Research Topics
| Claudia AndreiniSummaryAffiliation: University of Florence Country: Italy Publications
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Detail Information
Publications
MetalPDB: a database of metal sites in biological macromolecular structuresClaudia Andreini
Magnetic Resonance Center CERM, University of Florence, Via L Sacconi 6, 50019 Sesto, Fiorentino, Italy
Nucleic Acids Res 41:D312-9. 2013..MetalPDB is updated monthly in an automated manner...
FindGeo: a tool for determining metal coordination geometryClaudia Andreini
Magnetic Resonance Center CERM, University of Florence, Via L Sacconi 6, 50019 Sesto Fiorentino, Italy
Bioinformatics 28:1658-60. 2012..AVAILABILITY: FindGeo is freely available as a web service and as a stand-alone program at http://metalweb.cerm.unifi.it/tools/findgeo/...
Predicting zinc binding at the proteome levelAndrea Passerini
Machine Learning and Neural Networks Group, Dipartimento di Sistemi e Informatica, Universita degli Studi di Firenze, Italy
BMC Bioinformatics 8:39. 2007..Metal-binding properties remain difficult to predict as well as to investigate experimentally at the whole-proteome level. Consequently, the current knowledge about metalloproteins is only partial...
Metalloproteomes: a bioinformatic approachClaudia Andreini
Magnetic Resonance Center CERM and Department of Chemistry, University of Florence, Via L Sacconi 6, 50019 Sesto Fiorentino, Italy
Acc Chem Res 42:1471-9. 2009....
Metal-MACiE: a database of metals involved in biological catalysisClaudia Andreini
Magnetic Resonance Center CERM, University of Florence, 50019 Sesto Fiorentino, Italy
Bioinformatics 25:2088-9. 2009..The two databases constitute complementary sources of information for enzymology, biochemistry and molecular pharmacology studies. AVAILABILITY: http://www.ebi.ac.uk/thornton-srv/databases/Metal_MACiE/home.html...
Structural analysis of metal sites in proteins: non-heme iron sites as a case studyClaudia Andreini
Magnetic Resonance Center CERM University of Florence, Via L Sacconi 6, 50019 Sesto Fiorentino, Italy
J Mol Biol 388:356-80. 2009..Structural templates of metal sites, finally, may constitute the basis for a systematic classification of metalloproteins in databases...
Occurrence of copper proteins through the three domains of life: a bioinformatic approachClaudia Andreini
Magnetic Resonance Center CERM and Department of Chemistry, University of Florence, Via L Sacconi 6, 50019 Sesto Fiorentino, Italy
J Proteome Res 7:209-16. 2008..A network involving proteins having roles in both copper transport and respiration was identified, parts or all of which are detected in the majority of the organisms examined...
Non-heme iron through the three domains of lifeClaudia Andreini
Magnetic Resonance Center CERM and Department of Chemistry, University of Florence, 50019 Sesto Fiorentino, Italy
Proteins 67:317-24. 2007..9% +/- 1.6%) and in eukaryota (1.1% +/- 0.4%). The analysis of the function of each putative iron-protein identified suggests that extant organisms have inherited the large majority of their iron-proteome from the last common ancestor...
Metal ions in biological catalysis: from enzyme databases to general principlesClaudia Andreini
Magnetic Resonance Center CERM, University of Florence, Via L Sacconi 6, 50019, Sesto Fiorentino, Italy
J Biol Inorg Chem 13:1205-18. 2008..The control of the reactivity of redox-active metal ions may involve their association with organic cofactors to form stable units. This occurs sometimes for iron and nickel, and quite often for cobalt and molybdenum...
Zinc through the three domains of lifeClaudia Andreini
Magnetic Resonance Center (CERM, University of Florence, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy
J Proteome Res 5:3173-8. 2006..8%) is significantly higher than that observed in Bacteria and Archaea (from 5% to 6%). Most of this enrichment is due to the larger portfolio of regulatory proteins in Eukaryota...
Comparative analysis of the ADAM and ADAMTS familiesClaudia Andreini
Magnetic Resonance Center (CERM, University of Florence, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy
J Proteome Res 4:881-8. 2005....
Counting the zinc-proteins encoded in the human genomeClaudia Andreini
Magnetic Resonance Center (CERM, University of Florence, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy
J Proteome Res 5:196-201. 2006..The most abundant class of zinc-binding proteins in humans is that of zinc-fingers, with Cys4 and Cys2His2 being the most common types of coordination environment...
A bioinformatics view of zinc enzymesClaudia Andreini
Magnetic Resonance Center CERM University of Florence, Via L Sacconi 6, Sesto Fiorentino, Italy
J Inorg Biochem 111:150-6. 2012....
Minimal functional sites allow a classification of zinc sites in proteinsClaudia Andreini
Magnetic Resonance Center, University of Florence, Sesto Fiorentino, Italy
PLoS ONE 6:e26325. 2011....
A hint to search for metalloproteins in gene banksClaudia Andreini
Magnetic Resonance Center (CERM, University of Florence, Italy
Bioinformatics 20:1373-80. 2004..SUPPLEMENTARY INFORMATION: A table reporting statistics on the MBP identified; a list of all hits retrieved for the four organisms considered; a figure showing the number of hits for the four organisms as a function of I(d)(Global)...
A simple protocol for the comparative analysis of the structure and occurrence of biochemical pathways across superkingdomsClaudia Andreini
Magnetic Resonance Center CERM, University of Florence, Sesto Fiorentino, Italy
J Chem Inf Model 51:730-8. 2011..As examples, we analyzed the pathways for the degradation of organic compounds containing one or two aromatic rings as well as the distribution of some proteins involved in Cu(A) assembly in more than a thousand prokaryotes...
Bioinformatic comparison of structures and homology-models of matrix metalloproteinasesClaudia Andreini
Magnetic Resonance Center (CERM, University of Florence, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy
J Proteome Res 3:21-31. 2004....
MACiE: exploring the diversity of biochemical reactionsGemma L Holliday
EMBL EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
Nucleic Acids Res 40:D783-9. 2012..We present new tools for exploring the data in MACiE and comparing entries as well as new analyses of the data and new searches, many of which can now be accessed via dedicated Perl scripts...
