Daniela Basso

Summary

Affiliation: University Hospital
Country: Italy

Publications

  1. doi Inflammation and pancreatic cancer: molecular and functional interactions between S100A8, S100A9, NT-S100A8 and TGFβ1
    Daniela Basso
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Cell Commun Signal 12:20. 2014
  2. pmc Pancreatic tumors and immature immunosuppressive myeloid cells in blood and spleen: role of inhibitory co-stimulatory molecules PDL1 and CTLA4. An in vivo and in vitro study
    Daniela Basso
    Department of Medicine, University of Padova, Padova, Italy
    PLoS ONE 8:e54824. 2013
  3. doi Pathogenesis of Helicobacter pylori infection
    Daniela Basso
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2, Padua, Italy
    Helicobacter 15:14-20. 2010
  4. ncbi Clarithromycin resistance, tumor necrosis factor alpha gene polymorphism and mucosal inflammation affect H. pylori eradication success
    Carlo Federico Zambon
    Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    J Gastrointest Surg 11:1506-14; discussion 1514. 2007
  5. ncbi Pro- and anti-inflammatory cytokines gene polymorphisms and Helicobacter pylori infection: interactions influence outcome
    Carlo F Zambon
    Department of Medical and Surgical Sciences, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
    Cytokine 29:141-52. 2005
  6. doi Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Gastroenterology 135:91-9. 2008
  7. doi Antibodies against synthetic deamidated gliadin peptides for celiac disease diagnosis and follow-up in children
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Italy
    Clin Chem 55:150-7. 2009
  8. doi Chemiluminescence and ELISA-based serum assays for diagnosing and monitoring celiac disease in children: a comparative study
    Ada Aita
    Department of Medicine DIMED, University of Padova, Padova, Italy
    Clin Chim Acta 421:202-7. 2013
  9. doi Oxidative DNA damage in gastric cancer: CagA status and OGG1 gene polymorphism
    Fabio Farinati
    Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Universita di Padova, Padova, Italy
    Int J Cancer 123:51-5. 2008
  10. ncbi Non-invasive diagnosis of Helicobacter pylori infection: simplified 13C-urea breath test, stool antigen testing, or DNA PCR in human feces in a clinical laboratory setting?
    Carlo Federico Zambon
    Department of Medical and Surgical Sciences, University of Padova, Italy
    Clin Biochem 37:261-7. 2004

Collaborators

Detail Information

Publications48

  1. doi Inflammation and pancreatic cancer: molecular and functional interactions between S100A8, S100A9, NT-S100A8 and TGFβ1
    Daniela Basso
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Cell Commun Signal 12:20. 2014
    ..NF-κB, Akt and mTOR pathways, Cai2+ and EMT were studied in well (Capan1 and BxPC3) and poorly differentiated (Panc1 and MiaPaCa2) cell lines...
  2. pmc Pancreatic tumors and immature immunosuppressive myeloid cells in blood and spleen: role of inhibitory co-stimulatory molecules PDL1 and CTLA4. An in vivo and in vitro study
    Daniela Basso
    Department of Medicine, University of Padova, Padova, Italy
    PLoS ONE 8:e54824. 2013
    ....
  3. doi Pathogenesis of Helicobacter pylori infection
    Daniela Basso
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2, Padua, Italy
    Helicobacter 15:14-20. 2010
    ..Among those are studies on the genetic variation of genes encoding outer membrane proteins and the mimicry of host antigens, factors that alter host-cell metabolism and factors that modulate the host's immune response...
  4. ncbi Clarithromycin resistance, tumor necrosis factor alpha gene polymorphism and mucosal inflammation affect H. pylori eradication success
    Carlo Federico Zambon
    Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    J Gastrointest Surg 11:1506-14; discussion 1514. 2007
    ....
  5. ncbi Pro- and anti-inflammatory cytokines gene polymorphisms and Helicobacter pylori infection: interactions influence outcome
    Carlo F Zambon
    Department of Medical and Surgical Sciences, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
    Cytokine 29:141-52. 2005
    ..In conclusion, among host genetic factors contributing to H. pylori disease outcome, IFN-G +874 AA genotype favors cagA positive infections, TNF-A -857 TT duodenal ulcer while IL-10 -819 TT intestinal metaplasia and NCGC...
  6. doi Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Gastroenterology 135:91-9. 2008
    ..We assessed the association of new and established cagA and vacA polymorphisms with disease...
  7. doi Antibodies against synthetic deamidated gliadin peptides for celiac disease diagnosis and follow-up in children
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Italy
    Clin Chem 55:150-7. 2009
    ..AGA IgA II and AGA IgG II have recently been suggested as reliable tools for celiac disease (CD) diagnosis. We compared their utility for diagnosis and monitoring CD in children with that of tTG IgA, an established CD marker...
  8. doi Chemiluminescence and ELISA-based serum assays for diagnosing and monitoring celiac disease in children: a comparative study
    Ada Aita
    Department of Medicine DIMED, University of Padova, Padova, Italy
    Clin Chim Acta 421:202-7. 2013
    ....
  9. doi Oxidative DNA damage in gastric cancer: CagA status and OGG1 gene polymorphism
    Fabio Farinati
    Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Universita di Padova, Padova, Italy
    Int J Cancer 123:51-5. 2008
    ..OGG1 1245C-->G polymorphism was common in both GC and IMA, but very rare in controls, and correlated more closely with 8-OHdG levels than do H. pylori infection or cagA status...
  10. ncbi Non-invasive diagnosis of Helicobacter pylori infection: simplified 13C-urea breath test, stool antigen testing, or DNA PCR in human feces in a clinical laboratory setting?
    Carlo Federico Zambon
    Department of Medical and Surgical Sciences, University of Padova, Italy
    Clin Biochem 37:261-7. 2004
    ..2) To ascertain whether a simplified UBT (breath collection time = 10 min) is as reliable as the standard assay (30 min)...
  11. doi Pancreatic cancer biomarkers discovery by surface-enhanced laser desorption and ionization time-of-flight mass spectrometry
    Filippo Navaglia
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Clin Chem Lab Med 47:713-23. 2009
    ..The aim of the present study was to explore the application of SELDI proteomic patterns in serum for distinguishing between cases of pancreatic cancer, chronic pancreatitis, type 2 diabetes mellitus and healthy controls...
  12. doi Altered intracellular calcium fluxes in pancreatic cancer induced diabetes mellitus: Relevance of the S100A8 N-terminal peptide (NT-S100A8)
    Daniela Basso
    Department of Laboratory Medicine, University of Padua, Padua, Italy
    J Cell Physiol 226:456-68. 2011
    ....
  13. doi IL-4 -588C>T polymorphism and IL-4 receptor alpha [Ex5+14A>G; Ex11+828A>G] haplotype concur in selecting H. pylori cagA subtype infections
    Carlo Federico Zambon
    Department of Medical and Surgical Sciences, University of Padova, Italy
    Clin Chim Acta 389:139-45. 2008
    ..pylori virulence genes or H. pylori associated diseases...
  14. ncbi DNA repair pathways and mitochondrial DNA mutations in gastrointestinal carcinogenesis
    Daniela Basso
    Department of Laboratory Medicine, University Hospital of Padova, Via Giustiniani 2, 35128 Padova, Italy
    Clin Chim Acta 381:50-5. 2007
    ....
  15. ncbi Role of blood AFP mRNA and tumor grade in the preoperative prognostic evaluation of patients with hepatocellular carcinoma
    Umberto Cillo
    Clinica Chirurgica I Dipartimento di Scienze Chirurgiche e Gastroenterologiche Università degli Studi di Padova Via Giustiniani 2, Policlinico III Piano, 35128 Padova, Italy
    World J Gastroenterol 11:6920-5. 2005
    ....
  16. ncbi Mitochondrial DNA D-loop in pancreatic cancer: somatic mutations are epiphenomena while the germline 16519 T variant worsens metabolism and outcome
    Filippo Navaglia
    Department of Laboratory Medicine, University of Padova, Italy
    Am J Clin Pathol 126:593-601. 2006
    ....
  17. ncbi Pancreatic cancer-derived S-100A8 N-terminal peptide: a diabetes cause?
    Daniela Basso
    Department of Laboratory Medicine, University of Padua, Via Giustiniani 2, 35128 Padova, Italy
    Clin Chim Acta 372:120-8. 2006
    ..Our aim was to identify the pancreatic cancer diabetogenic peptide...
  18. doi Usefulness of MALDI-TOF/MS identification of low-MW fragments in sera for the differential diagnosis of pancreatic cancer
    Andrea Padoan
    Department of Laboratory Medicine, University of Padova, Italy
    Pancreas 42:622-32. 2013
    ..To identify new biomarkers of pancreatic cancer (PaCa), we performed MALDI-TOF/MS analysis of sera from 22 controls, 51 PaCa, 37 chronic pancreatitis, 24 type II diabetes mellitus (DM), 29 gastric cancer (GC), and 24 chronic gastritis (CG)...
  19. pmc Molecular refinement of clinical staging in hepatocellular carcinoma patients evaluated for potentially curative therapies
    Alessandro Vitale
    Unità di Chirurgia Epatobiliare e Trapianto Epatico, Dipartimento di Chirurgia Generale e Trapianti d Organo, Universita di Padova, Padova, Italy
    PLoS ONE 6:e23093. 2011
    ..VEGF and AFP mRNA determinations in the blood are promising prognostic factors for patients with HCC. This study explores their potential prognostic synergy in a cohort of HCC patients evaluated for potentially curative therapies...
  20. ncbi Fecal lactoferrin and calprotectin after ileocolonic resection for Crohn's disease
    Marco Scarpa
    Clinica Chirurgica I, Dipartimento di Scienze Chirurgiche e Gastroenterologiche, University of Padova, Padova, Italy
    Dis Colon Rectum 50:861-9. 2007
    ..This study was designed to assess the role of fecal lactoferrin and calprotectin as markers of intestinal inflammation in patients with Crohn's disease who have undergone ileocolonic resection...
  21. ncbi Analogs of vitamin E epitomized by alpha-tocopheryl succinate for pancreatic cancer treatment: in vitro results induce caution for in vivo applications
    Eliana Greco
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Pancreas 39:662-8. 2010
    ....
  22. ncbi Suicide gene therapy with the yeast fusion gene cytosine deaminase/uracil phosphoribosyltransferase is not enough for pancreatic cancer
    Paola Fogar
    Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Pancreas 35:224-31. 2007
    ..We ascertained whether gene therapy with FCY1-FUR1 is effective in killing pancreatic cancer cells after 5-fluorocytosine (5-FC) treatment...
  23. ncbi Retrovirus-mediated herpes simplex virus thymidine kinase gene transfer in pancreatic cancer cell lines: an incomplete antitumor effect
    Eliana Greco
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Pancreas 25:e21-9. 2002
    ..The transfer of drug-susceptible (suicide) genes to tumor cells by retroviral or adenoviral vectors is a novel approach to the treatment of human tumors...
  24. ncbi Maldi-TOF analysis of portal sera of pancreatic cancer patients: identification of diabetogenic and antidiabetogenic peptides
    Anna Valerio
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Clin Chim Acta 343:119-27. 2004
    ....
  25. doi Effectiveness of the combined evaluation of KLK3 genetics and free-to-total prostate specific antigen ratio for prostate cancer diagnosis
    Carlo Federico Zambon
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    J Urol 188:1124-30. 2012
    ..We ascertained whether the knowledge of KLK3 genetics would enhance prostate specific antigen diagnostic performance in patients with clinical suspicion of prostate cancer...
  26. ncbi Pancreatic cancer-associated diabetes mellitus: an open field for proteomic applications
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Via Giustiniani 2, Padova 35128, Italy
    Clin Chim Acta 357:184-9. 2005
    ..Clinical, epidemiological, and experimental data indicate that pancreatic cancer causes diabetes mellitus by releasing soluble mediators which interfere with both beta-cell function and liver and muscle glucose metabolism...
  27. ncbi Helicobacter pylori infection in children and adults: a single pathogen but a different pathology
    Nicoletta Gallo
    Department of Laboratory Medicine, University of Padova, Italy
    Helicobacter 8:21-8. 2003
    ..The aims of this retrospective study were to ascertain in large series of children and adults: the relationship of the infecting strain to gastric mucosal lesions; and the relationship of the infecting strain to its duodenal localization...
  28. doi New screening tests enrich anti-transglutaminase results and support a highly sensitive two-test based strategy for celiac disease diagnosis
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Clin Chim Acta 412:1662-7. 2011
    ..We compared the diagnostic accuracy of three new tests proposed for CD screening with that of the well established IgA tTG, and ascertained whether any combination of these tools might enhance accuracy in diagnosing CD...
  29. ncbi Decreased total lymphocyte counts in pancreatic cancer: an index of adverse outcome
    Paola Fogar
    Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Pancreas 32:22-8. 2006
    ..Our aim was to ascertain whether the immunophenotype pattern of blood lymphocytes in PC correlates with tumor stage, grade, or survival...
  30. doi VKORC1, CYP2C9 and CYP4F2 genetic-based algorithm for warfarin dosing: an Italian retrospective study
    Carlo Federico Zambon
    Department of Laboratory Medicine, University Hospital of Padua, 35128 Padua, Italy
    Pharmacogenomics 12:15-25. 2011
    ..A total of 371 patients under stable warfarin therapy were retrospectively selected to develop a pharmacogenetic algorithm to identify the individual maintenance dose...
  31. doi Immunotherapy for gastric premalignant lesions and cancer
    Valerio Zorzetto
    Department of Surgical, Oncological and Gastroenterological Sciences, Policlinico Universitario, Via Giustiniani 2, 35128 Padova, Italy
    Immunotherapy 4:587-99. 2012
    ..No study on immunotherapy of carcinoids is available but, in our experience, the administration of an antigastrin 17 vaccine induced carcinoid regression in two out of three patients treated...
  32. ncbi H. pylori infection: bacterial virulence factors and cytokine gene polymorphisms as determinants of infection outcome
    Daniela Basso
    Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy
    Crit Rev Clin Lab Sci 41:313-37. 2004
    ..pylori infection. This review focuses on the role of H. pylori virulence genes and on host cytokines' genes polymorphisms in determining clinical outcome to H. pylori infection...
  33. doi Decreased expression and promoter methylation of the menin tumor suppressor in pancreatic ductal adenocarcinoma
    Ilaria Cavallari
    Department of Oncology and Surgical Sciences, University of Padova, Via Gattamelata 64, Padova 35128, Italy
    Genes Chromosomes Cancer 48:383-96. 2009
    ..These findings represent the first evidence that the MEN1 gene is a target of mutation and methylation in PDAC and that menin influences the cell cycle profile of duct cells...
  34. ncbi Quantitative PSA mRNA determination in blood: a biochemical tool for scoring localized prostate cancer
    Carlo Federico Zambon
    Department of Medical and Surgical Sciences, University of Padova, Padua, Italy
    Clin Biochem 39:333-8. 2006
    ..Our aim was to verify whether the quantitative determination of PSA mRNA in circulating cells is helpful in diagnosing and scoring localized prostate cancer (PC)...
  35. doi Celiac disease in North Italian patients with autoimmune thyroid diseases
    Aglaura Cinzia Spadaccino
    Division of Endocrinology, Department of Medical and Surgical Sciences, University of Padova Medical School, Padova, Italy
    Autoimmunity 41:116-21. 2008
    ..An IgA deficiency is the most frequent immunodeficiency in humans and, in general, high frequency of this disorder was demonstrated in those with autoimmune diseases...
  36. doi Pancreatic cancer alters human CD4+ T lymphocyte function: a piece in the immune evasion puzzle
    Paola Fogar
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    Pancreas 40:1131-7. 2011
    ....
  37. ncbi A new indirect chemiluminescent immunoassay to measure anti-tissue transglutaminase antibodies
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Padova, Italy
    J Pediatr Gastroenterol Nutr 43:613-8. 2006
    ..p.A., Saluggia, Italy) in diagnosing and monitoring CD in children...
  38. doi Gastric type I carcinoid: a pilot study with human G17DT immunogen vaccination
    Chiara Tieppo
    Department of Surgical and Gastroenterological Sciences, Policlinico Universitario, Via Giustiniani 2, Padua, Italy
    Cancer Immunol Immunother 60:1057-60. 2011
    ..The approach to treatment, either endoscopic, medical or surgical, is not well defined, particularly in multifocal tumours or carcinoids with rapid growth/frequent recurrence...
  39. ncbi Clinical significance of alpha-fetoprotein mRNA in blood of patients with hepatocellular carcinoma
    Umberto Cillo
    Clinica Chirurgica I, Department of Surgical and Gastroenterological Sciences, University of Padua, School of Medicine, Via Giustiniani 2, Policlinico III Piano, 35128 Padova, Italy
    Clin Chim Acta 347:129-38. 2004
    ..The specificity of this molecular marker and its correlation with the main HCC clinical-pathological parameters remains controversial, however...
  40. ncbi Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms
    Carlo Federico Zambon
    Departments of Medical and Surgical Sciences, Laboratory Medicine, Oncological and Surgical Sciences, Gastroenterology, and Pathology, University of Padova, Padova, Italy
    Gastroenterology 126:382-4. 2004
  41. doi ERCC1 C8092A (rs3212986) polymorphism as a predictive marker in esophageal cancer patients treated with cisplatin/5-FU-based neoadjuvant therapy
    Enrica Rumiato
    aImmunology and Molecular Oncology Unit bOncological Surgery Unit, Veneto Institute of Oncology IOV IRCCS Departments of cLaboratory Medicine dSurgical Sciences, Oncology and Gastroenterology, University of Padova, Padova, Italy
    Pharmacogenet Genomics 23:597-604. 2013
    ....
  42. ncbi Enzymes in feces: useful markers of chronic inflammatory bowel disease
    Imerio Angriman
    Clinica Chirurgica I, Dipartimento di Scienze Chirurgiche e Gastroenterologiche, University of Padova, Italy
    Clin Chim Acta 381:63-8. 2007
    ..Ulcerative colitis and Crohn's disease are characterized by a chronic intestinal inflammation. Since the precise etiology is still unknown, current therapies are aimed at reducing or eliminating inflammation...
  43. ncbi Non-invasive assessment of chronic liver and gastric diseases
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Clin Chim Acta 381:39-49. 2007
    ..In these patients, precise definition of the hepatic fibrosis stage is the most important parameter to assess the risk of disease progression and to decide for an immediate and appropriate antiviral therapy...
  44. doi Addison's disease: a survey on 633 patients in Padova
    Corrado Betterle
    Endocrine Unit, Department of Medicine, University of Padova, Via Ospedale Civile, 105, 35128 Padova, Italy
    Eur J Endocrinol 169:773-84. 2013
    ..Addison's disease (AD) is a rare endocrine condition...
  45. doi Mass spectrometry measurement of plasma hepcidin for the prediction of iron overload
    Annarosa Floreani
    Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy
    Clin Chem Lab Med 49:197-206. 2011
    ..The aims of the study were 1) to assess the performance of this method in different conditions of iron metabolism disorders; 2) to assess the diagnostic validity of non-invasive serum biomarkers in the identification of iron overload...
  46. ncbi Putative pancreatic cancer-associated diabetogenic factor: 2030 MW peptide
    Daniela Basso
    Department of Laboratory Medicine, University of Padova, Italy
    Pancreas 24:8-14. 2002
    ..Pancreatic adenocarcinoma causes diabetes mellitus by releasing factors interfering with glucose metabolism...
  47. ncbi Efficacy of zinc supplementation in preventing acute hepatitis in Long-Evans Cinnamon rats
    Valentina Medici
    Section of Gastroenterology, Department of Surgical and Gastroenterological Sciences, University of Padova, Italy
    Liver Int 25:888-95. 2005
    ..The effect of oral zinc (Zn) acetate treatment on the development of acute hepatitis and the biochemical parameters of Cu-induced liver damage was studied in 5-week-old LEC rats (n=52)...