G Barbara

Summary

Affiliation: University of Bologna
Country: Italy

Publications

  1. ncbi request reprint Role of antibiotic therapy on long-term germ excretion in faeces and digestive symptoms after Salmonella infection
    G Barbara
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Aliment Pharmacol Ther 14:1127-31. 2000
  2. ncbi request reprint Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome
    Giovanni Barbara
    Department of Internal Medicine and Gastroenterology, and CRBA, University of Bologna, St Orsola Hospital, Via Massarenti 9, I 40138 Bologna, Italy
    Gastroenterology 132:26-37. 2007
  3. ncbi request reprint New pathophysiological mechanisms in irritable bowel syndrome
    G Barbara
    Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
    Aliment Pharmacol Ther 20:1-9. 2004
  4. ncbi request reprint Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome
    Giovanni Barbara
    Departmentof Internal Medicine and Gastroenterology, and CRBA, University of Bologna, Italy
    Gastroenterology 126:693-702. 2004
  5. ncbi request reprint Functional gastrointestinal disorders and mast cells: implications for therapy
    G Barbara
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Neurogastroenterol Motil 18:6-17. 2006
  6. pmc A role for inflammation in irritable bowel syndrome?
    G Barbara
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Gut 51:i41-4. 2002
  7. doi request reprint Natural history of intestinal failure induced by chronic idiopathic intestinal pseudo-obstruction
    V Stanghellini
    Department of Clinical Medicine, University of Bologna, Bologna, Italy
    Transplant Proc 42:15-8. 2010
  8. doi request reprint Patient-reported outcomes and gut dysmotility in functional gastrointestinal disorders
    R F Cogliandro
    Department of Clinical Medicine, S Orsola Malpighi University Hospital, Bologna, Italy
    Neurogastroenterol Motil 23:1084-91. 2011
  9. ncbi request reprint Diagnosis and therapy of irritable bowel syndrome
    R De Giorgio
    Departments of Internal Medicine and Gastroenterology and Pharmacology, University of Bologna, Italy
    Aliment Pharmacol Ther 20:10-22. 2004
  10. ncbi request reprint Review article: Helicobacter pylori, mucosal inflammation and symptom perception--new insights into an old hypothesis
    V Stanghellini
    Department of Internal Medicine and Gastroenterology, St Orsola Hospital, University of Bologna, Via Massarenti 9, I 40138 Bologna, Italy
    Aliment Pharmacol Ther 15:28-32. 2001

Detail Information

Publications64

  1. ncbi request reprint Role of antibiotic therapy on long-term germ excretion in faeces and digestive symptoms after Salmonella infection
    G Barbara
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Aliment Pharmacol Ther 14:1127-31. 2000
    ..Acute Salmonella gastroenteritis induces long-lasting digestive symptoms in up to one-third of subjects. The role of antimicrobial therapy on persistent post-infectious symptoms is unknown...
  2. ncbi request reprint Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome
    Giovanni Barbara
    Department of Internal Medicine and Gastroenterology, and CRBA, University of Bologna, St Orsola Hospital, Via Massarenti 9, I 40138 Bologna, Italy
    Gastroenterology 132:26-37. 2007
    ..However, the underlying mechanisms remain unknown. We assessed the effect of mast cell mediators released from the colonic mucosa of IBS patients on the activation of rat sensory neurons in vitro...
  3. ncbi request reprint New pathophysiological mechanisms in irritable bowel syndrome
    G Barbara
    Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
    Aliment Pharmacol Ther 20:1-9. 2004
    ..These novel mechanisms may aid a better understanding of the complex pathophysiology of IBS and to develop new therapies...
  4. ncbi request reprint Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome
    Giovanni Barbara
    Departmentof Internal Medicine and Gastroenterology, and CRBA, University of Bologna, Italy
    Gastroenterology 126:693-702. 2004
    ..We assessed colonic mast cell infiltration, mediator release, and spatial interactions with mucosal innervation and their correlation with abdominal pain in IBS patients...
  5. ncbi request reprint Functional gastrointestinal disorders and mast cells: implications for therapy
    G Barbara
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Neurogastroenterol Motil 18:6-17. 2006
    ..g., second generation antihistamines, proteinase-activated receptor antagonists) may be useful pharmacological tools for these common disorders...
  6. pmc A role for inflammation in irritable bowel syndrome?
    G Barbara
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Gut 51:i41-4. 2002
    ..A brief review of the human and animal studies that have focused on the putative role of intestinal inflammation and infections in the pathogenesis of IBS is given...
  7. doi request reprint Natural history of intestinal failure induced by chronic idiopathic intestinal pseudo-obstruction
    V Stanghellini
    Department of Clinical Medicine, University of Bologna, Bologna, Italy
    Transplant Proc 42:15-8. 2010
    ..A substantial percentage of patients requires parenteral nutrition. Failure of this nutritional support represents an indication for small bowel transplantation...
  8. doi request reprint Patient-reported outcomes and gut dysmotility in functional gastrointestinal disorders
    R F Cogliandro
    Department of Clinical Medicine, S Orsola Malpighi University Hospital, Bologna, Italy
    Neurogastroenterol Motil 23:1084-91. 2011
    ..The present study compared clinical features, small bowel motility, and quality of life (QoL) in patients with CIIP or severe functional gastrointestinal disorders (SFGID), compared to irritable bowel syndrome (IBS)...
  9. ncbi request reprint Diagnosis and therapy of irritable bowel syndrome
    R De Giorgio
    Departments of Internal Medicine and Gastroenterology and Pharmacology, University of Bologna, Italy
    Aliment Pharmacol Ther 20:10-22. 2004
    ..A wide array of potentially useful drugs are currently under consideration in pre-clinical trials. A better understanding of the pathogenetic mechanisms underlying IBS may help to develop more effective drugs for this disease...
  10. ncbi request reprint Review article: Helicobacter pylori, mucosal inflammation and symptom perception--new insights into an old hypothesis
    V Stanghellini
    Department of Internal Medicine and Gastroenterology, St Orsola Hospital, University of Bologna, Via Massarenti 9, I 40138 Bologna, Italy
    Aliment Pharmacol Ther 15:28-32. 2001
    ..The identification of these mechanisms may provide a better understanding of the pathophysiology of H. pylori-related dyspepsia and prompt innovative therapeutic approaches...
  11. ncbi request reprint Anti-ganglioside antibodies in coeliac disease with neurological disorders
    U Volta
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Building 11, St Orsola Malpighi Hospital, Via Massarenti, 9, 40138 Bologna, Italy
    Dig Liver Dis 38:183-7. 2006
    ..Anti-ganglioside antibodies have been described in sera of coeliac patients with peripheral neuropathy and cerebellar ataxia...
  12. ncbi request reprint New insights into human enteric neuropathies
    R De Giorgio
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Neurogastroenterol Motil 16:143-7. 2004
    ..The study of the ENS abnormalities in gut dysmotility provides a framework to better understand the mechanisms involved in degeneration and neuronal loss and fosters the development of targeted therapeutic options...
  13. ncbi request reprint Effect of mesalazine on mucosal immune biomarkers in irritable bowel syndrome: a randomized controlled proof-of-concept study
    R Corinaldesi
    Department of Clinical Medicine and Center for Applied Biomedical Research, University of Bologna, Bologna, Italy
    Aliment Pharmacol Ther 30:245-52. 2009
    ..Intestinal immune infiltration contributes to symptoms in patients with irritable bowel syndrome (IBS)...
  14. ncbi request reprint Chronic intestinal pseudo-obstruction: manifestations, natural history and management
    V Stanghellini
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Neurogastroenterol Motil 19:440-52. 2007
    ..This article focuses on the main clinical features, the management and long-term outcome of patients affected by CIPO, with particular emphasis on those aspects which remain a matter of debate...
  15. ncbi request reprint Gastro-oesophageal reflux and interstitial lung disease
    B Salvioli
    Department of Internal Medicine and Gastroenterology, S Orsola Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Dig Liver Dis 38:879-84. 2006
    ..Gastro-oesophageal reflux appears to be more prevalent in idiopathic pulmonary fibrosis than in controls and in patients with secondary pulmonary fibrosis, but its contribution to interstitial lung disease remains unsettled...
  16. ncbi request reprint Use of macrogol 4000 in chronic constipation
    R De Giorgio
    Department of Clinical Medicine, School of Medicine, Alma Mater Studiorum University, Bologna, Italy
    Eur Rev Med Pharmacol Sci 15:960-6. 2011
    ..Lifestyle changes do not usually meet with complete patient satisfaction. Other treatments include different types of laxatives. Of these, osmotic laxatives appear one of the most effective and are, therefore, frequently prescribed...
  17. ncbi request reprint Review article: the pharmacological treatment of acute colonic pseudo-obstruction
    R De Giorgio
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Aliment Pharmacol Ther 15:1717-27. 2001
    ..Among these agents, the potential of 5-hydroxytryptamine-4 receptor agonists and motilin receptor agonists is discussed...
  18. ncbi request reprint Unsolved problems in the management of patients with gastro-oesophageal reflux disease
    V Stanghellini
    Department of Internal Medicine and Gastroenterology, University of Bologna, Policlinico S Orsola Malpighi, Via Massarenti, 9 Bologna 1 40138, Italy
    Dig Liver Dis 35:843-8. 2003
    ..The high prevalence of gastro-oesophageal reflux disease in the general population and the relatively high management costs should prompt any doctor to seek the best possible therapeutic approach...
  19. ncbi request reprint Idiopathic achalasia is not allelic to alacrima achalasia adrenal insufficiency syndrome at the ALADIN locus
    G Di Nardo
    Department of Internal Medicine and Gastroenterology, University of Bologna, St Orsola Malpighi Hospital, Via Massarenti, 9, I 40138 Bologna, Italy
    Dig Liver Dis 37:312-5. 2005
    ..e. alacrima, achalasia and adrenocorticotropin-resistant adrenal insufficiency with neurological impairment) have mutations of the alacrima achalasia adrenal insufficiency syndrome (AAAS) gene...
  20. ncbi request reprint Predictors of gastroparesis in out-patients with secondary and idiopathic upper gastrointestinal symptoms
    V Stanghellini
    Department of Internal Medicine, University of Bologna, St Orsola Malpighi Hospital, Via Massarenti 9, 40138 Bologna, Italy
    Dig Liver Dis 35:389-96. 2003
    ..Delayed gastric emptying occurs frequently in patients with upper gastrointestinal symptoms associated with functional or organic diseases...
  21. ncbi request reprint Abnormalities of somatic peptide-containing nerves supplying the pelvic floor of women with genitourinary prolapse and stress urinary incontinence
    P Busacchi
    Department of Obstetrics and Gynecology, St Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Urology 63:591-5. 2004
    ....
  22. ncbi request reprint Thrombotic thrombocytopenic purpura mimicking an acute meningoencephalitis
    F Tovoli
    Dipartimento di Medicina Clinica, Universita di Bologna, Bologna, Italy
    Acta Clin Belg 66:55-6. 2011
    ..Thrombotic thrombocytopenic purpura should be considered in the differential diagnosis of patients presenting with any neurological abnormalities, anaemia and unexplained thrombocytopenia...
  23. pmc Intestinal inflammation and activation of sensory nerve pathways: a functional and morphological study in the nematode infected rat
    R De Giorgio
    Department of Internal Medicine, University of Bologna, Italy
    Gut 49:822-7. 2001
    ..As the pseudoaffective response is capsaicin sensitive, the rightward shift of the response is likely the consequence of the decrease in NK-1 receptors in the sensory pathways...
  24. ncbi request reprint Upper gastrointestinal bleeding due to duodenal metastasis from primary lung carcinoma
    C Cremon
    Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
    Dig Liver Dis 34:141-3. 2002
    ..Herein, we report a case of duodenal metastatic involvement leading to severe upper gastrointestinal bleeding in the absence of symptoms referable to the primary tumour...
  25. ncbi request reprint [Gastroesophageal reflux disease: therapeutic features (Part II)]
    R Corinaldesi
    Dipartimento di Medicina Interna e Gastroenterologia, Universita degli Studi di Bologna, Italia
    Clin Ter 158:165-72. 2007
    ..Surgery, based on anti-reflux procedures, and endoscopic approaches may have a role in the management of patients with GERD...
  26. ncbi request reprint [Gastroesophageal reflux disease: clinical and pathophysiological features (part I)]
    R Corinaldesi
    Dipartimento di Medicina Interna e Gastroenterologia, Universita degli Studi di Bologna, Italia
    Clin Ter 158:77-83. 2007
    ..Moreover, barium swallow X-ray, 24-h esophageal pH monitoring and gastro-esophageal manometry can be useful to support diagnosis in some unusual cases or in cases partially or unresponsive to standard pharmacologic treatment...
  27. doi request reprint Colonic mucosal mediators from patients with irritable bowel syndrome excite enteric cholinergic motor neurons
    B Balestra
    Department of Forensic Medicine, Pharmacology and Toxicology, University of Pavia, Pavia, Italy
    Neurogastroenterol Motil 24:1118-e570. 2012
    ..Mediators released in the mucosal milieu have been suggested to be involved in visceral hypersensitivity and abdominal pain in patients with irritable bowel syndrome (IBS). However, their impact on myenteric neurons remains unsettled...
  28. doi request reprint Chronic intestinal pseudo-obstruction related to viral infections
    R De Giorgio
    Department of Clinical Medicine, University of Bologna, Bologna, Italy
    Transplant Proc 42:9-14. 2010
    ..The review thus provides some new perspectives in the pathophysiology and perhaps targeted treatment of CIIPO...
  29. ncbi request reprint Dyspepsia and dyspepsia subgroups. Not all roads lead to Rome
    V Stanghellini
    Department of Internal Medicine and Gastroenterology, University of Bologna S Orsola Malpighi Hospital, Italy
    Dig Liver Dis 34:316-8. 2002
  30. ncbi request reprint The beta3-adrenoceptor agonist SR58611A ameliorates experimental colitis in rats
    V Vasina
    Department of Pharmacology, University of Bologna, Bologna, Italy
    Neurogastroenterol Motil 20:1030-41. 2008
    ..Amelioration of experimental colitis by the selective beta(3)-adrenoceptor agonist SR58611A suggests that beta(3)-adrenoceptors may represent a therapeutic target in gut inflammation...
  31. doi request reprint Submucous rather than myenteric neurons are activated by mucosal biopsy supernatants from irritable bowel syndrome patients
    S Buhner
    Human Biology, Technische Universitat Munchen, Germany
    Neurogastroenterol Motil 24:1134-e572. 2012
    ..Based on the concept that mucosa-nerve signaling is altered in IBS, we tested in this study whether the nerve sensitizing effect of IBS mucosal biopsy supernatants is more prominent in the submucous than myenteric plexus...
  32. ncbi request reprint Clinical findings and anti-neuronal antibodies in coeliac disease with neurological disorders
    U Volta
    Dept of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, Italy
    Scand J Gastroenterol 37:1276-81. 2002
    ..In a large series of adult coeliac disease patients, we investigated the prevalence of neurological disorders and anti-neuronal antibodies, along with the clinical course...
  33. doi request reprint Slow gallbladder emptying reverts to normal but small intestinal transit of a physiological meal remains slow in celiac patients during gluten-free diet
    F Benini
    Gastroenterology Unit and Histopathology Unit, University and Spedali Civili of Brescia, Brescia, Italy
    Neurogastroenterol Motil 24:100-7, e79-80. 2012
    ..Our aims were to quantitate non-invasively small intestinal transit time and GB emptying during administration of a physiological and palatable solid meal, and to assess the effect of gluten-free diet (GFD)...
  34. ncbi request reprint Pancreatic involvement in systemic sarcoidosis. A case report
    E Romboli
    Department of Internal Medicine and Gastroenterology, Sant Orsola Hospital, Alma Mater Studiorum University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Dig Liver Dis 36:222-7. 2004
    ..Endoscopic ultrasonography represents the technique of choice used to confirm the clinical suspicion of pancreatic inflammation...
  35. ncbi request reprint Almost all irritable bowel syndromes are post-infectious and respond to probiotics: controversial issues
    Giovanni Barbara
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Dig Dis 25:245-8. 2007
    ..Probiotics have been claimed to be of some benefit in IBS, but the majority of studies have been performed in non-specific IBS rather than in PI-IBS and a number of issues still remain to be elucidated...
  36. ncbi request reprint Evidence for mast cell involvement in human postoperative ileus: a novel link
    Roberto De Giorgio
    Department of Internal Medicine and Gastroenterology, Centro Unificato di Ricerca BioMedica Applicata, University of Bologna, Italy
    Gut 57:5-7. 2008
  37. doi request reprint A case of paraneoplastic inflammatory neuropathy of the gastrointestinal tract related to an underlying neuroblastoma: successful management with immunosuppressive therapy
    Alessandra Martin
    Department of Pediatric Surgery, Meyer Children s Hospital, University of Florence, Italy
    J Pediatr Gastroenterol Nutr 46:457-60. 2008
  38. ncbi request reprint Anti-HuD-induced neuronal apoptosis underlying paraneoplastic gut dysmotility
    Roberto De Giorgio
    Department of Internal Medicine, University of Bologna, Italy
    Gastroenterology 125:70-9. 2003
    ....
  39. pmc Chronic intestinal pseudo-obstruction
    Alexandra Antonucci
    Department of Internal Medicine and Gastroenterology, St Orsola Malpighi Hospital, Via Massarenti 9, Bologna I 40138, Italy
    World J Gastroenterol 14:2953-61. 2008
    ..Treatment of intestinal pseudo-obstruction involves nutritional, pharmacological and surgical therapies, but it is often unsatisfactory and the long-term outcome is generally poor in the majority of cases...
  40. pmc Neurogenic chronic intestinal pseudo-obstruction: antineuronal antibody-mediated activation of autophagy via Fas
    Roberto De Giorgio
    Department of Internal Medicine and Gastroenterology, Centro Unificato di Ricerca BioMedica Applicata, University of Bologna, Bologna, Italy
    Gastroenterology 135:601-9. 2008
    ..In this study we tested the hypothesis that sera from a subpopulation of patients with CIP contain autoantibodies that activate autophagy via a Fas-dependent pathway in cultured human neuroblastoma SH-Sy5Y cells...
  41. ncbi request reprint Is irritable bowel syndrome an inflammatory disorder?
    Roberto De Giorgio
    Department of Internal Medicine and Gastroenterology, Building 5 Nuove Patologie, St Orsola Malpighi Hospital, Via Massarenti, 9, I 40138 Bologna, Italy
    Curr Gastroenterol Rep 10:385-90. 2008
    ..The identification of mucosal inflammation in IBS has pathophysiologic implications and paves the way for novel therapeutic options...
  42. doi request reprint Serine proteases: new players in diarrhoea-predominant irritable bowel syndrome
    Giovanni Barbara
    Department of Internal Medicine and Gastroenterology, St Orsola Hospital, Building No 5, Via Massarenti 9, I 40138 Bologna, Italy
    Gut 57:1035-7. 2008
  43. pmc Altered prejunctional modulation of intestinal cholinergic and noradrenergic pathways by alpha2-adrenoceptors in the presence of experimental colitis
    Corrado Blandizzi
    Division of Pharmacology and Chemotherapy, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Via Roma, 55, Pisa 56126, Italy
    Br J Pharmacol 139:309-20. 2003
    ..Evidence was obtained that such modulatory actions depend on an increased expression of alpha(2A)-adrenoceptors within the enteric nervous system...
  44. ncbi request reprint New developments in the treatment of functional dyspepsia
    Vincenzo Stanghellini
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Drugs 63:869-92. 2003
    ..e., P2X2/3 receptors), NMDA receptors (NR2B subtype), protease-activated receptor-2, the vanilloid receptor-1, tachykinin receptors (NK(1)/NK(2)) and cholecystokinin (CCK)(1) receptors...
  45. ncbi request reprint Clinical and morphofunctional features of idiopathic myenteric ganglionitis underlying severe intestinal motor dysfunction: a study of three cases
    Roberto De Giorgio
    Department of Internal Medicine, University of Bologna, Italy
    Am J Gastroenterol 97:2454-9. 2002
    ..The immunosuppressive approach deserves further investigation in patients with severe gut motor abnormalities attributable to idiopathic myenteric ganglionitis...
  46. ncbi request reprint Natural history of chronic idiopathic intestinal pseudo-obstruction in adults: a single center study
    Vincenzo Stanghellini
    Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
    Clin Gastroenterol Hepatol 3:449-58. 2005
    ..Intestinal motor abnormalities have long been identified in CIIP patients. Little is known of the natural history of the disease in adults. This study evaluated the clinical course of CIIP over time...
  47. ncbi request reprint Inflammation as a cause of functional bowel disorders
    Hans Tornblom
    Karolinska Institutet, Department of Medicine, Karolinska University Hospital, Stockholm, Sweden
    Scand J Gastroenterol 40:1140-8. 2005
  48. pmc Role for protease activity in visceral pain in irritable bowel syndrome
    Nicolas Cenac
    Department of Pharmacology and Therapeutics, University of Calgary, Calgary, Alberta, Canada
    J Clin Invest 117:636-47. 2007
    ..Our study establishes that proteases are released in IBS and that they can directly stimulate sensory neurons and generate hypersensitivity symptoms through the activation of PAR2...
  49. ncbi request reprint Inflammatory neuropathies of the enteric nervous system
    Roberto De Giorgio
    Department of Internal Medicine and Gastroenterology, University of Bologna, St Orsola Malpighi Hospital, Via Massarenti 9, I 40138 Bologna, Italy
    Gastroenterology 126:1872-83. 2004
    ....
  50. ncbi request reprint Mucosal barrier defects in irritable bowel syndrome. Who left the door open?
    Giovanni Barbara
    Am J Gastroenterol 101:1295-8. 2006
    ..Further work has now to be done to better understand the interplay among luminal factors, epithelial cells, and mucosal immunocytes in the pathogenesis of IBS...
  51. ncbi request reprint Enteric neuropathology of congenital intestinal obstruction: A case report
    Giovanni Di Nardo
    Department of Pediatrics, Pediatric Gastroenterology Unit, University of Rome La Sapienza, Rome, Italy
    World J Gastroenterol 12:5229-33. 2006
    ..Such ENS changes mimic neuronal abnormalities observed in intestinal pseudo-obstruction...
  52. ncbi request reprint Prokinetics in the treatment of acute intestinal pseudo-obstruction
    Roberto De Giorgio
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna I 40138, Italy
    IDrugs 7:160-5. 2004
    ..New colokinetic agents, including 5-HT(4) receptor agonists and motilides, may represent other useful therapeutic options for Ogilvie's syndrome...
  53. ncbi request reprint Interactions between commensal bacteria and gut sensorimotor function in health and disease
    Giovanni Barbara
    Department of Internal Medicine and Gastroenterology, Univeristy of Bologna, Bologna, Italy
    Am J Gastroenterol 100:2560-8. 2005
    ..The potential benefit of antibiotic and probiotic therapy is currently under investigation and opens new perspectives in irritable bowel syndrome treatment...
  54. ncbi request reprint Immune-mediated neural dysfunction in a murine model of chronic Helicobacter pylori infection
    Premysl Bercik
    Intestinal Diseases Research Programme, McMaster University, Hamilton, Ontario, Canada
    Gastroenterology 123:1205-15. 2002
    ..Neuromuscular changes producing dysmotility and hyperalgesia may underlie symptom generation in functional gastrointestinal disorders. We investigated whether chronic Helicobacter pylori-induced gastritis causes neuromuscular dysfunction...
  55. ncbi request reprint Neurology and neuropathology of the pancreatic innervation
    Beatrice Salvioli
    JOP 3:26-33. 2002
  56. ncbi request reprint Dyspeptic symptoms and gastric emptying in the irritable bowel syndrome
    Vincenzo Stanghellini
    Department of Internal Medicine, S Orsola Malpighi University Hospital, Bologna, Italy
    Am J Gastroenterol 97:2738-43. 2002
    ..Whether overlapping dyspepsia correlates with gastric emptying abnormalities in IBS patients has not been clarified. This study aimed to evaluate gastric emptying of solids and its relationship with dyspeptic symptoms in IBS patients...
  57. ncbi request reprint Enteric neuroplasticity evoked by inflammation
    Valentina Vasina
    Department of Pharmacology, University of Bologna, St Orsola Malpighi Hospital, Italy
    Auton Neurosci 126:264-72. 2006
    ..A better comprehension of ENS plasticity during inflammation could be instrumental to develop new therapeutic options for patients with IBD and inflammatory enteric neuropathies...
  58. ncbi request reprint Chronic intestinal pseudo-obstruction
    Rosanna F Cogliandro
    Department of Internal Medicine and Gastroenterology, University of Bologna, and St Orsola Malpighi Hospital, Bologna, Italy
    Best Pract Res Clin Gastroenterol 21:657-69. 2007
    ..The main pathogenetic and clinical features of the syndrome, together with current management recommendations are reviewed in this chapter...
  59. ncbi request reprint Proteases in irritable bowel syndrome: a lot more than just digestive enzymes
    Giovanni Barbara
    Clin Gastroenterol Hepatol 5:548-9. 2007
  60. ncbi request reprint A novel locus for syndromic chronic idiopathic intestinal pseudo-obstruction maps to chromosome 8q23-q24
    Alessia Deglincerti
    Laboratory of Medical Genetics, Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Bologna, Italy
    Eur J Hum Genet 15:889-97. 2007
    ..01). Our data strongly support the presence of a new genetic locus associated with CIIP, long-segment Barrett esophagus, and cardiac involvement on chromosome 8...
  61. ncbi request reprint Sympathetic hyperactivity in patients with ulcerative colitis
    Simona Maule
    Autonomic Unit, S Vito Hospital, University of Turin, Turin, Italy
    Clin Auton Res 17:217-20. 2007
    ..At rest, LF/HF ratios were significantly (P < 0.05) higher in chronic UC patients (2.4 +/- 1.6) compared to controls (1.2 +/- 1.0). Our results suggest a higher sympathetic tone at rest in patients with chronic UC...
  62. ncbi request reprint Sera of patients with celiac disease and neurologic disorders evoke a mitochondrial-dependent apoptosis in vitro
    Elisabetta Cervio
    Department of Physiological and Pharmacological Sciences, University of Pavia, Pavia, Italy
    Gastroenterology 133:195-206. 2007
    ..The mechanisms underlying neurologic impairment in celiac disease remain unknown. We tested whether antineuronal antibody-positive sera of patients with celiac disease evoke neurodegeneration via apoptosis in vitro...
  63. ncbi request reprint Novel therapeutic targets for enteric nervous system disorders
    Roberto De Giorgio
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Trends Pharmacol Sci 28:473-81. 2007
    ....
  64. ncbi request reprint 5-HT7 receptors modulate peristalsis and accommodation in the guinea pig ileum
    Marcello Tonini
    Department of Physiological and Pharmacological Sciences, University of Pavia, Pavia, Italy
    Gastroenterology 129:1557-66. 2005
    ..In this study, we evaluated the expression of 5-HT7 receptors in the guinea pig ileum and their role in peristalsis and accommodation of the circular muscle...