Research Topics
Species | A AgostoniSummaryAffiliation: University of Milan Country: Italy Publications
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Detail Information
Publications
[The kinin system: biological mechanisms and clinical implications]A Agostoni
Dipartimento di Medicina Interna, Universita, IRCCS Ospedale Maggiore, Milano
Recenti Prog Med 92:764-73. 2001..The study of the kinin system in clinical field, which had been limited by methodological difficulties, has now received an important stimulus by the recent availability of specific and sensitive methods of dosage...
Drug-induced angioedema without urticariaA Agostoni
Department of Internal Medicine, IRCCS Milan Maggiore Hospital, University of Milan, Italy
Drug Saf 24:599-606. 2001..If the acute airway obstruction leads to life-threatening respiratory compromise an emergency cricothyroidotomy must be performed...
Alzheimer's beta-amyloid peptides can activate the early components of complement classical pathway in a C1q-independent mannerL Bergamaschini
Department of Internal Medicine, Maggiore Hospital, IRCCS, Milan, Italy
Clin Exp Immunol 115:526-33. 1999....
Bradykinin in the ascitic fluid of patients with liver cirrhosisM Cugno
Department of Internal Medicine, University of Milan, Maggiore Hospital IRCCS, Via Pace 15, 20122 Milan, Italy
Clin Sci (Lond) 101:651-7. 2001..Activation of the kinin system may therefore be involved in decompensating cirrhosis, but a cause-effect relationship remains to be established...
Parallel reduction of plasma levels of high and low molecular weight kininogen in patients with cirrhosisM Cugno
Department of Internal Medicine, IRCCS Maggiore Hospital, University of Milan, Italy
Thromb Haemost 82:1428-32. 1999..The decrease of important regulatory proteins like kininogens may contribute to the imbalance in coagulation and fibrinolytic systems, which frequently occurs in cirrhotic patients...
The region 1-11 of Alzheimer amyloid-beta is critical for activation of contact-kinin systemL Bergamaschini
Department of Internal Medicine, Ospedale Maggiore, IRCCS, University of Milan, Italy
Neurobiol Aging 22:63-9. 2001....
Angioedema due to angiotensin-converting enzyme inhibitorsA Agostoni
Department of Internal Medicine, University of Milan, IRCCS Ospedale, Maggiore, Italy
Immunopharmacology 44:21-5. 1999..These observations indicate that in ACE-inhibitor-induced angioedema, contrary to hereditary angioedema, the reduction of bradykinin catabolic rate plays a predominant role...
In vitro interaction of C1-inhibitor with thrombinM Cugno
Department of Internal Medicine, IRCCS Maggiore Hospital, University of Milan, Milan, Italy
Blood Coagul Fibrinolysis 12:253-60. 2001....
Consumption of C4b-binding protein (C4BP) during in vivo activation of the classical complement pathwayL Bergamaschini
Department of Internal Medicine, Maggiore Hospital IRCCS, University of Milan, Milan, Italy
Clin Exp Immunol 116:220-4. 1999..The results of this study indicate that C4BP is consumed in vivo during acute, and possibly during chronic activation of the C' classical pathway, and that this protein, after interaction with C4b, not longer circulates in plasma...
Increase of bradykinin in plasma of patients undergoing cardiopulmonary bypass: the importance of lung exclusionM Cugno
Department of Internal Medicine, IRCCS Maggiore Hospital, University of Milan, Italy
Chest 120:1776-82. 2001..CONCLUSIONS: During CPB, there is a progressive increase of plasma bradykinin that is at least partially due to reduced catabolism as a consequence of shunting the lungs. The increase in bradykinin may contribute to the fall in BP...
Nonsense mutations affect C1 inhibitor messenger RNA levels in patients with type I hereditary angioneurotic edemaD Frangi
Division of Immunology, Children s Hospital, Boston, Massachusetts
J Clin Invest 88:755-9. 1991..This elevation may be due to the decreased catabolism of the mutant transcript...
