Research Topics

Paolo Bianco


Affiliation: University of Rome La Sapienza
Country: Italy


  1. Bianco P, Robey P, Saggio I, Riminucci M. "Mesenchymal" stem cells in human bone marrow (skeletal stem cells): a critical discussion of their nature, identity, and significance in incurable skeletal disease. Hum Gene Ther. 2010;21:1057-66 pubmed publisher
  2. Bianco P, Robey P. Skeletal stem cells. Development. 2015;142:1023-7 pubmed publisher
    ..Here and in the accompanying poster, we concisely discuss the biology of SSCs in the context of the development and postnatal physiology of skeletal lineages, to which their use in medicine must remain anchored. ..
  3. Bianco P, Barker R, Brüstle O, Cattaneo E, Clevers H, Daley G, et al. Regulation of stem cell therapies under attack in Europe: for whom the bell tolls. EMBO J. 2013;32:1489-95 pubmed publisher
  4. Bianco P. "Mesenchymal" stem cells. Annu Rev Cell Dev Biol. 2014;30:677-704 pubmed publisher
    ..Here, I discuss how the two views developed, conceptually and experimentally, and attempt to clarify the confusion arising from their collision. ..
  5. Bianco P. Stem cells and bone: a historical perspective. Bone. 2015;70:2-9 pubmed publisher
    ..Current interest in stem cells in bone as in other fields is intertwined with that shift. New opportunities and also new challenges arise. This article is part of a Special Issue entitled "Stem cells and bone". ..
  6. Kassem M, Bianco P. Skeletal stem cells in space and time. Cell. 2015;160:17-9 pubmed publisher
    ..and Worthley et al. demonstrate that a stem cell for skeletal tissues, and a system of more restricted, downstream progenitors, can be identified in mice and demonstrate its role in skeletal tissue maintenance and regeneration. ..
  7. Bianco P, Cao X, Frenette P, Mao J, Robey P, Simmons P, et al. The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine. Nat Med. 2013;19:35-42 pubmed publisher
    ..These uncertainties have a major impact on their envisioned therapeutic use. ..