Maria Teresa Bardella
Affiliation: University of Milan
- Motility disorders in patients with celiac diseaseLuca Elli
U O of Gastroenterology, University of Milan, Italy
Scand J Gastroenterol 40:743-9. 2005
- Gluten intolerance: gender- and age-related differences in symptomsMaria Teresa Bardella
Chair of Gastroenterology, University of Milan, Ospedale Maggiore di Milano, IRCCS, Italy
Scand J Gastroenterol 40:15-9. 2005..Women seem to be more frequently affected although data on sex differences are poor. In this study the prevalence of different clinical pictures according to sex and age is analysed in a large series of patients...
- Autoimmune disorders in patients affected by celiac sprue and inflammatory bowel diseaseMaria Teresa Bardella
Centre for Prevention and Diagnosis of Celiac Disease, Fondazione IRCCS Ospedale Maggiore Policlinico, University of Milan, Italy
Ann Med 41:139-43. 2009..Although clinically different, celiac sprue and inflammatory bowel disease are characterized by chronic intestinal inflammation and associated extraintestinal manifestations...
- Silent celiac disease is frequent in the siblings of newly diagnosed celiac patientsMaria Teresa Bardella
Centre for Prevention and Diagnosis of Celiac Disease, Foundation IRCCS Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena and Chair of Gastroenterology, University of Milan, Milan, Italy
Digestion 75:182-7. 2007..This prospective study evaluates the prevalence of celiac disease in the asymptomatic siblings of celiac patients...
- Long-term remission in patients with dermatitis herpetiformis on a normal dietM T Bardella
Cattedra di Gastroenterologia, Dipartimento di Scienze Mediche IRCCS Ospedale Maggiore, Universita degli Studi di Milano, Milano, Italy
Br J Dermatol 149:968-71. 2003..A life-long gluten-free diet is the treatment of choice for dermatitis herpetiformis, which is considered to be coeliac disease of the skin...
- Searching for coeliac disease in patients with non-alcoholic fatty liver diseaseM T Bardella
Department Medical Sciences, IRCCS Ospedale Maggiore Policlinico di Milano, University of Milan, Via F Sforza, 35, 20122 Milan, Italy
Dig Liver Dis 36:333-6. 2004..Conflicting data have been reported on the prevalence of coeliac disease in non-alcoholic steatohepatitis...
- Serological markers for coeliac disease: is it time to change?M T Bardella
Dept Gastroenterology, University of Milan, IRCCS Ospedale Maggiore, Italy
Dig Liver Dis 33:426-31. 2001..The recent finding that tissue transglutaminase is the main auto-antigen of anti-endomysium has led to the discovery of anti-tissue transglutaminase antibodies...
- Helicobacter pylori prevalence in patients with diabetes and its relationship to dyspeptic symptomsM Quatrini
Cattedra di Gastroenterologia Istituto di Scienze Mediche, IRCCS Ospedale Maggiore, Milano, Italy
J Clin Gastroenterol 32:215-7. 2001..pylori infection, esophagitis, and peptic ulcers found in our patients with diabetes (with or without dyspepsia) suggests that this population should be considered "at risk" for H. pylori infection and suitable candidates for treatment...
- Body composition and dietary intakes in adult celiac disease patients consuming a strict gluten-free dietM T Bardella
Cattedra di Gastroenterologia, Istituto di Scienze Mediche, IRCCS Ospedale Maggiore and Clinica Pediatrica II, Universita degli Studi, Milan, Italy
Am J Clin Nutr 72:937-9. 2000..Celiac disease responds to dietary gluten withdrawal, but data on the long-term effects of gluten-free diets are discordant...
- Alopecia areata and coeliac disease: no effect of a gluten-free diet on hair growthM T Bardella
Istituto di Scienze Mediche, IRCCS Ospedale Maggiore, Universita di Milano, Italia
Dermatology 200:108-10. 2000..An association between alopecia areata (AA) and coeliac disease has recently been reported...
- Coeliac disease: a histological follow-up studyM T Bardella
Department of Gastroenterology and Endocrine Diseases, Fondazione IRCCS, Ospedale Maggiore Policlinico, Mangialli and Regina Elena, Milano, Italy
Histopathology 50:465-71. 2007..To assess the histological response to a gluten-free diet (GFD) in a series of coeliac patients in clinical remission, of different ages and with varying degrees of mucosal damage at diagnosis...
- Severe heart disease in coeliac sprue and inflammatory Bowel disease: a common pathogenesis?M T Bardella
Cattedra di Gastroenterologia dell Università degli Studi, Unità Operativa di Gastroenterologia, Milan, Italy
Scand J Gastroenterol 39:1304-5. 2004
- Beneficial effects of treatment with transglutaminase inhibitor cystamine on the severity of inflammation in a rat model of inflammatory bowel diseaseLuca Elli
Centro per la Prevenzione e Diagnosi della Malattia Celiaca, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Milano, Milano, Italy
Lab Invest 91:452-61. 2011..This is the first demonstration that treatment with a CysN has an anti-inflammatory effect, reducing severity of colitis in a rat model. CysN could be tested as a possible treatment or co-treatment in IBD therapeutic trials...
- Damaging effects of gliadin on three-dimensional cell culture modelErsilia Dolfini
Department of Gastroenterology, Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena IRCCS, Via F Sforza 35, Milan 20122, Italy
World J Gastroenterol 11:5973-7. 2005..To evaluate the effects of gliadin on the oxidative environment in the "in vivo-like" model of a three-dimensional cell culture system...
- Immunoreactivity of antibodies against transglutaminase-deamidated gliadins in adult celiac diseaseMaria Letizia Falini
Department of Agrifood Molecular Science, University of Milan, Milan, Italy
Dig Dis Sci 53:2697-701. 2008..It is hypothesized that gliadin deamidation, catalysed by transglutaminase, plays a role in favoring the antigen presentation...
- microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblastsValentina Vaira
Division of Pathology, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
Clin Sci (Lond) 126:417-23. 2014..In conclusion, the analysis of miRNAs deserves further consideration for its potential use in the treatment and management of CD...
- Accuracy of ultrasonography in predicting celiac diseaseMirella Fraquelli
Postgraduate School of Gastroenterology, Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Maggiore, Milan, Italy
Arch Intern Med 164:169-74. 2004..Various ultrasonographic (US) signs have been reported in overt celiac disease (CD). The aim of this study was to investigate the diagnostic accuracy of 6 US parameters in predicting CD...
- Absence of mucosal inflammation in uncomplicated diverticular diseaseLuca Elli
Center for Prevention and Diagnosis of Celiac Disease, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via F Sforza 35, 29122, Milan, Italy
Dig Dis Sci 56:2098-103. 2011..Symptoms are aspecific and overlapping with those of irritable bowel syndrome. Nowadays, patients are often treated with antinflammatory drugs (5-aminosalicilic acid)...
- Cytogenetic characterization and cell cycle analysis of three human colon adenocarcinoma cell lines: comparison between two- and three-dimensional cell culture systemsLeda Roncoroni
Department of Biology and Genetic for Health Sciences, University of Milan, Via Viotti, Milan, Italy
Cancer Invest 28:7-12. 2010..These data suggest that the differences between the two- and three-dimensional cell culture systems do not involve chromosomal rearrangements...
- Imaging analysis of the gliadin direct effect on tight junctions in an in vitro three-dimensional Lovo cell line culture systemLuca Elli
Center for Prevention and Diagnosis of Celiac Disease, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy
Toxicol In Vitro 25:45-50. 2011..8±42.8 vs. 23.4±25.9 μm, p<0.01). Our data demonstrated that tight junction proteins are directly damaged by gliadin as shown by means of quantitative imaging analysis...
- Tissue transglutaminase antibodies in patients with end-stage heart failureMaddalena Peracchi
IRCCS Ospedale Maggiore, University of Milan, Italy
Am J Gastroenterol 97:2850-4. 2002..Moreover, tTG is a ubiquitous, multifunctional enzyme, overexpressed in experimental models of heart failure. Therefore, we assessed the specificity of tTGA assays in a large series of EmA-negative patients with end-stage heart failure...
- Resveratrol inhibits cell growth in a human cholangiocarcinoma cell lineLeda Roncoroni
Center for Prevention and Diagnosis of Celiac Disease, IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milano, Italy
Liver Int 28:1426-36. 2008..Resveratrol (RES) is a natural molecule with a reported anticancer effect, evaluated on different tumour cell lines. We tested the efficacy of RES on a cholangiocarcinoma cell line for the first time...
- Celiac-related properties of chemically and enzymatically modified gluten proteinsCristiana Berti
Dipartimento di Scienze Molecolari Agroalimentari, Universita di Milano, and Centre for the Prevention and Diagnosis of Celiac Disease, Fondazione IRCCS, Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan 20133, Italy
J Agric Food Chem 55:2482-8. 2007..These results showed that chemical deamidation of gluten may be envisaged as a way to lower the potential risk for celiac people due to widespread use of gluten as a food additive...
- Immunological comorbity in coeliac disease: associations, risk factors and clinical implicationsLuca Elli
Center for the Prevention and Diagnosis of Coeliac Disease, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via F Sforza 35, 20122, Milan, Italy
J Clin Immunol 32:984-90. 2012..Coeliac disease is frequently associated with other immunomediated diseases. Our aim was to identify immunological comorbidities and possible risk factors for their development in coeliac patients...
- Isolation and culture of fibroblasts from endoscopic duodenal biopsies of celiac patientsLeda Roncoroni
Center for Prevention and Diagnosis of Celiac Disease, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
J Transl Med 7:40. 2009..Our objective is to isolate and culture primary fibroblasts from endoscopic duodenal biopsies of celiac and non-celiac subjects, to analyze their growth patterns and the morphometric characteristics...
- Transient elastography in patients with celiac disease: a noninvasive method to detect liver involvement associated with celiac diseaseSara Massironi
Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Gastroenterology Unit 2, Milan, Italy
Scand J Gastroenterol 47:640-8. 2012..Transient elastography (TE), a noninvasive tool for assessing liver stiffness (LS), has widely been reported as an accurate surrogate marker of liver fibrosis...
- Plasma chromogranin a in patients with inflammatory bowel diseaseValentina Sciola
Gastroenterology Unit II, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, University of Milan, Milan, Italy
Inflamm Bowel Dis 15:867-71. 2009..Therefore, we aimed to evaluate CgA levels and their possible relationship with clinical and biochemical disease activity indexes in 119 IBD patients...
- Circulating ghrelin levels in celiac patientsMaddalena Peracchi
Gastroenterology, IRCCS Ospedale Maggiore, University of Milan, Milan, Italy
Am J Gastroenterol 98:2474-8. 2003..Therefore, the aim of this study was to evaluate circulating ghrelin levels in adults with untreated and treated celiac disease (CD) and, for comparison, in healthy subjects...
- Celiac disease: in vivo diagnosis by confocal endomicroscopyCristina Trovato
Division of Endoscopy, European Institute of Oncology, and Department of Medical Sciences, University of Milan, Milan, Italy
Gastrointest Endosc 65:1096-9. 2007
- High frequency of anti-endomysial reactivity in candidates to heart transplantD Prati
Blood Transfusion and Transplant Immunology Centre, University of Milan, Milano, Italy
Dig Liver Dis 34:39-43. 2002..A possible link between coeliac disease and dilated cardiomyopathy has recently been suggested...
- Risk of intestinal lymphoma in undiagnosed coeliac disease: results from a registered population with different coeliac disease prevalenceLuca Elli
Centre for the Prevention and Diagnosis of Coeliac Disease, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
Dig Liver Dis 44:743-7. 2012..Our aim is to estimate the risk of intestinal lymphoma in undiagnosed coeliac patients, evaluating the real incidences and applying different theoretical settings of coeliac prevalence...
- Cytoskeleton reorganization and ultrastructural damage induced by gliadin in a three-dimensional in vitro modelErsilia Dolfini
Department of Biology and Genetics for Health Sciences, via Viotti 3 5, 20131 Milano, Italy
World J Gastroenterol 11:7597-601. 2005..To evaluate the interplay between gliadin and LoVo cells and the direct effect of gliadin on cytoskeletal patterns...
- Chronic unexplained hypertransaminasemia may be caused by occult celiac diseaseM T Bardella
Department of Internal Medicine, Institute of Medical Sciences, University of Milan, IRCCS Ospedale Maggiore, Milan, Italy
Hepatology 29:654-7. 1999..6 (95% confidence interval 11.1-31.2). On the basis of the present findings, screening for celiac disease is an important tool in the initial diagnostic work-up of patients with chronic unexplained hypertransaminasemia...
- Effectiveness of IFN-gamma for liver abscesses in chronic granulomatous diseaseD Conte
Cattedra di Gastroenterologia, IRCCS Ospedale Maggiore, Milano, Italy
J Interferon Cytokine Res 19:705-10. 1999..No septic recurrence was observed during a 4-year follow-up period. In chronic granulomatous disease, IFN-gamma is effective not only in preventing but also in healing life-threatening acute infections...
- Evaluation of GH-IGF-I axis in adult patients with coeliac diseaseE Ferrante
Endocrinology and Diabetology Unit, Department of Medical Sciences, University of Milan, Fondazione Ospedale Maggiore Policlinico IRCCS, Pad Granelli, Via F Sforza, 35, 20122 Milan, Italy
Horm Metab Res 42:45-9. 2010..Given the absence of APAs, the cause of this pituitary dysfunction remains unclear even if a previous autoimmune involvement in some cases cannot be excluded...
- Iron-related indexes in chronic alcoholics. Effect of alcohol withdrawalD Conte
Chair of Gastroenterology, IRCCS Maggiore Hospital, Milan, Italy
Ital J Gastroenterol Hepatol 30:534-8. 1998..Increased serum transferrin saturation and ferritin levels have been reported in chronic alcoholics...
- Anti-inflammatory effects of alpha-melanocyte-stimulating hormone in celiac intestinal mucosaGualtiero Colombo
Department of Internal Medicine, Ospedale Maggiore di Milano IRCCS, Milan, Italy
Neuroimmunomodulation 10:208-16. 2002..The aim of the present research was to determine whether alpha-MSH and its receptors participate in a localized anti-inflammatory response in the duodenal mucosa of celiac patients...
- A follow-up study of patients with Zollinger-Ellison syndrome in the period 1966-2002: effects of surgical and medical treatments on long-term survivalMaurizio Quatrini
Gastroenterology Unit, University of Milan, IRCCS Ospedale Maggiore, Milan, Italy
J Clin Gastroenterol 39:376-80. 2005....
- Hemochromatosis gene mutations and iron metabolism in celiac diseaseDonatella Barisani
Department of Experimental and Environmental Medicine and Medical Biotechnology, University of Milano Bicocca, Via Cadore 48, 20052, Monza, Milan, Italy
Haematologica 89:1299-305. 2004..The aim of this study was to evaluate the prevalence of HFE mutations and their effect on iron metabolism in Italian celiac patients at diagnosis and after a gluten-free diet...
- Bone and celiac diseaseM L Bianchi
Bone Metabolic Unit, Istituto Auxologico Italiano IRCCS Via Ludovico Ariosto, 13, 20145, Milan, Italy
Calcif Tissue Int 71:465-71. 2002..For these reasons, we feel that a review of the clinical findings on bone problems in celiac disease may be useful for both gastroenterologists and osteoporosis specialists...
- Pancreatic involvement in von Hippel-Lindau disease: report of two cases and review of the literatureLuca Elli
Department of Medical Sciences, University of Milan, Milan, Italy
Am J Gastroenterol 101:2655-8. 2006..Although VHL disease is mainly diagnosed after the detection of central nervous system tumors, they may not always be the first presentation...
- Gliadin cytotoxicity and in vitro cell culturesLuca Elli
Department of Biology and Genetics, University of Milan, Via Votti 9, Milan 20100, Italy
Toxicol Lett 146:1-8. 2003..Furthermore, in addition to improving our understanding of pathogenetic mechanisms, cell cultures can also be used to test modified peptides that could replace the toxic components present in the foods that celiac patients must avoid...
- Iatrogenic ileal obstruction in a patient with Crohn's diseaseLuca P Piodi
Unità Operativa di Gastroenterologia, IRCCS Ospedale Maggiore di Milano, Via F Sforza 35, 20122 Milano, Italy
Dig Dis Sci 49:1287-90. 2004
- Prevalence of celiac disease in inflammatory bowel diseases: An IG-IBD multicentre studyGiovanni Casella
Medical Department, Desio Hospital, Milan, Italy
Dig Liver Dis 42:175-8. 2010..The aim of the present study is to assess the prevalence of celiac disease in a large series of Italian patients with inflammatory bowel disease...
- Bone in celiac diseaseM L Bianchi
Bone Metabolism Unit, Istituto Auxologico Italiano IRCCS, Milan, Italy
Osteoporos Int 19:1705-16. 2008..Finally, the current treatment options for children and adults are discussed. Recommendations for future clinical research are proposed...
- In vitro cytotoxic effect of bread wheat gliadin on the LoVo human adenocarcinoma cell lineE Dolfini
Department of Biology and Genetics, University of Milan, via Viotti 5 6, 20100 Milan, Italy
Toxicol In Vitro 16:331-7. 2002..The controls did not show any noxious effect. Our results confirm the usefulness of LoVo cells in evaluating gliadin cytotoxicity and that they can be used to investigate the biological properties of gliadin...
- Transglutaminases in inflammation and fibrosis of the gastrointestinal tract and the liverL Elli
Center for Prevention and Diagnosis of Celiac Disease, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via F Sforza, Milan, Italy
Dig Liver Dis 41:541-50. 2009..This review highlights our present understanding of transglutaminase function in gastrointestinal and liver diseases and therapeutic strategies that target transglutaminase activities...
- Bread wheat gliadin cytotoxicity: a new three-dimensional cell modelE Dolfini
Department of Biology and Genetics, University of Milan, Italy
Scand J Clin Lab Invest 63:135-41. 2003..The aim of this study was to develop a three-dimensional in vitro model to investigate the effects of gliadin on epithelial cells and broaden our understanding of the early tissue damage occurring in celiac disease...
- An unusual endoscopic feature in the duodenum of a young girl with intraluminal duodenal diverticulumS Massironi
Cattedra di Gastroenterologia, Dipartimento di Scienze Mediche, IRCCS Ospedale Maggiore, Milan, Italy
Endoscopy 34:350. 2002
- Re: Oxentenko et al.--Endoscopic markers in celiac diseaseMaria Teresa Bardella
Am J Gastroenterol 97:2923-4; author reply 2924. 2002
- Antiendomysial antibodies in patients with end-stage heart failureDaniele Prati
Am J Gastroenterol 97:218-9. 2002
- Direct gliadin cytotoxicity as a cofactor in the pathogenesis of celiac diseaseLuca Elli
Int Arch Allergy Immunol 134:88. 2004
- Adaptive changes of duodenal iron transport proteins in celiac diseaseDonatella Barisani
Department of Experimental and Environmental Medicine and Medical Biotechnology, University of Milano Bicocca, 20052 Monza, Italy
Physiol Genomics 17:316-25. 2004....
- Serologic and genetic markers of celiac disease: a sequential study in the screening of first degree relativesMargherita Bonamico
Department of Pediatrics, University of Rome La Sapienza, Viale Regina Elena 324, 00161 Rome, Italy
J Pediatr Gastroenterol Nutr 42:150-4. 2006..The prevalence of celiac disease (CD) among the relatives and the complications of an undiagnosed CD prompted us to identify a useful disease screening strategy...
- Usefulness of the organ culture system in the in vitro diagnosis of coeliac disease: a multicentre studyAntonio Picarelli
Department of Clinical Sciences, University La Sapienza, Rome, Italy
Scand J Gastroenterol 41:186-90. 2006..The objective of this study was to compare the histology and antiendomysial antibodies in culture supernatants of intestinal biopsies to validate the in vitro organ culture system as a future diagnostic tool for coeliac disease...
- IL-10 polymorphisms are associated with early-onset celiac disease and severe mucosal damage in patients of Caucasian originDonatella Barisani
Department of Experimental, Environmental Medicine and Medical Biotechnology, University of Milano Bicocca, Monza, Milan
Genet Med 8:169-74. 2006..We thus evaluated cytokine polymorphism prevalence in CD patients and population controls, and assessed the correlation between specific polymorphisms and celiacs' clinical characteristics...
- Imbalance of osteoclastogenesis-regulating factors in patients with celiac diseaseAnna Taranta
Istituto Dermopatico dell Immacolata, Istituto di Ricovero e Cura a Carattere Scientifico, Roma, Italy
J Bone Miner Res 19:1112-21. 2004..We show imbalance of cytokines relevant to bone metabolism in celiac patients' sera and the direct effect of these sera on in vitro bone cell activity...
- Should routine screening for coeliac disease be considered before starting interferon/ribavirin treatment in patients affected by chronic hepatitis C?Giovanni Casella
Eur J Gastroenterol Hepatol 16:429. 2004