C Azzari

Summary

Affiliation: University of Florence
Country: Italy

Publications

  1. ncbi request reprint Cost of varicella-related hospitalisations in an Italian paediatric hospital: comparison with possible vaccination expenses
    C Azzari
    Paediatric Immunology Unit, Anna Meyer Children s Hospital and University of Florence, Florence, Italy
    Curr Med Res Opin 23:2945-54. 2007
  2. ncbi request reprint Higher risk of hepatitis C virus perinatal transmission from drug user mothers is mediated by peripheral blood mononuclear cell infection
    Chiara Azzari
    Department of Pediatrics, University of Florence, Anna Meyer Children s Hospital, Florence, Italy
    J Med Virol 80:65-71. 2008
  3. pmc Molecular detection methods and serotyping performed directly on clinical samples improve diagnostic sensitivity and reveal increased incidence of invasive disease by Streptococcus pneumoniae in Italian children
    Chiara Azzari
    Department of Paediatrics, University of Florence and Anna Meyer Children s Hospital, Viale Pieraccini 24, Florence I 50139, Italy
    J Med Microbiol 57:1205-12. 2008
  4. pmc Pneumococcal DNA is not detectable in the blood of healthy carrier children by real-time PCR targeting the lytA gene
    Chiara Azzari
    Department of Paediatrics, Anna Meyer Children s University Hospital, Florence, Italy
    J Med Microbiol 60:710-4. 2011
  5. doi request reprint Neonatal screening for severe combined immunodeficiency caused by an adenosine deaminase defect: a reliable and inexpensive method using tandem mass spectrometry
    Chiara Azzari
    Department of Pediatrics, University of Florence, Florence, Italy
    J Allergy Clin Immunol 127:1394-9. 2011
  6. ncbi request reprint TT virus infection in human immunodeficiency virus type 1 infected mothers and their infants
    M De Martino
    Department of Paediatrics, University of Florence, Florence, Italy
    J Med Virol 61:347-51. 2000
  7. ncbi request reprint Vertical hepatitis C virus transmission is not related to mother-child class-1 HLA concordance
    C Azzari
    Department of Paediatrics, University of Florence, Anna Meyer Children s Hospital, Florence, Italy
    Int J Immunopathol Pharmacol 20:827-31. 2007
  8. ncbi request reprint SEN virus co-infection among HCV-RNA-positive mothers, risk of transmission to the offspring and outcome of child infection during a 1-year follow-up
    M Moriondo
    Department of Paediatrics, University of Florence, Italy and Paediatric Hospital Anna Meyer, Florence, Italy
    J Viral Hepat 14:355-9. 2007
  9. ncbi request reprint Allergen specific nasal challenge to latex in children with latex allergy: clinical and immunological evaluation
    R Bernardini
    Pediatric Allergy and Pulmonology Center, Department of Pediatrics, University of Florence, Anna Meyer Children s Hospital, Via Luca Giordano 13, Florence, Italy
    Int J Immunopathol Pharmacol 21:333-41. 2008
  10. ncbi request reprint Restored antioxidant capacity parallels the immunologic and virologic improvement in children with perinatal human immunodeficiency virus infection receiving highly active antiretroviral therapy
    M De Martino
    Department of Pediatrics, University of Florence, Florence, Italy
    Clin Immunol 100:82-6. 2001

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Cost of varicella-related hospitalisations in an Italian paediatric hospital: comparison with possible vaccination expenses
    C Azzari
    Paediatric Immunology Unit, Anna Meyer Children s Hospital and University of Florence, Florence, Italy
    Curr Med Res Opin 23:2945-54. 2007
    ....
  2. ncbi request reprint Higher risk of hepatitis C virus perinatal transmission from drug user mothers is mediated by peripheral blood mononuclear cell infection
    Chiara Azzari
    Department of Pediatrics, University of Florence, Anna Meyer Children s Hospital, Florence, Italy
    J Med Virol 80:65-71. 2008
    ..Peripheral blood mononuclear cell infection represents one of the most important risk factors for hepatitis C virus perinatal transmission...
  3. pmc Molecular detection methods and serotyping performed directly on clinical samples improve diagnostic sensitivity and reveal increased incidence of invasive disease by Streptococcus pneumoniae in Italian children
    Chiara Azzari
    Department of Paediatrics, University of Florence and Anna Meyer Children s Hospital, Viale Pieraccini 24, Florence I 50139, Italy
    J Med Microbiol 57:1205-12. 2008
    ..Real-time PCR and multiplex sequential PCR can be used directly on biological samples, improving the ability to diagnose IPD. The incidence of IPD appears 5-10 times higher by PCR than by cultural methods...
  4. pmc Pneumococcal DNA is not detectable in the blood of healthy carrier children by real-time PCR targeting the lytA gene
    Chiara Azzari
    Department of Paediatrics, Anna Meyer Children s University Hospital, Florence, Italy
    J Med Microbiol 60:710-4. 2011
    ..Its sensitivity, which surpasses that of other methods for this purpose, does not come at the cost of reduced specificity...
  5. doi request reprint Neonatal screening for severe combined immunodeficiency caused by an adenosine deaminase defect: a reliable and inexpensive method using tandem mass spectrometry
    Chiara Azzari
    Department of Pediatrics, University of Florence, Florence, Italy
    J Allergy Clin Immunol 127:1394-9. 2011
    ..ADA-SCID complies with all the criteria for inclusion in a newborn screening program. However, screening methods are still expensive or provide a non-negligible number of indeterminate results...
  6. ncbi request reprint TT virus infection in human immunodeficiency virus type 1 infected mothers and their infants
    M De Martino
    Department of Paediatrics, University of Florence, Florence, Italy
    J Med Virol 61:347-51. 2000
    ..TTV infection in HIV 1 infected women is prevalently related to intravenous drug user. The findings suggest that infants may acquire TTV at birth. Infection may persist without evident liver disease...
  7. ncbi request reprint Vertical hepatitis C virus transmission is not related to mother-child class-1 HLA concordance
    C Azzari
    Department of Paediatrics, University of Florence, Anna Meyer Children s Hospital, Florence, Italy
    Int J Immunopathol Pharmacol 20:827-31. 2007
    ..30) and when only A and B alleles were evaluated (p=0.59). Mother-infant HLA concordance does not affect HCV vertical transmission...
  8. ncbi request reprint SEN virus co-infection among HCV-RNA-positive mothers, risk of transmission to the offspring and outcome of child infection during a 1-year follow-up
    M Moriondo
    Department of Paediatrics, University of Florence, Italy and Paediatric Hospital Anna Meyer, Florence, Italy
    J Viral Hepat 14:355-9. 2007
    ..Persistence of SENV infection was demonstrated in 100% of infected children after 1-year follow-up, but none had clinical evidence of liver disease...
  9. ncbi request reprint Allergen specific nasal challenge to latex in children with latex allergy: clinical and immunological evaluation
    R Bernardini
    Pediatric Allergy and Pulmonology Center, Department of Pediatrics, University of Florence, Anna Meyer Children s Hospital, Via Luca Giordano 13, Florence, Italy
    Int J Immunopathol Pharmacol 21:333-41. 2008
    ..MFNS premedication before an ASNCL may prevent some immunological responses induced by ASNCL without clinical allergic modifications...
  10. ncbi request reprint Restored antioxidant capacity parallels the immunologic and virologic improvement in children with perinatal human immunodeficiency virus infection receiving highly active antiretroviral therapy
    M De Martino
    Department of Pediatrics, University of Florence, Florence, Italy
    Clin Immunol 100:82-6. 2001
    ..A positive feedback may be triggered since restored antioxidant capacity counterbalances the oxidative stress, which enhances lymphocyte apoptosis and HIV replication...
  11. ncbi request reprint Characterization and sorting of flow cytometric populations in human semen
    S Marchiani
    Sexual Medicine and Andrology Unit, Department of Experimental, Clinical and Biomedical Sciences, Center of Excellence DeNothe, University of Florence, Florence, Italy
    Andrology 2:394-401. 2014
    ..4 ± 19.8%; CMA3: 36.1 ± 18.0%). Hence, the role of apoptosis in generating dimmer spermatozoa and their DNA fragmentation appears clear, whereas the involvement of defects during the chromatin packaging remains elusive...
  12. ncbi request reprint Lack of transmission of TT virus through immunoglobulins
    C Azzari
    Pediatric Clinic III, University of Florence, and the A Meyer Pediatric Hospital, Florence, Italy
    Transfusion 41:1505-8. 2001
    ..Viral DNA was demonstrated in commercial preparations of FVIII and F IX, but very few data have been reported on immunoglobulins. The risk of TTV infection associated with intramuscular or IV immunoglobulin administration is unclear...
  13. ncbi request reprint Bcgitis and vaccine-derived poliovirus infection in a patient with a novel deletion in RAG1 binding site
    C Canessa
    Immunology Department, Anna Meyer Children s Hospital, Florence, Italy
    Int J Immunopathol Pharmacol 26:511-5. 2013
    ..A neonatal screening program for SCID would identify affected infants at birth, before live vaccines are administered...
  14. ncbi request reprint Hospitalization rates of complicated pneumococcal community-acquired pneumonia is increasing in Tuscan children
    F Bonsignori
    Department of Sciences for Woman and Child s Health, Anna Meyer Children s University Hospital, Florence, Italy
    Int J Immunopathol Pharmacol 26:995-1005. 2013
    ..41 in 2009 per 100,000 children) over the study period were highlighted. Our epidemiological data confirm the decision to introduce the PCV13 vaccine, to satisfy the need to prevent a wider group of pneumococcal serotypes. ..
  15. ncbi request reprint Streptococcus pneumoniae: elusive mechanisms of the body's defense systems
    T Bondi
    Department of Pediatrics, University of Florence, Florence, Italy
    J Prev Med Hyg 53:89-93. 2012
    ....
  16. ncbi request reprint Urticaria and urticaria related skin condition/disease in children
    E Novembre
    Department of Pediatrics, University of Florence, Italy
    Eur Ann Allergy Clin Immunol 40:5-13. 2008
    ..When urticaria is associated to anaphylaxis, i.m epinephrine needs to be used, together with antihistamines and steroids (in addition to fluids and bronchodilatators if required)...
  17. ncbi request reprint CD4+CD25+Foxp3+ T regulatory cells are not involved in oral desensitization
    F Mori
    Allergy and Clinical Immunological Unit, A Meyer Children Hospital, Department of Pediatrics, University of Florence, Italy
    Int J Immunopathol Pharmacol 23:359-61. 2010
    ....
  18. doi request reprint Development of a specific method to evaluate 8-hydroxy, 2-deoxyguanosine in sperm nuclei: relationship with semen quality in a cohort of 94 subjects
    M Cambi
    Andrology Unit, Department of Clinical Physiopathology, University of Florence, Viale Pieraccini 6, I 50139 Florence, Italy
    Reproduction 145:227-35. 2013
    ....
  19. ncbi request reprint Evidence of subclinical intestinal inflammation by 99m technetium leukocyte scintigraphy in patients with HLA-B27 positive juvenile onset active spondyloarthropathy
    P Lionetti
    Department of Pediatrics, University of Florence, Italy
    J Rheumatol 27:1538-41. 2000
    ....
  20. doi request reprint Respiratory impedance and bronchodilator response in healthy Italian preschool children
    C Calogero
    Section of Respiratory Medicine, Department of Paediatrics, University of Florence, Anna Meyer University Hospital for Children, Florence, Italy
    Pediatr Pulmonol 45:1086-94. 2010
    ..To define normal values for respiratory resistance (R(rs)) and reactance (X(rs)) and bronchodilator response (BDR) in a population of healthy Italian preschool children using a commercially available forced oscillation device...
  21. pmc Highly active antiretroviral therapy restores in vitro mitogen and antigen-specific T-lymphocyte responses in HIV-1 perinatally infected children despite virological failure
    M Peruzzi
    Laboratory of Immunology, Department of Paediatrics, University of Florence, Italy
    Clin Exp Immunol 128:365-71. 2002
    ..It implies that a direct mechanism might be involved in the overall immune recovery under HAART...
  22. ncbi request reprint Reduction of bcl-2 in T cells during immunosuppressive therapy in patients with severe juvenile onset systemic lupus erythematosus
    F Falcini
    Rheumatology Unit, University of Florence, Florence, 50132, Italy
    Clin Immunol 93:59-64. 1999
    ..Our data show a strong correlation between bcl-2 protein expression and disease activity and suggest an alteration of apoptotic regulation in JSLE patients...
  23. ncbi request reprint The immunity of upper airways
    C Canessa
    Department of Pediatrics, University of Florence Anna Meyer Children Hospital, Italy
    Int J Immunopathol Pharmacol 23:8-12. 2010
    ..The NALT has a major role as regards to the infectious diseases of this area, which are the most common in children. It is also an interesting field of experimentation for new vaccine strategies in the future...
  24. ncbi request reprint Severe necrotizing pneumonia complicating influenza A (H1N1): the role of immunologic interaction
    R Guidi
    Department of Pediatrics, Azienda Ospedaliero Universitaria, Salesi Children and x0027 s Hospital, Ancona, Italy
    Int J Immunopathol Pharmacol 24:1093-7. 2011
    ..The role of modern molecular techniques in improving diagnostic microbiology sensitivity and informing consequent clinical care is emphasized...
  25. ncbi request reprint Inhibition of natural killer cell cytotoxicity and interferon gamma production by the envelope protein of HIV and prevention by vasoactive intestinal peptide
    M Peruzzi
    Department of Pediatrics, University of Florence, Italy
    AIDS Res Hum Retroviruses 16:1067-73. 2000
    ....
  26. ncbi request reprint Acute febrile cholestasis as an inaugural manifestation of Kawasaki's disease
    F Falcini
    Rheumatology Unit, University of Florence, Florence, Italy
    Clin Exp Rheumatol 18:779-80. 2000
    ..We conclude that this syndrome should be suspected in any child with febrile cholestasis of unknown origin, in order that coronary involvement may be prevented by the administration of IVGG...
  27. ncbi request reprint Diagnostic value of three different latex extracts
    R Bernardini
    Pediatric Allergy and Pulmonology Center, Department of Pediatrics, Anna Meyer Children Hospital, University of Florence, Italy
    Int J Immunopathol Pharmacol 20:393-400. 2007
    ..This study showed that SL extract is able to express the best in vitro and in vivo diagnostic potential. Thus, its use should be preferred for the diagnosis of patients affected by latex allergy...
  28. ncbi request reprint Alanine transaminase levels in the year before pregnancy predict the risk of hepatitis C virus vertical transmission
    Giuseppe Indolfi
    Department of Pediatrics, University of Florence, Anna Meyer Children s Hospital, Florence, Italy
    J Med Virol 78:911-4. 2006
    ..ALT determination, a simple, widely available and inexpensive test, may help in identifying mothers with an increased risk of HCV vertical transmission...
  29. doi request reprint Intrafamilial transmission of hepatitis C virus: infection of the father predicts the risk of perinatal transmission
    Giuseppe Indolfi
    Department of Paediatrics, University of Florence, Anna Meyer Children s Hospital, Florence, Italy
    J Med Virol 80:1907-11. 2008
    ..HCV infection of the father seems to be associated with perinatal transmission but this relationship is dependent on maternal history of intravenous drug use...
  30. ncbi request reprint Injection drug use facilitates hepatitis C virus infection of peripheral blood mononuclear cells
    Massimo Resti
    Department of Pediatrics, University of Florence, and Pediatric Hospital A Meyer, I 50132 Florence, Italy
    Clin Infect Dis 35:236-9. 2002
    ..00003). No correlation was found between infection of the PBMCs and HCV genotype or virus load. Route of transmission and viral factors, as well as immunologic dysfunction, may play a role in viral tropism...
  31. ncbi request reprint Maternal drug use is a preeminent risk factor for mother-to-child hepatitis C virus transmission: results from a multicenter study of 1372 mother-infant pairs
    Massimo Resti
    Pediatric Clinic III, University of Florence and Pediatric Hospital A Meyer, Via Luca Giordano 13, I 50132 Florence, Italy
    J Infect Dis 185:567-72. 2002
    ..51; 95% CI, 1.19-1.92; P =.0006), but no association was found with HIV-1 coinfection (AOR, 0.98; 95% CI, 0.73-1.33; P =.93). IDU, but not HIV-1 coinfection, seems to be a preeminent risk factor for vertical HCV transmission...
  32. ncbi request reprint Mother-to-infant transmission of multiple blood-borne viral infections from multi-infected mothers
    Giuseppe Indolfi
    Department of Paediatrics, University of Florence, Anna Meyer Children s Hospital, Florence, Italy
    J Med Virol 79:743-7. 2007
    ..These observations may be of clinical relevance in perinatal counseling...
  33. ncbi request reprint Neprilysin levels in plasma and synovial fluid of juvenile idiopathic arthritis patients
    Gabriele Simonini
    Rheumatology Unit, Department of Pediatrics, University of Florence, Via Pico della Mirandola 24, 50132 Florence, Italy
    Rheumatol Int 25:336-40. 2005
    ..In 20 subjects requiring local steroid injection, NEP was measured in synovial fluid...
  34. ncbi request reprint Clinical features and progression of perinatally acquired hepatitis C virus infection
    Massimo Resti
    Department of Paediatrics and Paediatric Hospital A Meyer, Florence, Italy
    J Med Virol 70:373-7. 2003
    ..The chronic progression rate of infection is high, but the associated liver disease is usually mild. High ALT levels at onset seem to offer greater opportunity of biochemical remission and loss of viremia during follow-up...
  35. ncbi request reprint Hepatitis C virus infection in children coinfected with HIV: epidemiology and management
    Massimo Resti
    Department of Pediatrics, University of Florence, Florence, Italy
    Paediatr Drugs 4:571-80. 2002
    ..At present, treating HIV disease and monitoring HCV infection and hepatotoxicity induced by antiretroviral drugs seem to be the more reasonable approach to HCV/HIV coinfection in childhood...
  36. ncbi request reprint Clinical, immunological, and molecular analysis in a large cohort of patients with X-linked agammaglobulinemia: an Italian multicenter study
    Alessandro Plebani
    Dipartimento di Pediatria, Universita di Brescia, Italy
    Clin Immunol 104:221-30. 2002
    ..Sistemic infections such as sepsis and meningitis/meningoencephalitis decreased over follow-up, probably due to optimal protection provided by high circulating IgG levels reached with IVIG...
  37. ncbi request reprint Chronic hepatitis C virus infection in childhood: clinical patterns and evolution in 224 white children
    Paloma Jara
    Hospital Infantil La Paz, Madrid, Spain
    Clin Infect Dis 36:275-80. 2003
    ..Conversely, the higher rates of fibrosis observed in older patients suggest the possibility of an insidious progression of HCV-associated liver disease...
  38. ncbi request reprint Interleukin-7 and immunologic failure despite treatment with highly active antiretroviral therapy in children perinatally infected with HIV-1
    Elena Chiappini
    Division of Pediatrics and Infectious Diseases, Department of Pediatrics, University of Florence, Florence, Italy
    J Acquir Immune Defic Syndr 33:601-4. 2003
    ....
  39. ncbi request reprint Selective deficiency of naïve CD4+ T-lymphocytes in a child with congenital lymphoedema
    Elena Chiappini
    Division of Paediatrics and Infectious Diseases, Department of Paediatrics, University of Florence, Via Luca Giordano 13, 50132 Florence, Italy
    Eur J Pediatr 162:752-4. 2003
    ..A high proportion of naïve CD4+ T-lymphocytes was found in the ascitic fluid, supporting the hypothesis of extra-vascular sequestration of these cells into lymphoedematous tissue...
  40. pmc Defective regulatory and effector T cell functions in patients with FOXP3 mutations
    Rosa Bacchetta
    San Raffaele Telethon Institute for Gene Therapy HSR TIGET, Milan, Italy
    J Clin Invest 116:1713-22. 2006
    ....
  41. doi request reprint Reduction of carriage and transmission of Streptococcus pneumoniae: the beneficial "side effect" of pneumococcal conjugate vaccine
    Chiara Azzari
    Clin Infect Dis 47:997-9. 2008
  42. ncbi request reprint Can hexavalent vaccines be simultaneously administered with pneumococcal or meningococcal conjugate vaccines?
    Alberto E Tozzi
    Bambino Gesu Hospital, Rome, Italy
    Hum Vaccin 3:252-9. 2007
    ..We reviewed the available literature to assess the effects on immunogenicity and safety of simultaneous administration of hexavalent and conjugate pneumococcal and meningococcal C vaccines in healthy children...
  43. ncbi request reprint Clinical features, long-term follow-up and outcome of a large cohort of patients with Chronic Granulomatous Disease: an Italian multicenter study
    Baldassarre Martire
    Dipartimento di Biomedicina dell Eta Evolutiva, Universita di Bari, Italy
    Clin Immunol 126:155-64. 2008
    ..No evidence justifying long-term prophylaxis with IFNgamma was obtained...