern of very-low-birth-weight (VLBW, <1500 g) pre-term children, in pre-school years (>2 and <6 years)... - High-normal blood pressure is associated with a cluster of cardiovascular and metabolic risk factors: a population-based studySimona Bo
Department of Internal Medicine, University of Turin, Turin, Italy
J Hypertens 27:102-8. 2009..Increased inflammation, endothelial dysfunction, oxidative stress, and reduced adiponectin values have sporadically been reported in these patients... 
Effectiveness of a lifestyle intervention on metabolic syndrome. A randomized controlled trialSimona Bo
Department of Internal Medicine, University of Turin, Turin, Italy
J Gen Intern Med 22:1695-703. 2007..Intensive lifestyle intervention significantly reduces the progression to diabetes in high-risk individuals...- What predicts the occurrence of the metabolic syndrome in a population-based cohort of adult healthy subjects?S Bo
Department of Internal Medicine, University of Turin, Italy
Diabetes Metab Res Rev 25:76-82. 2009..Predictors of MS were previously evaluated in patients without the full syndrome, but with some of its traits. This might confound the resulting associations... - Role of dietary magnesium in cardiovascular disease prevention, insulin sensitivity and diabetesSimona Bo
Department of Internal Medicine, University of Turin, Italy
Curr Opin Lipidol 19:50-6. 2008..Controversy due to contrasting results in the literature is also discussed... - Associations of dietary and serum copper with inflammation, oxidative stress, and metabolic variables in adultsSimona Bo
Department of Internal Medicine, University of Turin, 10126 Turin, Italy
J Nutr 138:305-10. 2008..001). Marginal copper deficiency is associated with an unfavorable metabolic pattern, but copper supplementation might not be recommended in view of its association with inflammation and markers of oxidative stress... - Plasma visfatin concentrations after a lifestyle intervention were directly associated with inflammatory markersS Bo
Department of Internal Medicine, University of Turin, Corso Dogliotti 14, Turin 10126, Italy
Nutr Metab Cardiovasc Dis 19:423-30. 2009..The biological activity and regulation of the novel adipokine visfatin are still largely unknown. Our aim was to evaluate if visfatin plasma concentrations may be influenced by a lifestyle intervention... - Mortality within the first 10 years of the disease in type 2 diabetic patientsS Bo
Department of Internal Medicine, University of Torino, Corso Dogliotti 14, 10126 Torino, Italy
Nutr Metab Cardiovasc Dis 16:8-12. 2006..The aim of this study was to evaluate pattern and predictors of mortality after a 4.5 year follow-up in a cohort of type 2 diabetic patients, according to diabetes duration... - C-reactive protein and tumor necrosis factor-alpha in gestational hyperglycemiaS Bo
Department of Internal Medicine, University of Turin, Italy
J Endocrinol Invest 28:779-86. 2005.... - Effects of TCF7L2 polymorphisms on glucose values after a lifestyle interventionSimona Bo
Department of Internal Medicine and the Unit of Cancer Epidemiology, University of Turin, Turin, Italy
Am J Clin Nutr 90:1502-8. 2009..Few intervention studies have shown that it has negative effects on metabolic improvement after lifestyle programs... - Cancer mortality reduction and metformin: a retrospective cohort study in type 2 diabetic patientsS Bo
Department of Internal Medicine, University of Torino, Turin, Italy
Diabetes Obes Metab 14:23-9. 2012..The mortality rates were compared with the general population from the same area... - Obesity or diabetes: what is worse for the mother and for the baby?S Bo
Department of Internal Medicine, University of Turin, Italy
Diabetes Metab 29:175-8. 2003.... 
Implementing hospital guidelines improves warfarin use in non-valvular atrial fibrillation: a before-after studySimona Bo
Department of Internal Medicine, University of Torino, Italy
BMC Public Health 7:203. 2007..We aimed to evaluate whether implementing guidelines on antithrombotic therapy (AT) by a multifaceted strategy may improve appropriateness of its prescription in NVAF-patients discharged from a large tertiary-care hospital...- Mild gestational hyperglycemia, the metabolic syndrome and adverse neonatal outcomesSimona Bo
Department of Internal Medicine, University of Turin, Turin, Italy
Acta Obstet Gynecol Scand 83:335-40. 2004..The aim of this study was to evaluate the prevalence of the metabolic syndrome and its effect on neonatal outcomes in pregnancies with different degrees of hyperglycemia... - Isolated systolic hypertension in a cohort of type 2 diabetic patientsS Bo
Department of Internal Medicine, University of Turin, Turin, Italy
Nutr Metab Cardiovasc Dis 14:157-61. 2004..The aim of this study was to evaluate the prevalence and role of isolated and borderline isolated systolic hypertension in a cohort of 3892 type 2 diabetic patients... - Prior gestational hyperglycemia: a long-term predictor of the metabolic syndromeS Bo
Department of Internal Medicine, University of Turin, Italy
J Endocrinol Invest 27:629-35. 2004.... - Diet or exercise: what is more effective in preventing or reducing metabolic alterations?Simona Bo
Department of Internal Medicine, University of Turin, Corso Dogliotti 14, 10126 Turin, Italy
Eur J Endocrinol 159:685-91. 2008.... - Patients with type 2 diabetes had higher rates of hospitalization than the general populationSimona Bo
Department of Internal Medicine, University of Torino, Corso Dogliotti 14, 10126 Torino, Italy
J Clin Epidemiol 57:1196-201. 2004..We describe the rate, causes, and predictors of hospitalization for all patients with type 2 diabetes in a diabetes clinic in Turin, Italy and compare their hospitalization rates with those of the general population... - Magnesium and trace element intake after a lifestyle interventionSimona Bo
Department of Internal Medicine, University of Turin, Turin, Italy
Nutrition 27:108-10. 2011..Our objective was to evaluate whether a lifestyle intervention trial, aimed at reducing total and saturated fat and increasing fiber intake, can affect also the intake of selenium (Se), zinc (Zn), copper (Cu), chromium (Cr), and Mg... - Gestational hyperglycemia, zinc, selenium, and antioxidant vitaminsSimona Bo
Department of Internal Medicine, University of Turin, Turin, Italy
Nutrition 21:186-91. 2005..This study evaluated the dietary intake of antioxidant vitamins, zinc, selenium, and serum levels of zinc and selenium in women with gestational hyperglycemia and normoglycemia... - The metabolic syndrome and high C-reactive protein: prevalence and differences by sex in a southern-European population-based cohortSimona Bo
Department of Internal Medicine, University of Turin, Italy
Diabetes Metab Res Rev 21:515-24. 2005..To evaluate the prevalence of the metabolic syndrome (MS) and its components in a population-based cohort, and to analyse the association between gender, environmental conditions, C-reactive protein (CRP), and the syndrome... - Relationships between human serum resistin, inflammatory markers and insulin resistanceS Bo
Department of Internal Medicine, University of Turin, Turin, Italy
Int J Obes (Lond) 29:1315-20. 2005..This study investigates associations between serum resistin levels and markers of insulin resistance, inflammation (C-reactive protein (CRP)) and of oxidative stress (nytrotirosine (NT))... - Plasma nitrotyrosine levels, antioxidant vitamins and hyperglycaemiaS Bo
Department of Internal Medicine, University of Turin, Turin, Italy
Diabet Med 22:1185-9. 2005..The aim of this paper is to evaluate the association between plasma NT levels and glucose tolerance status, according to antioxidant vitamin intakes... - Dietary magnesium and fiber intakes and inflammatory and metabolic indicators in middle-aged subjects from a population-based cohortSimona Bo
Department of Internal Medicine, University of Turin, Turin, Italy, and the Diabetic Clinic, Hospital of Asti, Italy
Am J Clin Nutr 84:1062-9. 2006..Lower magnesium and fiber intakes were linked to hs-CRP >/= 3 mg/L in both the entire cohort and healthy persons... - Nitrosative stress predicts the presence and severity of nonalcoholic fatty liver at different stages of the development of insulin resistance and metabolic syndrome: possible role of vitamin A intakeGiovanni Musso
Emergency Medicine Department, Gradenigo Hospital, Turin, Italy
Am J Clin Nutr 86:661-71. 2007..Diet, adipokines, and nitrosative stress have been linked to both NAFLD and insulin resistance... - Loxin polymorphism is associated with increased resistin levels and with oxidative statusRoberto Gambino
Department of Internal Medicine, University of Turin, Corso Dogliotti 14, 10126 Torino, Italy
Clin Biochem 44:1015-7. 2011..We hypothesized that LOX-1 polymorphism may impact on inflammation and cardiovascular risk by modulating systemic resistin expression... - Transcription factor 7-like 2 (TCF7L2) polymorphism and hyperglycemia in an adult Italian population-based cohortRoberto Gambino
Department of Internal Medicine, University of Turin, Torino, Italy
Diabetes Care 33:1233-5. 2010..To assess whether TCF7L2 polymorphism has a role in the deterioration of glycemic control... - Low HDL-cholesterol: a component of the metabolic syndrome only in the presence of fasting hypertriglyceridemia in type 2 diabetic patientsS Bo
Department of Internal Medicine, University of Torino, Torino, Italy
Diabetes Metab 27:31-5. 2001..These results indicate that low HDL-cholesterol is a component of the metabolic syndrome only in the presence of fasting hypertriglyceridemia in type 2 diabetic patients... - Type 2 diabetes mellitus and chronic hepatitis C: which is worse? Results of a long-term retrospective cohort studyChiara Giordanino
Division of Gastroenterology, University of Turin, San Luigi Medical School, Orbassano, Italy
Dig Liver Dis 44:406-12. 2012.... - Microsomal triglyceride transfer protein 493-T variant is associated with resistin levels and C-reactive proteinRoberto Gambino
Department of Internal Medicine, University of Torino, 10126 Torino, Italy
Clin Biochem 40:1219-24. 2007..We hypothesized that MTP polymorphism could be associated to LDL-cholesterol levels and proinflammatory cytokines, such as resistin... - Type 1 autoimmune hepatitis and adipokines: new markers for activity and disease progression?Marilena Durazzo
Department of Internal Medicine, University of Turin, Turin, Italy
J Gastroenterol 44:476-82. 2009..There is some evidence suggesting a link between adiponectin-biliary function and liver disease. The aim of this study was to clarify the behavior of adipokines in autoimmune hepatitis type 1... - Incidence of type 2 diabetes mellitus and glucose abnormalities in patients with chronic hepatitis C infection by response to treatment: results of a cohort studyChiara Giordanino
Gastroenterology, Molinette Hospital, Turin, Italy
Am J Gastroenterol 103:2481-7. 2008..Patients with chronic hepatitis C are at risk of developing type 2 diabetes mellitus (DM) and impaired fasting glucose (IFG), and this risk may increase among hepatitis C virus (HCV) patients not responding to an antiviral therapy... - Prognostic implications for insulin-sensitive and insulin-resistant normal-weight and obese individuals from a population-based cohortSimona Bo
Department of Internal Medicine, University of Turin, Turin, Italy
Am J Clin Nutr 96:962-9. 2012..There are few prospective data on the prognosis of insulin-sensitive and insulin-resistant normal-weight (NW) or obese individuals... - The metabolic syndrome in twins: a consequence of low birth weight or of being a twin?S Bo
Department of International Medicine, University of Torino, Torino, Italy
Exp Clin Endocrinol Diabetes 109:135-40. 2001..To evaluate if being a twin is a condition at risk of developing metabolic abnormalities in the adult life 'per se' or as a consequence of the lower birth weight... - Dietary fat and gestational hyperglycaemiaS Bo
Department of Internal Medicine, University of Turin, Italy
Diabetologia 44:972-8. 2001..This role is more important in the absence of conventional risk factors suggesting that glucose abnormalities could be prevented during pregnancy, at least in some groups of women... - Maternal low birth weight and gestational hyperglycemiaS Bo
Department of Internal Medicine, University of Torino, Italy
Gynecol Endocrinol 17:133-6. 2003..82, 95% CI 0.74-0.91) in a multiple logistic regression model. These findings suggest that women with low birth weight constitute a group at increased risk for both gestational impaired glucose tolerance and diabetes... - Renal damage in patients with Type 2 diabetes: a strong predictor of mortalityS Bo
Department of Internal Medicine, University of Torino, Turin, Italy
Diabet Med 22:258-65. 2005.... - Overlap syndromes of autoimmune hepatitis: an open questionMarilena Durazzo
Department of Internal Medicine, University of Turin, C so A M Dogliotti 14, 10126, Turin, Italy
Dig Dis Sci 58:344-8. 2013..The diagnostic scores for autoimmune hepatitis can help for diagnosis, even though their definitive soundness is lacking... - Extreme regression models for characterizing high-cost patientsDario Gregori
Department of Public Health and Microbiology, University of Turin, Turin, Italy
J Eval Clin Pract 15:164-71. 2009..Information on factors that predict high expenditures is of interest in healthcare planning. The aim of this paper was to inspect the behaviour of extreme regression (ER) models... - Clinical characteristics and outcome of pregnancy in women with gestational hyperglycaemia with and without antibodies to beta-cell antigensS Bo
Department of Internal Medicine, University of Turin, Turin, Italy
Diabet Med 20:64-8. 2003..If this conclusion is corroborated by the follow-up of larger series, clinical and immunological distinction of types of gestational hyperglycaemia would be useful... - Focus on therapeutic strategies of nonalcoholic Fatty liver diseaseMarilena Durazzo
Department of Internal Medicine, University of Turin, 10127 Turin, Italy
Int J Hepatol 2012:464706. 2012..This paper is focused on the treatments used for NAFLD and the potential new therapy... - Alterations of seminal and hormonal parameters: An extrahepatic manifestation of HCV infection?Marilena Durazzo
Department of Internal Medicine, Corso A M Dogliotti 14, 10126, Turin, Italy
World J Gastroenterol 12:3073-6. 2006..To evaluate the possible influences of HCV infection and relative antiviral treatment on seminal parameters and reproductive hormonal serum levels... - Comparison of two enzyme immunometric assays to measure tumor necrosis factor-alpha in human serumR Gambino
Department of Internal Medicine, University of Turin, Italy
Clin Chim Acta 364:349-53. 2006.... - Evaluating hospital costs in type 2 diabetes care: does the choice of the model matter?D Gregori
Department of Public Health and Microbiology, University of Turin, Italy
Curr Med Res Opin 22:1965-71. 2006..Awareness of the economic burden of diabetes has led to a number of studies on economic issues. However, comparison among cost-of-illness studies is problematic because different methods are used to arrive at a final cost estimate... - Hypouricemia and hyperuricemia in type 2 diabetes: two different phenotypesS Bo
Department of Internal Medicine, University of Torino, Torino, Italy
Eur J Clin Invest 31:318-21. 2001.... - Effects of interferon alpha (INF-alpha) therapy on peripheral blood lymphocyte subsets from FIV and FeLV naturally infected catsF Riondato
Department of Animal Pathology, Faculty of Veterinary Medicine, University of Torino, Grugliasco, Italy
Vet Res Commun 27:429-32. 2003 - Should nonalcoholic fatty liver disease be included in the definition of metabolic syndrome? A cross-sectional comparison with Adult Treatment Panel III criteria in nonobese nondiabetic subjectsGiovanni Musso
Gradenigo Hospital, Corso R Margherita 8, 10132 Turin, Italy
Diabetes Care 31:562-8. 2008..We compared the strength of the associations of ATP III criteria and of NAFLD to insulin resistance, oxidative stress, and endothelial dysfunction in nonobese nondiabetic subjects...