Silvano Adami

Summary

Affiliation: University of Verona
Country: Italy

Publications

  1. ncbi request reprint A multicenter cross sectional study on bone mineral density in rheumatoid arthritis. Italian Study Group on Bone Mass in Rheumatoid Arthritis
    L Sinigaglia
    Department of Rheumatology, Istituto Ortopedico Gaetano, Pini, Milan, Italy
    J Rheumatol 27:2582-9. 2000
  2. ncbi request reprint Protelos: nonvertebral and hip antifracture efficacy in postmenopausal osteoporosis
    S Adami
    Rheumatology Rehabilitation Unit of the University of Verona, Valeggio sul Mincio, Italy
    Bone 38:23-7. 2006
  3. doi request reprint Treatment thresholds for osteoporosis and reimbursability criteria: perspectives associated with fracture risk-assessment tools
    Silvano Adami
    Rheumatology Unit, Department of Medicine, University of Verona, Policlinico Borgo Roma, Piazzale Scuro, 37134, Verona, Italy
    Calcif Tissue Int 93:195-200. 2013
  4. doi request reprint Duration of treatment for osteoporosis
    Luca Idolazzi
    Rheumatology Unit, University of Verona, Verona, Italy
    Reumatismo 65:22-35. 2013
  5. ncbi request reprint Full length parathyroid hormone, PTH(1-84), for the treatment of severe osteoporosis in postmenopausal women
    Silvano Adami
    Rheumatology Department, University of Verona, Valeggio Sul MincioHospital VR, Verona, Italy
    Curr Med Res Opin 24:3259-74. 2008
  6. ncbi request reprint [Italian guidelines for the diagnosis and treatment of Paget's disease of bone]
    S Adami
    Reumatologia, Universita di Verona, Verona, Italia
    Reumatismo 59:153-68. 2007
  7. ncbi request reprint Validation and further development of the WHO 10-year fracture risk assessment tool in Italian postmenopausal women: project rationale and description
    S Adami
    Rheumatology Unit, University of Verona, Italy
    Clin Exp Rheumatol 28:561-70. 2010
  8. ncbi request reprint Relationship between lipids and bone mass in 2 cohorts of healthy women and men
    S Adami
    Rheumatology Unit, Valeggio S M, University of Verona, Italy
    Calcif Tissue Int 74:136-42. 2004
  9. ncbi request reprint Ibandronate: new options in the treatment of osteoporosis
    S Adami
    Department of Rheumatology, University of Verona, Verona, Italy
    Drugs Today (Barc) 39:877-86. 2003
  10. ncbi request reprint Efficacy and safety of ibandronate given by intravenous injection once every 3 months
    S Adami
    University of Verona, Valeggio, Italy
    Bone 34:881-9. 2004

Detail Information

Publications108 found, 100 shown here

  1. ncbi request reprint A multicenter cross sectional study on bone mineral density in rheumatoid arthritis. Italian Study Group on Bone Mass in Rheumatoid Arthritis
    L Sinigaglia
    Department of Rheumatology, Istituto Ortopedico Gaetano, Pini, Milan, Italy
    J Rheumatol 27:2582-9. 2000
    ..To determine the frequency of osteoporosis in a large cohort of women with rheumatoid arthritis (RA) and to investigate the main determinants of bone mineral density (BMD) and risk factors for vertebral fractures in this population...
  2. ncbi request reprint Protelos: nonvertebral and hip antifracture efficacy in postmenopausal osteoporosis
    S Adami
    Rheumatology Rehabilitation Unit of the University of Verona, Valeggio sul Mincio, Italy
    Bone 38:23-7. 2006
    ..The study demonstrates that strontium ranelate treatment offers a safe and effective means of reducing the risk of nonvertebral and hip fractures in postmenopausal women with osteoporosis...
  3. doi request reprint Treatment thresholds for osteoporosis and reimbursability criteria: perspectives associated with fracture risk-assessment tools
    Silvano Adami
    Rheumatology Unit, Department of Medicine, University of Verona, Policlinico Borgo Roma, Piazzale Scuro, 37134, Verona, Italy
    Calcif Tissue Int 93:195-200. 2013
    ..Here, we elaborate an algorithm to convert vertebral and nonvertebral fractures to the "major fractures" of FRAX, and this allows a cost-effectiveness assessment for each drug. ..
  4. doi request reprint Duration of treatment for osteoporosis
    Luca Idolazzi
    Rheumatology Unit, University of Verona, Verona, Italy
    Reumatismo 65:22-35. 2013
    ..The results of the review highlight differences among the available drugs and the practical clinical consequences also in terms of cost-effectiveness...
  5. ncbi request reprint Full length parathyroid hormone, PTH(1-84), for the treatment of severe osteoporosis in postmenopausal women
    Silvano Adami
    Rheumatology Department, University of Verona, Valeggio Sul MincioHospital VR, Verona, Italy
    Curr Med Res Opin 24:3259-74. 2008
    ....
  6. ncbi request reprint [Italian guidelines for the diagnosis and treatment of Paget's disease of bone]
    S Adami
    Reumatologia, Universita di Verona, Verona, Italia
    Reumatismo 59:153-68. 2007
    ..The document provides the most updated recommendations based primarily on the "evidence-based- medicine" but also on the Italian regulation for the diagnostic procedures and on the available medical treatments...
  7. ncbi request reprint Validation and further development of the WHO 10-year fracture risk assessment tool in Italian postmenopausal women: project rationale and description
    S Adami
    Rheumatology Unit, University of Verona, Italy
    Clin Exp Rheumatol 28:561-70. 2010
    ..The new tool will be offered for the routine clinical use only at the completion of the DeFRA project, requiring the prospective collection of at least 60.000 patient-years. Here we report the rational and the design of the project...
  8. ncbi request reprint Relationship between lipids and bone mass in 2 cohorts of healthy women and men
    S Adami
    Rheumatology Unit, Valeggio S M, University of Verona, Italy
    Calcif Tissue Int 74:136-42. 2004
    ..The interpretation of this association remains hypothetical but it might open new perspectives for understanding the mechanisms controlling bone metabolism...
  9. ncbi request reprint Ibandronate: new options in the treatment of osteoporosis
    S Adami
    Department of Rheumatology, University of Verona, Verona, Italy
    Drugs Today (Barc) 39:877-86. 2003
    ..In this review, the data obtained with ibandronate, using both oral administration and intravenous injection, for the treatment and prevention of postmenopausal osteoporosis are summarized...
  10. ncbi request reprint Efficacy and safety of ibandronate given by intravenous injection once every 3 months
    S Adami
    University of Verona, Valeggio, Italy
    Bone 34:881-9. 2004
    ..Ongoing studies aim to further establish the efficacy and convenience of intermittent intravenous ibandronate injections in postmenopausal osteoporosis...
  11. doi request reprint Insulin-like growth factor-1 is associated with bone formation markers, PTH and bone mineral density in healthy premenopausal women
    Silvano Adami
    Rheumatology Unit, Dpt of Scienze biomediche e chirurgiche, University of Verona, Verona, Italy
    Bone 46:244-7. 2010
    ..In conclusion, in this study we provide evidence of an association between the age-related decline in IGF-I with the progressive decrease in bone formation markers in premenopausal women...
  12. ncbi request reprint Effect of age, weight and lifestyle factors on calcaneal quantitative ultrasound in premenopausal women: the ESOPO study
    S Adami
    Riabilitazione Reumatologica, University of Verona, Verona, Italy
    Calcif Tissue Int 74:317-21. 2004
    ..These findings should help to identify premenopausal women at risk and to design an early strategy for osteoporosis prevention based on eliminating modifiable risks...
  13. doi request reprint [Guidelines on prevention and treatment of vitamin D deficiency. Italian Society for Osteoporosis, Mineral Metabolism and Bone Diseases (SIOMMMS)]
    S Adami
    Unita di Reumatologia, Dipartimento di Medicina, Universita di Verona, Roma, Italia
    Reumatismo 63:129-47. 2011
    ..In pregnant women, vitamin D supplements should be given as in non-pregnant women, but bolus administration (i.e.: single dose >25,000 IU) should be avoided...
  14. ncbi request reprint Effect of raloxifene after recombinant teriparatide [hPTH(1-34)] treatment in postmenopausal women with osteoporosis
    S Adami
    Riabilitazione Reumatologica, University of Verona, Valeggio s Mincio, Verona, Italy
    Osteoporos Int 19:87-94. 2008
    ..Sequential raloxifene prevented rapid bone loss at lumbar spine and further increased bone mineral density (BMD) at femoral neck, whether raloxifene was started immediately or after a one-year delay following teriparatide treatment...
  15. ncbi request reprint Relationship between serum parathyroid hormone, vitamin D sufficiency, age, and calcium intake
    Silvano Adami
    Rheumatologic Rehabilitation, University of Verona, Italy
    Bone 42:267-70. 2008
    ..In elderly individuals not taking calcium supplements in order to keep serum PTH levels strictly within the normal range 25(OH)D serum levels should be maintained above ca. 120 nMol/L...
  16. doi request reprint Vitamin D status and response to treatment in post-menopausal osteoporosis
    S Adami
    Rheumatology Unit, Ospedale di Valeggio, Verona, Italy
    Osteoporos Int 20:239-44. 2009
    ..5-fold increased risk of incidence fracture in vitamin D insufficient as compared to vitamin D repleted postmenopausal osteoporotic women...
  17. doi request reprint Intramuscular neridronate in postmenopausal women with low bone mineral density
    Silvano Adami
    Rheumatology Unit, Ospedale di Valeggio, University of Verona, 37067, Valeggio, Verona, Italy
    Calcif Tissue Int 83:301-7. 2008
    ..The results of this study indicate that IM neridronate might be of value for patients intolerant to oral bisphosphonates and unwilling or unable to undergo intravenous infusion of bisphosphonates...
  18. ncbi request reprint Determinants of bone turnover markers in healthy premenopausal women
    Silvano Adami
    Rheumatology Unit, University of Verona, Ospedale di Valeggio, Valeggio, Verona, Italy
    Calcif Tissue Int 82:341-7. 2008
    ..New normative ranges for serum OC, CTX, and P1NP were identified; and our findings in general impose a redefinition of the criteria for establishing the normal ranges for BTMs...
  19. ncbi request reprint Upper gastrointestinal tract safety of daily oral risedronate in patients taking NSAIDs: a randomized, double-blind, placebo-controlled trial
    Silvano Adami
    Rheumatologic Rehabilitation Unit, University of Verona, Via Santa Maria Crocifissa di Rosa, 37067 Valeggio sul Mincio VR, Italy
    Mayo Clin Proc 80:1278-85. 2005
    ..To evaluate the frequency of upper gastrointestinal (GI) tract adverse events associated with risedronate during two (2-year) randomized, double-blind, parallel-group, placebo-controlled studies...
  20. ncbi request reprint Physical activity and bone turnover markers: a cross-sectional and a longitudinal study
    Silvano Adami
    Rheumatology Unit, Ospedale di Valeggio, University of Verona, 37067, Valeggio, Verona, Italy
    Calcif Tissue Int 83:388-92. 2008
    ..In conclusion, both the cross-sectional and the longitudinal parts of our study demonstrate that even minor changes in physical activity are associated with a clear effect on bone formation markers...
  21. ncbi request reprint Bone health in diabetes: considerations for clinical management
    Silvano Adami
    Faculty of Medicine and Surgery, University of Verona, Verona, Italy
    Curr Med Res Opin 25:1057-72. 2009
    ..The metabolic and endocrine alterations of diabetes adversely affect bone quantity and/or quality and may increase fracture risk...
  22. doi request reprint 25-hydroxy vitamin D levels in healthy premenopausal women: association with bone turnover markers and bone mineral density
    Silvano Adami
    Rheumatology Unit, Ospedale di Valeggio, 37067 Valeggio, Verona, Italy
    Bone 45:423-6. 2009
    ..Vitamin D deficiency is very common in elderly people while there are very few reports on its incidence, determinants and metabolic consequences in young subjects...
  23. doi request reprint Osteoporosis treatment and fracture incidence: the ICARO longitudinal study
    S Adami
    Rheumatology Department, University of Verona, Valeggio Sul Mincio Hospital VR, 37067 Valeggio S Mincio, Verona, Italy
    Osteoporos Int 19:1219-23. 2008
    ..5%/year. This incidence is considerably higher than that observed in randomized clinical trials...
  24. ncbi request reprint The effect of age, weight, and lifestyle factors on calcaneal quantitative ultrasound: the ESOPO study
    Silvano Adami
    Riabilitazione Reumatologica, University of Verona, Ospedale Valeggio, 37067, Verona, Italy
    Osteoporos Int 14:198-207. 2003
    ..Risk factors usually associated to BMD as measured by DXA are also associated to calcaneal bone stiffness as measured by QUS, and most risk factors for osteoporosis usually observed in women are equally applicable to men...
  25. ncbi request reprint Determinants and effects of vitamin D supplementation on serum 25-hydroxy-vitamin D levels in patients with rheumatoid arthritis
    Massimo Varenna
    Rheumatology Unit, Istituto Ortopedico Gaetano Pini, Milano, Italy
    Clin Exp Rheumatol 30:714-9. 2012
    ..This study evaluated factors related with the prescription of vitamin D supplements in RA patients and variables influencing the achievement of adequate vitamin D levels...
  26. ncbi request reprint Short-term effects on bone turnover markers of a single high dose of oral vitamin D₃
    Maurizio Rossini
    Rheumatology Unit, Department of Medicine, University of Verona, Policlinico Borgo Roma, Piazzale Scuro, 10, 37134 Verona, Italy
    J Clin Endocrinol Metab 97:E622-6. 2012
    ....
  27. ncbi request reprint Intravenous bisphosphonate therapy increases radial width in adults with osteogenesis imperfecta
    Davide Gatti
    Rheumatologic Rehabilitation, University of Verona, Verona, Italy
    J Bone Miner Res 20:1323-6. 2005
    ..Neridronate therapy in adult patients with OI significantly increases the cross-sectional area of the proximal radius. This observation may provide an additional explanation for the antifracture efficacy of bisphosphonates...
  28. doi request reprint Sclerostin and DKK1 in primary hyperparathyroidism
    Ombretta Viapiana
    Unit of Rheumatology, University of Verona, P le Scuro 10, 37134, Verona, Italy
    Calcif Tissue Int 92:324-9. 2013
    ..Further studies are warranted in order to verify whether the balance between these two opposite effects on Wnt function might help explain the variable bone involvement among patients with PHPT...
  29. doi request reprint Dose-dependent short-term effects of single high doses of oral vitamin D(3) on bone turnover markers
    Maurizio Rossini
    Rheumatology Unit, Department of Medicine, University of Verona, Policlinico Borgo Roma, Piazzale Scuro, 10, 37134, Verona, Italy
    Calcif Tissue Int 91:365-9. 2012
    ..Our results indicate that the use of a vitamin D bolus exceeding 100,000 IU may be associated with acute increases of sCTX...
  30. doi request reprint Sclerostin and DKK1 in postmenopausal osteoporosis treated with denosumab
    Davide Gatti
    Unit of Rheumatology, University of Verona, Verona, Italy
    J Bone Miner Res 27:2259-63. 2012
    ..This latter observation might explain the continuous increase over 5 years in BMD observed during treatment of postmenopausal osteoporosis with denosumab...
  31. ncbi request reprint Early bisphosphonate treatment in infants with severe osteogenesis imperfecta
    Franco Antoniazzi
    Pediatric Clinic and Rheumatological Rehabilitation, University of Verona, Verona, Italy
    J Pediatr 149:174-9. 2006
    ..To evaluate prospectively the efficacy of bisphosphonate treatment in infants with severe forms of osteogenesis imperfecta (OI)...
  32. ncbi request reprint Marked increases in bone mineral density and biochemical markers of bone turnover in patients with anorexia nervosa gaining weight
    Ombretta Viapiana
    Department of Rheumathology, University of Verona, Valeggio Hospital, 37067 Valeggio S Mincio, Verona, Italy
    Bone 40:1073-7. 2007
    ..If weight is maintained, the overall improvement approach 1 SD within 1 year. The changes in both weight and BMD are correlated with improvements in bone formation markers and diminutions in a marker of bone resorption...
  33. ncbi request reprint Teriparatide treatment in adult patients with osteogenesis imperfecta type I
    Davide Gatti
    Rheumatology Unit, Department of Medicine, University of Verona, Piazzale Stefani 1, 37126, Verona, Italy
    Calcif Tissue Int 93:448-52. 2013
    ..Our results open the possibility to develop TPD for the treatment of adult type I OI, but particularly for the lack of a control group, a properly designed controlled study is warranted...
  34. doi request reprint Relationship of focal erosions, bone mineral density, and parathyroid hormone in rheumatoid arthritis
    Maurizio Rossini
    Rheumatology Unit, Azienda Ospedaliera Universitaria Integrata, Piazzale Stefani 1, 37126 Verona, Italy
    J Rheumatol 38:997-1002. 2011
    ..To investigate the relationship among focal bone erosions and bone mineral density (BMD), 25(OH) vitamin D (25OHD), and parathyroid hormone (PTH) values in patients with rheumatoid arthritis (RA)...
  35. ncbi request reprint Fracture incidence and characterization in patients on osteoporosis treatment: the ICARO study
    Silvano Adami
    Rheumathology Department, University of Verona, Valeggio Sul Mincio Hospital VR, Verona, Italy
    J Bone Miner Res 21:1565-70. 2006
    ..9%/year of them. This incidence is considerably higher than that observed in randomized clinical trials, and it was significantly related to poor compliance and lack of supplementation with calcium and vitamin D...
  36. doi request reprint Acute phase response after zoledronic acid is associated with long-term effects on white blood cells
    Maurizio Rossini
    Rheumatology Section, Department of Medicine, University of Verona, Italy
    Calcif Tissue Int 93:249-52. 2013
    ..The mechanism leading to the observed decrease of circulating lymphocytes and eosinophils remains unclear, but our observation opens a new frontier for the understanding of the immunoeffects of N-BPs...
  37. doi request reprint Bisphosphonate treatment of postmenopausal osteoporosis is associated with a dose dependent increase in serum sclerostin
    Davide Gatti
    Rheumatology Unit, Department of Medicine, University of Verona, Italy
    Bone 50:739-42. 2012
    ..This might suggest that Wnt signaling may play a role in the coupling between resorption and formation...
  38. doi request reprint Long-term effects of neridronate and its discontinuation in patients with primary hyperparathyroidism
    Maurizio Rossini
    Rheumatology Unit, Department of Medicine, University of Verona, OCM Borgo Trento, P le Stefani 1, 37126, Verona, Italy
    Calcif Tissue Int 89:21-8. 2011
    ..The marked increases in serum PTH levels, particularly in subjects with low 25OHD levels, persist after treatment discontinuation and this raises the suspicion that this might reflect a worsening of PHPT...
  39. doi request reprint The co-occurrence of Hashimoto thyroiditis in primary Sjogren's syndrome defines a subset of patients with milder clinical phenotype
    Paola Caramaschi
    Rheumatology Unit, Department of Medicine, University of Verona, Verona, Italy
    Rheumatol Int 33:1271-5. 2013
    ..1-8.2 % of the cases, without reaching statistical significance. The association of HT in patients suffering from pSS defines a subset of patients with milder disease and normal C4 levels...
  40. doi request reprint The waning of teriparatide effect on bone formation markers in postmenopausal osteoporosis is associated with increasing serum levels of DKK1
    Davide Gatti
    University of Verona, Rheumatology Unit, Valeggio Hospital, Via Ospedale, Valeggio 37067, Verona, Italy
    J Clin Endocrinol Metab 96:1555-9. 2011
    ..TPD is thought to stimulate bone formation by down-regulating the expression of specific Wnt antagonists, such as of sclerostin and Dickkopf-1 (DKK1)...
  41. ncbi request reprint Intravenous neridronate in children with osteogenesis imperfecta: a randomized controlled study
    Davide Gatti
    Department of Rheumatology, University of Verona, Verona, Italy
    J Bone Miner Res 20:758-63. 2005
    ..These results are associated with a significant decrease in the risk of clinical fractures...
  42. ncbi request reprint Effect of low dose methotrexate on bone density in women with rheumatoid arthritis: results from a multicenter cross-sectional study
    Ombretta di Munno
    Rheumatology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy
    J Rheumatol 31:1305-9. 2004
    ..To analyze the influence of low dose methotrexate (MTX) on bone using data from a large multicenter, cross-sectional study on bone mineral density (BMD) in women with rheumatoid arthritis (RA)...
  43. ncbi request reprint Bone involvement and osteoporosis in mastocytosis
    Maurizio Rossini
    University of Verona, Policlinico Borgo Roma, Piazzale Scuro, 10, Verona 37134, Italy Electronic address
    Immunol Allergy Clin North Am 34:383-96. 2014
    ..The bone turnover markers indicate the involvement of complex bone metabolism in mastocytosis-related manifestations. Bisphosphonates represent the first-line treatment for osteoporosis-related mastocytosis. ..
  44. ncbi request reprint Epidemiology of primary hyperparathyroidism in Europe
    Silvano Adami
    Rheumatologic Unit, University of Verona, Italy
    J Bone Miner Res 17:N18-23. 2002
    ..quot; Other environmental, nutritional, or iatrogenic factors might influence the incidence of the disease, but the overall effect is unlikely to be relevant...
  45. pmc Profile of bazedoxifene/conjugated estrogens for the treatment of estrogen deficiency symptoms and osteoporosis in women at risk of fracture
    Maurizio Rossini
    Department of Medicine, Rheumatology Unit, University of Verona, Italy
    Drug Des Devel Ther 7:601-10. 2013
    ....
  46. ncbi request reprint Treatment of complex regional pain syndrome type I with neridronate: a randomized, double-blind, placebo-controlled study
    Massimo Varenna
    Rheumatology Unit, Ospedale G Pini, Milan, Italy
    Rheumatology (Oxford) 52:534-42. 2013
    ..The aim of this multi-centre, randomized, double-blind placebo-controlled trial was to test the efficacy of the amino-bisphosphonate neridronate in patients with CRP-I...
  47. doi request reprint Circulating γδ T cells and the risk of acute-phase response after zoledronic acid administration
    Maurizio Rossini
    Rheumatology Unit, Department of Medicine, University of Verona, Verona, Italy
    J Bone Miner Res 27:227-30. 2012
    ..In conclusion, the results of this study indicate that the number of circulating γδ T cells, together with age, are important determinant of the occurrence of APR after intravenous infusion of ZOL and possibly of any other N-BPs...
  48. doi request reprint Long-term effects of amino-bisphosphonates on circulating γδ T cells
    Maurizio Rossini
    Rheumatology Unit, Department of Medicine, University of Verona, Policlinico Borgo Roma, Piazzale Scuro, 10, 37134, Verona, Italy
    Calcif Tissue Int 91:395-9. 2012
    ..Other clinical implications of this sustained effect of N-BPs on immune-regulatory cells might be important...
  49. pmc Vitamin D deficiency in rheumatoid arthritis: prevalence, determinants and associations with disease activity and disability
    Maurizio Rossini
    Rheumatology Unit, University of Verona, Piazzale Stefani 1, 37124 Verona, Italy
    Arthritis Res Ther 12:R216. 2010
    ....
  50. doi request reprint Neridronic acid for the treatment of bone metabolic diseases
    Davide Gatti
    University of Verona, Rheumatology Unit, Ospedale di Valeggio, 37067 Valeggio, Verona, Italy
    Expert Opin Drug Metab Toxicol 5:1305-11. 2009
    ..This avoids all the limitations of oral bisphosphonates and may be offered for a home treatment with simple nursing assistance...
  51. doi request reprint Allergy and the bone: unexpected relationships
    Davide Gatti
    Rheumatologic Department, University of Verona, Verona, Italy
    Ann Allergy Asthma Immunol 107:202-6. 2011
    ..To examine the relationships between allergy and bone metabolism as represented by the effects of antihistamines and leukotriene modifiers on bone resorption and formation...
  52. ncbi request reprint Bone turnover markers in patients with osteogenesis imperfecta
    Vania Braga
    Rheumatology Unit, University of Verona, Valeggio S M, Italy
    Bone 34:1013-6. 2004
    ..These results provide a strong rational for the use of anti-resorbing agent in OI...
  53. ncbi request reprint The volumetric bone density and cortical thickness in adult patients affected by osteogenesis imperfecta
    Davide Gatti
    Riabilitazione Reumatologica, Universita di Verona, University Hospital Valeggio S M, Verona, Italy
    J Clin Densitom 6:173-7. 2003
    ..In conclusion, it appears that the most obvious defect in adults with OI is the inability to acquire an adequate thickness of the cortices of long bone and to achieve or maintain normal trabecular density...
  54. ncbi request reprint Relationship among VDR (BsmI and FokI), COLIA1, and CTR polymorphisms with bone mass, bone turnover markers, and sex hormones in men
    V Braga
    Rheumatology Unit, Valeggio S M, University of Verona, Italy
    Calcif Tissue Int 70:457-62. 2002
    ..The lower BMD in CC genotype is apparently associated in males with depressed bone formation and lower estradiol levels...
  55. doi request reprint Relationship between body composition and both cardiovascular risk factors and lung function in systemic sclerosis
    Paola Caramaschi
    Rheumatology Unit, University of Verona, Verona, Italy
    Clin Rheumatol 33:77-82. 2014
    ..Longitudinal studies are needed to evaluate if decrease of abdominal fat would improve lung function. ..
  56. doi request reprint Once-monthly oral ibandronate in postmenopausal osteoporosis: translation and updated review
    Maurizio Rossini
    Rheumatology Unit, University Hospital of Verona, Verona 37126, Italy
    Clin Ther 31:1497-510. 2009
    ..New drugs or treatment regimens that reduce the risk for osteoporotic fractures and make the treatment of osteoporosis more convenient and suitable for patients are needed...
  57. doi request reprint Densitometric threshold and vertebral fractures in heart transplant patients
    Luca Dalle Carbonare
    Department of Medicine, Clinic of Internal Medicine, Section D, University of Verona, Verona, Italy
    Transplantation 92:106-11. 2011
    ..The aim of our study was to evaluate osteoporosis and fracture prevalence, bone metabolism, and the effect of immunosuppressant agents on bone after heart transplantation...
  58. doi request reprint Bone mineral density, bone turnover markers and fractures in patients with indolent systemic mastocytosis
    Maurizio Rossini
    Rheumatology Section, Department of Medicine, University of Verona, Italy
    Bone 49:880-5. 2011
    ..We systematically assessed bone mineral density (BMD), bone turnover markers (BTM), and fractures in a large cohort of patients with Indolent Systemic Mastocytosis (ISM)...
  59. pmc Capacitively coupled electric field for pain relief in patients with vertebral fractures and chronic pain
    Maurizio Rossini
    Rheumatology Unit, Department of Biomedical and Surgical Sciences, University of Verona, OCM Borgo Trento, P Le Stefani, 1, 37126 Verona, Italy
    Clin Orthop Relat Res 468:735-40. 2010
    ..We interpret these findings as suggesting capacitive coupling electrical stimulation controls pain in some patients and reduces the use of NSAIDs...
  60. ncbi request reprint Relationship between leptin levels and bone mineral density in the elderly
    Elena Zoico
    Cattedra di Geriatria, Universita di Verona, Verona, Italy
    Clin Endocrinol (Oxf) 59:97-103. 2003
    ..To assess the relationship between circulating leptin levels, bone mineral content and density in the elderly...
  61. ncbi request reprint Effects of oral alendronate in elderly patients with osteoporosis and mild primary hyperparathyroidism
    M Rossini
    Riabilitazione Reumatologica, Ospedale di Valeggio, , Italy
    J Bone Miner Res 16:113-9. 2001
    ..These preliminary results may make alendronate a candidate as a supportive therapy in patients with mild PHPT who are unwilling or are unsuitable for surgery, and for whom osteoporosis is a reason of concern...
  62. ncbi request reprint Association of CTR and COLIA1 alleles with BMD values in peri- and postmenopausal women
    V Braga
    Department of Rheumatology, Valeggio S M, University of Verona, Verona, Italy
    Calcif Tissue Int 67:361-366. 2000
    ..These findings suggest an association between the COLIA1 gene polymorphism more with the age-related rate of bone loss than with peak bone mass, which apparently is somewhat affected by CTR gene polymorphism...
  63. doi request reprint Intra-articular clodronate for the treatment of knee osteoarthritis: dose ranging study vs hyaluronic acid
    Maurizio Rossini
    Rheumatology Unit, University of Verona, Verona, Italy
    Rheumatology (Oxford) 48:773-8. 2009
    ..In this Phase 2 randomized, partially blind clinical trial, we tested the efficacy of IA clodronate vs HA in patients with primary KOA...
  64. ncbi request reprint Intravenous neridronate in adults with osteogenesis imperfecta
    S Adami
    Rheumatologic Rehabilitation, University of Verona, Verona, Italy
    J Bone Miner Res 18:126-30. 2003
    ..Bisphosphonate therapy seems to provide clinical benefits, not only to children with OI, but also to adult patients...
  65. ncbi request reprint Prevalence and incidence of rheumatoid arthritis in Italy
    Maurizio Rossini
    Rheumatology Section, Department of Medicine, University of Verona, Policlinico GB Rossi, 37124, Verona, Italy
    Rheumatol Int 34:659-64. 2014
    ..With advancing age, the female/male ratio declines to about one. ..
  66. doi request reprint Involvement of WNT/β-catenin signaling in the treatment of osteoporosis
    Maurizio Rossini
    Department of Medicine, Rheumatology Section, Policlinico Borgo Roma, University of Verona, Piazzale Scuro, 10, 37134, Verona, Italy
    Calcif Tissue Int 93:121-32. 2013
    ..Inactivating monoclonal antibodies against SOST appears to be the most attractive strategy because SOST is the only component of the WNT pathway expressed almost exclusively by osteocytes. ..
  67. ncbi request reprint Denosumab treatment in postmenopausal women with osteoporosis does not interfere with fracture-healing: results from the FREEDOM trial
    Silvano Adami
    Faculty of Medicine and Surgery, University of Verona, P le Scuro 10, 37134, Verona, Italy
    J Bone Joint Surg Am 94:2113-9. 2012
    ....
  68. doi request reprint The early psoriatic arthritis screening questionnaire: a simple and fast method for the identification of arthritis in patients with psoriasis
    Ilaria Tinazzi
    Unit of Rheumatology, University of Verona, P le Scuro, 1 37134 Verona, Italy
    Rheumatology (Oxford) 51:2058-63. 2012
    ..This study aimed to develop a rapid and robust screening questionnaire for predicting PsA in patients with psoriasis referred to a specialized joint dermatology-rheumatology combined clinic...
  69. ncbi request reprint Baseline characteristics of the population enrolled in the Italian Observational Study on Severe Osteoporosis (ISSO)
    S Adami
    Unità Riabilitazione Reumatologica Osseo Articolare, Ospedale Maggiore Borgo Trento, Verona, Italy
    Clin Exp Rheumatol 29:477-84. 2011
    ....
  70. ncbi request reprint Intravenous intermittent neridronate in the treatment of postmenopausal osteoporosis
    V Braga
    Rheumatology Unit, Valeggio S M, University of Verona, Italy
    Bone 33:342-5. 2003
    ..Treatment of postmenopausal osteoporosis with 50 mg i.v. neridronate bimonthly results in clinically relevant increases in BMD, among the largest so far observed with any other bisphosphonate...
  71. ncbi request reprint Alendronate for the treatment of osteoporosis in men
    S Adami
    Riabilitazione Reumatologica, , Ospedale di Valeggio, Italy
    Calcif Tissue Int 69:239-41. 2001
    ..By combining the results of all these trials, bisphosphonate efficacy in terms of both BMD changes and fracture incidence appears to be moderate in premenopausal women but quite obvious and comparable in males and postmenopausal women...
  72. doi request reprint Osteoporosis treatment: why ibandronic acid?
    Maurizio Rossini
    University of Verona, Department of Medicine, Rheumatology Section, Policlinico Borgo Roma, Piazzale Scuro, 10 37134, Verona, Italy
    Expert Opin Pharmacother 14:1371-81. 2013
    ..In this article, we have summarized the specific evidence on ibandronic acid (or ibandronate) efficacy, tolerability, and feasibility acquired from trials and clinical use...
  73. pmc Clinical development of neridronate: potential for new applications
    Davide Gatti
    Rheumatology Unit, Department of Medicine, University of Verona, Verona, Italy
    Ther Clin Risk Manag 9:139-47. 2013
    ..We will focus in particular on the latest evidence of the effect of neridronate on treatment of complex regional pain syndrome type I...
  74. ncbi request reprint [Improvements in the management of rheumatic patients from vertebral image obtained through dual-energy X-ray absorptiometry]
    M Rossini
    Cattedra di Reumatologia, Universita degli Studi di Verona, Valeggio, Italia
    Reumatismo 58:253-60. 2006
    ..MXA, despite its intrinsic limitations, when carried out by trained personnel may provide substantial improvements in the management (diagnosis and follow-up) of rheumatic patients...
  75. ncbi request reprint Prevalence and correlates of vertebral fractures in adults with cystic fibrosis
    M Rossini
    Rheumatology Unit, Osteoporosis Center, University of Verona, 37122, Verona, Italy
    Bone 35:771-6. 2004
    ..Osteoporosis associated with cystic fibrosis (CF) is becoming increasingly important as the life expectancy of patients continues to increase...
  76. ncbi request reprint Radial bending breaking resistance derived by densitometric evaluation predicts femoral neck fracture
    D Gatti
    Riabilitazione Reumatologica, University Hospital Valeggio S/M, Verona, Italy
    Osteoporos Int 12:864-9. 2001
    ..They also give additional support to the view that bone geometry, particularly for compact skeletal segments, is a determinant of its strength at least as important as bone density...
  77. ncbi request reprint Short-term intravenous therapy with Neridronate in Paget's disease
    S Adami
    Department of Rheumatology, Valeggio S M, University of Verona, Italy
    Clin Exp Rheumatol 20:55-8. 2002
    ..To describe the effects of two consecutive intravenous infusions of aminohexane bisphosphonate (Neridronate) in patients with active Paget's disease of bone...
  78. ncbi request reprint Quantitative ultrasound in adults with cystic fibrosis: correlation with bone mineral density and risk of vertebral fractures
    M Rossini
    Rheumatology Unit, University of Verona, Azienda Ospedalieta, Verona, Italy
    Calcif Tissue Int 80:44-9. 2007
    ....
  79. ncbi request reprint Relation between adiponectin and bone mineral density in elderly post-menopausal women: role of body composition, leptin, insulin resistance, and dehydroepiandrosterone sulfate
    E Zoico
    Department of Geriatric Medicine, University of Verona, Verona, Italy
    J Endocrinol Invest 31:297-302. 2008
    ..The aim of this study was to test the relationship between adiponectin, leptin, and bone mineral density (BMD), independently of body composition, insulin resistance, and other factors known to affect bone metabolism...
  80. ncbi request reprint [Risk factors for hip fracture in elderly persons]
    M Rossini
    Centro Regione Veneto Specializzato per l Osteoporosi, U O Reumatologia, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italia
    Reumatismo 62:273-82. 2010
    ..The aim of this observational study, promoted by the Health Authorities of the Regione Veneto (Italy), is to assess the prevalence of the most relevant environmental and individual risk factors in subjects with a recent hip fracture...
  81. ncbi request reprint [How much does an antiinflammatory treatment cost?]
    D Gatti
    Unita di Reumatologia, Dipartimento di Medicina, Universita di Verona, Italia
    Reumatismo 62:248-52. 2010
    ..In conclusion the pharmacoeconomic analysis of an antinflammatory therapy cannot be based only on safety issues but also on efficacy evaluation that is the main effect we ask to these drugs...
  82. doi request reprint Digital amputation in systemic sclerosis: prevalence and clinical associations. A retrospective longitudinal study
    Paola Caramaschi
    Unita di Reumatologia, Policlinico G B Rossi, Piazzale Scuro, 37134 Verona, Italy
    J Rheumatol 39:1648-53. 2012
    ..To evaluate the prevalence of digital necrosis requiring surgical amputation in a single-center group of patients with systemic sclerosis (SSc) and to compare the characteristics of patients with and those without this severe complication...
  83. pmc Appropriate use of anabolic treatment for severe osteoporosis
    Silvano Adami
    Rheumatology Department, University of Verona, Verona, Italy
    Clin Cases Miner Bone Metab 7:114-22. 2010
    ....
  84. ncbi request reprint Drug-induced morphea: report of a case induced by balicatib and review of the literature
    Anna Peroni
    Department of Biomedical and Surgical Sciences, Section of Dermatology and Venereology, University of Verona, Verona, Italy
    J Am Acad Dermatol 59:125-9. 2008
    ..Drug withdrawal determined complete remission in only a few patients. Different drug classes have been implicated. Some of these, including balicatib, alter directly connective tissue metabolism...
  85. ncbi request reprint Determinants of adherence to osteoporosis treatment in clinical practice
    M Rossini
    Rheumatology Unit, University of Verona, Verona, and Rheumatology Unit, Ospedale Le Colletta, Genova, Italy
    Osteoporos Int 17:914-21. 2006
    ..This problem is apparently very common for osteoporosis treatment but the causes of discontinuation and low compliance are complex and poorly defined...
  86. ncbi request reprint [Rational and results of weekly treatment with calcidiol in postmenopausal and senile osteoporosis]
    M Rossini
    Unita di Reumatologia, Dipartimento di Scienze, Biomediche e Chirurgiche, Universita degli Studi di Verona, Verona, Italy
    Minerva Med 98:53-68. 2007
    ..The weekly dose of calcidiol may be adapted to individual needs, i.e 4,000 to 6,000 IU (or 20-30 drops) according to age or risk factors for vitamin D deficiency...
  87. pmc Evidence of sustained vertebral and nonvertebral antifracture efficacy with ibandronate therapy: a systematic review
    Silvano Adami
    Rheumatology Unit, University of Verona, Verona, Italy
    Ther Adv Musculoskelet Dis 3:67-79. 2011
    ..The antifracture efficacy of ibandronate at vertebral and nonvertebral sites was assessed...
  88. pmc The initiative on hip fractures of the Veneto Region
    Maurizio Rossini
    Osteoporosis Centers, Veneto Region, Italy, Integrated University Hospital of Verona, Verona, Italy
    Clin Cases Miner Bone Metab 9:45-9. 2012
    ..to assess the prevalence of the most relevant environmental and individual risk factors in subjects with a recent hip fracture was the aim of this observational study promoted by the Health Authorities of the Regione Veneto (Italy)...
  89. ncbi request reprint Coxibs: a significant therapeutic opportunity
    Davide Gatti
    Rheumatology Unit, Department of Medicine, University of Verona, Italy
    Acta Biomed 81:217-24. 2010
    ..In terms of cardiovascular risk their efficacy is associated to a similar safety profile as conventional NSAIDs, whereas the gastrointestinal risk related to coxibs seems to be significantly lesser...
  90. ncbi request reprint [Vitamin D and fractures: a systematic review]
    O Viapiana
    Riabilitazione Reumatologica, Universita di Verona, Ospedale Valeggio sul Mincio, Verona, Italia
    Reumatismo 59:15-9. 2007
    ..This analysis permits to confirm that vitamin D treatment can be extremely cost-effective when given to people at high risk of deficiency. An acceptable compliance is obviously of critical importance...
  91. ncbi request reprint Interferential and horizontal therapies in chronic low back pain due to multiple vertebral fractures: a randomized, double blind, clinical study
    A Zambito
    Rheumatologic Rehabilitation, University of Verona, Verona, Italy
    Osteoporos Int 18:1541-5. 2007
    ..In a randomized placebo-controlled clinical trial, we have shown that both interferential currents and horizontal therapy are more effective than placebo for functional...
  92. ncbi request reprint Interferential and horizontal therapies in chronic low back pain: a randomized, double blind, clinical study
    A Zambito
    Rheumatologic Rehabilitation, University of Verona, Italy
    Clin Exp Rheumatol 24:534-9. 2006
    ..Chronic Low Back Pain (CLBP) is one of the most frequent medical problems. Electrical nerve stimulation is frequently used but its efficacy remains controversial...
  93. ncbi request reprint [Use of nonsteroidal anti-inflammatory drugs in patients with vertebral osteoporotic fractures]
    M Rossini
    Gruppo di Studio Osteoposori e Fans Cattedra di Reumatologia, Universita di Verona, Verona, Italia
    Reumatismo 54:340-3. 2002
    ..The aim of the study was to assess the use of Non Steroidal Anti-Inflammatory Drugs (NSAIDs) in patients with a history of osteoporotic vertebral fractures...
  94. ncbi request reprint Double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia patients
    M Rossini
    Rheumatology Unit, University of Verona, Italy
    Clin Exp Rheumatol 25:182-8. 2007
    ..In this multicenter randomized clinical trial we evaluated the efficacy of acetyl L-carnitine (LAC) in patients with overt FMS...
  95. ncbi request reprint Similar proportions of women lose bone mineral density with raloxifene or alendronate treatment
    Jonathan D Adachi
    St Joseph s Hospital, McMaster University, Hamilton, Ontario, Canada
    J Clin Densitom 8:273-7. 2005
    ..In conclusion, similar proportions of women did not respond to raloxifene or alendronate therapy, as measured by changes in lumbar spine or femoral neck BMD, when precision error was taken into account...
  96. ncbi request reprint Efficacy and tolerability of intravenous ibandronate injections in postmenopausal osteoporosis: 2-year results from the DIVA study
    John A Eisman
    Garvan Institute of Medical Research, St Vincent s Campus and University of New South Wales, Sydney, Australia
    J Rheumatol 35:488-97. 2008
    ..We report the effects on lumbar spine and proximal femur bone mineral density (BMD) and bone resorption markers over 2 years...
  97. ncbi request reprint Influence of two different GH dosage regimens on final height, bone geometry and bone strength in GH-deficient children
    Giorgio Radetti
    Department of Paediatrics, Regional Hospital of Bolzano, Italy
    Eur J Endocrinol 154:479-82. 2006
    ..The aim was to investigate the effects of two different GH dosage regimens on growth, bone geometry and bone strength...
  98. ncbi request reprint Quality of life in osteoporotic women with inadequate clinical response to antiresorptive drugs: results from the ICARO study
    Mario Barbagallo
    Division of Geriatrics, Department of Internal Medicine and Emergent Pathologies, University of Palermo, Palermo, Italy
    Aging Clin Exp Res 19:24-7. 2007
    ..The aim of the present study was to evaluate the impact of the clinical response to treatment on the health-related quality of life in women with postmenopausal osteoporosis...
  99. ncbi request reprint Upper gastrointestinal tract safety of risedronate: a pooled analysis of 9 clinical trials
    Hugh Taggart
    Department of Health Care for the Elderly, Belfast City Hospital, Belfast, Northern Ireland, United Kingdom
    Mayo Clin Proc 77:262-70. 2002
    ..The results of this extensive evaluation indicate that daily treatment with 5 mg of risedronate sodium is not associated with an increased frequency of adverse GI tract effects, even among patients at high risk for these events...
  100. ncbi request reprint Intravenous ibandronate injections in postmenopausal women with osteoporosis: one-year results from the dosing intravenous administration study
    Pierre D Delmas
    Université Claude Bernard Lyon 1 and INSERM Research Unit 403, Lyon, France
    Arthritis Rheum 54:1838-46. 2006
    ..The aim of this study was to identify the optimal intravenous dosing regimen for ibandronate in postmenopausal women with osteoporosis...
  101. ncbi request reprint A new concept for bisphosphonate therapy: a rationale for the development of monthly oral dosing of ibandronate
    Jean Yves Reginster
    Unite d Exploration du Metabolisme de l Os et du Cartilage, CHU Centre Ville, Liege, Belgium
    Osteoporos Int 17:159-66. 2006
    ..Greater convenience and tolerability may enhance the therapy adherence and, hence, improve long-term therapeutic outcomes in PMO...