M L Barbaccia

Summary

Affiliation: University of Rome Tor Vergata
Country: Italy

Publications

  1. ncbi request reprint Plasma 5alpha-androstane-3alpha,17betadiol, an endogenous steroid that positively modulates GABA(A) receptor function, and anxiety: a study in menopausal women
    M L Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata, Via Tor Vergata 135, 00133, Rome, Italy
    Psychoneuroendocrinology 25:659-75. 2000
  2. ncbi request reprint Clozapine, but not haloperidol, increases brain concentrations of neuroactive steroids in the rat
    M L Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata, Rome, Italy
    Neuropsychopharmacology 25:489-97. 2001
  3. ncbi request reprint GABA(B) receptor-mediated increase of neurosteroids by gamma-hydroxybutyric acid
    M L Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata, Via Tor Vergata 135, 00133 Rome, Italy
    Neuropharmacology 42:782-91. 2002
  4. ncbi request reprint Neurosteroidogenesis: relevance to neurosteroid actions in brain and modulation by psychotropic drugs
    Maria Luisa Barbaccia
    Department of Neuroscience, Section of Pharmacology, University of Rome Tor Vergata Schoool of Medicine, Via Montpellier, 1, 00133 Rome, Italy
    Crit Rev Neurobiol 16:67-74. 2004
  5. ncbi request reprint Endogenous gamma-aminobutyric acid (GABA)(A) receptor active neurosteroids and the sedative/hypnotic action of gamma-hydroxybutyric acid (GHB): a study in GHB-S (sensitive) and GHB-R (resistant) rat lines
    Maria Luisa Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata, Via Montpellier, 1, 00133 Rome, Italy
    Neuropharmacology 49:48-58. 2005
  6. ncbi request reprint Cognitive impairment and increased brain neurosteroids in adult rats perinatally exposed to low millimolar blood alcohol concentrations
    Maria Luisa Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata Medical School, Via Montpellier 1, 00133 Rome, Italy
    Psychoneuroendocrinology 32:931-42. 2007
  7. doi request reprint Much excitement about antidepressants, DBI and c-FOS
    Maria Luisa Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata, Via Montpellier, 1 00133 Rome, Italy
    Pharmacol Res 64:333-5. 2011
  8. ncbi request reprint Stress and neuroactive steroids
    M L Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata, 00133 Rome, Italy
    Int Rev Neurobiol 46:243-72. 2001

Detail Information

Publications8

  1. ncbi request reprint Plasma 5alpha-androstane-3alpha,17betadiol, an endogenous steroid that positively modulates GABA(A) receptor function, and anxiety: a study in menopausal women
    M L Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata, Via Tor Vergata 135, 00133, Rome, Italy
    Psychoneuroendocrinology 25:659-75. 2000
    ..These data suggest that endogenous 3alpha-ADIOL modulates the central GABAergic tone and that higher 3alpha-ADIOL concentrations could have a role in preventing the expression of anxiety in the asymptomatic women...
  2. ncbi request reprint Clozapine, but not haloperidol, increases brain concentrations of neuroactive steroids in the rat
    M L Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata, Rome, Italy
    Neuropsychopharmacology 25:489-97. 2001
    ..These results suggest that the clozapine-induced increases in neuroactive steroid concentrations in the brain may contribute to the atypical pharmacological profile of this antipsychotic drug...
  3. ncbi request reprint GABA(B) receptor-mediated increase of neurosteroids by gamma-hydroxybutyric acid
    M L Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata, Via Tor Vergata 135, 00133 Rome, Italy
    Neuropharmacology 42:782-91. 2002
    ....
  4. ncbi request reprint Neurosteroidogenesis: relevance to neurosteroid actions in brain and modulation by psychotropic drugs
    Maria Luisa Barbaccia
    Department of Neuroscience, Section of Pharmacology, University of Rome Tor Vergata Schoool of Medicine, Via Montpellier, 1, 00133 Rome, Italy
    Crit Rev Neurobiol 16:67-74. 2004
    ....
  5. ncbi request reprint Endogenous gamma-aminobutyric acid (GABA)(A) receptor active neurosteroids and the sedative/hypnotic action of gamma-hydroxybutyric acid (GHB): a study in GHB-S (sensitive) and GHB-R (resistant) rat lines
    Maria Luisa Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata, Via Montpellier, 1, 00133 Rome, Italy
    Neuropharmacology 49:48-58. 2005
    ..These results suggest that the GHB-induced increases of brain 3alpha,5alpha-THP and 3alpha,5alpha-THDOC concentrations are implicated in the eliciting of the sedative/hypnotic action of GHB...
  6. ncbi request reprint Cognitive impairment and increased brain neurosteroids in adult rats perinatally exposed to low millimolar blood alcohol concentrations
    Maria Luisa Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata Medical School, Via Montpellier 1, 00133 Rome, Italy
    Psychoneuroendocrinology 32:931-42. 2007
    ..It is speculated that, by inducing a greater amplification of GABA(A) receptor function, the elevation of 3alpha,5alpha-THP brain content contributes to the cognitive impairment exhibited by adult alcohol-exposed offspring...
  7. doi request reprint Much excitement about antidepressants, DBI and c-FOS
    Maria Luisa Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata, Via Montpellier, 1 00133 Rome, Italy
    Pharmacol Res 64:333-5. 2011
    ....
  8. ncbi request reprint Stress and neuroactive steroids
    M L Barbaccia
    Department of Neuroscience, University of Rome Tor Vergata, 00133 Rome, Italy
    Int Rev Neurobiol 46:243-72. 2001
    ..This chapter summarizes observations from our laboratories and others, suggesting that neurosteroids and GABAergic transmission are important contributors to the changes in emotional state induced by environmental stress...