Pasquale Annunziata

Summary

Affiliation: University of Siena
Country: Italy

Publications

  1. pmc Expression of Tight Junction and Drug Efflux Transporter Proteins in an in vitro Model of Human Blood-Brain Barrier
    Chiara Cioni
    Department of Neurological, Neurosurgical and Behavioral Sciences, University of Siena Siena, Italy
    Front Psychiatry 3:47. 2012
  2. ncbi request reprint Immunosuppressive monoclonal antibody to CD64 from patients with long-term stable multiple sclerosis
    P Annunziata
    Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy
    J Neuroimmunol 256:62-70. 2013
  3. doi request reprint Clinical features of Sjogren's syndrome in patients with multiple sclerosis
    P Annunziata
    Department of Neurological, Neurosurgical and Behavioural Sciences, University of Siena, Siena, Italy
    Acta Neurol Scand 124:109-14. 2011
  4. ncbi request reprint High levels of cerebrospinal fluid IgM binding to myelin basic protein are associated with early benign course in multiple sclerosis
    P Annunziata
    Institute of Neurological Sciences, University of Siena, Italy
    J Neuroimmunol 77:128-33. 1997
  5. ncbi request reprint Absence of cerebrospinal fluid oligoclonal bands is associated with delayed disability progression in relapsing-remitting MS patients treated with interferon-beta
    Pasquale Annunziata
    Department of Neurological Sciences and Behaviour, University of Siena, Italy
    J Neurol Sci 244:97-102. 2006
  6. ncbi request reprint High frequency of psoriasis in relatives is associated with early onset in an Italian multiple sclerosis cohort
    P Annunziata
    Department of Neurological Sciences and Behaviour, University of Siena, Siena, Italy
    Acta Neurol Scand 108:327-31. 2003
  7. ncbi request reprint Blood-brain barrier changes during invasion of the central nervous system by HIV-1. Old and new insights into the mechanism
    Pasquale Annunziata
    Dipartimento di Scienze Neurologiche e del Comportamento, Centro per lo Studio della Sclerosi multipla e delle Malattie Neuroimmunologiche, Universita di Siena, Viale Bracci, 2, 53100 Siena, Italy
    J Neurol 250:901-6. 2003
  8. ncbi request reprint Early synthesis and correlation of serum anti-thyroid antibodies with clinical parameters in multiple sclerosis
    P Annunziata
    Institute of Neurological Sciences, Viale Bracci, 2, University of Siena, 53100, Siena, Italy
    J Neurol Sci 168:32-6. 1999
  9. ncbi request reprint Association of anti-GM1 antibodies but not of anti-cytomegalovirus, Campylobacter jejuni and Helicobacter pylori IgG, with a poor outcome in Guillain-Barré syndrome
    Pasquale Annunziata
    Department of Neurological Sciences and Behaviour, University of Siena, Viale Bracci 2, 53100 Siena, Italy
    J Neurol Sci 213:55-60. 2003
  10. ncbi request reprint Substance P antagonist blocks leakage and reduces activation of cytokine-stimulated rat brain endothelium
    Pasquale Annunziata
    Institute of Neurological Sciences, University of Siena, Viale Bracci, 2, 53100, Siena, Italy
    J Neuroimmunol 131:41-9. 2002

Collaborators

Detail Information

Publications20

  1. pmc Expression of Tight Junction and Drug Efflux Transporter Proteins in an in vitro Model of Human Blood-Brain Barrier
    Chiara Cioni
    Department of Neurological, Neurosurgical and Behavioral Sciences, University of Siena Siena, Italy
    Front Psychiatry 3:47. 2012
    ....
  2. ncbi request reprint Immunosuppressive monoclonal antibody to CD64 from patients with long-term stable multiple sclerosis
    P Annunziata
    Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy
    J Neuroimmunol 256:62-70. 2013
    ....
  3. doi request reprint Clinical features of Sjogren's syndrome in patients with multiple sclerosis
    P Annunziata
    Department of Neurological, Neurosurgical and Behavioural Sciences, University of Siena, Siena, Italy
    Acta Neurol Scand 124:109-14. 2011
    ....
  4. ncbi request reprint High levels of cerebrospinal fluid IgM binding to myelin basic protein are associated with early benign course in multiple sclerosis
    P Annunziata
    Institute of Neurological Sciences, University of Siena, Italy
    J Neuroimmunol 77:128-33. 1997
    ....
  5. ncbi request reprint Absence of cerebrospinal fluid oligoclonal bands is associated with delayed disability progression in relapsing-remitting MS patients treated with interferon-beta
    Pasquale Annunziata
    Department of Neurological Sciences and Behaviour, University of Siena, Italy
    J Neurol Sci 244:97-102. 2006
    ..04). The absence of OB and low number of baseline T2-weighted lesions in this cohort of MS patients are favourable prognostic factors influencing the clinical response to IFN-beta treatment in RRMS patients...
  6. ncbi request reprint High frequency of psoriasis in relatives is associated with early onset in an Italian multiple sclerosis cohort
    P Annunziata
    Department of Neurological Sciences and Behaviour, University of Siena, Siena, Italy
    Acta Neurol Scand 108:327-31. 2003
    ..An exploratory study has been carried out to assess the association of autoimmune diseases in multiple sclerosis (MS) families with clinical features and disability of MS patients...
  7. ncbi request reprint Blood-brain barrier changes during invasion of the central nervous system by HIV-1. Old and new insights into the mechanism
    Pasquale Annunziata
    Dipartimento di Scienze Neurologiche e del Comportamento, Centro per lo Studio della Sclerosi multipla e delle Malattie Neuroimmunologiche, Universita di Siena, Viale Bracci, 2, 53100 Siena, Italy
    J Neurol 250:901-6. 2003
    ..Several issues deserve further investigation and answers to these questions may provide keys for new therapeutic strategies in HIV-1 infection of the central nervous system...
  8. ncbi request reprint Early synthesis and correlation of serum anti-thyroid antibodies with clinical parameters in multiple sclerosis
    P Annunziata
    Institute of Neurological Sciences, Viale Bracci, 2, University of Siena, 53100, Siena, Italy
    J Neurol Sci 168:32-6. 1999
    ..Furthermore, high titres of anti-thyroglobulin antibodies are associated with low disability scores, suggesting a possible protective role of these antibodies that deserves further investigation...
  9. ncbi request reprint Association of anti-GM1 antibodies but not of anti-cytomegalovirus, Campylobacter jejuni and Helicobacter pylori IgG, with a poor outcome in Guillain-Barré syndrome
    Pasquale Annunziata
    Department of Neurological Sciences and Behaviour, University of Siena, Viale Bracci 2, 53100 Siena, Italy
    J Neurol Sci 213:55-60. 2003
    ..These findings provide further evidence that the level of circulating anti-GM1 IgG plays a role in determining recovery from disability in GBS patients irrespective of other IgG against microorganisms causing infections preceding GBS...
  10. ncbi request reprint Substance P antagonist blocks leakage and reduces activation of cytokine-stimulated rat brain endothelium
    Pasquale Annunziata
    Institute of Neurological Sciences, University of Siena, Viale Bracci, 2, 53100, Siena, Italy
    J Neuroimmunol 131:41-9. 2002
    ..These in vitro findings demonstrate that substance P plays a major pathogenetic role in damaging and activating the BBB vascular component in the presence of proinflammatory cytokines...
  11. doi request reprint Higher expression of BDNF receptor gp145trkB is associated with lower apoptosis intensity in T cell lines in multiple sclerosis
    Lorenzo De Santi
    Department of Neurological and Behavioural Sciences, University of Siena, Siena, Italy
    J Neurol Sci 277:65-70. 2009
    ..These findings suggest that gp145trkB is mainly expressed on T cell lines from MS patients and that the BDNF/gp145trkB axis is involved in the regulation of peripheral T cell apoptosis in MS...
  12. ncbi request reprint Circulating gp120 alters the blood-brain barrier permeability in HIV-1 gp120 transgenic mice
    Chiara Cioni
    Istituto di Scienze Neurologiche, Universita di Siena, Viale Bracci, 2, 53100 Siena, Italy
    Neurosci Lett 330:299-301. 2002
    ..This permeability was neutralized after immunoabsorption of sera with anti-gp120 monoclonal antibody. These findings demonstrate that the blood-brain barrier alteration in HIV-1 gp120 transgenic mice is due to circulating gp120...
  13. doi request reprint Impairment of vertical saccades from an acute pontine lesion in multiple sclerosis
    Alessandra Rufa
    Department of Neurological and Behavioural Sciences, Neuroradiology Unit, S Maria alle Scotte Hospital, Siena, Italy
    J Neuroophthalmol 28:305-7. 2008
    ..Our patient verifies the fact that vertical saccadic abnormalities may occur from a lesion apparently confined to the pons...
  14. ncbi request reprint Successful response of non-recovering Ramsay Hunt syndrome to intravenous high dose methylprednisolone
    Donatella Donati
    Department of Neurological, Neurosurgical and Behavioural Sciences, University of Siena, Italy
    J Neurol Sci 318:160-2. 2012
    ....
  15. doi request reprint Transient supranuclear paresis of the abduction in viral encephalitis of the brainstem
    Alessandra Rufa
    Dipartimento di Scienze Neurologiche e del Comportamento, Universita di Siena, Viale Bracci 2, 53100, Siena, Italy
    Neurol Sci 31:653-5. 2010
    ..PCR analysis of cerebrospinal fluid showed an enterovirus infection. Spontaneous clinical recovery rapidly occurred 2 days after onset. The brainstem lesion was undetectable at 5-week brain MRI follow-up...
  16. ncbi request reprint Symptomatic cranial neuralgias in multiple sclerosis: clinical features and treatment
    Lorenzo De Santi
    Department of Neurological, Neurosurgical and Behavioural Sciences, University of Siena, Siena, Italy
    Clin Neurol Neurosurg 114:101-7. 2012
    ....
  17. doi request reprint Clinical-radiologic heterogeneity of occipital neuralgiform pain as multiple sclerosis relapse
    Lorenzo De Santi
    Neurological and Behavioral Sciences, University of Siena, Siena, Italy
    Headache 49:304-7. 2009
    ..We suggest that sudden paroxysmal occipital pain may signal relapse of MS and cervical MRI with gadolinium should be considered; these patients show good clinical response to high-dose intravenous corticosteroids...
  18. ncbi request reprint Acute transverse myelitis and hepatitis C virus
    Pasquale Annunziata
    Department of Neurological Sciences and Behaviour, Centre for Research on Multiple Sclerosis and Neuroimmunological Diseases, University of Siena, Siena, Italy
    Infez Med 13:45-7. 2005
    ..This finding suggests that in acute myelitis of unknown aetiology, testing CSF for HCV RNA and related antibodies is warranted...
  19. doi request reprint Expression of preprotachykinin-A mRNA isoforms and substance P production in T lymphocytes of human healthy subjects
    Loredana Cantalupo
    Department of Neurological and Behavioural Sciences, University of Siena, Siena, Italy
    Neurosci Lett 434:191-4. 2008
    ..001). These findings provide evidence of a heterogeneous expression of PPT-A isoforms in CD3+ lymphocytes of normal healthy subjects...
  20. ncbi request reprint Long time interval between multiple sclerosis onset and occurrence of primary Sjögren's syndrome in a woman treated with interferon-beta
    L De Santi
    Department of Neurological and Behavioural Sciences, University of Siena, Siena, Italy
    Acta Neurol Scand 112:194-6. 2005
    ..Although there are no evidences about a possible role of IFN-beta in triggering SS yet, a screening for clinical and laboratory signs of SS should be assessed in MS patients during IFN-beta treatment...