Lorenzo Alibardi

Summary

Affiliation: University of Bologna
Country: Italy

Publications

  1. ncbi Adaptation to the land: The skin of reptiles in comparison to that of amphibians and endotherm amniotes
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126, Bologna, Italy
    J Exp Zool B Mol Dev Evol 298:12-41. 2003
  2. ncbi Localization and characterization of specific cornification proteins in avian epidermis
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Bologna, Italy
    Cells Tissues Organs 178:204-15. 2004
  3. doi Granulocytes of reptilian sauropsids contain beta-defensin-like peptides: a comparative ultrastructural survey
    Lorenzo Alibardi
    Comparative Histolab and Dipartimento di Biologia, University of Bologna, Bologna 40126, Italy
    J Morphol 274:877-86. 2013
  4. pmc Evolution of hard proteins in the sauropsid integument in relation to the cornification of skin derivatives in amniotes
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Italy
    J Anat 214:560-86. 2009
  5. doi Ultrastructural and immunocytochemical detection of keratins and extracellular matrix proteins in lizard skin cultured in vitro
    Lorenzo Alibardi
    Dipartimento di Biologia, University of Bologna, Bologna, Italy
    Tissue Cell 44:122-31. 2012
  6. pmc Expression of beta-keratin mRNAs and proline uptake in epidermal cells of growing scales and pad lamellae of gecko lizards
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, Bologna, Italy
    J Anat 211:104-16. 2007
  7. ncbi Skin structure and cornification proteins in the soft-shelled turtle Trionyx spiniferus
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Italy
    Zoology (Jena) 109:182-95. 2006
  8. ncbi Immunolocalization and characterization of cornification proteins in snake epidermis
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Bologna, Italy
    Anat Rec A Discov Mol Cell Evol Biol 282:138-46. 2005
  9. ncbi Distribution of caspase-14 in epidermis and hair follicles is evolutionarily conserved among mammals
    Lorenzo Alibardi
    Department of Biology, University of Bologna, Bologna, Italy
    Anat Rec A Discov Mol Cell Evol Biol 286:962-73. 2005
  10. doi Cell culture from lizard skin: a tool for the study of epidermal differentiation
    Elisabetta Polazzi
    Dipartimento di Biologia Evoluzionistica Sperimentale, Via Selmi 3, University of Bologna, 40126 Bologna, Italy
    Tissue Cell 43:350-8. 2011

Detail Information

Publications75

  1. ncbi Adaptation to the land: The skin of reptiles in comparison to that of amphibians and endotherm amniotes
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126, Bologna, Italy
    J Exp Zool B Mol Dev Evol 298:12-41. 2003
    ..The study of the molecules involved in the dermo-epidermal interactions in reptilian skin and the molecular biology of epidermal proteins are among the most urgent future areas of research in the biology of reptilian skin...
  2. ncbi Localization and characterization of specific cornification proteins in avian epidermis
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Bologna, Italy
    Cells Tissues Organs 178:204-15. 2004
    ..These data on apteric epidermis support the hypothesis of an evolution of the apteric and interfollicular epidermis from the expansion of hinge regions of protoavian archosaurians...
  3. doi Granulocytes of reptilian sauropsids contain beta-defensin-like peptides: a comparative ultrastructural survey
    Lorenzo Alibardi
    Comparative Histolab and Dipartimento di Biologia, University of Bologna, Bologna 40126, Italy
    J Morphol 274:877-86. 2013
    ....
  4. pmc Evolution of hard proteins in the sauropsid integument in relation to the cornification of skin derivatives in amniotes
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Italy
    J Anat 214:560-86. 2009
    ..In therapsids-mammals, mutations of the ancestral proteins formed the high glycine-tyrosine or the high cysteine proteins but no core-box was produced in the matrix proteins of the hard corneous material of mammalian derivatives...
  5. doi Ultrastructural and immunocytochemical detection of keratins and extracellular matrix proteins in lizard skin cultured in vitro
    Lorenzo Alibardi
    Dipartimento di Biologia, University of Bologna, Bologna, Italy
    Tissue Cell 44:122-31. 2012
    ....
  6. pmc Expression of beta-keratin mRNAs and proline uptake in epidermal cells of growing scales and pad lamellae of gecko lizards
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, Bologna, Italy
    J Anat 211:104-16. 2007
    ..The rapid replacement of setae ensures the continuous usage of the gecko's adhesive devices, the pad lamellae, during most of their active life...
  7. ncbi Skin structure and cornification proteins in the soft-shelled turtle Trionyx spiniferus
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Italy
    Zoology (Jena) 109:182-95. 2006
    ..Thus, the shell makes the animal more streamlined for swimming...
  8. ncbi Immunolocalization and characterization of cornification proteins in snake epidermis
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Bologna, Italy
    Anat Rec A Discov Mol Cell Evol Biol 282:138-46. 2005
    ..No cross-reactivity was seen using an antibody against feather beta-keratin, indicating absence of a common epitope between snake and feather keratins...
  9. ncbi Distribution of caspase-14 in epidermis and hair follicles is evolutionarily conserved among mammals
    Lorenzo Alibardi
    Department of Biology, University of Bologna, Bologna, Italy
    Anat Rec A Discov Mol Cell Evol Biol 286:962-73. 2005
    ..The association of caspase-14 with keratohyalin and trichohyalin granules may indicate a specific role of caspase-14 in the maturation of these keratinocyte-specific structures...
  10. doi Cell culture from lizard skin: a tool for the study of epidermal differentiation
    Elisabetta Polazzi
    Dipartimento di Biologia Evoluzionistica Sperimentale, Via Selmi 3, University of Bologna, 40126 Bologna, Italy
    Tissue Cell 43:350-8. 2011
    ....
  11. doi Ultrastructure of the feather follicle in relation to the formation of the rachis in pennaceous feathers
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Via Selmi 3, 40126, Bologna, Italy
    Anat Sci Int 85:79-91. 2010
    ..In general a thin cortex is formed in those sections of the rachis where barbs are absent, and the feather keratin positive layer increases in the basal part of the feather, the calamus...
  12. ncbi Immunolocalization and characterization of beta-keratins in growing epidermis of chelonians
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Italy
    Tissue Cell 38:53-63. 2006
    ....
  13. ncbi Fine structure of marsupial hairs, with emphasis on trichohyalin and the structure of the inner root sheath
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126, Bologna, Italy
    J Morphol 261:390-402. 2004
    ..The role of cells of the IRS in sculpturing the fiber cuticle and in the mechanism of shedding that allows the exit of hair on the epidermal surface in mammals are discussed...
  14. doi Gap and tight junctions in the formation of feather branches: A descriptive ultrastructural study
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Italy
    Ann Anat 192:251-8. 2010
    ..A discussion of the role of gap and tight junctions during feather morphogenesis is presented...
  15. ncbi Observations on the histochemistry and ultrastructure of regenerating caudal epidermis of the tuatara Sphenodon punctatus (Sphenodontida, Lepidosauria, Reptilia)
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Bologna 40126, Italy
    J Morphol 256:134-45. 2003
    ..Observed differences between posttrauma scale neogenesis and scale embryogenesis are responses to functional problems involved in, respectively, restoring, or forming, a barrier to CWL while accommodating rapid somatic growth...
  16. pmc Comparative aspects of the inner root sheath in adult and developing hairs of mammals in relation to the evolution of hairs
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Via Selmi 3, 40126, Italy
    J Anat 205:179-200. 2004
    ..It is speculated that the progressive reduction of the extended dermal papilla of reptilian scales into small and deep papillae of therapsid reptiles produced hairs in mammals...
  17. ncbi Immunological characterization of a newly developed antibody for localization of a beta-keratin in turtle epidermis
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126 Bologna, Italy
    J Exp Zool B Mol Dev Evol 308:200-8. 2007
    ..The specificity for turtle beta-keratin suggests that the antiserum recognizes some epitope/s specific for chelonians beta-keratins, and that it also variably recognizes other reptilian and avian beta-keratins...
  18. ncbi Hard cornification in reptilian epidermis in comparison to cornification in mammalian epidermis
    Lorenzo Alibardi
    Dipartimento di Biologia, University of Bologna, Bologna, Italy
    Exp Dermatol 16:961-76. 2007
    ..The latter evolved as glycine-tyrosine-rich, sulphur-rich, and ultra-sulphur-rich proteins that are used for building hairs, horns and nails...
  19. doi Ultrastructural localization of hair keratin homologs in the claw of the lizard Anolis carolinensis
    Lorenzo Alibardi
    Dipartimento di Biologia, University of Bologna, Via Selmi 3, 40126, Bologna, Italy
    J Morphol 272:363-70. 2011
    ..The data on the ultrastructural localization of hair keratin homologs facilitate a comparison of lizard claws and mammalian hard epidermal appendages containing hair keratins...
  20. ncbi Differentiation of the epidermis in turtle: an immunocytochemical, autoradiographic and electrophoretic analysis
    Lorenzo Alibardi
    Department of Biology, University of Bologna, Via Selmi 3, 40126 Bologna, Italy
    Acta Histochem 106:379-95. 2004
    ..In conclusion, our study suggests that proteins with epitopes that they have in common with cornification proteins of mammalian epidermis are also present in the epidermis of turtle...
  21. doi Cornification of the pulp epithelium and formation of pulp cups in downfeathers and regenerating feathers
    Lorenzo Alibardi
    Department of Evolutionary and Experimental Biology, University of Bologna, Via Selmi 3, 40126 Bologna, Italy
    Anat Sci Int 84:269-79. 2009
    ..The role of the cornified pulp epithelium is to limit water loss and to form a microbe barrier before the mature feather is moulted...
  22. ncbi Keratinization of sheath and calamus cells in developing and regenerating feathers
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Via Selmi 3, 40126, Italy
    Ann Anat 189:583-95. 2007
    ..The modality of cornification in feathers is compared to the process of hard cornification of reptilian scales and claws and mammalian hairs and nails...
  23. ncbi Distribution and characterization of keratins in the epidermis of the tuatara (Sphenodon punctatus; Lepidosauria, Reptilia)
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Italy
    Zoolog Sci 23:801-7. 2006
    ..Beta-keratins may have both a fibrous and a matrix role in forming the hard texture of corneoum scales in this ancient species, as well as in more recently evolved reptiles...
  24. ncbi Ultrastructural localization of histidine-labelled interkeratin matrix during keratinization of amphibian epidermis
    Lorenzo Alibardi
    Department of Evolutionary Experimental Biology, University of Bologna, Bologna, Italy
    Acta Histochem 105:273-83. 2003
    ..It is unknown whether sulphur is derived from either sulphated mucins, or disulphide bonds in aggregated keratins, or specific sulphur-rich proteins...
  25. doi Immunolocalization of keratin-associated beta-proteins (beta-keratins) in the regenerating lizard epidermis indicates a new process for the differentiation of the epidermis in lepidosaurians
    Lorenzo Alibardi
    Comparative Histolab and Department of Biology, University of Bologna, Bologna, Italy
    J Morphol 273:1272-9. 2012
    ..The differential accumulation of beta-proteins on the alpha-keratin cytoskeleton scaffold and not the alternance of beta- with alpha-keratins allow the differentiation of different epidermal layers...
  26. doi Immunolocalization of keratin-associated beta-proteins in developing epidermis of lizard suggests that adhesive setae contain glycine--cysteine-rich proteins
    Lorenzo Alibardi
    Comparative Histolab and Department of Biology, University of Bologna, Bologna, Italy
    J Morphol 274:97-107. 2013
    ..This result suggests that the differential accumulation of keratin-associated beta-proteins over the alpha-keratin network determines differences in properties of the stratified layers of the epidermis of lizards...
  27. doi Cornification in reptilian epidermis occurs through the deposition of keratin-associated beta-proteins (beta-keratins) onto a scaffold of intermediate filament keratins
    Lorenzo Alibardi
    Comparative Histolab and Department of Biology, University of Bologna, Italy
    J Morphol 274:175-93. 2013
    ....
  28. doi Perspectives on hair evolution based on some comparative studies on vertebrate cornification
    Lorenzo Alibardi
    Comparative Histolab and Dipartimento di Biologia, University of Bologna, Bologna, Italy
    J Exp Zool B Mol Dev Evol 318:325-43. 2012
    ..The hypothesis indicates that in a following stage, the medulla was obliterated or replaced by cortical cells while the external part of the cortex formed a cuticular surface due to the different growth rate with inner root sheath cells...
  29. doi Wounding in lizards results in the release of beta-defensins at the wound site and formation of an antimicrobial barrier
    Lorenzo Alibardi
    Comparative Histolab and Dipartimento di Biologia, University of Bologna, Italy
    Dev Comp Immunol 36:557-65. 2012
    ..The production of beta-defensins from granulocytes would allow protection of exposed tissues from microbial invasion avoiding a persistent inflammation, a process that leads to tissue regeneration...
  30. doi Immunolocalization of FGF1 and FGF2 in the regenerating tail of the lizard Lampropholis guichenoti: implications for FGFs as trophic factors in lizard tail regeneration
    Lorenzo Alibardi
    Department of Biology, University of Bologna, Bologna, Italy
    Acta Histochem 112:459-73. 2010
    ..The present study suggests that FGFs produced in the regenerating epidermis, spinal cord and nerves can stimulate tail regeneration in lizards...
  31. ncbi Structural and immunocytochemical characterization of keratinization in vertebrate epidermis and epidermal derivatives
    Lorenzo Alibardi
    Department of Experimental and Evolutionary Biology, University of Bologna, 40126 Bologna, Italy
    Int Rev Cytol 253:177-259. 2006
    ..The evolution of these small proteins represents the more recent variation of the process of cornification in vertebrates...
  32. ncbi Observations on the histochemistry and ultrastructure of the epidermis of the tuatara, Sphenodon punctatus (Sphenodontida, Lepidosauria, Reptilia): a contribution to an understanding of the lepidosaurian epidermal generation and the evolutionary origin of
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Bologna 40126, Italy
    J Morphol 256:111-33. 2003
    ....
  33. ncbi Hard (Beta-)keratins in the epidermis of reptiles: composition, sequence, and molecular organization
    Mattia Toni
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Italy, and Dipartimento di Biologia, University of Padova, Italy
    J Proteome Res 6:3377-92. 2007
    ..In birds, a small beta-keratin has allowed the formation of feathers. It is suggested that beta-keratins represent the reptilian counterpart of keratin associated or matrix proteins present in mammalian hairs, claws, and horns...
  34. ncbi Ultrastructural and immunohistochemical observations on the process of horny growth in chelonian shells
    Lorenzo Alibardi
    Department of Biology, University of Bologna, Via Selmi 3, 40126 Bologna, Italy
    Acta Histochem 108:149-62. 2006
    ..The stratified layers gradually disappear toward the growing border of the shell. The mode of growth of horny scutes in these different species of chelonians is discussed...
  35. pmc Ultrastructural distribution of glycinergic and GABAergic neurons and axon terminals in the rat dorsal cochlear nucleus, with emphasis on granule cell areas
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Italy
    J Anat 203:31-56. 2003
    ..Pyramidal cells convey an excitatory signal from the DCN to higher mesencephalic nuclei for further elaboration of the acoustic signal...
  36. ncbi Wedge cells during regeneration of juvenile and adult feathers and their role in carving out the branching pattern of barbs
    Lorenzo Alibardi
    Dipartimento di Biologia, University of Bologna, Via Selmi 3, 40126 Bologna, Italy
    Ann Anat 189:234-42. 2007
    ..Eventually, the disappearance of wedge cell scaffolding determines the regular spacing of barbs attached to the rachis in order to form a close vane...
  37. ncbi Synthesis of interkeratin matrix in differentiating lizard epidermis: an ultrastructural autoradiographic study after injection of tritiated proline and histidine
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Via Selmi 3, 40126 Bologna, Italy
    J Morphol 259:182-97. 2004
    ..This study indicates that a functional stratum corneum in the epidermis of amniotes originates only after the association of matrix and corneous cell envelope proteins with the original keratin scaffold of keratinocytes...
  38. ncbi Wound keratins in the regenerating epidermis of lizard suggest that the wound reaction is similar in the tail and limb
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Italy
    J Exp Zool A Comp Exp Biol 303:845-60. 2005
    ....
  39. ncbi Review: cytological characteristics of commissural and tuberculo-ventral neurons in the rat dorsal cochlear nucleus
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, Via Selmi 3, University of Bologna, 40126 Bologna, Italy
    Hear Res 216:73-80. 2006
    ..Putative COM-mossy fibers reach the granule areas of the DCN, including unipolar brush cell dendrites, another possible excitatory commissural pathway...
  40. ncbi Dermo-epidermal interactions in reptilian scales: speculations on the evolution of scales, feathers, and hairs
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Via Selmi 3, 40126 Bologna, Italy
    J Exp Zool B Mol Dev Evol 302:365-83. 2004
    ..The latter has invaginated in association with the collar epidermis from which feathers were produced...
  41. doi Cytochemical and molecular characteristics of the process of cornification during feather morphogenesis
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, Via Selmi 3, University of Bologna, 40126 Bologna, Italy
    Prog Histochem Cytochem 43:1-69. 2008
    ..Feather morphogenesis suggests possible stages for feather evolution and diversification from hair-like outgrowths of the skin found in fossils of pro-avian archosaurians...
  42. ncbi Immunological characterization and fine localization of a lizard beta-keratin
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Bologna, Italy
    J Exp Zool B Mol Dev Evol 306:528-38. 2006
    ..This result indicates that beta-keratins among different reptilian groups posses different immunoreactive regions...
  43. ncbi Cytochemical, biochemical and molecular aspects of the process of keratinization in the epidermis of reptilian scales
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, Via Selmi 3, University of Bologna, 40126 Bologna, Italy
    Prog Histochem Cytochem 40:73-134. 2006
    ..The evolution of these small proteins in lepidosaurians, chelonians and archosaurians represent the next step to understand the evolution of cornification in reptiles and derived amniotes (birds and mammals)...
  44. ncbi Scale keratin in lizard epidermis reveals amino acid regions homologous with avian and mammalian epidermal proteins
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Bologna, Italy
    Anat Rec A Discov Mol Cell Evol Biol 288:734-52. 2006
    ..These small proteins produce a hard type of corneous material due to their dense packing among cytokeratin filaments...
  45. ncbi Fine structure and immunocytochemistry of monotreme hairs, with emphasis on the inner root sheath and trichohyalin-based cornification during hair evolution
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126, Bologna, Italy
    J Morphol 261:345-63. 2004
    ..Based on comparative studies of reptilian and mammalian skin, a speculative hypothesis on the evolution of the IRS and hairs from the skin of synapsid reptiles is presented...
  46. ncbi Distribution of keratin and associated proteins in the epidermis of monotreme, marsupial, and placental mammals
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126, Bologna, Italy
    J Morphol 258:49-66. 2003
    ..Nevertheless, the mechanism of redistribution of such proteins during maturation of monotreme keratinocytes is different from, perhaps more primitive, or less specialized, than that in the epidermis of eutherian mammals...
  47. ncbi Morphological and cellular aspects of tail and limb regeneration in lizards. A model system with implications for tissue regeneration in mammals
    Lorenzo Alibardi
    Universita di Bologna, Dipto Bilogia Evoluzionistica Sperimentale, Italy
    Adv Anat Embryol Cell Biol 207:iii, v-x, 1-109. 2010
    ..The review concludes by stressing the importance of the lizard model of tissue regeneration for medical studies and applications...
  48. ncbi Keratinization and lipogenesis in epidermal derivatives of the zebrafinch, Taeniopygia guttata castanotis (Aves, Passeriformes, Ploecidae) during embryonic development
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126 Bologna, Italy
    J Morphol 251:294-308. 2002
    ..The contribution of lipids or lipoprotein to the initial aggregation of beta-keratin molecules is discussed...
  49. ncbi Ultrastructure of the embryonic snake skin and putative role of histidine in the differentiation of the shedding complex
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126, Bologna, Italy
    J Morphol 251:149-68. 2002
    ..It is suggested that the shedding complex in lepidosaurian reptiles has evolved after the production of a histidine-rich protein and of a beta-keratin layer beneath the former alpha-layer...
  50. doi Immunolocalization of specific keratin associated beta-proteins (beta-keratins) in the adhesive setae of Gekko gecko
    Lorenzo Alibardi
    Comparative Histolab and Dipartimento di Biologia, University of Bologna, Bologna, Italy
    Tissue Cell 45:231-40. 2013
    ..The selection and improvement of these proteins during the evolution of geckos may have represented a successful factor for the survival and ecological adaptations of these climbing lizards...
  51. doi Immunolocalization of junctional proteins in human hairs indicates that the membrane complex stabilizes the inner root sheath while desmosomes contact the companion layer through specific keratins
    Lorenzo Alibardi
    Comparative Histolab and Department of Biology, University of Bologna, Italy
    Acta Histochem 115:519-26. 2013
    ..This suggests that this elastic type of keratin is present at desmosome junctions during the movements of the companion layer along the slippage plane of the hair shaft...
  52. doi Immunolocalization of keratin-associated beta-proteins (beta-keratins) in pad lamellae of geckos suggest that glycine-cysteine-rich proteins contribute to their flexibility and adhesiveness
    Lorenzo Alibardi
    Comparative Histolab and Department of Biology, University of Bologna, Italy
    J Exp Zool A Ecol Genet Physiol 319:166-78. 2013
    ....
  53. ncbi Immunocytochemistry of glycine in small neurons of the granule cell areas of the guinea pig dorsal cochlear nucleus: a post-embedding ultrastructural study
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Via Selmi 3, 40126, Bologna, Italy
    Histochem J 34:423-34. 2002
    ..The latter are not contacted by large mossy-like glycine terminals...
  54. ncbi Immunocytochemical and autoradiographic studies on the process of keratinization in avian epidermis suggests absence of keratohyalin
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Via Selmi 3, 40126 Bologna, Italy
    J Morphol 259:238-53. 2004
    ..These observations suggest that low amounts of matrix proteins are present among keratin bundles of avian keratinocytes and that keratohyalin granules are absent...
  55. ncbi Proliferation in the epidermis of chelonians and growth of the horny scutes
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, Universita di Bologna, Bologna 40126, Italy
    J Morphol 265:52-69. 2005
    ..The latter contains lipids and eventually flakes off, determining shedding of the above outer corneous layer in late spring or summer...
  56. ncbi Ultrastructural localization of tritiated histidine in down feathers of the chick
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, Universita di Bologna, Bologna, Italia
    Cells Tissues Organs 182:35-47. 2006
    ..This observation suggests that histidine-labeled material contributes to the formation of long keratin filaments with axial orientation that are utilized for the elongation of barb and barbule cells...
  57. ncbi Cell structure of barb ridges in down feathers and juvenile wing feathers of the developing chick embryo: barb ridge modification in relation to feather evolution
    Lorenzo Alibardi
    Dipartimento di Biologia, University of Bologna, Via Selmi 3, 40126 Bologna, Italy
    Ann Anat 188:303-18. 2006
    ..This process initially produced variably branched down feathers and later, after barb ridge fusion, a rachis. From the modulation in the pattern of barb ridge formation various pennaceous feathers later evolved...
  58. ncbi Alpha- and beta-keratins of the snake epidermis
    Mattia Toni
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Via Selmi 3, I 40126 Bologna, Italy
    Zoology (Jena) 110:41-7. 2007
    ..The study also suggests that more forms of beta-keratins (more than three different types) are present in the epidermis of snakes...
  59. doi Ultrastructural immunolocalization of involucrin in the medulla and inner root sheath of the human hair
    Lorenzo Alibardi
    Comparative Histolab and Dipartimento di Biologia, University of Bologna, Italy
    Ann Anat 194:345-50. 2012
    ..Therefore, together with trichohyalin, the cross-linking due to involucrin is also responsible for the mechanical resistance of the corneous trabeculae present among the empty spaces of the medulla of the human hair...
  60. ncbi Immunocytochemical analysis of beta keratins in the epidermis of chelonians, lepidosaurians, and archosaurians
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126, Bologna, Italy
    J Exp Zool 293:27-38. 2002
    ..These immunocytochemical results suggest that the 3-nm beta keratin filaments of the reptilian integument are phylogenetically related to those found in avian epidermal appendages...
  61. ncbi Loricrin-like immunoreactivity during keratinization in lizard epidermis
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126, Bologna, Italy
    J Morphol 254:132-8. 2002
    ....
  62. ncbi Immunocytochemical localization of keratins, associated proteins and uptake of histidine in the epidermis of fish and amphibians
    Lorenzo Alibardi
    Department of Evolutionary Experimental Biology, University of Bologna, Italy
    Acta Histochem 104:297-310. 2002
    ..Although the cell membrane of superficial corneous cells of amphibian epidermis became thicker, the absence of loricrine immunolabelling suggests that a cell corneous envelope containing this protein is not present or undetectable...
  63. ncbi Keratinization of the epidermis of the Australian lungfish Neoceratodus forsteri (dipnoi)
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Bologna, Italy
    J Morphol 256:13-22. 2003
    ....
  64. ncbi Presence of putative histidine-rich proteins in the amphibian epidermis
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126, Bologna, Italy
    J Exp Zool A Comp Exp Biol 297:105-17. 2003
    ....
  65. doi Claw development and cornification in the passeraceous bird zebrafinch (Taeniatopygia guttata castanotis)
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Via Selmi 3, 40126, Bologna, Italy
    Anat Sci Int 84:189-99. 2009
    ..The latter is shed at hatching leaving the pointed claw made of harder corneous layers in the unguis side of the claw...
  66. doi Cell biology of adhesive setae in gecko lizards
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Via Selmi 3, 40126 Bologna, Italy
    Zoology (Jena) 112:403-24. 2009
    ..The terminals branching off each seta may derive from the organization of the cytoskeleton and from the mechanical separation of keratin bundles located at the terminal apex of setae...
  67. ncbi alpha-Tubulin and acetylated alpha-tubulin during ovarian follicle differentiation in the lizard Podarcis sicula Raf
    Maria Gabriella Maurizii
    Dipartimento di Biologia Evoluzionistica Sperimentale, Universita degli Studi di Bologna, Via Selmi N degrees 3, I 40126 Bologna, Italy
    J Exp Zool A Comp Exp Biol 301:532-41. 2004
    ..We have also identified the colocalization of alpha-tubulin with keratin in the cortical region of the oocyte, in particular when the cortex is engaged in the uptake of the yolk proteins...
  68. ncbi Ultrastructural localization of caspase-14 in human epidermis
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Bologna, Italy
    J Histochem Cytochem 52:1561-74. 2004
    ..These observations will allow focusing efforts of biochemical substrate screening on a subset of proteins localizing to distinct compartments of terminally differentiated keratinocytes...
  69. ncbi Histidine uptake in the epidermis of lizards and snakes in relation to the formation of the shedding complex
    Lorenzo Alibardi
    Dipartimento di Biologia, University of Bologna, 40126 Bologna, Italy
    J Exp Zool 292:331-44. 2002
    ..The present study suggests that, in the epidermis of lepidosaurian reptiles, the synthesis of a histidine-rich protein is involved in the formation of the shedding layer and, as in mammals, in a-keratinization...
  70. ncbi Differentiation of snake epidermis, with emphasis on the shedding layer
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, 40126, Bologna, Italy
    J Morphol 264:178-90. 2005
    ..In conclusion, beta-keratin, histidine-rich, and sulfur-rich proteins contribute to form snake microornamentations...
  71. pmc Keratinization and ultrastructure of the epidermis of late embryonic stages in the alligator (Alligator mississippiensis)
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Italy
    J Anat 201:71-84. 2002
    ..The cross-reactivity of the beta-antibody, produced against a chick scale keratin, further shows that avian and crocodilian hard (beta) keratins share common antigenic sites, reflecting a phylogenetic affinity between these taxa...
  72. ncbi Ultrastructure and immunocytochemical characteristics of cells in the octopus cell area of the rat cochlear nucleus: comparison with multipolar cells
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, University of Bologna, Via Selmi 3, 40126 Bologna, Italy
    Ann Anat 185:21-33. 2003
    ..The present study suggests that octopus cells are a special type of excitatory D-multipolar neuron confined to the octopus cell area and mainly innervated by glutamatergic cochlear nerve terminals...
  73. ncbi Isolation of a mRNA encoding a glycine-proline-rich beta-keratin expressed in the regenerating epidermis of lizard
    Luisa Dalla Valle
    Department of Biology, University of Padova, Italy
    Dev Dyn 234:934-47. 2005
    ..The synthesis of beta-keratin from its mRNA occurs among ribosomes or is associated with the surface of beta-keratin filaments...
  74. ncbi Beta-keratins of differentiating epidermis of snake comprise glycine-proline-serine-rich proteins with an avian-like gene organization
    Luisa Dalla Valle
    Dipartimento di Biologia, Universita di Padova, Padova, Italy
    Dev Dyn 236:1939-53. 2007
    ..This region was possibly present in basic reptiles that originated reptiles and birds...
  75. ncbi Cloning and characterization of scale beta-keratins in the differentiating epidermis of geckoes show they are glycine-proline-serine-rich proteins with a central motif homologous to avian beta-keratins
    Luisa Dalla Valle
    Dipartimento di Biologia, Universita di Padova, Padova, Italy
    Dev Dyn 236:374-88. 2007
    ..PCR analysis showed that the genes are presumably located in tandem along the DNA and are transcribed from the same DNA strand like in avian beta-keratins...