Pietro Apostoli

Summary

Affiliation: University of Brescia
Country: Italy

Publications

  1. ncbi request reprint [Significance of biological indicators of mercury exposure]
    P Apostoli
    Cattedra di Igiene Industriale, Universita degli Studi di Brescia, p le Spedali Civili 1, 25123 Brescia
    Med Lav 94:231-41. 2003
  2. ncbi request reprint [The Italian version of "OREGE" (Outil de Repérage et d'Evaluation des Gestes) of the INRS (Institut national de recherche et de sécurité) for the assessment of musculoskeletal disorders of the upper limb]
    P Apostoli
    Cattedra di Igiene Industriale, Universita degli Studi di Brescia
    G Ital Med Lav Ergon 24:3-25. 2002
  3. ncbi request reprint [Evidence of work-related musculo-skeletal disorders of the upper extremities and current methods of risk assessment: can Charlie Chaplin give us any suggestions in "modern times"]
    P Apostoli
    Dipartimento di Medicina Sperimentale ed Applicata, Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    Med Lav 100:384-95. 2009
  4. pmc Evolutionary age of repetitive element subfamilies and sensitivity of DNA methylation to airborne pollutants
    Hyang Min Byun
    Laboratory of Environmental Epigenetics, Exposure Epidemiology and Risk Program, Harvard School of Public Health, Boston, MA, USA
    Part Fibre Toxicol 10:28. 2013
  5. pmc Effects of airborne pollutants on mitochondrial DNA methylation
    Hyang Min Byun
    Laboratory of Environmental Epigenetics, Exposure Epidemiology and Risk Program, Harvard School of Public Health, Boston, MA 02115, USA
    Part Fibre Toxicol 10:18. 2013
  6. pmc Ambient PM exposure and DNA methylation in tumor suppressor genes: a cross-sectional study
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N, Lakeshore Drive, Chicago, 60611, USA
    Part Fibre Toxicol 8:25. 2011
  7. pmc Airborne particulate matter and mitochondrial damage: a cross-sectional study
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Environ Health 9:48. 2010
  8. ncbi request reprint Relationship between PCBs in blood and D-glucaric acid in urine
    P Apostoli
    Chair of Industrial Hygiene, Department of Experimental and Applied Medicine, University of Brescia, P le Spedali Civili, 1, Brescia 25123, Italy
    Toxicol Lett 144:17-26. 2003
  9. ncbi request reprint [Efficacy and appropriateness in updating and validating the activities of the occupational health physician]
    P Apostoli
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia
    Med Lav 100:308-12. 2009
  10. ncbi request reprint [Polychlorinated dibenzofurans and cancer]
    Pietro Apostoli
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 33:185-92. 2011

Detail Information

Publications111 found, 100 shown here

  1. ncbi request reprint [Significance of biological indicators of mercury exposure]
    P Apostoli
    Cattedra di Igiene Industriale, Universita degli Studi di Brescia, p le Spedali Civili 1, 25123 Brescia
    Med Lav 94:231-41. 2003
    ..It was considered appropriate to update of the significance and use of the different mercury exposure indicators...
  2. ncbi request reprint [The Italian version of "OREGE" (Outil de Repérage et d'Evaluation des Gestes) of the INRS (Institut national de recherche et de sécurité) for the assessment of musculoskeletal disorders of the upper limb]
    P Apostoli
    Cattedra di Igiene Industriale, Universita degli Studi di Brescia
    G Ital Med Lav Ergon 24:3-25. 2002
    ..The expected results are: a critical review of the method, a comparison with the other most known evaluation methods and the selection of the best method for specific work activity...
  3. ncbi request reprint [Evidence of work-related musculo-skeletal disorders of the upper extremities and current methods of risk assessment: can Charlie Chaplin give us any suggestions in "modern times"]
    P Apostoli
    Dipartimento di Medicina Sperimentale ed Applicata, Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    Med Lav 100:384-95. 2009
    ....
  4. pmc Evolutionary age of repetitive element subfamilies and sensitivity of DNA methylation to airborne pollutants
    Hyang Min Byun
    Laboratory of Environmental Epigenetics, Exposure Epidemiology and Risk Program, Harvard School of Public Health, Boston, MA, USA
    Part Fibre Toxicol 10:28. 2013
    ..The purpose of the study is to evaluate sensitivity of DNA methylation in differentially‒evolved LINE, Alu, and HERV subfamilies to different types of airborne pollutants...
  5. pmc Effects of airborne pollutants on mitochondrial DNA methylation
    Hyang Min Byun
    Laboratory of Environmental Epigenetics, Exposure Epidemiology and Risk Program, Harvard School of Public Health, Boston, MA 02115, USA
    Part Fibre Toxicol 10:18. 2013
    ..However, no study has yet investigated whether mitochondrial DNA methylation is sensitive to pro-oxidant environmental exposures...
  6. pmc Ambient PM exposure and DNA methylation in tumor suppressor genes: a cross-sectional study
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N, Lakeshore Drive, Chicago, 60611, USA
    Part Fibre Toxicol 8:25. 2011
    ....
  7. pmc Airborne particulate matter and mitochondrial damage: a cross-sectional study
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Environ Health 9:48. 2010
    ..Although mitochondria are both the major intracellular source and target of oxidative stress, the effect of PM on mitochondria has never been evaluated in exposed individuals...
  8. ncbi request reprint Relationship between PCBs in blood and D-glucaric acid in urine
    P Apostoli
    Chair of Industrial Hygiene, Department of Experimental and Applied Medicine, University of Brescia, P le Spedali Civili, 1, Brescia 25123, Italy
    Toxicol Lett 144:17-26. 2003
    ....
  9. ncbi request reprint [Efficacy and appropriateness in updating and validating the activities of the occupational health physician]
    P Apostoli
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia
    Med Lav 100:308-12. 2009
    ..from the point of view of efficacy and appropriateness...
  10. ncbi request reprint [Polychlorinated dibenzofurans and cancer]
    Pietro Apostoli
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 33:185-92. 2011
    ..The PCDF as a group may be therefore classified at limited evidence of carcinogenicity. This paper concludes the cycle of review about other POPs, i.e. dioxins and PCBs...
  11. ncbi request reprint [Mechanisms of action for metallic elements and their species classified as R40 by EU]
    P Apostoli
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 31:54-60. 2009
    ....
  12. ncbi request reprint [Mechanisms of action for metallic elements and their species classified carcinogen R 45 and R 49 by EU]
    P Apostoli
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 30:382-91. 2008
    ..It has been also strongly supported the hypothesis that the metallic elements may act as a co-carcinogen with other organic compounds, for example with PAH...
  13. ncbi request reprint [Instruments for updating the occupational physician activities]
    P Apostoli
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 30:254-7. 2008
    ..Some aspects related to definitions, significance, production of guide lines, consensus conference reports, good practices statements are presented and discussed...
  14. ncbi request reprint [Carcinogenicity of metallic elements: general considerations about their identification and monitoring and about their main mechanisms of action. Part 1: general aspects]
    P Apostoli
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 30:186-91. 2008
    ....
  15. ncbi request reprint [Quality assurance to efficacy-effectiveness measuring in occupational medicine]
    P Apostoli
    Dipartimento di Medicina Sperimentale ed Applicatta, Lavoro Università degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 28:131-4. 2006
    ..To these aims has been addressed the meeting held in Bergamo and organized by the Lombard section of SIMLII in December 2005 whose main contributions are published in this GIMLE special issue...
  16. ncbi request reprint [Lead and blood pressure]
    P Apostoli
    Dipartimento di Medicina Sperimentale ed Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 27:22-32. 2005
    ..It presents itself in a large range of doses, it is quantitatively very modest, it appears more evident at low doses, thus we could hypothesize different mechanisms for different doses...
  17. ncbi request reprint [Report on the activities carried out in the research project of the Ministry of Instruction, University, and Research entitled "Environmental and occupational exposure to inorganic lead: assessment of toxic effects of current doses and related preventive
    P Apostoli
    Dipartimento di Medicina Sperimentale ed Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 27:6-14. 2005
    ..The results of the research, presented in detail in the current issue, do confirm the inadequacy of the biological exposure index nowadays ruled by Lex 25/2002...
  18. ncbi request reprint Influence of genetic polymorphisms of CYP1A1 and GSTM1 on the urinary levels of 1-hydroxypyrene
    P Apostoli
    Chair of Industrial Hygiene, Department of Experimental and Applied Medicine, University of Brescia, P le Spedali Civili, 1, Brescia 25123, Italy
    Toxicol Lett 144:27-34. 2003
    ..No influence of the genetic polymorphism of CYP1A1 and GSTM1 on the urinary levels of 1-OH-P was observed in this study...
  19. ncbi request reprint [Metallic elements in 31st updating of 67/548/EEC directive]
    P Apostoli
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Brescia, Italy
    G Ital Med Lav Ergon 31:177-81. 2009
    ....
  20. ncbi request reprint [Lead and cardiopathy]
    P Apostoli
    Cattedra di Igiene Industriale, Universita degli Studi di Brescia, p le Spedali Civili 1, 25123 Brescia
    Med Lav 95:124-32. 2004
    ..The studies dealing with the relationship between cardiovascular disease and exposure to environmental and occupational chemical risks are out-dated and insufficient. However, this is not true of studies on lead...
  21. ncbi request reprint Metal ions affecting reproduction and development
    Pietro Apostoli
    Department of Experimental and Applied Medicine, Unit of Occupational Medicine and Industrial Hygiene, University of Brescia, P le Spedali Civili, 1, I 25123 Brescia, Italy
    Met Ions Life Sci 8:263-303. 2011
    ..Also, for females the evidences of specific aspects such as fertility or abortions are usually higher and clearer from animal experiments than from human studies...
  22. ncbi request reprint [Classification as carcinogenic for 2,3,7,8-tetrachlorodibenzo-para-dioxin: an eventful journey]
    Pietro Apostoli
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 33:84-99. 2011
    ..In this paper a literature review accompanied by comments is reported with the aim to provide information about the evaluation process and tools for its more critical and scrupulous interpretation...
  23. ncbi request reprint [Polychloro biphenils (PCBS) and cancer]
    P Apostoli
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia
    G Ital Med Lav Ergon 31:419-27. 2009
    ..Critics are the identification of the congeners more diffused and persistent and therefore more representative and the correlation with early effects or specific metabolic alterations...
  24. doi request reprint Persistent organochlorine compounds in fetal and maternal tissues: evaluation of their potential influence on several indicators of fetal growth and health
    Roberto Bergonzi
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Sci Total Environ 409:2888-93. 2011
    ..Mothers of neonates born by preterm programmed caesarean delivery showed significantly (p<0.005 for both) higher serum p,p'-DDE serum concentrations and p,p'-DDT levels in the adipose tissue, as compared to mothers delivering at term...
  25. doi request reprint Stress proteins and oxidative damage in a renal derived cell line exposed to inorganic mercury and lead
    Alessandra Stacchiotti
    Human Anatomy Unit, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Italy
    Toxicology 264:215-24. 2009
    ..Indeed, different chaperones are involved in the specific nephrotoxic mechanism of these environmental pollutants and work together for cell survival...
  26. doi request reprint Polychlorinated biphenyls in serum, liver and adipose tissue of subjects with hepatocellular carcinoma living in a highly polluted area
    Claudia Zani
    Institute of Hygiene, Epidemiology and Public Health, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Chemosphere 91:194-9. 2013
    ..This study confirms that serum lipid-adjusted PCBs concentration is a valid measure of PCBs body storage and is highly correlated with PCBs concentration detected in other biological samples...
  27. doi request reprint Lack of correlation between blood lead and serum prolactin levels among lead exposed workers
    Simona Catalani
    Department of Experimental and Applied Medicine, Section of Industrial Hygiene, University of Brescia, Brescia, Italy
    Biomarkers 17:513-9. 2012
    ..The results do not support a routine use of S-PRL as a biomarker of effect in lead exposed workers...
  28. ncbi request reprint [Study of possible urban environmental pollution by a steel plant through the biological monitoring of urine and hair in children]
    Valter Carraro
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia
    G Ital Med Lav Ergon 34:141-50. 2012
    ..As a whole our survey demonstrated that there is no exposure to metallic elements representing a significant risk for this particular groups of general population possibly exposed to environmental pollution...
  29. ncbi request reprint [Introduction: scope and purpose of the multicenter project " Assessment of effects due to low doses in inorganic mercury following environmental and occupational exposure: human and in vitro studies on specific toxicity mechanisms"]
    L Alessio
    Cattedra di Medicina del Lavoro, Universita degli Studi di Brescia, p le Spedali Civili 1, 25123 Brescia
    Med Lav 93:148-56. 2002
    ..The results of this research project are described and discussed in the following papers...
  30. doi request reprint Biomarkers of exposure to aromatic hydrocarbons and methyl tert-butyl ether in petrol station workers
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, Occupational Medicine and Industrial Hygiene, University of Brescia, Italy
    Biomarkers 17:343-51. 2012
    ..Linear regression confirmed that occupational exposure was a main predictor of U-MTBE, U-B and S-PMA values, both the latter confounded by smoking habits. The study supports the usefulness of biomonitoring even at low exposure levels...
  31. ncbi request reprint [Evaluation of the dose of mercury in exposed and control subjects]
    P Apostoli
    Cattedra di Medicina del Lavoro e Cattedra di Igiene Industriale, Universita degli Studi di Brescia, p le Spedali Civili 1, 25123 Brescia
    Med Lav 93:159-75. 2002
    ..The aim of this paper was to analyse the concentrations of HgU and HgB in three different groups: 122 workers exposed, 18 workers formerly exposed and 196 subjects not occupationally or environmentally exposed to mercury...
  32. ncbi request reprint [Biomarkers of effect and susceptibility to low doses of benzene]
    Giuseppe De Palma
    Dipartimento di Specialità Medico Chirurgiche, Scienze Radiologiche e Sanità Pubblica, Sezione Sanità Pubblica e Scienze Umane, Universita degli Studi di Brescia, Brescia, Italy
    G Ital Med Lav Ergon 35:259-62. 2013
    ....
  33. ncbi request reprint Focal adhesion molecules as potential target of lead toxicity in NRK-52E cell line
    Roberta Giuliani
    Unit of Biochemistry, School of Medicine, University of Brescia, Italy
    FEBS Lett 579:6251-8. 2005
    ..These effects appeared to be strictly associated to the Pb-induced arrest of cell cycle at G0/G1 phase also proved in this cell line...
  34. doi request reprint Polychlorinated biphenyls and thyroid hormone serum concentrations among people living in a highly polluted area: a cross-sectional population-based study
    Francesco Donato
    Department of Experimental and Applied Medicine, Institute of Hygiene, Epidemiology and Public Health, University of Brescia, Viale Europa 11, Brescia, Italy
    Environ Res 108:380-6. 2008
    ..Polychlorinated biphenyls (PCBs) may interact with several thyroid functions. Severe environmental pollution by PCBs has been observed in Brescia, Italy, due to the presence of a factory that produced these compounds until 1984...
  35. doi request reprint Cobalt triggers necrotic cell death and atrophy in skeletal C2C12 myotubes
    Francesca Rovetta
    Unit of Biotechnologies, Department of Molecular and Translational Medicine, University of Brescia, Brescia I 25123, Italy Interuniversity Institute of Myology IIM, Italy
    Toxicol Appl Pharmacol 271:196-205. 2013
    ..Overall, these results suggested that cobalt may impact skeletal muscle homeostasis as an inducer of cell necrosis and myofiber atrophy. ..
  36. doi request reprint Evaluation of different methods to determine total serum lipids for normalization of circulating organochlorine compounds
    Roberto Bergonzi
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Brescia, Italy
    Int Arch Occup Environ Health 82:1241-7. 2009
    ..The study was aimed at: (i) evaluating the validity of these formulae; (ii) evaluating the influence of different estimates on serum levels of lipid adjusted persistent organochlorine compounds...
  37. ncbi request reprint Target-specific action of organochlorine compounds in reproductive and nonreproductive tissues of estrogen-reporter male mice
    R Villa
    3rd Laboratory Biotechnology, Civic Hospital of Brescia, 25123 Brescia, Italy
    Toxicol Appl Pharmacol 201:137-48. 2004
    ..We conclude that these organochlorines modulate differently the expression of estrogen-regulated genes in male mice. Their effect is tissue- and compound-specific and is dependent on the energetic balance...
  38. ncbi request reprint [Skin, its appendages and secretions as matrixes for biological monitoring of toxic elements]
    P Apostoli
    Medicina del Lavoro e Igiene Industriale, Dipartimento di Medicina Sperimentale ed Applicata, Universita degli Studi di Brescia
    G Ital Med Lav Ergon 24:188-91. 2002
  39. ncbi request reprint Synthesis of the results of studies performed on subjects exposed to low doses of mercury
    L Alessio
    Cattedra di Medicina del Lavoro, Universita degli Studi di Brescia, p le Spedali Civili 1, 25123 Brescia
    Med Lav 93:259-64. 2002
  40. doi request reprint Biological monitoring of tungsten (and cobalt) in workers of a hard metal alloy industry
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, University of Brescia, Italy
    Int Arch Occup Environ Health 83:173-81. 2010
    ..To evaluate a combined biomonitoring approach based on both cobalt and tungsten determination in workers of the hard metal alloy sector...
  41. ncbi request reprint Exposure to polychlorinated biphenyls in residents near a chemical factory in Italy: the food chain as main source of contamination
    Francesco Donato
    Institute of Hygiene, Epidemiology and Public Health, Universita di Brescia, Facolta di Medicina e Chirurgia, Viale Europa 11, 25123 Brescia, Italy
    Chemosphere 64:1562-72. 2006
    ..In conclusion, we found high serum PCB levels in humans living in a highly polluted area in an industrialized town in Italy, due mainly to consumption of food produced in polluted areas...
  42. ncbi request reprint [Usque tandem? Reflections on Legislative Decree of February 2, 2002, No.25]
    P Apostoli
    Cattedra di Igiene Industriale, Dipartimento di Medicina Sperimentale ed Applicata, Universita degli Studi di Brescia
    G Ital Med Lav Ergon 24:99-111. 2002
  43. ncbi request reprint [Environmental monitoring of volatile organic compounds and metallic elements in two analysis laboratories]
    Roberto Bergonzi
    Dipartimento di Medicina Sperimentale ed Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 33:387-93. 2011
    ..The determination of measurable levels of toxic and potentially carcinogenic compounds in office rooms may be of interest for personnel not specifically engaged to handle chemicals...
  44. doi request reprint Distribution of persistent organochlorine pollutants in maternal and foetal tissues: data from an Italian polluted urban area
    Roberto Bergonzi
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Chemosphere 76:747-54. 2009
    ..Maternal serum levels of these pollutants can allow a reliable estimation of organochlorine compound body burden, and can be useful markers of prenatal exposure, given their relationships with placental and umbilical cord serum levels...
  45. ncbi request reprint Metallic elements in lung tissues: results of a meta-analysis
    Simona Catalani
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Brescia, Italy
    Acta Biomed 79:52-63. 2008
    ..Such a variability of measures, combined with the very low metal concentrations calls for the definition and use of standardized procedures of sample collection, storage, and analysis...
  46. ncbi request reprint Metallic elements in pulmonary biopsies from lung cancer and control subjects
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, Section of Industrial Hygiene, University of Brescia, Brescia, Italy
    Acta Biomed 79:43-51. 2008
    ..The role of past environmental-occupational exposures could not be fully elucidated, due to the limited sample size and the retrospective nature of the study...
  47. ncbi request reprint Elements in environmental and occupational medicine
    Pietro Apostoli
    Institute of Occupational Medicine and Industrial Hygiene, University of Brescia, Brescia, Italy
    J Chromatogr B Analyt Technol Biomed Life Sci 778:63-97. 2002
    ....
  48. ncbi request reprint [Work-related musculoskeletal disorders of the upper extremity in spinning: lack of risk or of adequate methods for assessing risk?]
    E Sala
    Dipartimento di Medicina Sperimentale ed Applicata, Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 27:8-20. 2005
    ..e. the shoulder. Finally attention was paid to evaluate psychosocial factors which appear to be important when biomechanical factors are low-lying...
  49. ncbi request reprint Isomer-specific activity of dichlorodyphenyltrichloroethane with estrogen receptor in adult and suckling estrogen reporter mice
    D Di Lorenzo
    3rd Laboratory Biotechnology, Civic Hospital of Brescia, University of Brescia, 25123 Brescia, Italy
    Endocrinology 143:4544-51. 2002
    ..The ERE-tkLUC mouse proves to be a suitable tool to functionally assess the tissue specificity of estrogenic/antiestrogenic compounds in adult (as well as in suckling) mice...
  50. ncbi request reprint A comparative in vitro study of the toxic potency of five inorganic lead compounds on a rat liver epithelial cell line (REL)
    M F Aleo
    Unit of Biochemistry, School of Medicine, University of Brescia, Department of Biomedical Sciences and Biotechnologies, Viale Europa 11, 25123 Brescia, Italy
    Toxicol In Vitro 20:874-81. 2006
    ....
  51. ncbi request reprint Metabolism of arsenic after acute occupational arsine intoxication
    P Apostoli
    Institute of Occupational Health, University of Brescia, Italy
    J Toxicol Environ Health 52:331-42. 1997
    ..Furthermore, the elimination rate of As from blood follows a three-phase model and the half-lives of different species vary from about 27 to 86 h with the following gradient As5+ < MMA < As3+ < DMA < AsB...
  52. ncbi request reprint The effect of lead on male fertility: a time to pregnancy (TTP) study
    P Apostoli
    Institute of Occupational Health, University of Brescia I, P le Spedali Civili, 1 25125 Brescia, Italy
    Am J Ind Med 38:310-5. 2000
    ....
  53. ncbi request reprint Urinary beryllium--a suitable tool for assessing occupational and environmental beryllium exposure?
    P Apostoli
    Institute of Occupational Health and Industrial Hygiene, University of Brescia, Brescia, Italy
    Int Arch Occup Environ Health 74:162-6. 2001
    ..The aim of this study was to correlate Be air concentrations and Be urinary levels to ascertain whether the biological indicator was suitable for assessing occupational exposure to the metal...
  54. ncbi request reprint Assessment of reference values for mercury in urine: the results of an Italian polycentric study
    P Apostoli
    Institute of Occupational Health and Industrial Hygiene, University of Brescia, Italy
    Sci Total Environ 289:13-24. 2002
    ....
  55. ncbi request reprint Antioxidant potential and gap junction-mediated intercellular communication as early biological markers of mercuric chloride toxicity in the MDCK cell line
    M F Aleo
    Department of Biochemical Sciences, Unit of Biochemistry, School of Medicine, University of Brescia, Via Valsabbina, 19, 25123 Brescia, Italy
    Toxicol In Vitro 16:457-65. 2002
    ..1-10 microM) HgCl(2) concentrations affect either the antioxidant defences of MDCK cells or their GJIC, indicate these critical functions as suitable biological targets of early mercury-induced tubular cell injury...
  56. ncbi request reprint [Risk assessment for upper extremity work related muscoloskeletal disorders in different manufactures by applying six methods of ergonomic analysis]
    E Sala
    Dipartimento di Medicina Sperimentale ed Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 32:162-73. 2010
    ....
  57. doi request reprint Analysis of crystalline phases in airborne particulate matter by two-dimensional X-ray diffraction (XRD2)
    E Bontempi
    Laboratorio di Chimica per le Tecnologie, Universita degli Studi di Brescia, Italy
    J Environ Monit 10:82-8. 2008
    ..The first results of these experiments are very promising, showing the presence of unexpected compounds in the particulate matter of the investigated area...
  58. ncbi request reprint Long-term exposure to "low levels" of manganese oxides and neurofunctional changes in ferroalloy workers
    R Lucchini
    Institute of Occupational Health, University of Brescia, Italy
    Neurotoxicology 20:287-97. 1999
    ..In order to be protective for the entire working life, the average annual exposure level should be lower than 100 micrograms/m3...
  59. ncbi request reprint [Risk assessment of biomechanical load for the upper limbs in housework]
    Emma Sala
    Dipartimento di Medicina Sperimentale ed Applicata, Medicina del Lavoro e Igiene Industriale, Laboratorio di Igiene Industriale, Universita degli Studi di Brescia, Italy
    Med Lav 98:232-51. 2007
    ..There are few studies in the literature on work-related musculoskeletal disorders among housewives, also due to the difficulties encountered during risk assessment...
  60. ncbi request reprint Arsenic and porphyrins
    P Apostoli
    Institute of Occupational Health and Industrial Hygiene, University of Brescia, Italy
    Am J Ind Med 42:180-7. 2002
    ..To evaluate the possible effect of inorganic arsenic (iAs) and of its species on the urinary excretion of porphyrin homologues...
  61. doi request reprint Total reflection X-ray fluorescence (TXRF) for direct analysis of aerosol particle samples
    E Bontempi
    Chemistry for Technologies Laboratory, University of Brescia, via Branze 38, 25123 Brescia, Italy
    Environ Technol 31:467-77. 2010
    ..In addition, the low detection limits for many elements (low ng/cm2) indicate that this method may hold promise in various application fields, such as nanotechnology...
  62. doi request reprint Loads of housework? Biomechanical assessments of the upper limbs in women performing common household tasks
    Pietro Apostoli
    Dipartimento di Medicina Sperimentale ed Applicata, Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Brescia, Italy
    Int Arch Occup Environ Health 85:421-5. 2012
    ..Little is known about the entity of biomechanical exposure to the upper limbs during typical housework tasks. This study aims to make an initial quantitative estimate of some such exposures...
  63. doi request reprint Lack of correlation between metallic elements analyzed in hair by ICP-MS and autism
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Piazzale Spedali Civili 1, Brescia, Italy
    J Autism Dev Disord 42:342-53. 2012
    ..A slight association was found for lead only, but it was very weak, as strictly dependent on the worst data from one study...
  64. doi request reprint Toxicokinetics and toxicodynamics of elemental mercury following self-administration
    Giuseppe De Palma
    Department of Experimental and Applied Medicine, Section of Industrial Hygiene, University of Brescia, Brescia, Italy
    Clin Toxicol (Phila) 46:869-76. 2008
    ..Intravenous injection of mercury has seldom been reported, especially in cases of attempted suicide, and is associated with variable clinical outcomes...
  65. ncbi request reprint Training in safer and healthier patient handling techniques
    Angela Carta
    University of Brescia, Brescia, Italy
    Br J Nurs 19:576-82. 2010
    ..It also allowed a network of internal trainer nurses to be set up, who enabled the implementation of safer and healthier working techniques in nursing staff...
  66. ncbi request reprint Multielemental analysis of tissues from Cangrande della Scala, Prince of Verona, in the 14th century
    Pietro Apostoli
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Brescia, Italy
    J Anal Toxicol 33:322-7. 2009
    ..The low arsenic and chromium levels in the Prince's tissues as compared to modern people would be suggestive of raised concentrations of both the elements in the present era, which are likely due to industrial pollution...
  67. ncbi request reprint [On the legislative decree of 25/02: planned and necessary health surveillance for chemical risks]
    P Apostoli
    Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia
    G Ital Med Lav Ergon 25:3-11. 2003
  68. ncbi request reprint Blood lead reference values: the results of an Italian polycentric study
    P Apostoli
    Institute of Occupational Health and Industrial Hygiene, University of Brescia, Italy
    Sci Total Environ 287:1-11. 2002
    ..The main variables influencing B-Pb levels were gender, age, BMI, outside sport practice, alcohol consumption and smoking habits, while the geographic area and the urban residence did not affect the metal concentration in blood...
  69. doi request reprint High doses of cobalt induce optic and auditory neuropathy
    Pietro Apostoli
    Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Italy
    Exp Toxicol Pathol 65:719-27. 2013
    ..Moreover, we have identified the major element mediating neurotoxicity to be cobalt, although the molecular mechanisms mediating this toxicity still have to be defined. ..
  70. ncbi request reprint [Lead: indicators of dose and effects on heme]
    G Neri
    Dipartimento di Medicina Sperimentale ed Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 27:15-21. 2005
    ....
  71. ncbi request reprint [Musculoskeletal disorders caused by repetitive trauma of the upper limbs: a paradigm of the development of occupational diseases and industrial medicine]
    P Apostoli
    Cattedra di Igiene Industriale,
    G Ital Med Lav Ergon 23:87-98. 2001
    ..Finally attention would be paid to the strategy for prevention, implementing ergonomic programmes, health surveillance, adequate training to work, aimed to primary prevention of WMSDs...
  72. ncbi request reprint Metanalytical assessment of reference values for polychlorinated biphenyl in human blood
    A Mangili
    Institute of Occupational Health and Industrial Hygiene, University of Brescia, Italy
    G Ital Med Lav Ergon 26:3-11. 2004
    ....
  73. ncbi request reprint [The risk assessment procedures from SIMLII guidelines on upper extremity musculoskeletal disorders: discussion on results about a casistic from different working conditions]
    E Sala
    Dipartimento di Medicina Sperimentale e Applicata, Sezione di Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia, p le Spedali Civili 1, 25123 Brescia, Italy
    G Ital Med Lav Ergon 30:20-5. 2008
    ..It is confirmed that the application of more than one method for risk assessment, enable to better measure the risk and to focus the specific risk factors (frequency, posture, force, complementary factors)...
  74. ncbi request reprint Whole body action of xenoestrogens with different chemical structures in estrogen reporter male mice
    M Penza
    3rd Laboratory Biotechnology, Civic Hospital of Brescia, Brescia 25123, Italy
    Toxicology 205:65-73. 2004
    ..Moreover, we show that this mouse model is suitable to detect the estrogenic activity of chemicals with variable structures such as alkyl phenols and polychlorobiphenyls...
  75. ncbi request reprint Endogenous thiols and MRP transporters contribute to Hg2+ efflux in HgCl2-treated tubular MDCK cells
    Maria Francesca Aleo
    Unit of Biochemistry, Department of Biomedical Sciences and Biotechnologies, School of Medicine, University of Brescia, Viale Europa, 11, 25123 Brescia, Italy
    Toxicology 206:137-51. 2005
    ..Our results demonstrate that, in MDCK cells, inorganic Hg(2+) promotes the activation of specific detoxifying pathways that may, at least partly, depend on the activity of MRP transporters...
  76. pmc The role of albumin in human toxicology of cobalt: contribution from a clinical case
    Simona Catalani
    Section of Occupational Health and Industrial Hygiene, Department of Experimental and Applied Medicine, University of Brescia, p le Spedali Civili 1, 25123 Brescia, Italy
    ISRN Hematol 2011:690620. 2011
    ..This appears an interesting starting point for further investigations for identifying and better understanding cobalt neurotoxicity, apparently not so frequent in occupational medicine and clinical practice...
  77. ncbi request reprint Health conditions of bus drivers in a 6 year follow up study
    G Costa
    Institute of Occupational Medicine and Industrial Hygiene, Brescia, Italy
    J Hum Ergol (Tokyo) 30:405-10. 2001
    ..The comparison of the same cohort of 108 persons examined both in 1993 and in 1999 showed a significant increase of low back pain, gastrointestinal troubles, haemorrhoids and lipids disorders...
  78. ncbi request reprint [Reference values necessary for the interpretation of biological surveillance]
    P Apostoli
    Cattedra di Igiene Industriale, Universita degli Studi di Brescia
    G Ital Med Lav Ergon 25:22-7. 2003
    ....
  79. ncbi request reprint [Inorganic lead stimulates endothelin secretion in the MDCK cell line]
    R Giuliani
    Sezione di Biochimica e Chimica Clinica, Facolta di Medicina e Chirurgia, Universita degli Studi di Brescia, Italy
    G Ital Med Lav Ergon 27:73-9. 2005
    ..In vivo studies demonstrated that rats chronically exposed to Pb low levels exhibited blood pressure elevation coupled with an increase of ET-3 concentration in plasma and urine in comparison with control animals...
  80. ncbi request reprint [Can exposure to low doses have effects?]
    P Apostoli
    Dipartimento di Medicina Sperimentale ed Applicata, Medicina del Lavoro e Igiene Industriale, Universita degli Studi di Brescia
    G Ital Med Lav Ergon 25:310-9. 2003
    ..The Authors conclude therefore that to ensure the protection of all the workers' health and safety, the clinical, toxicological and epidemiological expertise of the occupational physician appears to be fundamental and unreplacable...
  81. ncbi request reprint [Environmental and biological monitoring of exposure to polycyclic aromatic hydrocarbons in workers of an electric steel foundry]
    E Bergamaschi
    Dipartimento di Clinica Medica, Nefrologia e Scienze della Prevenzione, Sezione di Medicina del Lavoro e Tossicologia Industriale, Universita degli Studi di Parma
    Med Lav 96:390-402. 2005
    ..To assess and classify exposure to Polycyclic Aromatic Hydrocarbons (PAHs) in some specific working areas of a steel foundry operating with a continuous casting process and evaluate biomonitoring data in different job tasks...
  82. ncbi request reprint [Biological monitoring: concepts and applications in public health]
    F Pivetta
    , , , Rio de Janeiro, RJ, 21041-210, Brasil
    Cad Saude Publica 17:545-54. 2001
    ....
  83. ncbi request reprint [Data quality and the interpretation of biological monitoring results]
    P Manini
    Centro Studi e Ricerche ISPESL presso l Università di Parma
    G Ital Med Lav Ergon 26:324-30. 2004
    ....
  84. pmc Time To Pregnancy and occupational lead exposure
    M Joffe
    Imperial College Faculty of Medicine, Department of Epidemiology and Public Health, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Occup Environ Med 60:752-8. 2003
    ..Lead exposure is known to be harmful to the male reproductive system, including impairment of fertility. However, it is unclear whether currently existing low levels of exposure have this effect...
  85. pmc Sperm count and chromatin structure in men exposed to inorganic lead: lowest adverse effect levels
    J P Bonde
    Department of Occupational Medicine, University Hospital of Aarhus, Denmark
    Occup Environ Med 59:234-42. 2002
    ..To obtain knowledge on male reproductive toxicity of inorganic lead at current European exposure levels and to establish lowest adverse effect levels, if any...
  86. ncbi request reprint [New biomarkers of exposure]
    P Apostoli
    Dipartimento di Medicina Sperimentale ed Applicata, Medicina del Lavoro ed Igiene Industriale Università degli Studi di Brescia
    G Ital Med Lav Ergon 26:278-97. 2004
    ..We conclude that development of this specific field of research appears to be a crucial point for future improvement in risk assessment and health surveillance procedures...
  87. ncbi request reprint [In vitro study of the nephrotoxic mechanism of mercuric chloride]
    M F Aleo
    Sezione di Biochimica e Chimica Clinica, Facolta di Medicina e Chirurgia, Universita degli Studi di Brescia, Italia
    Med Lav 93:267-78. 2002
    ....
  88. pmc Any need to revisit the male reproductive toxicity of lead?
    J P Bonde
    Occup Environ Med 62:2-3. 2005
  89. ncbi request reprint [Occupational medicine faces new health challenges: the example of alcohol dependence]
    M M Ferrario
    Med Lav 98:443-5. 2007
    ..Due to these difficulties in the application of the new regulations, field trials become all the more important, since they offer the possibility of assessing efficacy and efficiency of the different approaches...
  90. ncbi request reprint [Heme oxygenase 1 expression in foundry workers]
    P Mozzoni
    Universita di Parma, Dipartimento di Clinica Medica, Nefrologia e Scienze della Prevenzione, Parma
    G Ital Med Lav Ergon 27:322-5. 2005
    ....
  91. ncbi request reprint [Exposure to arsenic in the manufacture of glass rods. Results of the biological monitoring and preventive indications]
    R Montagnani
    Dipartimento di prevenzione Spsal Ulss 12 Venezia
    G Ital Med Lav Ergon 28:158-62. 2006
    ..We propose further measures to reduce this risk...
  92. ncbi request reprint [Does the decree 25/2002 still guarantee the health care of workers exposed to lead?]
    P Apostoli
    Medicina del Lavoro ed Igiene Industriale, Universita degli Studi di Brescia
    G Ital Med Lav Ergon 24:355-60. 2002
  93. ncbi request reprint [Anemia in workers exposed to lead: update on differential diagnosis]
    L Di Lorenzo
    Dipartimento di Medicina Interna e Medicina Pubblica, Sezione di Medicina del Lavoro, Universita di Bari, Italy
    G Ital Med Lav Ergon 27:54-61. 2005
    ..Moreover a diagnostic algorithm was developed based on literature that seems to be able to discriminate lead poisoning from other causes of anemia in lead exposed workers in this study...
  94. ncbi request reprint [Survey on educational needs in occupational medicine in Italy]
    S Iavicoli
    ISPESL Istituto Superiore per la Prevenzione e la Sicurezza del Lavoro
    G Ital Med Lav Ergon 26:12-8. 2004
    ..In order to correctly asses the education needs and collect valid information of Occupational Physicians in Italy we administered a target questionnaire among a group of them. The results are analyzed and discussed...
  95. ncbi request reprint [Occupational Medicine Programme in the university degree on prevention techniques in living and working environments]
    F S Violante
    Colegio dei Docenti Universitari Bernardino Ramazzini della Società Italiana di Medicina del Lavoro e Igiene Industriale
    Med Lav 96:71-9. 2005
    ..Also, training of non-graduate technicians working for local health authorities is discussed...
  96. ncbi request reprint [ALAD polymorphism and indicators of dose and effects of occupational exposure to inorganic lead]
    G De Palma
    Dipartimento di Clinica Medica, Nefrologia e Scienze della Prevenzione, Universita degli Studi di Parma, Italy
    G Ital Med Lav Ergon 27:39-42. 2005
    ..Results confirm previous studies, supporting the hypothesis that ALAD polymorphism may interfere with toxico-kinetic and toxico-dynamic parameters of occupational exposure to Pb...
  97. ncbi request reprint [Reduced thymulin production during occupational exposure to lead]
    L Santarelli
    Clinica di Medicina del Lavoro, Università Politecnica delle Marche Ancona
    G Ital Med Lav Ergon 27:68-72. 2005
    ..This study opens perspectives for further research that would both confirm the results and verify the mechanisms of action of lead on thymulin either direct or indirect and the possible role of zinc...
  98. ncbi request reprint [Implementation of parliamentary act D. Lgs 25/02 and definition of "moderate risk"]
    G B Bartolucci
    G Ital Med Lav Ergon 25:336-41. 2003
    ..In conclusion, the Working Group recommend that the new law be amended in order to clarify its most controversial aspects, whose misinterpretation could severely jeopardize the protection of the workers' safety and health at work...
  99. ncbi request reprint [Excellency accreditation by the Italian Society of Occupational Medicine and Industrial Hygiene (SIMLII)]
    G Abbritti
    Dipartimento di Medicina Clinica e Sperimentale, Istituto di Medicina del Lavoro Università di Perugia, Via E dal Pozzo, 06122 Perugia
    Med Lav 94:413-20. 2003
    ....
  100. ncbi request reprint Needs, education and accreditation in occupational medicine in Italy
    G Abbritti
    Institute of Occupational Medicine and Environmental and Occupational Toxicology, University of Perugia, Perugia, Italy
    Int Arch Occup Environ Health 78:75-8. 2005
    ..S.P.E.S.L.), which enquired into their training and continuing education needs. The programme started in 2003, and its first edition-presented here-involved more than 400 physicians specialising in occupational health...
  101. ncbi request reprint [The guidelines and other scientific technical instruments for improving, updating and validating the Occupational Physician activities]
    P Apostoli
    G Ital Med Lav Ergon 30:5-13. 2008
    ....