L Barzon


Affiliation: University of Padova
Country: Italy


  1. Barzon L, Squarzon L, Militello V, Trevisan M, Porzionato A, Macchi V, et al. WU and KI polyomaviruses in the brains of HIV-positive patients with and without progressive multifocal leukoencephalopathy. J Infect Dis. 2009;200:1755-8 pubmed publisher
    ..No specific histopathological findings were found to be associated with the presence of WUPyV and KIPyV...
  2. Barzon L, Papa A, Pacenti M, Franchin E, Lavezzo E, Squarzon L, et al. Genome sequencing of West Nile Virus from human cases in Greece, 2012. Viruses. 2013;5:2311-9 pubmed publisher
    ..In conclusion, this study characterized for the first time a WNV full genome from a patient with WNND from Greece, demonstrated the persistence of the Nea Santa strain, and suggested that the virus might have locally evolved. ..
  3. Barzon L. Ongoing and emerging arbovirus threats in Europe. J Clin Virol. 2018;107:38-47 pubmed publisher
    ..The identification of emerging outbreaks is however challenging and requires a high degree of awareness and laboratory capacity, especially for the most neglected but potentially threatening pathogens. ..
  4. Barzon L, Masi G, Pacenti M, Trevisan M, Fallo F, Remo A, et al. Expression of aromatase and estrogen receptors in human adrenocortical tumors. Virchows Arch. 2008;452:181-91 pubmed
    ..This study opens new perspectives on the potential use of antiestrogens and aromatase inhibitors as therapeutic agents against ACC. ..
  5. Barzon L, Trevisan M, Masi G, Pacenti M, Sinigaglia A, Macchi V, et al. Detection of polyomaviruses and herpesviruses in human adrenal tumors. Oncogene. 2008;27:857-64 pubmed
    ..On the other hand, these viruses could also contribute to adrenal cell proliferation and tumorigenesis. ..
  6. Barzon L, Lavezzo E, Costanzi G, Franchin E, Toppo S, Palu G. Next-generation sequencing technologies in diagnostic virology. J Clin Virol. 2013;58:346-50 pubmed publisher
    ..We provide here some suggestions for virologists who are planning to implement a NGS platform in their clinical laboratory and an overview on the potential applications of these technologies in diagnostic virology. ..
  7. Ravagnan S, Montarsi F, Cazzin S, Porcellato E, Russo F, Palei M, et al. First report outside Eastern Europe of West Nile virus lineage 2 related to the Volgograd 2007 strain, northeastern Italy, 2014. Parasit Vectors. 2015;8:418 pubmed publisher
    ..This strain may pose a new threat to animal and human health in Italy. ..
  8. Barzon L, Papa A, Lavezzo E, Franchin E, Pacenti M, Sinigaglia A, et al. Phylogenetic characterization of Central/Southern European lineage 2 West Nile virus: analysis of human outbreaks in Italy and Greece, 2013-2014. Clin Microbiol Infect. 2015;21:1122.e1-10 pubmed publisher
    ..In conclusion, the results of this study provide further information on WNV lineage 2 transmission dynamics in Europe, and emphasize the need for WNV surveillance activities to monitor viral evolution and diversity. ..
  9. Trevisan M, Sinigaglia A, Desole G, Berto A, Pacenti M, Palù G, et al. Modeling Viral Infectious Diseases and Development of Antiviral Therapies Using Human Induced Pluripotent Stem Cell-Derived Systems. Viruses. 2015;7:3835-56 pubmed publisher

More Information


  1. Peta E, Cappellesso R, Masi G, Sinigaglia A, Trevisan M, Grassi A, et al. Down-regulation of microRNA-146a is associated with high-risk human papillomavirus infection and epidermal growth factor receptor overexpression in penile squamous cell carcinoma. Hum Pathol. 2017;61:33-40 pubmed publisher
    ..The results of this study indicate that down-regulation of miR-146a may represent another mechanism of EGFR overexpression in PSCCs, which can be mediated by high-risk HPV E6 in HPV-related tumors. ..
  2. Lavezzo E, Masi G, Toppo S, Franchin E, Gazzola V, Sinigaglia A, et al. Characterization of Intra-Type Variants of Oncogenic Human Papillomaviruses by Next-Generation Deep Sequencing of the E6/E7 Region. Viruses. 2016;8:79 pubmed publisher
  3. Barzon L, Trevisan M, Sinigaglia A, Lavezzo E, Palu G. Zika virus: from pathogenesis to disease control. FEMS Microbiol Lett. 2016;363: pubmed
    ..These animal models have been used to evaluate candidate vaccines and promising results have been obtained. ..
  4. Trevisan M, Desole G, Costanzi G, Lavezzo E, Palu G, Barzon L. Reprogramming Methods Do Not Affect Gene Expression Profile of Human Induced Pluripotent Stem Cells. Int J Mol Sci. 2017;18: pubmed publisher
    ..In conclusion, the use of different reprogramming methods is equivalent and does not affect gene expression profile of the derived human iPSCs. ..
  5. Peta E, Sinigaglia A, Masi G, Di Camillo B, Grassi A, Trevisan M, et al. HPV16 E6 and E7 upregulate the histone lysine demethylase KDM2B through the c-MYC/miR-146a-5p axys. Oncogene. 2018;37:1654-1668 pubmed publisher
    ..E6 and, less efficiently, E7 of high-risk HPV16 up-regulated KDM2B expression in human keratinocytes through a pathway involving overexpression of c-MYC, which in turn downregulated miR-146a-5p. ..
  6. Barzon L, Militello V, Pagni S, Palu G. Comparison of INNO-LiPA genotyping extra and hybrid capture 2 assays for detection of carcinogenic human papillomavirus genotypes. J Clin Virol. 2012;55:256-61 pubmed publisher
    ..A good agreement was observed between HC2 and SPF10-LiPA for carcinogenic HPV type detection, that supports further evaluation of the clinical performance of the new version of SPF10-LiPA in cervical cancer screening protocols. ..
  7. Barzon L, Pacenti M, Palu G. West Nile virus and kidney disease. Expert Rev Anti Infect Ther. 2013;11:479-87 pubmed publisher
  8. Barzon L, Pacenti M, Franchin E, Squarzon L, Lavezzo E, Cattai M, et al. The complex epidemiological scenario of West Nile virus in Italy. Int J Environ Res Public Health. 2013;10:4669-89 pubmed publisher
    ..In addition, different strains of both WNV lineage 1 and lineage 2 have been identified, even co-circulating in the same area. ..
  9. Barzon L, Pacenti M, Franchin E, Squarzon L, Lavezzo E, Toppo S, et al. Novel West Nile virus lineage 1a full genome sequences from human cases of infection in north-eastern Italy, 2011. Clin Microbiol Infect. 2012;18:E541-4 pubmed publisher
    ..The presence of different WNV strains in a relatively small geographical area is a novel finding with unpredictable impact on human disease that requires further investigation...
  10. Barzon L, Pacenti M, Franchin E, Pagni S, Martello T, Cattai M, et al. Excretion of West Nile virus in urine during acute infection. J Infect Dis. 2013;208:1086-92 pubmed publisher
    ..2%]) in blood donors in whom WNV infection was identified by WNV nucleic acid amplification testing. Infectious virus was isolated from the urine of a patient with neuroinvasive disease and a high WNV RNA load in urine. ..
  11. Barzon L, Pacenti M, Masi G, Stefani A, Fincati K, Palu G. Loss of growth hormone secretagogue receptor 1a and overexpression of type 1b receptor transcripts in human adrenocortical tumors. Oncology. 2005;68:414-21 pubmed
    ..In this regard, ghrelin inhibits cell proliferation and modulates GHS-R expression in ACC cells in vitro. ..