A Argiolas

Summary

Affiliation: University of Cagliari
Country: Italy

Publications

  1. ncbi request reprint Stimulation of dopamine receptors in the paraventricular nucleus of the hypothalamus of male rats induces penile erection and increases extra-cellular dopamine in the nucleus accumbens: Involvement of central oxytocin
    Salvatora Succu
    Bernard B Brodie Department of Neuroscience, Centre of Excellence for the Neurobiology of Addictions, University of Cagliari, S P Sestu Monserrato, Km 0 700, 09042 Monserrato, CA, Italy
    Neuropharmacology 52:1034-43. 2007
  2. doi request reprint Neuropeptides and central control of sexual behaviour from the past to the present: a review
    Antonio Argiolas
    Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy
    Prog Neurobiol 108:80-107. 2013
  3. ncbi request reprint Central control of penile erection: role of the paraventricular nucleus of the hypothalamus
    Antonio Argiolas
    Bernard B Brodie Department of Neuroscience, Centre of Excellence for the Neurobiology of Addictions, University of Cagliari, S P Sestu Monserrato Km 0 700, 09042 Monserrato, Cagliari, Italy
    Prog Neurobiol 76:1-21. 2005
  4. ncbi request reprint The neuropharmacology of yawning
    A Argiolas
    Bernard B Brodie Department of Neuroscience, University of Cagliari and Center for Neuropharmacology, National Research Council, Italy
    Eur J Pharmacol 343:1-16. 1998
  5. ncbi request reprint The role of oxytocin and the paraventricular nucleus in the sexual behaviour of male mammals
    Antonio Argiolas
    Bernard B Brodie Department of Neuroscience and Center of Excellence for The Neurobiology of Addictions, University of Cagliari, Cittadella Universitaria, S P Sestu Monserrato, Km 0 700, 09042 Monserrato, CA, Italy
    Physiol Behav 83:309-17. 2004
  6. ncbi request reprint The neurophysiology of the sexual cycle
    A Argiolas
    Bernard B Brodie Department of Neuroscience, Cittadella Universitaria, University of Cagliari, Sestu Monserrato, Italy
    J Endocrinol Invest 26:20-2. 2003
  7. ncbi request reprint ACTH- and alpha-MSH-induced grooming, stretching, yawning and penile erection in male rats: site of action in the brain and role of melanocortin receptors
    A Argiolas
    Bernard B Brodie Department of Neuroscience, Cagliari University, Cagliari, Italy
    Brain Res Bull 51:425-31. 2000
  8. ncbi request reprint Neuropeptides and sexual behaviour
    A Argiolas
    Bernard B Brodie Department of Neuroscience and Centre for Neuropharmacology, National Research Council, Cagliari, Italy
    Neurosci Biobehav Rev 23:1127-42. 1999
  9. ncbi request reprint The cannabinoid CB1 receptor antagonist SR 141716A induces penile erection by increasing extra-cellular glutamic acid in the paraventricular nucleus of male rats
    Salvatora Succu
    Bernard B Brodie Department of Neuroscience and Centre of Excellence for The Neurobiology of Addictions, University of Cagliari, S P Sestu Monserrato, Km 0 700, 09042 Monserrato, Italy
    Behav Brain Res 169:274-81. 2006
  10. ncbi request reprint Activation of gamma-aminobutyric acid(A) receptors in the paraventricular nucleus of the hypothalamus reduces apomorphine-, N-methyl-D-aspartic acid- and oxytocin-induced penile erection and yawning in male rats
    M Rosaria Melis
    Bernard B Brodie Department of Neuroscience, University of Cagliari, Via Porcell 4, 09124, Cagliari, Italy
    Neurosci Lett 281:127-30. 2000

Collaborators

  • M R Melis
  • Cristina Cocco
  • M P Castelli
  • G Diaz
  • Antonio Torsello
  • Alain Gueiffier
  • Salvatora Succu
  • Fabrizio Sanna
  • Tiziana Melis
  • Antonio Boi
  • Maria Stefania Mascia
  • Gian Luca Ferri
  • Roberta Possenti
  • Carla Brancia
  • Cecile Enguehard-Gueiffier
  • Michela Bagnasco
  • Filomena D'Amato
  • Barbara Noli
  • M Rosaria Melis
  • Ahmed El Hakmaoui
  • Peter Gmeiner
  • Harald Hubner
  • Hassan Allouchi
  • Andrea Levi
  • Romano Deghenghi
  • Daniela Cocchi
  • Giovanni Tulipano
  • Eugenio E Muller
  • S Succu
  • M S Spano

Detail Information

Publications38

  1. ncbi request reprint Stimulation of dopamine receptors in the paraventricular nucleus of the hypothalamus of male rats induces penile erection and increases extra-cellular dopamine in the nucleus accumbens: Involvement of central oxytocin
    Salvatora Succu
    Bernard B Brodie Department of Neuroscience, Centre of Excellence for the Neurobiology of Addictions, University of Cagliari, S P Sestu Monserrato, Km 0 700, 09042 Monserrato, CA, Italy
    Neuropharmacology 52:1034-43. 2007
    ..g., penile erection) with those controlling sexual motivation and sexual arousal...
  2. doi request reprint Neuropeptides and central control of sexual behaviour from the past to the present: a review
    Antonio Argiolas
    Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy
    Prog Neurobiol 108:80-107. 2013
    ..Such a decrease may be related to the discovery of orally effective, locally acting type V phosphodiesterase inhibitors for the therapy of erectile dysfunction. ..
  3. ncbi request reprint Central control of penile erection: role of the paraventricular nucleus of the hypothalamus
    Antonio Argiolas
    Bernard B Brodie Department of Neuroscience, Centre of Excellence for the Neurobiology of Addictions, University of Cagliari, S P Sestu Monserrato Km 0 700, 09042 Monserrato, Cagliari, Italy
    Prog Neurobiol 76:1-21. 2005
    ....
  4. ncbi request reprint The neuropharmacology of yawning
    A Argiolas
    Bernard B Brodie Department of Neuroscience, University of Cagliari and Center for Neuropharmacology, National Research Council, Italy
    Eur J Pharmacol 343:1-16. 1998
    ..In conclusion, in spite of some recent progress, little is known of, and more has to be done to identify, the neurochemical mechanisms underlying yawning at the central level...
  5. ncbi request reprint The role of oxytocin and the paraventricular nucleus in the sexual behaviour of male mammals
    Antonio Argiolas
    Bernard B Brodie Department of Neuroscience and Center of Excellence for The Neurobiology of Addictions, University of Cagliari, Cittadella Universitaria, S P Sestu Monserrato, Km 0 700, 09042 Monserrato, CA, Italy
    Physiol Behav 83:309-17. 2004
    ....
  6. ncbi request reprint The neurophysiology of the sexual cycle
    A Argiolas
    Bernard B Brodie Department of Neuroscience, Cittadella Universitaria, University of Cagliari, Sestu Monserrato, Italy
    J Endocrinol Invest 26:20-2. 2003
    ..Although the majority of results, which have clarified the mechanisms involved, have been performed in males, it is believed that similar mechanisms are also operative in females...
  7. ncbi request reprint ACTH- and alpha-MSH-induced grooming, stretching, yawning and penile erection in male rats: site of action in the brain and role of melanocortin receptors
    A Argiolas
    Bernard B Brodie Department of Neuroscience, Cagliari University, Cagliari, Italy
    Brain Res Bull 51:425-31. 2000
    ..The results show that ACTH(1-24) and alpha-MSH act in the hypothalamic periventricular region to induce the above responses and that grooming, stretching and yawning, but not penile erection, are mediated by melanocortin 4 receptors...
  8. ncbi request reprint Neuropeptides and sexual behaviour
    A Argiolas
    Bernard B Brodie Department of Neuroscience and Centre for Neuropharmacology, National Research Council, Cagliari, Italy
    Neurosci Biobehav Rev 23:1127-42. 1999
    ..Although still in the early stages, it is likely that these methodologies will provide new insights into the role of neuropeptides in the control of sexual behaviour...
  9. ncbi request reprint The cannabinoid CB1 receptor antagonist SR 141716A induces penile erection by increasing extra-cellular glutamic acid in the paraventricular nucleus of male rats
    Salvatora Succu
    Bernard B Brodie Department of Neuroscience and Centre of Excellence for The Neurobiology of Addictions, University of Cagliari, S P Sestu Monserrato, Km 0 700, 09042 Monserrato, Italy
    Behav Brain Res 169:274-81. 2006
    ..The present results show that SR 141716A induces penile erection by activating glutamic acid neurotransmission, which causes in turn the activation of paraventricular oxytocinergic neurons mediating penile erection...
  10. ncbi request reprint Activation of gamma-aminobutyric acid(A) receptors in the paraventricular nucleus of the hypothalamus reduces apomorphine-, N-methyl-D-aspartic acid- and oxytocin-induced penile erection and yawning in male rats
    M Rosaria Melis
    Bernard B Brodie Department of Neuroscience, University of Cagliari, Via Porcell 4, 09124, Cagliari, Italy
    Neurosci Lett 281:127-30. 2000
    ..The present results show that gamma-aminobutyric acid (GABA) inhibits penile erection and yawning by acting on GABA(A) receptors in the paraventricular nucleus of the hypothalamus...
  11. ncbi request reprint Pro-VGF-derived peptides induce penile erection in male rats: Involvement of paraventricular nitric oxide
    Salvatora Succu
    Bernard B Brodie Department of Neuroscience and Center of Excellence for the Neurobiology of Addiction, University of Cagliari, S P Monserrato Sestu, Km 0 700, 09042 Monserrato CA, Italy
    Neuropharmacology 49:1017-25. 2005
    ....
  12. ncbi request reprint The activation of gamma aminobutyric acid(A) receptors in the paraventricular nucleus of the hypothalamus reduces non-contact penile erections in male rats
    M R Melis
    Bernard B Brodie Department of Neuroscience, University of Cagliari, Cittadella Universitaria, SP Sestu Monserrato, 09042 Moserrato, CA, Italy
    Neurosci Lett 314:123-6. 2001
    ....
  13. ncbi request reprint Activation of GABAA and opioid receptors reduce penile erection induced by hexarelin peptides
    Salvatora Succu
    Bernard B Brodie Department of Neuroscience and Center of Excellence for The Neurobiology of Addictions, University of Cagliari, Cittadella Universitaria, S P Monserrato Sestu, Km 0 700, 09042 Monserrato CA, Italy
    Pharmacol Biochem Behav 76:563-70. 2003
    ....
  14. doi request reprint Oxytocin induces penile erection when injected into the ventral tegmental area of male rats: role of nitric oxide and cyclic GMP
    Salvatora Succu
    Bernard B Brodie Department of Neuroscience, University of Cagliari, 09042 Monserrato, Italy
    Eur J Neurosci 28:813-21. 2008
    ..NO in turn activates guanylate cyclase present in these neurons, thereby increasing cyclic GMP concentration...
  15. ncbi request reprint Effect of excitatory amino acid, dopamine, and oxytocin receptor antagonists on noncontact penile erections and paraventricular nitric oxide production in male rats
    M R Melis
    Bernard B Brodie Department of Neuroscience, University of Cagliari, Italy
    Behav Neurosci 114:849-57. 2000
    ..This may contribute to increased NO production in the PVN, and it may activate oxytocin neurons mediating this sexual response...
  16. ncbi request reprint Pro-VGF-derived peptides induce penile erection in male rats: possible involvement of oxytocin
    Salvatora Succu
    Bernard B Brodie Department of Neuroscience and Center of Excellence for the Neurobiology of Addiction, S P Monserrato Sestu, Km 0 700, 09042 Monserrato, University of Cagliari, Italy
    Eur J Neurosci 20:3035-40. 2004
    ....
  17. ncbi request reprint The oxytocin antagonist d(CH2)5Tyr(Me)2-Orn8-vasotocin reduces non-contact penile erections in male rats
    M R Melis
    Bernard B Brodie Department of Neuroscience, University of Cagliari, Italy
    Neurosci Lett 265:171-4. 1999
    ..The present results show that central oxytocin is involved in the expression of penile erection induced not only by drugs but also by sexual physiological stimuli...
  18. doi request reprint Phosphodiesterase type 5 inhibitors facilitate noncontact erections in male rats: site of action in the brain and mechanism of action
    Fabrizio Sanna
    Bernard B Brodie Department of Neuroscience, University of Cagliari, Monserrato, Cagliari 09042, Italy
    J Sex Med 6:2680-9. 2009
    ..Orally active phosphodiesterase type 5 inhibitors (PDE5i), used in the treatment of erectile dysfunction, facilitate the relaxation of cavernous smooth muscle tissues by reducing the degradation of cyclic guanosine monophosphate...
  19. ncbi request reprint Yawning: role of hypothalamic paraventricular nitric oxide
    M R Melis
    Bernard B Brodie Department of Neuroscience and Center for Neuropharmacology, National Research Council, University of Cagliari, Via Porcell 4, 09124 Cagliari, Italy
    Zhongguo Yao Li Xue Bao 20:778-88. 1999
    ....
  20. ncbi request reprint Cannabinoid CB1 receptors in the paraventricular nucleus and central control of penile erection: immunocytochemistry, autoradiography and behavioral studies
    M P Castelli
    Bernard B Brodie Department of Neuroscience, University of Cagliari, S P Sestu Monserrato, Km 0 700, 09042 Monserrato CA, Italy
    Neuroscience 147:197-206. 2007
    ..This increase is related to an enhanced pro-erectile effect of SR 141716A, which is still present 3 days after the end of the chronic treatment...
  21. ncbi request reprint EP 91073 prevents EP 80661-induced penile erection: new evidence for the existence of specific EP peptide receptors mediating penile erection
    M R Melis
    Bernard B. Brodie Department of Neuroscience, University of Cagliari, Via Porcell 4, 09124 Cagliari, Italy
    Neuropharmacology 41:254-62. 2001
    ....
  22. ncbi request reprint Central oxytocinergic neurotransmission: a drug target for the therapy of psychogenic erectile dysfunction
    M R Melis
    Bernard B Brodie Department of Neuroscience, University of Cagliari, S P Sestu Monserrato Km 0 700, 09042 Monserrato, Cagliari, Italy
    Curr Drug Targets 4:55-66. 2003
    ..These findings show that paraventricular oxytocinergic neurons projecting to extra-hypothalamic brain areas and to the spinal cord are a likely target for the treatment of erectile dysfunction of central origin...
  23. ncbi request reprint Morphine reduces penile erection induced by the cannabinoid receptor antagonist SR 141617A in male rats: role of paraventricular glutamic acid and nitric oxide
    Salvatora Succu
    Bernard B Brodie Department of Neuroscience and Centre of Excellence for The Neurobiology of Addictions, University of Cagliari, SP Monserrato Sestu, Italy
    Neurosci Lett 404:1-5. 2006
    ....
  24. doi request reprint Oxytocin injected into the ventral subiculum or the posteromedial cortical nucleus of the amygdala induces penile erection and increases extracellular dopamine levels in the nucleus accumbens of male rats
    Maria Rosaria Melis
    Bernard B Brodie Department of Neuroscience, University of Cagliari, Cittadella Universitaria, Monserrato, Cagliari, Italy
    Eur J Neurosci 30:1349-57. 2009
    ..g. penile erection and copulatory performance), but also its motivational/reward aspects, confirming a key role of oxytocin and dopamine in these processes...
  25. ncbi request reprint Oxytocin injected into the ventral tegmental area induces penile erection and increases extracellular dopamine in the nucleus accumbens and paraventricular nucleus of the hypothalamus of male rats
    Maria Rosaria Melis
    Bernard B Brodie Department of Neuroscience, University of Cagliari, S P Sestu Monserrato, Monserrato, Italy
    Eur J Neurosci 26:1026-35. 2007
    ....
  26. doi request reprint Oxytocin induces penile erection when injected into the ventral subiculum: role of nitric oxide and glutamic acid
    Maria Rosaria Melis
    Bernard B Brodie Department of Neuroscience, University of Cagliari, Cagliari Section, Cittadella Universitaria, SS 554, km 4 500, 09042 Monserrato, Cagliari, Italy
    Neuropharmacology 58:1153-60. 2010
    ..g., prefrontal cortex) modulating the activity of mesolimbic dopaminergic neurons...
  27. ncbi request reprint The cannabinoid antagonist SR 141716A (Rimonabant) reduces the increase of extra-cellular dopamine release in the rat nucleus accumbens induced by a novel high palatable food
    Tiziana Melis
    Bernard B Brodie Department of Neuroscience, University of Cagliari, 09042 Monserrato, Cagliari, Italy
    Neurosci Lett 419:231-5. 2007
    ....
  28. ncbi request reprint PIP3EA and PD-168077, two selective dopamine D4 receptor agonists, induce penile erection in male rats: site and mechanism of action in the brain
    Maria Rosaria Melis
    Bernard B Brodie Department of Neuroscience, Centre of Excellence for the Neurobiology of Addictions, University of Cagliari, Italy
    Eur J Neurosci 24:2021-30. 2006
    ....
  29. ncbi request reprint Antagonism of cannabinoid CB1 receptors in the paraventricular nucleus of male rats induces penile erection
    Maria Rosaria Melis
    Bernard B Brodie Department of Neuroscience and Center of Excellence for The Neurobiology of Addictions, University of Cagliari, S P Sestu Monserrato, Km 0 700, 09042 Monserrato, CA, Italy
    Neurosci Lett 359:17-20. 2004
    ..The present results show that cannabinoid CB1 receptors present in the paraventricular nucleus may influence erectile function and sexual activity by modulating paraventricular oxytocinergic neurons mediating erectile function...
  30. ncbi request reprint Reduction of drug-induced yawning and penile erection and of noncontact erections in male rats by the activation of GABAA receptors in the paraventricular nucleus: involvement of nitric oxide
    Maria Rosaria Melis
    Bernard B Brodie Department of Neuroscience, University of Cagliari, S P Monserrato Sestu, Km 0 700, 09042 Monserrato CA, Italy
    Eur J Neurosci 15:852-60. 2002
    ....
  31. ncbi request reprint The cannabinoid receptor antagonist SR-141716A induces penile erection in male rats: involvement of paraventricular glutamic acid and nitric oxide
    Maria Rosaria Melis
    Bernard B Brodie Department of Neuroscience and Centre of Excellence for The Neurobiology of Addictions, University of Cagliari, 09042 Monserrato, Italy
    Neuropharmacology 50:219-28. 2006
    ....
  32. ncbi request reprint Ghrelin injected into the paraventricular nucleus of the hypothalamus of male rats induces feeding but not penile erection
    Maria Rosario Melis
    Bernard B Brodie Department of Neuroscience, University of Cagliari, S P Sestu Monserrato, 09042 Monserrato, Italy
    Neurosci Lett 329:339-43. 2002
    ..The present results provide further support to the hypothesis that the GH secretagogue receptors mediating feeding are different from those mediating penile erection and activated by pro-erectile EP peptides...
  33. ncbi request reprint PD-168077, a selective dopamine D4 receptor agonist, induces penile erection when injected into the paraventricular nucleus of male rats
    Maria Rosaria Melis
    Bernard B Brodie Department of Neuroscience, Center of Excellence for the Neurobiology of Addictions, University of Cagliari, S P Sestu Monserrato, Km 0 700, 09042 Monserrato, Italy
    Neurosci Lett 379:59-62. 2005
    ..The present results show that D4 dopamine receptors present in the paraventricular nucleus may influence penile erection by modulating the activity of paraventricular oxytocinergic neurons mediating erectile function...
  34. ncbi request reprint Extra-cellular dopamine increases in the paraventricular nucleus of male rats during sexual activity
    Maria Rosaria Melis
    Bernard B Brodie Department of Neuroscience, University of Cagliari, S P Monserrato Sestu, Km 0 700, 09042 Monserrato CA, Italy
    Eur J Neurosci 17:1266-72. 2003
    ....
  35. ncbi request reprint Extracellular excitatory amino acids increase in the paraventricular nucleus of male rats during sexual activity: main role of N-methyl-d-aspartic acid receptors in erectile function
    Maria Rosaria Melis
    Bernard B Brodie Department of Neuroscience and Center of Excellence for The Neurobiology of Addictions, University of Cagliari, Cittadella Universitaria, S P Monserrato Sestu, Km 0 700, 09042 Monserrato CA, Italy
    Eur J Neurosci 19:2569-75. 2004
    ....
  36. doi request reprint Selective expression of TLQP-21 and other VGF peptides in gastric neuroendocrine cells and modulation by feeding
    Carla Brancia
    NEF Laboratory, Department of Cytomorphology, University of Cagliari, 09042 Monserrato Cagliari, Italy
    J Endocrinol 207:329-41. 2010
    ..The selective modulation of TLQP peptides suggests their involvement in peripheral neuro-endocrine mechanisms related to feeding responses and/or ECL cell regulation...
  37. ncbi request reprint Endogenous ghrelin is an orexigenic peptide acting in the arcuate nucleus in response to fasting
    Michela Bagnasco
    Department of Pharmacology, Chemotherapy and Medical Toxicology, University of Milan, Via Vanvitelli, 32 20129 Milan, Italy
    Regul Pept 111:161-7. 2003
    ....
  38. ncbi request reprint 2-[(4-phenylpiperazin-1-yl)methyl]imidazo(di)azines as selective D4-ligands. Induction of penile erection by 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine (PIP3EA), a potent and selective D4 partial agonist
    Cecile Enguehard-Gueiffier
    Laboratoire de Chimie Therapeutique, Faculte de Pharmacie, 31 Avenue Monge, F 37200 Tours, France
    J Med Chem 49:3938-47. 2006
    ..0 (46%) and 4.5 nM (57%), respectively. Our D4 agonist 3c induced penile erection in vivo when administered to rats. This effect was inhibited by L-745,870 a D4 selective antagonist, confirming the mechanistic pathway...