Anna Maria Timperio

Summary

Country: Italy

Publications

  1. doi request reprint Analysis of the cattle liver proteome by high-sensitive liquid chromatography coupled with mass spectrometry method
    Anna Maria Timperio
    Department of Environmental Sciences, University of Tuscia, Largo dell Università snc, Viterbo, Italy
    Methods Mol Biol 909:43-62. 2012
  2. doi request reprint Acclimation to intense light implies changes at the level of trimeric subunits involved in the structural organization of the main light-harvesting complex of photosystem II (LHCII) and their isoforms
    Anna Maria Timperio
    Department of Ecology and Biology, Tuscia University, Largo dell Università snc, 01100 Viterbo, Italy
    Plant Physiol Biochem 50:8-14. 2012
  3. doi request reprint Production of the phytoalexins trans-resveratrol and delta-viniferin in two economy-relevant grape cultivars upon infection with Botrytis cinerea in field conditions
    Anna Maria Timperio
    Department of Environmental Science, Tuscia University, L go dell Università snc, 01100 Viterbo, Italy
    Plant Physiol Biochem 50:65-71. 2012
  4. pmc Comparison among plasma-derived clotting factor VIII by using monodimensional gel electrophoresis and mass spectrometry
    Anna Maria Timperio
    Dipartimento di Scienze Ambientali, Universita della Tuscia, Viterbo, Italy
    Blood Transfus 8:s98-104. 2010
  5. doi request reprint Comparative proteomics and transcriptomics analyses of livers from two different Bos taurus breeds: "Chianina and Holstein Friesian"
    Anna Maria Timperio
    Dipartimento Scienze Ambientali Università La Tuscia Viterbo, Italy
    J Proteomics 73:309-22. 2009
  6. ncbi request reprint Chemically enhanced liquid chromatography/tandem mass spectrometry determination of glutamic acid in the diffusion medium of retinal cells
    Anna Maria Timperio
    Department of Environmental Sciences, University La Tuscia L go dell Università snc 01100 Viterbo, Italy
    Biomed Chromatogr 21:1069-76. 2007
  7. doi request reprint Proteomic analysis of multiprotein complexes in the thylakoid membrane upon cadmium treatment
    Marco Fagioni
    Department of Environmental Sciences, Tuscia University, Viterbo, Italy
    J Proteome Res 8:310-26. 2009
  8. doi request reprint Modulation of the neuronal response to ischaemia by somatostatin analogues in wild-type and knock-out mouse retinas
    Davide Cervia
    Department of Environmental Sciences, University of Tuscia, Largo dell Università snc, Viterbo
    J Neurochem 106:2224-35. 2008
  9. ncbi request reprint Intact mass measurements for unequivocal identification of hydrophobic photosynthetic photosystems I and II antenna proteins
    Lello Zolla
    Department of Environmental Sciences, University of Tuscia, Viterbo, Italy
    Electrophoresis 25:1353-66. 2004
  10. ncbi request reprint Analysis of TAp73-dependent signaling via omics technologies
    Angelo D'Alessandro
    Department of Ecological and Biological Sciences, University of Tuscia, Largo dell Universita, snc, 01100 Viterbo, Italy
    J Proteome Res 12:4207-20. 2013

Collaborators

Detail Information

Publications31

  1. doi request reprint Analysis of the cattle liver proteome by high-sensitive liquid chromatography coupled with mass spectrometry method
    Anna Maria Timperio
    Department of Environmental Sciences, University of Tuscia, Largo dell Università snc, Viterbo, Italy
    Methods Mol Biol 909:43-62. 2012
    ..Thus, spots from 2-DE maps can be carefully excised from the gel and subjected to in-gel trypsin digestion and analyzed by tandem mass spectrometry in their contents...
  2. doi request reprint Acclimation to intense light implies changes at the level of trimeric subunits involved in the structural organization of the main light-harvesting complex of photosystem II (LHCII) and their isoforms
    Anna Maria Timperio
    Department of Ecology and Biology, Tuscia University, Largo dell Università snc, 01100 Viterbo, Italy
    Plant Physiol Biochem 50:8-14. 2012
    ..3) behaved differently in response to elevated light intensity, suggesting an essential role of these isoforms to light adaption and consequently explaining the presence of this multigenic family, often identified among higher plants...
  3. doi request reprint Production of the phytoalexins trans-resveratrol and delta-viniferin in two economy-relevant grape cultivars upon infection with Botrytis cinerea in field conditions
    Anna Maria Timperio
    Department of Environmental Science, Tuscia University, L go dell Università snc, 01100 Viterbo, Italy
    Plant Physiol Biochem 50:65-71. 2012
    ....
  4. pmc Comparison among plasma-derived clotting factor VIII by using monodimensional gel electrophoresis and mass spectrometry
    Anna Maria Timperio
    Dipartimento di Scienze Ambientali, Universita della Tuscia, Viterbo, Italy
    Blood Transfus 8:s98-104. 2010
    ..Thus, information regarding the presence of contaminants in commercial products is of concern...
  5. doi request reprint Comparative proteomics and transcriptomics analyses of livers from two different Bos taurus breeds: "Chianina and Holstein Friesian"
    Anna Maria Timperio
    Dipartimento Scienze Ambientali Università La Tuscia Viterbo, Italy
    J Proteomics 73:309-22. 2009
    ..In brief, our integrated study provides molecular evidences to support the physiological differences between Holstein and Chianina cattle breeds...
  6. ncbi request reprint Chemically enhanced liquid chromatography/tandem mass spectrometry determination of glutamic acid in the diffusion medium of retinal cells
    Anna Maria Timperio
    Department of Environmental Sciences, University La Tuscia L go dell Università snc 01100 Viterbo, Italy
    Biomed Chromatogr 21:1069-76. 2007
    ..This is the first report of using chemical derivatization to enhance MS/MS detection of the glutamic acid released in the diffusion medium of wild-type and mutant retina cells, under ischemic conditions...
  7. doi request reprint Proteomic analysis of multiprotein complexes in the thylakoid membrane upon cadmium treatment
    Marco Fagioni
    Department of Environmental Sciences, Tuscia University, Viterbo, Italy
    J Proteome Res 8:310-26. 2009
    ..1 antenna were observed, suggesting that Cd affects specifically the photosynthetic apparatus of spinach basal leaves, replacing other metal ions inside proteins...
  8. doi request reprint Modulation of the neuronal response to ischaemia by somatostatin analogues in wild-type and knock-out mouse retinas
    Davide Cervia
    Department of Environmental Sciences, University of Tuscia, Largo dell Università snc, Viterbo
    J Neurochem 106:2224-35. 2008
    ..These results demonstrate that sst(2) activation protects against retinal ischaemia. However, in the presence of sst(2) over-expression sst(2) is functionally desensitised by agonists, possibly because of sustained RGS1 levels...
  9. ncbi request reprint Intact mass measurements for unequivocal identification of hydrophobic photosynthetic photosystems I and II antenna proteins
    Lello Zolla
    Department of Environmental Sciences, University of Tuscia, Viterbo, Italy
    Electrophoresis 25:1353-66. 2004
    ..By utilizing this correlation, it was possible to spot gene products of previously cloned genes...
  10. ncbi request reprint Analysis of TAp73-dependent signaling via omics technologies
    Angelo D'Alessandro
    Department of Ecological and Biological Sciences, University of Tuscia, Largo dell Universita, snc, 01100 Viterbo, Italy
    J Proteome Res 12:4207-20. 2013
    ..In conclusion, the obtained results confirm existing evidence from transcriptomics analyses and suggest a role for TAp73α in the regulation of cellular metabolism, cell survival, and cell growth. ..
  11. pmc Comparison of milk fat globule membrane (MFGM) proteins of Chianina and Holstein cattle breed milk samples through proteomics methods
    Leonardo Murgiano
    Dipartimento Produzioni Animali, Universita degli Studi della Tuscia, Viterbo, 01100, Italy
    Nutrients 1:302-15. 2009
    ..We have shown that proteomics is a suitable, unbiased method for the study of milk fractions proteins and a powerful tool in nutritional genomics...
  12. doi request reprint Coupling of native liquid phase isoelectrofocusing and blue native polyacrylamide gel electrophoresis: a potent tool for native membrane multiprotein complex separation
    Gian Maria D'Amici
    Department of Environmental Sciences, Tuscia University, Viterbo, Italy
    J Proteome Res 7:1326-40. 2008
    ..SDS-PAGE revealed almost all the subunits from the four photosynthetic complexes, indicating that by using 3D N-LP-IEF-BN-SDS-PAGE it is possible to achieve a greater degree of component identification than with 2D BN-SDS-PAGE...
  13. doi request reprint Proteomics and transcriptomics investigation on longissimus muscles in Large White and Casertana pig breeds
    Leonardo Murgiano
    Dipartimento di Produzioni Animali, Università della Tuscia, Via de Lellis, 01100 Viterbo, Italy
    J Proteome Res 9:6450-66. 2010
    ..Large White overexpressed cell cycle and skeletal muscle growth related genes. Metabolic behavior and other implications are discussed...
  14. ncbi request reprint Separation and identification of the light harvesting proteins contained in grana and stroma thylakoid membrane fractions
    Anna Maria Timperio
    Department of Environmental Sciences, University of Tuscia, 01100 Viterbo, Italy
    J Chromatogr A 1040:73-81. 2004
    ..Such investigations could not be performed by sodium dodecylsulfate-polyacrylamide gel electrophoresis because of insufficient resolution of the proteins having molecular masses between 22,000 and 25,000...
  15. ncbi request reprint Cadmium stress responses in Brassica juncea: hints from proteomics and metabolomics
    Angelo D'Alessandro
    Department of Ecological and Biological Sciences, University of Tuscia, Largo dell Universita, snc, 01100 Viterbo, Italy
    J Proteome Res 12:4979-97. 2013
    ..Overall, it emerges that Cd-stressed B. juncea might rely on photorespiration, an adaptation that would prevent the over-reduction of the photosynthetic electron transport chain and photoinhibition. ..
  16. ncbi request reprint Proteomic analysis of photosystem I components from different plant species
    Lello Zolla
    Department of Environmental Sciences, University of Tuscia, Viterbo, Italy
    Proteomics 7:1866-76. 2007
    ..Small proteins like Psa-I and Psa-J are well separated and identified. RP-HPLC produces reliable fingerprints and reveals that the relative amounts of PSI proteins appear to be markedly different...
  17. pmc Proteomics of light-harvesting proteins in different plant species. Analysis and comparison by liquid chromatography-electrospray ionization mass spectrometry. Photosystem II
    Lello Zolla
    Department of Environmental Sciences, University of Tuscia, 01100 Viterbo, Italy
    Plant Physiol 131:198-214. 2003
    ....
  18. ncbi request reprint Hydrazide derivatives produce active oxygen species as hydrazine
    Anna Maria Timperio
    Department of Environmental Sciences, University of Tuscia, Viterbo, Italy
    Bioorg Chem 33:459-69. 2005
    ..Data reported here demonstrate that hydrazides cause irreversible damage to the prosthetic group of proteins as well as causing degradation of the polypeptide chain into small fragments...
  19. doi request reprint Recombinant clotting factor VIII concentrates: Heterogeneity and high-purity evaluation
    Gian Maria D'Amici
    Department of Environmental Sciences, Tuscia University, Viterbo, Italy
    Electrophoresis 31:2730-9. 2010
    ..The proteomic approach will contribute to improving the quality assurance and manufacturing processes of rFVIII concentrates. In this view, the 2-DE is mandatory for revealing the presence of contaminants...
  20. ncbi request reprint Proteomics, pigment composition, and organization of thylakoid membranes in iron-deficient spinach leaves
    Anna Maria Timperio
    Dipartimento di Scienze Ambientali, Università La Tuscia, L go dell Università, 01100 Viterbo, Italy
    J Exp Bot 58:3695-710. 2007
    ....
  21. doi request reprint Crosstalk between salicylic acid and jasmonate in Arabidopsis investigated by an integrated proteomic and transcriptomic approach
    Silvia Proietti
    Department of Ecological and Biological Sciences, Universita della Tuscia, Via S Camillo de Lellis, Viterbo 01100, Italy
    Mol Biosyst 9:1169-87. 2013
    ....
  22. ncbi request reprint Changes in neuronal response to ischemia in retinas with genetic alterations of somatostatin receptor expression
    Elisabetta Catalani
    Dipartimento di Scienze Ambientali, Universita della Tuscia, Largo dell Università snc, Blocco D, 01100 Viterbo, Italy
    Eur J Neurosci 25:1447-59. 2007
    ....
  23. doi request reprint Combinatorial peptide ligand libraries to discover liver disease biomarkers in plasma samples
    Gian Maria D'Amici
    Department of Environmental Sciences, University of Tuscia, Largo dell Università snc, Viterbo, Italy
    Methods Mol Biol 909:311-9. 2012
    ..This approach allowed us to identify plasma gelsolin as possible candidate biomarker for hepatitis B-associated liver cirrhosis...
  24. pmc Proteomics of light-harvesting proteins in different plant species. Analysis and comparison by liquid chromatography-electrospray ionization mass spectrometry. Photosystem I
    Lello Zolla
    Department of Environmental Sciences, University of Tuscia, Viterbo, Italy
    Plant Physiol 130:1938-50. 2002
    ..The HPLC method used in this study was found to be highly reproducible, and the chromatograms may serve as a highly confident fingerprint for comparison within a single and among different species for future studies of the PSI antenna...
  25. ncbi request reprint Assay of ochratoxin A in grape by high-pressure liquid chromatography coupled on line with an ESI-mass spectrometry
    Anna Maria Timperio
    Department of Environmental Sciences, University of Tuscia, 01100 Viterbo, Italy
    J Chromatogr B Analyt Technol Biomed Life Sci 832:127-33. 2006
    ..The method has a high sample extraction throughput (24/h) and has adequate precision (between batch C.V. <8%) and sensitivity (limit of detection (LOD)=1 pg/g; limits of quantification (LOQ)=2 pg/g) for OTA measured...
  26. doi request reprint Docosohaexanoic acid-supplemented PACA44 cell lines and over-activation of Krebs cycle: an integrated proteomic, metabolomic and interactomic overview
    Angelo D'Alessandro
    Department of Ecological and Biological Science, University of Tuscia, Viterbo, Italy
    J Proteomics 74:2138-58. 2011
    ..Interestingly, it also emerges a role for structural protein alteration in DHA-treated cells, which might be linked to cytoskeletal alterations occurring during apoptosis...
  27. ncbi request reprint Separation and identification of photosynthetic antenna membrane proteins by high- performance liquid chromatography electrospray ionization mass spectrometry
    Lello Zolla
    Department of Environmental Sciences, University of Tuscia, 01100 Viterbo, Italy
    Eur J Mass Spectrom (Chichester, Eng) 10:321-33. 2004
    ....
  28. doi request reprint Proteomics applied on plant abiotic stresses: role of heat shock proteins (HSP)
    Anna Maria Timperio
    Department of Environmental Sciences, University of Tuscia, Largo dell Università snc, 01100 Viterbo, Italy
    J Proteomics 71:391-411. 2008
    ....
  29. ncbi request reprint Involvement of active oxygen species in protein and oligonucleotide degradation induced by nitrofurans
    Lello Zolla
    Department of Environmental Science, University of Tuscia, Viterbo, Italy
    Biochem Cell Biol 83:166-75. 2005
    ..The reaction does not require metal ions, although their presence will accelerate it...
  30. doi request reprint A monoclonal antibody for the CD45 receptor in the teleost fish Dicentrarchus labrax
    Catia Marozzi
    Department for Innovation in Biological, Agro food and Forest systems, University of Tuscia, 01100 Viterbo, Italy
    Dev Comp Immunol 37:342-53. 2012
    ....
  31. ncbi request reprint Exploring the platelet proteome via combinatorial, hexapeptide ligand libraries
    Luc Guerrier
    Bio Rad Laboratories, C o CEA Saclay, 91191 Gif sur Yvette Cedex, France
    J Proteome Res 6:4290-303. 2007
    ..Thus, our list reports essentially hydrophilic proteins, with negative GRAVY indexes...