Research Topics
Species | Sofia AsioliSummaryAffiliation: University of Turin Country: Italy Publications
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Detail Information
Publications
Papillary thyroid carcinoma with hobnail features: histopathologic criteria to predict aggressive behaviorSofia Asioli
Department of Biomedical Sciences and Human Oncology, University of Turin, 10126 Italy
Hum Pathol 44:320-8. 2013..Tumors with more than 30% hobnail/micropapillary features were often very aggressive, although 2 patients with tumors with 10% hobnail/micropapillary features also had poor outcomes...
Expression of p63 is the sole independent marker of aggressiveness in localised (stage I-II) Merkel cell carcinomasSofia Asioli
Department of Biomedical Sciences and Human Oncology, University of Torino, Torino, Italy
Mod Pathol 24:1451-61. 2011..0001). The present data indicate that p63 expression is associated with a worse prognosis in patients with Merkel cell carcinoma, and in localised tumours it represents the single independent predictor of clinical evolution...
Emerin immunohistochemistry reveals diagnostic features of nuclear membrane arrangement in thyroid lesionsSofia Asioli
Department of Biomedical Sciences and Oncology, University of Turin, Turin, Italy
Histopathology 54:571-9. 2009..The aim was to focus on the immunohistochemistry of emerin, a protein of the NM whose decoration best demarcates the nuclear shape...
Cytological detection of papillary thyroid carcinomas by nuclear membrane decoration with emerin stainingSofia Asioli
Department of Biomedical Sciences and Human Oncology, Molinette Hospital, University of Turin, Via Santena 7, 10126, Turin, Italy
Virchows Arch 457:43-51. 2010....
The pre-lymphatic pathway, the rooths of the lymphatic system in breast tissue: a 3D studySofia Asioli
Department of Biomedical Sciences and Human Oncology, Molinette Hospital, University of Turin, Via Santena 7, 10126, Turin, Italy
Virchows Arch 453:401-6. 2008..The present findings suggest that the existence of pre-lymphatics has to be taken in consideration in the intramammary spread of malignant tumours...
Merits of the PMiT (papillary microtumor) terminology in the definition of a subset of incidental papillary microcarcinomas of the thyroidSofia Asioli
Department of Biomedical Sciences and Oncology, University of Turin, Turin, Italy
Int J Surg Pathol 17:378-83. 2009....
Poorly differentiated carcinoma of the thyroid: validation of the Turin proposal and analysis of IMP3 expressionSofia Asioli
Division of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Mod Pathol 23:1269-78. 2010..Expression of IMP3 appears to be an adverse prognostic factor for poorly differentiated thyroid carcinoma...
p63 expression as a new prognostic marker in Merkel cell carcinomaSofia Asioli
Department of Biomedical Sciences and Human Oncology, University of Turin, Italy
Cancer 110:640-7. 2007..Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin tumor, mostly affecting elderly individuals. The histogenesis of this rare tumor as well as its prognostic criteria are a matter of dispute...
"Benign" metastatic meningioma: clinico-pathological analysis of one case metastasising to the lung and overview on the concepts of either primitive or metastatic meningiomas of the lungSofia Asioli
Department of Biomedical Sciences and Human Oncology Molinette Hospital, University of Turin, Via Santena 7, 10100, Turin, Italy
Virchows Arch 450:591-4. 2007..They represent a typical example of "benign" tumours that may implant to the lung similar to other tumours, definitely considered benign but reported to rarely present unusual secondary localization...
Clinical significance of tumor-infiltrating lymphocytes in lung neoplasmsEnrico Ruffini
Department of Thoracic Surgery, University of Torino, Torino, Italy
Ann Thorac Surg 87:365-71; discussion 371-2. 2009..We examined prevalence, correlations, and prognostic significance of TIL among our patient population of resected lung neoplasms...
Histone deacetylase inhibition modulates E-cadherin expression and suppresses migration and invasion of anaplastic thyroid cancer cellsMaria Graziella Catalano
Department of Clinical Pathophysiology, University of Turin, 10126 Torino, Italy
J Clin Endocrinol Metab 97:E1150-9. 2012..Epigenetic silencing is considered one of the leading mechanisms of E-cadherin impairment, which causes the acquisition of the invasive and metastatic phenotype of anaplastic thyroid cancer...
Significance of the presence of microscopic vascular invasion after complete resection of Stage I-II pT1-T2N0 non-small cell lung cancer and its relation with T-Size categories: did the 2009 7th edition of the TNM staging system miss something?Enrico Ruffini
Division of Thoracic Surgery, University of Torino, Torino, Italy
J Thorac Oncol 6:319-26. 2011....
Solid cell nests in Hashimoto's thyroiditis sharing features with papillary thyroid microcarcinomaSofia Asioli
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Endocr Pathol 20:197-203. 2009..These histological and immunophenotypic features can be used to distinguish SCN from papillary thyroid microcarcinomas associated with Hashimoto's thyroiditis...
Papillary thyroid carcinoma with prominent hobnail features: a new aggressive variant of moderately differentiated papillary carcinoma. A clinicopathologic, immunohistochemical, and molecular study of eight casesSofia Asioli
Department of Laboratory Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Surg Pathol 34:44-52. 2010..Two patients are alive without disease after 120 and 236 months. PTC with a prominent hobnail pattern is a moderately differentiated PTC variant with aggressive clinical behavior and significant mortality...
Approaching heterogeneity of human epidermal growth factor receptor 2 in surgical specimens of gastric cancerSofia Asioli
Department of Biomedical Sciences and Human Oncology, University of Turin, and Onco Haematological Department, Oncology Unit, S Giovanni Battista Hospital, 10126 Turin, Italy
Hum Pathol 43:2070-9. 2012..57). In conclusion, testing more than 1 tissue block of cancer from specimens of gastric resection provides a more reliable human epidermal growth factor receptor 2 assessment regardless of the antibody used...
Radical resection of a giant, invasive and symptomatic malignant Solitary Fibrous Tumour (SFT) of the pleuraPier Luigi Filosso
University of Torino Italy, Department of Thoracic Surgery, San Giovanni Battista Hospital, Via Genova, 3, 10126 Torino, Italy
Lung Cancer 64:117-20. 2009..The case of a giant, invasive, radically resected malignant SFT, is described. The role of postoperative radiotherapy, to reduce the risk of recurrence, is also discussed...
Tumor staging but not grading is associated with adverse clinical outcome in neuroendocrine tumors of the appendix: a retrospective clinical pathologic analysis of 138 casesMarco Volante
Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy
Am J Surg Pathol 37:606-12. 2013....
Metastasis of malignant peritoneal epithelioid mesothelioma in endoscopic gastric biopsy: a diagnostic pitfallLorenzo Daniele
Department of Biomedical Sciences and Human Oncology, University of Turin, Turin, Italy
Int J Surg Pathol 19:217-9. 2011....
Diagnosis of biliary tract lesions by histological sectioning of brush bristles as alternative to cytological smearingSofia Asioli
Department of Biomedical Sciences and Human Oncology, Molinette Hospital, University of Turin, Turin, Italy
Am J Gastroenterol 103:1274-81. 2008..To increase the diagnostic potential of endoscopic biliary tract brushing, we devised an approach alternative to cytological smearing, leading to the preoperative histological examination of the collected material...
Endoscopic Saphenous harvesting with an Open CO2 System (ESOS) trial for coronary artery bypass grafting surgery: study protocol for a randomized controlled trialAntonio Campanella
Thoracic and Cardiovascular Department, Division of Cardiac Surgery, San Giovanni Battista of Turin Hospital, University of Turin, Corso Bramante 84, 10126 Turin, Italy
Trials 12:243. 2011..However, to date the short and the long-term benefits of the endoscopic technique remain controversial. This study provides an interesting opportunity to address this gap in the literature...
Goblet cell carcinoids and other mixed neuroendocrine/nonneuroendocrine neoplasmsMarco Volante
Department of Clinical and Biological Sciences, University of Turin and San Luigi Hospital, Regione Gonzole10, 10043, Orbassano, Torino, Italy
Virchows Arch 451:S61-9. 2007..Moreover, molecular and clinical aspects, which might help to understand their possible histogenesis and biological behavior, will be reviewed...
Teratocarcinoma-derived growth factor-1 is upregulated in aldosterone-producing adenomas and increases aldosterone secretion and inhibits apoptosis in vitroTracy A Williams
Department of Medicine and Experimental Oncology, University of Torino, Torino, Italy
Hypertension 55:1468-75. 2010....
Intrathoracic splenosis: a case report and an update of invasive and noninvasive diagnostic techniquesEnrico Ruffini
Department of Thoracic Surgery, University of Torino, Torino, Italy
J Thorac Cardiovasc Surg 134:1594-5. 2007
Cytotoxic activity of the histone deacetylase inhibitor panobinostat (LBH589) in anaplastic thyroid cancer in vitro and in vivoMaria Graziella Catalano
Department of Clinical Pathophysiology, University of Turin, Torino, Italy
Int J Cancer 130:694-704. 2012....
Genetic relationship among atypical adenomatous hyperplasia, bronchioloalveolar carcinoma and adenocarcinoma of the lungLuca Morandi
Department of Oncology, Section of Anatomic Pathology M Malpighi, University of Bologna, Bellaria Hospital, Via Altura no 3, 40139 Bologna, Italy
Lung Cancer 56:35-42. 2007..Less frequently AAH foci could represent an early spread of cells from the main tumor, rather than a precursor lesion...
Localised pleural malignant mesothelioma. Report of two cases simulating pulmonary carcinoma and review of the literatureSofia Asioli
Section of Anatomic Pathology M. Malpighi Department of Oncologic Sciences, University of Bologna, Bellaria Hospital, Via Altura 3, 40139 Bologna, Italy
Virchows Arch 445:206-9. 2004..CONCLUSIONS: Localised malignant mesotheliomas are unusual and predominantly intrapulmonary growth is rare. Pathologists should be aware of this possibility to avoid misdiagnosis, particularly in small biopsies...
Crooke's hyalinization in silent corticotroph adenoma: report of two casesFederico Roncaroli
Department of Oncology, Service of Anatomic and Cytopathology, Institute of Anatomic and Cytopathology, Bellaria Hospital, Bologna, Italy
Endocr Pathol 13:245-9. 2002..This fact suggests that receptor overexpression or lack of receptor downregulation may result in hypersensitivity of neoplastic Crooke's cells to physiologic cortisol plasma levels...
Primary neuroendocrine (Merkel cell) carcinoma of the nippleSofia Asioli
Virchows Arch 440:443-4. 2002
