Mario Angelico

Summary

Affiliation: University of Rome Tor Vergata
Country: Italy

Publications

  1. ncbi request reprint Amantadine monotherapy is ineffective in the treatment of hepatitis C virus recurrence in the post-liver transplantation setting
    F Muzi
    Liver Transplant Unit, Tor Vergata University of Rome, Surgical Clinic, S Eugenio Hospital, Rome, Italy
    Transplant Proc 37:1705-7. 2005
  2. ncbi request reprint Failure of a reinforced triple course of hepatitis B vaccination in patients transplanted for HBV-related cirrhosis
    Mario Angelico
    Gastroenterology Unit, Department of Public Health, and Liver Transplantation Center, Department of Surgery, University of Rome Tor Vergata, Medical School, Rome, Italy
    Hepatology 35:176-81. 2002
  3. doi request reprint Massive hepatic angiomyolipoma in a young woman with tuberous sclerosis complex: significant clinical improvement during tamoxifen treatment
    Ilaria Lenci
    Liver Unit, Tor Vergata University, Viale Oxford 81, 00133 Rome, Italy
    J Hepatol 48:1026-9. 2008
  4. doi request reprint Hepatitis B-core antibody positive donors in liver transplantation and their impact on graft survival: evidence from the Liver Match cohort study
    Mario Angelico
    Liver Unit, Tor Vergata University, Rome, Italy
    J Hepatol 58:715-23. 2013
  5. ncbi request reprint A randomized controlled trial of amantadine plus interferon-alpha2a vs. interferon-alpha2a alone in naive patients with chronic hepatitis C randomized according to the early virological response to interferon-alpha2a monotherapy
    M Angelico
    Gastroenterology and Hepatology Clinics, University of Rome Tor Vergata University of Rome La Sapienza S Giacomo Hospital, Rome, Italy
    Aliment Pharmacol Ther 19:339-47. 2004
  6. ncbi request reprint Peginterferon alpha-2a and ribavirin versus peginterferon alpha-2a monotherapy in early virological responders and peginterferon alpha-2a and ribavirin versus peginterferon alpha-2a, ribavirin and amantadine triple therapy in early virological nonresponde
    Mario Angelico
    Hepatology Unit, Tor Vergata University, Rome, Italy
    Eur J Gastroenterol Hepatol 20:680-7. 2008
  7. ncbi request reprint Practice of adult liver transplantation in Italy. Recommendations of the Italian Association for the Study of the Liver (A.I.S.F.)
    M Angelico
    Tor Vergata University of Rome, Italy
    Dig Liver Dis 37:461-7. 2005
  8. doi request reprint Liver Match, a prospective observational cohort study on liver transplantation in Italy: study design and current practice of donor-recipient matching
    Mario Angelico
    Hepatology and Liver Transplantation Unit, Tor Vergata University, Rome, Italy
    Dig Liver Dis 43:155-64. 2011
  9. ncbi request reprint A randomized study on Peg-interferon alfa-2a with or without ribavirin in liver transplant recipients with recurrent hepatitis C
    Mario Angelico
    Hepatology Unit, Tor Vergata University, Rome, Italy
    J Hepatol 46:1009-17. 2007
  10. ncbi request reprint Epidemiology and outcome of hepatitis C relapse in transplant recipients
    M Angelico
    Dipartimento di Medicina Interna, Universita Tor Vergata, Hepatology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy
    Transplant Proc 43:2457-8. 2011

Detail Information

Publications73

  1. ncbi request reprint Amantadine monotherapy is ineffective in the treatment of hepatitis C virus recurrence in the post-liver transplantation setting
    F Muzi
    Liver Transplant Unit, Tor Vergata University of Rome, Surgical Clinic, S Eugenio Hospital, Rome, Italy
    Transplant Proc 37:1705-7. 2005
    ..Amantadine (Am) is currently under evaluation. The aim of this study was to assess the safety and the effectiveness of Am monotherapy in LT patients with HCV recurrence...
  2. ncbi request reprint Failure of a reinforced triple course of hepatitis B vaccination in patients transplanted for HBV-related cirrhosis
    Mario Angelico
    Gastroenterology Unit, Department of Public Health, and Liver Transplantation Center, Department of Surgery, University of Rome Tor Vergata, Medical School, Rome, Italy
    Hepatology 35:176-81. 2002
    ..In conclusion, a highly reinforced HBV vaccination program is effective only in a few patients who had liver transplants for HBV-related cirrhosis...
  3. doi request reprint Massive hepatic angiomyolipoma in a young woman with tuberous sclerosis complex: significant clinical improvement during tamoxifen treatment
    Ilaria Lenci
    Liver Unit, Tor Vergata University, Viale Oxford 81, 00133 Rome, Italy
    J Hepatol 48:1026-9. 2008
    ..Because of their slow growth, these tumors are often asymptomatic. Since AMLs express estrogen and progesteron receptors we suggest the possible benefits of tamoxifen for the treatment of liver AMLs...
  4. doi request reprint Hepatitis B-core antibody positive donors in liver transplantation and their impact on graft survival: evidence from the Liver Match cohort study
    Mario Angelico
    Liver Unit, Tor Vergata University, Rome, Italy
    J Hepatol 58:715-23. 2013
    ..The appropriate allocation of grafts from HBcAb positive donors in liver transplantation is crucial, yet a consensus is still lacking...
  5. ncbi request reprint A randomized controlled trial of amantadine plus interferon-alpha2a vs. interferon-alpha2a alone in naive patients with chronic hepatitis C randomized according to the early virological response to interferon-alpha2a monotherapy
    M Angelico
    Gastroenterology and Hepatology Clinics, University of Rome Tor Vergata University of Rome La Sapienza S Giacomo Hospital, Rome, Italy
    Aliment Pharmacol Ther 19:339-47. 2004
    ..An early virological response to interferon-alpha treatment is a strong predictor of sustained response, but it has never been exploited to stratify patients in clinical trials...
  6. ncbi request reprint Peginterferon alpha-2a and ribavirin versus peginterferon alpha-2a monotherapy in early virological responders and peginterferon alpha-2a and ribavirin versus peginterferon alpha-2a, ribavirin and amantadine triple therapy in early virological nonresponde
    Mario Angelico
    Hepatology Unit, Tor Vergata University, Rome, Italy
    Eur J Gastroenterol Hepatol 20:680-7. 2008
    ....
  7. ncbi request reprint Practice of adult liver transplantation in Italy. Recommendations of the Italian Association for the Study of the Liver (A.I.S.F.)
    M Angelico
    Tor Vergata University of Rome, Italy
    Dig Liver Dis 37:461-7. 2005
    ....
  8. doi request reprint Liver Match, a prospective observational cohort study on liver transplantation in Italy: study design and current practice of donor-recipient matching
    Mario Angelico
    Hepatology and Liver Transplantation Unit, Tor Vergata University, Rome, Italy
    Dig Liver Dis 43:155-64. 2011
    ..In this report we describe the study methodology and provide a cross-sectional description of donor and recipient characteristics and of graft allocation...
  9. ncbi request reprint A randomized study on Peg-interferon alfa-2a with or without ribavirin in liver transplant recipients with recurrent hepatitis C
    Mario Angelico
    Hepatology Unit, Tor Vergata University, Rome, Italy
    J Hepatol 46:1009-17. 2007
    ..We performed a randomized trial on pegylated interferon alfa-2a (Peg-IFNalpha) monotherapy vs Peg-IFNalpha and ribavirin in non-cirrhotic liver transplant recipients with recurrent hepatitis C...
  10. ncbi request reprint Epidemiology and outcome of hepatitis C relapse in transplant recipients
    M Angelico
    Dipartimento di Medicina Interna, Universita Tor Vergata, Hepatology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy
    Transplant Proc 43:2457-8. 2011
    ..This article reviews the risk factors underlying this association and presents the current strategies used to manage HCV infections in transplant recipients...
  11. ncbi request reprint Long-acting nitrates in portal hypertension: to be or not to be?
    M Angelico
    Chair of Gastroenterology, Tor Vergata University of Rome, Italy
    Dig Liver Dis 33:205-11. 2001
    ..Whether or not nitrates may have a role in the primary and/or secondary prophylaxis of bleeding needs to be addressed in further long-term studies...
  12. ncbi request reprint One-year pilot study on tauroursodeoxycholic acid as an adjuvant treatment after liver transplantation
    M Angelico
    Department of Surgery, University of Rome Tor Vergata, Italy
    Ital J Gastroenterol Hepatol 31:462-8. 1999
    ..The usefulness of ursodeoxycholic acid after liver transplantation is controversial. Tauroursodeoxycholic acid, the natural taurine-amidate, is a highly hydrophilic and cytoprotective bile salt currently under investigation...
  13. ncbi request reprint Unfavourable effects of colchicine in combination with interferon-alpha in the treatment of chronic hepatitis C
    M Angelico
    Chairs of Gastroenterology, Department of Public Health, University of Rome Tor Vergata, Italy
    Aliment Pharmacol Ther 14:1459-67. 2000
    ..The prognosis of chronic hepatitis depends on the progression of hepatic fibrosis...
  14. ncbi request reprint Low levels of hepatitis C virus RNA in blood of infected patients under maintenance haemodialysis with high-biocompatibility, high-permeability filters
    M Angelico
    Department of Public Health and Chairs of Surgery, Tor Vergata University, Rome, Italy
    Dig Liver Dis 32:724-8. 2000
    ..We investigated whether the hepatitis C virus viral load is influenced by the haemodialytic procedure and the type of dialyser...
  15. ncbi request reprint Review article: hepatobiliary complications associated with total parenteral nutrition
    M Angelico
    Dipartimento di Sanità Publica, University of Rome Tor Vergata, and IRCCS Santa Lucia, Rome, Italy
    Aliment Pharmacol Ther 14:54-7. 2000
    ..Each potential mechanism and its clinical relevance is discussed in this review...
  16. ncbi request reprint The Tor Vergata weaning of immunosuppression protocols in stable hepatitis C virus liver transplant patients: the 10-year follow-up
    Tommaso Maria Manzia
    UOC Trapianti d Organo, Tor Vergata University, Rome 00144, Italy
    Transpl Int 26:259-66. 2013
    ..After a 10-year follow-up of a Tor Vergata weaning protocol, 6/34 patients completed follow-up without reinstitution of immunosuppression and this appeared beneficial regarding a reduction in fibrosis progression...
  17. doi request reprint Safety of complete and sustained prophylaxis withdrawal in patients liver-transplanted for HBV-related cirrhosis at low risk of HBV recurrence
    Ilaria Lenci
    Hepatology, Tor Vergata University, Rome, Italy
    J Hepatol 55:587-93. 2011
    ..HBV reactivation after liver transplantation may be related to persistence of covalently closed circular (ccc) DNA. We investigated the safety of HBV prophylaxis withdrawal in selected HBV transplanted patients...
  18. doi request reprint Long-term, maintenance MMF monotherapy improves the fibrosis progression in liver transplant recipients with recurrent hepatitis C
    Tommaso Maria Manzia
    UOC Transplant Unit, Department of Surgery, Tor Vergata University, Rome, Italy
    Transpl Int 24:461-8. 2011
    ..05 ± 0.44 in the MMF group and 0.33 ± 0.24 in the CNI group (P = 0.04). MMF monotherapy is associated with a favourable effect on hepatic fibrosis progression in HCV liver transplant recipients...
  19. doi request reprint Plasma/erythrocyte ribavirin x100 ratio as an indicator of sustained virological response in HCV genotype 1 patients with early virological response
    Leonardo Baiocchi
    Hepatology Unit, University of Rome, Rome, Italy
    Antivir Ther 15:633-9. 2010
    ..Our aim was to evaluate the usefulness of plasma and erythrocyte ribavirin levels in predicting sustained virological response (SVR) in HCV genotype 1 patients undergoing antiviral treatment...
  20. doi request reprint Maintenance ribavirin monotherapy delays fibrosis progression in liver transplant recipients with recurrent hepatitis C at high risk of progression
    Raffaella Lionetti
    Hepatology Unit, University of Rome Tor Vergata, Via Montpellier 1, Rome, Italy
    Dig Liver Dis 42:297-303. 2010
    ..Fibrosis in liver transplant recipients with recurrent HCV is fast, yet, different patterns of progression are recognized...
  21. ncbi request reprint A randomized controlled trial of sequential pegylated interferon-α and telbivudine or vice versa for 48 weeks in hepatitis B e antigen-negative chronic hepatitis B
    Paola Piccolo
    Hepatology Unit, Tor Vergata University, Rome, Italy
    Antivir Ther 18:57-64. 2013
    ..The aim of our study was to compare the efficacy and safety of two sequential regimens of pegylated interferon (PEG-IFN)-α and telbivudine (LdT)...
  22. doi request reprint Total and covalently closed circular DNA detection in liver tissue of long-term survivors transplanted for HBV-related cirrhosis
    Ilaria Lenci
    Hepatology Unit, Department of Internal Medicine, Tor Vergata University, Via Montpellier 1 00133 Rome, Italy
    Dig Liver Dis 42:578-84. 2010
    ..The risk of HBV reactivation is due to persistence of covalently closed circular (ccc) DNA in hepatocytes. Whether cccDNA persists in livers of long-term transplant survivors who received conventional prophylaxis is unknown...
  23. doi request reprint Hepatitis C virus recurrence and immunosuppression-free state after liver transplantation
    Tommaso Maria Manzia
    UOC Trapianti d Organo, Tor Vergata University, Rome, Italy
    Expert Rev Clin Immunol 8:635-44. 2012
    ....
  24. doi request reprint A randomized controlled trial of pegylated interferon-alpha2a plus adefovir dipivoxil for hepatitis B e antigen-negative chronic hepatitis B
    Paola Piccolo
    Hepatology Unit, Tor Vergata University, Rome, Italy
    Antivir Ther 14:1165-74. 2009
    ..We aimed to assess the safety and efficacy of PEG-IFN-alpha plus adefovir dipivoxil (ADV) versus PEG-IFN-alpha monotherapy for compensated HBeAg-negative CHB...
  25. doi request reprint One-year vaccination against hepatitis B virus with a MPL-vaccine in liver transplant patients for HBV-related cirrhosis
    Daniele Di Paolo
    Hepatology Unit, Department of Internal Medicine, Rome, Italy Immunoprophylaxis Center, ASL RM C, Rome, Italy
    Transpl Int 23:1105-12. 2010
    ..1%) greater than 500IU/l. One-year extended monthly vaccination with a MPL-adjuvant recombinant vaccine induces a sustained protective anti-HBs response in approximately half of transplant recipients...
  26. doi request reprint Anti-HBV treatment induces novel reverse transcriptase mutations with reflective effect on HBV S antigen
    Valeria Cento
    Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, 00100 Rome, Italy
    J Infect 67:303-12. 2013
    ..Furthermore, due to HBV-RT/HBsAg gene-overlap, they can have an impact on HBsAg-detection and quantification...
  27. ncbi request reprint Low-dose hepatitis B immunoglobulin given "on demand" in combination with lamivudine: a highly cost-effective approach to prevent recurrent hepatitis B virus infection in the long-term follow-up after liver transplantation
    Daniele Di Paolo
    Gastroenterology Unit, Department of Public Health, University of Rome Tor Vergata, Medical School, Rome, Italy
    Transplantation 77:1203-8. 2004
    ....
  28. ncbi request reprint TUDCA prevents cholestasis and canalicular damage induced by ischemia-reperfusion injury in the rat, modulating PKCalpha-ezrin pathway
    Leonardo Baiocchi
    Hepatology Unit, University of Rome Tor Vergata, Rome, Italy
    Transpl Int 21:792-800. 2008
    ..PKCalpha inhibition abolished these TUDCA effects. TUDCA administration during IRI reduces cholestasis and canalicular damage in the liver modulating PKCalpha-ezrin pathway...
  29. ncbi request reprint Cyclosporine A versus tacrolimus monotherapy. Comparison on bile lipids in the first 3 months after liver transplant in humans
    Leonardo Baiocchi
    Faculty of Medicine, University of Rome Tor Vergata, Rome, Italy
    Transpl Int 19:389-95. 2006
    ..04). This difference normalized thereafter, without any biochemical or clinical effect at 3-month follow up...
  30. ncbi request reprint Comparative evaluation of percutaneous laser and radiofrequency ablation in patients with HCC smaller than 4 cm
    Antonio Orlacchio
    Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Policlinico Universitario Tor Vergata, Viale Oxford 81, 00133, Rome, Italy
    Radiol Med 119:298-308. 2014
    ..This study was done to compare percutaneous laser ablation (PLA) and radiofrequency thermoablation (RFA) for the treatment of hepatocellular carcinoma (HCC) ≤ 4 cm, in patients with liver cirrhosis...
  31. doi request reprint Leptin attenuates ischemia-reperfusion injury in the rat liver
    Marco Carbone
    Hepatology Unit, Department of Internal Medicine, University of Tor Vergata, Via Montpellier 1, Rome, Italy
    Transpl Int 25:1282-8. 2012
    ..02; TUNEL P = 0.01; Cell death Detection assay P = 0.003). In conclusion, cold storage and reperfusion with leptin reduce liver ischemia-reperfusion injury. This effect is associated with an increased expression of pSTAT-3...
  32. doi request reprint Vitamin D3 modulates T lymphocyte responses in hepatitis C virus-infected liver transplant recipients
    Cristiana Almerighi
    Liver Transplant Unit, Department of Internal Medicine, University of Rome Tor Vergata, Rome, Italy
    Dig Liver Dis 44:67-73. 2012
    ..Aim of the present study was to investigate whether 1,25(OH)(2)D(3) (Vitamin D3) modulates T lymphocyte functions in patients transplanted for hepatitis C virus-related cirrhosis...
  33. doi request reprint Liver elasticity in NASH patients evaluated with real-time elastography (RTE)
    Antonio Orlacchio
    Department of Diagnostic Imaging, Molecular Imaging, Interventional Radiology, and Radiation Therapy, University Hospital Tor Vergata, Rome, Italy
    Ultrasound Med Biol 38:537-44. 2012
    ..92. We suggest that RTE could be used as a complementary imaging method to evaluate liver fibrosis in NASH patients. Future studies of larger patient cohorts are necessary for the validation of the technique...
  34. doi request reprint Liver transplantation for the treatment of nodular regenerative hyperplasia
    Tommaso Maria Manzia
    Transplant Unit, Policlinico Tor Vergata, Tor Vergata University, Rome, Italy
    Dig Liver Dis 43:929-34. 2011
    ..The aim of this review was to assess the overall results obtained with liver transplantation and to better define its role in this setting...
  35. ncbi request reprint Complete weaning off immunosuppression in HCV liver transplant recipients is feasible and favourably impacts on the progression of disease recurrence
    Giuseppe Tisone
    Liver Transplant Unit, Surgical Clinic, University of Rome Tor Vergata, S Eugenio Hospital, Viale dell Umanesimo 10, 00144, Rome, Italy
    J Hepatol 44:702-9. 2006
    ..HCV-related disease recurrence progresses rapidly after liver transplantation. We hypothesised that withdrawal of immunosuppression might favourably impact on disease progression...
  36. ncbi request reprint Patterns of chronic hepatitis B in Central Italy: a cross-sectional study
    Paola Piccolo
    Hepatology Unit, University of Rome Tor Vergata, Rome, Italy
    Eur J Public Health 20:711-3. 2010
    ..Therefore, as immigration from non-EU countries continues to grow, we can expect a change in the landscape of HBV-related disease in our area...
  37. doi request reprint A Bayesian methodology to improve prediction of early graft loss after liver transplantation derived from the Liver Match study
    Mario Angelico
    Liver Unit, Tor Vergata University, Rome, Italy Italian Association for the Study of the Liver AISF, Italian National Transplant Centre CNT and Italian Liver Transplant Centres, Italy
    Dig Liver Dis 46:340-7. 2014
    ....
  38. pmc HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors
    Valeria Cento
    Department of Experimental Medicine and Biochemical Sciences, University of Tor Vergata, Rome, Italy
    PLoS ONE 7:e39652. 2012
    ..Because of the extreme genetic variability of hepatitis C virus (HCV), we analyzed whether specific HCV-genotypes are differently prone to develop resistance to linear and macrocyclic protease-inhibitors (PIs)...
  39. ncbi request reprint Lamivudine-resistance mutations can be selected even at very low levels of hepatitis B viraemia
    Valentina Svicher
    University of Rome Tor Vergata, Italy
    Dig Liver Dis 42:902-7. 2010
    ..To investigate lamivudine (LAM)-resistance profiles of hepatitis B virus (HBV) at the early stages of virological breakthrough (serum HBV-DNA 12-345IU/ml) or when HBV-DNA is undetectable...
  40. ncbi request reprint Primary yolk sac tumor of the liver: incidental finding in a patient transplanted for hepatocellular carcinoma
    Ilaria Lenci
    Department of Internal Medicine, Liver Transplant Centre, Tor Vergata University, Rome, Italy
    Transpl Int 21:598-601. 2008
    ..The first 12 months of postoperative follow-up were excellent, with no evidence of tumor recurrence...
  41. ncbi request reprint Interferon-alpha treatment of hepatitis D induces tuberculosis exacerbation in an immigrant
    Claudia Telesca
    Hepatology Unit, Department of Internal Medicine, University of Rome Tor Vergata, Edificio F, Torre Nord, Stanza F 575, Via Montpellier 1, 00133 Rome, Italy
    J Infect 54:e223-6. 2007
    ..We propose that IFN-induced weight loss and anorexia may have played an important role in promoting clinical manifestations of tuberculosis in our patient...
  42. doi request reprint Clinical trial: low plasma cholesterol and oxidative stress predict rapid virological response to standard therapy with peginterferon and ribavirin in HCV patients
    F Angelico
    Department of Experimental Medicine, Division of Internal Medicine C, Sapienza University, Rome, Italy
    Aliment Pharmacol Ther 30:444-51. 2009
    ..Rapid virological response (RVR) is the best predictor of sustained response to standard HCV treatment...
  43. doi request reprint A simple rule to personalize standard dual therapy across all genotypes in naive chronic hepatitis C patients: the TT4 randomized trial
    Simona Francioso
    Hepatology and Liver Transplantation Unit, Department of Experimental Medicine and Surgery, Tor Vergata University, Rome, Italy Electronic address
    Dig Liver Dis 46:164-9. 2014
    ..We aimed at finding a simple rule to determine the shortest duration of dual therapy for all HCV genotypes, obtained by multiplying time to Initial Viral Response, IVR (first undetectable HCV-RNA) by 4 (Tailored Therapy-4, or TT4)...
  44. ncbi request reprint Evaluation of the severity of chronic hepatitis C with 3-T1H-MR spectroscopy
    Antonio Orlacchio
    Department of Diagnostic Imaging, Molecular Imaging, Interventional Radiology, and Radiation Therapy, University Hospital Tor Vergata, Viale Oxford, 81, 00133 Rome, Italy
    AJR Am J Roentgenol 190:1331-9. 2008
    ....
  45. ncbi request reprint Percutaneous cryoablation of small hepatocellular carcinoma with US guidance and CT monitoring: initial experience
    Antonio Orlacchio
    Department of Diagnostic Imaging and Interventional Radiology, University Hospital Tor Vergata, Via Oxford 81, 00199 Rome, Italy
    Cardiovasc Intervent Radiol 31:587-94. 2008
    ..Longer follow-up should provide proof of the effectiveness of this technique...
  46. pmc Ribavirin increases mitogen- and antigen-induced expression of CD40L on CD4+ T cells in vivo
    A Bergamini
    Department of Public Health and Cellular Biology, Chair of Infectious Diseases, University of Rome Tor Vergata, Rome, Italy
    Clin Exp Immunol 130:293-9. 2002
    ....
  47. ncbi request reprint Correlation between liver fibrosis and inflammation in patients transplanted for HCV liver disease
    L Baiocchi
    Hepatology Unit, Department of Internal Medicine, University of Rome Tor Vergata, Rome, Italy
    Am J Transplant 8:673-8. 2008
    ....
  48. ncbi request reprint Recurrent myocardial ischaemia during combination antiviral therapy in a patient with chronic hepatitis C and normal aminotransferase levels
    I Lenci
    Hepatology Unit, Tor Vergata University, Rome, Italy
    Dig Liver Dis 40:785-90. 2008
    ..This case indicates the need of strict electrocardiographic monitoring in elderly patients undergoing treatment with peginterferon and ribavirin...
  49. ncbi request reprint Protective role of tauroursodeoxycholate during harvesting and cold storage of human liver: a pilot study in transplant recipients
    L Falasca
    Department of Surgery, University of Rome Tor Vergata, Italy
    Transplantation 71:1268-76. 2001
    ..CONCLUSIONS: The use of TUDCA during harvesting and cold storage of human liver is associated with significant protection from ischemia-reperfusion injury. The clinical significance of this findings must be studied...
  50. ncbi request reprint Portal vein thrombosis after radiofrequency ablation of HCC
    A Orlacchio
    Department of Diagnostic Imaging and Interventional Radiology, Tor Vergata University Hospital, Rome, Italy
    Minerva Gastroenterol Dietol 56:87-91. 2010
    ..The interest of this case report is due to the fact that portal vein thrombosis did not occur immediately after the procedure, it happened without direct vessel injury by the needle and involved a vessel greater than 3 mm...
  51. pmc Treatment with ribavirin and interferon-alpha reduces interferon-gamma expression in patients with chronic hepatitis C
    A Bergamini
    Department of Public Health, University of Rome Tor Vergata Rome, Italy
    Clin Exp Immunol 123:459-64. 2001
    ..In addition, our findings suggest that ribavirin may exert an anti-inflammatory effect and may help reducing IFN-gamma-driven T cell activation and liver damage...
  52. doi request reprint In vivo, high-field, 3-Tesla 1H MR spectroscopic assessment of liver fibrosis in HCV-correlated chronic liver disease
    A Orlacchio
    Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Policlinico Universitario Tor Vergata, Viale Oxford 81, Rome, Italy
    Radiol Med 113:289-99. 2008
    ..The aim of this study was to correlate the in vivo high-field (3-Tesla) (1)H MRS features of noncirrhotic chronic hepatitis C patients stratified according to the histopathological stages of fibrosis...
  53. pmc Lack of evidence for the Th2 predominance in patients with chronic hepatitis C
    A Bergamini
    Department of Public Health and Cellular Biology, University of Rome Tor Vergata, Rome, Italy
    Clin Exp Immunol 123:451-8. 2001
    ..Finally, no Th2 shift was found in lipopolysaccharide-stimulated monocytes. These data indicate that a Th1 to Th2 shift does not occur in chronic hepatitis C...
  54. ncbi request reprint Liver transplantation in the presence of portal vein thrombosis: report from a single center
    G Orlando
    Surgical Clinic, Tor Vergata University of Rome S Eugenio Hospital, Rome, Italy
    Transplant Proc 36:199-202. 2004
    ..When extensive perivenous and venous inflammatory changes reach the infrapancreatic region, liver transplantation probably should not be performed due to the high mortality rate...
  55. ncbi request reprint A survey on mortality from non-variceal upper gastrointestinal bleeding: Is the emergency referral system adequate?
    Paola Cesaro
    Policlinico Universitario Agostino Gemelli, Rome, Italy
    Dig Liver Dis 45:953-6. 2013
    ....
  56. doi request reprint Liver contrast enhanced ultrasound perfusion imaging in the evaluation of chronic hepatitis C fibrosis: preliminary results
    Antonio Orlacchio
    Department of Diagnostic Imaging Molecular Imaging Interventional Radiology, and Radiation Therapy, University Hospital Tor Vergata, Rome, Italy
    Ultrasound Med Biol 37:1-6. 2011
    ..However, further large-scale studies are required to accurately assess its accuracy in the evaluation of liver fibrosis...
  57. ncbi request reprint Effects of isosorbide-5-mononitrate compared with propranolol on first bleeding and long-term survival in cirrhosis
    M Angelico
    Cattedra di Gastroenterologia, Universita di Roma Tor Vergata, Rome, Italy
    Gastroenterology 113:1632-9. 1997
    ..The aim of this study was to determine the long-term effects of Is-5-Mn vs. propranolol (Pro) on first bleeding, complications, and death in cirrhosis...
  58. ncbi request reprint 13C-methacetin breath test for monitoring hepatic function in cirrhotic patients before and after liver transplantation
    A Petrolati
    Gastroenterology Unit, Department of Public Health, University of Rome Tor Vergata Medical School, Rome, Italy
    Aliment Pharmacol Ther 18:785-90. 2003
    ..The 13C-methacetin breath test is a simple, non-invasive diagnostic tool based on an inexpensive, non-toxic substance, which allows the accurate measurement of liver functional reserve...
  59. ncbi request reprint Extended HBV vaccination in liver transplant recipients for HBV-related cirrhosis: report of two successful cases
    D Di Paolo
    Gastroenterology Unit, Department of Public Health, University of Rome Tor Vergata Medical School, Via Montpellier 1, 00133 Rome, Italy
    Dig Liver Dis 37:793-8. 2005
    ..Conclusion. Extended HBV vaccination may afford valid protection against HBV recurrence in selected liver transplant recipients...
  60. ncbi request reprint Liver transplantation for hepatitis B and C virus-related cirrhosis: mid-term results
    T M Manzia
    Transplant Unit, Department of Surgery, University of Rome Tor Vergata, Rome, Italy
    Transplant Proc 42:1200-3. 2010
    ..Patients transplanted for HBV-HCV coinfection showed a lower fibrosis progression rate compared with HCV monoinfected subjects...
  61. ncbi request reprint Interposition of the right colic angle between the liver and thoracic wall: an unusual cause of massive rectal bleeding following percutaneous biopsy in a liver transplant recipient
    G Orlando
    Liver Transplant Unit, Tor Vergata University of Rome, Surgical Clinic, S Eugenio Hospital, Rome, Italy
    Transplant Proc 37:2629-31. 2005
    ..The latter is the safest and most reliable technique, given the low risk of puncture of other organs and the low probability of obtaining an inadequate sample...
  62. ncbi request reprint Prevalence, incidence and correlates of HHV-8/KSHV infection and Kaposi's sarcoma in renal and liver transplant recipients
    M Andreoni
    Infectious Disease Clinic, Tor Vergata University, S. Eugenio Hospital, Rome, Italy
    J Infect 43:195-9. 2001
    ..However, renal transplant recipients tend to have a higher risk of KS. HHV-8/KSHV reactivation appears to play a greater role on the risk of KS than incident infections...
  63. ncbi request reprint Liver transplantation in Italy: current status. Study Group on Liver Transplantation of the Italian Association for the Study of the Liver (A.I.S.F.)
    P Burra
    Chair of Gastroenterology, University of Padua, Italy
    Dig Liver Dis 32:249-56. 2000
    ..The multidisciplinary Study Group on Liver Transplantation of the Italian Association for the Study of the Liver (AISF) has collected information from all the Italian centres to ascertain the degree of consistency in their methods...
  64. ncbi request reprint Different levels of variability in subtypes 1b and 4a of hepatitis C viruses
    C Argentini
    Laboratory of Virology, Unit of Hepatitis Viruses, University of Rome Tor Vergata, Rome, Italy
    J Biol Regul Homeost Agents 17:147-52. 2003
    ..The phenic analysis also indicated different and complex patterns of amino-acid substitution. Finally, diverse isoelectric points and hydrophobicity were predicted for the two genotypes, with a higher acidity for genotype 4a E1 proteins...
  65. ncbi request reprint Extended double-dosage HBV vaccination after liver transplantation is ineffective, in the absence of lamivudine and prior wash-out of human Hepatitis B immunoglobulins
    D Di Paolo
    Gastroenterology Unit, Department of Public Health, University of Rome Tor Vergata, Medical School, Via Montpellier 1 00133 Rome, Italy
    Dig Liver Dis 38:749-54. 2006
    ..Concomitant lamivudine treatment and the achievement of complete washout of anti-hepatitis B-specific immunoglobulin prior to vaccination in our study could explain the contradiction...
  66. ncbi request reprint Donor liver steatosis and graft selection for liver transplantation: a short review
    M Angelico
    Cattedra di Gastroenterologia, Dipartimento di Sanita Pubblica, Tor Vergata University, Rome, Italy
    Eur Rev Med Pharmacol Sci 9:295-7. 2005
    ..In the transplant setting a precise assessment of steatosis is the prominent reason for performing a liver biopsy of the donor liver...
  67. ncbi request reprint Molecular characterisation of SENV and TTV infections in hepatopathic liver-transplant patients. Brief Report
    D Genovese
    Laboratory of Virology, Istituto Superiore di Sanita, Rome, Italy
    Arch Virol 149:1423-33. 2004
    ..Biological differences seem to exist among different genotypes in terms of viral replication and their persistence...
  68. ncbi request reprint Recurrence of insulin resistant metabolic syndrome following liver transplantation
    Francesco Angelico
    Department of Clinical and Applied Medical Therapy, University of Rome La Sapienza, Italy
    Eur J Gastroenterol Hepatol 15:99-102. 2003
    ..We also stress the need for careful management of the metabolic syndrome in order to decrease the long-term risk for cardiovascular disease...
  69. ncbi request reprint Operational tolerance in clinical liver transplantation: emerging developments
    Giuseppe Tisone
    Transpl Immunol 17:108-13. 2007
    ....
  70. ncbi request reprint Activation of the IGF1 system characterizes cholangiocyte survival during progression of primary biliary cirrhosis
    Paolo Onori
    Department of Experimental Medicine, University of L Aquila, Italy
    J Histochem Cytochem 55:327-34. 2007
    ..This was associated and correlated with a balance of pro- and antiapoptotic proteins favoring survival rather than apoptosis, suggesting a major role of IGF1 system in promoting cholangiocyte survival...
  71. ncbi request reprint Switch to 1.5 grams MMF monotherapy for CNI-related toxicity in liver transplantation is safe and improves renal function, dyslipidemia, and hypertension
    Giuseppe Orlando
    Transplant and General Surgery Unit, S Eugenio Hospital, Italy
    Liver Transpl 13:46-54. 2007
    ..No deaths or major toxicity requiring MMF discontinuation occurred. In conclusion, low dose MMF monotherapy is safe, effective, and well tolerated...
  72. ncbi request reprint Taurohyodeoxycholate- and tauroursodeoxycholate-induced hypercholeresis is augmented in bile duct ligated rats
    Leonardo Baiocchi
    The Texas A and M University System Health Science Center, College of Medicine, Temple, TX 76504, USA
    J Hepatol 38:136-47. 2003
    ..The aim of this study is to determine if the hypercholeretic effect of tauroursodeoxycholate or taurohyodeoxycholate in normal and bile duct ligated (BDL) rats is due to increased ductal secretion...
  73. ncbi request reprint Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha
    Gianfranco Alpini
    Department of Internal Medicine, Scott and White Hospital and The Texas A and M University System Health Science Center, College of Medicine and Central Texas Veterans Health Care System, Temple, TX 76504, USA
    Hepatology 35:1041-52. 2002
    ..Reduced cholangiocyte ABAT may decrease endogenous BA stimulation of cholangiocyte growth and secretion...