F Benazzi

Summary

Affiliation: University of Bologna
Country: Italy

Publications

  1. doi request reprint Defining mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 32:932-9. 2008
  2. ncbi request reprint Major depressive disorder with anger: a bipolar spectrum disorder?
    Franco Benazzi
    Outpatient Psychiatry Center, University of California, San Diego, Calif, USA
    Psychother Psychosom 72:300-6. 2003
  3. ncbi request reprint Testing DSM-IV definition of atypical depression
    Franco Benazzi
    Outpatient Psychiatry Center, University of California at San Diego, USA
    Ann Clin Psychiatry 15:9-16. 2003
  4. ncbi request reprint Agitated depression: a valid depression subtype?
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 28:1279-85. 2004
  5. ncbi request reprint Outcome of schizophreniform disorder
    Franco Benazzi
    Department of Psychiatry, National Health Service, Via Pozzetto 17, 48015 Castiglione di Cervia RA, Italy
    Curr Psychiatry Rep 5:192-6. 2003
  6. ncbi request reprint Family history validation of a definition of mixed depression
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Compr Psychiatry 46:159-66. 2005
  7. ncbi request reprint Depressive mixed state: dimensional versus categorical definitions
    Franco Benazzi
    Outpatient Psychiatry Center, Via Pozzetto 17, 48015 Castiglione di Cervia RA, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 27:129-34. 2003
  8. ncbi request reprint Biphasic course in bipolar II outpatients: prevalence and clinical correlates of a cyclic pattern described by Baillarger and Falret in hospitalised patients in 1854
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Via Pozzetto 17, 48010 Castiglione di Cervia, Ravenna, Italy
    J Affect Disord 96:183-7. 2006
  9. ncbi request reprint The dual factor structure of self-rated MDQ hypomania: energized-activity versus irritable-thought racing
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 73:59-64. 2003
  10. ncbi request reprint Refining the evaluation of bipolar II: beyond the strict SCID-CV guidelines for hypomania
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 73:33-8. 2003

Detail Information

Publications115 found, 100 shown here

  1. doi request reprint Defining mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 32:932-9. 2008
    ..However, it is still unclear if its definition should be based on specific manic symptoms or on a number/score of manic symptoms. Different definitions may have different diagnostic utility, such as treatment impacts...
  2. ncbi request reprint Major depressive disorder with anger: a bipolar spectrum disorder?
    Franco Benazzi
    Outpatient Psychiatry Center, University of California, San Diego, Calif, USA
    Psychother Psychosom 72:300-6. 2003
    ..The aim of the study was to assess whether major depressive disorder (MDD) with anger could be included in the bipolar spectrum, by comparing it to MDD without anger and to bipolar II disorder...
  3. ncbi request reprint Testing DSM-IV definition of atypical depression
    Franco Benazzi
    Outpatient Psychiatry Center, University of California at San Diego, USA
    Ann Clin Psychiatry 15:9-16. 2003
    ..All AD symptoms were significantly associated with DSM-IV AD, and with most study variables. Results support the current DSM-IV definition of AD...
  4. ncbi request reprint Agitated depression: a valid depression subtype?
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 28:1279-85. 2004
    ..It is not classified in DSM-IV and ICD-10 classification of mental and behavioural disorder (ICD-10). Some data support its subtyping. This study aims to test the subtyping of AD...
  5. ncbi request reprint Outcome of schizophreniform disorder
    Franco Benazzi
    Department of Psychiatry, National Health Service, Via Pozzetto 17, 48015 Castiglione di Cervia RA, Italy
    Curr Psychiatry Rep 5:192-6. 2003
    ..If confirmed by future studies, these preliminary findings can have very important treatment implications, given the very different treatment strategies in mood disorders compared with schizophrenia...
  6. ncbi request reprint Family history validation of a definition of mixed depression
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Compr Psychiatry 46:159-66. 2005
    ..The study aim was to test different definitions of mixed depression, defined as a depression with concurrent hypomanic symptoms...
  7. ncbi request reprint Depressive mixed state: dimensional versus categorical definitions
    Franco Benazzi
    Outpatient Psychiatry Center, Via Pozzetto 17, 48015 Castiglione di Cervia RA, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 27:129-34. 2003
    ..It is still unclear how to best define DMX. The study's aim was to test a categorical versus a dimensional definition of DMX...
  8. ncbi request reprint Biphasic course in bipolar II outpatients: prevalence and clinical correlates of a cyclic pattern described by Baillarger and Falret in hospitalised patients in 1854
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Via Pozzetto 17, 48010 Castiglione di Cervia, Ravenna, Italy
    J Affect Disord 96:183-7. 2006
    ..These patients would probably have today met the criteria for bipolar I. Our aim was to find the prevalence and clinical correlates of biphasic course in bipolar II (BP II) in contemporary ambulatory patients...
  9. ncbi request reprint The dual factor structure of self-rated MDQ hypomania: energized-activity versus irritable-thought racing
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 73:59-64. 2003
    ..Bipolar II is diagnosed in a clinically depressed patient by documenting history of hypomania. Therefore, it is of great significance for both clinical and research purposes to characterize the factor structure of hypomania...
  10. ncbi request reprint Refining the evaluation of bipolar II: beyond the strict SCID-CV guidelines for hypomania
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 73:33-8. 2003
    ..Our objective was to further refine the strict SCID-CV guidelines for hypomania in depressed outpatients...
  11. ncbi request reprint Which could be a clinically useful definition of depressive mixed state?
    Franco Benazzi
    Outpatient Psychiatry Center, University of California in San Diego USA Collaborating Center, San Diego, CA, USA
    Prog Neuropsychopharmacol Biol Psychiatry 26:1105-11. 2002
    ..Study aim was to find if the best clinically useful definition of DMX was one based on a minimum number of hypomanic symptoms, or instead one based on the combination of specific hypomanic symptoms...
  12. ncbi request reprint The duration of hypomania in bipolar-II disorder in private practice: methodology and validation
    Franco Benazzi
    Outpatient Psychiatry Center, Ravenna, Italy
    J Affect Disord 96:189-96. 2006
    ..Epidemiologic data suggest that briefer hypomanias are prevalent in the community. We sought to find out the relative prevalence of short (2-3 days) versus long (>/=4 days) hypomanias in private practice...
  13. ncbi request reprint Depressive mixed state frequency: age/gender effects
    Franco Benazzi
    The Outpatient Psychiatry Private Center, A University of California in San Diego Collaborating Center, Ravenna and Forli, Italy
    Psychiatry Clin Neurosci 56:537-43. 2002
    ..A bipolar vulnerability seems to be required for the appearance of DMX3 also in later life...
  14. ncbi request reprint Should mood reactivity be included in the DSM-IV atypical features specifier?
    Franco Benazzi
    Eur Arch Psychiatry Clin Neurosci 252:135-40. 2002
    ..The study aim was to test whether mood reactivity should be included in DSM-IV atypical features specifier...
  15. ncbi request reprint Delineating bipolar II mixed states in the Ravenna-San Diego collaborative study: the relative prevalence and diagnostic significance of hypomanic features during major depressive episodes
    F Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 67:115-22. 2001
    ....
  16. ncbi request reprint Depressive mixed state: testing different definitions
    F Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Psychiatry Clin Neurosci 55:647-52. 2001
    ..Findings have important clinical and treatment implications because antidepressants may worsen DMX, and the presence of DMX may induce clinicians to assess systematically and carefully the history of past hypomania...
  17. ncbi request reprint Age at onset of bipolar II depressive mixed state
    F Benazzi
    Department of Psychiatry, National Health Service A USL, P Solieri 4, 47100, Forli, Italy
    Psychiatry Res 103:229-35. 2001
    ..DMS2 was more likely in bipolar II with a younger age at onset. Different bipolar II ages at onset did not have an effect on DMS2 clinical correlates...
  18. ncbi request reprint Clinical differences between bipolar II depression and unipolar major depressive disorder: lack of an effect of age
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 75:191-5. 2003
    ..Age difference may be a confounding factor. Study aims were to describe the clinical and family history features of bipolar II versus unipolar depression, and to control for the possible confounding effect of age on clinical features...
  19. ncbi request reprint Frequency of bipolar spectrum in 111 private practice depression outpatients
    F Benazzi
    Via Pozzetto 17, 48010 Castiglione di Cervia RA, Italy
    Eur Arch Psychiatry Clin Neurosci 253:203-8. 2003
    ..Mood disorders included into the bipolar spectrum are increasing, and overactivity (increased goal-directed activity) has reached the status of mood change for the diagnosis of hypomania in the recent studies by Angst and Akiskal...
  20. ncbi request reprint A downscaled practical measure of mood lability as a screening tool for bipolar II
    Franco Benazzi
    Outpatient Psychiatry Center Ravenna and Forli, Italy and the Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 84:225-32. 2005
    ..Accordingly, the aim of the present analyses was to test if a practical measure of mood lability was unique to BPII, in comparison with major depressive disorder (MDD)...
  21. ncbi request reprint Factor structure of recalled DSM-IV hypomanic symptoms of bipolar II disorder
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Compr Psychiatry 45:441-6. 2004
    ....
  22. ncbi request reprint Inter-episode mood lability in mood disorders: residual symptom or natural course of illness?
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna and the Department of Psychiatry, National Health Service, Forli, Italy
    Psychiatry Clin Neurosci 58:480-6. 2004
    ....
  23. ncbi request reprint Depressive mixed state: a feature of the natural course of bipolar II (and major depressive) disorder?
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Psychopathology 37:207-12. 2004
    ..Kraepelin observed, in an inpatient sample, that DMX was related to the number of episodes and to duration of manic-depressive insanity (illness)...
  24. ncbi request reprint Mixed states in bipolar II disorder: should full hypomania always be required?
    Franco Benazzi
    University of California at San Diego USA Collaborating Center, USA
    Psychiatry Res 127:247-57. 2004
    ..The high frequency of DMX in bipolar II MDE supports the need for controlled studies to test the effects of antidepressants on depressive mixed state (as clinical observations suggest possible negative effects)...
  25. ncbi request reprint Intra-episode hypomanic symptoms during major depression and their correlates
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Psychiatry Clin Neurosci 58:289-94. 2004
    ..Predicting the switch might have important treatment implications, because antidepressants used alone may worsen the course of bipolar disorders. Prospective studies are required to support these findings and hypotheses...
  26. ncbi request reprint Is depressive mixed state a transition between depression and hypomania?
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Eur Arch Psychiatry Clin Neurosci 254:69-75. 2004
    ..Study aim was to find if DMX in bipolar II disorder was often a transition period between depression and hypomania, as suggested by Kraepelin...
  27. ncbi request reprint Melancholic outpatient depression in Bipolar-II vs. unipolar
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 28:481-5. 2004
    ..DSM-IV melancholic major depressive episode (MDE) in bipolar II disorder (BP-II) is understudied. Study aim was to compare melancholic MDE in BP-II vs. unipolar major depressive disorder (MDD) on diagnostic validators and clinical features...
  28. ncbi request reprint Toward a validation of a new definition of agitated depression as a bipolar mixed state (mixed depression)
    F Benazzi
    Centro Lucio Bini, outpatient private practice, Rome, Italy
    Eur Psychiatry 19:85-90. 2004
    ....
  29. ncbi request reprint Validating Angst's "ups & downs" personality trait as a new marker of bipolar II disorder
    Franco Benazzi
    Via Pozzetto 17, 48010 Castiglione di Cervia RA, Italy
    Eur Arch Psychiatry Clin Neurosci 254:48-54. 2004
    ..Study aim was to find the frequency of "ups & downs" in a large sample of bipolar II (BPII) and major depressive disorder (MDD),and to test its association with BPII...
  30. ncbi request reprint Bipolar II disorder and major depressive disorder: continuity or discontinuity?
    Franco Benazzi
    Outpatient Psychiatrist Private Centre, Ravenna and Forli, Italy
    World J Biol Psychiatry 4:166-71. 2003
    ..To find if bipolar II disorder (BPII) and major depressive disorder (MDD) were distinct categories or overlapping syndromes...
  31. ncbi request reprint Depression with racing thoughts
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Psychiatry Res 120:273-82. 2003
    ..Depression with racing thoughts was very common in depressed outpatients, and was associated with suicidal ideation. Possible differential effects of antidepressants vs. mood stabilizers and antipsychotics are discussed...
  32. ncbi request reprint The role of gender in depressive mixed state
    Franco Benazzi
    Outpatient Psychiatry Center, Ravenna and Forli, Italy
    Psychopathology 36:213-7. 2003
    ..Study aims were to find the prevalence of women, and to study gender differences in depressive mixed state (DMX), a major depressive episode (MDE) with few concurrent hypomanic symptoms...
  33. ncbi request reprint Diagnosis of bipolar II disorder: a comparison of structured versus semistructured interviews
    Franco Benazzi
    Forli University of California at San Diego USA Collaborating Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 27:985-91. 2003
    ..The aim of the study was to find the degree of agreement in the diagnosis of BPII between the Structured Clinical Interview for DSM-IV (SCID) and a semistructured interview based on DSM-IV criteria done by an expert clinician...
  34. ncbi request reprint Factor analysis of the Montgomery Asberg Depression Rating Scale in 251 bipolar II and 306 unipolar depressed outpatients
    F Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 25:1369-76. 2001
    ..Different factor structure (between bipolar II and unipolar depression) supports previous findings that response to antidepressants and biology may be different in bipolar II and unipolar depression...
  35. ncbi request reprint Late-life chronic depression: a 399-case study in private practice
    F Benazzi
    Department of Psychiatry, National Health Service, Public Hospital Morgagni, Forli, Italy
    Int J Geriatr Psychiatry 15:1-6. 2000
    ..A major feature of the study was the inclusion of a large number of bipolar II patients, usually not included in previous studies...
  36. ncbi request reprint Sensitivity and specificity of DSM-IV atypical features for bipolar II disorder diagnosis
    F Benazzi
    Department of Psychiatry, National Institute for Psychiatry and Neurology, Budapest, Hungary
    Psychiatry Res 93:257-62. 2000
    ..As the diagnosis of past hypomania may not be very reliable from a patient's interview, atypical features may be an important marker of bipolar II disorder...
  37. ncbi request reprint Depression with DSM-IV atypical features: a marker for bipolar II disorder
    F Benazzi
    Eur Arch Psychiatry Clin Neurosci 250:53-5. 2000
    ..4% vs 25.4%, odds ratio 2.4). As the diagnosis of bipolar II disorder is often based on diagnosis of past hypomania, which may not be very reliable. depression with atypical features may point to bipolar II disorder diagnosis...
  38. pmc Early- versus late-onset bipolar II disorder
    F Benazzi
    Department of Psychiatry, Morgagni Public Hospital, Forli, Italy
    J Psychiatry Neurosci 25:53-7. 2000
    ..To compare the clinical features and the outcome between patients with early- and late-onset bipolar II disorder...
  39. ncbi request reprint Atypical bipolar II depression compared with atypical unipolar depression and nonatypical bipolar II depression
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni Forlì, Italy
    Psychopathology 33:100-2. 2000
    ..As different ages at onset may identify distinct subtypes of depression, this finding might suggest that atypical bipolar II depression may be distinct from both atypical unipolar depression and nonatypical bipolar II depression...
  40. ncbi request reprint Chronic depression subtypes: a 257 case study
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Depress Anxiety 10:81-4. 1999
    ..Chronic depression subtypes had significantly longer duration of illness, less comorbidity, and more recurrences than nonchronic depression. These findings do not support the DSM-IV subtyping of chronic depression...
  41. ncbi request reprint Psychotic late-life depression: a 376-case study
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Int Psychogeriatr 11:325-32. 1999
    ..Findings were related to psychosis or to age, and not to specific features of psychotic late-life depression. These results support a unitary view of psychotic depression...
  42. ncbi request reprint Bipolar versus unipolar psychotic outpatient depression
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    J Affect Disord 55:63-6. 1999
    ..The relationship between bipolar and unipolar psychotic depression has not been well studied. Therefore, the aim of the present study was to compare bipolar with unipolar psychotic outpatient depression...
  43. ncbi request reprint Prevalence and clinical features of atypical depression in depressed outpatients: a 467-case study
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Psychiatry Res 86:259-65. 1999
    ..Findings suggest that there are important clinical differences between atypical and non-atypical depression in private practice outpatients...
  44. ncbi request reprint A comparison of the age of onset of bipolar I and bipolar II outpatients
    F Benazzi
    J Affect Disord 54:249-53. 1999
    ..Aim of the study was to compare age at onset and indicators of severity (recurrences, chronicity, psychosis) between bipolar I and bipolar II disorders to clarify this point...
  45. ncbi request reprint The Montgomery Asberg Depression Rating Scale in bipolar II and unipolar out-patients: a 405-patient case study
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Psychiatry Clin Neurosci 53:429-31. 1999
    ..Comparisons among atypical and non-atypical bipolar II and unipolar patients showed that only MADRS items of 'reduced sleep' and 'reduced appetite' were significantly different between atypical and non-atypical patients...
  46. ncbi request reprint Gender differences in bipolar II and unipolar depressed outpatients: a 557-case study
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Ann Clin Psychiatry 11:55-9. 1999
    ..Age at onset was significantly lower in bipolar II females than in unipolar females. This difference was not related to the higher prevalence of atypical features in bipolar II females...
  47. ncbi request reprint Prevalence of bipolar II disorder in atypical depression
    F Benazzi
    Eur Arch Psychiatry Clin Neurosci 249:62-5. 1999
    ..The prevalence of bipolar II disorder among atypical depressed outpatients was higher than previously reported...
  48. pmc Is atypical depression a moderate severity depression? A 536-case study
    F Benazzi
    Department of Psychiatry, Morgagni Public Hospital, Forli, Italy
    J Psychiatry Neurosci 24:244-7. 1999
    ..To determine if atypical depression is less common among outpatients with severe depression than among those with nonsevere depression...
  49. ncbi request reprint Weight gain in depression remitted with antidepressants: pharmacological or recovery effect?
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Psychother Psychosom 67:271-4. 1998
    ..It is not clear if weight gain is caused by a pharmacological effect of antidepressants, or if instead it is an effect of recovery from depression. The aim of this study was to try to clarify this point...
  50. pmc Chronic depression: a case series of 203 outpatients treated at a private practice
    F Benazzi
    Department of Psychiatry, Morgagni Public Hospital, Forli, Italy
    J Psychiatry Neurosci 23:51-5. 1998
    ..To determine the prevalence of chronic depression among outpatients seen for depression...
  51. ncbi request reprint Antidepressant-associated hypomania in outpatient depression: a 203-case study in private practice
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    J Affect Disord 46:73-7. 1997
    ..Both unipolar and bipolar switchers had instead early age at onset and frequent atypical features, suggesting that these factors might increase the risk of switching in unipolar depression...
  52. ncbi request reprint Late-life atypical major depressive episode: a 358-case study in outpatients
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Am J Geriatr Psychiatry 8:117-22. 2000
    ....
  53. ncbi request reprint Course and outcome of bipolar II disorder: a retrospective study
    F Benazzi
    Department of Psychiatry, National Health Service, AUSL, Forli, Italy
    Psychiatry Clin Neurosci 55:67-70. 2001
    ..Results support subtyping of Bipolar II in a small good-outcome group, and a large moderate-poor-outcome group...
  54. ncbi request reprint Early-onset versus late-onset atypical depression: unipolar and bipolar II
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, National Health Service, 47100, Forli, Italy
    J Affect Disord 61:95-9. 2000
    ..To find differences between early- and late-onset atypical depression (AD)...
  55. ncbi request reprint Characteristics of bipolar II patients with interpersonal rejection sensitivity
    F Benazzi
    Department of Psychiatry, National Health Service A USL, Forli, Italy
    Psychiatry Clin Neurosci 54:499-501. 2000
    ....
  56. ncbi request reprint Female depression before and after menopause
    F Benazzi
    Department of Psychiatry, National Health Service A USL, Forli, Italy
    Psychother Psychosom 69:280-3. 2000
    ..Aim of the study was to compare female depression with onset before menopause with female depression with onset after menopause, to find out if endocrinological changes had an impact on depression...
  57. ncbi request reprint Exploring aspects of DSM-IV interpersonal sensitivity in bipolar II
    F Benazzi
    Department of Psychiatry, National Health Service AUSL, P Solieri 4, 47100 Forli, Italy
    J Affect Disord 60:43-6. 2000
    ..The aim of the study was to find the prevalence of interpersonal rejection sensitivity (IRS) (a personality trait in DSM-IV) in bipolar II and unipolar depression...
  58. ncbi request reprint The clinical picture of bipolar II outpatient depression in private practice
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, National Health Service, Forli, Italy
    Psychopathology 34:81-4. 2001
    ..The presence of DSM-IV atypical features predicted bipolar II diagnosis with 63% probability...
  59. ncbi request reprint Female vs. male outpatient depression: a 448-case study in private practice
    F Benazzi
    Department of Psychiatry, National Health Service AUSL, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 24:475-81. 2000
    ..3. Private practice outpatient female depression (chronic, psychotic, or recurrent) was not more severe than male depression...
  60. ncbi request reprint Is 4 days the minimum duration of hypomania in bipolar II disorder?
    F Benazzi
    Eur Arch Psychiatry Clin Neurosci 251:32-4. 2001
    ..Bipolar II had significantly lower age at onset, more recurrences, and more atypical features. Findings suggest that hypomania lasting 2 to 3 days may identify a bipolar II group having typical features of bipolar disorders...
  61. ncbi request reprint Atypical depression with hypomanic symptoms
    F Benazzi
    Department of Psychiatry, National Health Service A USL, P Solieri 4, 47100 Forli, Italy
    J Affect Disord 65:179-83. 2001
    ..The aims of this study were to find the prevalence and clinical features of DMS in atypical depression...
  62. ncbi request reprint Prevalence and clinical correlates of residual depressive symptoms in bipolar II disorder
    F Benazzi
    Department of Psychiatry, National Health Service AUSL, Forli, Italy
    Psychother Psychosom 70:232-8. 2001
    ..The study aims were to assess the prevalence and clinical correlates of persistent residual depressive symptoms in bipolar II disorder...
  63. ncbi request reprint Agitated depression: unipolar? Bipolar? Or both?
    Franco Benazzi
    Outpatient Psychiatry Center, University of California, San Diego, USA
    Ann Clin Psychiatry 14:97-104. 2002
    ..Further studies on this topic are needed...
  64. ncbi request reprint Early-onset versus late-onset bipolar II chronic depression
    F Benazzi
    Department of Psychiatry, National Health Service A USL, Foril, Italy
    Depress Anxiety 13:45-9. 2001
    ..Results support the subtyping of bipolar II chronic depression in EO and LO on the basis of different clinical features...
  65. ncbi request reprint Testing atypical depression definitions
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Int J Methods Psychiatr Res 14:82-91. 2005
    ..Pharmacological studies are required to support any new definition of AD, as the current concept of AD is based on different response to TCA antidepressants versus non-AD...
  66. ncbi request reprint Unipolar depression with racing thoughts: a bipolar spectrum disorder?
    Franco Benazzi
    University of California at San Diego, USA, and Hecker Psychiatry Research Center, Ravenna, Italy
    Psychiatry Clin Neurosci 59:570-5. 2005
    ....
  67. ncbi request reprint How best to identify a bipolar-related subtype among major depressive patients without spontaneous hypomania: superiority of age at onset criterion over recurrence and polarity?
    Franco Benazzi
    Hecker Psychiatry Research Center, Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 107:77-88. 2008
    ..History of high depressive recurrence (without history of mania/hypomania) has been proposed as a mood subtype close to bipolar disorders. Herein we test whether this is the best approach to this question...
  68. ncbi request reprint Agitated "unipolar" depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy
    Hagop S Akiskal
    Department of Psychiatry and International Mood Center, University of California, La Jolla, CA, USA
    J Affect Disord 85:245-58. 2005
    ..S., Mallya, G., 1987. Criteria for the "soft" bipolar spectrum: treatment implications. Psychopharmacol Bull. 23, 68-73]...
  69. ncbi request reprint Challenging DSM-IV criteria for hypomania: diagnosing based on number of no-priority symptoms
    Franco Benazzi
    Hecker Psychiatry Research Center at Forli, Forli, Italy
    Eur Psychiatry 22:99-103. 2007
    ..DSM-IV definition of hypomania of bipolar-II disorder (BP-II), which includes elevated/irritable mood change as core feature (i.e., it must always be present), is not based on sound evidence...
  70. ncbi request reprint Optimizing the detection of bipolar II disorder in outpatient private practice: toward a systematization of clinical diagnostic wisdom
    Hagop S Akiskal
    International Mood Center, University of California, San Diego, USA
    J Clin Psychiatry 66:914-21. 2005
    ....
  71. ncbi request reprint Atypical depression: a variant of bipolar II or a bridge between unipolar and bipolar II?
    Hagop S Akiskal
    International Mood Center, University of California at San Diego, V A Hospital, 3350 La Jolla Village Dr 116 A, La Jolla, San Diego, CA 92161, USA
    J Affect Disord 84:209-17. 2005
    ..Accordingly, we undertook a full scale validation of such a link in a large clinical sample of BP-II and unipolar (UP) major depressive disorder (MDD)...
  72. ncbi request reprint Symptoms of depression as possible markers of bipolar II disorder
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 30:471-7. 2006
    ..The study aim was to find which symptoms of depression could be possible cross-sectional markers of BP-II, in order to reduce underdiagnosing BP-II...
  73. ncbi request reprint The continuum/spectrum concept of mood disorders: is mixed depression the basic link?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Eur Arch Psychiatry Clin Neurosci 256:512-5. 2006
    ..No bi-modality, and a dose-response relationship, would not support a categorical distinction...
  74. ncbi request reprint Testing new diagnostic criteria for hypomania
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Ann Clin Psychiatry 19:99-104. 2007
    ..Angst has suggested new criteria for hypomania, giving priority to overactivity. Study aim was to test the validity of Angst's diagnostic criteria for hypomania...
  75. ncbi request reprint Psychometric delineation of the most discriminant symptoms of depressive mixed states
    Franco Benazzi
    Hecker Psychiatry Research Center, Ravenna, Italy
    Psychiatry Res 141:81-8. 2006
    ..Beyond its diagnostic significance, the foregoing signs and symptoms are among the clinical features the FDA lists as presaging "suicidality" on antidepressant monotherapy...
  76. ncbi request reprint A tetrachoric factor analysis validation of mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 32:186-92. 2008
    ..However, its diagnostic validity and bipolar nature are still not firmly supported. A bipolar nature could have significant treatment impacts...
  77. ncbi request reprint Irritable-hostile depression: further validation as a bipolar depressive mixed state
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 84:197-207. 2005
    ..A veritable tower of Babel indeed. In the present analyses, our aim was to extend previous research on irritable-hostile depression to more specific parameters of bipolarity and depressive mixed state (DMX)...
  78. doi request reprint Is a family history of bipolar disorder a risk factor for migraine among affectively ill patients?
    Steven C Dilsaver
    Comprehensive Doctors Medical Group, Arcadia, Calif, USA
    Psychopathology 42:119-23. 2009
    ..The aim was to determine whether having a family history of bipolar disorder (BPD) or unipolar major depressive disorder (MDD) is associated with an increased likelihood of having migraine headaches...
  79. ncbi request reprint Major depressive episodes with hypomanic symptoms are common among depressed outpatients
    F Benazzi
    Department of Psychiatry, , , Italy
    Compr Psychiatry 42:139-43. 2001
    ..0% of bipolar II subjects. These findings have important treatment implications, as antidepressants may worsen the symptoms of depressive mixed states, and mood stabilizers can be useful...
  80. ncbi request reprint Impact of temperamental mood lability on depressive mixed state
    Franco Benazzi
    Hecker Psychiatry Research Center, Ravenna, Italy
    Psychopathology 39:19-24. 2006
    ..The study aim was to find the impact of temperamental mood lability (TML) on DMX...
  81. ncbi request reprint Toward a clinical delineation of dysphoric hypomania - operational and conceptual dilemmas
    Hagop S Akiskal
    International Mood Center, University of California at San Diego, La Jolla, 92161, USA
    Bipolar Disord 7:456-64. 2005
    ..Analogous to the DSM-IV approach in the diagnosis of manic mixed state, in this exploratory study we operationalized DH as coexisting full syndromal hypomanic and major depressive states...
  82. ncbi request reprint Family history validation of the bipolar nature of depressive mixed states
    Hagop S Akiskal
    VA Medical Center, University of California at San Diego, VA Psychiatry Service 116 A, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
    J Affect Disord 73:113-22. 2003
    ..Our aims were to find the sensitivity and specificity of DMX for the diagnosis of bipolar II disorder, and validate it against familial bipolarity...
  83. ncbi request reprint Is there a link between atypical and early-onset "unipolar" depression and bipolar II disorder?
    Franco Benazzi
    Outpatient Psychiatry Center, a University of California San Diego Collaborating Center, Ravenna and Forli, and Department of Psychiatry, National Health Service of Forlì, Italy
    Compr Psychiatry 44:102-9. 2003
    ..These results support a link of atypical and early-onset "unipolar" depression with bipolar II disorder, and support Pages and Dunner's suggestion to combine bipolar II and recurrent unipolar into a single group...
  84. doi request reprint Classifying mood disorders by age-at-onset instead of polarity
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 33:86-93. 2009
    ..A reshaping of the classification of mood disorders thus seems required. Age-at-onset and recurrence have been suggested to be more clinically and genetically useful in the phenotyping of mood disorders...
  85. ncbi request reprint Late-life depression in private practice depressed outpatients: a 203-case study
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Int J Geriatr Psychiatry 13:145-8. 1998
    ..To establish the prevalence of late-life depression in unipolar/bipolar depressed outpatients in private practice, to compare it with depression in younger patients and to compare its early/late-onset subtypes...
  86. ncbi request reprint Prevalence of bipolar II disorder in outpatient depression: a 203-case study in private practice
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    J Affect Disord 43:163-6. 1997
    ....
  87. ncbi request reprint Bipolar II depression with melancholic features
    F Benazzi
    Department of Psychiatry, National Health Service AUSL, Forli, Italy
    Ann Clin Psychiatry 12:29-33. 2000
    ..The prevalence of melancholic features in bipolar II depression in private practice was higher than previously reported in academic centers...
  88. ncbi request reprint Impulsivity in bipolar-II disorder: trait, state, or both?
    Franco Benazzi
    University of California at San Diego, CA, USA
    Eur Psychiatry 22:472-8. 2007
    ..In bipolar-II (BP-II) disorder impulsivity (defined as excessive risky activities by DSM-IV-TR) is one of the symptoms of hypomania. It is unclear if impulsivity is also a trait in BP-II...
  89. ncbi request reprint The DSM-IV and ICD-10 categories of recurrent [major] depressive and bipolar II disorders: evidence that they lie on a dimensional spectrum
    Hagop S Akiskal
    International Mood Center, University of California at San Diego, VA Psychiatry Service, 116A, 3350 La Jolla Village Drive, 92161, USA
    J Affect Disord 92:45-54. 2006
    ..We used the ongoing Ravenna-San Diego Collaboration database to examine this question with respect to major depressive disorder (MDD) and bipolar II (BP-II)...
  90. ncbi request reprint Highly recurrent unipolar may be related to bipolar II
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Compr Psychiatry 43:263-8. 2002
    ..Pages and Dunner (1997) view that recurrent unipolar and bipolar II could be part of a single mood disorder, and Goodwin and Jamison (1990) view that recurrence is the key feature of mood disorders are partly supported by the findings...
  91. ncbi request reprint Psychomotor changes in melancholic and atypical depression: unipolar and bipolar-II subtypes
    Franco Benazzi
    Department of Psychiatry, National Health Service, and Outpatient Psychiatry Private Center, Forli, Italy
    Psychiatry Res 112:211-20. 2002
    ..5 vs. 0.0%). Logistic regression controlling for age, gender and illness duration had little effect on the findings, which suggests that psychomotor changes are not core features of melancholic MDE...
  92. ncbi request reprint Delineation of the clinical picture of Dysphoric/Mixed Hypomania
    Franco Benazzi
    Hecker Psychiatry Research Center, University of California at San Diego, USA
    Prog Neuropsychopharmacol Biol Psychiatry 31:944-51. 2007
    ..e. combination of syndromal hypomania and depression) compared to Bipolar I Disorder Mixed State (i.e. combination of syndromal mania and depression)...
  93. ncbi request reprint Testing predictors of bipolar-II disorder with a 2-day minimum duration of hypomania
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Psychiatry Res 153:153-62. 2007
    ..As PPV is related to disease prevalence, findings need to be replicated in different settings...
  94. ncbi request reprint Bipolar family history of the hypomanic symptoms and dimensions of mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Ravenna, Italy
    Compr Psychiatry 46:399-404. 2005
    ..These data may be important for the genetics of mixed depression. The study aim was to investigate the BPFH of the hypomanic symptoms of mixed depression...
  95. ncbi request reprint Bipolar II depressive mixed state: finding a useful definition
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Compr Psychiatry 44:21-7. 2003
    ..A cross-sectional marker like DMX3 may increase the probability of making the correct diagnosis of bipolar II, and therefore may be a useful definition of DMX...
  96. ncbi request reprint Reviewing the diagnostic validity and utility of mixed depression (depressive mixed states)
    Franco Benazzi
    Hecker Psychiatry Research Center, University of California at San Diego, San Diego, CA, USA
    Eur Psychiatry 23:40-8. 2008
    ..To review the diagnostic validity and utility of mixed depression, i.e. co-occurrence of depression and manic/hypomanic symptoms...
  97. ncbi request reprint Can only reversed vegetative symptoms define atypical depression?
    Franco Benazzi
    Outpatient Psychiatry Center, Ravenna and Forli, Italy
    Eur Arch Psychiatry Clin Neurosci 252:288-93. 2002
    ....
  98. doi request reprint A prediction rule for diagnosing hypomania
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli IT, a University of California at San Diego Collaborating Center, San Diego, USA
    Prog Neuropsychopharmacol Biol Psychiatry 33:317-22. 2009
    ..Missing the diagnosis of past hypomania, and thus of bipolar II disorder, is common. Study aim was to find a 'prediction rule' for facilitating the diagnosis of past hypomania...
  99. ncbi request reprint Challenging the unipolar-bipolar division: does mixed depression bridge the gap?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 31:97-103. 2007
    ..A correlation between intradepressive hypomanic symptoms and depressive symptoms could support such a continuum, but other explanations of a correlation are possible...
  100. ncbi request reprint Bipolar II depression in late life: prevalence and clinical features in 525 depressed outpatients
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, 47100 Forli, Italy
    J Affect Disord 66:13-8. 2001
    ....
  101. ncbi request reprint Does temperamental instability support a continuity between bipolar II disorder and major depressive disorder?
    F Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Eur Psychiatry 21:274-9. 2006
    ..According to Kraepelin, temperamental instability was the "foundation" of his unitary view of mood disorders...