Research Topics
| P AngeliSummaryAffiliation: University of Padova Country: Italy Publications
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Detail Information
Publications
Cavoportal hemitransposition: a successful way to overcome the problem of total portosplenomesenteric thrombosis in liver transplantationGiorgio E Gerunda
Department of Medical and Surgical Sciences, III Surgical Clinic, Padua University, Padua, Italy
Liver Transpl 8:72-5. 2002..Diffuse PVT no longer appears to be an absolute contraindication to OLT, although cavoportal hemitransposition needs further experience and long-term follow-up...- Hyponatremia in cirrhosis: Results of a patient population surveyPaolo Angeli
Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Hepatology 44:1535-42. 2006..In conclusion, low serum sodium levels in cirrhosis are associated with severe ascites and high frequency of hepatic encephalopathy, spontaneous bacterial peritonitis, and hepatorenal syndrome... 
Current limits and future challenges in the management of renal dysfunction in patients with cirrhosis: report from the International Club of AscitesPaolo Angeli
Department of Medicine, Unit of Hepatic Emergencies and Liver Transplantation, University of Padova, Padova, Italy
Liver Int 33:16-23. 2013..It reviews critically our current knowledge and it outlines future perspectives, on the management of renal dysfunction in patients with cirrhosis...- Hepatorenal syndrome, MELD score and liver transplantation: An evolving issue with relevant implications for clinical practicePaolo Angeli
Department of Medicine, Unit of Hepatic Emergencies and Liver Transplantation, University of Padova, Italy Electronic address
J Hepatol 57:1135-40. 2012..Finally, the review discusses the appropriate use of combined liver-kidney transplantation (CLKT) in patients with HRS who do not respond to treatment with terlipressin and albumin... - Nephrotoxicity of intravenous immunoglobulin in the setting of liver transplantation or HBV-related cirrhosis: an undervalued topicP Angeli
Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
Minerva Gastroenterol Dietol 54:259-75. 2008..Nevertheless, the inappropriate use of HBIg could increase the risk of renal dysfunction, particularly in combination with nephrotoxic drugs... - Combined versus sequential diuretic treatment of ascites in non-azotaemic patients with cirrhosis: results of an open randomised clinical trialP Angeli
Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, Padova, Italy
Gut 59:98-104. 2010..The aim of the study was to compare sequential versus combined diuretic therapy in patients with cirrhosis, moderate ascites and without renal failure... - [The effectiveness of human albumin in liver failure]P Angeli
Dipartimento di Medicina Clinica e Sperimentale, , Padova
Minerva Anestesiol 71:17-26. 2005 - Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower costP Angeli
Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Aliment Pharmacol Ther 23:75-84. 2006..Intravenous administration of a third-generation cephalosporin is optimal antibiotic treatment for spontaneous bacterial peritonitis... - The role of nitric oxide in the pathogenesis of systemic and splanchnic vasodilation in cirrhotic rats before and after the onset of ascitesPaolo Angeli
Department of Clinical and Experimental Medicine, University of Padua, Via Giustiniani 2, Padova 35100, Italy
Liver Int 25:429-37. 2005..The role of nitric oxide (NO) in the pathogenesis of splanchnic arterial vasodilation in cirrhosis has been recently debated by some experimental studies... - Review article: prognosis of hepatorenal syndrome--has it changed with current practice?P Angeli
Department of Clinical and Experimental Medicine, University of Padua, Italy
Aliment Pharmacol Ther 20:44-6; discussion 47-8. 2004..Given the shortage of donors for LT, vasoconstrictor therapy and TIPS strategies may be considered as a bridge to LT in patients with type 1 HRS... - Hepatorenal syndromePaolo Angeli
Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Contrib Nephrol 174:46-55. 2011..Thus, while the optimization of this treatment should be investigated, other therapeutic options should be developed and tested as well... - Reversal of type 1 hepatorenal syndrome with the administration of midodrine and octreotideP Angeli
Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy
Hepatology 29:1690-7. 1999..Only one patient recovered renal function and underwent liver transplantation. In conclusion, the long-term administration of midodrine and octreotide seems to be an effective and safe treatment of type 1 HRS in patients with cirrhosis... - Donor-Model for End-Stage Liver Disease and donor-recipient matching in liver transplantationA Vitale
Unità di Chirurgia Epatobiliare e Trapianto Epatico, Azienda Università di Padova, Padova, Italy
Transplant Proc 43:974-6. 2011..The aim of this study was to evaluate the prognostic ability of D-MELD among a cohort of Italian patients already selected for LT on the basis of a D-R matching philosophy... - Estimation of the harm to the waiting list as a crucial factor in the selection of patients with hepatocellular carcinoma for liver transplantationA Vitale
Unità di Chirurgia Epatobiliare e Trapianto Epatico, Azienda Università di Padova, Padova, Italy
Transplant Proc 42:1194-6. 2010..The aim of this study was to evaluate the minimum post-OLT survival threshold that would justify the selection of a patient with HCC for OLT... 
Haeme oxygenase mediates hyporeactivity to phenylephrine in the mesenteric vessels of cirrhotic rats with ascitesM Bolognesi
Clinica Medica 5, Dipartimento di Medicina Clinica e Sperimentale, Policlinico Universitario, Via Giustiniani 2, 35128 Padova, Italy
Gut 54:1630-6. 2005..The aim of this study was to verify the role of haeme oxygenase in the hyporesponsiveness to phenylephrine of small mesenteric arteries in rats with CCl(4) induced cirrhosis, with and without ascites...- Electroencephalographic analysis for the assessment of hepatic encephalopathy: comparison of non-parametric and parametric spectral estimation techniquesP Amodio
Clinical Medicine 5, University of Padova, Padova, Italy
Neurophysiol Clin 39:107-15. 2009..To compare electroencephalographic spectral analysis obtained by periodogram (calculated by means of Fast Fourier Transform) and autoregressive (AR) modelling for the assessment of hepatic encephalopathy... - Clinical features and survivial of cirrhotic patients with subclinical cognitive alterations detected by the number connection test and computerized psychometric testsP Amodio
Clinica Medica V, Department of Clinical and Experimental Medicine, University of Padova, Italy
Hepatology 29:1662-7. 1999..1-5.3), or altered Choice2 test (hazard ratio = 2.8; CI95% = 1.2-6. 3). Multivariate regression showed that Scan and Choice2 tests had prognostic value on survival, in addition to Child-Pugh classes in the first year of follow-up... - A patients' and caregivers' perspective on hepatic encephalopathyS Montagnese
Department of Medicine, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy
Metab Brain Dis 27:567-72. 2012..In conclusion, HE awareness was poor in both patients and caregivers, most likely in relation to insufficient/inadequate provision of information... - Microwave thermal ablation for hepatocarcinoma: six liver transplantation casesG Zanus
General Surgery and Organ Transplantation, Hepatobiliary Surgery and Liver Transplant Unit, Azienda Università di Padova, Padova, Italy
Transplant Proc 43:1091-4. 2011..In conclusion, a MWA seemed to be a safe novel approach to treat HCC and could serve as a "bridge" to OLT and down-staging for patients with HCC... - Randomized clinical study of the efficacy of amiloride and potassium canrenoate in nonazotemic cirrhotic patients with ascitesP Angeli
Department of Clinical Medicine, University of Padua, Italy
Hepatology 19:72-9. 1994..abstract truncated at 250 words).. - Increased activity of guanosine 3'-5'-cyclic monophosphate phosphodiesterase in the renal tissue of cirrhotic rats with ascitesP Angeli
Department of Clinical and Experimental Medicine, University of Padua, Italy
Hepatology 31:304-10. 2000..HS-142-1 prevented any renal effect of Zaprinast in cirrhotic rats. In conclusion, an increased activity of the cGMP-PDE in renal tissue contributes to the renal resistance to ENP in cirrhosis with ascites... - Prevalence and prognostic value of quantified electroencephalogram (EEG) alterations in cirrhotic patientsP Amodio
Clinical Medicine 5th, University of Padova, Italy
J Hepatol 35:37-45. 2001..We, therefore, performed a study to ascertain the features and the prognosis of cirrhotic patients without current overt hepatic encephalopathy (OHE) who have EEG alterations... - Neurological complications after orthotopic liver transplantationP Amodio
Clinical Medicine 5 and Veneto Regional Reference Centre for Hepatic Diseases, University of Padova, Padova, Italy
Dig Liver Dis 39:740-7. 2007..The number of orthotopic liver transplantation performed each year is increasing due to increased safety and logistic facilities. Therefore, the importance of reducing adverse events is progressively growing... - Comparison between nifedipine and carvedilol in the treatment of de novo arterial hypertension after liver transplantation: preliminary results of a controlled clinical trialA Galioto
Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy
Transplant Proc 37:1245-7. 2005..Two of the nine nonresponders to nifedipine responded to carvedilol. The efficacy of monotherapy was observed in 11 of 40 randomized patients (27.5%). Carvedilol monotherapy is as effective as nifedipine but far better tolerated... - Alcohol- and substance-dependent subjects: the correlated factors in qualifying for liver transplantationL Gallimberti
Toxicological Clinic of Addictions, General Hospital, University of Padua, Padua, Italy
Transplant Proc 39:1861-3. 2007..To identify the most significant variables in determining if candidates with past or current addictions can be considered for liver transplantation... - Improving the inhibitory control task to detect minimal hepatic encephalopathyPiero Amodio
Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy
Gastroenterology 139:510-8, 518.e1-2. 2010..We assessed the efficacy of ICT compared with recommended diagnostic standards... - Use of sorafenib in patients with hepatocellular carcinoma before liver transplantation: a cost-benefit analysis while awaiting data on sorafenib safetyAlessandro Vitale
Unità di Chirurgia Oncologica, Istituto Oncologico Veneto, IRCCS, Padova, Italy
Hepatology 51:165-73. 2010.... - The survival benefit of liver transplantation in hepatocellular carcinoma patientsUmberto Cillo
Unità di Chirurgia Epatobiliare e Trapianto Epatico, Azienda Ospedaliera Universita di Padova, Via Giustiniani 2, 35128 Padova, Italy
Dig Liver Dis 42:642-9. 2010..There are no studies evaluating the survival benefit of liver transplantation over alternative therapies for patients with hepatocellular carcinoma... - Response to therapy as a criterion for awarding priority to patients with hepatocellular carcinoma awaiting liver transplantationAlessandro Vitale
Unità di Chirurgia Oncologica, Istituto Oncologico Veneto, IRCCS, Padova, Italy
Ann Surg Oncol 17:2290-302. 2010..This study was designed to assess the effectiveness of a policy for prioritizing HCC patients according to their response to pre-LT therapy... - Acute liver rejection: accuracy and predictive values of doppler US measurements--initial experienceMassimo Bolognesi
Department of Clinical and Experimental Medicine, Institute of General Surgery, Clinica Medica 5, Policlinico Universitario, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
Radiology 235:651-8. 2005.... - Change in portal flow after liver transplantation: effect on hepatic arterial resistance indices and role of spleen sizeMassimo Bolognesi
Department of Clinical and Experimental Medicine, Institute of General Surgery, Intensive Care Unit, University of Padua, Via Giustiniani 2, 35128 Padua, Italy
Hepatology 35:601-8. 2002..A normal time course of portal-hepatic hemodynamics was detected in patients transplanted for acute liver failure... - A placebo-controlled clinical trial of nadolol in the prophylaxis of growth of small esophageal varices in cirrhosisCarlo Merkel
Department of Clinical and Experimental Medicine, University of Padua, Padova, Italy
Gastroenterology 127:476-84. 2004..Beta-blockers are extensively used to prevent variceal bleeding in patients with large esophageal varices. It is not established if beta-blockers delay the growth of small varices... - Detection of minimal hepatic encephalopathy: normalization and optimization of the Psychometric Hepatic Encephalopathy Score. A neuropsychological and quantified EEG studyPiero Amodio
Department of Clinical and Experimental Medicine, CIRMANMEC, University of Padua, Via Giustiniani, 2, 35128 Padua, Italy
J Hepatol 49:346-53. 2008..We aimed at standardizing PHES in Italy and comparing Italian, German and Spanish norms in EEG characterized cirrhotic patients... - Renal failure and bacterial infections in patients with cirrhosis: epidemiology and clinical featuresSilvano Fasolato
Department of Clinical and Experimental Medicine, General Hospital and University of Padova, Padova, Italy
Hepatology 45:223-9. 2007..A progressive form of renal failure occurs only as a consequence of biliary or gastrointestinal tract infections, SBP, and UTI... - Carbon monoxide-mediated activation of large-conductance calcium-activated potassium channels contributes to mesenteric vasodilatation in cirrhotic ratsMassimo Bolognesi
Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
J Pharmacol Exp Ther 321:187-94. 2007.... - Bacterial infection in patients with advanced cirrhosis: a multicentre prospective studyM Borzio
Department of Medicine, Fatebenefratelli Hospital, Milan, Italy
Dig Liver Dis 33:41-8. 2001..To evaluate the prevalence, incidence and clinical relevance of bacterial infection in predominantly non-alcoholic cirrhotic patients hospitalised for decompensation... - The liver: another organ involved in Muir Torre syndrome?F Morando
Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128, Padova, Italy
Fam Cancer 11:7-12. 2012..Here, we describe a case of Muir Torre syndrome associated with an hepatocellular-carcinoma in a patient with a non-cirrhotic liver and an HNPCC-family with multiple cases of hepatocellular carcinoma... - Prospective validation of a new priority allocation model for liver transplant candidates: an interim analysisA Vitale
Unità di Chirurgia Epatobiliare e Trapianto Epatico, Dipartimento di Chirurgia Generale e Trapianti d Organo, Azienda Ospedaliera Universita di Padova, Padova, Italy
Transplant Proc 41:1092-5. 2009..We sought to prospectively validate a priority allocation model that is believed to achieve objectivity without penalizing dropout risk and post-OLT results... - Prognostic evaluation of the donor risk index among a prospective cohort of Italian patients undergoing liver transplantationA Vitale
Unità di Chirurgia Oncologica, Istituto Oncologico Veneto, IRCCS, Padova, Italy
Transplant Proc 41:1096-8. 2009..The aim of this study was to prospectively evaluate the prognostic ability of DRI among a cohort of Italian patients undergoing OLT... - P300 latency for the diagnosis of minimal hepatic encephalopathy: evidence that spectral EEG analysis and psychometric tests are enoughP Amodio
Department of Clinical Medicine 5, Via Giustiniani, 2, University of Padova, Padova 35128, Italy
Dig Liver Dis 37:861-8. 2005..Event-related evoked potentials (P300 latency) were proposed as the best tool to assess this condition. EEG spectral analysis and psychometric evaluation are also used to assess minimal hepatic encephalopathy... - Arteroportal fistulas between the accessory right hepatic, gastroduodenal and superior mesenteric arteries and portal vein: a difficult technical problem to overcome in liver transplantationGiorgio E Gerunda
Department of Surgical and Medical Sciences, III Surgical Clinic, Policlinico Universitario, Via Giustiniani 2, 35128 Padova, Italy
Transplantation 73:417-9. 2002..CONCLUSIONS: Extrahepatic multiple APF would no longer to represent a contraindication to LT, although this claim needs to be confirmed in the light of further experience and a longer-term follow-up... - Comparison between two high-dose methylprednisolone schedules in the treatment of acute hepatic cellular rejection in liver transplant recipients: a controlled clinical trialRoberta Volpin
Department of Clinical and Experimental Medicine, University of Padua, Italy
Liver Transpl 8:527-34. 2002.... - Portal hypertension and portal hypertensive gastropathy in patients with liver cirrhosis: a haemodynamic studyC Merkel
Department of Clinical and Experimental Medicine, University of Padua, Via Giustiniani, 2, 35128 Padua, Italy
Dig Liver Dis 35:269-74. 2003..The relationships between the levels of portal hypertension and the morphologic alterations of gastric mucosa in patients with liver cirrhosis--generally described as portal hypertensive gastropathy--are poorly defined... - Nifedipine versus carvedilol in the treatment of de novo arterial hypertension after liver transplantation: results of a controlled clinical trialAlessandra Galioto
Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy
Liver Transpl 14:1020-8. 2008..In responders to carvedilol, but not in responders to nifedipine, the daily dose of tacrolimus at 1 year should be reduced to 50% compared to the baseline dose to maintain the blood trough level in the therapeutic range... - An abnormal gene expression of the beta-adrenergic system contributes to the pathogenesis of cardiomyopathy in cirrhotic ratsGiulio Ceolotto
Department of Clinical and Experimental Medicine, University of Padova Medical School, Padova, Italy
Hepatology 48:1913-23. 2008..These results indicate that overexpression of Galpha(i2), PDE2a, and RGS2 down-regulates the beta-adrenergic signaling pathway, thus contributing to the pathogenesis of cirrhotic cardiomyopathy... - Pathogenesis and management of hepatorenal syndrome in patients with cirrhosisPaolo Angeli
Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35126 Padova, Italy
J Hepatol 48:S93-103. 2008..Recent developments in pathophysiology are the basis of the new therapeutic strategies, which are currently under evaluation in randomised clinical trials... - Transduction of the liver with activated Akt normalizes portal pressure in cirrhotic ratsManuel Morales-Ruiz
Hormonal Laboratory, Hospital Clnic Universitari, Villarroel 170, Barcelona 08036, Spain
Gastroenterology 125:522-31. 2003..For this reason the aims of the present study were to determine whether there is an impaired Akt activation in cirrhotic livers and how this phenomenon relates to the decrease in NO production associated with portal hypertension... - Effects of satavaptan, a selective vasopressin V(2) receptor antagonist, on ascites and serum sodium in cirrhosis with hyponatremia: a randomized trialPere Gines
Hospital Clinic, University of Barcelona, Institut d Investigacions Biomédiques August Pi Sunyer IDIBAPS, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Barcelona, Catalunya, Spain
Hepatology 48:204-13. 2008..01 for all compared to placebo). Thirst was significantly more common in patients treated with satavaptan compared to those treated with placebo, whereas the frequency of other adverse events was similar among groups... - The management of ascites in cirrhosis: report on the consensus conference of the International Ascites ClubKevin P Moore
Centre for Hepatology, Royal Free and University College Medical School, UCL, London, United Kingdom
Hepatology 38:258-66. 2003..Liver transplantation should be considered for all ascitic patients, and this should preferably be performed prior to the development of renal dysfunction to prevent further compromise of their prognosis...