P Angeli

Summary

Affiliation: University of Padova
Country: Italy

Publications

  1. ncbi request reprint Cavoportal hemitransposition: a successful way to overcome the problem of total portosplenomesenteric thrombosis in liver transplantation
    Giorgio E Gerunda
    Department of Medical and Surgical Sciences, III Surgical Clinic, Padua University, Padua, Italy
    Liver Transpl 8:72-5. 2002
  2. ncbi request reprint Hyponatremia in cirrhosis: Results of a patient population survey
    Paolo Angeli
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Hepatology 44:1535-42. 2006
  3. doi request reprint Current limits and future challenges in the management of renal dysfunction in patients with cirrhosis: report from the International Club of Ascites
    Paolo Angeli
    Department of Medicine, Unit of Hepatic Emergencies and Liver Transplantation, University of Padova, Padova, Italy
    Liver Int 33:16-23. 2013
  4. doi request reprint Hepatorenal syndrome, MELD score and liver transplantation: an evolving issue with relevant implications for clinical practice
    Paolo Angeli
    Department of Medicine, Unit of Hepatic Emergencies and Liver Transplantation, University of Padova, Italy
    J Hepatol 57:1135-40. 2012
  5. ncbi request reprint The role of nitric oxide in the pathogenesis of systemic and splanchnic vasodilation in cirrhotic rats before and after the onset of ascites
    Paolo Angeli
    Department of Clinical and Experimental Medicine, University of Padua, Via Giustiniani 2, Padova 35100, Italy
    Liver Int 25:429-37. 2005
  6. ncbi request reprint Nephrotoxicity of intravenous immunoglobulin in the setting of liver transplantation or HBV-related cirrhosis: an undervalued topic
    P Angeli
    Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    Minerva Gastroenterol Dietol 54:259-75. 2008
  7. ncbi request reprint Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost
    P Angeli
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Aliment Pharmacol Ther 23:75-84. 2006
  8. ncbi request reprint [The effectiveness of human albumin in liver failure]
    P Angeli
    Dipartimento di Medicina Clinica e Sperimentale, Universita degli Studi di Padova, Padova
    Minerva Anestesiol 71:17-26. 2005
  9. doi request reprint Combined versus sequential diuretic treatment of ascites in non-azotaemic patients with cirrhosis: results of an open randomised clinical trial
    P Angeli
    Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padova, Italy
    Gut 59:98-104. 2010
  10. doi request reprint Hepatorenal syndrome
    Paolo Angeli
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Contrib Nephrol 174:46-55. 2011

Collaborators

Detail Information

Publications50

  1. ncbi request reprint Cavoportal hemitransposition: a successful way to overcome the problem of total portosplenomesenteric thrombosis in liver transplantation
    Giorgio E Gerunda
    Department of Medical and Surgical Sciences, III Surgical Clinic, Padua University, Padua, Italy
    Liver Transpl 8:72-5. 2002
    ..Diffuse PVT no longer appears to be an absolute contraindication to OLT, although cavoportal hemitransposition needs further experience and long-term follow-up...
  2. ncbi request reprint Hyponatremia in cirrhosis: Results of a patient population survey
    Paolo Angeli
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Hepatology 44:1535-42. 2006
    ..In conclusion, low serum sodium levels in cirrhosis are associated with severe ascites and high frequency of hepatic encephalopathy, spontaneous bacterial peritonitis, and hepatorenal syndrome...
  3. doi request reprint Current limits and future challenges in the management of renal dysfunction in patients with cirrhosis: report from the International Club of Ascites
    Paolo Angeli
    Department of Medicine, Unit of Hepatic Emergencies and Liver Transplantation, University of Padova, Padova, Italy
    Liver Int 33:16-23. 2013
    ..It reviews critically our current knowledge and it outlines future perspectives, on the management of renal dysfunction in patients with cirrhosis...
  4. doi request reprint Hepatorenal syndrome, MELD score and liver transplantation: an evolving issue with relevant implications for clinical practice
    Paolo Angeli
    Department of Medicine, Unit of Hepatic Emergencies and Liver Transplantation, University of Padova, Italy
    J Hepatol 57:1135-40. 2012
    ..Finally, the review discusses the appropriate use of combined liver-kidney transplantation (CLKT) in patients with HRS who do not respond to treatment with terlipressin and albumin...
  5. ncbi request reprint The role of nitric oxide in the pathogenesis of systemic and splanchnic vasodilation in cirrhotic rats before and after the onset of ascites
    Paolo Angeli
    Department of Clinical and Experimental Medicine, University of Padua, Via Giustiniani 2, Padova 35100, Italy
    Liver Int 25:429-37. 2005
    ..The role of nitric oxide (NO) in the pathogenesis of splanchnic arterial vasodilation in cirrhosis has been recently debated by some experimental studies...
  6. ncbi request reprint Nephrotoxicity of intravenous immunoglobulin in the setting of liver transplantation or HBV-related cirrhosis: an undervalued topic
    P Angeli
    Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    Minerva Gastroenterol Dietol 54:259-75. 2008
    ..Nevertheless, the inappropriate use of HBIg could increase the risk of renal dysfunction, particularly in combination with nephrotoxic drugs...
  7. ncbi request reprint Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost
    P Angeli
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Aliment Pharmacol Ther 23:75-84. 2006
    ..Intravenous administration of a third-generation cephalosporin is optimal antibiotic treatment for spontaneous bacterial peritonitis...
  8. ncbi request reprint [The effectiveness of human albumin in liver failure]
    P Angeli
    Dipartimento di Medicina Clinica e Sperimentale, Universita degli Studi di Padova, Padova
    Minerva Anestesiol 71:17-26. 2005
  9. doi request reprint Combined versus sequential diuretic treatment of ascites in non-azotaemic patients with cirrhosis: results of an open randomised clinical trial
    P Angeli
    Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padova, Italy
    Gut 59:98-104. 2010
    ..The aim of the study was to compare sequential versus combined diuretic therapy in patients with cirrhosis, moderate ascites and without renal failure...
  10. doi request reprint Hepatorenal syndrome
    Paolo Angeli
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Contrib Nephrol 174:46-55. 2011
    ..Thus, while the optimization of this treatment should be investigated, other therapeutic options should be developed and tested as well...
  11. ncbi request reprint Review article: prognosis of hepatorenal syndrome--has it changed with current practice?
    P Angeli
    Department of Clinical and Experimental Medicine, University of Padua, Italy
    Aliment Pharmacol Ther 20:44-6; discussion 47-8. 2004
    ..Given the shortage of donors for LT, vasoconstrictor therapy and TIPS strategies may be considered as a bridge to LT in patients with type 1 HRS...
  12. ncbi request reprint Reversal of type 1 hepatorenal syndrome with the administration of midodrine and octreotide
    P Angeli
    Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy
    Hepatology 29:1690-7. 1999
    ..Only one patient recovered renal function and underwent liver transplantation. In conclusion, the long-term administration of midodrine and octreotide seems to be an effective and safe treatment of type 1 HRS in patients with cirrhosis...
  13. doi request reprint Donor-Model for End-Stage Liver Disease and donor-recipient matching in liver transplantation
    A Vitale
    Unità di Chirurgia Epatobiliare e Trapianto Epatico, Azienda Università di Padova, Padova, Italy
    Transplant Proc 43:974-6. 2011
    ..The aim of this study was to evaluate the prognostic ability of D-MELD among a cohort of Italian patients already selected for LT on the basis of a D-R matching philosophy...
  14. doi request reprint Estimation of the harm to the waiting list as a crucial factor in the selection of patients with hepatocellular carcinoma for liver transplantation
    A Vitale
    Unità di Chirurgia Epatobiliare e Trapianto Epatico, Azienda Università di Padova, Padova, Italy
    Transplant Proc 42:1194-6. 2010
    ..The aim of this study was to evaluate the minimum post-OLT survival threshold that would justify the selection of a patient with HCC for OLT...
  15. pmc Haeme oxygenase mediates hyporeactivity to phenylephrine in the mesenteric vessels of cirrhotic rats with ascites
    M Bolognesi
    Clinica Medica 5, Dipartimento di Medicina Clinica e Sperimentale, Policlinico Universitario, Via Giustiniani 2, 35128 Padova, Italy
    Gut 54:1630-6. 2005
    ..The aim of this study was to verify the role of haeme oxygenase in the hyporesponsiveness to phenylephrine of small mesenteric arteries in rats with CCl(4) induced cirrhosis, with and without ascites...
  16. doi request reprint Electroencephalographic analysis for the assessment of hepatic encephalopathy: comparison of non-parametric and parametric spectral estimation techniques
    P Amodio
    Clinical Medicine 5, University of Padova, Padova, Italy
    Neurophysiol Clin 39:107-15. 2009
    ..To compare electroencephalographic spectral analysis obtained by periodogram (calculated by means of Fast Fourier Transform) and autoregressive (AR) modelling for the assessment of hepatic encephalopathy...
  17. ncbi request reprint Clinical features and survivial of cirrhotic patients with subclinical cognitive alterations detected by the number connection test and computerized psychometric tests
    P Amodio
    Clinica Medica V, Department of Clinical and Experimental Medicine, University of Padova, Italy
    Hepatology 29:1662-7. 1999
    ..1-5.3), or altered Choice2 test (hazard ratio = 2.8; CI95% = 1.2-6. 3). Multivariate regression showed that Scan and Choice2 tests had prognostic value on survival, in addition to Child-Pugh classes in the first year of follow-up...
  18. doi request reprint A patients' and caregivers' perspective on hepatic encephalopathy
    S Montagnese
    Department of Medicine, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy
    Metab Brain Dis 27:567-72. 2012
    ..In conclusion, HE awareness was poor in both patients and caregivers, most likely in relation to insufficient/inadequate provision of information...
  19. doi request reprint Microwave thermal ablation for hepatocarcinoma: six liver transplantation cases
    G Zanus
    General Surgery and Organ Transplantation, Hepatobiliary Surgery and Liver Transplant Unit, Azienda Università di Padova, Padova, Italy
    Transplant Proc 43:1091-4. 2011
    ..In conclusion, a MWA seemed to be a safe novel approach to treat HCC and could serve as a "bridge" to OLT and down-staging for patients with HCC...
  20. ncbi request reprint Randomized clinical study of the efficacy of amiloride and potassium canrenoate in nonazotemic cirrhotic patients with ascites
    P Angeli
    Department of Clinical Medicine, University of Padua, Italy
    Hepatology 19:72-9. 1994
    ..abstract truncated at 250 words)..
  21. ncbi request reprint Increased activity of guanosine 3'-5'-cyclic monophosphate phosphodiesterase in the renal tissue of cirrhotic rats with ascites
    P Angeli
    Department of Clinical and Experimental Medicine, University of Padua, Italy
    Hepatology 31:304-10. 2000
    ..HS-142-1 prevented any renal effect of Zaprinast in cirrhotic rats. In conclusion, an increased activity of the cGMP-PDE in renal tissue contributes to the renal resistance to ENP in cirrhosis with ascites...
  22. ncbi request reprint Prevalence and prognostic value of quantified electroencephalogram (EEG) alterations in cirrhotic patients
    P Amodio
    Clinical Medicine 5th, University of Padova, Italy
    J Hepatol 35:37-45. 2001
    ..We, therefore, performed a study to ascertain the features and the prognosis of cirrhotic patients without current overt hepatic encephalopathy (OHE) who have EEG alterations...
  23. ncbi request reprint Neurological complications after orthotopic liver transplantation
    P Amodio
    Clinical Medicine 5 and Veneto Regional Reference Centre for Hepatic Diseases, University of Padova, Padova, Italy
    Dig Liver Dis 39:740-7. 2007
    ..The number of orthotopic liver transplantation performed each year is increasing due to increased safety and logistic facilities. Therefore, the importance of reducing adverse events is progressively growing...
  24. ncbi request reprint Alcohol- and substance-dependent subjects: the correlated factors in qualifying for liver transplantation
    L Gallimberti
    Toxicological Clinic of Addictions, General Hospital, University of Padua, Padua, Italy
    Transplant Proc 39:1861-3. 2007
    ..To identify the most significant variables in determining if candidates with past or current addictions can be considered for liver transplantation...
  25. ncbi request reprint Comparison between nifedipine and carvedilol in the treatment of de novo arterial hypertension after liver transplantation: preliminary results of a controlled clinical trial
    A Galioto
    Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy
    Transplant Proc 37:1245-7. 2005
    ..Two of the nine nonresponders to nifedipine responded to carvedilol. The efficacy of monotherapy was observed in 11 of 40 randomized patients (27.5%). Carvedilol monotherapy is as effective as nifedipine but far better tolerated...
  26. doi request reprint Use of sorafenib in patients with hepatocellular carcinoma before liver transplantation: a cost-benefit analysis while awaiting data on sorafenib safety
    Alessandro Vitale
    Unità di Chirurgia Oncologica, Istituto Oncologico Veneto, IRCCS, Padova, Italy
    Hepatology 51:165-73. 2010
    ....
  27. ncbi request reprint Change in portal flow after liver transplantation: effect on hepatic arterial resistance indices and role of spleen size
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, Institute of General Surgery, Intensive Care Unit, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
    Hepatology 35:601-8. 2002
    ..A normal time course of portal-hepatic hemodynamics was detected in patients transplanted for acute liver failure...
  28. doi request reprint Response to therapy as a criterion for awarding priority to patients with hepatocellular carcinoma awaiting liver transplantation
    Alessandro Vitale
    Unità di Chirurgia Oncologica, Istituto Oncologico Veneto, IRCCS, Padova, Italy
    Ann Surg Oncol 17:2290-302. 2010
    ..This study was designed to assess the effectiveness of a policy for prioritizing HCC patients according to their response to pre-LT therapy...
  29. doi request reprint The survival benefit of liver transplantation in hepatocellular carcinoma patients
    Umberto Cillo
    Unità di Chirurgia Epatobiliare e Trapianto Epatico, Azienda Ospedaliera Universita di Padova, Via Giustiniani 2, 35128 Padova, Italy
    Dig Liver Dis 42:642-9. 2010
    ..There are no studies evaluating the survival benefit of liver transplantation over alternative therapies for patients with hepatocellular carcinoma...
  30. doi request reprint Improving the inhibitory control task to detect minimal hepatic encephalopathy
    Piero Amodio
    Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
    Gastroenterology 139:510-8, 518.e1-2. 2010
    ..We assessed the efficacy of ICT compared with recommended diagnostic standards...
  31. ncbi request reprint Acute liver rejection: accuracy and predictive values of doppler US measurements--initial experience
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, Institute of General Surgery, Clinica Medica 5, Policlinico Universitario, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
    Radiology 235:651-8. 2005
    ....
  32. doi request reprint Detection of minimal hepatic encephalopathy: normalization and optimization of the Psychometric Hepatic Encephalopathy Score. A neuropsychological and quantified EEG study
    Piero Amodio
    Department of Clinical and Experimental Medicine, CIRMANMEC, University of Padua, Via Giustiniani, 2, 35128 Padua, Italy
    J Hepatol 49:346-53. 2008
    ..We aimed at standardizing PHES in Italy and comparing Italian, German and Spanish norms in EEG characterized cirrhotic patients...
  33. ncbi request reprint A placebo-controlled clinical trial of nadolol in the prophylaxis of growth of small esophageal varices in cirrhosis
    Carlo Merkel
    Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy
    Gastroenterology 127:476-84. 2004
    ..Beta-blockers are extensively used to prevent variceal bleeding in patients with large esophageal varices. It is not established if beta-blockers delay the growth of small varices...
  34. ncbi request reprint Renal failure and bacterial infections in patients with cirrhosis: epidemiology and clinical features
    Silvano Fasolato
    Department of Clinical and Experimental Medicine, General Hospital and University of Padova, Padova, Italy
    Hepatology 45:223-9. 2007
    ..A progressive form of renal failure occurs only as a consequence of biliary or gastrointestinal tract infections, SBP, and UTI...
  35. ncbi request reprint Carbon monoxide-mediated activation of large-conductance calcium-activated potassium channels contributes to mesenteric vasodilatation in cirrhotic rats
    Massimo Bolognesi
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    J Pharmacol Exp Ther 321:187-94. 2007
    ....
  36. ncbi request reprint Bacterial infection in patients with advanced cirrhosis: a multicentre prospective study
    M Borzio
    Department of Medicine, Fatebenefratelli Hospital, Milan, Italy
    Dig Liver Dis 33:41-8. 2001
    ..To evaluate the prevalence, incidence and clinical relevance of bacterial infection in predominantly non-alcoholic cirrhotic patients hospitalised for decompensation...
  37. doi request reprint The liver: another organ involved in Muir Torre syndrome?
    F Morando
    Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128, Padova, Italy
    Fam Cancer 11:7-12. 2012
    ..Here, we describe a case of Muir Torre syndrome associated with an hepatocellular-carcinoma in a patient with a non-cirrhotic liver and an HNPCC-family with multiple cases of hepatocellular carcinoma...
  38. doi request reprint Prospective validation of a new priority allocation model for liver transplant candidates: an interim analysis
    A Vitale
    Unità di Chirurgia Epatobiliare e Trapianto Epatico, Dipartimento di Chirurgia Generale e Trapianti d Organo, Azienda Ospedaliera Universita di Padova, Padova, Italy
    Transplant Proc 41:1092-5. 2009
    ..We sought to prospectively validate a priority allocation model that is believed to achieve objectivity without penalizing dropout risk and post-OLT results...
  39. ncbi request reprint P300 latency for the diagnosis of minimal hepatic encephalopathy: evidence that spectral EEG analysis and psychometric tests are enough
    P Amodio
    Department of Clinical Medicine 5, Via Giustiniani, 2, University of Padova, Padova 35128, Italy
    Dig Liver Dis 37:861-8. 2005
    ..Event-related evoked potentials (P300 latency) were proposed as the best tool to assess this condition. EEG spectral analysis and psychometric evaluation are also used to assess minimal hepatic encephalopathy...
  40. doi request reprint Prognostic evaluation of the donor risk index among a prospective cohort of Italian patients undergoing liver transplantation
    A Vitale
    Unità di Chirurgia Oncologica, Istituto Oncologico Veneto, IRCCS, Padova, Italy
    Transplant Proc 41:1096-8. 2009
    ..The aim of this study was to prospectively evaluate the prognostic ability of DRI among a cohort of Italian patients undergoing OLT...
  41. ncbi request reprint Comparison between two high-dose methylprednisolone schedules in the treatment of acute hepatic cellular rejection in liver transplant recipients: a controlled clinical trial
    Roberta Volpin
    Department of Clinical and Experimental Medicine, University of Padua, Italy
    Liver Transpl 8:527-34. 2002
    ....
  42. ncbi request reprint Arteroportal fistulas between the accessory right hepatic, gastroduodenal and superior mesenteric arteries and portal vein: a difficult technical problem to overcome in liver transplantation
    Giorgio E Gerunda
    Department of Surgical and Medical Sciences, III Surgical Clinic, Policlinico Universitario, Via Giustiniani 2, 35128 Padova, Italy
    Transplantation 73:417-9. 2002
    ..Fistulous communications between the accessory right hepatic (ARHA), gastroduodenal (GD), and superior mesenteric (SMA) arteries and the portal vein (PV) may represent a contraindication for liver transplantation (LT)...
  43. ncbi request reprint Portal hypertension and portal hypertensive gastropathy in patients with liver cirrhosis: a haemodynamic study
    C Merkel
    Department of Clinical and Experimental Medicine, University of Padua, Via Giustiniani, 2, 35128 Padua, Italy
    Dig Liver Dis 35:269-74. 2003
    ..The relationships between the levels of portal hypertension and the morphologic alterations of gastric mucosa in patients with liver cirrhosis--generally described as portal hypertensive gastropathy--are poorly defined...
  44. doi request reprint An abnormal gene expression of the beta-adrenergic system contributes to the pathogenesis of cardiomyopathy in cirrhotic rats
    Giulio Ceolotto
    Department of Clinical and Experimental Medicine, University of Padova Medical School, Padova, Italy
    Hepatology 48:1913-23. 2008
    ..These results indicate that overexpression of Galpha(i2), PDE2a, and RGS2 down-regulates the beta-adrenergic signaling pathway, thus contributing to the pathogenesis of cirrhotic cardiomyopathy...
  45. doi request reprint Nifedipine versus carvedilol in the treatment of de novo arterial hypertension after liver transplantation: results of a controlled clinical trial
    Alessandra Galioto
    Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
    Liver Transpl 14:1020-8. 2008
    ..In responders to carvedilol, but not in responders to nifedipine, the daily dose of tacrolimus at 1 year should be reduced to 50% compared to the baseline dose to maintain the blood trough level in the therapeutic range...
  46. doi request reprint Pathogenesis and management of hepatorenal syndrome in patients with cirrhosis
    Paolo Angeli
    Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35126 Padova, Italy
    J Hepatol 48:S93-103. 2008
    ..Recent developments in pathophysiology are the basis of the new therapeutic strategies, which are currently under evaluation in randomised clinical trials...
  47. ncbi request reprint Transduction of the liver with activated Akt normalizes portal pressure in cirrhotic rats
    Manuel Morales-Ruiz
    Hormonal Laboratory, Hospital Clnic Universitari, Villarroel 170, Barcelona 08036, Spain
    Gastroenterology 125:522-31. 2003
    ..For this reason the aims of the present study were to determine whether there is an impaired Akt activation in cirrhotic livers and how this phenomenon relates to the decrease in NO production associated with portal hypertension...
  48. doi request reprint Effects of satavaptan, a selective vasopressin V(2) receptor antagonist, on ascites and serum sodium in cirrhosis with hyponatremia: a randomized trial
    Pere Gines
    Hospital Clinic, University of Barcelona, Institut d Investigacions Biomédiques August Pi Sunyer IDIBAPS, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Barcelona, Catalunya, Spain
    Hepatology 48:204-13. 2008
    ..01 for all compared to placebo). Thirst was significantly more common in patients treated with satavaptan compared to those treated with placebo, whereas the frequency of other adverse events was similar among groups...
  49. ncbi request reprint The management of ascites in cirrhosis: report on the consensus conference of the International Ascites Club
    Kevin P Moore
    Centre for Hepatology, Royal Free and University College Medical School, UCL, London, United Kingdom
    Hepatology 38:258-66. 2003
    ..Liver transplantation should be considered for all ascitic patients, and this should preferably be performed prior to the development of renal dysfunction to prevent further compromise of their prognosis...