M Bernardi

Summary

Affiliation: University of Bologna
Country: Italy

Publications

  1. doi request reprint Albumin infusion in patients undergoing large-volume paracentesis: a meta-analysis of randomized trials
    Mauro Bernardi
    Dipartimento di Medicina Clinica, Alma Mater Studiorum Universita di Bologna, Semeiotica Medica Policlinico S Orsola Malpighi, Bologna, Italy
    Hepatology 55:1172-81. 2012
  2. doi request reprint Spontaneous bacterial peritonitis: from pathophysiology to prevention
    Mauro Bernardi
    Dipartimento di Medicina Clinica, Alma Mater Studiorum, Semeiotica Medica, Policlinico S Orsola Malpighi, University of Bologna, Via Albertoni, 15, 40138, Bologna, Italy
    Intern Emerg Med 5:S37-44. 2010
  3. doi request reprint QT interval prolongation in liver cirrhosis: innocent bystander or serious threat?
    Mauro Bernardi
    Unità Operativa Semeiotica Medica, Department of Clinical Medicine, Alma Mater Studiorum University of Bologna, Via Albertoni 15, Bologna 40138, Italy
    Expert Rev Gastroenterol Hepatol 6:57-66. 2012
  4. doi request reprint The MELD score in patients awaiting liver transplant: strengths and weaknesses
    Mauro Bernardi
    Semeiotica Medica, Dipartimento di Medicina Clinica, Alma Mater Studiorum Universita di Bologna, Italy
    J Hepatol 54:1297-306. 2011
  5. ncbi request reprint [The unifying hypothesis on the regulation of body fluid volume. Physiology and pathophysiology of fluid homeostasis, with particular regard to cardiac decompensation and hepatic cirrhosis]
    M Bernardi
    Unità di Semeiotica Medica, Dipartimento di Medicina Interna, Cardioangiologia, Epatologia, Alma Mater Studiorum, Universita degli Studi di Bologna, Bologna
    Minerva Anestesiol 71:1-9. 2005
  6. ncbi request reprint Low replication and variability of HBV pre-core in concomitant infection with hepatitis B and hepatitis C viruses
    M S De Mitri
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Bologna, Italy
    Arch Virol 152:395-404. 2007
  7. ncbi request reprint In vitro effect of thymosin-alpha1 and interferon-alpha on Th1 and Th2 cytokine synthesis in patients with chronic hepatitis C
    P Andreone
    Semeiotica Medica, Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, Universita di Bologna, Policlinico S Orsola, Via Massarenti, 9 40138 Bologna, Italy
    J Viral Hepat 8:194-201. 2001
  8. ncbi request reprint Clinical trial: peg-interferon alfa-2b and ribavirin for the treatment of genotype-1 hepatitis C recurrence after liver transplantation
    F Lodato
    Department of Digestive Diseases and Internal Medicine, Azienda Ospedaliero Universitaria Policlinico Sant Orsola Malpighi, Bologna, Italy
    Aliment Pharmacol Ther 28:450-7. 2008
  9. doi request reprint Hepatitis C Virus-related chronic liver disease in elderly patients: an Italian cross-sectional study
    A Gramenzi
    Dipartimento di Medicina Clinica, Alma Mater Studiorum Universita di Bologna, Semeiotica Medica, Azienda Ospedaliero Universitaria di Bologna, Policlinico S Orsola Malpighi, Bologna, Italy
    J Viral Hepat 17:360-6. 2010
  10. ncbi request reprint Food deprivation exacerbates mitochondrial oxidative stress in rat liver exposed to ischemia-reperfusion injury
    M Domenicali
    Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia e, Rianimatorie e dei Trapianti, University of Bologna, 40138 Bologna, Italy
    J Nutr 131:105-10. 2001

Detail Information

Publications78

  1. doi request reprint Albumin infusion in patients undergoing large-volume paracentesis: a meta-analysis of randomized trials
    Mauro Bernardi
    Dipartimento di Medicina Clinica, Alma Mater Studiorum Universita di Bologna, Semeiotica Medica Policlinico S Orsola Malpighi, Bologna, Italy
    Hepatology 55:1172-81. 2012
    ..98). Conclusions: This meta-analysis provides evidence that albumin reduces morbidity and mortality among patients with tense ascites undergoing large-volume paracentesis, as compared with alternative treatments investigated thus far...
  2. doi request reprint Spontaneous bacterial peritonitis: from pathophysiology to prevention
    Mauro Bernardi
    Dipartimento di Medicina Clinica, Alma Mater Studiorum, Semeiotica Medica, Policlinico S Orsola Malpighi, University of Bologna, Via Albertoni, 15, 40138, Bologna, Italy
    Intern Emerg Med 5:S37-44. 2010
    ..Fluoroquinolones are commonly employed, but the frequent occurrence of resistant bacterial strains make third generation cephalosporins preferable in specific settings. The high PBS recurrence indicates secondary antibiotic prophylaxis...
  3. doi request reprint QT interval prolongation in liver cirrhosis: innocent bystander or serious threat?
    Mauro Bernardi
    Unità Operativa Semeiotica Medica, Department of Clinical Medicine, Alma Mater Studiorum University of Bologna, Via Albertoni 15, Bologna 40138, Italy
    Expert Rev Gastroenterol Hepatol 6:57-66. 2012
    ....
  4. doi request reprint The MELD score in patients awaiting liver transplant: strengths and weaknesses
    Mauro Bernardi
    Semeiotica Medica, Dipartimento di Medicina Clinica, Alma Mater Studiorum Universita di Bologna, Italy
    J Hepatol 54:1297-306. 2011
    ..For others, such as persistent ascites and hyponatremia, attempts to improve MELD's predicting power are currently underway, but await definite validation...
  5. ncbi request reprint [The unifying hypothesis on the regulation of body fluid volume. Physiology and pathophysiology of fluid homeostasis, with particular regard to cardiac decompensation and hepatic cirrhosis]
    M Bernardi
    Unità di Semeiotica Medica, Dipartimento di Medicina Interna, Cardioangiologia, Epatologia, Alma Mater Studiorum, Universita degli Studi di Bologna, Bologna
    Minerva Anestesiol 71:1-9. 2005
  6. ncbi request reprint Low replication and variability of HBV pre-core in concomitant infection with hepatitis B and hepatitis C viruses
    M S De Mitri
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Bologna, Italy
    Arch Virol 152:395-404. 2007
    ..005). In conclusion, in HBV/HCV infection, the virological pattern was characterised by the dominance of HCV associated with lower HBV replication capacity and decreased emergence of HBV pre-C variants...
  7. ncbi request reprint In vitro effect of thymosin-alpha1 and interferon-alpha on Th1 and Th2 cytokine synthesis in patients with chronic hepatitis C
    P Andreone
    Semeiotica Medica, Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, Universita di Bologna, Policlinico S Orsola, Via Massarenti, 9 40138 Bologna, Italy
    J Viral Hepat 8:194-201. 2001
    ....
  8. ncbi request reprint Clinical trial: peg-interferon alfa-2b and ribavirin for the treatment of genotype-1 hepatitis C recurrence after liver transplantation
    F Lodato
    Department of Digestive Diseases and Internal Medicine, Azienda Ospedaliero Universitaria Policlinico Sant Orsola Malpighi, Bologna, Italy
    Aliment Pharmacol Ther 28:450-7. 2008
    ..Treatment of hepatitis C virus (HCV) recurrence after liver transplantation (LT) is difficult with low response rates...
  9. doi request reprint Hepatitis C Virus-related chronic liver disease in elderly patients: an Italian cross-sectional study
    A Gramenzi
    Dipartimento di Medicina Clinica, Alma Mater Studiorum Universita di Bologna, Semeiotica Medica, Azienda Ospedaliero Universitaria di Bologna, Policlinico S Orsola Malpighi, Bologna, Italy
    J Viral Hepat 17:360-6. 2010
    ..003). Our results further emphasize the notion that chronic hepatitis C is becoming a disease of the elderly and that elderly patients with chronic HCV infection often have severe and underestimated disease...
  10. ncbi request reprint Food deprivation exacerbates mitochondrial oxidative stress in rat liver exposed to ischemia-reperfusion injury
    M Domenicali
    Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia e, Rianimatorie e dei Trapianti, University of Bologna, 40138 Bologna, Italy
    J Nutr 131:105-10. 2001
    ..01). Food deprivation was associated with greater mitochondrial oxidative injury in rat livers exposed to warm ischemia-reperfusion, and the extent of oxidative damage in mitochondria increased with the length of food deprivation...
  11. ncbi request reprint Successful treatment of CCL4-induced acute liver failure with portal vein arterialization in the rat
    B Nardo
    Department of Surgery and Transplantations, S Orsola Malpighi Hospital, University of Bologna, Italy
    Transplant Proc 38:1187-9. 2006
    ..This study sought to determine whether portal vein arterialization (PVA), which increases the oxygen supply to the liver, was protective in a rat model of liver failure...
  12. ncbi request reprint Pegylated interferon plus ribavirin for recurrent Hepatitis C infection after liver transplantation in naïve and non-responder patients on a stable immunosuppressive regimen
    M Biselli
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Via Massarenti 9, Italy
    Dig Liver Dis 38:27-32. 2006
    ..AIMS AND PATIENTS: We evaluated the efficacy and safety of pegylated interferon and ribavirin in 20 patients with recurrent Hepatitis C virus after liver transplantation (10 naïve and 10 non-responders to a previous interferon course)...
  13. doi request reprint A novel stop codon mutation within the hepatitis B surface gene is detected in the liver but not in the peripheral blood mononuclear cells of HIV-infected individuals with occult HBV infection
    R Cassini
    Department of Clinical Medicine, University of Bologna, Bologna, Italy
    J Viral Hepat 20:42-9. 2013
    ..HBV-DNA detection in PBMC may offer a useful tool to identify OHB in serum-negative cases. The novel HBs gene stop codon found in LT could be responsible for reduced production leading to undetectability of HBsAg...
  14. ncbi request reprint Vitamin E as treatment for chronic hepatitis B: results of a randomized controlled pilot trial
    P Andreone
    Semeiotica Medica, Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, Universita di Bologna, Policlinico Sant Orsola, Via Massarenti, 9, 40138, Bologna, Italy
    Antiviral Res 49:75-81. 2001
    ..It has been shown that vitamin E can increase the host immune response, and this may provide protection against infectious diseases...
  15. ncbi request reprint Increased generation of reactive oxygen species in isolated rat fatty liver during postischemic reoxygenation
    B Nardo
    Dipartimento di Discipline Chirurgiche, Rianimatorie e dei Trapianti, University of Bologna, Policlinico Sant Orsola, Via Massarenti 9, 40138 Bologna, Italy
    Transplantation 71:1816-20. 2001
    ..Thus, this study aimed to compare the ROS formation that occurs during postanoxic reoxygenation in isolated normal and fatty livers...
  16. ncbi request reprint Virological analysis, genotypes and mutational patterns of the HBV precore/core gene in HBV/HCV-related hepatocellular carcinoma
    M S De Mitri
    Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, Bologna, Italy
    J Viral Hepat 13:574-81. 2006
    ..The mutational pattern of the pre-C/C region was closely related to HBV replication efficiency, and specific HBV mutations selectively associated with HCV co-infection could be linked with accelerated HBV/HCV-related disease progression...
  17. doi request reprint Antagonism of the cannabinoid CB-1 receptor protects rat liver against ischaemia-reperfusion injury complicated by endotoxaemia
    P Caraceni
    Department of Clinical Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy
    Gut 58:1135-43. 2009
    ..Thus, we aimed to determine the effect of the endocannabinoid CB1-receptor antagonist Rimonabant in a model of hepatic IR injury complicated by endotoxaemia...
  18. doi request reprint Liver transplantation for hepatocellular carcinoma: results of down-staging in patients initially outside the Milan selection criteria
    M Ravaioli
    Department of Liver and Multi organ Transplantation, Pathology Division of The F Addarii Institute, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Am J Transplant 8:2547-57. 2008
    ..The actuarial intention-to-treat survival was 27/48 patients (56.3%) in the down-staging and 81/129 cases (62.8%) in the Milan group, p = n.s. The proposed down-staging criteria provide a comparable outcome to the conventional criteria...
  19. pmc Impact of interferon therapy on the natural history of hepatitis C virus related cirrhosis
    A Gramenzi
    Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, , Bologna, Italy
    Gut 48:843-8. 2001
    ..Patients who achieved sustained aminotransferase normalisation survived and did not develop any complications during follow up...
  20. ncbi request reprint Protective effect of portal vein arterialization in acute liver failure induced by hepatectomy in normal and fatty liver rat
    B Nardo
    Department of Surgery and Transplantation, University of Bologna, Bologna, Italy
    Transplant Proc 38:3249-50. 2006
    ..We sought to determine whether an additional supply of oxygenated blood achieved by partial portal vein arterialization (PPVA) was protective on normal or fatty liver (FL) in rats with acute liver failure (ALF) induced by hepatectomy...
  21. ncbi request reprint Immunological modifications during treatment with thymosin alpha1 plus antiviral therapy in chronic hepatitis C
    E Grandini
    Department of Clinical Medicine, University of Bologna, Bologna, Italy
    Ann N Y Acad Sci 1194:147-52. 2010
    ..An accurate selection of HCV patients who can benefit from immunomodulation is needed...
  22. ncbi request reprint Portal vein arterialization for the treatment of post resection acute liver failure in the rat
    B Nardo
    Department of Surgery and Transplantations, S Orsola Malpighi Hospital, University of Bologna, Italy
    Transplant Proc 38:1185-6. 2006
    ..Thus, this study sought to determine whether an additional supply of oxygenated blood delivered by portal vein arterialization (PVA) was protective against acute liver failure induced by hepatectomy...
  23. ncbi request reprint Thymosin-alpha 1 plus interferon-alpha for naive patients with chronic hepatitis C: results of a randomized controlled pilot trial
    P Andreone
    Semeiotica Medica, Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, Università di Bologna Istituto Oncologico, Italy
    J Viral Hepat 11:69-73. 2004
    ..Higher doses and/ore more prolonged courses as well as the association with new interferon formulation such as pegylated interferons could improve the sustained response rates to this treatment...
  24. ncbi request reprint New infection with heterotypic hepatitis C virus in a patient with long-term hepatitis C virus eradication
    M S De Mitri
    Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, Italy
    Dig Liver Dis 33:591-4. 2001
    ..Experimental hepatitis C virus infection in chimpanzees has shown that natural hepatitis C virus infection does not induce protective immunity and reinfection can occur in seroconverted animals...
  25. doi request reprint Serum hepatitis B surface antigen monitoring in long-term lamivudine-treated hepatitis B virus patients
    A Gramenzi
    Department of Clinical Medicine, University of Bologna, Bologna, Italy
    J Viral Hepat 18:e468-74. 2011
    ..If validated prospectively in a larger patient cohort, HBsAg measurements would be a useful adjunct to optimize antiviral therapy...
  26. ncbi request reprint Autonomic dysfunction and hyperdynamic circulation in cirrhosis with ascites
    F Trevisani
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Italy
    Hepatology 30:1387-92. 1999
    ..46; P =.013). Even closer correlations were found with vagal score. AD (mainly VD) may be involved in the pathogenesis of the hyperdynamic circulatory syndrome of patients with advanced cirrhosis...
  27. doi request reprint Alcohol and viral hepatitis: a mini-review
    S Gitto
    Department of Medicine, University of Bologna, Bologna, Italy
    Dig Liver Dis 41:67-70. 2009
    ..Abstinence could reverse some of these deleterious effects...
  28. ncbi request reprint Cytokine profile of peripheral blood mononuclear cells from patients with different outcomes of hepatitis C virus infection
    A Gramenzi
    Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, Universita degli Studi di Bologna, Italy
    J Viral Hepat 12:525-30. 2005
    ....
  29. doi request reprint Allocation priority in non-urgent liver transplantation: An overview of proposed scoring systems
    S Gitto
    Department of Clinical Medicine, University of Bologna, Semeiotica Medica, Sant Orsola Malpighi Hospital, Bologna, Italy
    Dig Liver Dis 41:700-6. 2009
    ..In conclusion, several scoring systems have been described for organ allocation, but today, none is definitely able to overcome the limitations of the Child-Turcotte-Pugh and model for end-stage liver disease systems...
  30. ncbi request reprint Transthoracic electrical bioimpedance: a non-invasive technique for the evaluation of the haemodynamic alterations in patients with liver cirrhosis
    F Dazzani
    Department of Internal Medicine and Hepatology, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy
    Dig Liver Dis 37:786-92. 2005
    ..We, therefore, aimed to compare transthoracic electrical bioimpedance and echocardiography in the assessment of haemodynamic status in cirrhotic patients...
  31. doi request reprint In vitro effect of thymosin-alpha1 and interferon-alpha on Th1 and Th2 cytokine synthesis in patients with eAg-negative chronic hepatitis B
    E Loggi
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Bologna, Italy
    J Viral Hepat 15:442-8. 2008
    ..These results need further investigations, but reinforce the idea of an immunotherapeutic approach for chronic hepatitis B...
  32. ncbi request reprint Predicting the development of hepatocellular cancer in hepatitis B carriers
    M S De Mitri
    Department of Internal Medicine, Cardioangiology, Hepatology Alma Mater Studiorum, University of Bologna, Italy
    Gut 57:12-5. 2008
  33. ncbi request reprint Effects of granulocyte colony stimulating-factor in a rat model of acute liver injury
    P Caraceni
    Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, and Ospedale Policlinico S Orsola Malpighi, Bologna, Italy
    Dig Liver Dis 39:943-51. 2007
    ..We investigated whether different schedules of granulocyte colony stimulating-factor administration protect against experimental acute liver injury...
  34. ncbi request reprint High risk of hepatocellular carcinoma in anti-HBe positive liver cirrhosis patients developing lamivudine resistance
    P Andreone
    Semeiotica Medica, Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, Universita di Bologna, 40138 Bologna, Italy
    J Viral Hepat 11:439-42. 2004
    ..4; 95% CI: 1.3-84.9). Our study suggests that the occurrence of lamivudine resistance increases the risk of hepatocellular carcinoma in anti-HBe positive cirrhosis and warrants further research...
  35. ncbi request reprint Prophylaxis and treatment of hepatis B virus infection after liver transplantation
    P Andreone
    Policlinico S Orsola Malpighi, Via Massarenti, 9 40138 Bologna, Italy
    Transplant Proc 35:1022-4. 2003
  36. ncbi request reprint Effects of the combined treatment with thalidomide, megestrol and interleukine-2 in cirrhotic patients with advanced hepatocellular carcinoma. A pilot study
    F Mirici Cappa
    Department of Internal Medicine Cardioangiology Hepatology, University of Bologna, Via Albertoni 15, 40138 Bologna, Italy
    Dig Liver Dis 37:254-9. 2005
    ..AIMS.: We assessed the effectiveness/safety of a combined therapy with thalidomide+megestrol+interleukin-2 in cirrhotic patients with advanced hepatocellular carcinoma...
  37. ncbi request reprint Review article: alcoholic liver disease--pathophysiological aspects and risk factors
    A Gramenzi
    Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, Universita di Bologna, Policlinico S Orsola, Via Massarenti 9, 40138 Bologna, Italy
    Aliment Pharmacol Ther 24:1151-61. 2006
    ..It is an extremely common disease with significant morbidity and mortality, but the reason why only a relatively small proportion of heavy drinkers progress to advanced disease remains elusive...
  38. ncbi request reprint Oxidative injury in rat fatty liver exposed to ischemia-reperfusion is modulated by nutritional status
    M Domenicali
    Department of Internal Medicine, University of Bologna, Bologna, Italy Center for Applied Biomedical Research C R B A, University of Bologna, Bologna, Italy
    Dig Liver Dis 37:689-97. 2005
    ..Oxidative stress contributes to ischemia-reperfusion injury in fatty livers. This study aimed to determine whether glycogen depletion influences this oxidative injury and whether the administration of glucose can be protective...
  39. ncbi request reprint Posttransplant lymphoproliferative disorders in liver transplanted patients: a report of four cases
    S Lorenzini
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, and Department of Gastroenterology and Internal Medicine, Orsola Malpighi Hospital, Bologna, Italy
    Transplant Proc 38:1477-80. 2006
    ..They are often the result of Epstein-Barr virus (EBV)-induced proliferation of B-lymphocytes in the setting of immunosuppression...
  40. doi request reprint Incidence of craving for and abuse of gamma-hydroxybutyric acid (GHB) in different populations of treated alcoholics: an open comparative study
    F Caputo
    G Fontana Centre for the Study and Multidisciplinary Treatment of Alcohol Addiction, Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Bologna, Italy
    J Psychopharmacol 23:883-90. 2009
    ....
  41. ncbi request reprint Genetic variability of hepatitis C virus in HBV/HCV co-infection and HCV single-infection
    M S De Mitri
    Department of Internal Medicine, Cardioangiology and Hepatology, Policlinico S Orsola Malpighi, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Arch Virol 150:261-71. 2005
    ..Furthermore, in the cases of HCV dominance, circulating HBV genomes did not have a significant effect on the viral heterogeneity of HCV...
  42. doi request reprint Stem cell mobilization and collection in patients with liver cirrhosis
    S Lorenzini
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Bologna, Italy
    Aliment Pharmacol Ther 27:932-9. 2008
    ..Bone marrow-derived stem cells (BMSC) and granulocyte colony-stimulating factor (G-CSF) have been proved to contribute to tissue regeneration after liver injury...
  43. doi request reprint The endocannabinoid system and liver diseases
    P Caraceni
    Department of Internal Medicine, Cardioangiology, Hepatology, Alma Mater Studiorum University of Bologna, Bologna, Italy
    J Neuroendocrinol 20:47-52. 2008
    ....
  44. ncbi request reprint Malignant progression of a small HCC nodule: hypovascular 'early HCC' converted to hypervascular 'small HCC' within six months
    R Golfieri
    Department of Radiology, Sant Orsola Malpighi Hospital, University of Bologna, Italy
    Dig Liver Dis 39:883-90. 2007
    ....
  45. doi request reprint "Torsade de pointes" during amiodarone infusion in a cirrhotic woman with a prolonged QT interval
    A Di Micoli
    Department of Internal Medicine, Cardioangiology and Hepatololgy Alma Mater Studiorum, University of Bologna, Bologna, Italy
    Dig Liver Dis 41:535-8. 2009
    ..Moreover, beta-blockers may be considered the first-line treatment for rate-control during supraventricular tachyarrhythmias in cirrhotic patients with delayed repolarization...
  46. ncbi request reprint Mars and Prometheus: our clinical experience in acute chronic liver failure
    S Faenza
    Department of Surgery, Intensive Care and Transplantation, Policlinico Sant Orsola, Bologna, Italy
    Transplant Proc 40:1169-71. 2008
    ..In our clinical context, there are two groups that practice blood purification treatments on acute or chronic liver failure (AoCLF) patients: one group used MARS (molecular adsorbent recirculating system) and the other Prometheus...
  47. ncbi request reprint Terlipressin infusion induces ischemia of breast skin in a cirrothic patient with hepatorenal syndrome
    A Di Micoli
    Department of Internal Medicine, Cardioangiology and Hepatology, Alma Mater Studiorum, University of Bologna, Bologna, Italy
    Dig Liver Dis 40:304-5. 2008
    ..Probably, this particular behaviour could be explained by the anatomical position of her large size breasts, that resulting as an extremely sloping and stretching region thus filling the maximum effect of gravity...
  48. ncbi request reprint Efficacy and safety of the stepped care medical treatment of ascites in liver cirrhosis: a randomized controlled clinical trial comparing two diets with different sodium content
    M Bernardi
    Cattedra di Patologia Speciale Medica I, University of Bologna, Italy
    Liver 13:156-62. 1993
    ..Multivariate analysis showed that creatinine clearance and plasma aldosterone were independent predictive factors of the response to treatment.(ABSTRACT TRUNCATED AT 250 WORDS)..
  49. ncbi request reprint Randomized control trials on chemoembolization for hepatocellular carcinoma: is there room for new studies?
    F Trevisani
    Dipartimento di Medicina Interna, Cardioangiologia, Epatologia, Universita di Bologna, Bologna, Italy
    J Clin Gastroenterol 32:383-9. 2001
    ..It seems more realistic to expect randomized studies comparing different techniques and time schedules of treatment, as well as TACE alone versus combined procedures...
  50. ncbi request reprint Doxorubicin coupled to lactosaminated albumin: Effects on rats with liver fibrosis and cirrhosis
    G Di Stefano
    Department of Experimental Pathology, University of Bologna, Via San Giacomo 14, 40126 Bologna, Italy
    Dig Liver Dis 38:404-8. 2006
    ..However, coupled doxorubicin also accumulates in the liver, which might damage hepatocytes...
  51. doi request reprint Recent advances in the natural history of hepatocellular carcinoma
    F Trevisani
    Dipartimento di Medicina Clinica, Universita di Bologna, Via Albertoni 15, 40138 Bologna, Italy
    Carcinogenesis 29:1299-305. 2008
    ..By addressing 10 key questions, this review will summarize well-established and novel features of the natural history of HCC...
  52. ncbi request reprint Serum alpha-fetoprotein for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: influence of HBsAg and anti-HCV status
    F Trevisani
    Dipartimento di Medicina Interna, Cardioangiologia, Epatologia, University of Bologna, Italy
    J Hepatol 34:570-5. 2001
    ..It is not established whether virological status affects the efficiency of alpha-fetoprotein (AFP) as a hepatocellular carcinoma (HCC) marker among patients with chronic liver disease (CLD)...
  53. ncbi request reprint Interferon alpha plus ketoprofen or interferon alpha plus ribavirin in chronic hepatitis C non-responder to interferon alpha alone: results of a pilot study
    P Andreone
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Italy
    Ital J Gastroenterol Hepatol 31:688-94. 1999
    ..Recently, in vitro and in vivo studies demonstrated that non-steroidal anti-inflammatory drugs are able to enhance the activity of interferon alpha...
  54. ncbi request reprint Interferon-alpha plus ribavirin and amantadine in patients with post-transplant hepatitis C: results of a pilot study
    P Andreone
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Italy
    Dig Liver Dis 33:693-7. 2001
    ..Recurrence of hepatitis C after liver transplantation is almost constant and may lead to graft loss. The results of treatment with interferon and/or other agents have been controversial...
  55. ncbi request reprint Prevalence of monoclonal gammopathies in patients with hepatitis C virus infection
    P Andreone
    Università di Bologna and Policlinico S Orsola, Italy
    Ann Intern Med 129:294-8. 1998
    ..An association between monoclonal gammopathies and chronic liver diseases has been reported...
  56. doi request reprint A fast and validated mass spectrometry method for the evaluation of human serum albumin structural modifications in the clinical field
    M Naldi
    Centro Interdipartimentale di Ricerche Biotecnologiche, Bologna, Italy
    Eur J Mass Spectrom (Chichester, Eng) 19:491-6. 2013
    ....
  57. ncbi request reprint Evidence of oxidative imbalance in long-term liver transplant patients
    F Trevisani
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Italy
    Dig Liver Dis 34:279-84. 2002
    ..Previous studies have provided information limited to the immediate post-operative period. It remains to be established whether this oxidative imbalance is reversed in a longer time...
  58. ncbi request reprint Adaptive response in hepatitis B virus infection
    E Loggi
    Institute for Research in Biomedicine, Bellinzona, Switzerland Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
    J Viral Hepat 21:305-13. 2014
    ..In addition to CD8+ T cells, which are the best-described subset to date, we reviewed and commented on the direct and indirect roles of CD4+ T cells and B cells. ..
  59. ncbi request reprint Portal vein arterialization: a new surgical option against acute liver failure?
    B Nardo
    Department of Surgery, Intensive Care Unit and Transplantation, University of Bologna, Bologna, Italy
    Transplant Proc 37:2544-6. 2005
    ..We believe that this novel approach, which should promote liver regeneration by providing an additional oxygen supply to the liver, may disclose a new possibility in the treatment of ALF and prompt new clinical and experimental research...
  60. ncbi request reprint Soluble CD30 serum level in HCV-positive chronic active hepatitis: A surrogate marker of disease activity?
    F G Foschi
    Semeiotica Medica, Dipartimento di Medicina Interna, Cardioangiologia, Epatologia, Universita di Bologna, Bologna, Italy
    Cytokine 12:815-8. 2000
    ..5; P=0.006). The raised CD30s level found in more severe HCV liver disease indirectly suggests activation and expansion of Th(2)cells. CD30s levels could represent a useful surrogate marker of activity in chronic HCV infections...
  61. pmc Impaired tuftsin activity in cirrhosis: relationship with splenic function and clinical outcome
    F Trevisani
    Semeiotica Medica, Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, University of Bologna, Italy
    Gut 50:707-12. 2002
    ....
  62. ncbi request reprint Gamma-hydroxybutyric acid versus naltrexone in maintaining alcohol abstinence: an open randomized comparative study
    F Caputo
    Department of Internal Medicine, Cardioangiology and Hepatology, G Fontana Centre for the Study and Treatment of Alcohol Addiction, University of Bologna, Via Massarenti no 9, Bologna, 40138, Italy
    Drug Alcohol Depend 70:85-91. 2003
    ..The results of the present study show that GHB is more effective than NTX in maintaining abstinence from alcohol in a short-term treatment period; on the other hand, NTX confirmed its ability to reduce alcohol relapses...
  63. ncbi request reprint Interferon-alpha combined with ketoprofen as treatment of naïve patients with chronic hepatitis C: a randomized controlled trial
    P Andreone
    Semeiotica Medica, Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, Universita di Bologna, Italy
    J Viral Hepat 10:306-9. 2003
    ..Thus, the role of ketoprofen in the treatment of chronic hepatitis C needs to be further evaluated against such a treatment...
  64. ncbi request reprint Short-term methadone administration reduces alcohol consumption in non-alcoholic heroin addicts
    F Caputo
    G Fontana Centre for the Study and Treatment of Alcohol Addiction, Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Via Massarenti n 9th, 40138 Bologna, Italy
    Alcohol Alcohol 37:164-8. 2002
    ..The results of the present study suggest a possible effect of short-term methadone administration in reducing alcohol consumption in a population of non-alcoholic heroin-addicted patients...
  65. ncbi request reprint Mutations in the E2-PePHD region of hepatitis C virus type 1b in patients with hepatocellular carcinoma
    S Bagaglio
    Department of Infectious Diseases, San Raffaele, Scientific Institute, 20127 Milan, Italy
    J Viral Hepat 12:243-50. 2005
    ..The analysis of 461 sequences obtained from GenBank supports the conclusion that the observed aa change is an infrequent event in HCV-infected patients, thus suggesting that it could be associated with HCC...
  66. ncbi request reprint Human herpesvirus-8-related Kaposi's sarcoma after liver transplantation successfully treated with cidofovir and liposomal daunorubicin
    G Verucchi
    Department of Clinical and Experimental Medicine, Section of Infectious Diseases, S Orsola Hospital Alma Mater Studiorum University of Bologna, Italy
    Transpl Infect Dis 7:34-7. 2005
    ....
  67. pmc High incidence of allograft dysfunction in liver transplanted patients treated with pegylated-interferon alpha-2b and ribavirin for hepatitis C recurrence: possible de novo autoimmune hepatitis?
    S Berardi
    Dipartimento di Medicina Interna et Gastroenterologia, Universita di Bologna, Italy
    Gut 56:237-42. 2007
    ..Interferon may trigger autoimmune disorders, including autoimmune hepatitis, in immunocompetent patients. To date, no such disorders have been described in liver transplanted patients...
  68. ncbi request reprint Adaptation of subcellular glutathione detoxification system to stress conditions in choline-deficient diet induced rat fatty liver
    I Grattagliano
    Section of Internal Medicine, Department of Internal Medicine and Public Medicine, University Medical School of Bari, Italy
    Cell Biol Toxicol 19:355-66. 2003
    ..Differences emerge among subcellular compartments which point to differential adaptation of these organelles to fatty degeneration...
  69. ncbi request reprint Molecular characterization and sequence analysis of polyomavirus BKV-strain in a renal-allograft recipient
    R Boldorini
    , , Novara, Italy
    Hum Pathol 32:656-9. 2001
    ..These data suggest that only the BKV, probably favoured by immunosuppressive therapy (tacrolimus), causes renal damage. It is worth underlining that even small and sporadic viral genome mutations may lead to pathologic effects...
  70. ncbi request reprint Experimental observations and clinical implications of fasting and diet supplementation in fatty livers
    I Grattagliano
    Section of Internal Medicine, Department of Internal Medicine and Public Medicine, University Medical School, Bari, Italy
    Eur Rev Med Pharmacol Sci 7:1-7. 2003
    ....
  71. ncbi request reprint Mitochondrial oxidative injury and energy metabolism alteration in rat fatty liver: effect of the nutritional status
    G Vendemiale
    Department of Internal and Public Medicine (DIMIMP, University of Bari, Italy
    Hepatology 33:808-15. 2001
    ..These changes, which are greatly exacerbated after starvation, may account for the reduced synthesis of the hepatic ATP observed in the presence of fatty infiltration...
  72. ncbi request reprint Rapamycin induces a caspase-independent cell death in human monocytes
    A Mercalli
    Immunology of Diabetes Unit, San Raffaelle Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    Am J Transplant 6:1331-41. 2006
    ....
  73. ncbi request reprint Focal nodular hyperplasia after busulfan treatment
    F G Foschi
    Department of Internal Medicine, Faenza Hospital, Via Stradone no 9, 48018 Faenza RA, Italy
    Dig Liver Dis 37:619-21. 2005
    ..The close temporal relation between the haematological disease, busulfan treatment and the appearance of hyperplastic diseases of the liver in our patient supports the possibility that the association of the events might not be casual...
  74. ncbi request reprint The rational use of albumin in patients with cirrhosis and ascites. A Delphi study for the attainment of a consensus on prescribing standards
    P Gentilini
    Department of Internal Medicine, University of Florence, Vale Morgagni 85, 50134 Florence, Italy
    Dig Liver Dis 36:539-46. 2004
    ..The treatment of this chronic disease usually requires the prolonged use of albumin, frequently continued even after patients' discharge from the hospital...
  75. ncbi request reprint Intranasal mupirocin reduces sternal wound infection after open heart surgery in diabetics and nondiabetics
    G E Cimochowski
    Department of Cardiac Surgery, Wilkes-Barre General Hospital, Pennsylvania, USA
    Ann Thorac Surg 71:1572-8; discussion 1578-9. 2001
    ..CONCLUSIONS: Prophylactic intranasal MPN is safe, inexpensive, and very effective in reducing the overall sternal wound infections by 66.6%...
  76. ncbi request reprint Factor VIII and von Willebrand factor changes after desmopressin and during pregnancy in type 2M von Willebrand disease Vicenza: a prospective study comparing patients with single (R1205H) and double (R1205H-M740I) defect
    G Castaman
    Department of Hematology and Hemophilia and Thrombosis Center, San Bortolo Hospital, Vicenza, Italy
    J Thromb Haemost 4:357-60. 2006
    ..No data on FVIII/VWF changes after desmopressin and during pregnancy in patients with phenotypic VWD Vicenza has been reported...
  77. pmc Sepsis in cirrhosis: report on the 7th meeting of the International Ascites Club
    F Wong
    Division of Gastoenterology, Toronto General Hospital, University of Toronto, Ontario, Canada
    Gut 54:718-25. 2005
    ..The use of antibiotics has to be judicious, as their indiscriminate use can lead to antibiotic resistance with potentially disastrous consequences...