Luca Arcaini

Summary

Affiliation: University of Pavia
Country: Italy

Publications

  1. doi request reprint The BRAF V600E mutation in hairy cell leukemia and other mature B-cell neoplasms
    Luca Arcaini
    Departments of Hematology Oncology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo and University of Pavia, Pavia, Italy
    Blood 119:188-91. 2012
  2. pmc Outcome prediction of diffuse large B-cell lymphomas associated with hepatitis C virus infection: a study on behalf of the Fondazione Italiana Linfomi
    Michele Merli
    Haematologica 99:489-96. 2014
  3. pmc Prognostic assessment in patients with indolent B-cell lymphomas
    Luca Arcaini
    Division of Hematology, Department of Hematology and Oncology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, 27100 Pavia, Italy
    ScientificWorldJournal 2012:107892. 2012
  4. doi request reprint Immunochemotherapy with in vivo purging and autotransplant induces long clinical and molecular remission in advanced relapsed and refractory follicular lymphoma
    L Arcaini
    Division of Hematology, Fondazione IRCCS Policlinico S Matteo, University of Pavia, Pavia
    Ann Oncol 19:1331-5. 2008
  5. ncbi request reprint Correlation of the FLIPI score for follicular lymphoma with period of diagnosis and type of treatment
    Luca Arcaini
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Viale Golgi 19, 27100 Pavia, Italy
    Leuk Res 30:277-82. 2006
  6. doi request reprint Distinctive clinical and histological features of Waldenström's macroglobulinemia and splenic marginal zone lymphoma
    Luca Arcaini
    Division of Hematology, Department of Oncohematology, University of Pavia Medical School, Fondazione IRCCS Policlinico San Matteo, Italy
    Clin Lymphoma Myeloma Leuk 11:103-5. 2011
  7. doi request reprint Plerixafor and G-CSF for PBSC mobilization in patients with lymphoma who failed previous attempts with G-CSF and chemotherapy: a REL (Rete Ematologica Lombarda) experience
    Luca Arcaini
    Division of Hematology, Department of Oncohematology, University of Pavia Medical School, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Leuk Res 35:712-4. 2011
  8. ncbi request reprint Splenic marginal zone lymphoma: a prognostic model for clinical use
    Luca Arcaini
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, 27100 Pavia, Italy
    Blood 107:4643-9. 2006
  9. ncbi request reprint Nongastric marginal-zone B-cell MALT lymphoma: prognostic value of disease dissemination
    Luca Arcaini
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Viale Golgi 19, 27100 Pavia, Italy
    Oncologist 11:285-91. 2006
  10. ncbi request reprint Role of the molecular staging and response in the management of follicular lymphoma patients
    Luca Arcaini
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Italy
    Leuk Lymphoma 47:1018-22. 2006

Detail Information

Publications63

  1. doi request reprint The BRAF V600E mutation in hairy cell leukemia and other mature B-cell neoplasms
    Luca Arcaini
    Departments of Hematology Oncology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo and University of Pavia, Pavia, Italy
    Blood 119:188-91. 2012
    ..We conclude that the BRAF V600E mutation is present in all patients with HCL and that, in combination with clinical and morphologic features, represents a reliable molecular marker for this condition...
  2. pmc Outcome prediction of diffuse large B-cell lymphomas associated with hepatitis C virus infection: a study on behalf of the Fondazione Italiana Linfomi
    Michele Merli
    Haematologica 99:489-96. 2014
    ....
  3. pmc Prognostic assessment in patients with indolent B-cell lymphomas
    Luca Arcaini
    Division of Hematology, Department of Hematology and Oncology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, 27100 Pavia, Italy
    ScientificWorldJournal 2012:107892. 2012
    ..In this paper we summarized the current evidence regarding prognostic assessment of indolent follicular and non-follicular lymphomas...
  4. doi request reprint Immunochemotherapy with in vivo purging and autotransplant induces long clinical and molecular remission in advanced relapsed and refractory follicular lymphoma
    L Arcaini
    Division of Hematology, Fondazione IRCCS Policlinico S Matteo, University of Pavia, Pavia
    Ann Oncol 19:1331-5. 2008
    ..To evaluate the clinical outcome of patients with relapsed or refractory follicular lymphoma treated with immunochemotherapy, in vivo purging and high-dose therapy with autotransplant...
  5. ncbi request reprint Correlation of the FLIPI score for follicular lymphoma with period of diagnosis and type of treatment
    Luca Arcaini
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Viale Golgi 19, 27100 Pavia, Italy
    Leuk Res 30:277-82. 2006
    ..Aim of this study was to validate the FLIPI score in an independent series of follicular lymphoma patients and to correlate prognostic categories with the period of diagnosis and the use of anthracycline...
  6. doi request reprint Distinctive clinical and histological features of Waldenström's macroglobulinemia and splenic marginal zone lymphoma
    Luca Arcaini
    Division of Hematology, Department of Oncohematology, University of Pavia Medical School, Fondazione IRCCS Policlinico San Matteo, Italy
    Clin Lymphoma Myeloma Leuk 11:103-5. 2011
    ..In conclusion, despite similar outcomes of these 2 entities, SMZL appears as a disease with distinct clinical features and BM histology and a peculiar association with HCV infection...
  7. doi request reprint Plerixafor and G-CSF for PBSC mobilization in patients with lymphoma who failed previous attempts with G-CSF and chemotherapy: a REL (Rete Ematologica Lombarda) experience
    Luca Arcaini
    Division of Hematology, Department of Oncohematology, University of Pavia Medical School, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Leuk Res 35:712-4. 2011
    ..In conclusion, plerixafor combined with G-CSF allows a collection of adequate number of PBSC in approximately 40% of cases of poor mobilizer, heavily pre-treated pts with lymphoma, who need consolidation with ASCT...
  8. ncbi request reprint Splenic marginal zone lymphoma: a prognostic model for clinical use
    Luca Arcaini
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, 27100 Pavia, Italy
    Blood 107:4643-9. 2006
    ..In conclusion, with the use of readily available factors, this prognostic index may be an effective tool for evaluating the need for treatment and the intensity of therapy in an individual patient...
  9. ncbi request reprint Nongastric marginal-zone B-cell MALT lymphoma: prognostic value of disease dissemination
    Luca Arcaini
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Viale Golgi 19, 27100 Pavia, Italy
    Oncologist 11:285-91. 2006
    ..This study describes the clinical features and the natural history of nongastric marginal-zone lymphomas and highlights that the dissemination to lymph nodes and bone marrow is associated with a poorer outcome...
  10. ncbi request reprint Role of the molecular staging and response in the management of follicular lymphoma patients
    Luca Arcaini
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Italy
    Leuk Lymphoma 47:1018-22. 2006
    ..Absence of the bcl-2 rearrangement is related to a better EFS and the achievement of a molecular response in peripheral blood after therapy is associated with a better EFS...
  11. ncbi request reprint Prevalence of HCV infection in nongastric marginal zone B-cell lymphoma of MALT
    L Arcaini
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Italy
    Ann Oncol 18:346-50. 2007
    ....
  12. ncbi request reprint Primary nodal marginal zone B-cell lymphoma: clinical features and prognostic assessment of a rare disease
    Luca Arcaini
    Division of Haematology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
    Br J Haematol 136:301-4. 2007
    ..In univariate analysis worse OS was associated with: FLIPI (P = 0.02), age > 60 years (P = 0.05) and raised lactate dehydrogenase (P = 0.05). In multivariate analysis, only FLIPI predicted a worse OS (P = 0.02)...
  13. ncbi request reprint A model of in vivo purging with Rituximab and high-dose AraC in follicular and mantle cell lymphoma
    L Arcaini
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
    Bone Marrow Transplant 34:175-9. 2004
    ..Immunochemotherapy prior to mobilization produces B-cell depletion and seems to be a useful preparative step...
  14. ncbi request reprint Risk of second cancer in nongastric marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue: a population-based study from northern Italy
    Luca Arcaini
    Division of Hematology, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, University of Pavia, Pavia, Italy
    Clin Cancer Res 13:182-6. 2007
    ..The aim of this study was to define the risk of second cancer in nongastric marginal zone lymphomas of mucosa-associated lymphoid tissue (MALT)...
  15. ncbi request reprint Hepatitis C virus infection and antiviral treatment in marginal zone lymphomas
    Luca Arcaini
    Division of Hematology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Italy
    Curr Clin Pharmacol 5:74-81. 2010
    ....
  16. doi request reprint Impact of treatment-related liver toxicity on the outcome of HCV-positive non-Hodgkin's lymphomas
    Luca Arcaini
    Divison of Hematology, Fondazione IRCCS Policlinico S Matteo, University of Pavia, Viale Golgi 19, Pavia, Italy
    Am J Hematol 85:46-50. 2010
    ..This could be a limit to the application of immunochemotherapy programs. HCV+ lymphomas represent a distinct clinical subset of NHL that deserves specific clinical approach to limit liver toxicity and ameliorate survival...
  17. ncbi request reprint Splenic and nodal marginal zone lymphomas are indolent disorders at high hepatitis C virus seroprevalence with distinct presenting features but similar morphologic and phenotypic profiles
    Luca Arcaini
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Italy
    Cancer 100:107-15. 2004
    ..Splenic and nodal marginal zone lymphomas (MZL) are subtypes of marginal zone-derived neoplasms. Due to their rarity, little is known concerning their relation, pattern of dissemination, and treatment outcome...
  18. ncbi request reprint Combination of rituximab, cyclophosphamide, and vincristine induces complete hematologic remission of splenic marginal zone lymphoma
    Luca Arcaini
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Italy
    Clin Lymphoma 4:250-2. 2004
    ..The immunochemotherapy regimen was well tolerated and all patients exhibited complete remission. To our knowledge, this is the first report of splenic MZL showing response to a combination of rituximab with chemotherapy...
  19. doi request reprint Nodal marginal zone lymphoma: current knowledge and future directions of an heterogeneous disease
    Luca Arcaini
    Division of Hematology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Viale C Golgi 19, Pavia 27100, Italy
    Eur J Haematol 83:165-74. 2009
    ..We also summarize the clinical features and outcome of this rare lymphoma and we discuss the possible association with hepatitis C virus infection...
  20. doi request reprint Blast phase of essential thrombocythemia: A single center study
    Francesco Passamonti
    Division of Hematology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
    Am J Hematol 84:641-4. 2009
    ..JAK2 (V617F)-positive ET may evolve in few instances into JAK2-negative leukemia. The outcome of patients is poor whatever the treatment used...
  21. doi request reprint A dynamic prognostic model to predict survival in post-polycythemia vera myelofibrosis
    Francesco Passamonti
    Department of Hematology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, University of Pavia, Italy
    Blood 111:3383-7. 2008
    ..In conclusion, leukocytosis at diagnosis of PV is a risk factor for evolution in post-PV MF. A dynamic score based on hemoglobin level, and platelet and leukocyte count predicts survival at any time from diagnosis of post-PV MF...
  22. ncbi request reprint Bone marrow microvessel density in chronic myeloproliferative disorders: a study of 115 patients with clinicopathological and molecular correlations
    Emanuela Boveri
    Department of Surgical Pathology, University of Pavia Medical School, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Br J Haematol 140:162-8. 2008
    ..003), and anaemia (P < 0.001) independently correlated with MVD. In summary, this study indicates that assessment of BM angiogenesis, as measured by MVD, may be a useful additional tool in the histopathological definition of CMD...
  23. doi request reprint Prevalence and clinical significance of the MYD88 (L265P) somatic mutation in Waldenstrom's macroglobulinemia and related lymphoid neoplasms
    Marzia Varettoni
    Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Blood 121:2522-8. 2013
    ..In this latter condition, MYD88 (L265P) is associated with greater disease burden and higher risk of disease progression, and the mutation may therefore also represent a useful prognostic marker...
  24. doi request reprint Splenic marginal zone lymphoma: Clinical clustering of immunoglobulin heavy chain repertoires
    Luca Arcaini
    Division of Hematology, Fondazione IRCCS Policlinico San Matteo, University of Pavia Viale C Golgi 19, 27100 Pavia, Italy
    Blood Cells Mol Dis 42:286-91. 2009
    ....
  25. ncbi request reprint Long-term follow-up of young patients with essential thrombocythemia treated with pipobroman
    Francesco Passamonti
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Viale Golgi 19, Pavia, Italy
    Ann Hematol 83:495-7. 2004
  26. pmc Increased risk of lymphoid neoplasm in patients with myeloproliferative neoplasm: a study of 1,915 patients
    Elisa Rumi
    Division of Hematology, Department of Hematology Oncology, University of Pavia Medical School and Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Haematologica 96:454-8. 2011
    ..No difference in familial clustering was observed between the two groups...
  27. ncbi request reprint Immunochemotherapy with rituximab, vincristine and 5-day cyclophosphamide for heavily pretreated follicular lymphoma
    Mario Lazzarino
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
    Oncology 68:146-53. 2005
    ..Because of the different mechanisms of action and non-overlapping toxicities, combination of rituximab with chemotherapy is a rational approach...
  28. ncbi request reprint Clues to pathogenesis of Waldenström macroglobulinemia and immunoglobulin M monoclonal gammopathy of undetermined significance provided by analysis of immunoglobulin heavy chain gene rearrangement and clustering of B-cell receptors
    Marzia Varettoni
    Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Leuk Lymphoma 54:2485-9. 2013
    ..WM and IgM-MGUS-specific HCDR3 clusters do not occur with a frequency detectable with currently available databases, not supporting a B-cell receptor-driven pathogenesis in WM and IgM-MGUS...
  29. doi request reprint Assessment of bone marrow involvement in non-Hodgkin's lymphomas: comparison between histology and flow cytometry
    Michele Merli
    Department of Oncohematology, Fondazione IRCCS Policlinico S Matteo, University of Pavia, Italy
    Eur J Haematol 85:405-15. 2010
    ..In FL, diffuse large B-cell lymphoma (DLBCL) and LPL, FC underestimates the extent of infiltrate with respect to histology...
  30. doi request reprint Prognostic factors for thrombosis, myelofibrosis, and leukemia in essential thrombocythemia: a study of 605 patients
    Francesco Passamonti
    M D, Division of Hematology, University of Pavia, Fondazione IRCCS Policlinico San Matteo, Viale Golgi 19, 27100 Pavia, Italy
    Haematologica 93:1645-51. 2008
    ..Essential thrombocythemia is a chronic myeloproliferative disorder; patients with this disorder have a propensity to develop thrombosis, myelofibrosis, and leukemia...
  31. ncbi request reprint Long-term events in adult patients with clinical stage IA-IIA nonbulky Hodgkin's lymphoma treated with four cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine and adjuvant radiotherapy: a single-institution 15-year follow-up
    Ercole Brusamolino
    Clinica Ematologica and Servizio di Radioterapia Oncologica, Istituto di Ricovero e Cura a Carattere Scientifico, Policlinico San Matteo, University of Pavia, Pavia, Italy
    Clin Cancer Res 12:6487-93. 2006
    ..To report on long-term events after short doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) chemotherapy and adjuvant radiotherapy in favorable early-stage Hodgkin's lymphoma...
  32. ncbi request reprint Familial chronic myeloproliferative disorders: clinical phenotype and evidence of disease anticipation
    Elisa Rumi
    Department of Hematology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo Viale Golgi 49, 27100 Pavia, Italy
    J Clin Oncol 25:5630-5. 2007
    ..However, familial clustering is reported. The purpose of this study was to assess the prevalence and the clinical phenotype of familial CMDs, and to study the anticipation of disease onset in successive generations...
  33. ncbi request reprint JAK2 (V617F) as an acquired somatic mutation and a secondary genetic event associated with disease progression in familial myeloproliferative disorders
    Elisa Rumi
    Department of Hematology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo and University of Pavia School of Medicine, Pavia, Italy
    Cancer 107:2206-11. 2006
    ..The authors studied the biologic significance of the JAK2 (V617F) mutation in familial myeloproliferative disorders...
  34. pmc Red blood cell transfusion-dependency implies a poor survival in primary myelofibrosis irrespective of IPSS and DIPSS
    Chiara Elena
    Department of Hematology Oncology, Division of Hematology, University of Pavia Medical School and Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
    Haematologica 96:167-70. 2011
    ..This study suggests that red blood cell transfusion-dependency should be considered to improve risk stratification of primary myelofibrosis during follow up...
  35. ncbi request reprint High-resolution genome-wide array comparative genomic hybridization in splenic marginal zone B-cell lymphoma
    Francesca Novara
    Department of Human end Hereditary Pathology, Section of Medical Genetics, University of Pavia, Pavia 27100, Italy
    Hum Pathol 40:1628-37. 2009
    ..01) and del(17p) (P = .02). Hepatitis C virus-positive splenic marginal zone B-cell lymphoma patients have no specific chromosome alterations. Patients with poor prognosis are characterized by distinctive imbalances...
  36. ncbi request reprint Associated cancers in Waldenström macroglobulinemia: clues for common genetic predisposition
    Enrica Morra
    Division of Hematology, Niguarda Ca Granda Hospital, Milano, Italy
    Clin Lymphoma Myeloma Leuk 13:700-3. 2013
    ..The cause of second cancers in LPDs is probably multifactorial, and the relative contribution of treatments, genetic predisposition, and immune dysfunction typical of LPDs is still unclear...
  37. ncbi request reprint Relation between JAK2 (V617F) mutation status, granulocyte activation, and constitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders
    Francesco Passamonti
    Department of Hematology, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Blood 107:3676-82. 2006
    ..This exemplifies a novel paradigm in which a somatic gain-of-function mutation is initially responsible for clonal expansion of hematopoietic cells and later for their abnormal trafficking via an activated cell progeny...
  38. ncbi request reprint Polycythemia vera in young patients: a study on the long-term risk of thrombosis, myelofibrosis and leukemia
    Francesco Passamonti
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Italy
    Haematologica 88:13-8. 2003
    ..The aim of this study was to define the long-term risk of thrombosis, acute leukemia (AL) and myelofibrosis with myeloid metaplasia (MMM) in young PV patients...
  39. ncbi request reprint An insidious presentation of splenic marginal zone lymphoma
    Sara Burcheri
    Division of Hematology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Viale Golgi 19, 27100 Pavia, Italy
    Clin Lymphoma Myeloma 7:432-3. 2007
    ..After the splenectomy, the blood cell count normalized, and neither BM nor peripheral blood involvement appeared after 12 months of follow-up...
  40. ncbi request reprint Life expectancy and prognostic factors for survival in patients with polycythemia vera and essential thrombocythemia
    Francesco Passamonti
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
    Am J Med 117:755-61. 2004
    ..To assess life expectancy and prognostic factors for survival in patients with polycythemia vera and essential thrombocythemia...
  41. ncbi request reprint Increased risk of pregnancy complications in patients with essential thrombocythemia carrying the JAK2 (617V>F) mutation
    Francesco Passamonti
    Department of Hematology, University of Pavia Medical School, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Policlinico San Matteo, Pavia, Italy
    Blood 110:485-9. 2007
    ..A relationship was found between JAK2 (617V>F) and fetal loss (P = .05). This study indicates that patients carrying the JAK2 (617V>F) mutation have higher risk of developing pregnancy complications...
  42. ncbi request reprint A paraumbilical lymphomatous mass
    Sara Burcheri
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
    Eur J Haematol 77:180. 2006
  43. doi request reprint Twenty-one cases of blastic plasmacytoid dendritic cell neoplasm: focus on biallelic locus 9p21.3 deletion
    Marco Lucioni
    University of Pavia Medical School, Istituti di Ricovero e Cura a Carattere Scientifico, San Matteo, Italy
    Blood 118:4591-4. 2011
    ....
  44. ncbi request reprint Clinical activity of everolimus in relapsed/refractory marginal zone B-cell lymphomas: results of a phase II study of the International Extranodal Lymphoma Study Group
    Annarita Conconi
    Division of Haematology, Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, AOU Maggiore della Carita, Novara, Italy Haematology Unit, Department of Internal Medicine, Ospedale degli Infermi, Biella, Italy
    Br J Haematol 166:69-76. 2014
    ..Lower doses of the drug and, perhaps, different strategies including combination with additional agents need to be explored...
  45. doi request reprint Alteration of BIRC3 and multiple other NF-κB pathway genes in splenic marginal zone lymphoma
    Davide Rossi
    Division of Hematology, Department of Clinical and Experimental Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy
    Blood 118:4930-4. 2011
    ..Genetic lesions of NF-κB provide a molecular basis for the pathogenesis of more than 30% of SMZLs and offer a suitable target for NF-κB therapeutic approaches in this lymphoma...
  46. pmc Indolent B-cell lymphomas associated with HCV infection: clinical and virological features and role of antiviral therapy
    Luca Arcaini
    Department of Hematology Oncology, University of Pavia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Clin Dev Immunol 2012:638185. 2012
    ....
  47. ncbi request reprint Leukemic transformation of polycythemia vera: a single center study of 23 patients
    Francesco Passamonti
    Division of Hematology, IRCCS San Matteo Polyclinic, University of Pavia, Pavia, Italy
    Cancer 104:1032-6. 2005
    ..Acute leukemia (AL) may occur as rare and late event of polycythemia vera (PV)...
  48. ncbi request reprint Pharmacokinetic behavior of rituximab: a study of different schedules of administration for heterogeneous clinical settings
    Mario B Regazzi
    Department of Pharmacology, Clinical Medicine IRCCS Policlinico San Matteo, Pavia, Italy
    Ther Drug Monit 27:785-92. 2005
    ..Because several studies reported an association between response and serum Rituximab concentrations, a treatment based on a pharmacokinetic model may be useful for predicting the desired drug concentration...
  49. doi request reprint CD5(-) diffuse large B-cell lymphoma with peculiar cyclin D1+ phenotype. Pathologic and molecular characterization of a single case
    Marco Lucioni
    Anatomic Pathology, Foundation IRCCS Policlinico San Matteo and University of Pavia, 27100 Pavia, Italy
    Hum Pathol 42:1204-8. 2011
    ..Search for t(11;14) with fluorescence in situ hybridization probes should always be performed in doubtful cases...
  50. ncbi request reprint A combination of dexamethasone, cyclophosphamide, etoposide, and cisplatin is less toxic and more effective than high-dose cyclophosphamide for peripheral stem cell mobilization in multiple myeloma
    Alessandro Corso
    Division of Hematology, Istituto scientifico San Matteo, University of Pavia, Italy
    Haematologica 87:1041-5. 2002
    ..The purpose of this study was to compare the efficacy and toxicity of two regimens for peripheral blood stem cell (PBSC) mobilization in multiple myeloma (MM) patients...
  51. ncbi request reprint Prognostic factors and life expectancy in myelodysplastic syndromes classified according to WHO criteria: a basis for clinical decision making
    Luca Malcovati
    Division of Hematology, IRCCS, Policlinico San Matteo, 27100 Pavia, Italy
    J Clin Oncol 23:7594-603. 2005
    ....
  52. pmc Stereotyped patterns of B-cell receptor in splenic marginal zone lymphoma
    Silvia Zibellini
    Division of Hematology, Department of Oncohematology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Viale Golgi 19, Pavia, Italy
    Haematologica 95:1792-6. 2010
    ..Overall, data suggest that the pathogenesis of splenic marginal zone lymphoma may involve also HCV-unrelated epitopes or an antigenic trigger common to other indolent lymphomas...
  53. ncbi request reprint Marginal zone-related neoplasms of splenic and nodal origin
    Luca Arcaini
    Division of Hematology, IRCCS Policlinico San Matteo, University of Pavia, Italy
    Haematologica 88:80-93. 2003
    ..Treatment options are heterogeneous, including a watch-and-wait policy, surgery with or without chemotherapy, purine analogs, and interferon. No prospective studies have been conducted so far...
  54. ncbi request reprint B-cell posttransplant lymphoproliferative disorders in heart and/or lungs recipients: clinical and molecular-histogenetic study of 17 cases from a single institution
    Marco Lucioni
    Anatomic Pathology Section, Department of Human Pathology, University of Pavia, IRCCS Policlinico San Matteo, Pavia, Italy
    Transplantation 82:1013-23. 2006
    ..This study details the clinicopathological and molecular features of 17 B-cell PTLDs observed in a single center series of 988 heart and/or lung transplant recipients...
  55. doi request reprint The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation
    Davide Rossi
    Division of Hematology, Department of Clinical and Experimental Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy
    Blood 117:3391-401. 2011
    ..0%; P = .009). The molecular dissection of RS into biologically distinct categories highlights the genetic heterogeneity of this disorder and provides clinically relevant information for refining the prognostic stratification of patients...
  56. pmc Novel agents in indolent lymphomas
    Michele Merli
    Division of Hematology, Department of Internal Medicine, Ospedale di Circolo and Fondazione Macchi, University of Insubria, Varese, Italy
    Ther Adv Hematol 4:133-48. 2013
    ..The development of these new drugs may change in the near future the approach to iNHL patients, leading to better tolerated and effective therapy regimens...
  57. ncbi request reprint Reduced hypoxic ventilatory response with preserved blood oxygenation in yoga trainees and Himalayan Buddhist monks at altitude: evidence of a different adaptive strategy?
    Luciano Bernardi
    Department of Internal Medicine, University of Pavia and IRCCS Ospedale S Matteo, Pavia, Italy
    Eur J Appl Physiol 99:511-8. 2007
    ..Respiratory adaptations induced by the practice of yoga may represent an efficient strategy to cope with altitude-induced hypoxia...
  58. ncbi request reprint Monitoring of minimal residual disease after CHOP and rituximab in previously untreated patients with follicular lymphoma
    Alessandro Rambaldi
    Divisione di Ematologia, Ospedali Riuniti Bergamo, Largo Barozzi 1, 24100 Bergamo, Italy
    Blood 99:856-62. 2002
    ..001)...
  59. ncbi request reprint Quantitative PCR of bone marrow BCL2/IgH+ cells at diagnosis predicts treatment response and long-term outcome in follicular non-Hodgkin lymphoma
    Alessandro Rambaldi
    Divisione di Ematologia, Ospedali Riuniti Largo Barozzi 1, 24100, Bergamo, Italy
    Blood 105:3428-33. 2005
    ..006). RQ-PCR performed at presentation on BM samples predicts treatment response and long-term clinical outcome in patients with follicular lymphoma...
  60. ncbi request reprint Most cases of primary salivary mucosa-associated lymphoid tissue lymphoma are associated either with Sjoegren syndrome or hepatitis C virus infection
    Achille Ambrosetti
    Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy
    Br J Haematol 126:43-9. 2004
    ..The close association of SGML with either autoimmune diseases or HCV infection in our series (73%) confirms their possible role in the pathogenesis of these lymphomas...
  61. ncbi request reprint Role of anti-hepatitis C virus (HCV) treatment in HCV-related, low-grade, B-cell, non-Hodgkin's lymphoma: a multicenter Italian experience
    Daniele Vallisa
    Department of Oncology and Hematology, G da Saliceto Hospital, Piacenza, Via Taverna 49, 29100 Piacenza, Italy
    J Clin Oncol 23:468-73. 2005
    ..The biologic mechanisms underlying the lymphomagenic activity of the virus so far are under investigation. In this study, the role of antiviral (anti-HCV) treatment in B-NHL associated with HCV infection is evaluated...
  62. ncbi request reprint Management of primary mediastinal B-cell lymphoma with sclerosis: advances and caveats
    Luca Arcaini
    Haematologica 87:1238-9. 2002
  63. ncbi request reprint HLA typing and VH gene rearrangement analysis in a family with hairy cell leukaemia
    Elisa Rumi
    Leuk Lymphoma 48:805-7. 2007