Michele Tinazzi

Summary

Country: Italy

Publications

  1. ncbi TENS for the treatment of writer's cramp dystonia: a randomized, placebo-controlled study
    M Tinazzi
    Unita Operativa di Neurologia, Azienda Ospedaliera di Verona, Verona, Italy
    Neurology 64:1946-8. 2005
  2. ncbi Task-specific impairment of motor cortical excitation and inhibition in patients with writer's cramp
    Michele Tinazzi
    Unita Operativa di Neurologia, Ospedale Civile Borgo Trento, Piazzale Stefani 1, 37100 Verona, Italy
    Neurosci Lett 378:55-8. 2005
  3. ncbi Clinical and [123I]FP-CIT SPET imaging follow-up in patients with drug-induced parkinsonism
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Universita di Verona, Verona, Italy
    J Neurol 256:910-5. 2009
  4. ncbi Effects of transcutaneous electrical nerve stimulation on motor cortex excitability in writer's cramp: neurophysiological and clinical correlations
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, , Italy
    Mov Disord 21:1908-13. 2006
  5. ncbi Muscular pain in Parkinson's disease and nociceptive processing assessed with CO2 laser-evoked potentials
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche, Universita di Verona, Verona, Italy
    Mov Disord 25:213-20. 2010
  6. ncbi Rapid modulation of cortical proprioceptive activity induced by transient cutaneous deafferentation: neurophysiological evidence of short-term plasticity across different somatosensory modalities in humans
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, , Italy
    Eur J Neurosci 18:3053-60. 2003
  7. ncbi Hyperalgesia and laser evoked potentials alterations in hemiparkinson: evidence for an abnormal nociceptive processing
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, Universita di Verona, Italy
    J Neurol Sci 276:153-8. 2009
  8. ncbi Defective temporal discrimination of passive movements in Parkinson's disease
    Mirta Fiorio
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, Universita di Verona, and Unità Operativa Neurologia Ospedale Civile Borgo Trento, Verona, Italy
    Neurosci Lett 417:312-5. 2007
  9. ncbi Subclinical sensory abnormalities in unaffected PINK1 heterozygotes
    Mirta Fiorio
    Dept of Neurological and Vision Sciences, Section of Rehabilitative Neurology, University of Verona, Via Casorati 43, 37131, Verona, Italy
    J Neurol 255:1372-7. 2008
  10. ncbi Long-lasting modulation of human motor cortex following prolonged transcutaneous electrical nerve stimulation (TENS) of forearm muscles: evidence of reciprocal inhibition and facilitation
    Michele Tinazzi
    Unità Operativa Neurologia, Ospedale Civile Borgo Trento, Piazzale Stefani 1, 37100 Verona, Italy
    Exp Brain Res 161:457-64. 2005

Collaborators

Detail Information

Publications52

  1. ncbi TENS for the treatment of writer's cramp dystonia: a randomized, placebo-controlled study
    M Tinazzi
    Unita Operativa di Neurologia, Azienda Ospedaliera di Verona, Verona, Italy
    Neurology 64:1946-8. 2005
    ..Patients were evaluated using four measures of dystonic impairment. The TENS group showed a significant improvement that persisted for 3 weeks in three of the four measures...
  2. ncbi Task-specific impairment of motor cortical excitation and inhibition in patients with writer's cramp
    Michele Tinazzi
    Unita Operativa di Neurologia, Ospedale Civile Borgo Trento, Piazzale Stefani 1, 37100 Verona, Italy
    Neurosci Lett 378:55-8. 2005
    ..These results indicate a task-specific impairment of motor cortical excitation and inhibition in writer's cramp...
  3. ncbi Clinical and [123I]FP-CIT SPET imaging follow-up in patients with drug-induced parkinsonism
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Universita di Verona, Verona, Italy
    J Neurol 256:910-5. 2009
    ..Patients with DIP may benefit from levodopa therapy, particularly when dopamine nerve terminal defects are present, and this should be considered in the therapeutic management of these patients...
  4. ncbi Effects of transcutaneous electrical nerve stimulation on motor cortex excitability in writer's cramp: neurophysiological and clinical correlations
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, , Italy
    Mov Disord 21:1908-13. 2006
    ..In conclusion, repeated TENS sessions may have the effect to re-modulate excitability of the motor cortex in WC and this modulation might partially play a role in temporarily improving the handwriting...
  5. ncbi Muscular pain in Parkinson's disease and nociceptive processing assessed with CO2 laser-evoked potentials
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche, Universita di Verona, Verona, Italy
    Mov Disord 25:213-20. 2010
    ..These results suggest abnormal nociceptive input processing in PD, which appears to be independent of clinical expression of parkinsonian motor signs. These alterations are more evident in the presence of muscular pain...
  6. ncbi Rapid modulation of cortical proprioceptive activity induced by transient cutaneous deafferentation: neurophysiological evidence of short-term plasticity across different somatosensory modalities in humans
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, , Italy
    Eur J Neurosci 18:3053-60. 2003
    ..Results show, for the first time in humans, that a transient cutaneous deafferentation may induce rapid modulation of cortical activity evoked by stimulation of muscle afferents originating in the anaesthetic territory...
  7. ncbi Hyperalgesia and laser evoked potentials alterations in hemiparkinson: evidence for an abnormal nociceptive processing
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, Universita di Verona, Italy
    J Neurol Sci 276:153-8. 2009
    ..These results suggest that in pain-free PD patients there is an abnormal nociceptive input processing that may be independent of the clinical expression of parkinsonian motor signs...
  8. ncbi Defective temporal discrimination of passive movements in Parkinson's disease
    Mirta Fiorio
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, Universita di Verona, and Unità Operativa Neurologia Ospedale Civile Borgo Trento, Verona, Italy
    Neurosci Lett 417:312-5. 2007
    ..Results showed that thresholds were significantly higher in PD patients than in control subjects for both FCR and FDI muscle, thus demonstrating for the first time that temporal proprioceptive processing is altered in PD...
  9. ncbi Subclinical sensory abnormalities in unaffected PINK1 heterozygotes
    Mirta Fiorio
    Dept of Neurological and Vision Sciences, Section of Rehabilitative Neurology, University of Verona, Via Casorati 43, 37131, Verona, Italy
    J Neurol 255:1372-7. 2008
    ....
  10. ncbi Long-lasting modulation of human motor cortex following prolonged transcutaneous electrical nerve stimulation (TENS) of forearm muscles: evidence of reciprocal inhibition and facilitation
    Michele Tinazzi
    Unità Operativa Neurologia, Ospedale Civile Borgo Trento, Piazzale Stefani 1, 37100 Verona, Italy
    Exp Brain Res 161:457-64. 2005
    ....
  11. ncbi Abnormal processing of the nociceptive input in Parkinson's disease: a study with CO2 laser evoked potentials
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, Universita di Verona, Italy
    Pain 136:117-24. 2008
    ..These results suggest an abnormal nociceptive input processing in pain-free PD patients which appears to be independent of clinical expression of parkinsonian motor signs and is not affected by dopaminergic stimulation...
  12. ncbi Temporal discrimination of two passive movements in writer's cramp
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, , Italy
    Mov Disord 21:1131-5. 2006
    ..We conclude that temporal processing of muscle and cutaneous afferents is differentially affected in focal hand dystonia...
  13. ncbi Temporal discrimination of two passive movements in humans: a new psychophysical approach to assessing kinaesthesia
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, Universita di Verona, Italy
    Exp Brain Res 166:184-9. 2005
    ..These results suggest that muscle, and in part cutaneous, afferents contribute to temporal discrimination of a dual movement. The technique may provide a useful way of measuring temporal discrimination of kinaesthetic inputs in humans...
  14. ncbi Lateral trunk flexion in Parkinson's disease: EMG features disclose two different underlying pathophysiological mechanisms
    Alessandro Di Matteo
    Dipartimento di Scienze Neurologiche e della Visione e UO di Neurologia Azienda Ospedaliera Universitaria integrata di Verona, Universita di Verona, Verona, Italy
    J Neurol 258:740-5. 2011
    ..Possible pathophysiologic mechanisms and treatment approaches are discussed...
  15. ncbi Role of the somatosensory system in primary dystonia
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, Verona, Italy
    Mov Disord 18:605-22. 2003
    ..Further studies have to be addressed to the assessment of the role of sensory modalities and their interaction on the pathophysiology of different forms of primary dystonia...
  16. ncbi Timing of tactile and visuo-tactile events is impaired in patients with cervical dystonia
    Michele Tinazzi
    , Ospedale Civile Borgo Trento, Piazzale Stefani 1, 37100 Verona, Italy
    J Neurol 251:85-90. 2004
    ..Thus, impairment of sensory timing may be a marker of disease, which varies along a continuum in the different forms of dystonia...
  17. ncbi Effect of balance training on postural instability in patients with idiopathic Parkinson's disease
    Nicola Smania
    Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, Verona, Italy
    Neurorehabil Neural Repair 24:826-34. 2010
    ..Postural instability (PI) is a disabling sign of Parkinson's disease (PD) not easily amenable to treatment with medication...
  18. ncbi Selective impairment of hand mental rotation in patients with focal hand dystonia
    Mirta Fiorio
    Dipartimento di Scienze Neurologiche e della Visione, Sezione Fisiologia Umana, , Verona, Italy
    Brain 129:47-54. 2006
    ....
  19. ncbi [123I]FP-CIT SPET imaging in drug-induced Parkinsonism
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Universita di Verona, Italy
    Mov Disord 23:1825-9. 2008
    ..Imaging of the dopamine transporter may help to identify subjects with DIP secondary to a loss of dopamine nerve terminals...
  20. ncbi Three-dimensional motion analysis of the effects of auditory cueing on gait pattern in patients with Parkinson's disease: a preliminary investigation
    Alessandro Picelli
    Neuromotor and Cognitive Rehabilitation Research Centre, University of Verona, Via L A Scuro, 10, 37134, Verona, Italy
    Neurol Sci 31:423-30. 2010
    ..Range of motion of the ankle joint decreased and the maximal values within the pull-off phase of the hip joint power increased. Thus, auditory cues could improve gait modifying motor strategy in parkinsonian patients...
  21. ncbi Defective temporal processing of sensory stimuli in DYT1 mutation carriers: a new endophenotype of dystonia?
    Mirta Fiorio
    Department of Neurological and Vision Sciences, Section of Rehabilitative Neurology, University of Verona, Verona, Italy
    Brain 130:134-42. 2007
    ....
  22. ncbi Does neurophysiological testing provide the information we need to improve the clinical management of primary dystonia?
    Michele Tinazzi
    Department of Neurological and Vision Sciences, University of Verona, Verona, Italy
    Clin Neurophysiol 120:1424-32. 2009
    ....
  23. ncbi Pisa syndrome without neuroleptic exposure in a patient with Parkinson's disease: case report
    Mattia Gambarin
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, , Verona, Italy
    Mov Disord 21:270-3. 2006
    ..Because dopamine transporter imaging revealed bilateral and symmetrical reduction of striatal uptake, we suggest that PS is not primarily related to side differences in dopaminergic denervation or drug exposure...
  24. ncbi Sensory functions in dystonia: insights from behavioral studies
    Michele Tinazzi
    Department of Neurological and Vision Sciences, University of Verona, Verona, Italy
    Mov Disord 24:1427-36. 2009
    ....
  25. ncbi Task-dependent modulation of excitatory and inhibitory functions within the human primary motor cortex
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, Universita di Verona, Policlinico G B Rossi, P le A L Scuro, 37134, Verona, Italy
    Exp Brain Res 150:222-9. 2003
    ..Increased cortical excitatory and inhibitory functions during precision tasks (pincer gripping) probably explain why MEPs have larger amplitudes and CSPs have longer durations during pincer gripping than during power gripping...
  26. ncbi Impaired heteronymous somatosensory motor cortical inhibition in dystonia
    Laura Bertolasi
    Department of Neurological Sciences and Vision, Section of Neurology, University of Verona, Verona, Italy
    Mov Disord 18:1367-73. 2003
    ....
  27. ncbi Abduction finger sign: a new sign to detect unilateral functional paralysis of the upper limb
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Universita di Verona, Italy
    Mov Disord 23:2415-9. 2008
    ..The abduction finger sign may be a reliable bedside test to discriminate functional from organic arm paralysis...
  28. ncbi The status of olfactory function and the striatal dopaminergic system in drug-induced parkinsonism
    Tommaso Bovi
    Dipartimento di Scienze Neurologiche e della Visione, Universita di Verona, Verona, Italy
    J Neurol 257:1882-9. 2010
    ..These preliminary results might have prognostic and therapeutic implications, as abnormalities in these individuals may be suggestive of an underlying PD-like neurodegenerative process...
  29. ncbi The effect of two different rehabilitation treatments in cervical dystonia: preliminary results in four patients
    Nicola Smania
    Center of Functional Reeducation, G B Rossi Hospital, Verona, Italy
    Funct Neurol 18:219-25. 2003
    ..These preliminary results suggest that the physiotherapy program proposed in the present study may be a promising method for rehabilitation of cervical dystonia...
  30. ncbi Focal motor seizures mimicking hemifacial spasm
    Cristina Deluca
    Dipartimento di Scienze Neurologiche e della Visione, Universita di Verona, Piazzale Scuro 9, 37134 Verona, Italy
    Parkinsonism Relat Disord 14:649-51. 2008
    ....
  31. ncbi Nociceptive pathway function is normal in cervical dystonia: a study using laser-evoked potentials
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche, Neuropsicologiche, Morfologiche e Motorie, Universita di Verona, 37100, Verona, Italy
    J Neurol 259:2060-6. 2012
    ....
  32. ncbi Temporal processing of visuotactile and tactile stimuli in writer's cramp
    Mirta Fiorio
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Fisiologia Umana, Italy
    Ann Neurol 53:630-5. 2003
    ..Deficits of temporal processing of stimuli delivered to the unaffected side may represent a behavioral index of the susceptibility to develop dystonia and thus have remarkable practical and theoretical implications...
  33. ncbi Functional plasticity in the human primary somatosensory cortex following acute lesion of the anterior lateral spinal cord: neurophysiological evidence of short-term cross-modal plasticity
    Tiziana Rosso
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, , Policlinico 'G B Rossi, P le A L Scuro, 37134, Verona, Italy
    Pain 101:117-27. 2003
    ....
  34. ncbi Pain-related modulation of the human motor cortex
    Simona Farina
    Dipartimento di Scienze Neurologiche e della Visione, Sez. di Neurologia Riabilitativa, Verona, Italy
    Neurol Res 25:130-42. 2003
    ..Further studies are required to assess the effects of pain on the motor system in patients suffering from chronic pain, in order to develop innovative rational therapeutic strategies to reduce both pain and motor disability...
  35. ncbi Deficits of temporal discrimination in dystonia are independent from the spatial distance between the loci of tactile stimulation
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sez. di Neurologia Riabilitativa, Verona, Italy
    Mov Disord 17:333-8. 2002
    ..Results extend current knowledge of deficits of somesthetic temporal discrimination in dystonia by showing that temporal deficits are not influenced by spatial variables...
  36. ncbi Therapeutic effects of peripheral repetitive magnetic stimulation on myofascial pain syndrome
    Nicola Smania
    Centro di Rieducazione Funzionale Policlinico G B Rossi, Verona, Italy
    Clin Neurophysiol 114:350-8. 2003
    ..To evaluate short- and medium-term effects of peripheral repetitive magnetic stimulation (rMS) on myofascial pain...
  37. ncbi Rehabilitation of sensorimotor integration deficits in balance impairment of patients with stroke hemiparesis: a before/after pilot study
    Nicola Smania
    Rehabilitation Unit, G B Rossi University Hospital, Via L A Scuro 10, Verona, Italy
    Neurol Sci 29:313-9. 2008
    ..These findings indicate that rehabilitation of sensorimotor integration deficits can improve balance in patients with stroke hemiparesis...
  38. ncbi Ataxia in posterior circulation stroke: clinical-MRI correlations
    Cristina Deluca
    Department of Neurological and Vision Sciences, University of Verona, Verona, Italy
    J Neurol Sci 300:39-46. 2011
    ..Although ataxia has been described in posterior circulation (PC) stroke series, there are no prospective studies that have investigated a possible differential role of the cerebellum or its input/outputs in causing ataxia...
  39. ncbi Paroxysmal exercise-induced dyskinesia with self-limiting partial epilepsy: a novel GLUT-1 mutation with benign phenotype
    Tommaso Bovi
    Dipartimento di Scienze Neurologiche e della Visione, Azienda Ospedaliera Universitaria Integrata di Verona, Italy
    Parkinsonism Relat Disord 17:479-81. 2011
    ..She carries a novel sporadic heterozygous mutation of the SLC2A1 gene. Diagnostic difficulties and possible treatment with carbamazepine are discussed...
  40. ncbi Palatal tremor suppressed by mouth opening: clinical and neurophysiological correlations in two patients
    Alberto Morini
    Unita Operativa di Neurologia, Ospedale Santa Chiara, Piazzale Medaglie d oro n degree 1, 38100 Trento, Italy
    J Neurol 252:1335-40. 2005
    ..We emphasize that clear cut modulating phenomena may be relevant features in both typical and atypical involuntary EPT. We finally focus on the significance of jaw posture in determining PT suppression in our patients...
  41. ncbi Limb ataxia and proximal intracranial territory brain infarcts: clinical and topographical correlations
    Cristina Deluca
    Dipartimento di Scienze Neurologiche e della Visione, Azienda Ospedaliera Universitaria di Verona, Italy
    J Neurol Neurosurg Psychiatry 78:832-5. 2007
    ..ICP and PICA territory cerebellar infarcts most often occur independently but occasionally occur together...
  42. ncbi Time-related changes of excitability of the human motor system contingent upon immobilisation of the ring and little fingers
    Stefano Facchini
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Fisiologia Umana, , Strada Le Grazie 8, 37134, Verona, Italy
    Clin Neurophysiol 113:367-75. 2002
    ....
  43. ncbi Somatosensory disinhibition in dystonia
    E Frasson
    Dipartimento di Scienze Neurologiche e della Visione, Sez. di Neurologia e Sez. di Neurologia Riabilitativa, Verona, Italy
    Mov Disord 16:674-82. 2001
    ....
  44. ncbi Expertise with pathological actions modulates a viewer's motor system
    M Fiorio
    Department of Neurological and Vision Sciences, University of Verona, Verona, Italy
    Neuroscience 167:691-9. 2010
    ..These findings suggest that observation of unusual pathological actions differently modulates the viewer's motor system, depending on knowledge, visual expertise, and ability in recognizing suboptimal movement kinematics...
  45. ncbi A modified constraint-induced movement therapy (CIT) program improves paretic arm use and function in children with cerebral palsy
    N Smania
    Department of Neurological and Vision Sciences, University of Verona, Verona, Italy
    Eur J Phys Rehabil Med 45:493-500. 2009
    ....
  46. ncbi Transient inhibition of the human motor cortex by capsaicin-induced pain. A study with transcranial magnetic stimulation
    S Farina
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, , Verona, Italy
    Neurosci Lett 314:97-101. 2001
    ..This inhibition may be due to the activation of the C fibres which mediate 'slow' nociception and might be important to alert subject to possible phasic nociceptive events that may occur close to the painful area...
  47. ncbi Tactile temporal discrimination in patients with blepharospasm
    M Fiorio
    Dipartimento di Scienze Neurologiche e della Visione, Sez Neurologia Riabilitativa, Universitè di Verona, Via Casorati 43, 37131 Verona, Italy
    J Neurol Neurosurg Psychiatry 79:796-8. 2008
    ..Blepharospasm is an adult-onset focal dystonia that causes involuntary blinking and eyelid spasms. Studies have shown the presence of sensory deficits associated with dystonia...
  48. ncbi Plastic interactions between hand and face cortical representations in patients with trigeminal neuralgia: a somatosensory-evoked potentials study
    M Tinazzi
    , Verona, Italy
    Neuroscience 127:769-76. 2004
    ..No changes were found in spinal N13 and brainstem P14. That facial pain is associated with neuroplastic changes within the somatic cortical representation of the hand suggests a pain-related topographic cortical reorganisation...
  49. ncbi Short-term plastic changes of the human nociceptive system following acute pain induced by capsaicin
    Massimiliano Valeriani
    Istituto di Neurologia, Universita Cattolica del Sacro Cuore, L go A Gemelli 8, 00168, Rome, Italy
    Clin Neurophysiol 114:1879-90. 2003
    ..To investigate possible neuroplastic changes induced by pain in cerebral areas devoted to nociceptive input processing...
  50. ncbi Inhibitory effect of capsaicin evoked trigeminal pain on warmth sensation and warmth evoked potentials
    Massimiliano Valeriani
    Divisione di Neurologia, Ospedale Pediatrico Bambino Gesu, IRCCS, Piazza Sant Onofrio 4, 00165 Rome, Italy
    Exp Brain Res 160:29-37. 2005
    ..This is the first neurophysiological evidence in humans of an inhibitory effect of pain on warmth sensation...
  51. ncbi Head trauma in primary cranial dystonias: a multicentre case-control study
    Davide Martino
    Department of Neurological and Psychiatric Sciences, University of Bari, Piazza Giulio Cesare, 11 70124 Bari, Italy
    J Neurol Neurosurg Psychiatry 78:260-3. 2007
    ..The relationship between prior trauma and primary adult-onset dystonia is not well understood. Previous uncontrolled observations and exploratory case-control studies have yielded contradictory results...
  52. ncbi Active finger extension: a simple movement predicting recovery of arm function in patients with acute stroke
    Nicola Smania
    Department of Neurological and Vision Sciences, Neurorehabilitation Section, University of Verona, Italy
    Stroke 38:1088-90. 2007
    ..Early prognosis of arm recovery is a major clinical issue in stroke. The aim of this study was to assess the prognostic value of 4 simple bedside tests...