Mario Barbagallo

Summary

Affiliation: University of Palermo
Country: Italy

Publications

  1. ncbi request reprint Magnesium intake in the pathophysiology and treatment of the cardiometabolic syndrome: where are we in 2006?
    Mario Barbagallo
    Department of Geriatrics, Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    J Cardiometab Syndr 1:356-7. 2006
  2. ncbi request reprint Bisoprolol and captopril effects on insulin receptor tyrosine kinase activity in essential hypertension
    L J Dominguez
    Division of Endocrinology, Metabolism and Hypertension, Wayne State University, School of Medicine and VA Medical Center, Detroit, Michigan, USA
    Am J Hypertens 10:1349-55. 1997
  3. ncbi request reprint Magnesium metabolism in type 2 diabetes mellitus, metabolic syndrome and insulin resistance
    Mario Barbagallo
    Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    Arch Biochem Biophys 458:40-7. 2007
  4. ncbi request reprint Magnesium metabolism in hypertension and type 2 diabetes mellitus
    Mario Barbagallo
    Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    Am J Ther 14:375-85. 2007
  5. ncbi request reprint Quality of life in osteoporotic women with inadequate clinical response to antiresorptive drugs: results from the ICARO study
    Mario Barbagallo
    Division of Geriatrics, Department of Internal Medicine and Emergent Pathologies, University of Palermo, Palermo, Italy
    Aging Clin Exp Res 19:24-7. 2007
  6. doi request reprint Diagnosing and managing thyroid disease in the nursing home
    Ligia J Dominguez
    Geriatric Unit, Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    J Am Med Dir Assoc 9:9-17. 2008
  7. ncbi request reprint Blood pressure and cardiovascular risk profiles of Africans who migrate to a Western country
    Ligia J Dominguez
    Geriatric Unit, Department of Clinical Medicine and Emerging Pathologies, University of Palermo, Italy
    Ethn Dis 18:512-8. 2008
  8. doi request reprint Magnesium homeostasis and aging
    Mario Barbagallo
    Geriatric Unit, Department of Internal Medicine and Emergent Pathologies, University of Palermo, Italy
    Magnes Res 22:235-46. 2009
  9. ncbi request reprint Magnesium and aging
    M Barbagallo
    Mario Barbagallo, MD Viale F Scaduto 6 c, 90144 Palermo, Italy
    Curr Pharm Des 16:832-9. 2010
  10. ncbi request reprint Age, homocysteine, and oxidative stress: relation to hypertension and type 2 diabetes mellitus
    Ligia J Dominguez
    Geriatric Unit, Department of Clinical Medicine and Emerging Pathologies, University of Palermo, Palermo, Italy
    J Am Coll Nutr 29:1-6. 2010

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Magnesium intake in the pathophysiology and treatment of the cardiometabolic syndrome: where are we in 2006?
    Mario Barbagallo
    Department of Geriatrics, Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    J Cardiometab Syndr 1:356-7. 2006
  2. ncbi request reprint Bisoprolol and captopril effects on insulin receptor tyrosine kinase activity in essential hypertension
    L J Dominguez
    Division of Endocrinology, Metabolism and Hypertension, Wayne State University, School of Medicine and VA Medical Center, Detroit, Michigan, USA
    Am J Hypertens 10:1349-55. 1997
    ..Specific insulin binding was not affected by these two agents. Thus, both captopril and bisoprolol may have favorable but different effects on TK activity and insulin action at the cellular level...
  3. ncbi request reprint Magnesium metabolism in type 2 diabetes mellitus, metabolic syndrome and insulin resistance
    Mario Barbagallo
    Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    Arch Biochem Biophys 458:40-7. 2007
    ....
  4. ncbi request reprint Magnesium metabolism in hypertension and type 2 diabetes mellitus
    Mario Barbagallo
    Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    Am J Ther 14:375-85. 2007
    ....
  5. ncbi request reprint Quality of life in osteoporotic women with inadequate clinical response to antiresorptive drugs: results from the ICARO study
    Mario Barbagallo
    Division of Geriatrics, Department of Internal Medicine and Emergent Pathologies, University of Palermo, Palermo, Italy
    Aging Clin Exp Res 19:24-7. 2007
    ..The aim of the present study was to evaluate the impact of the clinical response to treatment on the health-related quality of life in women with postmenopausal osteoporosis...
  6. doi request reprint Diagnosing and managing thyroid disease in the nursing home
    Ligia J Dominguez
    Geriatric Unit, Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    J Am Med Dir Assoc 9:9-17. 2008
    ..However, in the long-term setting, the possibility of thyroid dysfunction can be more often investigated, and the consideration of treatment and follow-up is needed to improve quality of life of affected older people...
  7. ncbi request reprint Blood pressure and cardiovascular risk profiles of Africans who migrate to a Western country
    Ligia J Dominguez
    Geriatric Unit, Department of Clinical Medicine and Emerging Pathologies, University of Palermo, Italy
    Ethn Dis 18:512-8. 2008
    ..We conducted a community survey to evaluate cardiovascular risk in Africans who recently migrated to Italy...
  8. doi request reprint Magnesium homeostasis and aging
    Mario Barbagallo
    Geriatric Unit, Department of Internal Medicine and Emergent Pathologies, University of Palermo, Italy
    Magnes Res 22:235-46. 2009
    ..Mg deficit associated to aging may be at least one of the pathophysiological links that may help to explain the interactions between inflammation and oxidative stress with the aging process and many age-related diseases...
  9. ncbi request reprint Magnesium and aging
    M Barbagallo
    Mario Barbagallo, MD Viale F Scaduto 6 c, 90144 Palermo, Italy
    Curr Pharm Des 16:832-9. 2010
    ....
  10. ncbi request reprint Age, homocysteine, and oxidative stress: relation to hypertension and type 2 diabetes mellitus
    Ligia J Dominguez
    Geriatric Unit, Department of Clinical Medicine and Emerging Pathologies, University of Palermo, Palermo, Italy
    J Am Coll Nutr 29:1-6. 2010
    ..We evaluated these parameters in relation to age and the presence of hypertension and type 2 diabetes mellitus...
  11. doi request reprint Oral magnesium supplementation improves vascular function in elderly diabetic patients
    Mario Barbagallo
    Geriatric Unit, Dept of Internal Medicine and Emergent Pathologies, University of Palermo, Italy
    Magnes Res 23:131-7. 2010
    ..9%; p < 0.05). No significant differences were found, either in ion-Mg or endothelial function, in the control group. In conclusion, the present study suggests that oral Mg improves endothelial function in diabetic elderly subjects...
  12. ncbi request reprint Collagen overglycosylation: a biochemical feature that may contribute to bone quality
    Ligia J Dominguez
    Geriatric Unit, University of Palermo, Palermo, Italy
    Biochem Biophys Res Commun 330:1-4. 2005
    ..Specific actions on collagen of drugs used for bone protection should be explored in future studies...
  13. ncbi request reprint Metabolic syndrome therapy: prevention of vascular injury by antidiabetic agents
    Ligia J Dominguez
    Geriatric Unit, Department of Internal Medicine, University of Palermo, viale F Scaduto 6 c, 90144 Palermo, Italy
    Curr Hypertens Rep 7:110-6. 2005
    ..In this article, we review the oral agents used to treat type 2 diabetes and the metabolic syndrome, and their effects on vascular tissue...
  14. ncbi request reprint [Osteoporosis and diabetes]
    L J Dominguez
    U O di Geriatria, Universita degli Studi di Palermo, Italy
    Reumatismo 56:235-41. 2004
    ..A better understanding of these mechanisms may help implement the prevention of fractures in the growing population of mature diabetics...
  15. ncbi request reprint Effects of glutathione on red blood cell intracellular magnesium: relation to glucose metabolism
    M Barbagallo
    Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    Hypertension 34:76-82. 1999
    ..These data demonstrate a direct action of glutathione both in vivo and in vitro to enhance intracellular magnesium and a clinical linkage between cellular magnesium, GSH/GSSG ratios, and tissue glucose metabolism...
  16. ncbi request reprint Effects of aging on serum ionized and cytosolic free calcium: relation to hypertension and diabetes
    M Barbagallo
    Institute of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy
    Hypertension 34:902-6. 1999
    ..The data also suggest that studies of the aging process should be limited to subjects with normal blood pressure and glucose tolerance...
  17. ncbi request reprint Protective effects of captopril against ischemic stress: role of cellular Mg
    M Barbagallo
    Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    Hypertension 34:958-63. 1999
    ....
  18. ncbi request reprint Effects of vitamin E and glutathione on glucose metabolism: role of magnesium
    M Barbagallo
    Institute of Internal Medicine and Geriatrics University of Palermo, Palermo, Italy
    Hypertension 34:1002-6. 1999
    ..78, P=0.003). These data show a clinical link between vitamin E administration, cellular magnesium, GSH/GSSG ratio, and tissue glucose metabolism. Further studies are needed to explore the cellular mechanism(s) of this association...
  19. ncbi request reprint Cardiovascular risk factors in South America and the Caribbean
    L J Dominguez
    Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    Ethn Dis 9:468-78. 1999
    ..The agenda of any lifestyle-related disease control program should include the promotion of healthy diet, exercise, and should encourage decreasing tobacco and alcohol usage...
  20. ncbi request reprint Efficacy and tolerability of lercanidipine in monotherapy in elderly patients with isolated systolic hypertension
    M Barbagallo
    Institute of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy
    Aging (Milano) 12:375-9. 2000
    ..These data indicate that lercanidipine, used as monotherapy once a day, is effective in lowering elevated systolic blood pressure in elderly patients, and is well tolerated...
  21. ncbi request reprint Altered cellular magnesium responsiveness to hyperglycemia in hypertensive subjects
    M Barbagallo
    Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    Hypertension 38:612-5. 2001
    ....
  22. ncbi request reprint Role of magnesium in insulin action, diabetes and cardio-metabolic syndrome X
    Mario Barbagallo
    Institute of Internal Medicine and Geriatrics, University of Palermo, Via F Scaduto 6 C, Palermo, Italy
    Mol Aspects Med 24:39-52. 2003
    ..We further suggest that a reduced intracellular Mg concentration might be the missing link helping to explain the epidemiological association between NIDDM and hypertension...
  23. ncbi request reprint Insulin-mimetic action of vanadate: role of intracellular magnesium
    M Barbagallo
    Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    Hypertension 38:701-4. 2001
    ....
  24. ncbi request reprint [The discovery of insulin: what really happened 80 years ago]
    L J Dominguez
    Istituto di Clinica Medica, Universita degli Studi di Palermo
    Ann Ital Med Int 16:155-62. 2001
    ..Collip who has hardly ever been associated with this event, culminated in the discovery of insulin...
  25. pmc Curcumin, inflammation, ageing and age-related diseases
    E Sikora
    Laboratory of Molecular Bases of Ageing, Nencki Institute of Experimental Biology, PAS, Warsaw, Poland
    Immun Ageing 7:1. 2010
    ..In this review we consider the possibility of the spice curcumin, a powerful antioxidant and anti-inflammatory agent possibly capable of improving the health status of the elderly...
  26. ncbi request reprint Cardiovascular risk factors in centenarians
    Antonio Galioto
    Geriatric Section, Department of Internal Medicine and Emerging Pathologies, University of Palermo, Viale Fco Scaduto 6 c, 90144 Palermo, Italy
    Exp Gerontol 43:106-13. 2008
    ..Cardiovascular risk factors mirror the factors that contribute to longevity. Hence, it is not surprising that these risk factors are less prevalent in centenarians when compared to younger old individuals...
  27. ncbi request reprint Intermittent intramuscular clodronate therapy: a valuable option for older osteoporotic women
    Ligia J Dominguez
    Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, viale F Scaduto 6 c, 90144 Palermo, Italy
    Age Ageing 34:633-6. 2005
  28. ncbi request reprint Therapeutic options in osteoporosis
    Ligia J Dominguez
    Geriatric Unit, Department of Clinical Medicine and Emergent Pathologies, University of Palermo, Italy
    Acta Biomed 81:55-65. 2010
    ..This article reviews the available nonpharmacologic and pharmacologic interventions -proved to be effective- that may be implemented to reduce the risk of osteoporotic fractures...
  29. doi request reprint Azithromycin in an older woman with diabetic gastroparesis
    Loredana Sutera
    Geriatric Unit, Post Graduate School of Geriatrics, University of Palermo, Italy
    Am J Ther 15:85-8. 2008
    ....
  30. doi request reprint Glucose control in the older patient: from intensive, to effective and safe
    Ligia J Dominguez
    University of Palermo, Palermo, Italy
    Aging Clin Exp Res 22:274-80. 2010
    ..The use of agents with a good safety profiles and with the least possibility of causing hypoglycemia is warranted...
  31. doi request reprint Physiology of the aging bone and mechanisms of action of bisphosphonates
    Ligia J Dominguez
    Geriatric Unit, Department of Internal Medicine and Specialties, University of Palermo, viale F Scaduto 6 c, 90144, Palermo, Italy
    Biogerontology 12:397-408. 2011
    ..g., risedronate) may allow better access to osteocyte network. Effects of BPs on bone senescence, cancer cells apoptosis and prevention of cardiovascular calcifications may open new avenues for biogerontological research...
  32. doi request reprint Altered ionized magnesium levels in mild-to-moderate Alzheimer's disease
    Mario Barbagallo
    Chair of Geriatrics, Department of Internal Medicine and Medical Specialties DIMIS, University of Palermo, Italy
    Magnes Res 24:S115-21. 2011
    ..24 p<0.05), while no significant correlations were found in this group of patients between magnesium and ADL or IADL. Our results show the presence of subclinical alterations in Mg-ion in patients with mild to moderate AD...
  33. pmc Magnesium and muscle performance in older persons: the InCHIANTI study
    Ligia J Dominguez
    Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy
    Am J Clin Nutr 84:419-26. 2006
    ..The role of magnesium in maintaining muscle integrity and function in older adults is largely unknown...
  34. ncbi request reprint Serum ionized magnesium levels in relation to metabolic syndrome in type 2 diabetic patients
    Francesco Corica
    Department of Internal Medicine, University of Messina, Messina, Italy
    J Am Coll Nutr 25:210-5. 2006
    ..To evaluate circulating serum ionized magnesium (i-Mg) concentrations in patients with type 2 diabetes mellitus, and to investigate its relationship with the components of the metabolic syndrome...
  35. doi request reprint Anti-aging medicine: pitfalls and hopes
    Ligia J Dominguez
    Geriatric Unit, Department of Clinical Medicine and Emerging Pathologies, University of Palermo, Palermo, Italy
    Aging Male 12:13-20. 2009
    ..This article reviews some of these advances and places the extravagant claims of anti-aging medicine in perspective. We conclude that a balanced diet of moderate proportions and exercise remain today the only proven fountain of youth...
  36. ncbi request reprint The cardiometabolic syndrome and sarcopenic obesity in older persons
    Ligia J Dominguez
    Geriatric Unit, Department of Internal Medicine, University of Palermo, Italy
    J Cardiometab Syndr 2:183-9. 2007
    ..A better understanding of the pathophysiologic mechanisms of sarcopenic obesity may help to elucidate the complex relationship between CMS and mortality/morbidity in older adults...
  37. doi request reprint Combination of intensive cognitive rehabilitation and donepezil therapy in Alzheimer's disease (AD)
    Marcello Giordano
    Alzheimer Center, Division of Geriatrics, Ospedale Ingrassia, ASP di Palermo, Palermo, Via La Loggia 5, 90100 Palermo, Italy
    Arch Gerontol Geriatr 51:245-9. 2010
    ..Our results suggest benefit of an intensive ROT program in dementia patients receiving donepezil that seems to be maintained as far as ROT is continued by the caregiver...
  38. doi request reprint Systemic immune responses in Alzheimer's disease: in vitro mononuclear cell activation and cytokine production
    Mariavaleria Pellicano
    Dipartimento di Biopatologia e Biotecnologie Mediche e Forensi, Universita di Palermo, Palermo, Italy
    J Alzheimers Dis 21:181-92. 2010
    ..These results support the involvement of systemic immunity in AD patients. However, our study is an observational one so we cannot draw a conclusion about its contribution to the pathophysiology of the disease...