Research Topics
| Mario BarbagalloSummaryAffiliation: University of Palermo Country: Italy Publications
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Detail Information
Publications
Bisoprolol and captopril effects on insulin receptor tyrosine kinase activity in essential hypertensionL J Dominguez
Division of Endocrinology, Metabolism and Hypertension, Wayne State University, School of Medicine and VA Medical Center, Detroit, Michigan, USA
Am J Hypertens 10:1349-55. 1997..Specific insulin binding was not affected by these two agents. Thus, both captopril and bisoprolol may have favorable but different effects on TK activity and insulin action at the cellular level...- Magnesium metabolism in type 2 diabetes mellitus, metabolic syndrome and insulin resistanceMario Barbagallo
Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
Arch Biochem Biophys 458:40-7. 2007.... - Magnesium metabolism in hypertension and type 2 diabetes mellitusMario Barbagallo
Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
Am J Ther 14:375-85. 2007.... - Magnesium intake in the pathophysiology and treatment of the cardiometabolic syndrome: where are we in 2006?Mario Barbagallo
Department of Geriatrics, Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
J Cardiometab Syndr 1:356-7. 2006 - Quality of life in osteoporotic women with inadequate clinical response to antiresorptive drugs: results from the ICARO studyMario Barbagallo
Division of Geriatrics, Department of Internal Medicine and Emergent Pathologies, University of Palermo, Palermo, Italy
Aging Clin Exp Res 19:24-7. 2007..The aim of the present study was to evaluate the impact of the clinical response to treatment on the health-related quality of life in women with postmenopausal osteoporosis... 
Diagnosing and managing thyroid disease in the nursing homeLigia J Dominguez
Geriatric Unit, Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
J Am Med Dir Assoc 9:9-17. 2008..However, in the long-term setting, the possibility of thyroid dysfunction can be more often investigated, and the consideration of treatment and follow-up is needed to improve quality of life of affected older people...- Blood pressure and cardiovascular risk profiles of Africans who migrate to a Western countryLigia J Dominguez
Geriatric Unit, Department of Clinical Medicine and Emerging Pathologies, University of Palermo, Italy
Ethn Dis 18:512-8. 2008..We conducted a community survey to evaluate cardiovascular risk in Africans who recently migrated to Italy... - Magnesium homeostasis and agingMario Barbagallo
Geriatric Unit, Department of Internal Medicine and Emergent Pathologies, University of Palermo, Italy
Magnes Res 22:235-46. 2009..Mg deficit associated to aging may be at least one of the pathophysiological links that may help to explain the interactions between inflammation and oxidative stress with the aging process and many age-related diseases... - Magnesium and agingM Barbagallo
Mario Barbagallo, MD Viale F Scaduto 6 c, 90144 Palermo, Italy
Curr Pharm Des 16:832-9. 2010.... - Age, homocysteine, and oxidative stress: relation to hypertension and type 2 diabetes mellitusLigia J Dominguez
Geriatric Unit, Department of Clinical Medicine and Emerging Pathologies, University of Palermo, Palermo, Italy
J Am Coll Nutr 29:1-6. 2010..We evaluated these parameters in relation to age and the presence of hypertension and type 2 diabetes mellitus... - Oral magnesium supplementation improves vascular function in elderly diabetic patientsMario Barbagallo
Geriatric Unit, Dept of Internal Medicine and Emergent Pathologies, University of Palermo, Italy
Magnes Res 23:131-7. 2010..9%; p < 0.05). No significant differences were found, either in ion-Mg or endothelial function, in the control group. In conclusion, the present study suggests that oral Mg improves endothelial function in diabetic elderly subjects... - Collagen overglycosylation: a biochemical feature that may contribute to bone qualityLigia J Dominguez
Geriatric Unit, University of Palermo, Palermo, Italy
Biochem Biophys Res Commun 330:1-4. 2005..Specific actions on collagen of drugs used for bone protection should be explored in future studies... - Metabolic syndrome therapy: prevention of vascular injury by antidiabetic agentsLigia J Dominguez
Geriatric Unit, Department of Internal Medicine, University of Palermo, viale F Scaduto 6 c, 90144 Palermo, Italy
Curr Hypertens Rep 7:110-6. 2005..In this article, we review the oral agents used to treat type 2 diabetes and the metabolic syndrome, and their effects on vascular tissue... - [Osteoporosis and diabetes]L J Dominguez
U O di Geriatria, Universita degli Studi di Palermo, Italy
Reumatismo 56:235-41. 2004..A better understanding of these mechanisms may help implement the prevention of fractures in the growing population of mature diabetics... - Effects of glutathione on red blood cell intracellular magnesium: relation to glucose metabolismM Barbagallo
Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
Hypertension 34:76-82. 1999..These data demonstrate a direct action of glutathione both in vivo and in vitro to enhance intracellular magnesium and a clinical linkage between cellular magnesium, GSH/GSSG ratios, and tissue glucose metabolism... - Effects of aging on serum ionized and cytosolic free calcium: relation to hypertension and diabetesM Barbagallo
Institute of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy
Hypertension 34:902-6. 1999..The data also suggest that studies of the aging process should be limited to subjects with normal blood pressure and glucose tolerance... - Protective effects of captopril against ischemic stress: role of cellular MgM Barbagallo
Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
Hypertension 34:958-63. 1999.... - Effects of vitamin E and glutathione on glucose metabolism: role of magnesiumM Barbagallo
Institute of Internal Medicine and Geriatrics University of Palermo, Palermo, Italy
Hypertension 34:1002-6. 1999..78, P=0.003). These data show a clinical link between vitamin E administration, cellular magnesium, GSH/GSSG ratio, and tissue glucose metabolism. Further studies are needed to explore the cellular mechanism(s) of this association... - Cardiovascular risk factors in South America and the CaribbeanL J Dominguez
Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
Ethn Dis 9:468-78. 1999..The agenda of any lifestyle-related disease control program should include the promotion of healthy diet, exercise, and should encourage decreasing tobacco and alcohol usage... - Efficacy and tolerability of lercanidipine in monotherapy in elderly patients with isolated systolic hypertensionM Barbagallo
Institute of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy
Aging (Milano) 12:375-9. 2000..These data indicate that lercanidipine, used as monotherapy once a day, is effective in lowering elevated systolic blood pressure in elderly patients, and is well tolerated... - Altered cellular magnesium responsiveness to hyperglycemia in hypertensive subjectsM Barbagallo
Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
Hypertension 38:612-5. 2001.... - Role of magnesium in insulin action, diabetes and cardio-metabolic syndrome XMario Barbagallo
Institute of Internal Medicine and Geriatrics, University of Palermo, Via F Scaduto 6 C, Palermo, Italy
Mol Aspects Med 24:39-52. 2003..We further suggest that a reduced intracellular Mg concentration might be the missing link helping to explain the epidemiological association between NIDDM and hypertension... - Insulin-mimetic action of vanadate: role of intracellular magnesiumM Barbagallo
Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
Hypertension 38:701-4. 2001.... - [The discovery of insulin: what really happened 80 years ago]L J Dominguez
Istituto di Clinica Medica, Universita degli Studi di Palermo
Ann Ital Med Int 16:155-62. 2001..Collip who has hardly ever been associated with this event, culminated in the discovery of insulin... 
Curcumin, inflammation, ageing and age-related diseasesE Sikora
Laboratory of Molecular Bases of Ageing, Nencki Institute of Experimental Biology, PAS, Warsaw, Poland
Immun Ageing 7:1. 2010..In this review we consider the possibility of the spice curcumin, a powerful antioxidant and anti-inflammatory agent possibly capable of improving the health status of the elderly...- Cardiovascular risk factors in centenariansAntonio Galioto
Geriatric Section, Department of Internal Medicine and Emerging Pathologies, University of Palermo, Viale Fco Scaduto 6 c, 90144 Palermo, Italy
Exp Gerontol 43:106-13. 2008..Cardiovascular risk factors mirror the factors that contribute to longevity. Hence, it is not surprising that these risk factors are less prevalent in centenarians when compared to younger old individuals... - Intermittent intramuscular clodronate therapy: a valuable option for older osteoporotic womenLigia J Dominguez
Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, viale F. Scaduto 6/c, 90144 Palermo, Italy
Age Ageing 34:633-6. 2005 - Therapeutic options in osteoporosisLigia J Dominguez
Geriatric Unit, Department of Clinical Medicine and Emergent Pathologies, University of Palermo, Italy
Acta Biomed 81:55-65. 2010..This article reviews the available nonpharmacologic and pharmacologic interventions -proved to be effective- that may be implemented to reduce the risk of osteoporotic fractures... - Azithromycin in an older woman with diabetic gastroparesisLoredana Sutera
Geriatric Unit, Post Graduate School of Geriatrics, University of Palermo, Italy
Am J Ther 15:85-8. 2008.... - Glucose control in the older patient: from intensive, to effective and safeLigia J Dominguez
University of Palermo, Palermo, Italy
Aging Clin Exp Res 22:274-80. 2010..The use of agents with a good safety profiles and with the least possibility of causing hypoglycemia is warranted... - Physiology of the aging bone and mechanisms of action of bisphosphonatesLigia J Dominguez
Geriatric Unit, Department of Internal Medicine and Specialties, University of Palermo, viale F Scaduto 6 c, 90144, Palermo, Italy
Biogerontology 12:397-408. 2011..g., risedronate) may allow better access to osteocyte network. Effects of BPs on bone senescence, cancer cells apoptosis and prevention of cardiovascular calcifications may open new avenues for biogerontological research... - Altered ionized magnesium levels in mild-to-moderate Alzheimer's diseaseMario Barbagallo
Chair of Geriatrics, Department of Internal Medicine and Medical Specialties DIMIS, University of Palermo, Italy
Magnes Res 24:S115-21. 2011..24 p<0.05), while no significant correlations were found in this group of patients between magnesium and ADL or IADL. Our results show the presence of subclinical alterations in Mg-ion in patients with mild to moderate AD... - Magnesium and muscle performance in older persons: the InCHIANTI studyLigia J Dominguez
Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy
Am J Clin Nutr 84:419-26. 2006..8 +/- 0.5, P < 0.0001). CONCLUSIONS: The serum magnesium concentration is an independent correlate of muscle performance in older persons. Whether magnesium supplementation improves muscle function remains to be shown... - Serum ionized magnesium levels in relation to metabolic syndrome in type 2 diabetic patientsFrancesco Corica
Department of Internal Medicine, University of Messina, Messina, Italy
J Am Coll Nutr 25:210-5. 2006..68) were independently associated with hypomagnesemia. CONCLUSIONS: Hypomagnesemia is highly prevalent in diabetic outpatients. High plasma triglycerides, waist circumference and albuminuria are independent correlates of hypomagnesemia... - Anti-aging medicine: pitfalls and hopesLigia J Dominguez
Geriatric Unit, Department of Clinical Medicine and Emerging Pathologies, University of Palermo, Palermo, Italy
Aging Male 12:13-20. 2009..This article reviews some of these advances and places the extravagant claims of anti-aging medicine in perspective. We conclude that a balanced diet of moderate proportions and exercise remain today the only proven fountain of youth... - The cardiometabolic syndrome and sarcopenic obesity in older personsLigia J Dominguez
Geriatric Unit, Department of Internal Medicine, University of Palermo, Italy
J Cardiometab Syndr 2:183-9. 2007..A better understanding of the pathophysiologic mechanisms of sarcopenic obesity may help to elucidate the complex relationship between CMS and mortality/morbidity in older adults... - Combination of intensive cognitive rehabilitation and donepezil therapy in Alzheimer's disease (AD)Marcello Giordano
Alzheimer Center, Division of Geriatrics, Ospedale Ingrassia, ASP di Palermo, Palermo, Via La Loggia 5, 90100 Palermo, Italy
Arch Gerontol Geriatr 51:245-9. 2010..Our results suggest benefit of an intensive ROT program in dementia patients receiving donepezil that seems to be maintained as far as ROT is continued by the caregiver... - Systemic immune responses in Alzheimer's disease: in vitro mononuclear cell activation and cytokine productionMariavaleria Pellicano
Dipartimento di Biopatologia e Biotecnologie Mediche e Forensi, Universita di Palermo, Palermo, Italy
J Alzheimers Dis 21:181-92. 2010..These results support the involvement of systemic immunity in AD patients. However, our study is an observational one so we cannot draw a conclusion about its contribution to the pathophysiology of the disease...