C Becattini

Summary

Affiliation: University of Perugia
Country: Italy

Publications

  1. ncbi request reprint Treatment of DVT: how long is enough and how do you predict recurrence
    Giancarlo Agnelli
    Division of Internal and Cardiovascular Medicine, University of Perugia, Via G Dottori 1, Perugia, Italy
    J Thromb Thrombolysis 25:37-44. 2008
  2. ncbi request reprint Computed tomography to assess risk of death in acute pulmonary embolism: a meta-analysis
    Cecilia Becattini
    Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy
    Eur Respir J 43:1678-90. 2014
  3. ncbi request reprint Aspirin for prevention and treatment of venous thromboembolism
    Cecilia Becattini
    Internal and Cardiovascular Medicine, Stroke Unit, University of Perugia, Perugia, Italy Electronic address
    Blood Rev 28:103-8. 2014
  4. ncbi request reprint Long-term Treatment of Venous Thromboembolism
    Cecilia Becattini
    Internal and Cardiovascular Medicine Stroke Unit, University of Perugia, Piazzale Menghini 1, 06129 Perugia, Italy
    Curr Vasc Pharmacol 12:384-92. 2014
  5. doi request reprint Aspirin for preventing the recurrence of venous thromboembolism
    Cecilia Becattini
    Division of Internal and Cardiovascular Medicine and Stroke Unit, Department of Internal Medicine, University of Perugia, Perugia, Italy
    N Engl J Med 366:1959-67. 2012
  6. ncbi request reprint New oral anticoagulants for venous thromboembolism: focus on factor Xa and thrombin inhibitors
    Cecilia Becattini
    Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy
    Curr Drug Discov Technol 9:119-28. 2012
  7. doi request reprint Old and new oral anticoagulants for venous thromboembolism and atrial fibrillation: a review of the literature
    Cecilia Becattini
    Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Italy
    Thromb Res 129:392-400. 2012
  8. doi request reprint Venous thromboembolism after laparoscopic bariatric surgery for morbid obesity: clinical burden and prevention
    Cecilia Becattini
    Division of Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy
    Surg Obes Relat Dis 8:108-15. 2012
  9. doi request reprint Incidence of arterial cardiovascular events after venous thromboembolism: a systematic review and a meta-analysis
    C Becattini
    Division of Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Varese, Italy
    J Thromb Haemost 8:891-7. 2010
  10. doi request reprint Diagnosis and prognosis of acute pulmonary embolism: focus on serum troponins
    Cecilia Becattini
    Dipartimento di Medicina Interna, Medicina Interna e Cardiovascolare, Stroke Unit, Universita di Perugia, Perugia, Italy
    Expert Rev Mol Diagn 8:339-49. 2008

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Treatment of DVT: how long is enough and how do you predict recurrence
    Giancarlo Agnelli
    Division of Internal and Cardiovascular Medicine, University of Perugia, Via G Dottori 1, Perugia, Italy
    J Thromb Thrombolysis 25:37-44. 2008
    ..At the end of this treatment period physicians should decide for definitive withdrawal or indefinite anticoagulation with scheduled periodic re-assessment of the benefit from extending anticoagulation...
  2. ncbi request reprint Computed tomography to assess risk of death in acute pulmonary embolism: a meta-analysis
    Cecilia Becattini
    Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy
    Eur Respir J 43:1678-90. 2014
    ..65 (95% CI 1.79-12.07); p=0.002). Right-to-left ventricle dilation as assessed by CT angiography can be used to evaluate risk of death in all-comers with pulmonary embolism and in haemodynamically stable patients. ..
  3. ncbi request reprint Aspirin for prevention and treatment of venous thromboembolism
    Cecilia Becattini
    Internal and Cardiovascular Medicine, Stroke Unit, University of Perugia, Perugia, Italy Electronic address
    Blood Rev 28:103-8. 2014
    ..Given its safety, worldwide availability and low cost, aspirin can be considered a valid alternative to oral anticoagulants for the extended treatment of venous thromboembolism after a first unprovoked event. ..
  4. ncbi request reprint Long-term Treatment of Venous Thromboembolism
    Cecilia Becattini
    Internal and Cardiovascular Medicine Stroke Unit, University of Perugia, Piazzale Menghini 1, 06129 Perugia, Italy
    Curr Vasc Pharmacol 12:384-92. 2014
    ..New anticoagulants with more favourable efficacy- safety profile and reduced need for monitoring could improve the feasibility of extended anticoagulation. ..
  5. doi request reprint Aspirin for preventing the recurrence of venous thromboembolism
    Cecilia Becattini
    Division of Internal and Cardiovascular Medicine and Stroke Unit, Department of Internal Medicine, University of Perugia, Perugia, Italy
    N Engl J Med 366:1959-67. 2012
    ..Extending anticoagulation prevents recurrences but is associated with increased bleeding. The benefit of aspirin for the prevention of recurrent venous thromboembolism is unknown...
  6. ncbi request reprint New oral anticoagulants for venous thromboembolism: focus on factor Xa and thrombin inhibitors
    Cecilia Becattini
    Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy
    Curr Drug Discov Technol 9:119-28. 2012
    ..Clinical trials on VTE treatment are currently ongoing with apixaban and edoxaban. A number of phase II clinical trials are currently ongoing with several other antiXa agents in the prophylaxis and treatment of VTE...
  7. doi request reprint Old and new oral anticoagulants for venous thromboembolism and atrial fibrillation: a review of the literature
    Cecilia Becattini
    Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Italy
    Thromb Res 129:392-400. 2012
    ..In these patients rivaroxaban and apixaban reduced the incidence of hemorrhagic stroke with a similar incidence of ischemic stroke. No bleeding concern emerged with the new anticoagulant agents in this indication...
  8. doi request reprint Venous thromboembolism after laparoscopic bariatric surgery for morbid obesity: clinical burden and prevention
    Cecilia Becattini
    Division of Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy
    Surg Obes Relat Dis 8:108-15. 2012
    ..The clinical benefit of prophylaxis for venous thromboembolism (VTE) in laparoscopic bariatric surgery is unclear. Our objective was to assess the clinical burden of VTE after laparoscopic bariatric surgery...
  9. doi request reprint Incidence of arterial cardiovascular events after venous thromboembolism: a systematic review and a meta-analysis
    C Becattini
    Division of Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Varese, Italy
    J Thromb Haemost 8:891-7. 2010
    ..Whether patients with unprovoked venous thromboembolism (VTE) have a higher risk of arterial cardiovascular events than the general population and patients with provoked VTE is a matter of debate...
  10. doi request reprint Diagnosis and prognosis of acute pulmonary embolism: focus on serum troponins
    Cecilia Becattini
    Dipartimento di Medicina Interna, Medicina Interna e Cardiovascolare, Stroke Unit, Universita di Perugia, Perugia, Italy
    Expert Rev Mol Diagn 8:339-49. 2008
    ..Elevated serum levels of troponins are associated with right ventricular overload and adverse in-hospital outcomes in patients with pulmonary embolism and normal blood pressure...
  11. doi request reprint Bolus tenecteplase for right ventricle dysfunction in hemodynamically stable patients with pulmonary embolism
    Cecilia Becattini
    Medicina Interna e Cardiovascolare Stroke Unit, Universita di Perugia, Perugia, Italy
    Thromb Res 125:e82-6. 2010
    ..In these patients bolus tenecteplase has the potential to provide an effective and safe thrombolysis...
  12. ncbi request reprint Prognostic value of troponins in acute pulmonary embolism: a meta-analysis
    Cecilia Becattini
    Medicina Interna e Cardiovascolare, Dipartimento di Medicina Interna, University of Perugia, Via G Dottori 1, 06129 Perugia, Italy
    Circulation 116:427-33. 2007
    ..Whether elevated serum troponin levels identify patients with acute pulmonary embolism at high risk of short-term mortality or adverse outcome is undefined...
  13. doi request reprint Bosentan for chronic thromboembolic pulmonary hypertension: findings from a systematic review and meta-analysis
    Cecilia Becattini
    Internal and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Perugia, Italy
    Thromb Res 126:e51-6. 2010
    ..We performed a systematic review and meta-analysis aimed at assessing the effects of bosentan therapy in patients with CTEPH...
  14. ncbi request reprint [Determinants of prognosis in acute pulmonary embolism: the role of serum troponins]
    Cecilia Becattini
    Medicina Interna e Cardiovascolare, Universita, Perugia
    Recenti Prog Med 99:509-15. 2008
    ..Future studies will evaluate the clinical benefit of thrombolytic treatment in hemodynamically stable patients with acute pulmonary embolism at high risk for adverse outcome...
  15. doi request reprint Multidetector computed tomography for acute pulmonary embolism: diagnosis and risk stratification in a single test
    Cecilia Becattini
    Stroke Unit, Department of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy
    Eur Heart J 32:1657-63. 2011
    ....
  16. doi request reprint D-dimer for risk stratification in patients with acute pulmonary embolism
    Cecilia Becattini
    Internal and Cardiovascular Medicine Stroke Unit, University of Perugia, Perugia, Italy
    J Thromb Thrombolysis 33:48-57. 2012
    ..Risk stratification is currently recommended for the initial management of patients with acute pulmonary embolism (PE)...
  17. ncbi request reprint Prognostic role of sentinel node biopsy in patients with thick melanoma: a meta-analysis
    F Rondelli
    Department of Surgery, University of Perugia, Perugia, Italy
    J Eur Acad Dermatol Venereol 26:560-5. 2012
    ..0 mm). We performed a meta-analysis to assess the prognostic role of SLN in thick melanoma in terms of disease-free survival (DFS) and overall survival (OS)...
  18. doi request reprint Prevalence and clinical history of incidental, asymptomatic pulmonary embolism: a meta-analysis
    F Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    Thromb Res 125:518-22. 2010
    ..Natural history of incidental PE remains unclear...
  19. doi request reprint Patients with primary antiphospholipid antibody syndrome and without associated vascular risk factors present a normal endothelial function
    P Gresele
    Department of Internal Medicine, University of Perugia, Via E dal Pozzo, 06126 Perugia, Italy
    Thromb Res 123:444-51. 2009
    ..Endothelial dysfunction is an early event in the natural history of atherosclerosis. Aim of our study was to compare endothelial function of patients with PAPS and no associated risk factors with that of age- and sex-matched controls...
  20. ncbi request reprint Acute pulmonary embolism: risk stratification in the emergency department
    C Becattini
    Sezione di Medicina Interna e Cardiovascolare, Dipartimento di Medicina Interna, Universita di Perugia, Via G Dottori 1, I 06129, Perugia, Italy
    Intern Emerg Med 2:119-29. 2007
    ..These patients could afford the trade-off of an increased risk of side effects related to a more aggressive treatment, such as thrombolysis or surgical or interventional procedures...
  21. ncbi request reprint Initial treatment of venous thromboembolism
    Cecilia Becattini
    Division of Internal and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Italy
    Thromb Haemost 96:242-50. 2006
    ..An oral anticoagulant agent to be used without laboratory monitoring for both acute and long-term treatment of VTE remains an unsolved clinical need in the treatment of VTE...
  22. ncbi request reprint Incidence of cancer after a first episode of idiopathic venous thromboembolism treated with 3 months or 1 year of oral anticoagulation
    M R Taliani
    Sezione di Medicina Interna e Cardiovascolare, Dipartimento di Medicina Interna, Universita di Perugia, Perugia, Italy
    J Thromb Haemost 1:1730-3. 2003
    ..A prolonged treatment with oral anticoagulants has been claimed to reduce the incidence of newly diagnosed cancer in the long-term follow-up of patients with venous thromboembolism...
  23. pmc New anticoagulants for the prevention of venous thromboembolism
    Cecilia Becattini
    Internal and Cardiovascular, Medicine and Stroke Unit, University of Perugia, Italy
    Drug Des Devel Ther 4:49-60. 2010
    ..Differences in pharmacokinetics and pharmacodynamics could offer the potential for individualized anticoagulant therapies in the near future...
  24. ncbi request reprint Direct thrombin inhibitors for the prevention of venous thromboembolism after major orthopaedic surgery
    Giancarlo Agnelli
    Stroke Unit and Division of Internal and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Italy
    Curr Pharm Des 11:3885-91. 2005
    ....
  25. ncbi request reprint Thrombolysis vs heparin in the treatment of pulmonary embolism: a clinical outcome-based meta-analysis
    Giancarlo Agnelli
    Sezione di Medicina Interna e Cardiovascolare, Dipartimento di Medicina Interna, Universita degli Studi di Perugia, Via Enrico Dal Pozzo, I 06123 Perugia, Italy
    Arch Intern Med 162:2537-41. 2002
    ..Whether this advantage results in an improved clinical outcome is unclear. We sought to perform a clinical outcome-based meta-analysis of studies comparing thrombolytic and heparin treatment in patients with pulmonary embolism...
  26. ncbi request reprint Extended oral anticoagulant therapy after a first episode of pulmonary embolism
    Giancarlo Agnelli
    Sezione di Medicina Interna e Cardiovascolare, Dipartimento di Medicina Interna, Universita di Perugia, Via Enrico Dal Pozzo, 06123 Perugia, Italy
    Ann Intern Med 139:19-25. 2003
    ..The optimal duration of oral anticoagulant treatment after a first episode of pulmonary embolism remains uncertain...
  27. ncbi request reprint Duration of anticoagulant treatment after venous thromboembolism
    Cecilia Becattini
    Department of Internal Medicine, University of Perugia, Perugia, Italy
    Pathophysiol Haemost Thromb 33:354-7. 2003
  28. ncbi request reprint Long-term therapy of pulmonary embolism
    Giancarlo Agnelli
    Division of Internal Medicine and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Perugia, Italy
    Ital Heart J 6:824-9. 2005
    ..Due to the limitations of the currently available oral anticoagulant agents, search for the optimal agent to be used in the long-term treatment of pulmonary embolism is still open...
  29. ncbi request reprint New anticoagulants
    Giancarlo Agnelli
    Internal and Cardiovascular Medicine and Stroke Unit, Department of Internal Medicine, University of Perugia, Perugia, Italy
    Semin Thromb Hemost 32:793-802. 2006
    ..Some of them have been approved for clinical use, others are in advanced phase of clinical development, and some are still in the initial phase of investigation...
  30. doi request reprint To drain or not to drain extraperitoneal colorectal anastomosis? A systematic review and meta-analysis
    F Rondelli
    San Giovanni Battista Hospital, Foligno, Perugia, Italy Department of Surgery, School of Medicine, University of Perugia, Perugia, Italy
    Colorectal Dis 16:O35-42. 2014
    ..Although many studies have compared drained and undrained colorectal anastomoses, to date the role of pelvic drainage in extraperitoneal colorectal anastomosis remains undefined...
  31. ncbi request reprint Venous thromboembolism and atherosclerosis: common denominators or different diseases?
    G Agnelli
    Department of Internal Medicine, Division of Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy
    J Thromb Haemost 4:1886-90. 2006
  32. ncbi request reprint Clinical and economic aspects of managing venous thromboembolism in the outpatient setting
    G Agnelli
    Division of Internal and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Perugia, Italy
    Semin Hematol 38:58-66. 2001
    ....
  33. ncbi request reprint Risk factors for adverse short-term outcome in patients with pulmonary embolism
    C Becattini
    Sezione di Medicina Interna e Cardiovascolare, Dipartimento di Medicina Interna, , Perugia, Italy
    Thromb Res 103:V239-44. 2001
    ..However, such treatments are invariably associated with bleeding and other procedural complications...
  34. ncbi request reprint Endothelial dysfunction in patients with spontaneous venous thromboembolism
    Rino Migliacci
    Division of Internal and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Perugia, Italy
    Haematologica 92:812-8. 2007
    ..Endothelial dysfunction is an early marker of atherosclerosis and has predictive value for ischemic events. We have evaluated endothelial function in patients with a history of spontaneous venous thromboembolism...
  35. ncbi request reprint A prospective study on cardiovascular events after acute pulmonary embolism
    Cecilia Becattini
    Sezione di Medicina Interna e Cardiovascolare, Dipartimento di Medicina Interna, Universita di Perugia, Via Enrico Dal Pozzo, 06126 Perugia, Italy
    Eur Heart J 26:77-83. 2005
    ..To evaluate the incidence of cardiovascular events in the long-term clinical course of patients with a first episode of symptomatic, objectively confirmed pulmonary embolism...
  36. ncbi request reprint Incidence of chronic thromboembolic pulmonary hypertension after a first episode of pulmonary embolism
    Cecilia Becattini
    Dipartimento di Medicina Interna, Medicina Interna e Cardiovascolare, Universita di Perugia, Via G Dottori, Ospedale Silvestrini, 06129 Perugia, Italy
    Chest 130:172-5. 2006
    ..To assess the incidence of chronic thromboembolic pulmonary hypertension (CTPH) after the first episode of objectively confirmed pulmonary embolism (PE)...
  37. doi request reprint Prognostic role of embolic burden assessed at computed tomography angiography in patients with acute pulmonary embolism: systematic review and meta-analysis
    M C Vedovati
    Department of Internal and Cardiovascular Medicine Stroke Unit, University of Perugia, Perugia, Italy
    J Thromb Haemost 11:2092-102. 2013
    ..Whether embolic burden assessed at computed tomography (CT) angiography has a role in risk stratification in these patients is debated...
  38. ncbi request reprint Cardiovascular risk factors and venous thromboembolism: a meta-analysis
    Walter Ageno
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Circulation 117:93-102. 2008
    ..We performed a meta-analysis to assess the association between cardiovascular risk factors and VTE...
  39. doi request reprint Combined oral anticoagulants and antiplatelets: benefits and risks
    Maria Cristina Vedovati
    Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy
    Intern Emerg Med 5:281-90. 2010
    ..Thus, a combined regimen of anticoagulant and antiplatelet therapy should be reserved for selected patients at high risk of thromboembolic events who have a low risk of bleeding...
  40. ncbi request reprint Pathogenesis of venous thromboembolism
    Cecilia Becattini
    Sezione di Medicina Interna e Cardiovascolare, Dipartimento di Medicina Interna, Universita di Perugia, Perugia, Italy
    Curr Opin Pulm Med 8:360-4. 2002
    ..Vessel wall has a remarkable role in protecting against and in promoting thrombosis. The role of inflammation on venous thrombosis is under investigation...
  41. ncbi request reprint The sentinel node biopsy in patients with thick melanoma: outcome analysis from a single-institution database
    P Covarelli
    Department of Surgery, University of Perugia, 06100 Perugia, Italy
    In Vivo 25:439-43. 2011
    ..We examined the impact of sentinel lymph node (SLN) biopsy among patients with primary melanoma that exceeded 4.0 mm in Breslow thickness, treated in our Institution from 1998 until 2009...
  42. ncbi request reprint Recurrent venous thromboembolism in men and women
    Giancarlo Agnelli
    N Engl J Med 351:2015-8; author reply 2015-8. 2004
  43. ncbi request reprint Association of persistent right ventricular dysfunction at hospital discharge after acute pulmonary embolism with recurrent thromboembolic events
    Stefano Grifoni
    Emergency Department, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Arch Intern Med 166:2151-6. 2006
    ..The aim of this study was to evaluate the prognostic value of RVD persistence at hospital discharge with regard to the likelihood of recurrent venous thromboembolism (VTE)...