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| Unit of Pneumology and AllergologySummaryOrganization: Unit of Pneumology and Allergology Country: Italy Top Publications
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Publications
A case of pulmonary tuberculosis presenting as diffuse alveolar haemorrhage: is there a role for anticardiolipin antibodies?Almerico Marruchella
Respiratory Endoscopy Unit, National Institute for Infectious Diseases L, Spallanzani, Via Portuense 292, 00149 Rome, Italy
BMC Infect Dis 10:33. 2010..Diffuse alveolar haemorrhage (DAH) has been rarely reported in association with pulmonary infections...
Adjustable maintenance dosing with budesonide/formoterol in a single inhaler provides effective asthma symptom control at a lower dose than fixed maintenance dosingG W Canonica
Clinica di Malattie dell Apparato Respiratorio e Allergologia, DIMI, Universita degli Studi di Genova, Padiglione Maragliano, Largo Rosanna Benzi, 10 16132 Genova, Italy
Pulm Pharmacol Ther 17:239-47. 2004..In conclusion, adjustable maintenance dosing with budesonide/formoterol effectively controls asthma at a reduced drug load with lower costs than fixed maintenance dosing...
Salmeterol/fluticasone propionate in a Single Inhaler Device versus theophylline+fluticasone propionate in patients with COPDMario Cazzola
Respiratory Medicine and Allergology Unit, A Cardarelli Hospital, Via del Parco Margherita 24, 80121 Naples, Italy
Pulm Pharmacol Ther 17:141-5. 2004....
Onset of action of formoterol/budesonide in single inhaler vs. formoterol in patients with COPDM Cazzola
Department of Pneumology, Unit of Pneumology and Allergology, Antonio Cardarelli Hospital, Milan, Italy
Pulm Pharmacol Ther 17:121-5. 2004..This study indicates that the addition of budesonide influences the fast onset of action of formoterol, but does not induce systemic effects, in patients with stable COPD...
[Clinical aspects of chronic obstructive pulmonary disease]Pierluigi Paggiaro
Dipartimento Cardio Toracico, Sezione di Pneumologia, Universita degli Studi, Pisa
Ann Ist Super Sanita 39:519-28. 2003..Accurate definition of the heterogeneity of chronic obstructive pulmonary disease can be useful in the prognosis and management of the disease...
Alternative and/or integrative therapies for pneumonia under developmentMario Cazzola
A Cardarelli Hospital, Department of Respiratory Medicine, Unit of Pneumology and Allergology, Naples, Italy
Curr Opin Pulm Med 10:204-10. 2004..Interfering with bacterial adhesion, inhibiting, neutralizing and clearing endotoxin, and administering cytokines as immunoadjuvants are the most promising alternative or integrative treatments for pneumonia that are under development...
Comparative effects of a two-week treatment with nebivolol and nifedipine in hypertensive patients suffering from COPDMario Cazzola
Unit of Pneumology and Allergology, Department of Pneumology, A Cardarelli Hospital, Naples, Italy
Respiration 71:159-64. 2004....
Macrolide and occult infection in asthmaMario Cazzola
A Cardarelli Hospital, Department of Respiratory Medicine, Unit of Pneumology and Allergology, Naples, Italy
Curr Opin Pulm Med 10:7-14. 2004..These discrepancies highlight the need to define the role, if any, of antimicrobials that are active against atypical pathogens, mainly macrolides, but also tetracyclines and fluoroquinolones, in the treatment of asthma...
Shuttle walking test and 6-minute walking test induce a similar cardiorespiratory performance in patients recovering from an acute exacerbation of chronic obstructive pulmonary diseaseB Vagaggini
Cardio Thoracic Department, Pneumology Section, University of Pisa, Italy
Respiration 70:579-84. 2003....
Novel approaches to the treatment of pneumoniaMario Cazzola
Cardarelli Hospital, Department of Respiratory Medicine, Unit of Pneumology and Allergology, Via del Parco Margherita 24, 80121 Napoli, Italy
Trends Pharmacol Sci 24:306-14. 2003..The challenge is to optimize and develop these agents to provide novel approaches to the treatment of pneumonia in hospitalized patients...
Novelties in the field of antimicrobial compounds for the treatment of lower respiratory tract infectionsMario Cazzola
Department of Respiratory Medicine, Unit of Pneumology and Allergology, A Cardarelli Hospital, Via del Parco Margherita 24, 80121 Naples, Italy
Pulm Pharmacol Ther 16:131-45. 2003..Obviously, these antibiotics must be reserved only to cases of documented ineffectiveness of the common antimicrobial agents...
A single high dose of formoterol is as effective as the same dose administered in a cumulative manner in patients with acute exacerbation of COPDM Cazzola
Dipartimento di Medicina Respiratoria, Azienda Ospedaliera di Rilevanza Nazionale A Cardarelli, Unità Complessa di Pneumologia e Allergologia, Napoli, Italy
Respir Med 97:458-62. 2003..Also they did not influence SpO2. This study indicates that a single high dose offormoterol is as effective as the same dose administered in a cumulative manner in patients with acute exacerbation of COPD...
Tuberculin reactivity in adult BCG-vaccinated subjects: a cross-sectional studyM Bugiani
Pneumology Unit, Consorzio Provinciale Antitubercolare, Azienda Sanitaria Locale 4, Piedmont, Turin, Italy
Int J Tuberc Lung Dis 7:320-6. 2003..The skin reaction to the vaccination interferes with the management of individuals who may be infected with Mycobacterium tuberculosis...
Bronchodilator response to formoterol Turbuhaler in patients with COPD under regular treatment with formoterol TurbuhalerMario Cazzola
Department of Respiratory Medicine, Unit of Pneumology and Allergology, A Cardarelli Hospital, Second University of Naples, Via del Parco Margherita 24, 80121 Naples, Italy
Pulm Pharmacol Ther 16:105-9. 2003..001) from 2-h levels. These results show that dose-dependent bronchodilatation of formoterol is maintained despite regular treatment...
The functional impact of adding salmeterol and tiotropium in patients with stable COPDM Cazzola
Department of Respiratory Medicine, Antonio Cardarelli Hospital, Via del Parco Margherita 24, Napoli 80121, Italy
Respir Med 98:1214-21. 2004....
Rehabilitation of COPD patients: which training modalityE Clini
Fondazione Villa Pineta, Dpt of Pulmonary Rehabilitation, Pavullo MO, Italy
Monaldi Arch Chest Dis 61:167-73. 2004..In conclusion, both modalities are effective and useful for COPD patients. However, whether resistance training should be administered to all COPD and which is the optimal length of strength training still needs to be elucidated...
Indoor particulate matter measurement as a tool in the process of the implementation of smoke-free hospitalsS Nardini
Vittorio Veneto General Hospital, Italy
Monaldi Arch Chest Dis 61:183-92. 2004..Here the first experience of measuring PM in hospitals for monitoring ETS and certificating smoke-free health premises, is described...
Safety of long-acting beta2-agonists in the treatment of asthmaMario Cazzola
Unit of Respiratory Diseases, Department of Internal Medicine, University of Rome Tor Vergata, Via Montpellier 1, Rome, Italy
Ther Adv Respir Dis 1:35-46. 2007..Patients with asthma should be initiated and maintained on sufficiently high doses of ICSs and only patients whose asthma cannot be controlled should receive additional LABAs on a regular basis...
A recombinant humanized anti-IgE monoclonal antibody (omalizumab) in the therapy of moderate-to-severe allergic asthmaGennaro D'Amato
Division of Respiratory and Allergic Diseases, Department of Respiratory Diseases, High Speciality Hospital A Cardarelli, Naples, Italy
Recent Pat Inflamm Allergy Drug Discov 1:225-31. 2007..In conclusion omalizumab represents a really new approach to the treatment of atopic asthma and may fulfil an important need in patients with moderate-to-severe asthma...
Acute effects of higher than standard doses of salbutamol and ipratropium on tiotropium-induced bronchodilation in patients with stable COPDMario Cazzola
Unit of Respiratory Diseases, Department of Internal Medicine, University of Rome Tor Vergata, Rome, Italy
Pulm Pharmacol Ther 22:177-82. 2009....
Effects of climate change on environmental factors in respiratory allergic diseasesG D'Amato
Division of Respiratory and Allergic Diseases, Department of Chest Diseases, High Speciality Hospital A Cardarelli, Napoli, Italy
Clin Exp Allergy 38:1264-74. 2008....
The role of combination therapy with corticosteroids and long-acting beta2-agonists in the prevention of exacerbations in COPDMario Cazzola
Antonio Cardarelli Hospital, Department of Respiratory Medicine, Unit of Pneumology and Allergology, Naples, Italy
Int J Chron Obstruct Pulmon Dis 1:345-54. 2006..However, when patients with more severe COPD were studied using a combination of budesonide and formoterol, a clear improvement was seen in the overall exacerbation rates compared with the use of a long-acting beta2-agonist alone...
Reference values of Forced Expiratory Volumes and pulmonary flows in 3-6 year children: a cross-sectional studyPavilio Piccioni
SC Pneumologia CPA ASL 4 Torino Strada dell arrivore 25 A 10154 Torino, Italy
Respir Res 8:14. 2007..The aims of this study were to verify the feasibility of respiratory function tests and to assess their validity in the diagnosis of respiratory disorders in young children...
[Pressure support ventilation in neonatal age: lights and shadows]Alessandra Serra
Terapia Intensiva e Patologia Neonatale, IRCCS Policlinico San Matteo, Pavia
Pediatr Med Chir 27:13-8. 2005..In conclusion, PSV represents a modality of ventilation that ca be used in stable newborns, while its use is contraindicates in critically newborns with abnormal central respiratory drive...
Doppler echocardiographic assessment of the effects of inhaled long-acting beta2-agonists on pulmonary artery pressure in COPD patientsMario Cazzola
Unit of Pneumology and Allergology, A Cardarelli Hospital, Via del Parco Margherita 24, 80121 Napoli, Italy
Pulm Pharmacol Ther 20:258-64. 2007..A direct vasodilatation due to the activation of beta-adrenoceptors that are present in pulmonary vessels is a likely mechanism of their action in inducing the decrease in sPAP...
Pharmacodynamics of levofloxacin in patients with acute exacerbation of chronic bronchitisMario Cazzola
Department of Pneumology, Unit of Pneumology and Allergology, A Cardarelli Hospital, Naples, Italy
Chest 128:2093-8. 2005....
Environmental risk factors and allergic bronchial asthmaG D'Amato
Department of Chest Diseases, Division of Pneumology and Allergology, High Speciality Hospital A Cardarelli, Via Rione Sirignano 10, 80121 Naples, Italy
Clin Exp Allergy 35:1113-24. 2005..After rupture by thunderstorm, pollen grains may release part of their cytoplasmic content, including inhalable, allergen-carrying paucimicronic particles...
Treatment of acute exacerbation of severe-to-very severe COPD with azithromycin in patients vaccinated against Streptococcus pneumoniaeMario Cazzola
Department of Pneumology, Unit of Pneumology and Allergology, A Cardarelli Hospital, Naples, Italy
Respir Med 99:663-9. 2005..This finding allows the use of antibiotics such as azithromycin, which, otherwise, should be avoided because of resistances...
Bronchodilator response to formoterol after regular tiotropium or to tiotropium after regular formoterol in COPD patientsMario Cazzola
Antonio Cardarelli Hospital, Department of Respiratory Medicine, Unit of Pneumology and Allergology, Naples, Italy
Respir Med 99:524-8. 2005..Differences between the two treatments were not statistically significant (P>0.05). The addition of second different long-acting bronchodilator to a regularly administered long-acting bronchodilator seems to be to patient's advantage...
Novel approaches to the treatment of bacterial lower respiratory tract infections: introductionMario Cazzola
Unit of Pneumology and Allergology, Department of Respiratory Medicine, A. Cardarelli Hospital, Naples, Italy
Respiration 72:7-8. 2005
The asthma-rhinitis association: between the clinical hypothesis and the scientific theoryGiovanni Passalacqua
Allergy and Respiratory Diseases--Department of Internal Medicine, University of Genoa, Padiglione Maragliano, Largo R. Benzi, 10, 16132 Genoa, Italy
Curr Allergy Asthma Rep 3:191-3. 2003
The burden of COPD in Italy: results from the Confronting COPD surveyR Dal Negro
Divisione Pneumologia, Ospedale Orlandi, Bussolengo, Verona, Italy
Respir Med 97:S43-50. 2003....
Formoterol Turbuhaler for as-needed therapy in patients with mild acute exacerbations of COPDM Cazzola
Ospedale A Cardarelli, Dipartimento di Pneumologia, U O di Pneumologia e Allergologia, Napoli, Italy
Respir Med 95:917-21. 2001..Results of this study suggest the use of higher than customary dose of formoterol for as-needed therapy to provide rapid relief of bronchospasm in patients suffering from acute exacerbations of partially reversible COPD...
In-hospital short-term training program for patients with chronic airway obstructionE Clini
Salvatore Maugeri Foundation IRCCS, Lung Function Unit, Scientific Institute of Gussago, Italy
Chest 120:1500-5. 2001..To compare the functional benefits and relative costs of administering an intense short-term inpatient vs a longer outpatient pulmonary rehabilitation program (PRP) for patients with chronic airway obstruction (CAO)...
Comparison of the bronchodilating effect of salmeterol and zafirlukast in combination with that of their use as single treatments in asthma and chronic obstructive pulmonary diseaseM Cazzola
Division of Pneumology and Allergology and Unit of Respiratory Clinical Pharmacology, A Cardarelli Hospital, Naples, Italy
Respiration 68:452-9. 2001..It has been suggested that the effect of a beta2-agonist is additive with that of a cysteinyl leukotriene 1 receptor antagonist...
Advances in the research and development of chemotherapeutic agents for respiratory tract bacterial infectionsM Cazzola
A Cardarelli Hospital, Department of Respiratory Medicine, Naples, Italy
Pulm Pharmacol Ther 14:367-81. 2001....
Pulmonary disposition of lomefloxacin in patients with acute exacerbation of chronic obstructive pulmonary disease. A multiple-dose studyM Cazzola
Divisione di Pneumologia ed Allergologia e Settore di Farmacologia Clinica Respiratoria, AORN A Cardarelli, Napoli, Italy
J Chemother 13:407-12. 2001....
The role of outdoor air pollution and climatic changes on the rising trends in respiratory allergyG D'Amato
Division of Pneumology and Allergology, Azienda Ospedaliera ad Alta Specialità A Cardarelli, Napoli, Italy
Respir Med 95:606-11. 2001..Several factors influence this interaction, including type of air pollutants, plant species, nutrient balance, climatic factors, degree of airway sensitization and hyperresponsiveness of exposed subjects...
Methylprednisolone suleptanate Pharmacia CorpP Paggiaro
University of Pisa Fisiopatologia Respiratoria Ospedale di Cisanello via Paradisa 2 Pisa 56100, Italy
Curr Opin Investig Drugs 1:97-103. 2000..Preclinical studies are also taking place for the potential treatment of spinal cord injury [344254]. In April 2000, Morgan Stanley Dean Witter estimated sales would be US $281 million in 2003, rising to $277 million in 2004 [375906]...
Onset of action of single doses of formoterol administered via Turbuhaler in patients with stable COPDM Cazzola
Division of Pneumology and Allergology and Unit of Respiratory Clinical Pharmacology, A Cardarelli Hospital, Naples, Italy
Pulm Pharmacol Ther 14:41-5. 2001..Again, there was no significant difference (P= 0.817) between the four active treatments. Formoterol Turbuhaler 12 microg and 24 microg caused bronchodilation as rapidly as salbutamol 400 microg and 800 microg given via pMDI...
Bacterial agents of lower respiratory tract infections (LRTIs), beta-lactamase production, and resistance to antibiotics in elderly people. DEDALO Study GroupC M Sanguinetti
U O di Pneumologia, Presidio Ospedaliero Unificato ASL 7 Ancona, Via Leopardi, 15 60027 Osimo, Ancona, Italy
Int J Antimicrob Agents 16:467-71. 2000..These data along with the clinical presentation, severity of infection, and epidemiological knowledge, might represent a guide for the choice of empiric antimicrobial treatment...
Additive effects of salmeterol and fluticasone or theophylline in COPDM Cazzola
A Cardarelli Hospital, Division of Pneumology and Allergology and Respiratory Clinical Pharmacology Unit, Naples, Italy
Chest 118:1576-81. 2000..ss(2)-Agonists and corticosteroids or theophylline can interact to produce beneficial effects on airway function in asthma, but this has not been established in COPD...
Influence of higher than conventional doses of oxitropium bromide on formoterol-induced bronchodilation in COPDM Cazzola
A Cardarelli Hospital, Division of Pneumology and Allergology, Naples, Italy
Respir Med 93:909-11. 1999..In any case, formoterol 24 microg alone seems sufficient to achieve the same bronchodilation induced by oxitropium 600 microg alone in most patients...
Oral and sublingual immunotherapy: general aspects and critical considerationsG Passalacqua
Department of Allergy and Respiratory Diseases, Genoa University, Italy
Wien Med Wochenschr 149:433-7. 1999..Furthermore, SLIT reduces time and money expenses usually required by SIT since it is self-administered...
Acute respiratory failure in patients with severe community-acquired pneumonia. A prospective randomized evaluation of noninvasive ventilationM Confalonieri
Unità Operativa di Pneumologia, Ospedale Civile di Piacenza, Piacenza, Italy
Am J Respir Crit Care Med 160:1585-91. 1999..A 2-mo survival advantage was seen in patients with COPD...
Impact of rhinitis on airway inflammation: biological and therapeutic implicationsG Passalacqua
Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Italy
Respir Res 2:320-3. 2001..We discuss some of the recent observations on the nose-lung interaction and some of the novel therapeutic approaches used to treat rhinitis and asthma that arise from this...
Iron lung vs mask ventilation in the treatment of acute on chronic respiratory failure in COPD patients: a multicenter studyAntonio Corrado
Respiratory Intensive Care Unit, Azienda Ospedaliera di Careggi Firenze, Florence, Italy
Chest 121:189-95. 2002..Evaluation of the effectiveness of negative-pressure ventilation (NPV) with the use of the iron lung vs noninvasive positive-pressure ventilation (NIPPV) in the treatment of COPD patients with acute on chronic respiratory failure...
The pharmacologic treatment of uncomplicated arterial hypertension in patients with airway dysfunctionMario Cazzola
Dipartimento di Pneumologia, Unità Operativa Complessa di Pneumologia ed Allergologia, Ospedale A Cardarelli, Napoli, Italy
Chest 121:230-41. 2002..For patients who are unresponsive to the aforementioned drugs, AT(1) receptor antagonists, newer beta(1)-adrenoceptor-blocking agents with ancillary properties (eg, celiprolol or nebivolol), and/or vasodilators can be considered...
Have guidelines for the management of community-acquired pneumonia influenced outcomes?M Cazzola
A. Cardarelli Hospital, Department of Respiratory Medicine, Unit of Pneumology and Allergology, Naples, Italy
Respir Med 97:205-11. 2003
Respiratory allergic diseases induced by outdoor air pollution in urban areasG D'Amato
Division of Pneumology and Allergology, Department of Chest Diseases, Azienda Ospedaliera ad Alta Specialità A Cardarelli, 80121 Napoli, Italy
Monaldi Arch Chest Dis 57:161-3. 2002..However, air pollution and climatic changes may also have an indirect effect on the allergic response by influencing quantitatively and qualitatively the pollen production of allergenic plants...
Ozone exposure increases eosinophilic airway response induced by previous allergen challengeBarbara Vagaggini
Cardiothoracic Department, Respiratory Pathophysiology Unit, University of Pisa, Pisa, Italy
Am J Respir Crit Care Med 166:1073-7. 2002..This observation may help explain the synergistic effect of air pollution and allergen exposure in the exacerbation of asthma...
Sputum inductionP L Paggiaro
Cardiothoracic Dept, Cisanello Hospital, Pisa, Italy
Eur Respir J Suppl 37:3s-8s. 2002
Outdoor air pollution, climatic changes and allergic bronchial asthmaG D'Amato
Division of Pneumology and Allergology, Azienda Ospedaliera ad Alta Specialità A Cardarelli, Napoli, Italy
Eur Respir J 20:763-76. 2002..As a consequence, an enhanced immunoglobulin E-mediated response to aeroallergens and enhanced airway inflammation favoured by air pollution could account for the increasing prevalence of allergic respiratory diseases in urban areas...
Treating atopic asthma with the anti-IgE monoclonal antibodyG D'Amato
Divisione di Malattie Respiratorie e Allergiche, Azienda Ospedaliera ad Alta Specialità di Rilievo Nazionale A Cardarelli, Napoli
Monaldi Arch Chest Dis 57:117-9. 2002....
Negative-pressure ventilation: is there still a role?A Corrado
Respiratory Intensive Care Unit, Azienda Ospedaliera Careggi, Firenze, Italy
Eur Respir J 20:187-97. 2002..This review is divided into two parts: the first is concerned with the use of negative-pressure ventilation in the short term, and the second with its use in the long term...
Addition of an extra dose of salmeterol Diskus to conventional dose of salmeterol Diskus in patients with COPDM Cazzola
Department of Respiratory Medicine, A Cardarelli Hospital, Naples, Italy
Respir Med 96:439-43. 2002....
Formoterol as dry powder oral inhalation compared with salbutamol metered-dose inhaler in acute exacerbations of chronic obstructive pulmonary diseaseM Cazzola
Department of Respiratory Medicine, A Cardarelli Hospital, Naples, Italy
Clin Ther 24:595-604. 2002....
Smoking cessation as a therapeutic and preventive intervention: a meeting reportS Nardini
Pulmonary and TB Unit, General Hospital, Vittorio Veneto, TV, Italy
Monaldi Arch Chest Dis 56:540-4. 2001..Obviously, smoking cessation is to be used together with all other interventions recognized as effective in tobacco control (cigarette and tobacco product pricing, regulatory approaches, smoking bans, health education)...
Smoking cessation: the role of bupropion among new pharmacologic agentsS Nardini
Pulmonary and TB Unit, General Hospital, Vittorio Veneto, TV, Italy
Monaldi Arch Chest Dis 56:467-72. 2001..In the future other drugs, active on the central nervous system, will be studied for smoking cessation, and the option of using bupropion and NRT together should be further explored...
Effect of assist negative pressure ventilation by microprocessor based iron lung on breathing effortM Gorini
Respiratory Intensive Care Unit, Careggi Hospital, Firenze, Italy
Thorax 57:258-62. 2002..This study was undertaken to evaluate the performance of a microprocessor based iron lung capable of thermistor triggering...
Clinical pharmacokinetics of salmeterolMario Cazzola
Department of Respiratory Medicine, A Cardarelli Hospital, Naples, Italy
Clin Pharmacokinet 41:19-30. 2002..This is an important point, because it has been demonstrated that the systemic effects of salmeterol are more likely to occur with higher doses, which lead to approximately proportionally increased blood concentrations...
Nasal potential difference in congenital bilateral absence of the vas deferensU Pradal
Cystic Fibrosis Center, Azienda Ospedaliera Verona, Verona, Italy
Am J Respir Crit Care Med 158:896-901. 1998..We suggest that CBAVD patients with altered NPD should undergo further clinical follow-up in order to detect possible late complications of CF...
