Research Topics
Species | C BassiSummaryAffiliation: University of Verona Country: Italy Publications
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Publications
Early versus late drain removal after standard pancreatic resections: results of a prospective randomized trialClaudio Bassi
Department of Surgery, G B Rossi Hospital, University of Verona, Verona, Italy
Ann Surg 252:207-14. 2010..The role of surgically placed intra-abdominal drainages after pancreatic resections has not been clearly established. In particular, their effect on morbidity rates and the optimal timing for their removal remains controversial...
Elevated urinary levels of urokinase-type plasminogen activator receptor (uPAR) in pancreatic ductal adenocarcinoma identify a clinically high-risk groupClaudio Sorio
Department of Pathology and Diagnostics, University of Verona, Italy
BMC Cancer 11:448. 2011..It is unknown whether the level of its soluble form (suPAR) in urine may be a diagnostic-prognostic marker in these patients...
High recurrence rate after atypical resection for pancreatic metastases from renal cell carcinomaC Bassi
Pancreatic Unit, Department of Surgical and Gastroenterological Sciences, Policlinico B Roma, Verona University, Verona, Italy
Br J Surg 90:555-9. 2003..Pancreatic metastases from renal cell carcinoma are rare but highly resectable. The aim of this study was to review a series of patients with this condition...
Management of complications after pancreaticoduodenectomy in a high volume centre: results on 150 consecutive patientsC Bassi
Surgical and Gastroenterological Department, Endocrine and Pancreatic Unit, University of Verona, Hospital G B Rossi, Verona, Italy
Dig Surg 18:453-7; discussion 458. 2001..The continued high morbidity of PDs is compensated by the ability to treat complications non-operatively, resulting in a surgical risk that should now be considered medium to low in high volume centres...
Middle segment pancreatectomy: a useful tool in the management of pancreatic neoplasmsClaudio Bassi
Depaerment of Surgery, Policlinico G B Rossi, University of Verona, Piazzale L A Scuro 10, 37134 Verona, Italy
J Gastrointest Surg 11:726-9. 2007..Moreover, it allows the surgeon to preserve pancreatic parenchyma and consequently long term endocrine and exocrine pancreatic function...
Middle segment pancreatectomy: a useful tool in the management of pancreatic neoplasmsClaudio Bassi
Department of Surgery, Chirurgia Generale B, Policlinico GB Rossi, University of Verona, Piazzale L A Scuro 10, Verona, 37134, Italy
J Gastrointest Surg 11:421-4. 2007..Moreover, it allows a surgeon to preserve pancreatic parenchyma and consequently long-term endocrine and exocrine pancreatic function...
Open pancreaticogastrostomy after pancreaticoduodenectomy: a pilot studyClaudio Bassi
Surgical and Gastroenterological Department, Hospital, University of Verona, Verona, Italy
J Gastrointest Surg 10:1072-80. 2006..The mean hospitalization time was 11.1 days (range, 8-25 days). The results obtained in this pilot study appear encouraging and merit further analysis in a randomized comparative trial...
Postoperative pancreatic fistula: an international study group (ISGPF) definitionClaudio Bassi
Surgical and Gastroenterological Department, Hospital G B Rossi, University of Verona, Italy
Surgery 138:8-13. 2005..Our aim was to agree upon an objective and internationally accepted definition to allow comparison of different surgical experiences...
Reconstruction by pancreaticojejunostomy versus pancreaticogastrostomy following pancreatectomy: results of a comparative studyClaudio Bassi
Surgical and Gastroenterological Department, Endocrine and Pancreatic Unit, Hospital G B Rossi, University of Verona, 37134 Verona, Italy
Ann Surg 242:767-71, discussion 771-3. 2005..To compare the results of pancreaticogastrostomy versus pancreaticojejunostomy following pancreaticoduodenectomy in a prospective and randomized setting...
The value of standard serum tumor markers in differentiating mucinous from serous cystic tumors of the pancreas: CEA, Ca 19-9, Ca 125, Ca 15-3Claudio Bassi
Endocrine and Pancreatic Unit, Surgical and Gastroenterological Department, Hospital G B Rossi, University of Verona, Piazzale L A Scuro, Italy
Langenbecks Arch Surg 387:281-5. 2002..Examination of preoperative serum tumor markers may help improve preoperative diagnosis...
Pancreatic fistula rate after pancreatic resection. The importance of definitionsClaudio Bassi
Surgical Science Department, Pancreatic Unit, Hospital G B Rossi, University of Verona, Italy
Dig Surg 21:54-9. 2004....
Management of 100 consecutive cases of pancreatic serous cystadenoma: wait for symptoms and see at imaging or vice versa?Claudio Bassi
Surgical Gastroenterological Department, Endocrine and Pancreatic Unit, Hospital G B Rossi, University of Verona, 37134, Verona, Italy
World J Surg 27:319-23. 2003..This is mainly relevant to the oligocystic forms, which account for about one fourth of all serous tumors observed...
Outcome of open necrosectomy in acute pancreatitisC Bassi
Surgical and Gastroenterological Department, Pancreatic Unit, Verona University, Verona, Italy
Pancreatology 3:128-32. 2003..The aim of this study was to review the most recent literature in order to present an update of open surgical management of infected necrosis...
Natural history of intraductal papillary mucinous neoplasms (IPMN): current evidence and implications for managementClaudio Bassi
Department of Surgery and Gastroenterology, G B Rossi BorgoRoma Hospital, University of Verona, 37134 Verona, Italy
J Gastrointest Surg 12:645-50. 2008..4) After resection of noninvasive IPMNs (branch- and main-duct varieties), recurrence is rare (<8%). (5) After resection of invasive IPMN, recurrence occurs in 50-65% of patients...
IS-741 (Ishihara Sangyo)C Bassi
Surgical and Gastroenterological Department, University of Verona, Hospital GB Rossi, Verona, Italy
Curr Opin Investig Drugs 2:510-2. 2001..Sumitomo is developing the drug in phase II trials for acute pancreatitis 13990261. In an animal model, IS-741 has been shown to prevent pancreatitis-associated lung injury following endotoxemia [337503]...
Acute pancreatitis at the beginning of the 21st century: The state of the artAlfredo F Tonsi
Department of Surgery, G B Rossi Borgo Roma Hospital, University of Verona, 37134 Verona, Italy
World J Gastroenterol 15:2945-59. 2009..Advanced understanding of the pathology, and increased interest in assessment of disease severity are the cornerstones of future management strategies of this complex and heterogeneous disease in the 21st century...
Intraductal papillary mucinous neoplasms (IPMNs): is it time to (sometimes) spare the knife?Claudio Bassi
Department of Surgery, Policlinico GB Rossi, University of Verona, Piazzale LA Scuro, 10, 37134 Verona, Italy
Gut 57:287-9. 2008
Early detection of pancreatic cancer following the diagnosis of chronic pancreatitisG Talamini
Gastroenterological, University of Verona, Italy
Digestion 60:554-61. 1999....
Primary tumour resection in metastatic nonfunctioning pancreatic endocrine carcinomasR Bettini
Department of Surgery, University of Verona, Verona, Italy
Dig Liver Dis 41:49-55. 2009..The role of debulking surgery in metastatic nonfunctioning pancreatic endocrine carcinomas (M-NF-PECs) with resectable primary tumour and unresectable liver metastases is debated...
Clinicopathological features and treatment of intraductal papillary mucinous tumour of the pancreasM Falconi
Department of Surgery, University of Verona, Verona, Italy
Br J Surg 88:376-81. 2001..The surgical strategy in patients with a pancreatic intraductal papillary mucinous tumour (IPMT) is still controversial. In this study the pathological findings in a series of patients were used to rationalize surgical choice...
"Paraduodenal" pancreatitis: results of surgery on 58 consecutives patients from a single institutionL Casetti
Dipartimento di Scienze Chirurgiche, University of Verona, Policlinico GB Rossi, Piazzale LA Scuro, 37134 Verona, Italy
World J Surg 33:2664-9. 2009..The objective of the present study was to investigate the clinical characteristics, therapeutic strategies, and results in 58 patients undergoing pancreatic resection for PP...
Intraductal papillary mucinous tumors of the pancreas. Verona University Pancreatic TeamC Bassi
Department of Surgery Gastroenterology, University Hospital G B Rossi, Verona, Italy
Int J Pancreatol 27:181-93. 2000..Literature is thoroughly reviewed and compared to our own experience...
Role of unlabelled somatostatin analogues in the prevention of complications after elective pancreatic and peripancreatic surgery: a critical reviewM Falconi
Department of Surgery, G B Rossi Hospital, LA Scuro Square, University of Verona, 37134 Verona, Italy
Dig Liver Dis 36:S121-7. 2004..Finally, the selection of the centres that enrol the patients must be considered, since the expertise of each operator or of the team, affects, as an independent variable, both morbidity and mortality...
Prophylaxis for septic complications in acute necrotizing pancreatitisC Bassi
Surgical and Gastroenterological Department, Hospital G.B. Rossi, University of Verona, 37134 Verona, Italy
J Hepatobiliary Pancreat Surg 8:211-5. 2001..Strong consideration should be given to treating patients with severe pancreatitis with broadspectrum antibiotics, selective digestive decontamination, and enteral nutrition...
Prognostic factors at diagnosis and value of WHO classification in a mono-institutional series of 180 non-functioning pancreatic endocrine tumoursR Bettini
Department of Surgical and Gastroenterological Sciences, University of Verona, Verona, Italy
Ann Oncol 19:903-8. 2008..The present study assessed survival, value of World Health Organisation (WHO) classification and prognostic utility of clinicopathological parameters at diagnosis...
Enucleation of pancreatic neoplasmsS Crippa
Department of Surgery, Policlinico GB Rossi, University of Verona, Piazzale L A Scuro 10, 37134 Verona, Italy
Br J Surg 94:1254-9. 2007..The aim of this study was to evaluate postoperative and long-term oncological and functional results after pancreatic enucleation...
Infection prevention in necrotizing pancreatitis: an old challenge with new perspectivesG Butturini
Pancreatic Unit Surgical Department, Verona University, Verona, Italy
J Hosp Infect 49:4-8. 2001..The aim of this paper is to present an up-to-date assessment of current challenges in the management of necrotizing pancreatitis in order to prevent infection...
Role of octreotide in the treatment of external pancreatic pure fistulas: a single-institution prospective experienceC Bassi
Surgical and Gastroenterological Department, University of Verona, Policlinico G B Rossi, I 37134 Verona, Italy
Langenbecks Arch Surg 385:10-3. 2000..Octreotide was studied in the treatment of pure external pancreatic fistulas...
Alcohol intake, cigarette smoking, and body mass index in patients with alcohol-associated pancreatitisG Talamini
Gastroenterological and Surgical Department, University of Verona, Italy
J Clin Gastroenterol 31:314-7. 2000..07-1.33; p < 0.00015) in favor of acute alcoholic pancreatitis. In male patients, from an epidemiologic standpoint, only smoking habits and BMI are significant differences at clinical onset between the two types of pancreatitis...
Alcohol, smoking and papillomavirus infection as risk factors for esophageal squamous-cell papilloma and esophageal squamous-cell carcinoma in ItalyG Talamini
Digestive Endoscopy Service, University of Verona, Verona, Italy
Int J Cancer 86:874-8. 2000..Environmental factors, such as alcohol and smoking, appear to play a decisive role in esophageal carcinogenesis in northern Italy...
Previous cholecystectomy, gastrectomy, and diabetes mellitus are not crucial risk factors for pancreatic cancer in patients with chronic pancreatitisG Talamini
Gastroenterological and Surgical Department, University of Verona, 37134 Verona, Italy
Pancreas 23:364-7. 2001..In the general population, cholecystectomy, diabetes, and chronic pancreatitis seem to be associated with an increased risk of developing pancreatic cancer...
Influence of surgical resection and post-operative complications on survival following adjuvant treatment for pancreatic cancer in the ESPAC-1 randomized controlled trialC Bassi
Surgical Department, Endocrine and Pancreatic Unit, University of Verona, Verona, Italy
Dig Surg 22:353-63. 2005..Post-operative complications did not adversely affect the survival benefit from adjuvant chemotherapy...
Pancreatic cystic tumours: when to resect, when to observeR Salvia
Department of Surgery, Chirurgia Generale B, Policlinico GB Rossi, University of Verona, Verona, Italy
Eur Rev Med Pharmacol Sci 14:395-406. 2010..In recent years there has been an increase in the diagnosis of cystic tumors of the pancreas. In this setting, difficult diagnostic problems and different therapeutic management can be proposed...
Middle pancreatectomy: indications, short- and long-term operative outcomesStefano Crippa
Department of Surgery, Policlinico GB Rossi, University of Verona, Verona, Italy
Ann Surg 246:69-76. 2007..To evaluate the indications, perioperative, and long-term outcomes of a large cohort of patients who underwent middle pancreatectomy (MP)...
Resectable pancreatic cancer: who really benefits from resection?Giuliano Barugola
Chirurgia Generale B, Department of Surgery, University of Verona, Verona, Italy
Ann Surg Oncol 16:3316-22. 2009..The 1-year disease-related mortality after resection for pancreatic cancer is approximately 30%. This study examined potential preoperative parameters that would help avoid unnecessary surgery...
Role of fistulography in evaluating pancreatic fistula after pancreaticoduodenectomyN Faccioli
Department of Radiology, G B Rossi Hospital, University of Verona, Verona, Italy
Br J Radiol 85:219-24. 2012..To evaluate the usefulness of fistulography as a diagnostic and management tool for clinically suspected pancreatic fistulas (PF) after pancreaticoduodenectomy (PD)...
Feasibility and safety of radiofrequency ablation for locally advanced pancreatic cancerR Girelli
Hepatopancreatobiliary Unit, University of Verona, Verona, Italy
Br J Surg 97:220-5. 2010..Radiofrequency ablation (RFA) may be a valuable treatment option for locally advanced pancreatic cancer. The present study examined its feasibility and safety...
In vivo octreotide administration acutely reduces exocrine granule size in the human pancreasM Falconi
Departments of Surgical and Gastroenterological Sciences, Section of Anatomy and Histology, University of Verona, Strada Le Grazie, I-37134 Verona, Italy
Pancreatology 1:30-5. 2001..Such an effect is not maintained over multiple administrations of the somatostatin analogue. Possible explanations for this latter finding are discussed...
Lactobacillus plantarum reduces infection of pancreatic necrosis in experimental acute pancreatitisG Mangiante
Department of Surgery, University of Verona, Italy
Dig Surg 18:47-50. 2001..CONCLUSIONS: Lp 299v is effective in reducing microbial translocation in experimental pancreatitis. Treatment with probiotic bacteria seems to be a promising alternative to antibiotic therapy...
Evaluation of lanreotide effects on human exocrine pancreatic secretion after a single dose: preliminary studyM Falconi
Endocrine Surgery, Surgical Department, Policlinico Borgo Roma, Verona, Italy
Dig Liver Dis 34:127-32. 2002..Total parenteral nutrition and somatostatin or analogues represent a consolidated therapeutic approach for external fistulas, a frequent complication of major pancreatic surgery...
Gemcitabine and continuous infusion of 5-fluorouracil in locally advanced and metastatic pancreatic cancer: a phase I-II studyC Oliani
Department of Medical Oncology, Gastroenterological Sciences, University of Verona, Italy
Anticancer Res 24:2107-12. 2004....
Carcinoma of pancreatic body and tail: are there improvements in diagnosis and treatment modalities over the past decade?M Falconi
Department of Surgery, University of Verona, Verona, Italy
Dig Liver Dis 35:421-7. 2003..The aim of the present study is to assess whether or not there has been improvement in the therapeutic strategy for body-tail pancreatic carcinoma over the past decade...
Amylase value in drains after pancreatic resection as predictive factor of postoperative pancreatic fistula: results of a prospective study in 137 patientsEnrico Molinari
Department of Surgery and Gastroenterology, University of Verona, Italy
Ann Surg 246:281-7. 2007..The correlation of the amylase value in drains (AVD) with the development of pancreatic fistula (PF) is still unclear...
Antibacterial and mezlocillin-enhancing activity of pure human pancreatic fluidC Bassi
Surgical Department, University of Verona, Borgo Roma Hospital, Italy
Int J Pancreatol 10:293-7. 1991..These enhancing characteristics might make the commonly used doses sufficient for prophylactic purposes...
Autoimmune pancreatitis: possibilities of CT characterizationC Procacci
Department of Radiology, University of Verona Medical School, Policlinico G B Rossi, Verona, Italy
Pancreatology 1:246-53. 2001..This type of pancreatitis should be differentiated from other pancreatic diseases, since appropriate therapy is effective and morphological changes and pancreatic function can recover to normal levels...
Management of digestive tract fistulas. A reviewM Falconi
Servizio di Endocrinochirurgia, Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Universita degli Studi di Verona, Italia
Digestion 60:51-8. 1999..The amount of octreotide administered ranges from 300 to 600 micrograms/day in 3 or 4 daily doses...
Invasive intraductal papillary mucinous carcinomas of the pancreas: predictors of survival and the role of lymph node ratioStefano Partelli
Department of Surgery, University of Verona, Verona, Italy
Ann Surg 251:477-82. 2010..Lymph node metastases are an important prognostic factor for patients with invasive intraductal papillary carcinoma (I-IPMC), but the role of lymph node ratio (LNR) in predicting survival after surgery for I-IPMC is unknown...
Piperacillin-tazobactam penetration into human pancreatic juiceElisa Bertazzoni Minelli
Department of Medicine and Public Health, Pharmacology Section, University of Verona, Verona, Italy
Antimicrob Agents Chemother 52:4149-52. 2008..5 to 6 h) according to bacterial susceptibility and patients' characteristics. Piperacillin and tazobactam showed superimposable pharmacokinetics in both serum and pancreatic juice...
Long-term results of Frey's procedure for chronic pancreatitis: a longitudinal prospective study on 40 patientsMassimo Falconi
Department of Surgical, University of Verona, Verona, Italy
J Gastrointest Surg 10:504-10. 2006....
Smoking cessation at the clinical onset of chronic pancreatitis and risk of pancreatic calcificationsGiorgio Talamini
Gastroenterology and Endoscopy Unit, University of Verona, Verona, Italy
Pancreas 35:320-6. 2007..The aim of this study was to know whether smoking cessation modifies the course of the disease...
Intraductal papillary mucinous neoplasms and chronic pancreatitisGiorgio Talamini
Gastroenterology and Endoscopy Unit, University of Verona, Verona, Italy
Pancreatology 6:626-34. 2006..Intraductal papillary mucinous neoplasms (IPMNs) may present with clinical and radiological pictures resembling those of chronic pancreatitis (CP)...
The determinant factors of recurrence following resection for ductal pancreatic cancerGiuliano Barugola
B Unit, Department of Surgery, University of Verona Verona, Italy
JOP 8:132-40. 2007..The aim of this review is to point out the major factors most commonly identified as determinants of both recurrence and relapse...
Prognostic relevance of lymph node ratio and number of resected nodes after curative resection of ampulla of Vater carcinomaMassimo Falconi
Chirurgia Generale B Pancreas Unit, Department of Surgery, University of Verona, Policlinico GB Rossi, Piazzale LA Scuro, 37134 Verona, Italy
Ann Surg Oncol 15:3178-86. 2008..No study has investigated the significance of the ratio between metastatic and resected/examined lymph nodes (LNR) in patients with AVC...
Contrast-enhanced ultrasonography of the pancreasNiccolo Faccioli
Department of Radiology, Policlinico G B Rossi, University of Verona, Verona, Italy
Pancreatology 9:560-6. 2009..This article reviews the clinical and surgical applications of CEUS in different pancreatic diseases and in their management...
Motility analysis of pancreatic adenocarcinoma cells reveals a role for the atypical zeta isoform of protein kinase C in cancer cell movementCarlo Laudanna
Department of Pathology, University of Verona, Italy
Lab Invest 83:1155-63. 2003..These data suggest that the disregulation of the function of atypical zeta PKC might be involved in the acquisition of an invasive and metastatic phenotype in pancreatic adenocarcinoma cells...
Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: results of a prospective randomized trialClaudio Bassi
Surgical and Gastroenterological Department, Endocrine and Pancreatic Unit, Hospital G.B. Rossi University of Verona, Piazzale L.A. Scuro, 37134 Verona, Italy
Surgery 134:766-71. 2003..Two patients (2%) required reoperation; the postoperative mortality rate was 1%. CONCLUSION: The 2 methods that were studied revealed no significant difference the rate of complications...
Radiofrequency ablation of locally advanced pancreatic adenocarcinoma: an overviewMirko D'Onofrio
Department of Radiology, University Hospital G B Rossi, University of Verona, Piazzale L A Scuro 10, Verona 37134, Italy
World J Gastroenterol 16:3478-83. 2010..Nowadays, only a few studies assess the feasibility of the procedure. The present paper is an overview of RFA for pancreatic adenocarcinoma...
Main-duct intraductal papillary mucinous neoplasms of the pancreas: clinical predictors of malignancy and long-term survival following resectionRoberto Salvia
Department of Surgery, University of Verona, Verona, Italy
Ann Surg 239:678-85; discussion 685-7. 2004..These findings support both the concept of progression of benign IPMNs to invasive cancer and an aggressive policy of resection at diagnosis...
Parenchyma-preserving resections for small nonfunctioning pancreatic endocrine tumorsMassimo Falconi
Chirurgia Generale B Pancreas Unit, Department of Surgery, University of Verona, Policlinico GB Rossi, Verona, Italy
Ann Surg Oncol 17:1621-7. 2010..The aim of this study was to evaluate perioperative and long-term outcomes after PPRs for NF-PETs...
Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in pancreatic cancerLuigina Franco
Department of Medicine and Public Health, Section of Pharmacology, University of Verona, Piazzale L A Scuro, 37134 Verona, Italy
Prostaglandins Other Lipid Mediat 73:51-8. 2004..These observations suggest that COX-2 and iNOS may be a target for prevention or treatment of pancreatic carcinomas...
Intraductal papillary mucinous neoplasms of the pancreas with multifocal involvement of branch ductsRoberto Salvia
Department of Surgery, University of Verona, Verona, Italy
Am J Surg 198:709-14. 2009..The appropriate management of patients with branch-duct intraductal papillary mucinous neoplasm (BD-IPMN) with multiple involvements of branch ducts (multifocal BD-IPMN) remains challenging...
Middle-preserving pancreatectomy for multicentric body-sparing lesions of the pancreasStefano Partelli
Department of Surgery, University of Verona, Verona, Italy
Am J Surg 198:e49-53. 2009..We sought to analyze a parenchyma-sparing surgical technique consisting of a middle-preserving pancreatectomy (MPP) evaluating feasibility, safety, and oncological and functional outcomes...
Intraductal papillary mucinous tumors of the pancreas. Surgical treatment: at what point should we stop?Roberto Salvia
Department of Surgery, University of Verona, Verona, Italy
JOP 6:112-7. 2005....
The role of laparoscopy in advanced pancreatic cancer diagnosisGiovanni Butturini
Surgical and Gastroenterological Department, University of Verona, Policlinico GB Rossi, Verona, Italy
Dig Surg 24:33-7. 2007..Whenever percutaneous and endoscopic ultrasound-guided pancreatic fine needle aspiration (FNA) fails to obtain a diagnostic specimen, a laparoscopic approach may be employed...
Italian consensus guidelines for chronic pancreatitisLuca Frulloni
Department of Medicine, University of Verona, Verona, Italy
Dig Liver Dis 42:S381-406. 2010....
Cystic "feminine" pancreatic neoplasms in men. Do any clinical alterations correlate with these uncommon entities?P Regi
Department of General Surgery, Pancreas Institute, University of Verona, Verona, Italy
Int J Surg 11:157-60. 2013..This trial aims to investigate the possible association between HRPTs development in males and phenotypic and sex hormone alterations...
Prospective multicentre survey on acute pancreatitis in Italy (ProInf-AISP): results on 1005 patientsG Cavallini
Department of Surgical and Gastroenterological Sciences, University of Verona, Piazzale LA Scuro 10, 37134 Verona, Italy
Dig Liver Dis 36:205-11. 2004..The treatment of the disease is not optimal and, on the basis of these data, needs to be standardised. Despite this, the overall mortality rate is low (5%)...
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4P S Moore
Department of Pathology, University of Verona, Italy
Virchows Arch 439:798-802. 2001....
Obstructive chronic pancreatitis and/or intraductal papillary mucinous neoplasms (IPMNs): a 21-year long case reportMohammed Abu-Hilal
Department of Surgical and Gastroenterological Sciences, Policlinico GB Rossi, University of Verona, Verona, Italy
JOP 7:218-21. 2006..Intraductal papillary mucinous neoplasms of the pancreas (IPMNs), usually present with a picture of chronic pancreatitis and must be considered within the differential diagnosis of this condition...
Branch-duct intraductal papillary mucinous neoplasms of the pancreas: to operate or not to operate?Roberto Salvia
Department of Surgery, University of Verona, Policlinico GB Rossi, Piazzale LA Scuro 10, 37134 Verona, Italy
Gut 56:1086-90. 2007..Branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs) of the pancreas are reported to be less aggressive than the main-duct type. Hence, less aggressive treatment has been proposed for the former...
Complications after pancreaticoduodenectomy: the problem of current definitionsGiovanni Butturini
Surgical and Gastroenterological Department, University of Verona, Policlinico GB Rossi, Piazzale LA Scuro 10, 37134, Verona, Italy
J Hepatobiliary Pancreat Surg 13:207-11. 2006..The aim of this article is to review the current controversial definitions and to suggest a new clinical-based approach to the problem of the feasibility and reliability of the definitions themselves...
Clinical and biological behavior of pancreatic solid pseudopapillary tumors: report on 31 consecutive patientsRoberto Salvia
Department of Surgery, University of Verona, GB Rossi Hospital, Verona, Italy
J Surg Oncol 95:304-10. 2007..Solid pseudopapillary tumors (SPTs) represent one of the most uncommon histotypes of all exocrine pancreatic neoplasms...
Substance P and neprilysin in chronic pancreatitisG Mascetta
Department of Surgery, IRCCS, Hospital Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
Eur Surg Res 48:131-8. 2012..We aimed to analyze substance P (SP) and neprilysin (NEP), the membrane metallopeptidase that degrades SP, in chronic pancreatitis (CP)...
ESPEN Guidelines on Parenteral Nutrition: pancreasL Gianotti
Department of Surgery, Milano Bicocca University, San Gerardo Hospital, Monza, Italy
Clin Nutr 28:428-35. 2009..In chronic pancreatitis PN may, on rare occasions, be indicated in patients with gastric outlet obstruction secondary to duodenal stenosis or those with complex fistulation, and in occasional malnourished patients prior to surgery...
Review of the clinical, histological, and molecular aspects of pancreatic endocrine neoplasmsA A Gumbs
Department of Surgery, University of Verona, Verona, Italy
J Surg Oncol 81:45-53; discussion 54. 2002....
Overexpression of the Sm-like proto-oncogene in primary and metastatic pancreatic endocrine tumorsAndrew A Gumbs
Department of Surgical and Gastroenterological Sciences, University of Verona. Verona, Italy
JOP 3:109-15. 2002..CONCLUSIONS: Our results indicate that the cancer associated Sm-like mRNA gene may also play a role in the tumorigenesis of pancreatic endocrine tumors...
Gene expression profiling after treatment with the histone deacetylase inhibitor trichostatin A reveals altered expression of both pro- and anti-apoptotic genes in pancreatic adenocarcinoma cellsPatrick S Moore
Dipartimento di Patologia, , Strada Le Grazie, 8, 37134 Verona, Italy
Biochim Biophys Acta 1693:167-76. 2004..This result was confirmed in eight additional pancreatic cancer cell lines after treatment with TSA, suggesting that this event may be a strong determinant for the induction of apoptosis by TSA...
Trichostatin A, an inhibitor of histone deacetylases, strongly suppresses growth of pancreatic adenocarcinoma cellsMassimo Donadelli
Department of Neurological and Vision Sciences, , Verona, Italy
Mol Carcinog 38:59-69. 2003..These findings suggest that inhibitors of HDAC may represent a novel therapeutic strategy for treatment of pancreatic cancer...
Preemptive ketamine during general anesthesia for postoperative analgesia in patients undergoing laparoscopic cholecystectomyC Launo
Section of Anesthesia and Intensive Care, Department of Surgery, Anesthesia and Transplants (DISCAT, School of Anesthesia and Intensive Care, University of Genoa, Genoa, Italy
Minerva Anestesiol 70:727-34; 734-8. 2004....
Infections in pancreatic inflammatory disease: clinical trials for antibiotic prophylaxisC Bassi
Surgical and Gastroenterological Department-Endocrine and Pancreatic Unit, Borgo Roma Hospital G.B. Rossi, University of Verona, I-37134 Verona, Italy
Pancreatology 1:210-2. 2001..Here we review the most important controlled clinical experiences reported up to now...
Mucin-producing neoplasms of the pancreas: an analysis of distinguishing clinical and epidemiologic characteristicsStefano Crippa
Department of Surgery, Policlinico GB Rossi, University of Verona, Verona, Italy
Clin Gastroenterol Hepatol 8:213-9. 2010..MCNs and branch-duct IPMNs are frequently confused; it is unclear whether main-duct, combined, and branch-duct IPMNs are a different spectrum of the same disease. We evaluated their clinical and epidemiologic characteristics...
Mucinous cystic neoplasm of the pancreas is not an aggressive entity: lessons from 163 resected patientsStefano Crippa
Department of Surgery, University of Verona, Verona, Italy
Ann Surg 247:571-9. 2008..We evaluated the clinicopathologic characteristics, prevalence of cancer, and prognosis of a large series of well-characterized MCNs in 2 tertiary centers...
Pancreatic fistula: definition and current problemsGiovanni Butturini
Surgical and Gastroenterological Department, Verona University, Verona, Italy
J Hepatobiliary Pancreat Surg 15:247-51. 2008..The use of somatostatin analogues is still matter of controversy. Conservative management of POPF is usually effective, but in patients with deteriorating clinical status with evidence of sepsis, surgical management is needed...
What preoperative assessment is necessary for insulinomas? Calculating the degree of waste: analysis of 29 casesMassimo Falconi
Surgical Department, University of Verona, Verona
Chir Ital 54:597-604. 2002..Surgery with the help of IOUS, preceded by only one pre-op diagnostic imaging technique represents the best approach for establishing the diagnosis of and treating insulinomas...
Prophylactic pylorus-preserving gastric transposition in unresectable carcinoma of the pancreatic headMassimo Falconi
Department of Surgery, University of Verona, Piazzale L. A. Scuro, 37134 Verona, Italy
Am J Surg 187:564-6. 2004....
A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancerJohn P Neoptolemos
Department of Surgery, Liverpool University, Liverpool, United Kingdom
N Engl J Med 350:1200-10. 2004..CONCLUSIONS: Adjuvant chemotherapy has a significant survival benefit in patients with resected pancreatic cancer, whereas adjuvant chemoradiotherapy has a deleterious effect on survival...
Symptoms and quality of life in chronic pancreatitis assessed by structured interview and the EORTC QLQ-C30 and QLQ-PAN26Deborah Fitzsimmons
School of Nursing and Midwifery, University of Southampton, Southampton, United Kingdom
Am J Gastroenterol 100:918-26. 2005..Patients' QoL is adversely affected by the fear of future health problems, difficulty sleeping, and fatigue...
Laparoscopic pancreatic resection: results of a multicenter European study of 127 patientsJean-Yves Mabrut
Saint-Luc University Hospital, Brussels, Belgium
Surgery 137:597-605. 2005..CONCLUSIONS: LPR is feasible and safe in selected patients with presumed benign and distal pancreatic tumors. The management of the pancreatic stump remains a challenge. The role of LPR for pancreatic malignancies remains controversial...
Identification of proteins released by pancreatic cancer cells by multidimensional protein identification technology: a strategy for identification of novel cancer markersPierluigi Mauri
Istituto Tecnologie Biomediche ITB CNR, Segrate, Milano, Italy
FASEB J 19:1125-7. 2005..Our finding that pancreatic cancer cells secrete a series of proteoglycans, including versican, perlecan, syndecan 1 and 4, challenges the common view that fibroblasts of tumor stroma are the sole source of these molecules...
Pancreatic anastomotic leakage after pancreaticoduodenectomy in 1,507 patients: a report from the Pancreatic Anastomotic Leak Study GroupKaye M Reid Lombardo
Division of Gastroenterologic and General Surgery, Mayo Clinic, Rochester, MN, USA
J Gastrointest Surg 11:1451-8; discussion 1459. 2007..The ISGPF was able to capture more patients with clinically relevant leaks than Sarr's criteria; however, the ability to detect a leak by drain data alone is imperfect...
Laparoscopic distal pancreatectomy: results on a consecutive series of 58 patientsGianluigi Melotti
Surgical Department, New Hospital Sant Agostino Estense Baggiovara Modena, Italy
Ann Surg 246:77-82. 2007..To describe the clinical characteristics, indications, technical procedures, and outcome of a consecutive series of laparoscopic distal pancreatic resections performed by the same surgical team...
Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS)Moritz N Wente
Department of General Surgery, University of Heidelberg, Im Neuenheimer Feld 110, Heidelberg, Germany
Surgery 142:761-8. 2007..Several surgical centers use a different definition of DGE. Hence, a valid comparison of different study reports and operative techniques is not possible...
Branch-duct intraductal papillary mucinous neoplasms: observations in 145 patients who underwent resectionJ Ruben Rodriguez
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Gastroenterology 133:72-9; quiz 309-10. 2007..This study describes the combined experience of 2 tertiary centers with branch-duct IPMNs aiming to validate these recommendations...
Prognostic factors in patients with advanced pancreatic adenocarcinoma treated with intra-arterial chemotherapyAndrea Mambrini
Department of Oncology, Massa Carrara City Hospital, Massa Carrara, Italy
Pancreas 36:56-60. 2008..The aim of this study is to identify the prognostic factors of a large group of patients with pancreatic cancer who underwent the same regimen of intra-arterial chemotherapy...
Influence of resection margins and treatment on survival in patients with pancreatic cancer: meta-analysis of randomized controlled trialsGiovanni Butturini
Division of Surgery and Oncology, School of Cancer Studies, Royal Liverpool University Hospital, 5th Floor, UCD Bldg, Daulby St, Liverpool L69 3GA, England
Arch Surg 143:75-83; discussion 83. 2008..To assess the influence of resection margins and adjuvant chemoradiotherapy or chemotherapy on survival for patients with pancreatic cancer by meta-analysis of individual data from randomized controlled trials...
Radiotherapy and chemotherapy in pancreatic cancer. Topical issues and future perspectivesGiovanni Boz
Department of Radiotherapy, CRO, Aviano (PN, Italy
JOP 7:122-30. 2006
SEL1L expression in pancreatic adenocarcinoma parallels SMAD4 expression and delays tumor growth in vitro and in vivoMonica Cattaneo
1Institute for Biomedical Technologies National Research Council, Milano, Italy
Oncogene 22:6359-68. 2003..Moreover, our data provide evidence that SEL1L has an impact on the expression of genes involved in regulation of cellular growth, possibly through the TGF-beta signaling pathway...
[Integrated project for the translational research on pancreatic ductal carcinoma]Stefano Marcucci
UO di Endocrinochirurgia, Dipartimento di Scienze Chirurgiche e Gastroenterologiche,
Chir Ital 54:845-54. 2002..This model is also expected to be an effective approach for the evaluation of experimental chemotherapeutic schedules and new gene therapy assessment...
IAP Guidelines for the Surgical Management of Acute PancreatitisWaldemar Uhl
Department of General Surgery, University of Heidelberg, Germany
Pancreatology 2:565-73. 2002..There is however a theoretical risk of introducing infection into sterile pancreatic necrosis. These guidelines should now form the basis for audit studies in order to determine the quality of patient care delivery...
Maldi-TOF analysis of portal sera of pancreatic cancer patients: identification of diabetogenic and antidiabetogenic peptidesAnna Valerio
Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Clin Chim Acta 343:119-27. 2004..CONCLUSIONS: Unlike liver GAPDH, NO appears to be involved in PC associated DM. In portal sera, the absence, rather than the presence, of specific fragments, appears to be correlated with the development of DM...
Early assessment of pancreatic infections and overall prognosis in severe acute pancreatitis by procalcitonin (PCT): a prospective international multicenter studyBettina M Rau
Department of General, Visceral, and Vascular Surgery, University of the Saarland, Kirrberger Strasse, 66421 Homburg Saar, Germany
Ann Surg 245:745-54. 2007..We investigated the value of Procalcitonin (PCT) for identifying patients at risk to develop pancreatic infections in severe AP...
