Research Topics
| Albertino BigianiSummaryAffiliation: University of Modena and Reggio Emilia Country: Italy Publications
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Detail Information
Publications
Localization of amiloride-sensitive sodium current and voltage-gated calcium currents in rat fungiform taste cellsAlbertino Bigiani
Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, Modena, Italy
J Neurophysiol 98:2483-7. 2007..Our findings on sodium taste detection support the recent model of taste transduction, involving separate groups of taste cells: chemosensitive cells and cells forming conventional synapses...- Channels as taste receptors in vertebratesAlbertino Bigiani
Dipartimento di Scienze Biomediche, Sezione di Fisiologia, Universita di Modena e Reggio Emilia, Via Campi 287, 41100 Modena, Italy
Prog Biophys Mol Biol 83:193-225. 2003..In this review, we focus on the functional and molecular properties of ion channels that serve as receptors in taste transduction... - Functional correlates of somatostatin receptor 2 overexpression in the retina of mice with genetic deletion of somatostatin receptor 1Albertino Bigiani
Dipartimento di Scienze Biomediche, Sezione di Fisiologia, Università di Modena e Reggio Emilia via Campi 287, 41100 Modena, Italy
Brain Res 1025:177-85. 2004..The level of expression of sst(2) receptors may therefore represent a key step in the regulation of sst(2) receptor-mediated responses, at least in the retina... - Effect of ciguatoxin 3C on voltage-gated Na+ and K+ currents in mouse taste cellsValeria Ghiaroni
Dipartimento di Scienze Biomediche, , Via Campi 287, 41100 Modena, Italy
Chem Senses 31:673-80. 2006..Our data suggest that taste disturbances reported in ciguatera poisoning might be due to the ability of ciguatera toxins to interfere with ion channels in taste buds... 
Apical and basal neurones isolated from the mouse vomeronasal organ differ for voltage-dependent currentsFrancesca Fieni
Dipartimento di Scienze Biomediche, Sezione di Fisiologia, , Via Campi 287, 41100 Modena, Italy
J Physiol 552:425-36. 2003..Our findings indicate that apical and basal neurones in the VNO exhibit distinct electrical properties. This might have a profound effect on the sensory processes occurring in the VNO during pheromone detection...- Electrophysiological heterogeneity in a functional subset of mouse taste cells during postnatal developmentValeria Ghiaroni
Dipartimento di Scienze Biomediche, Sezione di Fisiologia, , 41100 Modena, Italy
Chem Senses 28:827-33. 2003..Our findings indicate a mechanism that contributes to building-up the functional heterogeneity of mammalian taste cells during the postnatal development... - Ion conductances in supporting cells isolated from the mouse vomeronasal organValeria Ghiaroni
Dipartimento di Scienze Biomediche, , Italy
J Neurophysiol 89:118-27. 2003..Therefore vomeronasal supporting cells could affect chemosensory transduction in the VNO by regulating the ionic strength of the pheromone-containing medium... - Postnatal development of membrane excitability in taste cells of the mouse vallate papillaAlbertino Bigiani
Dipartimento di Scienze Biomediche, Sezione di Fisiologia, Universita di Modena e Reggio Emilia, 41100 Modena
J Neurosci 22:493-504. 2002..These functional changes may have a profound impact on the transduction capabilities of taste buds during development... - Inhibition of voltage-gated potassium currents by gambierol in mouse taste cellsValeria Ghiaroni
Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, 41100 Modena, Italy
Toxicol Sci 85:657-65. 2005..Thus, gambierol may alter action potential discharge in taste cells and this could be associated with the taste alterations reported in the clinical literature... - Electrophysiology of Necturus taste cellsAlbertino Bigiani
Dipartimento di Scienze Biomediche, Sezione di Fisiologia, Universita di Modena e Reggio Emilia, Via Campi 287, Italy
Prog Neurobiol 66:123-59. 2002.... - Activation of an efferent cholinergic pathway produces strong protection against myocardial ischemia/reperfusion injury in ratsChiara Mioni
Department of Biomedical Sciences, Sections of Pharmacology, University of Modena and Reggio Emilia, Modena, Italy
Crit Care Med 33:2621-8. 2005..These data suggest that melanocortins and pertinent compounds able to activate such a pathway could provide the potential for development of a new class of drugs for a novel approach to management of ischemic heart disease... 
Proteomic analysis reveals multiple patterns of response in cells exposed to a toxin mixtureGian Luca Sala
Centro Interdisciplinare di Scienze e Tecnologie per la Qualità e Sicurezza degli Alimenti, Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, I 41100 Modena, Italy
Chem Res Toxicol 22:1077-85. 2009..Multiple patterns of responses to the toxin mixture were recorded in the two sets, consisting of both independent and interacting actions, among which we detected synergistic, similar, and antagonistic effects...- Efferent vagal fibre stimulation blunts nuclear factor-kappaB activation and protects against hypovolemic hemorrhagic shockSalvatore Guarini
Department of Biomedical Sciences, Section of Pharmacology, University of Modena and Reggio Emilia, Modena, Italy
Circulation 107:1189-94. 2003..CONCLUSIONS: Our results show a parasympathetic inhibition of NF-kappaB by which the brain opposes NF-kappaB activation in the liver and modulates the inflammatory response during acute hypovolemic hemorrhagic shock... - Palytoxin induces cell lysis by priming a two-step process in mcf-7 cellsSimone Prandi
Dipartimento di Scienze Biomediche, Università di Modena e Reggio Emilia, Via Campi 287, I 41125 Modena, Italy
Chem Res Toxicol 24:1283-96. 2011..A model of the two-step process of PlTX-induced cytolysis is presented... - Palytoxin action on the Na(+),K(+)-ATPase and the disruption of ion equilibria in biological systemsGian Paolo Rossini
Dipartimento di Scienze Biomediche, Universita di Modena e Reggio Emilia, via G Campi 287, I 41125 Modena, Italy
Toxicon 57:429-39. 2011.... - Adrenocorticotropin reverses hemorrhagic shock in anesthetized rats through the rapid activation of a vagal anti-inflammatory pathwaySalvatore Guarini
Department of Biomedical Sciences, Section of Pharmacology, University of Modena and Reggio Emilia, via G Campi 287, 41100 Modena, Italy
Cardiovasc Res 63:357-65. 2004.... - How proteins come together in the plasma membrane and function in macromolecular assemblies: focus on receptor mosaicsLuigi F Agnati
Department of Biomedical Sciences, Section of Physiology, University of Modena and Reggio Emilia, 41100 Modena, Italy
J Mol Neurosci 26:133-54. 2005..The oscillation in the intensity of the dipole caused by the action potentials opens the possibility of an interaction among dipoles by electromagnetic waves... - Activation of the cholinergic anti-inflammatory pathway reduces NF-kappab activation, blunts TNF-alpha production, and protects againts splanchic artery occlusion shockDomenica Altavilla
Department of Clinical and Experimental Medicine and Pharmacology, Section of Pharmacology, University of Messina, Messina Italy
Shock 25:500-6. 2006..2 +/- 0.6 U/g tissue). Chlorisondamine, a nicotinic receptor antagonist, abated the effects of vagal stimulation. Our results show a parasympathetic inhibition of nuclear factor-kappaB and TNF-alpha in SAO shock...